DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-9620244)

Number of enzymes:	5
Number of disease:	12
Number of reactomes:	80
Number of reactions:	168

Search results (Reactome ID: R-HSA-9620244)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0005105	ERBB4	Q15303	2.7.10.1	R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-1963640 R-HSA-1963640 Reactome Name: GRB2 events in ERBB2 signaling See in Reactome R-HSA-1257604 R-HSA-1257604 Reactome Name: PIP3 activates AKT signaling See in Reactome R-HSA-1250347 R-HSA-1250347 Reactome Name: SHC1 events in ERBB4 signaling See in Reactome R-HSA-1250342 R-HSA-1250342 Reactome Name: PI3K events in ERBB4 signaling See in Reactome R-HSA-1963642 R-HSA-1963642 Reactome Name: PI3K events in ERBB2 signaling See in Reactome R-HSA-6785631 R-HSA-6785631 Reactome Name: ERBB2 Regulates Cell Motility See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-6811558 R-HSA-6811558 Reactome Name: PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling See in Reactome R-HSA-1250196 R-HSA-1250196 Reactome Name: SHC1 events in ERBB2 signaling See in Reactome R-HSA-1227986 R-HSA-1227986 Reactome Name: Signaling by ERBB2 See in Reactome R-HSA-1236394 R-HSA-1236394 Reactome Name: Signaling by ERBB4 See in Reactome R-HSA-1253288 R-HSA-1253288 Reactome Name: Downregulation of ERBB4 signaling See in Reactome R-HSA-8847993 R-HSA-8847993 Reactome Name: ERBB2 Activates PTK6 Signaling See in Reactome R-HSA-8863795 R-HSA-8863795 Reactome Name: Downregulation of ERBB2 signaling See in Reactome R-HSA-1251985 R-HSA-1251985 Reactome Name: Nuclear signaling by ERBB4 See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-199418 R-HSA-199418 Reactome Name: Negative regulation of the PI3K/AKT network See in Reactome R-HSA-8848021 R-HSA-8848021 Reactome Name: Signaling by PTK6 See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-9006927 R-HSA-9006927 Reactome Name: Signaling by Non-Receptor Tyrosine Kinases See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Neuronal System Signal Transduction	R-HSA-1236398 ( R-HSA-1236394 ) R-HSA-1236398 Reaction Name: ERBB4 binds NRGs or EGF-like ligands See in Reactome R-HSA-1250195 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1250195 Reaction Name: SHC1 phosphorylation by ERBB2 heterodimers See in Reactome R-HSA-1250220 ( R-HSA-1236394 ) R-HSA-1250220 Reaction Name: Homodimerization of ERBB4 See in Reactome R-HSA-1250315 ( R-HSA-1236394 ) R-HSA-1250315 Reaction Name: Trans-autophosphorylation of ERBB4 homodimers See in Reactome R-HSA-1250346 ( R-HSA-1227986; R-HSA-1963642 ) R-HSA-1250346 Reaction Name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers See in Reactome R-HSA-1250348 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250348 Reaction Name: Phosphorylation of SHC1 by ERBB4 homodimers See in Reactome R-HSA-1250353 ( R-HSA-1236394; R-HSA-1250342 ) R-HSA-1250353 Reaction Name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers See in Reactome R-HSA-1250357 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250357 Reaction Name: SHC1 binds P-ERBB4 isoform dimers See in Reactome R-HSA-1250370 ( R-HSA-1236394; R-HSA-1250342 ) R-HSA-1250370 Reaction Name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers See in Reactome R-HSA-1250380 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250380 Reaction Name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers See in Reactome R-HSA-1250383 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250383 Reaction Name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349 See in Reactome R-HSA-1250383 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250383 Reaction Name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 See in Reactome R-HSA-1250463 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1250463 Reaction Name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers See in Reactome R-HSA-1250486 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1250486 Reaction Name: Recruitment of GRB2:SOS1 to p-SHC1 in complex with phosphorylated ERBB2 heterodimers See in Reactome R-HSA-1251992 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1251992 Reaction Name: Cleavage of P-ERBB4jmA isoforms by ADAM17 See in Reactome R-HSA-1251997 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1251997 Reaction Name: Cleavage of ERBB4m80 by gamma-scretase complex See in Reactome R-HSA-1252013 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1252013 Reaction Name: Translocation of ERBB4s80 to the nucleus See in Reactome R-HSA-1253282 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1253282 Reaction Name: ERBB4 ubiquitination by WWP1/ITCH See in Reactome R-HSA-1253300 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1253300 Reaction Name: ERBB4 binds WWP1/ITCH ubiquitin ligases See in Reactome R-HSA-1253319 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253319 Reaction Name: ERBB4s80:TAB2:NCOR1 complex translocates to the nucleus See in Reactome R-HSA-1253321 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253321 Reaction Name: GFAP gene expression is inhibited by ERBB4:TAB2:NCOR1 See in Reactome R-HSA-1253325 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253325 Reaction Name: ERBB4s80 binds TAB2:NCOR1 complex See in Reactome R-HSA-1253343 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253343 Reaction Name: WWOX binds ERBB4s80 See in Reactome R-HSA-1254248 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254248 Reaction Name: Translocation of ERBB4s80:YAP1 complex to the nucleus See in Reactome R-HSA-1254251 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254251 Reaction Name: ERBB4s80 binds YAP1 See in Reactome R-HSA-1254285 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254285 Reaction Name: ERBB4s80:STAT5A complex translocates to the nucleus See in Reactome R-HSA-1254290 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254290 Reaction Name: CSN2 gene expression is stimulated by ERBB4s80:STAT5A See in Reactome R-HSA-1254291 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254291 Reaction Name: ERBB4s80 binds STAT5A See in Reactome R-HSA-1254376 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254376 Reaction Name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix See in Reactome R-HSA-1254386 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-1254386 Reaction Name: ERBB4s80 forms a complex with estrogen receptor ESR1 See in Reactome R-HSA-1254392 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-1254392 Reaction Name: PGR gene expression is stimulated by ERBB4s80:ESR1:estrogen See in Reactome R-HSA-1306969 ( R-HSA-1227986; R-HSA-1963640 ) R-HSA-1306969 Reaction Name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers See in Reactome R-HSA-1306972 ( R-HSA-1227986; R-HSA-1963640 ) R-HSA-1306972 Reaction Name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers See in Reactome R-HSA-1306979 ( R-HSA-1227986; R-HSA-1963642 ) R-HSA-1306979 Reaction Name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 See in Reactome R-HSA-1963563 ( R-HSA-1227986; R-HSA-8863795 ) R-HSA-1963563 Reaction Name: MATK (CSK homologous kinase) binds phosphorylated ERBB2 See in Reactome R-HSA-1963578 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1963578 Reaction Name: SHC1 binds phosphorylated ERBB2 heterodimers See in Reactome R-HSA-1963581 ( R-HSA-1227986 ) R-HSA-1963581 Reaction Name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers See in Reactome R-HSA-1963582 ( R-HSA-1227986 ) R-HSA-1963582 Reaction Name: Trans-autophosphorylation of ERBB2 heterodimers See in Reactome R-HSA-1963586 ( R-HSA-1227986 ) R-HSA-1963586 Reaction Name: SRC family kinases phosphorylate ERBB2 See in Reactome R-HSA-1963589 ( R-HSA-1227986 ) R-HSA-1963589 Reaction Name: ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR See in Reactome R-HSA-1963589 ( R-HSA-1227986 ) R-HSA-1963589 Reaction Name: ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 See in Reactome R-HSA-1973956 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1973956 Reaction Name: NEDD4 binds ERBB4jmAcyt1s80 dimer See in Reactome R-HSA-1977296 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1977296 Reaction Name: NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer See in Reactome R-HSA-1977958 ( R-HSA-1236394 ) R-HSA-1977958 Reaction Name: ERBB4 forms heterodimers with ERBB3 See in Reactome R-HSA-1977959 ( R-HSA-1236394 ) R-HSA-1977959 Reaction Name: ERBB4 forms heterodimers with EGFR See in Reactome R-HSA-2316434 ( R-HSA-1257604; R-HSA-6811558 ) R-HSA-2316434 Reaction Name: PI3K phosphorylates PIP2 to PIP3 See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-6785636 ( R-HSA-1227986; R-HSA-6785631 ) R-HSA-6785636 Reaction Name: Phosphorylated ERBB2 heterodimers bind MEMO1 See in Reactome R-HSA-6785648 ( R-HSA-1227986; R-HSA-6785631 ) R-HSA-6785648 Reaction Name: MEMO1 binds RHOA:GTP:DIAPH1 See in Reactome R-HSA-8847995 ( R-HSA-1227986; R-HSA-8847993 ) R-HSA-8847995 Reaction Name: Activated ERBB2 binds PTK6 (BRK) See in Reactome R-HSA-8848005 ( R-HSA-1227986; R-HSA-8847993 ) R-HSA-8848005 Reaction Name: ERBB2 promotes PTK6 autophosphorylation See in Reactome R-HSA-8863804 ( R-HSA-1227986; R-HSA-8863795 ) R-HSA-8863804 Reaction Name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 See in Reactome R-HSA-8954179 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954179 Reaction Name: S100B gene expression is inhibited by ERBB4:TAB2:NCOR1 See in Reactome R-HSA-8954182 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954182 Reaction Name: ERBB4s80:TAB2:NCOR1 complex binds S100B gene promoter See in Reactome R-HSA-8954185 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954185 Reaction Name: ERBB4s80:TAB2:NCOR1 complex binds GFAP gene promoter See in Reactome R-HSA-8954199 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-8954199 Reaction Name: CXCL12 gene expression is stimulated by ERBB4s80:ESR1:estrogen See in Reactome R-HSA-8954207 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-8954207 Reaction Name: ERBB4s80:ESR1 binds CXCL12 gene promoter See in Reactome R-HSA-8954208 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-8954208 Reaction Name: ERBB4s80:ESR1 binds PGR gene promoter See in Reactome R-HSA-8954224 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954224 Reaction Name: ERBB4s80:STAT5A binds CSN2 gene promoter See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9612219 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-9612219 Reaction Name: ERBB4s80 binds to SRC See in Reactome R-HSA-9612243 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612243 Reaction Name: APOE gene transcription is stimulated by ERBB4s80 See in Reactome R-HSA-9612246 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612246 Reaction Name: ERBB4s80 binds the APOE gene See in Reactome R-HSA-9612255 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612255 Reaction Name: ERBB4s80 binds ADAP1 gene See in Reactome R-HSA-9612257 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612257 Reaction Name: ADAP1 gene expression is inhibited by ERBB4s80 See in Reactome R-HSA-9612277 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612277 Reaction Name: SPARC gene transcription is stimulated by ERBB4s80 See in Reactome R-HSA-9612278 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612278 Reaction Name: ERBB4s80 binds SPARC gene See in Reactome R-HSA-9612440 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612440 Reaction Name: ERBB4s80 binds the MXD4 gene See in Reactome R-HSA-9612444 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612444 Reaction Name: ERBB4s80 binds STMN1 gene See in Reactome R-HSA-9612445 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612445 Reaction Name: STMN1 gene expression is stimulated by ERBB4s80 See in Reactome R-HSA-9612448 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612448 Reaction Name: MXD4 gene expression is stimulated by ERBB4s80 See in Reactome R-HSA-9612593 ( R-HSA-1236394 ) R-HSA-9612593 Reaction Name: ERBB4 binds DLG4 See in Reactome R-HSA-9612639 ( R-HSA-1236394 ) R-HSA-9612639 Reaction Name: NRG2-activated ERBB4 binds GABA receptors through GABRA1 See in Reactome R-HSA-9612671 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612671 Reaction Name: ERBB4 gene expression is stimulated by ERBB4s80:ESR1 See in Reactome R-HSA-9612672 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612672 Reaction Name: ERBB4s80:ESR1 binds ERBB4 gene promoter See in Reactome
MONDO:0005298	SRC	P12931	2.7.10.2	R-HSA-418886 R-HSA-418886 Reactome Name: Netrin mediated repulsion signals See in Reactome R-HSA-171007 R-HSA-171007 Reactome Name: p38MAPK events See in Reactome R-HSA-428542 R-HSA-428542 Reactome Name: Regulation of commissural axon pathfinding by SLIT and ROBO See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-8940973 R-HSA-8940973 Reactome Name: RUNX2 regulates osteoblast differentiation See in Reactome R-HSA-418885 R-HSA-418885 Reactome Name: DCC mediated attractive signaling See in Reactome R-HSA-437239 R-HSA-437239 Reactome Name: Recycling pathway of L1 See in Reactome R-HSA-418592 R-HSA-418592 Reactome Name: ADP signalling through P2Y purinoceptor 1 See in Reactome R-HSA-430116 R-HSA-430116 Reactome Name: GP1b-IX-V activation signalling See in Reactome R-HSA-5663220 R-HSA-5663220 Reactome Name: RHO GTPases Activate Formins See in Reactome R-HSA-186763 R-HSA-186763 Reactome Name: Downstream signal transduction See in Reactome R-HSA-180292 R-HSA-180292 Reactome Name: GAB1 signalosome See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-3928662 R-HSA-3928662 Reactome Name: EPHB-mediated forward signaling See in Reactome R-HSA-418555 R-HSA-418555 Reactome Name: G alpha (s) signalling events See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-9032500 R-HSA-9032500 Reactome Name: Activated NTRK2 signals through FYN See in Reactome R-HSA-1257604 R-HSA-1257604 Reactome Name: PIP3 activates AKT signaling See in Reactome R-HSA-389513 R-HSA-389513 Reactome Name: CTLA4 inhibitory signaling See in Reactome R-HSA-8934903 R-HSA-8934903 Reactome Name: Receptor Mediated Mitophagy See in Reactome R-HSA-8853659 R-HSA-8853659 Reactome Name: RET signaling See in Reactome R-HSA-372708 R-HSA-372708 Reactome Name: p130Cas linkage to MAPK signaling for integrins See in Reactome R-HSA-389356 R-HSA-389356 Reactome Name: CD28 co-stimulation See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-391160 R-HSA-391160 Reactome Name: Signal regulatory protein family interactions See in Reactome R-HSA-4420097 R-HSA-4420097 Reactome Name: VEGFA-VEGFR2 Pathway See in Reactome R-HSA-1433559 R-HSA-1433559 Reactome Name: Regulation of KIT signaling See in Reactome R-HSA-2029481 R-HSA-2029481 Reactome Name: FCGR activation See in Reactome R-HSA-1295596 R-HSA-1295596 Reactome Name: Spry regulation of FGF signaling See in Reactome R-HSA-8934593 R-HSA-8934593 Reactome Name: Regulation of RUNX1 Expression and Activity See in Reactome R-HSA-1433557 R-HSA-1433557 Reactome Name: Signaling by SCF-KIT See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-375165 R-HSA-375165 Reactome Name: NCAM signaling for neurite out-growth See in Reactome R-HSA-5607764 R-HSA-5607764 Reactome Name: CLEC7A (Dectin-1) signaling See in Reactome R-HSA-5674135 R-HSA-5674135 Reactome Name: MAP2K and MAPK activation See in Reactome R-HSA-8874081 R-HSA-8874081 Reactome Name: MET activates PTK2 signaling See in Reactome R-HSA-1253288 R-HSA-1253288 Reactome Name: Downregulation of ERBB4 signaling See in Reactome R-HSA-2682334 R-HSA-2682334 Reactome Name: EPH-Ephrin signaling See in Reactome R-HSA-9009391 R-HSA-9009391 Reactome Name: Extra-nuclear estrogen signaling See in Reactome R-HSA-177929 R-HSA-177929 Reactome Name: Signaling by EGFR See in Reactome R-HSA-1251985 R-HSA-1251985 Reactome Name: Nuclear signaling by ERBB4 See in Reactome R-HSA-9603381 R-HSA-9603381 Reactome Name: Activated NTRK3 signals through PI3K See in Reactome R-HSA-354194 R-HSA-354194 Reactome Name: GRB2:SOS provides linkage to MAPK signaling for Integrins See in Reactome R-HSA-3928664 R-HSA-3928664 Reactome Name: Ephrin signaling See in Reactome R-HSA-456926 R-HSA-456926 Reactome Name: Thrombin signalling through proteinase activated receptors (PARs) See in Reactome R-HSA-354192 R-HSA-354192 Reactome Name: Integrin signaling See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-3928665 R-HSA-3928665 Reactome Name: EPH-ephrin mediated repulsion of cells See in Reactome R-HSA-191650 R-HSA-191650 Reactome Name: Regulation of gap junction activity See in Reactome R-HSA-9013420 R-HSA-9013420 Reactome Name: RHOU GTPase cycle See in Reactome R-HSA-6811558 R-HSA-6811558 Reactome Name: PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling See in Reactome R-HSA-210990 R-HSA-210990 Reactome Name: PECAM1 interactions See in Reactome R-HSA-1227986 R-HSA-1227986 Reactome Name: Signaling by ERBB2 See in Reactome R-HSA-5218921 R-HSA-5218921 Reactome Name: VEGFR2 mediated cell proliferation See in Reactome R-HSA-3928663 R-HSA-3928663 Reactome Name: EPHA-mediated growth cone collapse See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-376176 