DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-9708296)

Number of enzymes:	3
Number of disease:	8
Number of reactomes:	7
Number of reactions:	14

Search results (Reactome ID: R-HSA-9708296)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007681	DICER1	Q9UPY3	3.1.26.3	R-HSA-9708296 R-HSA-9708296 Reactome Name: tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis See in Reactome R-HSA-426486 R-HSA-426486 Reactome Name: Small interfering RNA (siRNA) biogenesis See in Reactome R-HSA-203927 R-HSA-203927 Reactome Name: MicroRNA (miRNA) biogenesis See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome	Gene expression (Transcription)	R-HSA-203862 ( R-HSA-203927 ) R-HSA-203862 Reaction Name: Dicer cleaves pre-miRNA to yield duplex miRNA See in Reactome R-HSA-2106614 ( R-HSA-203927 ) R-HSA-2106614 Reaction Name: Duplex miRNA is loaded into Argonaute See in Reactome R-HSA-2106615 ( R-HSA-426486 ) R-HSA-2106615 Reaction Name: Removal of siRNA passenger strand See in Reactome R-HSA-2106625 ( R-HSA-426486 ) R-HSA-2106625 Reaction Name: Duplex siRNA is loaded into Argonaute See in Reactome R-HSA-210805 ( R-HSA-203927 ) R-HSA-210805 Reaction Name: Removal of miRNA passenger strand See in Reactome R-HSA-426464 ( R-HSA-426486 ) R-HSA-426464 Reaction Name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA See in Reactome R-HSA-9708292 ( R-HSA-9708296 ) R-HSA-9708292 Reaction Name: DICER1 cleaves tRNA See in Reactome R-HSA-9708408 ( R-HSA-9708296 ) R-HSA-9708408 Reaction Name: DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid See in Reactome
MONDO:0011014	DICER1	Q9UPY3	3.1.26.3	R-HSA-9708296 R-HSA-9708296 Reactome Name: tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis See in Reactome R-HSA-426486 R-HSA-426486 Reactome Name: Small interfering RNA (siRNA) biogenesis See in Reactome R-HSA-203927 R-HSA-203927 Reactome Name: MicroRNA (miRNA) biogenesis See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome	Gene expression (Transcription)	R-HSA-203862 ( R-HSA-203927 ) R-HSA-203862 Reaction Name: Dicer cleaves pre-miRNA to yield duplex miRNA See in Reactome R-HSA-2106614 ( R-HSA-203927 ) R-HSA-2106614 Reaction Name: Duplex miRNA is loaded into Argonaute See in Reactome R-HSA-2106615 ( R-HSA-426486 ) R-HSA-2106615 Reaction Name: Removal of siRNA passenger strand See in Reactome R-HSA-2106625 ( R-HSA-426486 ) R-HSA-2106625 Reaction Name: Duplex siRNA is loaded into Argonaute See in Reactome R-HSA-210805 ( R-HSA-203927 ) R-HSA-210805 Reaction Name: Removal of miRNA passenger strand See in Reactome R-HSA-426464 ( R-HSA-426486 ) R-HSA-426464 Reaction Name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA See in Reactome R-HSA-9708292 ( R-HSA-9708296 ) R-HSA-9708292 Reaction Name: DICER1 cleaves tRNA See in Reactome R-HSA-9708408 ( R-HSA-9708296 ) R-HSA-9708408 Reaction Name: DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid See in Reactome
MONDO:0012753	ANG	P03950	3.1.27.-	R-HSA-9708296 R-HSA-9708296 Reactome Name: tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis See in Reactome R-HSA-418990 R-HSA-418990 Reactome Name: Adherens junctions interactions See in Reactome	R-HSA-1500931 R-HSA-1500931 Reactome Name: Cell-Cell communication See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome R-HSA-421270 R-HSA-421270 Reactome Name: Cell-cell junction organization See in Reactome R-HSA-446728 R-HSA-446728 Reactome Name: Cell junction organization See in Reactome	Cell-Cell communication Gene expression (Transcription)	R-HSA-5692437 ( R-HSA-418990 ) R-HSA-5692437 Reaction Name: ANG binds F-actin See in Reactome R-HSA-9708327 ( R-HSA-9708296 ) R-HSA-9708327 Reaction Name: ANG cleaves tRNA to yield tRNA halves See in Reactome