R-HSA-376176 Reactome Name: Signaling by ROBO receptors See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-8941326 R-HSA-8941326 Reactome Name: RUNX2 regulates bone development See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-202733 R-HSA-202733 Reactome Name: Cell surface interactions at the vascular wall See in Reactome R-HSA-1500931 R-HSA-1500931 Reactome Name: Cell-Cell communication See in Reactome R-HSA-195258 R-HSA-195258 Reactome Name: RHO GTPase Effectors See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-373760 R-HSA-373760 Reactome Name: L1CAM interactions See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome R-HSA-76009 R-HSA-76009 Reactome Name: Platelet Aggregation (Plug Formation) See in Reactome R-HSA-9612973 R-HSA-9612973 Reactome Name: Autophagy See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome R-HSA-388841 R-HSA-388841 Reactome Name: Costimulation by the CD28 family See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-5654726 R-HSA-5654726 Reactome Name: Negative regulation of FGFR1 signaling See in Reactome R-HSA-5654727 R-HSA-5654727 Reactome Name: Negative regulation of FGFR2 signaling See in Reactome R-HSA-199418 R-HSA-199418 Reactome Name: Negative regulation of the PI3K/AKT network See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-5205647 R-HSA-5205647 Reactome Name: Mitophagy See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-8875878 R-HSA-8875878 Reactome Name: MET promotes cell motility See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5654743 R-HSA-5654743 Reactome Name: Signaling by FGFR4 See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-190236 R-HSA-190236 Reactome Name: Signaling by FGFR See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-9663891 R-HSA-9663891 Reactome Name: Selective autophagy See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-392518 R-HSA-392518 Reactome Name: Signal amplification See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-157858 R-HSA-157858 Reactome Name: Gap junction trafficking and regulation See in Reactome R-HSA-9006115 R-HSA-9006115 Reactome Name: Signaling by NTRK2 (TRKB) See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-1236394 R-HSA-1236394 Reactome Name: Signaling by ERBB4 See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome R-HSA-1632852 R-HSA-1632852 Reactome Name: Macroautophagy See in Reactome R-HSA-6806834 R-HSA-6806834 Reactome Name: Signaling by MET See in Reactome R-HSA-187687 R-HSA-187687 Reactome Name: Signalling to ERKs See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-5654738 R-HSA-5654738 Reactome Name: Signaling by FGFR2 See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5654736 R-HSA-5654736 Reactome Name: Signaling by FGFR1 See in Reactome R-HSA-5654733 R-HSA-5654733 Reactome Name: Negative regulation of FGFR4 signaling See in Reactome R-HSA-5654732 R-HSA-5654732 Reactome Name: Negative regulation of FGFR3 signaling See in Reactome R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-9034015 R-HSA-9034015 Reactome Name: Signaling by NTRK3 (TRKC) See in Reactome R-HSA-186797 R-HSA-186797 Reactome Name: Signaling by PDGF See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-5654741 R-HSA-5654741 Reactome Name: Signaling by FGFR3 See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-167044 R-HSA-167044 Reactome Name: Signalling to RAS See in Reactome R-HSA-373752 R-HSA-373752 Reactome Name: Netrin-1 signaling See in Reactome	Immune System Cell-Cell communication Cell Cycle Developmental Biology Autophagy Gene expression (Transcription) Neuronal System Signal Transduction Vesicle-mediated transport Hemostasis	R-HSA-1252013 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1252013 Reaction Name: Translocation of ERBB4s80 to the nucleus See in Reactome R-HSA-177923 ( R-HSA-177929; R-HSA-180292 ) R-HSA-177923 Reaction Name: Sustained activation of SRC kinase by SHP2 See in Reactome R-HSA-186819 ( R-HSA-186763 ) R-HSA-186819 Reaction Name: SH2 domain of Src binds to the active receptor See in Reactome R-HSA-1963586 ( R-HSA-1227986 ) R-HSA-1963586 Reaction Name: SRC family kinases phosphorylate ERBB2 See in Reactome R-HSA-2316434 ( R-HSA-1257604; R-HSA-6811558 ) R-HSA-2316434 Reaction Name: PI3K phosphorylates PIP2 to PIP3 See in Reactome R-HSA-354066 ( R-HSA-354192 ) R-HSA-354066 Reaction Name: Translocation of PTK2 to Focal complexes See in Reactome R-HSA-354073 ( R-HSA-354192 ) R-HSA-354073 Reaction Name: Autophosphorylation of PTK2 at Y397 See in Reactome R-HSA-354077 ( R-HSA-354192 ) R-HSA-354077 Reaction Name: Integrin alphaIIb beta3 activation See in Reactome R-HSA-354087 ( R-HSA-354192; R-HSA-354194 ) R-HSA-354087 Reaction Name: Recruitment of GRB2 to p-PTK2 See in Reactome R-HSA-354124 ( R-HSA-354192 ) R-HSA-354124 Reaction Name: Phosphorylation of pPTK2 by SRC See in Reactome R-HSA-354149 ( R-HSA-354192 ) R-HSA-354149 Reaction Name: Interaction of integrin alphaIIb beta3 with Fibrinogen See in Reactome R-HSA-354165 ( R-HSA-354192; R-HSA-354194 ) R-HSA-354165 Reaction Name: Interaction of SOS with GRB2 bound to FADK1 See in Reactome R-HSA-372693 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372693 Reaction Name: Phosphorylation of BCAR1 by SRC-PTK2 complex See in Reactome R-HSA-372697 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372697 Reaction Name: Crk binding to p130cas See in Reactome R-HSA-372705 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372705 Reaction Name: Recruitment of BCAR1 to PTK2 complex See in Reactome R-HSA-373716 ( R-HSA-418885 ) R-HSA-373716 Reaction Name: DCC interacting NCK-1 See in Reactome R-HSA-374701 ( R-HSA-418885 ) R-HSA-374701 Reaction Name: Phosphorylation of DCC by Fyn See in Reactome R-HSA-377640 ( R-HSA-354192 ) R-HSA-377640 Reaction Name: Autophosphorylation of SRC See in Reactome R-HSA-377641 ( R-HSA-354192 ) R-HSA-377641 Reaction Name: Clustering of Integrin alphaIIb beta3 complexes See in Reactome R-HSA-377643 ( R-HSA-354192 ) R-HSA-377643 Reaction Name: Dephosphorylation of inactive SRC by PTPB1 See in Reactome R-HSA-377644 ( R-HSA-354192 ) R-HSA-377644 Reaction Name: Release of CSK from SRC See in Reactome R-HSA-380780 ( R-HSA-186763 ) R-HSA-380780 Reaction Name: Activation of Src See in Reactome R-HSA-418850 ( R-HSA-418885 ) R-HSA-418850 Reaction Name: Activation of Cdc42 See in Reactome R-HSA-418856 ( R-HSA-418885 ) R-HSA-418856 Reaction Name: Activation of Rac1 See in Reactome R-HSA-418858 ( R-HSA-418885 ) R-HSA-418858 Reaction Name: RhoGTPase GEF's recruited to DCC See in Reactome R-HSA-418859 ( R-HSA-418886 ) R-HSA-418859 Reaction Name: Phosphorylation of Unc5C See in Reactome R-HSA-418865 ( R-HSA-418885 ) R-HSA-418865 Reaction Name: Recruitment of ABLIM to the plasma membrane See in Reactome R-HSA-418868 ( R-HSA-418885 ) R-HSA-418868 Reaction Name: Recruitment of Src and Fyn to DCC:FADK1 See in Reactome R-HSA-418874 ( R-HSA-418885 ) R-HSA-418874 Reaction Name: Recruitment and activation of N-WASP by Cdc42 See in Reactome R-HSA-429415 ( R-HSA-354192 ) R-HSA-429415 Reaction Name: SYK binds to integrin alphaIIb beta3 See in Reactome R-HSA-429441 ( R-HSA-354192 ) R-HSA-429441 Reaction Name: SYK activation by SRC See in Reactome R-HSA-432096 ( R-HSA-354192 ) R-HSA-432096 Reaction Name: Activated integrin alphaIIb beta3 binds SHC1 See in Reactome R-HSA-443905 ( R-HSA-354192 ) R-HSA-443905 Reaction Name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow See in Reactome R-HSA-443910 ( R-HSA-354192 ) R-HSA-443910 Reaction Name: SHC1 dissociates from integrin alphaIIb beta3 See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-5672972 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672972 Reaction Name: MAP2Ks and MAPKs bind to the activated RAF complex See in Reactome R-HSA-5672973 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672973 Reaction Name: MAP2Ks phosphorylate MAPKs See in Reactome R-HSA-5672978 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672978 Reaction Name: RAF phosphorylates MAP2K dimer See in Reactome R-HSA-5672980 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672980 Reaction Name: Dissociation of RAS:RAF complex See in Reactome R-HSA-8874080 ( R-HSA-8874081 ) R-HSA-8874080 Reaction Name: SRC phosphorylates PTK2 See in Reactome R-HSA-8874082 ( R-HSA-8874081 ) R-HSA-8874082 Reaction Name: MET phosphorylates PTK2 See in Reactome R-HSA-8874083 ( R-HSA-8874081 ) R-HSA-8874083 Reaction Name: p-Y397-PTK2 binds SRC See in Reactome R-HSA-8937682 ( R-HSA-8934593 ) R-HSA-8937682 Reaction Name: RUNX1 binds SRC See in Reactome R-HSA-8937728 ( R-HSA-8934593 ) R-HSA-8937728 Reaction Name: SRC phosphorylates RUNX1 See in Reactome R-HSA-8937792 ( R-HSA-8941858 ) R-HSA-8937792 Reaction Name: RUNX3 binds SRC See in Reactome R-HSA-8937807 ( R-HSA-8941858 ) R-HSA-8937807 Reaction Name: SRC phosphorylates RUNX3 See in Reactome R-HSA-8937814 ( R-HSA-8941858 ) R-HSA-8937814 Reaction Name: RUNX3 translocates to the nucleus See in Reactome R-HSA-8937820 ( R-HSA-8940973 ) R-HSA-8937820 Reaction Name: SRC,YES1 bind YAP1 See in Reactome R-HSA-8937844 ( R-HSA-8940973 ) R-HSA-8937844 Reaction Name: SRC,YES1 phosphorylate YAP1 See in Reactome R-HSA-8964242 ( R-HSA-418594 ) R-HSA-8964242 Reaction Name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC See in Reactome R-HSA-8964252 ( R-HSA-418555 ) R-HSA-8964252 Reaction Name: G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC See in Reactome R-HSA-8964278 ( R-HSA-418555 ) R-HSA-8964278 Reaction Name: G protein alpha (s):GTP binds SRC See in Reactome R-HSA-8964287 ( R-HSA-418555 ) R-HSA-8964287 Reaction Name: G alpha (s):GTP:SRC dissociates See in Reactome R-HSA-8964311 ( R-HSA-418594 ) R-HSA-8964311 Reaction Name: G alpha (i):GTP binds SRC See in Reactome R-HSA-8964329 ( R-HSA-418594 ) R-HSA-8964329 Reaction Name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC See in Reactome R-HSA-9011241 ( R-HSA-428542 ) R-HSA-9011241 Reaction Name: SRC phosphorylates ROBO3.1 in response to NTN1 See in Reactome R-HSA-9021596 ( R-HSA-9009391 ) R-HSA-9021596 Reaction Name: Membrane estrogen receptors bind SRC See in Reactome R-HSA-9021609 ( R-HSA-9009391 ) R-HSA-9021609 Reaction Name: ESR-associated SRC autophosphorylates See in Reactome R-HSA-9021660 ( R-HSA-9009391 ) R-HSA-9021660 Reaction Name: PI3K binds membrane-associated estrogen receptors See in Reactome R-HSA-9037040 ( R-HSA-9032500 ) R-HSA-9037040 Reaction Name: SRC,FYN phosphorylate NTRK2 See in Reactome R-HSA-9603419 ( R-HSA-9603381 ) R-HSA-9603419 Reaction Name: Activated NTRK3 binds SRC See in Reactome R-HSA-9603420 ( R-HSA-9603381 ) R-HSA-9603420 Reaction Name: Activated NTRK3 promotes SRC autophosphorylation See in Reactome R-HSA-9603437 ( R-HSA-9603381 ) R-HSA-9603437 Reaction Name: Activated NTRK3 binds IRS1 See in Reactome R-HSA-9603445 ( R-HSA-9603381 ) R-HSA-9603445 Reaction Name: Activated NTRK3 stimulates PI3K activity See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9612219 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-9612219 Reaction Name: ERBB4s80 binds to SRC See in Reactome R-HSA-9624014 ( R-HSA-418555 ) R-HSA-9624014 Reaction Name: SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 See in Reactome R-HSA-9632412 ( R-HSA-9009391 ) R-HSA-9632412 Reaction Name: PTK2 is recruited to methylated ESR1 See in Reactome R-HSA-9657599 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657599 Reaction Name: Dual mechanism MAP2K inhibitors bind MAP2Ks See in Reactome R-HSA-9657603 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657603 Reaction Name: Dual mechanism MAPK inhibitors bind MAPKs See in Reactome R-HSA-9657606 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657606 Reaction Name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks See in Reactome R-HSA-9657608 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657608 Reaction Name: Single mechanism MAPK inhibitors bind phosphorylated MAPK See in Reactome R-HSA-9726848 ( R-HSA-9013420 ) R-HSA-9726848 Reaction Name: SRC phosphorylates RHOU See in Reactome
MONDO:0005575	SRC	P12931	2.7.10.2	R-HSA-418886 R-HSA-418886 Reactome Name: Netrin mediated repulsion signals See in Reactome R-HSA-171007 R-HSA-171007 Reactome Name: p38MAPK events See in Reactome R-HSA-428542 R-HSA-428542 Reactome Name: Regulation of commissural axon pathfinding by SLIT and ROBO See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-8940973 R-HSA-8940973 Reactome Name: RUNX2 regulates osteoblast differentiation See in Reactome R-HSA-418885 R-HSA-418885 Reactome Name: DCC mediated attractive signaling See in Reactome R-HSA-437239 R-HSA-437239 Reactome Name: Recycling pathway of L1 See in Reactome R-HSA-418592 R-HSA-418592 Reactome Name: ADP signalling through P2Y purinoceptor 1 See in Reactome R-HSA-430116 R-HSA-430116 Reactome Name: GP1b-IX-V activation signalling See in Reactome R-HSA-5663220 R-HSA-5663220 Reactome Name: RHO GTPases Activate Formins See in Reactome R-HSA-186763 R-HSA-186763 Reactome Name: Downstream signal transduction See in Reactome R-HSA-180292 R-HSA-180292 Reactome Name: GAB1 signalosome See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-3928662 R-HSA-3928662 Reactome Name: EPHB-mediated forward signaling See in Reactome R-HSA-418555 R-HSA-418555 Reactome Name: G alpha (s) signalling events See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-9032500 R-HSA-9032500 Reactome Name: Activated NTRK2 signals through FYN See in Reactome R-HSA-1257604 R-HSA-1257604 Reactome Name: PIP3 activates AKT signaling See in Reactome R-HSA-389513 R-HSA-389513 Reactome Name: CTLA4 inhibitory signaling See in Reactome R-HSA-8934903 R-HSA-8934903 Reactome Name: Receptor Mediated Mitophagy See in Reactome R-HSA-8853659 R-HSA-8853659 Reactome Name: RET signaling See in Reactome R-HSA-372708 R-HSA-372708 Reactome Name: p130Cas linkage to MAPK signaling for integrins See in Reactome R-HSA-389356 R-HSA-389356 Reactome Name: CD28 co-stimulation See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-391160 R-HSA-391160 Reactome Name: Signal regulatory protein family interactions See in Reactome R-HSA-4420097 R-HSA-4420097 Reactome Name: VEGFA-VEGFR2 Pathway See in Reactome R-HSA-1433559 R-HSA-1433559 Reactome Name: Regulation of KIT signaling See in Reactome R-HSA-2029481 R-HSA-2029481 Reactome Name: FCGR activation See in Reactome R-HSA-1295596 R-HSA-1295596 Reactome Name: Spry regulation of FGF signaling See in Reactome R-HSA-8934593 R-HSA-8934593 Reactome Name: Regulation of RUNX1 Expression and Activity See in Reactome R-HSA-1433557 R-HSA-1433557 Reactome Name: Signaling by SCF-KIT See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-375165 R-HSA-375165 Reactome Name: NCAM signaling for neurite out-growth See in Reactome R-HSA-5607764 R-HSA-5607764 Reactome Name: CLEC7A (Dectin-1) signaling See in Reactome R-HSA-5674135 R-HSA-5674135 Reactome Name: MAP2K and MAPK activation See in Reactome R-HSA-8874081 R-HSA-8874081 Reactome Name: MET activates PTK2 signaling See in Reactome R-HSA-1253288 R-HSA-1253288 Reactome Name: Downregulation of ERBB4 signaling See in Reactome R-HSA-2682334 R-HSA-2682334 Reactome Name: EPH-Ephrin signaling See in Reactome R-HSA-9009391 R-HSA-9009391 Reactome Name: Extra-nuclear estrogen signaling See in Reactome R-HSA-177929 R-HSA-177929 Reactome Name: Signaling by EGFR See in Reactome R-HSA-1251985 R-HSA-1251985 Reactome Name: Nuclear signaling by ERBB4 See in Reactome R-HSA-9603381 R-HSA-9603381 Reactome Name: Activated NTRK3 signals through PI3K See in Reactome R-HSA-354194 R-HSA-354194 Reactome Name: GRB2:SOS provides linkage to MAPK signaling for Integrins See in Reactome R-HSA-3928664 R-HSA-3928664 Reactome Name: Ephrin signaling See in Reactome R-HSA-456926 R-HSA-456926 Reactome Name: Thrombin signalling through proteinase activated receptors (PARs) See in Reactome R-HSA-354192 R-HSA-354192 Reactome Name: Integrin signaling See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-3928665 R-HSA-3928665 Reactome Name: EPH-ephrin mediated repulsion of cells See in Reactome R-HSA-191650 R-HSA-191650 Reactome Name: Regulation of gap junction activity See in Reactome R-HSA-9013420 R-HSA-9013420 Reactome Name: RHOU GTPase cycle See in Reactome R-HSA-6811558 R-HSA-6811558 Reactome Name: PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling See in Reactome R-HSA-210990 R-HSA-210990 Reactome Name: PECAM1 interactions See in Reactome R-HSA-1227986 R-HSA-1227986 Reactome Name: Signaling by ERBB2 See in Reactome R-HSA-5218921 R-HSA-5218921 Reactome Name: VEGFR2 mediated cell proliferation See in Reactome R-HSA-3928663 R-HSA-3928663 Reactome Name: EPHA-mediated growth cone collapse See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-376176 R-HSA-376176 Reactome Name: Signaling by ROBO receptors See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-8941326 R-HSA-8941326 Reactome Name: RUNX2 regulates bone development See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-202733 R-HSA-202733 Reactome Name: Cell surface interactions at the vascular wall See in Reactome R-HSA-1500931 R-HSA-1500931 Reactome Name: Cell-Cell communication See in Reactome R-HSA-195258 R-HSA-195258 Reactome Name: RHO GTPase Effectors See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-373760 R-HSA-373760 Reactome Name: L1CAM interactions See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome R-HSA-76009 R-HSA-76009 Reactome Name: Platelet Aggregation (Plug Formation) See in Reactome R-HSA-9612973 R-HSA-9612973 Reactome Name: Autophagy See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome R-HSA-388841 R-HSA-388841 Reactome Name: Costimulation by the CD28 family See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-5654726 R-HSA-5654726 Reactome Name: Negative regulation of FGFR1 signaling See in Reactome R-HSA-5654727 R-HSA-5654727 Reactome Name: Negative regulation of FGFR2 signaling See in Reactome R-HSA-199418 R-HSA-199418 Reactome Name: Negative regulation of the PI3K/AKT network See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-5205647 R-HSA-5205647 Reactome Name: Mitophagy See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-8875878 R-HSA-8875878 Reactome Name: MET promotes cell motility See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5654743 R-HSA-5654743 Reactome Name: Signaling by FGFR4 See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-190236 R-HSA-190236 Reactome Name: Signaling by FGFR See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-9663891 R-HSA-9663891 Reactome Name: Selective autophagy See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-392518 R-HSA-392518 Reactome Name: Signal amplification See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-157858 R-HSA-157858 Reactome Name: Gap junction trafficking and regulation See in Reactome R-HSA-9006115 R-HSA-9006115 Reactome Name: Signaling by NTRK2 (TRKB) See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-1236394 R-HSA-1236394 Reactome Name: Signaling by ERBB4 See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome R-HSA-1632852 R-HSA-1632852 Reactome Name: Macroautophagy See in Reactome R-HSA-6806834 R-HSA-6806834 Reactome Name: Signaling by MET See in Reactome R-HSA-187687 R-HSA-187687 Reactome Name: Signalling to ERKs See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-5654738 R-HSA-5654738 Reactome Name: Signaling by FGFR2 See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5654736 R-HSA-5654736 Reactome Name: Signaling by FGFR1 See in Reactome R-HSA-5654733 R-HSA-5654733 Reactome Name: Negative regulation of FGFR4 signaling See in Reactome R-HSA-5654732 R-HSA-5654732 Reactome Name: Negative regulation of FGFR3 signaling See in Reactome R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-9034015 R-HSA-9034015 Reactome Name: Signaling by NTRK3 (TRKC) See in Reactome R-HSA-186797 R-HSA-186797 Reactome Name: Signaling by PDGF See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-5654741 R-HSA-5654741 Reactome Name: Signaling by FGFR3 See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-167044 R-HSA-167044 Reactome Name: Signalling to RAS See in Reactome R-HSA-373752 R-HSA-373752 Reactome Name: Netrin-1 signaling See in Reactome	Immune System Cell-Cell communication Cell Cycle Developmental Biology Autophagy Gene expression (Transcription) Neuronal System Signal Transduction Vesicle-mediated transport Hemostasis	R-HSA-1252013 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1252013 Reaction Name: Translocation of ERBB4s80 to the nucleus See in Reactome R-HSA-177923 ( R-HSA-177929; R-HSA-180292 ) R-HSA-177923 Reaction Name: Sustained activation of SRC kinase by SHP2 See in Reactome R-HSA-186819 ( R-HSA-186763 ) R-HSA-186819 Reaction Name: SH2 domain of Src binds to the active receptor See in Reactome R-HSA-1963586 ( R-HSA-1227986 ) R-HSA-1963586 Reaction Name: SRC family kinases phosphorylate ERBB2 See in Reactome R-HSA-2316434 ( R-HSA-1257604; R-HSA-6811558 ) R-HSA-2316434 Reaction Name: PI3K phosphorylates PIP2 to PIP3 See in Reactome R-HSA-354066 ( R-HSA-354192 ) R-HSA-354066 Reaction Name: Translocation of PTK2 to Focal complexes See in Reactome R-HSA-354073 ( R-HSA-354192 ) R-HSA-354073 Reaction Name: Autophosphorylation of PTK2 at Y397 See in Reactome R-HSA-354077 ( R-HSA-354192 ) R-HSA-354077 Reaction Name: Integrin alphaIIb beta3 activation See in Reactome R-HSA-354087 ( R-HSA-354192; R-HSA-354194 ) R-HSA-354087 Reaction Name: Recruitment of GRB2 to p-PTK2 See in Reactome R-HSA-354124 ( R-HSA-354192 ) R-HSA-354124 Reaction Name: Phosphorylation of pPTK2 by SRC See in Reactome R-HSA-354149 ( R-HSA-354192 ) R-HSA-354149 Reaction Name: Interaction of integrin alphaIIb beta3 with Fibrinogen See in Reactome R-HSA-354165 ( R-HSA-354192; R-HSA-354194 ) R-HSA-354165 Reaction Name: Interaction of SOS with GRB2 bound to FADK1 See in Reactome R-HSA-372693 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372693 Reaction Name: Phosphorylation of BCAR1 by SRC-PTK2 complex See in Reactome R-HSA-372697 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372697 Reaction Name: Crk binding to p130cas See in Reactome R-HSA-372705 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372705 Reaction Name: Recruitment of BCAR1 to PTK2 complex See in Reactome R-HSA-373716 ( R-HSA-418885 ) R-HSA-373716 Reaction Name: DCC interacting NCK-1 See in Reactome R-HSA-374701 ( R-HSA-418885 ) R-HSA-374701 Reaction Name: Phosphorylation of DCC by Fyn See in Reactome R-HSA-377640 ( R-HSA-354192 ) R-HSA-377640 Reaction Name: Autophosphorylation of SRC See in Reactome R-HSA-377641 ( R-HSA-354192 ) R-HSA-377641 Reaction Name: Clustering of Integrin alphaIIb beta3 complexes See in Reactome R-HSA-377643 ( R-HSA-354192 ) R-HSA-377643 Reaction Name: Dephosphorylation of inactive SRC by PTPB1 See in Reactome R-HSA-377644 ( R-HSA-354192 ) R-HSA-377644 Reaction Name: Release of CSK from SRC See in Reactome R-HSA-380780 ( R-HSA-186763 ) R-HSA-380780 Reaction Name: Activation of Src See in Reactome R-HSA-418850 ( R-HSA-418885 ) R-HSA-418850 Reaction Name: Activation of Cdc42 See in Reactome R-HSA-418856 ( R-HSA-418885 ) R-HSA-418856 Reaction Name: Activation of Rac1 See in Reactome R-HSA-418858 ( R-HSA-418885 ) R-HSA-418858 Reaction Name: RhoGTPase GEF's recruited to DCC See in Reactome R-HSA-418859 ( R-HSA-418886 ) R-HSA-418859 Reaction Name: Phosphorylation of Unc5C See in Reactome R-HSA-418865 ( R-HSA-418885 ) R-HSA-418865 Reaction Name: Recruitment of ABLIM to the plasma membrane See in Reactome R-HSA-418868 ( R-HSA-418885 ) R-HSA-418868 Reaction Name: Recruitment of Src and Fyn to DCC:FADK1 See in Reactome R-HSA-418874 ( R-HSA-418885 ) R-HSA-418874 Reaction Name: Recruitment and activation of N-WASP by Cdc42 See in Reactome R-HSA-429415 ( R-HSA-354192 ) R-HSA-429415 Reaction Name: SYK binds to integrin alphaIIb beta3 See in Reactome R-HSA-429441 ( R-HSA-354192 ) R-HSA-429441 Reaction Name: SYK activation by SRC See in Reactome R-HSA-432096 ( R-HSA-354192 ) R-HSA-432096 Reaction Name: Activated integrin alphaIIb beta3 binds SHC1 See in Reactome R-HSA-443905 ( R-HSA-354192 ) R-HSA-443905 Reaction Name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow See in Reactome R-HSA-443910 ( R-HSA-354192 ) R-HSA-443910 Reaction Name: SHC1 dissociates from integrin alphaIIb beta3 See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-5672972 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672972 Reaction Name: MAP2Ks and MAPKs bind to the activated RAF complex See in Reactome R-HSA-5672973 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672973 Reaction Name: MAP2Ks phosphorylate MAPKs See in Reactome R-HSA-5672978 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672978 Reaction Name: RAF phosphorylates MAP2K dimer See in Reactome R-HSA-5672980 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672980 Reaction Name: Dissociation of RAS:RAF complex See in Reactome R-HSA-8874080 ( R-HSA-8874081 ) R-HSA-8874080 Reaction Name: SRC phosphorylates PTK2 See in Reactome R-HSA-8874082 ( R-HSA-8874081 ) R-HSA-8874082 Reaction Name: MET phosphorylates PTK2 See in Reactome R-HSA-8874083 ( R-HSA-8874081 ) R-HSA-8874083 Reaction Name: p-Y397-PTK2 binds SRC See in Reactome R-HSA-8937682 ( R-HSA-8934593 ) R-HSA-8937682 Reaction Name: RUNX1 binds SRC See in Reactome R-HSA-8937728 ( R-HSA-8934593 ) R-HSA-8937728 Reaction Name: SRC phosphorylates RUNX1 See in Reactome R-HSA-8937792 ( R-HSA-8941858 ) R-HSA-8937792 Reaction Name: RUNX3 binds SRC See in Reactome R-HSA-8937807 ( R-HSA-8941858 ) R-HSA-8937807 Reaction Name: SRC phosphorylates RUNX3 See in Reactome R-HSA-8937814 ( R-HSA-8941858 ) R-HSA-8937814 Reaction Name: RUNX3 translocates to the nucleus See in Reactome R-HSA-8937820 ( R-HSA-8940973 ) R-HSA-8937820 Reaction Name: SRC,YES1 bind YAP1 See in Reactome R-HSA-8937844 ( R-HSA-8940973 ) R-HSA-8937844 Reaction Name: SRC,YES1 phosphorylate YAP1 See in Reactome R-HSA-8964242 ( R-HSA-418594 ) R-HSA-8964242 Reaction Name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC See in Reactome R-HSA-8964252 ( R-HSA-418555 ) R-HSA-8964252 Reaction Name: G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC See in Reactome R-HSA-8964278 ( R-HSA-418555 ) R-HSA-8964278 Reaction Name: G protein alpha (s):GTP binds SRC See in Reactome R-HSA-8964287 ( R-HSA-418555 ) R-HSA-8964287 Reaction Name: G alpha (s):GTP:SRC dissociates See in Reactome R-HSA-8964311 ( R-HSA-418594 ) R-HSA-8964311 Reaction Name: G alpha (i):GTP binds SRC See in Reactome R-HSA-8964329 ( R-HSA-418594 ) R-HSA-8964329 Reaction Name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC See in Reactome R-HSA-9011241 ( R-HSA-428542 ) R-HSA-9011241 Reaction Name: SRC phosphorylates ROBO3.1 in response to NTN1 See in Reactome R-HSA-9021596 ( R-HSA-9009391 ) R-HSA-9021596 Reaction Name: Membrane estrogen receptors bind SRC See in Reactome R-HSA-9021609 ( R-HSA-9009391 ) R-HSA-9021609 Reaction Name: ESR-associated SRC autophosphorylates See in Reactome R-HSA-9021660 ( R-HSA-9009391 ) R-HSA-9021660 Reaction Name: PI3K binds membrane-associated estrogen receptors See in Reactome R-HSA-9037040 ( R-HSA-9032500 ) R-HSA-9037040 Reaction Name: SRC,FYN phosphorylate NTRK2 See in Reactome R-HSA-9603419 ( R-HSA-9603381 ) R-HSA-9603419 Reaction Name: Activated NTRK3 binds SRC See in Reactome R-HSA-9603420 ( R-HSA-9603381 ) R-HSA-9603420 Reaction Name: Activated NTRK3 promotes SRC autophosphorylation See in Reactome R-HSA-9603437 ( R-HSA-9603381 ) R-HSA-9603437 Reaction Name: Activated NTRK3 binds IRS1 See in Reactome R-HSA-9603445 ( R-HSA-9603381 ) R-HSA-9603445 Reaction Name: Activated NTRK3 stimulates PI3K activity See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9612219 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-9612219 Reaction Name: ERBB4s80 binds to SRC See in Reactome R-HSA-9624014 ( R-HSA-418555 ) R-HSA-9624014 Reaction Name: SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 See in Reactome R-HSA-9632412 ( R-HSA-9009391 ) R-HSA-9632412 Reaction Name: PTK2 is recruited to methylated ESR1 See in Reactome R-HSA-9657599 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657599 Reaction Name: Dual mechanism MAP2K inhibitors bind MAP2Ks See in Reactome R-HSA-9657603 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657603 Reaction Name: Dual mechanism MAPK inhibitors bind MAPKs See in Reactome R-HSA-9657606 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657606 Reaction Name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks See in Reactome R-HSA-9657608 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657608 Reaction Name: Single mechanism MAPK inhibitors bind phosphorylated MAPK See in Reactome R-HSA-9726848 ( R-HSA-9013420 ) R-HSA-9726848 Reaction Name: SRC phosphorylates RHOU See in Reactome
MONDO:0009692	SRC	P12931	2.7.10.2	R-HSA-418886 R-HSA-418886 Reactome Name: Netrin mediated repulsion signals See in Reactome R-HSA-171007 R-HSA-171007 Reactome Name: p38MAPK events See in Reactome R-HSA-428542 R-HSA-428542 Reactome Name: Regulation of commissural axon pathfinding by SLIT and ROBO See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-8940973 R-HSA-8940973 Reactome Name: RUNX2 regulates osteoblast differentiation See in Reactome R-HSA-418885 R-HSA-418885 Reactome Name: DCC mediated attractive signaling See in Reactome R-HSA-437239 R-HSA-437239 Reactome Name: Recycling pathway of L1 See in Reactome R-HSA-418592 R-HSA-418592 Reactome Name: ADP signalling through P2Y purinoceptor 1 See in Reactome R-HSA-430116 R-HSA-430116 Reactome Name: GP1b-IX-V activation signalling See in Reactome R-HSA-5663220 R-HSA-5663220 Reactome Name: RHO GTPases Activate Formins See in Reactome R-HSA-186763 R-HSA-186763 Reactome Name: Downstream signal transduction See in Reactome R-HSA-180292 R-HSA-180292 Reactome Name: GAB1 signalosome See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-3928662 R-HSA-3928662 Reactome Name: EPHB-mediated forward signaling See in Reactome R-HSA-418555 R-HSA-418555 Reactome Name: G alpha (s) signalling events See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-9032500 R-HSA-9032500 Reactome Name: Activated NTRK2 signals through FYN See in Reactome R-HSA-1257604 R-HSA-1257604 Reactome Name: PIP3 activates AKT signaling See in Reactome R-HSA-389513 R-HSA-389513 Reactome Name: CTLA4 inhibitory signaling See in Reactome R-HSA-8934903 R-HSA-8934903 Reactome Name: Receptor Mediated Mitophagy See in Reactome R-HSA-8853659 R-HSA-8853659 Reactome Name: RET signaling See in Reactome R-HSA-372708 R-HSA-372708 Reactome Name: p130Cas linkage to MAPK signaling for integrins See in Reactome R-HSA-389356 R-HSA-389356 Reactome Name: CD28 co-stimulation See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-391160 R-HSA-391160 Reactome Name: Signal regulatory protein family interactions See in Reactome R-HSA-4420097 R-HSA-4420097 Reactome Name: VEGFA-VEGFR2 Pathway See in Reactome R-HSA-1433559 R-HSA-1433559 Reactome Name: Regulation of KIT signaling See in Reactome R-HSA-2029481 R-HSA-2029481 Reactome Name: FCGR activation See in Reactome R-HSA-1295596 R-HSA-1295596 Reactome Name: Spry regulation of FGF signaling See in Reactome R-HSA-8934593 R-HSA-8934593 Reactome Name: Regulation of RUNX1 Expression and Activity See in Reactome R-HSA-1433557 R-HSA-1433557 Reactome Name: Signaling by SCF-KIT See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-375165 R-HSA-375165 Reactome Name: NCAM signaling for neurite out-growth See in Reactome R-HSA-5607764 R-HSA-5607764 Reactome Name: CLEC7A (Dectin-1) signaling See in Reactome R-HSA-5674135 R-HSA-5674135 Reactome Name: MAP2K and MAPK activation See in Reactome R-HSA-8874081 R-HSA-8874081 Reactome Name: MET activates PTK2 signaling See in Reactome R-HSA-1253288 R-HSA-1253288 Reactome Name: Downregulation of ERBB4 signaling See in Reactome R-HSA-2682334 R-HSA-2682334 Reactome Name: EPH-Ephrin signaling See in Reactome R-HSA-9009391 R-HSA-9009391 Reactome Name: Extra-nuclear estrogen signaling See in Reactome R-HSA-177929 R-HSA-177929 Reactome Name: Signaling by EGFR See in Reactome R-HSA-1251985 R-HSA-1251985 Reactome Name: Nuclear signaling by ERBB4 See in Reactome R-HSA-9603381 R-HSA-9603381 Reactome Name: Activated NTRK3 signals through PI3K See in Reactome R-HSA-354194 R-HSA-354194 Reactome Name: GRB2:SOS provides linkage to MAPK signaling for Integrins See in Reactome R-HSA-3928664 R-HSA-3928664 Reactome Name: Ephrin signaling See in Reactome R-HSA-456926 R-HSA-456926 Reactome Name: Thrombin signalling through proteinase activated receptors (PARs) See in Reactome R-HSA-354192 R-HSA-354192 Reactome Name: Integrin signaling See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-3928665 R-HSA-3928665 Reactome Name: EPH-ephrin mediated repulsion of cells See in Reactome R-HSA-191650 R-HSA-191650 Reactome Name: Regulation of gap junction activity See in Reactome R-HSA-9013420 R-HSA-9013420 Reactome Name: RHOU GTPase cycle See in Reactome R-HSA-6811558 R-HSA-6811558 Reactome Name: PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling See in Reactome R-HSA-210990 R-HSA-210990 Reactome Name: PECAM1 interactions See in Reactome R-HSA-1227986 R-HSA-1227986 Reactome Name: Signaling by ERBB2 See in Reactome R-HSA-5218921 R-HSA-5218921 Reactome Name: VEGFR2 mediated cell proliferation See in Reactome R-HSA-3928663 R-HSA-3928663 Reactome Name: EPHA-mediated growth cone collapse See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-376176 R-HSA-376176 Reactome Name: Signaling by ROBO receptors See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-8941326 R-HSA-8941326 Reactome Name: RUNX2 regulates bone development See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-202733 R-HSA-202733 Reactome Name: Cell surface interactions at the vascular wall See in Reactome R-HSA-1500931 R-HSA-1500931 Reactome Name: Cell-Cell communication See in Reactome R-HSA-195258 R-HSA-195258 Reactome Name: RHO GTPase Effectors See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-373760 R-HSA-373760 Reactome Name: L1CAM interactions See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome R-HSA-76009 R-HSA-76009 Reactome Name: Platelet Aggregation (Plug Formation) See in Reactome R-HSA-9612973 R-HSA-9612973 Reactome Name: Autophagy See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome R-HSA-388841 R-HSA-388841 Reactome Name: Costimulation by the CD28 family See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-5654726 