MONDO:0013872	ELAC2	Q9BQ52	3.1.26.11	R-HSA-9708296 R-HSA-9708296 Reactome Name: tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis See in Reactome R-HSA-6785470 R-HSA-6785470 Reactome Name: tRNA processing in the mitochondrion See in Reactome R-HSA-6784531 R-HSA-6784531 Reactome Name: tRNA processing in the nucleus See in Reactome R-HSA-8868766 R-HSA-8868766 Reactome Name: rRNA processing in the mitochondrion See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome R-HSA-72312 R-HSA-72312 Reactome Name: rRNA processing See in Reactome R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome	Gene expression (Transcription) Metabolism of RNA	R-HSA-5696815 ( R-HSA-6784531 ) R-HSA-5696815 Reaction Name: ELAC2 cleaves the 3' end of pre-tRNA See in Reactome R-HSA-6785722 ( R-HSA-6785470; R-HSA-8868766 ) R-HSA-6785722 Reaction Name: Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript See in Reactome R-HSA-6786854 ( R-HSA-6785470 ) R-HSA-6786854 Reaction Name: Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript See in Reactome R-HSA-9708812 ( R-HSA-9708296 ) R-HSA-9708812 Reaction Name: ELAC2 cleaves pre-tRNA to yield 3' trailer (type II tRF or tRF-1) See in Reactome
MONDO:0014190	ELAC2	Q9BQ52	3.1.26.11	R-HSA-9708296 R-HSA-9708296 Reactome Name: tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis See in Reactome R-HSA-6785470 R-HSA-6785470 Reactome Name: tRNA processing in the mitochondrion See in Reactome R-HSA-6784531 R-HSA-6784531 Reactome Name: tRNA processing in the nucleus See in Reactome R-HSA-8868766 R-HSA-8868766 Reactome Name: rRNA processing in the mitochondrion See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome R-HSA-72312 R-HSA-72312 Reactome Name: rRNA processing See in Reactome R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome	Gene expression (Transcription) Metabolism of RNA	R-HSA-5696815 ( R-HSA-6784531 ) R-HSA-5696815 Reaction Name: ELAC2 cleaves the 3' end of pre-tRNA See in Reactome R-HSA-6785722 ( R-HSA-6785470; R-HSA-8868766 ) R-HSA-6785722 Reaction Name: Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript See in Reactome R-HSA-6786854 ( R-HSA-6785470 ) R-HSA-6786854 Reaction Name: Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript See in Reactome R-HSA-9708812 ( R-HSA-9708296 ) R-HSA-9708812 Reaction Name: ELAC2 cleaves pre-tRNA to yield 3' trailer (type II tRF or tRF-1) See in Reactome
MONDO:0017288	DICER1	Q9UPY3	3.1.26.3	R-HSA-9708296 R-HSA-9708296 Reactome Name: tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis See in Reactome R-HSA-426486 R-HSA-426486 Reactome Name: Small interfering RNA (siRNA) biogenesis See in Reactome R-HSA-203927 R-HSA-203927 Reactome Name: MicroRNA (miRNA) biogenesis See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome	Gene expression (Transcription)	R-HSA-203862 ( R-HSA-203927 ) R-HSA-203862 Reaction Name: Dicer cleaves pre-miRNA to yield duplex miRNA See in Reactome R-HSA-2106614 ( R-HSA-203927 ) R-HSA-2106614 Reaction Name: Duplex miRNA is loaded into Argonaute See