R-HSA-5654726 Reactome Name: Negative regulation of FGFR1 signaling See in Reactome R-HSA-5654727 R-HSA-5654727 Reactome Name: Negative regulation of FGFR2 signaling See in Reactome R-HSA-199418 R-HSA-199418 Reactome Name: Negative regulation of the PI3K/AKT network See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-5205647 R-HSA-5205647 Reactome Name: Mitophagy See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-8875878 R-HSA-8875878 Reactome Name: MET promotes cell motility See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5654743 R-HSA-5654743 Reactome Name: Signaling by FGFR4 See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-190236 R-HSA-190236 Reactome Name: Signaling by FGFR See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-9663891 R-HSA-9663891 Reactome Name: Selective autophagy See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-392518 R-HSA-392518 Reactome Name: Signal amplification See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-157858 R-HSA-157858 Reactome Name: Gap junction trafficking and regulation See in Reactome R-HSA-9006115 R-HSA-9006115 Reactome Name: Signaling by NTRK2 (TRKB) See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-1236394 R-HSA-1236394 Reactome Name: Signaling by ERBB4 See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome R-HSA-1632852 R-HSA-1632852 Reactome Name: Macroautophagy See in Reactome R-HSA-6806834 R-HSA-6806834 Reactome Name: Signaling by MET See in Reactome R-HSA-187687 R-HSA-187687 Reactome Name: Signalling to ERKs See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-5654738 R-HSA-5654738 Reactome Name: Signaling by FGFR2 See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5654736 R-HSA-5654736 Reactome Name: Signaling by FGFR1 See in Reactome R-HSA-5654733 R-HSA-5654733 Reactome Name: Negative regulation of FGFR4 signaling See in Reactome R-HSA-5654732 R-HSA-5654732 Reactome Name: Negative regulation of FGFR3 signaling See in Reactome R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-9034015 R-HSA-9034015 Reactome Name: Signaling by NTRK3 (TRKC) See in Reactome R-HSA-186797 R-HSA-186797 Reactome Name: Signaling by PDGF See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-5654741 R-HSA-5654741 Reactome Name: Signaling by FGFR3 See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-167044 R-HSA-167044 Reactome Name: Signalling to RAS See in Reactome R-HSA-373752 R-HSA-373752 Reactome Name: Netrin-1 signaling See in Reactome	Immune System Cell-Cell communication Cell Cycle Developmental Biology Autophagy Gene expression (Transcription) Neuronal System Signal Transduction Vesicle-mediated transport Hemostasis	R-HSA-1252013 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1252013 Reaction Name: Translocation of ERBB4s80 to the nucleus See in Reactome R-HSA-177923 ( R-HSA-177929; R-HSA-180292 ) R-HSA-177923 Reaction Name: Sustained activation of SRC kinase by SHP2 See in Reactome R-HSA-186819 ( R-HSA-186763 ) R-HSA-186819 Reaction Name: SH2 domain of Src binds to the active receptor See in Reactome R-HSA-1963586 ( R-HSA-1227986 ) R-HSA-1963586 Reaction Name: SRC family kinases phosphorylate ERBB2 See in Reactome R-HSA-2316434 ( R-HSA-1257604; R-HSA-6811558 ) R-HSA-2316434 Reaction Name: PI3K phosphorylates PIP2 to PIP3 See in Reactome R-HSA-354066 ( R-HSA-354192 ) R-HSA-354066 Reaction Name: Translocation of PTK2 to Focal complexes See in Reactome R-HSA-354073 ( R-HSA-354192 ) R-HSA-354073 Reaction Name: Autophosphorylation of PTK2 at Y397 See in Reactome R-HSA-354077 ( R-HSA-354192 ) R-HSA-354077 Reaction Name: Integrin alphaIIb beta3 activation See in Reactome R-HSA-354087 ( R-HSA-354192; R-HSA-354194 ) R-HSA-354087 Reaction Name: Recruitment of GRB2 to p-PTK2 See in Reactome R-HSA-354124 ( R-HSA-354192 ) R-HSA-354124 Reaction Name: Phosphorylation of pPTK2 by SRC See in Reactome R-HSA-354149 ( R-HSA-354192 ) R-HSA-354149 Reaction Name: Interaction of integrin alphaIIb beta3 with Fibrinogen See in Reactome R-HSA-354165 ( R-HSA-354192; R-HSA-354194 ) R-HSA-354165 Reaction Name: Interaction of SOS with GRB2 bound to FADK1 See in Reactome R-HSA-372693 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372693 Reaction Name: Phosphorylation of BCAR1 by SRC-PTK2 complex See in Reactome R-HSA-372697 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372697 Reaction Name: Crk binding to p130cas See in Reactome R-HSA-372705 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372705 Reaction Name: Recruitment of BCAR1 to PTK2 complex See in Reactome R-HSA-373716 ( R-HSA-418885 ) R-HSA-373716 Reaction Name: DCC interacting NCK-1 See in Reactome R-HSA-374701 ( R-HSA-418885 ) R-HSA-374701 Reaction Name: Phosphorylation of DCC by Fyn See in Reactome R-HSA-377640 ( R-HSA-354192 ) R-HSA-377640 Reaction Name: Autophosphorylation of SRC See in Reactome R-HSA-377641 ( R-HSA-354192 ) R-HSA-377641 Reaction Name: Clustering of Integrin alphaIIb beta3 complexes See in Reactome R-HSA-377643 ( R-HSA-354192 ) R-HSA-377643 Reaction Name: Dephosphorylation of inactive SRC by PTPB1 See in Reactome R-HSA-377644 ( R-HSA-354192 ) R-HSA-377644 Reaction Name: Release of CSK from SRC See in Reactome R-HSA-380780 ( R-HSA-186763 ) R-HSA-380780 Reaction Name: Activation of Src See in Reactome R-HSA-418850 ( R-HSA-418885 ) R-HSA-418850 Reaction Name: Activation of Cdc42 See in Reactome R-HSA-418856 ( R-HSA-418885 ) R-HSA-418856 Reaction Name: Activation of Rac1 See in Reactome R-HSA-418858 ( R-HSA-418885 ) R-HSA-418858 Reaction Name: RhoGTPase GEF's recruited to DCC See in Reactome R-HSA-418859 ( R-HSA-418886 ) R-HSA-418859 Reaction Name: Phosphorylation of Unc5C See in Reactome R-HSA-418865 ( R-HSA-418885 ) R-HSA-418865 Reaction Name: Recruitment of ABLIM to the plasma membrane See in Reactome R-HSA-418868 ( R-HSA-418885 ) R-HSA-418868 Reaction Name: Recruitment of Src and Fyn to DCC:FADK1 See in Reactome R-HSA-418874 ( R-HSA-418885 ) R-HSA-418874 Reaction Name: Recruitment and activation of N-WASP by Cdc42 See in Reactome R-HSA-429415 ( R-HSA-354192 ) R-HSA-429415 Reaction Name: SYK binds to integrin alphaIIb beta3 See in Reactome R-HSA-429441 ( R-HSA-354192 ) R-HSA-429441 Reaction Name: SYK activation by SRC See in Reactome R-HSA-432096 ( R-HSA-354192 ) R-HSA-432096 Reaction Name: Activated integrin alphaIIb beta3 binds SHC1 See in Reactome R-HSA-443905 ( R-HSA-354192 ) R-HSA-443905 Reaction Name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow See in Reactome R-HSA-443910 ( R-HSA-354192 ) R-HSA-443910 Reaction Name: SHC1 dissociates from integrin alphaIIb beta3 See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-5672972 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672972 Reaction Name: MAP2Ks and MAPKs bind to the activated RAF complex See in Reactome R-HSA-5672973 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672973 Reaction Name: MAP2Ks phosphorylate MAPKs See in Reactome R-HSA-5672978 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672978 Reaction Name: RAF phosphorylates MAP2K dimer See in Reactome R-HSA-5672980 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672980 Reaction Name: Dissociation of RAS:RAF complex See in Reactome R-HSA-8874080 ( R-HSA-8874081 ) R-HSA-8874080 Reaction Name: SRC phosphorylates PTK2 See in Reactome R-HSA-8874082 ( R-HSA-8874081 ) R-HSA-8874082 Reaction Name: MET phosphorylates PTK2 See in Reactome R-HSA-8874083 ( R-HSA-8874081 ) R-HSA-8874083 Reaction Name: p-Y397-PTK2 binds SRC See in Reactome R-HSA-8937682 ( R-HSA-8934593 ) R-HSA-8937682 Reaction Name: RUNX1 binds SRC See in Reactome R-HSA-8937728 ( R-HSA-8934593 ) R-HSA-8937728 Reaction Name: SRC phosphorylates RUNX1 See in Reactome R-HSA-8937792 ( R-HSA-8941858 ) R-HSA-8937792 Reaction Name: RUNX3 binds SRC See in Reactome R-HSA-8937807 ( R-HSA-8941858 ) R-HSA-8937807 Reaction Name: SRC phosphorylates RUNX3 See in Reactome R-HSA-8937814 ( R-HSA-8941858 ) R-HSA-8937814 Reaction Name: RUNX3 translocates to the nucleus See in Reactome R-HSA-8937820 ( R-HSA-8940973 ) R-HSA-8937820 Reaction Name: SRC,YES1 bind YAP1 See in Reactome R-HSA-8937844 ( R-HSA-8940973 ) R-HSA-8937844 Reaction Name: SRC,YES1 phosphorylate YAP1 See in Reactome R-HSA-8964242 ( R-HSA-418594 ) R-HSA-8964242 Reaction Name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC See in Reactome R-HSA-8964252 ( R-HSA-418555 ) R-HSA-8964252 Reaction Name: G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC See in Reactome R-HSA-8964278 ( R-HSA-418555 ) R-HSA-8964278 Reaction Name: G protein alpha (s):GTP binds SRC See in Reactome R-HSA-8964287 ( R-HSA-418555 ) R-HSA-8964287 Reaction Name: G alpha (s):GTP:SRC dissociates See in Reactome R-HSA-8964311 ( R-HSA-418594 ) R-HSA-8964311 Reaction Name: G alpha (i):GTP binds SRC See in Reactome R-HSA-8964329 ( R-HSA-418594 ) R-HSA-8964329 Reaction Name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC See in Reactome R-HSA-9011241 ( R-HSA-428542 ) R-HSA-9011241 Reaction Name: SRC phosphorylates ROBO3.1 in response to NTN1 See in Reactome R-HSA-9021596 ( R-HSA-9009391 ) R-HSA-9021596 Reaction Name: Membrane estrogen receptors bind SRC See in Reactome R-HSA-9021609 ( R-HSA-9009391 ) R-HSA-9021609 Reaction Name: ESR-associated SRC autophosphorylates See in Reactome R-HSA-9021660 ( R-HSA-9009391 ) R-HSA-9021660 Reaction Name: PI3K binds membrane-associated estrogen receptors See in Reactome R-HSA-9037040 ( R-HSA-9032500 ) R-HSA-9037040 Reaction Name: SRC,FYN phosphorylate NTRK2 See in Reactome R-HSA-9603419 ( R-HSA-9603381 ) R-HSA-9603419 Reaction Name: Activated NTRK3 binds SRC See in Reactome R-HSA-9603420 ( R-HSA-9603381 ) R-HSA-9603420 Reaction Name: Activated NTRK3 promotes SRC autophosphorylation See in Reactome R-HSA-9603437 ( R-HSA-9603381 ) R-HSA-9603437 Reaction Name: Activated NTRK3 binds IRS1 See in Reactome R-HSA-9603445 ( R-HSA-9603381 ) R-HSA-9603445 Reaction Name: Activated NTRK3 stimulates PI3K activity See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9612219 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-9612219 Reaction Name: ERBB4s80 binds to SRC See in Reactome R-HSA-9624014 ( R-HSA-418555 ) R-HSA-9624014 Reaction Name: SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 See in Reactome R-HSA-9632412 ( R-HSA-9009391 ) R-HSA-9632412 Reaction Name: PTK2 is recruited to methylated ESR1 See in Reactome R-HSA-9657599 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657599 Reaction Name: Dual mechanism MAP2K inhibitors bind MAP2Ks See in Reactome R-HSA-9657603 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657603 Reaction Name: Dual mechanism MAPK inhibitors bind MAPKs See in Reactome R-HSA-9657606 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657606 Reaction Name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks See in Reactome R-HSA-9657608 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657608 Reaction Name: Single mechanism MAPK inhibitors bind phosphorylated MAPK See in Reactome R-HSA-9726848 ( R-HSA-9013420 ) R-HSA-9726848 Reaction Name: SRC phosphorylates RHOU See in Reactome
MONDO:0014223	ERBB4	Q15303	2.7.10.1	R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-1963640 R-HSA-1963640 Reactome Name: GRB2 events in ERBB2 signaling See in Reactome R-HSA-1257604 R-HSA-1257604 Reactome Name: PIP3 activates AKT signaling See in Reactome R-HSA-1250347 R-HSA-1250347 Reactome Name: SHC1 events in ERBB4 signaling See in Reactome R-HSA-1250342 R-HSA-1250342 Reactome Name: PI3K events in ERBB4 signaling See in Reactome R-HSA-1963642 R-HSA-1963642 Reactome Name: PI3K events in ERBB2 signaling See in Reactome R-HSA-6785631 R-HSA-6785631 Reactome Name: ERBB2 Regulates Cell Motility See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-6811558 R-HSA-6811558 Reactome Name: PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling See in Reactome R-HSA-1250196 R-HSA-1250196 Reactome Name: SHC1 events in ERBB2 signaling See in Reactome R-HSA-1227986 R-HSA-1227986 Reactome Name: Signaling by ERBB2 See in Reactome R-HSA-1236394 R-HSA-1236394 Reactome Name: Signaling by ERBB4 See in Reactome R-HSA-1253288 R-HSA-1253288 Reactome Name: Downregulation of ERBB4 signaling See in Reactome R-HSA-8847993 R-HSA-8847993 Reactome Name: ERBB2 Activates PTK6 Signaling See in Reactome R-HSA-8863795 R-HSA-8863795 Reactome Name: Downregulation of ERBB2 signaling See in Reactome R-HSA-1251985 R-HSA-1251985 Reactome Name: Nuclear signaling by ERBB4 See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-199418 R-HSA-199418 Reactome Name: Negative regulation of the PI3K/AKT network See in Reactome R-HSA-8848021 R-HSA-8848021 Reactome Name: Signaling by PTK6 See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-9006927 R-HSA-9006927 Reactome Name: Signaling by Non-Receptor Tyrosine Kinases See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Neuronal System Signal Transduction	R-HSA-1236398 ( R-HSA-1236394 ) R-HSA-1236398 Reaction Name: ERBB4 binds NRGs or EGF-like ligands See in Reactome R-HSA-1250195 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1250195 Reaction Name: SHC1 phosphorylation by ERBB2 heterodimers See in Reactome R-HSA-1250220 ( R-HSA-1236394 ) R-HSA-1250220 Reaction Name: Homodimerization of ERBB4 See in Reactome R-HSA-1250315 ( R-HSA-1236394 ) R-HSA-1250315 Reaction Name: Trans-autophosphorylation of ERBB4 homodimers See in Reactome R-HSA-1250346 ( R-HSA-1227986; R-HSA-1963642 ) R-HSA-1250346 Reaction Name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers See in Reactome R-HSA-1250348 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250348 Reaction Name: Phosphorylation of SHC1 by ERBB4 homodimers See in Reactome R-HSA-1250353 ( R-HSA-1236394; R-HSA-1250342 ) R-HSA-1250353 Reaction Name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers See in Reactome R-HSA-1250357 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250357 Reaction Name: SHC1 binds P-ERBB4 isoform dimers See in Reactome R-HSA-1250370 ( R-HSA-1236394; R-HSA-1250342 ) R-HSA-1250370 Reaction Name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers See in Reactome R-HSA-1250380 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250380 Reaction Name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers See in Reactome R-HSA-1250383 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250383 Reaction Name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349 See in Reactome R-HSA-1250383 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250383 Reaction Name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 See in Reactome R-HSA-1250463 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1250463 Reaction Name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers See in Reactome R-HSA-1250486 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1250486 Reaction Name: Recruitment of GRB2:SOS1 to p-SHC1 in complex with phosphorylated ERBB2 heterodimers See in Reactome R-HSA-1251992 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1251992 Reaction Name: Cleavage of P-ERBB4jmA isoforms by ADAM17 See in Reactome R-HSA-1251997 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1251997 Reaction Name: Cleavage of ERBB4m80 by gamma-scretase complex See in Reactome R-HSA-1252013 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1252013 Reaction Name: Translocation of ERBB4s80 to the nucleus See in Reactome R-HSA-1253282 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1253282 Reaction Name: ERBB4 ubiquitination by WWP1/ITCH See in Reactome R-HSA-1253300 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1253300 Reaction Name: ERBB4 binds WWP1/ITCH ubiquitin ligases See in Reactome R-HSA-1253319 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253319 Reaction Name: ERBB4s80:TAB2:NCOR1 complex translocates to the nucleus See in Reactome R-HSA-1253321 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253321 Reaction Name: GFAP gene expression is inhibited by ERBB4:TAB2:NCOR1 See in Reactome R-HSA-1253325 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253325 Reaction Name: ERBB4s80 binds TAB2:NCOR1 complex See in Reactome R-HSA-1253343 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253343 Reaction Name: WWOX binds ERBB4s80 See in Reactome R-HSA-1254248 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254248 Reaction Name: Translocation of ERBB4s80:YAP1 complex to the nucleus See in Reactome R-HSA-1254251 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254251 Reaction Name: ERBB4s80 binds YAP1 See in Reactome R-HSA-1254285 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254285 Reaction Name: ERBB4s80:STAT5A complex translocates to the nucleus See in Reactome R-HSA-1254290 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254290 Reaction Name: CSN2 gene expression is stimulated by ERBB4s80:STAT5A See in Reactome R-HSA-1254291 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254291 Reaction Name: ERBB4s80 binds STAT5A See in Reactome R-HSA-1254376 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254376 Reaction Name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix See in Reactome R-HSA-1254386 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-1254386 Reaction Name: ERBB4s80 forms a complex with estrogen receptor ESR1 See in Reactome R-HSA-1254392 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-1254392 Reaction Name: PGR gene expression is stimulated by ERBB4s80:ESR1:estrogen See in Reactome R-HSA-1306969 ( R-HSA-1227986; R-HSA-1963640 ) R-HSA-1306969 Reaction Name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers See in Reactome R-HSA-1306972 ( R-HSA-1227986; R-HSA-1963640 ) R-HSA-1306972 Reaction Name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers See in Reactome R-HSA-1306979 ( R-HSA-1227986; R-HSA-1963642 ) R-HSA-1306979 Reaction Name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 See in Reactome R-HSA-1963563 ( R-HSA-1227986; R-HSA-8863795 ) R-HSA-1963563 Reaction Name: MATK (CSK homologous kinase) binds phosphorylated ERBB2 See in Reactome R-HSA-1963578 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1963578 Reaction Name: SHC1 binds phosphorylated ERBB2 heterodimers See in Reactome R-HSA-1963581 ( R-HSA-1227986 ) R-HSA-1963581 Reaction Name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers See in Reactome R-HSA-1963582 ( R-HSA-1227986 ) R-HSA-1963582 Reaction Name: Trans-autophosphorylation of ERBB2 heterodimers See in Reactome R-HSA-1963586 ( R-HSA-1227986 ) R-HSA-1963586 Reaction Name: SRC family kinases phosphorylate ERBB2 See in Reactome R-HSA-1963589 ( R-HSA-1227986 ) R-HSA-1963589 Reaction Name: ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR See in Reactome R-HSA-1963589 ( R-HSA-1227986 ) R-HSA-1963589 Reaction Name: ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 See in Reactome R-HSA-1973956 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1973956 Reaction Name: NEDD4 binds ERBB4jmAcyt1s80 dimer See in Reactome R-HSA-1977296 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1977296 Reaction Name: NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer See in Reactome R-HSA-1977958 ( R-HSA-1236394 ) R-HSA-1977958 Reaction Name: ERBB4 forms heterodimers with ERBB3 See in Reactome R-HSA-1977959 ( R-HSA-1236394 ) R-HSA-1977959 Reaction Name: ERBB4 forms heterodimers with EGFR See in Reactome R-HSA-2316434 ( R-HSA-1257604; R-HSA-6811558 ) R-HSA-2316434 Reaction Name: PI3K phosphorylates PIP2 to PIP3 See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-6785636 ( R-HSA-1227986; R-HSA-6785631 ) R-HSA-6785636 Reaction Name: Phosphorylated ERBB2 heterodimers bind MEMO1 See in Reactome R-HSA-6785648 ( R-HSA-1227986; R-HSA-6785631 ) R-HSA-6785648 Reaction Name: MEMO1 binds RHOA:GTP:DIAPH1 See in Reactome R-HSA-8847995 ( R-HSA-1227986; R-HSA-8847993 ) R-HSA-8847995 Reaction Name: Activated ERBB2 binds PTK6 (BRK) See in Reactome R-HSA-8848005 ( R-HSA-1227986; R-HSA-8847993 ) R-HSA-8848005 Reaction Name: ERBB2 promotes PTK6 autophosphorylation See in Reactome R-HSA-8863804 ( R-HSA-1227986; R-HSA-8863795 ) R-HSA-8863804 Reaction Name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 See in Reactome R-HSA-8954179 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954179 Reaction Name: S100B gene expression is inhibited by ERBB4:TAB2:NCOR1 See in Reactome R-HSA-8954182 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954182 Reaction Name: ERBB4s80:TAB2:NCOR1 complex binds S100B gene promoter See in Reactome R-HSA-8954185 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954185 Reaction Name: ERBB4s80:TAB2:NCOR1 complex binds GFAP gene promoter See in Reactome R-HSA-8954199 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-8954199 Reaction Name: CXCL12 gene expression is stimulated by ERBB4s80:ESR1:estrogen See in Reactome R-HSA-8954207 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-8954207 Reaction Name: ERBB4s80:ESR1 binds CXCL12 gene promoter See in Reactome R-HSA-8954208 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-8954208 Reaction Name: ERBB4s80:ESR1 binds PGR gene promoter See in Reactome R-HSA-8954224 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954224 Reaction Name: ERBB4s80:STAT5A binds CSN2 gene promoter See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9612219 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-9612219 Reaction Name: ERBB4s80 binds to SRC See in Reactome R-HSA-9612243 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612243 Reaction Name: APOE gene transcription is stimulated by ERBB4s80 See in Reactome R-HSA-9612246 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612246 Reaction Name: ERBB4s80 binds the APOE gene See in Reactome R-HSA-9612255 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612255 Reaction Name: ERBB4s80 binds ADAP1 gene See in Reactome R-HSA-9612257 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612257 Reaction Name: ADAP1 gene expression is inhibited by ERBB4s80 See in Reactome R-HSA-9612277 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612277 Reaction Name: SPARC gene transcription is stimulated by ERBB4s80 See in Reactome R-HSA-9612278 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612278 Reaction Name: ERBB4s80 binds SPARC gene See in Reactome R-HSA-9612440 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612440 Reaction Name: ERBB4s80 binds the MXD4 gene See in Reactome R-HSA-9612444 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612444 Reaction Name: ERBB4s80 binds STMN1 gene See in Reactome R-HSA-9612445 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612445 Reaction Name: STMN1 gene expression is stimulated by ERBB4s80 See in Reactome R-HSA-9612448 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612448 Reaction Name: MXD4 gene expression is stimulated by ERBB4s80 See in Reactome R-HSA-9612593 ( R-HSA-1236394 ) R-HSA-9612593 Reaction Name: ERBB4 binds DLG4 See in Reactome R-HSA-9612639 ( R-HSA-1236394 ) R-HSA-9612639 Reaction Name: NRG2-activated ERBB4 binds GABA receptors through GABRA1 See in Reactome R-HSA-9612671 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612671 Reaction Name: ERBB4 gene expression is stimulated by ERBB4s80:ESR1 See in Reactome R-HSA-9612672 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612672 Reaction Name: ERBB4s80:ESR1 binds ERBB4 gene promoter See in Reactome
MONDO:0014837	SRC	P12931	2.7.10.2	R-HSA-418886 R-HSA-418886 Reactome Name: Netrin mediated repulsion signals See in Reactome R-HSA-171007 R-HSA-171007 Reactome Name: p38MAPK events See in Reactome R-HSA-428542 R-HSA-428542 Reactome Name: Regulation of commissural axon pathfinding by SLIT and ROBO See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-8940973 R-HSA-8940973 Reactome Name: RUNX2 regulates osteoblast differentiation See in Reactome R-HSA-418885 R-HSA-418885 Reactome Name: DCC mediated attractive signaling See in Reactome R-HSA-437239 R-HSA-437239 Reactome Name: Recycling pathway of L1 See in Reactome R-HSA-418592 R-HSA-418592 Reactome Name: ADP signalling through P2Y purinoceptor 1 See in Reactome R-HSA-430116 R-HSA-430116 Reactome Name: GP1b-IX-V activation signalling See in Reactome R-HSA-5663220 R-HSA-5663220 Reactome Name: RHO GTPases Activate Formins See in Reactome R-HSA-186763 R-HSA-186763 Reactome Name: Downstream signal transduction See in Reactome R-HSA-180292 R-HSA-180292 Reactome Name: GAB1 signalosome See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-3928662 R-HSA-3928662 Reactome Name: EPHB-mediated forward signaling See in Reactome R-HSA-418555 R-HSA-418555 Reactome Name: G alpha (s) signalling events See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-9032500 R-HSA-9032500 Reactome Name: Activated NTRK2 signals through FYN See in Reactome R-HSA-1257604 R-HSA-1257604 Reactome Name: PIP3 activates AKT signaling See in Reactome R-HSA-389513 R-HSA-389513 Reactome Name: CTLA4 inhibitory signaling See in Reactome R-HSA-8934903 R-HSA-8934903 Reactome Name: Receptor Mediated Mitophagy See in Reactome R-HSA-8853659 R-HSA-8853659 Reactome Name: RET signaling See in Reactome R-HSA-372708 R-HSA-372708 Reactome Name: p130Cas linkage to MAPK signaling for integrins See in Reactome R-HSA-389356 R-HSA-389356 Reactome Name: CD28 co-stimulation See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-391160 R-HSA-391160 Reactome Name: Signal regulatory protein family interactions See in Reactome R-HSA-4420097 R-HSA-4420097 Reactome Name: VEGFA-VEGFR2 Pathway See in Reactome R-HSA-1433559 R-HSA-1433559 Reactome Name: Regulation of KIT signaling See in Reactome R-HSA-2029481 R-HSA-2029481 Reactome Name: FCGR activation See in Reactome R-HSA-1295596 R-HSA-1295596 Reactome Name: Spry regulation of FGF signaling See in Reactome R-HSA-8934593 R-HSA-8934593 Reactome Name: Regulation of RUNX1 Expression and Activity See in Reactome R-HSA-1433557 R-HSA-1433557 Reactome Name: Signaling by SCF-KIT See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-375165 R-HSA-375165 Reactome Name: NCAM signaling for neurite out-growth See in Reactome R-HSA-5607764 R-HSA-5607764 Reactome Name: CLEC7A (Dectin-1) signaling See in Reactome R-HSA-5674135 R-HSA-5674135 Reactome Name: MAP2K and MAPK activation See in Reactome R-HSA-8874081 R-HSA-8874081 Reactome Name: MET activates PTK2 signaling See in Reactome R-HSA-1253288 R-HSA-1253288 Reactome Name: Downregulation of ERBB4 signaling See in Reactome R-HSA-2682334 R-HSA-2682334 Reactome Name: EPH-Ephrin signaling See in Reactome R-HSA-9009391 R-HSA-9009391 Reactome Name: Extra-nuclear estrogen signaling See in Reactome R-HSA-177929 R-HSA-177929 Reactome Name: Signaling by EGFR See in Reactome R-HSA-1251985 R-HSA-1251985 Reactome Name: Nuclear signaling by ERBB4 See in Reactome R-HSA-9603381 R-HSA-9603381 Reactome Name: Activated NTRK3 signals through PI3K See in Reactome R-HSA-354194 R-HSA-354194 Reactome Name: GRB2:SOS provides linkage to MAPK signaling for Integrins See in Reactome R-HSA-3928664 R-HSA-3928664 Reactome Name: Ephrin signaling See in Reactome R-HSA-456926 R-HSA-456926 Reactome Name: Thrombin signalling through proteinase activated receptors (PARs) See in Reactome R-HSA-354192 R-HSA-354192 Reactome Name: Integrin signaling See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-3928665 R-HSA-3928665 Reactome Name: EPH-ephrin mediated repulsion of cells See in Reactome R-HSA-191650 R-HSA-191650 Reactome Name: Regulation of gap junction activity See in Reactome R-HSA-9013420 R-HSA-9013420 Reactome Name: RHOU GTPase cycle See in Reactome R-HSA-6811558 R-HSA-6811558 Reactome Name: PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling See in Reactome R-HSA-210990 R-HSA-210990 Reactome Name: PECAM1 interactions See in Reactome R-HSA-1227986 R-HSA-1227986 Reactome Name: Signaling by ERBB2 See in Reactome R-HSA-5218921 R-HSA-5218921 Reactome Name: VEGFR2 mediated cell proliferation See in Reactome R-HSA-3928663 R-HSA-3928663 Reactome Name: EPHA-mediated growth cone collapse See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-376176 R-HSA-376176 Reactome Name: Signaling by ROBO receptors See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-8941326 R-HSA-8941326 Reactome Name: RUNX2 regulates bone development See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-202733 R-HSA-202733 Reactome Name: Cell surface interactions at the vascular wall See in Reactome R-HSA-1500931 R-HSA-1500931 Reactome Name: Cell-Cell communication See in Reactome R-HSA-195258 R-HSA-195258 Reactome Name: RHO GTPase Effectors See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-373760 R-HSA-373760 Reactome Name: L1CAM interactions See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome R-HSA-76009 R-HSA-76009 Reactome Name: Platelet Aggregation (Plug Formation) See in Reactome R-HSA-9612973 R-HSA-9612973 Reactome Name: Autophagy See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome R-HSA-388841 R-HSA-388841 Reactome Name: Costimulation by the CD28 family See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-5654726 R-HSA-5654726 Reactome Name: Negative regulation of FGFR1 signaling See in Reactome R-HSA-5654727 R-HSA-5654727 Reactome Name: Negative regulation of FGFR2 signaling See in Reactome R-HSA-199418 R-HSA-199418 Reactome Name: Negative regulation of the PI3K/AKT network See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-5205647 R-HSA-5205647 Reactome Name: Mitophagy See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-8875878 R-HSA-8875878 Reactome Name: MET promotes cell motility See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5654743 R-HSA-5654743 Reactome Name: Signaling by FGFR4 See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-190236 R-HSA-190236 Reactome Name: Signaling by FGFR See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-9663891 R-HSA-9663891 Reactome Name: Selective autophagy See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-392518 R-HSA-392518 Reactome Name: Signal amplification See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-157858 R-HSA-157858 Reactome Name: Gap junction trafficking and regulation See in Reactome R-HSA-9006115 R-HSA-9006115 Reactome Name: Signaling by NTRK2 (TRKB) See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-1236394 R-HSA-1236394 Reactome Name: Signaling by ERBB4 See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome R-HSA-1632852 R-HSA-1632852 Reactome Name: Macroautophagy See in Reactome R-HSA-6806834 R-HSA-6806834 Reactome Name: Signaling by MET See in Reactome R-HSA-187687 R-HSA-187687 Reactome Name: Signalling to ERKs See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-5654738 R-HSA-5654738 Reactome Name: Signaling by FGFR2 See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5654736 R-HSA-5654736 Reactome Name: Signaling by FGFR1 See in Reactome R-HSA-5654733 R-HSA-5654733 Reactome Name: Negative regulation of FGFR4 signaling See in Reactome R-HSA-5654732 R-HSA-5654732 Reactome Name: Negative regulation of FGFR3 signaling See in Reactome R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-9034015 R-HSA-9034015 Reactome Name: Signaling by NTRK3 (TRKC) See in Reactome R-HSA-186797 R-HSA-186797 Reactome Name: Signaling by PDGF See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-5654741 R-HSA-5654741 Reactome Name: Signaling by FGFR3 See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-167044 R-HSA-167044 Reactome Name: Signalling to RAS See in Reactome R-HSA-373752 R-HSA-373752 Reactome Name: Netrin-1 signaling See in Reactome	Immune System Cell-Cell communication Cell Cycle Developmental Biology Autophagy Gene expression (Transcription) Neuronal System Signal Transduction Vesicle-mediated transport Hemostasis	R-HSA-1252013 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1252013 Reaction Name: Translocation of ERBB4s80 to the nucleus See in Reactome R-HSA-177923 ( R-HSA-177929; R-HSA-180292 ) R-HSA-177923 Reaction Name: Sustained activation of SRC kinase by SHP2 See in Reactome R-HSA-186819 ( R-HSA-186763 ) R-HSA-186819 Reaction Name: SH2 domain of Src binds to the active receptor See in Reactome R-HSA-1963586 ( R-HSA-1227986 ) R-HSA-1963586 Reaction Name: SRC family kinases phosphorylate ERBB2 See in Reactome R-HSA-2316434 ( R-HSA-1257604; R-HSA-6811558 ) R-HSA-2316434 Reaction Name: PI3K phosphorylates PIP2 to PIP3 See in Reactome R-HSA-354066 ( R-HSA-354192 ) R-HSA-354066 Reaction Name: Translocation of PTK2 to Focal complexes See in Reactome R-HSA-354073 ( R-HSA-354192 ) R-HSA-354073 Reaction Name: Autophosphorylation of PTK2 at Y397 See in Reactome R-HSA-354077 ( R-HSA-354192 ) R-HSA-354077 Reaction Name: Integrin alphaIIb beta3 activation See in Reactome R-HSA-354087 ( R-HSA-354192; R-HSA-354194 ) R-HSA-354087 Reaction Name: Recruitment of GRB2 to p-PTK2 See in Reactome R-HSA-354124 ( R-HSA-354192 ) R-HSA-354124 Reaction Name: Phosphorylation of pPTK2 by SRC See in Reactome R-HSA-354149 ( R-HSA-354192 ) R-HSA-354149 Reaction Name: Interaction of integrin alphaIIb beta3 with Fibrinogen See in Reactome R-HSA-354165 ( R-HSA-354192; R-HSA-354194 ) R-HSA-354165 Reaction Name: Interaction of SOS with GRB2 bound to FADK1 See in Reactome R-HSA-372693 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372693 Reaction Name: Phosphorylation of BCAR1 by SRC-PTK2 complex See in Reactome R-HSA-372697 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372697 Reaction Name: Crk binding to p130cas See in Reactome R-HSA-372705 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372705 Reaction Name: Recruitment of BCAR1 to PTK2 complex See in Reactome R-HSA-373716 ( R-HSA-418885 ) R-HSA-373716 Reaction Name: DCC interacting NCK-1 See in Reactome R-HSA-374701 ( R-HSA-418885 ) R-HSA-374701 Reaction Name: Phosphorylation of DCC by Fyn See in Reactome R-HSA-377640 ( R-HSA-354192 ) R-HSA-377640 Reaction Name: Autophosphorylation of SRC See in Reactome R-HSA-377641 ( R-HSA-354192 ) R-HSA-377641 Reaction Name: Clustering of Integrin alphaIIb beta3 complexes See in Reactome R-HSA-377643 ( R-HSA-354192 ) R-HSA-377643 Reaction Name: Dephosphorylation of inactive SRC by PTPB1 See in Reactome R-HSA-377644 ( R-HSA-354192 ) R-HSA-377644 Reaction Name: Release of CSK from SRC See in Reactome R-HSA-380780 ( R-HSA-186763 ) R-HSA-380780 Reaction Name: Activation of Src See in Reactome R-HSA-418850 ( R-HSA-418885 ) R-HSA-418850 Reaction Name: Activation of Cdc42 See in Reactome R-HSA-418856 ( R-HSA-418885 ) R-HSA-418856 Reaction Name: Activation of Rac1 See in Reactome R-HSA-418858 ( R-HSA-418885 ) R-HSA-418858 Reaction Name: RhoGTPase GEF's recruited to DCC See in Reactome R-HSA-418859 ( R-HSA-418886 ) R-HSA-418859 Reaction Name: Phosphorylation of Unc5C See in Reactome R-HSA-418865 ( R-HSA-418885 ) R-HSA-418865 Reaction Name: Recruitment of ABLIM to the plasma membrane See in Reactome R-HSA-418868 ( R-HSA-418885 ) R-HSA-418868 Reaction Name: Recruitment of Src and Fyn to DCC:FADK1 See in Reactome R-HSA-418874 ( R-HSA-418885 ) R-HSA-418874 Reaction Name: Recruitment and activation of N-WASP by Cdc42 See in Reactome R-HSA-429415 ( R-HSA-354192 ) R-HSA-429415 Reaction Name: SYK binds to integrin alphaIIb beta3 See in Reactome R-HSA-429441 ( R-HSA-354192 ) R-HSA-429441 Reaction Name: SYK activation by SRC See in Reactome R-HSA-432096 ( R-HSA-354192 ) R-HSA-432096 Reaction Name: Activated integrin alphaIIb beta3 binds SHC1 See in Reactome R-HSA-443905 ( R-HSA-354192 ) R-HSA-443905 Reaction Name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow See in Reactome R-HSA-443910 ( R-HSA-354192 ) R-HSA-443910 Reaction Name: SHC1 dissociates from integrin alphaIIb beta3 See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-5672972 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672972 Reaction Name: MAP2Ks and MAPKs bind to the activated RAF complex See in Reactome R-HSA-5672973 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672973 Reaction Name: MAP2Ks phosphorylate MAPKs See in Reactome R-HSA-5672978 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672978 Reaction Name: RAF phosphorylates MAP2K dimer See in Reactome R-HSA-5672980 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672980 Reaction Name: Dissociation of RAS:RAF complex See in Reactome R-HSA-8874080 ( R-HSA-8874081 ) R-HSA-8874080 Reaction Name: SRC phosphorylates PTK2 See in Reactome R-HSA-8874082 ( R-HSA-8874081 ) R-HSA-8874082 Reaction Name: MET phosphorylates PTK2 See in Reactome R-HSA-8874083 ( R-HSA-8874081 ) R-HSA-8874083 Reaction Name: p-Y397-PTK2 binds SRC See in Reactome R-HSA-8937682 ( R-HSA-8934593 ) R-HSA-8937682 Reaction Name: RUNX1 binds SRC See in Reactome R-HSA-8937728 ( R-HSA-8934593 ) R-HSA-8937728 Reaction Name: SRC phosphorylates RUNX1 See in Reactome R-HSA-8937792 ( R-HSA-8941858 ) R-HSA-8937792 Reaction Name: RUNX3 binds SRC See in Reactome R-HSA-8937807 ( R-HSA-8941858 ) R-HSA-8937807 Reaction Name: SRC phosphorylates RUNX3 See in Reactome R-HSA-8937814 ( R-HSA-8941858 ) R-HSA-8937814 Reaction Name: RUNX3 translocates to the nucleus See in Reactome R-HSA-8937820 ( R-HSA-8940973 ) R-HSA-8937820 Reaction Name: SRC,YES1 bind YAP1 See in Reactome R-HSA-8937844 ( R-HSA-8940973 ) R-HSA-8937844 Reaction Name: SRC,YES1 phosphorylate YAP1 See in Reactome R-HSA-8964242 ( R-HSA-418594 ) R-HSA-8964242 Reaction Name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC See in Reactome R-HSA-8964252 ( R-HSA-418555 ) R-HSA-8964252 Reaction Name: G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC See in Reactome R-HSA-8964278 ( R-HSA-418555 ) R-HSA-8964278 Reaction Name: G protein alpha (s):GTP binds SRC See in Reactome R-HSA-8964287 ( R-HSA-418555 ) R-HSA-8964287 Reaction Name: G alpha (s):GTP:SRC dissociates See in Reactome R-HSA-8964311 ( R-HSA-418594 ) R-HSA-8964311 Reaction Name: G alpha (i):GTP binds SRC See in Reactome R-HSA-8964329 ( R-HSA-418594 ) R-HSA-8964329 Reaction Name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC See in Reactome R-HSA-9011241 ( R-HSA-428542 ) R-HSA-9011241 Reaction Name: SRC phosphorylates ROBO3.1 in response to NTN1 See in Reactome R-HSA-9021596 ( R-HSA-9009391 ) R-HSA-9021596 Reaction Name: Membrane estrogen receptors bind SRC See in Reactome R-HSA-9021609 ( R-HSA-9009391 ) R-HSA-9021609 Reaction Name: ESR-associated SRC autophosphorylates See in Reactome R-HSA-9021660 ( R-HSA-9009391 ) R-HSA-9021660 Reaction Name: PI3K binds membrane-associated estrogen receptors See in Reactome R-HSA-9037040 ( R-HSA-9032500 ) R-HSA-9037040 Reaction Name: SRC,FYN phosphorylate NTRK2 See in Reactome R-HSA-9603419 ( R-HSA-9603381 ) R-HSA-9603419 Reaction Name: Activated NTRK3 binds SRC See in Reactome R-HSA-9603420 ( R-HSA-9603381 ) R-HSA-9603420 Reaction Name: Activated NTRK3 promotes SRC autophosphorylation See in Reactome R-HSA-9603437 ( R-HSA-9603381 ) R-HSA-9603437 Reaction Name: Activated NTRK3 binds IRS1 See in Reactome R-HSA-9603445 ( R-HSA-9603381 ) R-HSA-9603445 Reaction Name: Activated NTRK3 stimulates PI3K activity See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9612219 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-9612219 Reaction Name: ERBB4s80 binds to SRC See in Reactome R-HSA-9624014 ( R-HSA-418555 ) R-HSA-9624014 Reaction Name: SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 See in Reactome R-HSA-9632412 ( R-HSA-9009391 ) R-HSA-9632412 Reaction Name: PTK2 is recruited to methylated ESR1 See in Reactome R-HSA-9657599 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657599 Reaction Name: Dual mechanism MAP2K inhibitors bind MAP2Ks See in Reactome R-HSA-9657603 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657603 Reaction Name: Dual mechanism MAPK inhibitors bind MAPKs See in Reactome R-HSA-9657606 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657606 Reaction Name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks See in Reactome R-HSA-9657608 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657608 Reaction Name: Single mechanism MAPK inhibitors bind phosphorylated MAPK See in Reactome R-HSA-9726848 ( R-HSA-9013420 ) R-HSA-9726848 Reaction Name: SRC phosphorylates RHOU See in Reactome
MONDO:0016996	ERBB4	Q15303	2.7.10.1	R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-1963640 R-HSA-1963640 Reactome Name: GRB2 events in ERBB2 signaling See in Reactome R-HSA-1257604 R-HSA-1257604 Reactome Name: PIP3 activates AKT signaling See in Reactome R-HSA-1250347 R-HSA-1250347 Reactome Name: SHC1 events in ERBB4 signaling See in Reactome R-HSA-1250342 R-HSA-1250342 Reactome Name: PI3K events in ERBB4 signaling See in Reactome R-HSA-1963642 R-HSA-1963642 Reactome Name: PI3K events in ERBB2 signaling See in Reactome R-HSA-6785631 R-HSA-6785631 Reactome Name: ERBB2 Regulates Cell Motility See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-6811558 R-HSA-6811558 Reactome Name: PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling See in Reactome R-HSA-1250196 R-HSA-1250196 Reactome Name: SHC1 events in ERBB2 signaling See in Reactome R-HSA-1227986 R-HSA-1227986 Reactome Name: Signaling by ERBB2 See in Reactome R-HSA-1236394 R-HSA-1236394 Reactome Name: Signaling by ERBB4 See in Reactome R-HSA-1253288 R-HSA-1253288 Reactome Name: Downregulation of ERBB4 signaling See in Reactome R-HSA-8847993 R-HSA-8847993 Reactome Name: ERBB2 Activates PTK6 Signaling See in Reactome R-HSA-8863795 R-HSA-8863795 Reactome Name: Downregulation of ERBB2 signaling See in Reactome R-HSA-1251985 R-HSA-1251985 Reactome Name: Nuclear signaling by ERBB4 See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-199418 R-HSA-199418 Reactome Name: Negative regulation of the PI3K/AKT network See in Reactome R-HSA-8848021 R-HSA-8848021 Reactome Name: Signaling by PTK6 See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-9006927 R-HSA-9006927 Reactome Name: Signaling by Non-Receptor Tyrosine Kinases See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Neuronal System Signal Transduction	R-HSA-1236398 ( R-HSA-1236394 ) R-HSA-1236398 Reaction Name: ERBB4 binds NRGs or EGF-like ligands See in Reactome R-HSA-1250195 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1250195 Reaction Name: SHC1 phosphorylation by ERBB2 heterodimers See in Reactome R-HSA-1250220 ( R-HSA-1236394 ) R-HSA-1250220 Reaction Name: Homodimerization of ERBB4 See in Reactome R-HSA-1250315 ( R-HSA-1236394 ) R-HSA-1250315 Reaction Name: Trans-autophosphorylation of ERBB4 homodimers See in Reactome R-HSA-1250346 ( R-HSA-1227986; R-HSA-1963642 ) R-HSA-1250346 Reaction Name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers See in Reactome R-HSA-1250348 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250348 Reaction Name: Phosphorylation of SHC1 by ERBB4 homodimers See in Reactome R-HSA-1250353 ( R-HSA-1236394; R-HSA-1250342 ) R-HSA-1250353 Reaction Name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers See in Reactome R-HSA-1250357 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250357 Reaction Name: SHC1 binds P-ERBB4 isoform dimers See in Reactome R-HSA-1250370 ( R-HSA-1236394; R-HSA-1250342 ) R-HSA-1250370 Reaction Name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers See in Reactome R-HSA-1250380 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250380 Reaction Name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers See in Reactome R-HSA-1250383 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250383 Reaction Name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349 See in Reactome R-HSA-1250383 ( R-HSA-1236394; R-HSA-1250347 ) R-HSA-1250383 Reaction Name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 See in Reactome R-HSA-1250463 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1250463 Reaction Name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-SHC1:Phosphorylated ERBB2 heterodimers See in Reactome R-HSA-1250486 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1250486 Reaction Name: Recruitment of GRB2:SOS1 to p-SHC1 in complex with phosphorylated ERBB2 heterodimers See in Reactome R-HSA-1251992 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1251992 Reaction Name: Cleavage of P-ERBB4jmA isoforms by ADAM17 See in Reactome R-HSA-1251997 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1251997 Reaction Name: Cleavage of ERBB4m80 by gamma-scretase complex See in Reactome R-HSA-1252013 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1252013 Reaction Name: Translocation of ERBB4s80 to the nucleus See in Reactome R-HSA-1253282 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1253282 Reaction Name: ERBB4 ubiquitination by WWP1/ITCH See in Reactome R-HSA-1253300 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1253300 Reaction Name: ERBB4 binds WWP1/ITCH ubiquitin ligases See in Reactome R-HSA-1253319 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253319 Reaction Name: ERBB4s80:TAB2:NCOR1 complex translocates to the nucleus See in Reactome R-HSA-1253321 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253321 Reaction Name: GFAP gene expression is inhibited by ERBB4:TAB2:NCOR1 See in Reactome R-HSA-1253325 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253325 Reaction Name: ERBB4s80 binds TAB2:NCOR1 complex See in Reactome R-HSA-1253343 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1253343 Reaction Name: WWOX binds ERBB4s80 See in Reactome R-HSA-1254248 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254248 Reaction Name: Translocation of ERBB4s80:YAP1 complex to the nucleus See in Reactome R-HSA-1254251 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254251 Reaction Name: ERBB4s80 binds YAP1 See in Reactome R-HSA-1254285 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254285 Reaction Name: ERBB4s80:STAT5A complex translocates to the nucleus See in Reactome R-HSA-1254290 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254290 Reaction Name: CSN2 gene expression is stimulated by ERBB4s80:STAT5A See in Reactome R-HSA-1254291 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254291 Reaction Name: ERBB4s80 binds STAT5A See in Reactome R-HSA-1254376 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1254376 Reaction Name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix See in Reactome R-HSA-1254386 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-1254386 Reaction Name: ERBB4s80 forms a complex with estrogen receptor ESR1 See in Reactome R-HSA-1254392 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-1254392 Reaction Name: PGR gene expression is stimulated by ERBB4s80:ESR1:estrogen See in Reactome R-HSA-1306969 ( R-HSA-1227986; R-HSA-1963640 ) R-HSA-1306969 Reaction Name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers See in Reactome R-HSA-1306972 ( R-HSA-1227986; R-HSA-1963640 ) R-HSA-1306972 Reaction Name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers See in Reactome R-HSA-1306979 ( R-HSA-1227986; R-HSA-1963642 ) R-HSA-1306979 Reaction Name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 See in Reactome R-HSA-1963563 ( R-HSA-1227986; R-HSA-8863795 ) R-HSA-1963563 Reaction Name: MATK (CSK homologous kinase) binds phosphorylated ERBB2 See in Reactome R-HSA-1963578 ( R-HSA-1227986; R-HSA-1250196 ) R-HSA-1963578 Reaction Name: SHC1 binds phosphorylated ERBB2 heterodimers See in Reactome R-HSA-1963581 ( R-HSA-1227986 ) R-HSA-1963581 Reaction Name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers See in Reactome R-HSA-1963582 ( R-HSA-1227986 ) R-HSA-1963582 Reaction Name: Trans-autophosphorylation of ERBB2 heterodimers See in Reactome R-HSA-1963586 ( R-HSA-1227986 ) R-HSA-1963586 Reaction Name: SRC family kinases phosphorylate ERBB2 See in Reactome R-HSA-1963589 ( R-HSA-1227986 ) R-HSA-1963589 Reaction Name: ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR See in Reactome R-HSA-1963589 ( R-HSA-1227986 ) R-HSA-1963589 Reaction Name: ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 See in Reactome R-HSA-1973956 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1973956 Reaction Name: NEDD4 binds ERBB4jmAcyt1s80 dimer See in Reactome R-HSA-1977296 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-1977296 Reaction Name: NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer See in Reactome R-HSA-1977958 ( R-HSA-1236394 ) R-HSA-1977958 Reaction Name: ERBB4 forms heterodimers with ERBB3 See in Reactome R-HSA-1977959 ( R-HSA-1236394 ) R-HSA-1977959 Reaction Name: ERBB4 forms heterodimers with EGFR See in Reactome R-HSA-2316434 ( R-HSA-1257604; R-HSA-6811558 ) R-HSA-2316434 Reaction Name: PI3K phosphorylates PIP2 to PIP3 See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-6785636 ( R-HSA-1227986; R-HSA-6785631 ) R-HSA-6785636 Reaction Name: Phosphorylated ERBB2 heterodimers bind MEMO1 See in Reactome R-HSA-6785648 ( R-HSA-1227986; R-HSA-6785631 ) R-HSA-6785648 Reaction Name: MEMO1 binds RHOA:GTP:DIAPH1 See in Reactome R-HSA-8847995 ( R-HSA-1227986; R-HSA-8847993 ) R-HSA-8847995 Reaction Name: Activated ERBB2 binds PTK6 (BRK) See in Reactome R-HSA-8848005 ( R-HSA-1227986; R-HSA-8847993 ) R-HSA-8848005 Reaction Name: ERBB2 promotes PTK6 autophosphorylation See in Reactome R-HSA-8863804 ( R-HSA-1227986; R-HSA-8863795 ) R-HSA-8863804 Reaction Name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 See in Reactome R-HSA-8954179 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954179 Reaction Name: S100B gene expression is inhibited by ERBB4:TAB2:NCOR1 See in Reactome R-HSA-8954182 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954182 Reaction Name: ERBB4s80:TAB2:NCOR1 complex binds S100B gene promoter See in Reactome R-HSA-8954185 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954185 Reaction Name: ERBB4s80:TAB2:NCOR1 complex binds GFAP gene promoter See in Reactome R-HSA-8954199 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-8954199 Reaction Name: CXCL12 gene expression is stimulated by ERBB4s80:ESR1:estrogen See in Reactome R-HSA-8954207 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-8954207 Reaction Name: ERBB4s80:ESR1 binds CXCL12 gene promoter See in Reactome R-HSA-8954208 ( R-HSA-1236394; R-HSA-1251985; R-HSA-9018519 ) R-HSA-8954208 Reaction Name: ERBB4s80:ESR1 binds PGR gene promoter See in Reactome R-HSA-8954224 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-8954224 Reaction Name: ERBB4s80:STAT5A binds CSN2 gene promoter See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9612219 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-9612219 Reaction Name: ERBB4s80 binds to SRC See in Reactome R-HSA-9612243 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612243 Reaction Name: APOE gene transcription is stimulated by ERBB4s80 See in Reactome R-HSA-9612246 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612246 Reaction Name: ERBB4s80 binds the APOE gene See in Reactome R-HSA-9612255 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612255 Reaction Name: ERBB4s80 binds ADAP1 gene See in Reactome R-HSA-9612257 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612257 Reaction Name: ADAP1 gene expression is inhibited by ERBB4s80 See in Reactome R-HSA-9612277 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612277 Reaction Name: SPARC gene transcription is stimulated by ERBB4s80 See in Reactome R-HSA-9612278 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612278 Reaction Name: ERBB4s80 binds SPARC gene See in Reactome R-HSA-9612440 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612440 Reaction Name: ERBB4s80 binds the MXD4 gene See in Reactome R-HSA-9612444 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612444 Reaction Name: ERBB4s80 binds STMN1 gene See in Reactome R-HSA-9612445 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612445 Reaction Name: STMN1 gene expression is stimulated by ERBB4s80 See in Reactome R-HSA-9612448 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612448 Reaction Name: MXD4 gene expression is stimulated by ERBB4s80 See in Reactome R-HSA-9612593 ( R-HSA-1236394 ) R-HSA-9612593 Reaction Name: ERBB4 binds DLG4 See in Reactome R-HSA-9612639 ( R-HSA-1236394 ) R-HSA-9612639 Reaction Name: NRG2-activated ERBB4 binds GABA receptors through GABRA1 See in Reactome R-HSA-9612671 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612671 Reaction Name: ERBB4 gene expression is stimulated by ERBB4s80:ESR1 See in Reactome R-HSA-9612672 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-9612672 Reaction Name: ERBB4s80:ESR1 binds ERBB4 gene promoter See in Reactome