in Reactome R-HSA-2106615 ( R-HSA-426486 ) R-HSA-2106615 Reaction Name: Removal of siRNA passenger strand See in Reactome R-HSA-2106625 ( R-HSA-426486 ) R-HSA-2106625 Reaction Name: Duplex siRNA is loaded into Argonaute See in Reactome R-HSA-210805 ( R-HSA-203927 ) R-HSA-210805 Reaction Name: Removal of miRNA passenger strand See in Reactome R-HSA-426464 ( R-HSA-426486 ) R-HSA-426464 Reaction Name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA See in Reactome R-HSA-9708292 ( R-HSA-9708296 ) R-HSA-9708292 Reaction Name: DICER1 cleaves tRNA See in Reactome R-HSA-9708408 ( R-HSA-9708296 ) R-HSA-9708408 Reaction Name: DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid See in Reactome
MONDO:0018445	DICER1	Q9UPY3	3.1.26.3	R-HSA-9708296 R-HSA-9708296 Reactome Name: tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis See in Reactome R-HSA-426486 R-HSA-426486 Reactome Name: Small interfering RNA (siRNA) biogenesis See in Reactome R-HSA-203927 R-HSA-203927 Reactome Name: MicroRNA (miRNA) biogenesis See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome	Gene expression (Transcription)	R-HSA-203862 ( R-HSA-203927 ) R-HSA-203862 Reaction Name: Dicer cleaves pre-miRNA to yield duplex miRNA See in Reactome R-HSA-2106614 ( R-HSA-203927 ) R-HSA-2106614 Reaction Name: Duplex miRNA is loaded into Argonaute See in Reactome R-HSA-2106615 ( R-HSA-426486 ) R-HSA-2106615 Reaction Name: Removal of siRNA passenger strand See in Reactome R-HSA-2106625 ( R-HSA-426486 ) R-HSA-2106625 Reaction Name: Duplex siRNA is loaded into Argonaute See in Reactome R-HSA-210805 ( R-HSA-203927 ) R-HSA-210805 Reaction Name: Removal of miRNA passenger strand See in Reactome R-HSA-426464 ( R-HSA-426486 ) R-HSA-426464 Reaction Name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA See in Reactome R-HSA-9708292 ( R-HSA-9708296 ) R-HSA-9708292 Reaction Name: DICER1 cleaves tRNA See in Reactome R-HSA-9708408 ( R-HSA-9708296 ) R-HSA-9708408 Reaction Name: DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid See in Reactome
MONDO:0032647	DICER1	Q9UPY3	3.1.26.3	R-HSA-9708296 R-HSA-9708296 Reactome Name: tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis See in Reactome R-HSA-426486 R-HSA-426486 Reactome Name: Small interfering RNA (siRNA) biogenesis See in Reactome R-HSA-203927 R-HSA-203927 Reactome Name: MicroRNA (miRNA) biogenesis See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome	Gene expression (Transcription)	R-HSA-203862 ( R-HSA-203927 ) R-HSA-203862 Reaction Name: Dicer cleaves pre-miRNA to yield duplex miRNA See in Reactome R-HSA-2106614 ( R-HSA-203927 ) R-HSA-2106614 Reaction Name: Duplex miRNA is loaded into Argonaute See in Reactome R-HSA-2106615 ( R-HSA-426486 ) R-HSA-2106615 Reaction Name: Removal of siRNA passenger strand See in Reactome R-HSA-2106625 ( R-HSA-426486 ) R-HSA-2106625 Reaction Name: Duplex siRNA is loaded into Argonaute See in Reactome R-HSA-210805 ( R-HSA-203927 ) R-HSA-210805 Reaction Name: Removal of miRNA passenger strand See in Reactome R-HSA-426464 ( R-HSA-426486 ) R-HSA-426464 Reaction Name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA See in Reactome R-HSA-9708292 ( R-HSA-9708296 ) R-HSA-9708292 Reaction Name: DICER1 cleaves tRNA See in Reactome R-HSA-9708408 ( R-HSA-9708296 ) R-HSA-9708408 Reaction Name: DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid See in Reactome