MONDO:0030919	CAMK2A	Q9UQM7	2.7.11.17	R-HSA-111932 R-HSA-111932 Reactome Name: CaMK IV-mediated phosphorylation of CREB See in Reactome R-HSA-9617324 R-HSA-9617324 Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission See in Reactome R-HSA-5576892 R-HSA-5576892 Reactome Name: Phase 0 - rapid depolarisation See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-399719 R-HSA-399719 Reactome Name: Trafficking of AMPA receptors See in Reactome R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-877300 R-HSA-877300 Reactome Name: Interferon gamma signaling See in Reactome R-HSA-438066 R-HSA-438066 Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation See in Reactome R-HSA-442982 R-HSA-442982 Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-936837 R-HSA-936837 Reactome Name: Ion transport by P-type ATPases See in Reactome R-HSA-9609736 R-HSA-9609736 Reactome Name: Assembly and cell surface presentation of NMDA receptors See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-442742 R-HSA-442742 Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-913531 R-HSA-913531 Reactome Name: Interferon Signaling See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-399721 R-HSA-399721 Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Muscle contraction Immune System Transport of small molecules Gene expression (Transcription) Neuronal System Cellular responses to stimuli Signal Transduction	R-HSA-416320 ( R-HSA-399719 ) R-HSA-416320 Reaction Name: Trafficking of GluR1-containing AMPA receptors See in Reactome R-HSA-427910 ( R-HSA-5578775; R-HSA-936837 ) R-HSA-427910 Reaction Name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen See in Reactome R-HSA-432162 ( R-HSA-438066 ) R-HSA-432162 Reaction Name: Unblocking of GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-432164 ( R-HSA-438066 ) R-HSA-432164 Reaction Name: Ca2+ influx into the post-synaptic cell See in Reactome R-HSA-432172 ( R-HSA-438066 ) R-HSA-432172 Reaction Name: Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor See in Reactome R-HSA-4332356 ( R-HSA-4086398 ) R-HSA-4332356 Reaction Name: CAMK2 binds MAP3K7 See in Reactome R-HSA-4332358 ( R-HSA-4086398 ) R-HSA-4332358 Reaction Name: Dissociation of CaM and CAMK2 autophosphorylation See in Reactome R-HSA-4332359 ( R-HSA-4086398 ) R-HSA-4332359 Reaction Name: Active calmodulin binds CAMK2 See in Reactome R-HSA-4332363 ( R-HSA-4086398 ) R-HSA-4332363 Reaction Name: Autophosphorylation and activation of CAMK2 See in Reactome R-HSA-4332388 ( R-HSA-4086398 ) R-HSA-4332388 Reaction Name: Activation of MAP3K7 in response to WNT See in Reactome R-HSA-438037 ( R-HSA-438066 ) R-HSA-438037 Reaction Name: Membrane depolarization upon activation of Ca impermeable AMPA receptors See in Reactome R-HSA-442725 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-442725 Reaction Name: CaMKII binds activated calmodulin See in Reactome R-HSA-442732 ( R-HSA-442982 ) R-HSA-442732 Reaction Name: NMDA-activated RASGRF1 activates RAS See in Reactome R-HSA-442760 ( R-HSA-442982 ) R-HSA-442760 Reaction Name: Activation of RasGRF See in Reactome R-HSA-445367 ( R-HSA-9620244 ) R-HSA-445367 Reaction Name: CaMKII binds activated NMDA receptor See in Reactome R-HSA-5082387 ( R-HSA-3371571 ) R-HSA-5082387 Reaction Name: Phosphorylation of HSF1 at Ser230 induces transactivation See in Reactome R-HSA-5576895 ( R-HSA-5576892 ) R-HSA-5576895 Reaction Name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-9006992 ( R-HSA-9022692 ) R-HSA-9006992 Reaction Name: MECP2 is phosphorylated at S423 See in Reactome R-HSA-909552 ( R-HSA-877300 ) R-HSA-909552 Reaction Name: Phosphorylation of STAT1 at Ser727 See in Reactome R-HSA-9611368 ( R-HSA-9609736 ) R-HSA-9611368 Reaction Name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9614185 ( R-HSA-438066 ) R-HSA-9614185 Reaction Name: Mg2+ binds GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-9617326 ( R-HSA-9617324 ) R-HSA-9617326 Reaction Name: CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 See in Reactome R-HSA-9617583 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-9617583 Reaction Name: CaMKII autophosphorylates See in Reactome R-HSA-9618750 ( R-HSA-9620244 ) R-HSA-9618750 Reaction Name: CaMKII phosphorylates AMPA receptor See in Reactome R-HSA-9619449 ( R-HSA-9617324 ) R-HSA-9619449 Reaction Name: PPM1F dephosphorylates p-T286-CaMKII See in Reactome
MONDO:0030920	CAMK2B	Q13554	2.7.11.17	R-HSA-442729 R-HSA-442729 Reactome Name: CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde See in Reactome R-HSA-111932 R-HSA-111932 Reactome Name: CaMK IV-mediated phosphorylation of CREB See in Reactome R-HSA-9617324 R-HSA-9617324 Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission See in Reactome R-HSA-5576892 R-HSA-5576892 Reactome Name: Phase 0 - rapid depolarisation See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-399719 R-HSA-399719 Reactome Name: Trafficking of AMPA receptors See in Reactome R-HSA-877300 R-HSA-877300 Reactome Name: Interferon gamma signaling See in Reactome R-HSA-438066 R-HSA-438066 Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation See in Reactome R-HSA-442982 R-HSA-442982 Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-936837 R-HSA-936837 Reactome Name: Ion transport by P-type ATPases See in Reactome R-HSA-9609736 R-HSA-9609736 Reactome Name: Assembly and cell surface presentation of NMDA receptors See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-442742 R-HSA-442742 Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-913531 R-HSA-913531 Reactome Name: Interferon Signaling See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-399721 R-HSA-399721 Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Muscle contraction Immune System Transport of small molecules Gene expression (Transcription) Neuronal System Cellular responses to stimuli Signal Transduction	R-HSA-416320 ( R-HSA-399719 ) R-HSA-416320 Reaction Name: Trafficking of GluR1-containing AMPA receptors See in Reactome R-HSA-427910 ( R-HSA-5578775; R-HSA-936837 ) R-HSA-427910 Reaction Name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen See in Reactome R-HSA-432162 ( R-HSA-438066 ) R-HSA-432162 Reaction Name: Unblocking of GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-432164 ( R-HSA-438066 ) R-HSA-432164 Reaction Name: Ca2+ influx into the post-synaptic cell See in Reactome R-HSA-432172 ( R-HSA-438066 ) R-HSA-432172 Reaction Name: Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor See in Reactome R-HSA-438037 ( R-HSA-438066 ) R-HSA-438037 Reaction Name: Membrane depolarization upon activation of Ca impermeable AMPA receptors See in Reactome R-HSA-442725 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-442725 Reaction Name: CaMKII binds activated calmodulin See in Reactome R-HSA-442732 ( R-HSA-442982 ) R-HSA-442732 Reaction Name: NMDA-activated RASGRF1 activates RAS See in Reactome R-HSA-442760 ( R-HSA-442982 ) R-HSA-442760 Reaction Name: Activation of RasGRF See in Reactome R-HSA-444792 ( R-HSA-111932; R-HSA-442729 ) R-HSA-444792 Reaction Name: Calmodulin-bound CaMKII-gamma enters the nucleus See in Reactome R-HSA-445367 ( R-HSA-9620244 ) R-HSA-445367 Reaction Name: CaMKII binds activated NMDA receptor See in Reactome R-HSA-5082387 ( R-HSA-3371571 ) R-HSA-5082387 Reaction Name: Phosphorylation of HSF1 at Ser230 induces transactivation See in Reactome R-HSA-5576895 ( R-HSA-5576892 ) R-HSA-5576895 Reaction Name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-9006992 ( R-HSA-9022692 ) R-HSA-9006992 Reaction Name: MECP2 is phosphorylated at S423 See in Reactome R-HSA-909552 ( R-HSA-877300 ) R-HSA-909552 Reaction Name: Phosphorylation of STAT1 at Ser727 See in Reactome R-HSA-9611368 ( R-HSA-9609736 ) R-HSA-9611368 Reaction Name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9614185 ( R-HSA-438066 ) R-HSA-9614185 Reaction Name: Mg2+ binds GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-9617326 ( R-HSA-9617324 ) R-HSA-9617326 Reaction Name: CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 See in Reactome R-HSA-9617583 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-9617583 Reaction Name: CaMKII autophosphorylates See in Reactome R-HSA-9618750 ( R-HSA-9620244 ) R-HSA-9618750 Reaction Name: CaMKII phosphorylates AMPA receptor See in Reactome R-HSA-9619449 ( R-HSA-9617324 ) R-HSA-9619449 Reaction Name: PPM1F dephosphorylates p-T286-CaMKII See in Reactome
MONDO:0032795	CAMK2G	Q13555	2.7.11.17	R-HSA-442729 R-HSA-442729 Reactome Name: CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde See in Reactome R-HSA-111932 R-HSA-111932 Reactome Name: CaMK IV-mediated phosphorylation of CREB See in Reactome R-HSA-9617324 R-HSA-9617324 Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission See in Reactome R-HSA-5576892 R-HSA-5576892 Reactome Name: Phase 0 - rapid depolarisation See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-399719 R-HSA-399719 Reactome Name: Trafficking of AMPA receptors See in Reactome R-HSA-877300 R-HSA-877300 Reactome Name: Interferon gamma signaling See in Reactome R-HSA-438066 R-HSA-438066 Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation See in Reactome R-HSA-442982 R-HSA-442982 Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-936837 R-HSA-936837 Reactome Name: Ion transport by P-type ATPases See in Reactome R-HSA-9609736 R-HSA-9609736 Reactome Name: Assembly and cell surface presentation of NMDA receptors See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-442742 R-HSA-442742 Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-913531 R-HSA-913531 Reactome Name: Interferon Signaling See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-399721 R-HSA-399721 Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Muscle contraction Immune System Transport of small molecules Gene expression (Transcription) Neuronal System Cellular responses to stimuli Signal Transduction	R-HSA-416320 ( R-HSA-399719 ) R-HSA-416320 Reaction Name: Trafficking of GluR1-containing AMPA receptors See in Reactome R-HSA-427910 ( R-HSA-5578775; R-HSA-936837 ) R-HSA-427910 Reaction Name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen See in Reactome R-HSA-432162 ( R-HSA-438066 ) R-HSA-432162 Reaction Name: Unblocking of GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-432164 ( R-HSA-438066 ) R-HSA-432164 Reaction Name: Ca2+ influx into the post-synaptic cell See in Reactome R-HSA-432172 ( R-HSA-438066 ) R-HSA-432172 Reaction Name: Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor See in Reactome R-HSA-438037 ( R-HSA-438066 ) R-HSA-438037 Reaction Name: Membrane depolarization upon activation of Ca impermeable AMPA receptors See in Reactome R-HSA-442725 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-442725 Reaction Name: CaMKII binds activated calmodulin See in Reactome R-HSA-442732 ( R-HSA-442982 ) R-HSA-442732 Reaction Name: NMDA-activated RASGRF1 activates RAS See in Reactome R-HSA-442760 ( R-HSA-442982 ) R-HSA-442760 Reaction Name: Activation of RasGRF See in Reactome R-HSA-444792 ( R-HSA-111932; R-HSA-442729 ) R-HSA-444792 Reaction Name: Calmodulin-bound CaMKII-gamma enters the nucleus See in Reactome R-HSA-445367 ( R-HSA-9620244 ) R-HSA-445367 Reaction Name: CaMKII binds activated NMDA receptor See in Reactome R-HSA-5082387 ( R-HSA-3371571 ) R-HSA-5082387 Reaction Name: Phosphorylation of HSF1 at Ser230 induces transactivation See in Reactome R-HSA-5576895 ( R-HSA-5576892 ) R-HSA-5576895 Reaction Name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-9006992 ( R-HSA-9022692 ) R-HSA-9006992 Reaction Name: MECP2 is phosphorylated at S423 See in Reactome R-HSA-909552 ( R-HSA-877300 ) R-HSA-909552 Reaction Name: Phosphorylation of STAT1 at Ser727 See in Reactome R-HSA-9611368 ( R-HSA-9609736 ) R-HSA-9611368 Reaction Name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9614185 ( R-HSA-438066 ) R-HSA-9614185 Reaction Name: Mg2+ binds GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-9617326 ( R-HSA-9617324 ) R-HSA-9617326 Reaction Name: CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 See in Reactome R-HSA-9617583 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-9617583 Reaction Name: CaMKII autophosphorylates See in Reactome R-HSA-9618750 ( R-HSA-9620244 ) R-HSA-9618750 Reaction Name: CaMKII phosphorylates AMPA receptor See in Reactome R-HSA-9618834 ( R-HSA-111932; R-HSA-442729 ) R-HSA-9618834 Reaction Name: Activated calmodulin dissociates from CaMKII-gamma See in Reactome R-HSA-9619449 ( R-HSA-9617324 ) R-HSA-9619449 Reaction Name: PPM1F dephosphorylates p-T286-CaMKII See in Reactome
MONDO:0044903	SRC	P12931	2.7.10.2	R-HSA-418886 R-HSA-418886 Reactome Name: Netrin mediated repulsion signals See in Reactome R-HSA-171007 R-HSA-171007 Reactome Name: p38MAPK events See in Reactome R-HSA-428542 R-HSA-428542 Reactome Name: Regulation of commissural axon pathfinding by SLIT and ROBO See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-8940973 R-HSA-8940973 Reactome Name: RUNX2 regulates osteoblast differentiation See in Reactome R-HSA-418885 R-HSA-418885 Reactome Name: DCC mediated attractive signaling See in Reactome R-HSA-437239 R-HSA-437239 Reactome Name: Recycling pathway of L1 See in Reactome R-HSA-418592 R-HSA-418592 Reactome Name: ADP signalling through P2Y purinoceptor 1 See in Reactome R-HSA-430116 R-HSA-430116 Reactome Name: GP1b-IX-V activation signalling See in Reactome R-HSA-5663220 R-HSA-5663220 Reactome Name: RHO GTPases Activate Formins See in Reactome R-HSA-186763 R-HSA-186763 Reactome Name: Downstream signal transduction See in Reactome R-HSA-180292 R-HSA-180292 Reactome Name: GAB1 signalosome See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-3928662 R-HSA-3928662 Reactome Name: EPHB-mediated forward signaling See in Reactome R-HSA-418555 R-HSA-418555 Reactome Name: G alpha (s) signalling events See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-9032500 R-HSA-9032500 Reactome Name: Activated NTRK2 signals through FYN See in Reactome R-HSA-1257604 R-HSA-1257604 Reactome Name: PIP3 activates AKT signaling See in Reactome R-HSA-389513 R-HSA-389513 Reactome Name: CTLA4 inhibitory signaling See in Reactome R-HSA-8934903 R-HSA-8934903 Reactome Name: Receptor Mediated Mitophagy See in Reactome R-HSA-8853659 R-HSA-8853659 Reactome Name: RET signaling See in Reactome R-HSA-372708 R-HSA-372708 Reactome Name: p130Cas linkage to MAPK signaling for integrins See in Reactome R-HSA-389356 R-HSA-389356 Reactome Name: CD28 co-stimulation See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-391160 R-HSA-391160 Reactome Name: Signal regulatory protein family interactions See in Reactome R-HSA-4420097 R-HSA-4420097 Reactome Name: VEGFA-VEGFR2 Pathway See in Reactome R-HSA-1433559 R-HSA-1433559 Reactome Name: Regulation of KIT signaling See in Reactome R-HSA-2029481 R-HSA-2029481 Reactome Name: FCGR activation See in Reactome R-HSA-1295596 R-HSA-1295596 Reactome Name: Spry regulation of FGF signaling See in Reactome R-HSA-8934593 R-HSA-8934593 Reactome Name: Regulation of RUNX1 Expression and Activity See in Reactome R-HSA-1433557 R-HSA-1433557 Reactome Name: Signaling by SCF-KIT See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-375165 R-HSA-375165 Reactome Name: NCAM signaling for neurite out-growth See in Reactome R-HSA-5607764 R-HSA-5607764 Reactome Name: CLEC7A (Dectin-1) signaling See in Reactome R-HSA-5674135 R-HSA-5674135 Reactome Name: MAP2K and MAPK activation See in Reactome R-HSA-8874081 R-HSA-8874081 Reactome Name: MET activates PTK2 signaling See in Reactome R-HSA-1253288 R-HSA-1253288 Reactome Name: Downregulation of ERBB4 signaling See in Reactome R-HSA-2682334 R-HSA-2682334 Reactome Name: EPH-Ephrin signaling See in Reactome R-HSA-9009391 R-HSA-9009391 Reactome Name: Extra-nuclear estrogen signaling See in Reactome R-HSA-177929 R-HSA-177929 Reactome Name: Signaling by EGFR See in Reactome R-HSA-1251985 R-HSA-1251985 Reactome Name: Nuclear signaling by ERBB4 See in Reactome R-HSA-9603381 R-HSA-9603381 Reactome Name: Activated NTRK3 signals through PI3K See in Reactome R-HSA-354194 R-HSA-354194 Reactome Name: GRB2:SOS provides linkage to MAPK signaling for Integrins See in Reactome R-HSA-3928664 R-HSA-3928664 Reactome Name: Ephrin signaling See in Reactome R-HSA-456926 R-HSA-456926 Reactome Name: Thrombin signalling through proteinase activated receptors (PARs) See in Reactome R-HSA-354192 R-HSA-354192 Reactome Name: Integrin signaling See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-3928665 R-HSA-3928665 Reactome Name: EPH-ephrin mediated repulsion of cells See in Reactome R-HSA-191650 R-HSA-191650 Reactome Name: Regulation of gap junction activity See in Reactome R-HSA-9013420 R-HSA-9013420 Reactome Name: RHOU GTPase cycle See in Reactome R-HSA-6811558 R-HSA-6811558 Reactome Name: PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling See in Reactome R-HSA-210990 R-HSA-210990 Reactome Name: PECAM1 interactions See in Reactome R-HSA-1227986 R-HSA-1227986 Reactome Name: Signaling by ERBB2 See in Reactome R-HSA-5218921 R-HSA-5218921 Reactome Name: VEGFR2 mediated cell proliferation See in Reactome R-HSA-3928663 R-HSA-3928663 Reactome Name: EPHA-mediated growth cone collapse See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-376176 R-HSA-376176 Reactome Name: Signaling by ROBO receptors See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-8941326 R-HSA-8941326 Reactome Name: RUNX2 regulates bone development See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-202733 R-HSA-202733 Reactome Name: Cell surface interactions at the vascular wall See in Reactome R-HSA-1500931 R-HSA-1500931 Reactome Name: Cell-Cell communication See in Reactome R-HSA-195258 R-HSA-195258 Reactome Name: RHO GTPase Effectors See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-373760 R-HSA-373760 Reactome Name: L1CAM interactions See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome R-HSA-76009 R-HSA-76009 Reactome Name: Platelet Aggregation (Plug Formation) See in Reactome R-HSA-9612973 R-HSA-9612973 Reactome Name: Autophagy See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome R-HSA-388841 R-HSA-388841 Reactome Name: Costimulation by the CD28 family See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-5654726 R-HSA-5654726 Reactome Name: Negative regulation of FGFR1 signaling See in Reactome R-HSA-5654727 R-HSA-5654727 Reactome Name: Negative regulation of FGFR2 signaling See in Reactome R-HSA-199418 R-HSA-199418 Reactome Name: Negative regulation of the PI3K/AKT network See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-5205647 R-HSA-5205647 Reactome Name: Mitophagy See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-8875878 R-HSA-8875878 Reactome Name: MET promotes cell motility See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5654743 R-HSA-5654743 Reactome Name: Signaling by FGFR4 See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-190236 R-HSA-190236 Reactome Name: Signaling by FGFR See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-9663891 R-HSA-9663891 Reactome Name: Selective autophagy See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-392518 R-HSA-392518 Reactome Name: Signal amplification See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-157858 R-HSA-157858 Reactome Name: Gap junction trafficking and regulation See in Reactome R-HSA-9006115 R-HSA-9006115 Reactome Name: Signaling by NTRK2 (TRKB) See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-1236394 R-HSA-1236394 Reactome Name: Signaling by ERBB4 See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome R-HSA-1632852 R-HSA-1632852 Reactome Name: Macroautophagy See in Reactome R-HSA-6806834 R-HSA-6806834 Reactome Name: Signaling by MET See in Reactome R-HSA-187687 R-HSA-187687 Reactome Name: Signalling to ERKs See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-5654738 R-HSA-5654738 Reactome Name: Signaling by FGFR2 See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5654736 R-HSA-5654736 Reactome Name: Signaling by FGFR1 See in Reactome R-HSA-5654733 R-HSA-5654733 Reactome Name: Negative regulation of FGFR4 signaling See in Reactome R-HSA-5654732 R-HSA-5654732 Reactome Name: Negative regulation of FGFR3 signaling See in Reactome R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-9034015 R-HSA-9034015 Reactome Name: Signaling by NTRK3 (TRKC) See in Reactome R-HSA-186797 R-HSA-186797 Reactome Name: Signaling by PDGF See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-5654741 R-HSA-5654741 Reactome Name: Signaling by FGFR3 See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-167044 R-HSA-167044 Reactome Name: Signalling to RAS See in Reactome R-HSA-373752 R-HSA-373752 Reactome Name: Netrin-1 signaling See in Reactome	Immune System Cell-Cell communication Cell Cycle Developmental Biology Autophagy Gene expression (Transcription) Neuronal System Signal Transduction Vesicle-mediated transport Hemostasis	R-HSA-1252013 ( R-HSA-1236394; R-HSA-1251985 ) R-HSA-1252013 Reaction Name: Translocation of ERBB4s80 to the nucleus See in Reactome R-HSA-177923 ( R-HSA-177929; R-HSA-180292 ) R-HSA-177923 Reaction Name: Sustained activation of SRC kinase by SHP2 See in Reactome R-HSA-186819 ( R-HSA-186763 ) R-HSA-186819 Reaction Name: SH2 domain of Src binds to the active receptor See in Reactome R-HSA-1963586 ( R-HSA-1227986 ) R-HSA-1963586 Reaction Name: SRC family kinases phosphorylate ERBB2 See in Reactome R-HSA-2316434 ( R-HSA-1257604; R-HSA-6811558 ) R-HSA-2316434 Reaction Name: PI3K phosphorylates PIP2 to PIP3 See in Reactome R-HSA-354066 ( R-HSA-354192 ) R-HSA-354066 Reaction Name: Translocation of PTK2 to Focal complexes See in Reactome R-HSA-354073 ( R-HSA-354192 ) R-HSA-354073 Reaction Name: Autophosphorylation of PTK2 at Y397 See in Reactome R-HSA-354077 ( R-HSA-354192 ) R-HSA-354077 Reaction Name: Integrin alphaIIb beta3 activation See in Reactome R-HSA-354087 ( R-HSA-354192; R-HSA-354194 ) R-HSA-354087 Reaction Name: Recruitment of GRB2 to p-PTK2 See in Reactome R-HSA-354124 ( R-HSA-354192 ) R-HSA-354124 Reaction Name: Phosphorylation of pPTK2 by SRC See in Reactome R-HSA-354149 ( R-HSA-354192 ) R-HSA-354149 Reaction Name: Interaction of integrin alphaIIb beta3 with Fibrinogen See in Reactome R-HSA-354165 ( R-HSA-354192; R-HSA-354194 ) R-HSA-354165 Reaction Name: Interaction of SOS with GRB2 bound to FADK1 See in Reactome R-HSA-372693 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372693 Reaction Name: Phosphorylation of BCAR1 by SRC-PTK2 complex See in Reactome R-HSA-372697 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372697 Reaction Name: Crk binding to p130cas See in Reactome R-HSA-372705 ( R-HSA-354192; R-HSA-372708 ) R-HSA-372705 Reaction Name: Recruitment of BCAR1 to PTK2 complex See in Reactome R-HSA-373716 ( R-HSA-418885 ) R-HSA-373716 Reaction Name: DCC interacting NCK-1 See in Reactome R-HSA-374701 ( R-HSA-418885 ) R-HSA-374701 Reaction Name: Phosphorylation of DCC by Fyn See in Reactome R-HSA-377640 ( R-HSA-354192 ) R-HSA-377640 Reaction Name: Autophosphorylation of SRC See in Reactome R-HSA-377641 ( R-HSA-354192 ) R-HSA-377641 Reaction Name: Clustering of Integrin alphaIIb beta3 complexes See in Reactome R-HSA-377643 ( R-HSA-354192 ) R-HSA-377643 Reaction Name: Dephosphorylation of inactive SRC by PTPB1 See in Reactome R-HSA-377644 ( R-HSA-354192 ) R-HSA-377644 Reaction Name: Release of CSK from SRC See in Reactome R-HSA-380780 ( R-HSA-186763 ) R-HSA-380780 Reaction Name: Activation of Src See in Reactome R-HSA-418850 ( R-HSA-418885 ) R-HSA-418850 Reaction Name: Activation of Cdc42 See in Reactome R-HSA-418856 ( R-HSA-418885 ) R-HSA-418856 Reaction Name: Activation of Rac1 See in Reactome R-HSA-418858 ( R-HSA-418885 ) R-HSA-418858 Reaction Name: RhoGTPase GEF's recruited to DCC See in Reactome R-HSA-418859 ( R-HSA-418886 ) R-HSA-418859 Reaction Name: Phosphorylation of Unc5C See in Reactome R-HSA-418865 ( R-HSA-418885 ) R-HSA-418865 Reaction Name: Recruitment of ABLIM to the plasma membrane See in Reactome R-HSA-418868 ( R-HSA-418885 ) R-HSA-418868 Reaction Name: Recruitment of Src and Fyn to DCC:FADK1 See in Reactome R-HSA-418874 ( R-HSA-418885 ) R-HSA-418874 Reaction Name: Recruitment and activation of N-WASP by Cdc42 See in Reactome R-HSA-429415 ( R-HSA-354192 ) R-HSA-429415 Reaction Name: SYK binds to integrin alphaIIb beta3 See in Reactome R-HSA-429441 ( R-HSA-354192 ) R-HSA-429441 Reaction Name: SYK activation by SRC See in Reactome R-HSA-432096 ( R-HSA-354192 ) R-HSA-432096 Reaction Name: Activated integrin alphaIIb beta3 binds SHC1 See in Reactome R-HSA-443905 ( R-HSA-354192 ) R-HSA-443905 Reaction Name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow See in Reactome R-HSA-443910 ( R-HSA-354192 ) R-HSA-443910 Reaction Name: SHC1 dissociates from integrin alphaIIb beta3 See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-5672972 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672972 Reaction Name: MAP2Ks and MAPKs bind to the activated RAF complex See in Reactome R-HSA-5672973 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672973 Reaction Name: MAP2Ks phosphorylate MAPKs See in Reactome R-HSA-5672978 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672978 Reaction Name: RAF phosphorylates MAP2K dimer See in Reactome R-HSA-5672980 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-5672980 Reaction Name: Dissociation of RAS:RAF complex See in Reactome R-HSA-8874080 ( R-HSA-8874081 ) R-HSA-8874080 Reaction Name: SRC phosphorylates PTK2 See in Reactome R-HSA-8874082 ( R-HSA-8874081 ) R-HSA-8874082 Reaction Name: MET phosphorylates PTK2 See in Reactome R-HSA-8874083 ( R-HSA-8874081 ) R-HSA-8874083 Reaction Name: p-Y397-PTK2 binds SRC See in Reactome R-HSA-8937682 ( R-HSA-8934593 ) R-HSA-8937682 Reaction Name: RUNX1 binds SRC See in Reactome R-HSA-8937728 ( R-HSA-8934593 ) R-HSA-8937728 Reaction Name: SRC phosphorylates RUNX1 See in Reactome R-HSA-8937792 ( R-HSA-8941858 ) R-HSA-8937792 Reaction Name: RUNX3 binds SRC See in Reactome R-HSA-8937807 ( R-HSA-8941858 ) R-HSA-8937807 Reaction Name: SRC phosphorylates RUNX3 See in Reactome R-HSA-8937814 ( R-HSA-8941858 ) R-HSA-8937814 Reaction Name: RUNX3 translocates to the nucleus See in Reactome R-HSA-8937820 ( R-HSA-8940973 ) R-HSA-8937820 Reaction Name: SRC,YES1 bind YAP1 See in Reactome R-HSA-8937844 ( R-HSA-8940973 ) R-HSA-8937844 Reaction Name: SRC,YES1 phosphorylate YAP1 See in Reactome R-HSA-8964242 ( R-HSA-418594 ) R-HSA-8964242 Reaction Name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC See in Reactome R-HSA-8964252 ( R-HSA-418555 ) R-HSA-8964252 Reaction Name: G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC See in Reactome R-HSA-8964278 ( R-HSA-418555 ) R-HSA-8964278 Reaction Name: G protein alpha (s):GTP binds SRC See in Reactome R-HSA-8964287 ( R-HSA-418555 ) R-HSA-8964287 Reaction Name: G alpha (s):GTP:SRC dissociates See in Reactome R-HSA-8964311 ( R-HSA-418594 ) R-HSA-8964311 Reaction Name: G alpha (i):GTP binds SRC See in Reactome R-HSA-8964329 ( R-HSA-418594 ) R-HSA-8964329 Reaction Name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC See in Reactome R-HSA-9011241 ( R-HSA-428542 ) R-HSA-9011241 Reaction Name: SRC phosphorylates ROBO3.1 in response to NTN1 See in Reactome R-HSA-9021596 ( R-HSA-9009391 ) R-HSA-9021596 Reaction Name: Membrane estrogen receptors bind SRC See in Reactome R-HSA-9021609 ( R-HSA-9009391 ) R-HSA-9021609 Reaction Name: ESR-associated SRC autophosphorylates See in Reactome R-HSA-9021660 ( R-HSA-9009391 ) R-HSA-9021660 Reaction Name: PI3K binds membrane-associated estrogen receptors See in Reactome R-HSA-9037040 ( R-HSA-9032500 ) R-HSA-9037040 Reaction Name: SRC,FYN phosphorylate NTRK2 See in Reactome R-HSA-9603419 ( R-HSA-9603381 ) R-HSA-9603419 Reaction Name: Activated NTRK3 binds SRC See in Reactome R-HSA-9603420 ( R-HSA-9603381 ) R-HSA-9603420 Reaction Name: Activated NTRK3 promotes SRC autophosphorylation See in Reactome R-HSA-9603437 ( R-HSA-9603381 ) R-HSA-9603437 Reaction Name: Activated NTRK3 binds IRS1 See in Reactome R-HSA-9603445 ( R-HSA-9603381 ) R-HSA-9603445 Reaction Name: Activated NTRK3 stimulates PI3K activity See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9612219 ( R-HSA-1236394; R-HSA-1253288 ) R-HSA-9612219 Reaction Name: ERBB4s80 binds to SRC See in Reactome R-HSA-9624014 ( R-HSA-418555 ) R-HSA-9624014 Reaction Name: SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 See in Reactome R-HSA-9632412 ( R-HSA-9009391 ) R-HSA-9632412 Reaction Name: PTK2 is recruited to methylated ESR1 See in Reactome R-HSA-9657599 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657599 Reaction Name: Dual mechanism MAP2K inhibitors bind MAP2Ks See in Reactome R-HSA-9657603 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657603 Reaction Name: Dual mechanism MAPK inhibitors bind MAPKs See in Reactome R-HSA-9657606 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657606 Reaction Name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks See in Reactome R-HSA-9657608 ( R-HSA-5673001; R-HSA-5674135 ) R-HSA-9657608 Reaction Name: Single mechanism MAPK inhibitors bind phosphorylated MAPK See in Reactome R-HSA-9726848 ( R-HSA-9013420 ) R-HSA-9726848 Reaction Name: SRC phosphorylates RHOU See in Reactome
MONDO:0054861	CAMK2A	Q9UQM7	2.7.11.17	R-HSA-111932 R-HSA-111932 Reactome Name: CaMK IV-mediated phosphorylation of CREB See in Reactome R-HSA-9617324 R-HSA-9617324 Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission See in Reactome R-HSA-5576892 R-HSA-5576892 Reactome Name: Phase 0 - rapid depolarisation See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-399719 R-HSA-399719 Reactome Name: Trafficking of AMPA receptors See in Reactome R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-877300 R-HSA-877300 Reactome Name: Interferon gamma signaling See in Reactome R-HSA-438066 R-HSA-438066 Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation See in Reactome R-HSA-442982 R-HSA-442982 Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-936837 R-HSA-936837 Reactome Name: Ion transport by P-type ATPases See in Reactome R-HSA-9609736 R-HSA-9609736 Reactome Name: Assembly and cell surface presentation of NMDA receptors See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-442742 R-HSA-442742 Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-913531 R-HSA-913531 Reactome Name: Interferon Signaling See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-399721 R-HSA-399721 Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Muscle contraction Immune System Transport of small molecules Gene expression (Transcription) Neuronal System Cellular responses to stimuli Signal Transduction	R-HSA-416320 ( R-HSA-399719 ) R-HSA-416320 Reaction Name: Trafficking of GluR1-containing AMPA receptors See in Reactome R-HSA-427910 ( R-HSA-5578775; R-HSA-936837 ) R-HSA-427910 Reaction Name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen See in Reactome R-HSA-432162 ( R-HSA-438066 ) R-HSA-432162 Reaction Name: Unblocking of GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-432164 ( R-HSA-438066 ) R-HSA-432164 Reaction Name: Ca2+ influx into the post-synaptic cell See in Reactome R-HSA-432172 ( R-HSA-438066 ) R-HSA-432172 Reaction Name: Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor See in Reactome R-HSA-4332356 ( R-HSA-4086398 ) R-HSA-4332356 Reaction Name: CAMK2 binds MAP3K7 See in Reactome R-HSA-4332358 ( R-HSA-4086398 ) R-HSA-4332358 Reaction Name: Dissociation of CaM and CAMK2 autophosphorylation See in Reactome R-HSA-4332359 ( R-HSA-4086398 ) R-HSA-4332359 Reaction Name: Active calmodulin binds CAMK2 See in Reactome R-HSA-4332363 ( R-HSA-4086398 ) R-HSA-4332363 Reaction Name: Autophosphorylation and activation of CAMK2 See in Reactome R-HSA-4332388 ( R-HSA-4086398 ) R-HSA-4332388 Reaction Name: Activation of MAP3K7 in response to WNT See in Reactome R-HSA-438037 ( R-HSA-438066 ) R-HSA-438037 Reaction Name: Membrane depolarization upon activation of Ca impermeable AMPA receptors See in Reactome R-HSA-442725 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-442725 Reaction Name: CaMKII binds activated calmodulin See in Reactome R-HSA-442732 ( R-HSA-442982 ) R-HSA-442732 Reaction Name: NMDA-activated RASGRF1 activates RAS See in Reactome R-HSA-442760 ( R-HSA-442982 ) R-HSA-442760 Reaction Name: Activation of RasGRF See in Reactome R-HSA-445367 ( R-HSA-9620244 ) R-HSA-445367 Reaction Name: CaMKII binds activated NMDA receptor See in Reactome R-HSA-5082387 ( R-HSA-3371571 ) R-HSA-5082387 Reaction Name: Phosphorylation of HSF1 at Ser230 induces transactivation See in Reactome R-HSA-5576895 ( R-HSA-5576892 ) R-HSA-5576895 Reaction Name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-9006992 ( R-HSA-9022692 ) R-HSA-9006992 Reaction Name: MECP2 is phosphorylated at S423 See in Reactome R-HSA-909552 ( R-HSA-877300 ) R-HSA-909552 Reaction Name: Phosphorylation of STAT1 at Ser727 See in Reactome R-HSA-9611368 ( R-HSA-9609736 ) R-HSA-9611368 Reaction Name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9614185 ( R-HSA-438066 ) R-HSA-9614185 Reaction Name: Mg2+ binds GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-9617326 ( R-HSA-9617324 ) R-HSA-9617326 Reaction Name: CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 See in Reactome R-HSA-9617583 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-9617583 Reaction Name: CaMKII autophosphorylates See in Reactome R-HSA-9618750 ( R-HSA-9620244 ) R-HSA-9618750 Reaction Name: CaMKII phosphorylates AMPA receptor See in Reactome R-HSA-9619449 ( R-HSA-9617324 ) R-HSA-9619449 Reaction Name: PPM1F dephosphorylates p-T286-CaMKII See in Reactome