DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-9619665)

Number of enzymes:	5
Number of disease:	14
Number of reactomes:	13
Number of reactions:	47

Search results (Reactome ID: R-HSA-9619665)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0003795	SMARCA4	P51532	3.6.4.-	R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-1266695 R-HSA-1266695 Reactome Name: Interleukin-7 signaling See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System Chromatin organization Signal Transduction Developmental Biology	R-HSA-3215448 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-3215448 Reaction Name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity See in Reactome R-HSA-3322422 ( R-HSA-201722 ) R-HSA-3322422 Reaction Name: Beta-catenin recruits SMARCA4 See in Reactome R-HSA-5205799 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-8865605 ( R-HSA-1266695; R-HSA-3247509 ) R-HSA-8865605 Reaction Name: BRWD1 binds SMARCA4 See in Reactome R-HSA-8938217 ( R-HSA-8939243 ) R-HSA-8938217 Reaction Name: RUNX1 binds the SWI/SNF complex See in Reactome R-HSA-9613644 ( R-HSA-9619665 ) R-HSA-9613644 Reaction Name: SOX10-dependent POU3F1 gene expression See in Reactome R-HSA-9613648 ( R-HSA-9619665 ) R-HSA-9613648 Reaction Name: SOX10 dimer binds the POU3F1 promoter See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome
MONDO:0007790	EGR2	P11161	2.3.2.-	R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Developmental Biology Signal Transduction	R-HSA-381337 ( R-HSA-381340 ) R-HSA-381337 Reaction Name: Expression of CEBPB in adipogenesis See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-5617483 ( R-HSA-5617472 ) R-HSA-5617483 Reaction Name: HOXA2 gene is transcribed See in Reactome R-HSA-5617484 ( R-HSA-5617472 ) R-HSA-5617484 Reaction Name: EGR2 (KROX20) activates HOXA2 expression See in Reactome R-HSA-5617486 ( R-HSA-5617472 ) R-HSA-5617486 Reaction Name: HOXB2 gene is transcribed See in Reactome R-HSA-5617492 ( R-HSA-5617472 ) R-HSA-5617492 Reaction Name: EGR2 (KROX20) activates HOXB2 expression See in Reactome R-HSA-5617661 ( R-HSA-5617472 ) R-HSA-5617661 Reaction Name: MAFB:JUN and EGR2 activate HOXB3 expression See in Reactome R-HSA-5617672 ( R-HSA-5617472 ) R-HSA-5617672 Reaction Name: HOXB3 gene is transcribed See in Reactome R-HSA-9031616 ( R-HSA-9031628 ) R-HSA-9031616 Reaction Name: EGR binds ARC gene See in Reactome R-HSA-9031624 ( R-HSA-9031628 ) R-HSA-9031624 Reaction Name: ARC gene expression See in Reactome R-HSA-9612073 ( R-HSA-9031628 ) R-HSA-9612073 Reaction Name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression See in Reactome R-HSA-9612483 ( R-HSA-9031628 ) R-HSA-9612483 Reaction Name: EGR1,2,3 bind the NAB2 promoter See in Reactome R-HSA-9612493 ( R-HSA-9031628 ) R-HSA-9612493 Reaction Name: EGR-dependent NAB2 gene expression See in Reactome R-HSA-9612534 ( R-HSA-9031628 ) R-HSA-9612534 Reaction Name: Expression of ID2 and ID4 is repressed by EGR2:NAB See in Reactome R-HSA-9613210 ( R-HSA-9031628 ) R-HSA-9613210 Reaction Name: EGR1, EGR2 bind the RRAD promoter See in Reactome R-HSA-9613213 ( R-HSA-9031628 ) R-HSA-9613213 Reaction Name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression See in Reactome R-HSA-9613219 ( R-HSA-9031628 ) R-HSA-9613219 Reaction Name: RRAD gene expression See in Reactome R-HSA-9613476 ( R-HSA-9031628 ) R-HSA-9613476 Reaction Name: EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions See in Reactome R-HSA-9613760 ( R-HSA-9619665 ) R-HSA-9613760 Reaction Name: EGR2 gene expression See in Reactome R-HSA-9614773 ( R-HSA-9619665 ) R-HSA-9614773 Reaction Name: MBP gene expression See in Reactome R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome R-HSA-9615626 ( R-HSA-9619665 ) R-HSA-9615626 Reaction Name: PMP22 gene expression See in Reactome R-HSA-9615638 ( R-HSA-9619665 ) R-HSA-9615638 Reaction Name: EGR2 and SOX10 bind the MBP gene See in Reactome R-HSA-9616116 ( R-HSA-9619665 ) R-HSA-9616116 Reaction Name: EGR2 and SOX10 bind the MAG gene See in Reactome R-HSA-9618559 ( R-HSA-9619665 ) R-HSA-9618559 Reaction Name: EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene See in Reactome R-HSA-9618725 ( R-HSA-9619665 ) R-HSA-9618725 Reaction Name: SOX10, EGR2 and NAB proteins bind the GJB1 promoter See in Reactome R-HSA-9619657 ( R-HSA-9619665 ) R-HSA-9619657 Reaction Name: EGR2 and SOX10 bind the PRX gene See in Reactome R-HSA-9619667 ( R-HSA-9619665 ) R-HSA-9619667 Reaction Name: PRX gene expression See in Reactome R-HSA-9621399 ( R-HSA-9619665 ) R-HSA-9621399 Reaction Name: SCD5 gene expression See in Reactome R-HSA-9621400 ( R-HSA-9619665 ) R-HSA-9621400 Reaction Name: EGR2 and SREBF2 dimer bind SCD5 gene See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome R-HSA-9621406 ( R-HSA-9619665 ) R-HSA-9621406 Reaction Name: EGR2 and SREBF2 dimer bind CYP51A1 gene See in Reactome R-HSA-9621410 ( R-HSA-9619665 ) R-HSA-9621410 Reaction Name: HMGCR gene expression See in Reactome R-HSA-9621411 ( R-HSA-9619665 ) R-HSA-9621411 Reaction Name: EGR2 and SREBF2(1-484) dimer bind HMGCR gene See in Reactome
MONDO:0010168	ADGRV1	Q8WXG9	3.4.-.-	R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Developmental Biology	R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome
MONDO:0011443	ADGRV1	Q8WXG9	3.4.-.-	R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Developmental Biology	R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome
MONDO:0011527	EGR2	P11161	2.3.2.-	R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Developmental Biology Signal Transduction	R-HSA-381337 ( R-HSA-381340 ) R-HSA-381337 Reaction Name: Expression of CEBPB in adipogenesis See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-5617483 ( R-HSA-5617472 ) R-HSA-5617483 Reaction Name: HOXA2 gene is transcribed See in Reactome R-HSA-5617484 ( R-HSA-5617472 ) R-HSA-5617484 Reaction Name: EGR2 (KROX20) activates HOXA2 expression See in Reactome R-HSA-5617486 ( R-HSA-5617472 ) R-HSA-5617486 Reaction Name: HOXB2 gene is transcribed See in Reactome R-HSA-5617492 ( R-HSA-5617472 ) R-HSA-5617492 Reaction Name: EGR2 (KROX20) activates HOXB2 expression See in Reactome R-HSA-5617661 ( R-HSA-5617472 ) R-HSA-5617661 Reaction Name: MAFB:JUN and EGR2 activate HOXB3 expression See in Reactome R-HSA-5617672 ( R-HSA-5617472 ) R-HSA-5617672 Reaction Name: HOXB3 gene is transcribed See in Reactome R-HSA-9031616 ( R-HSA-9031628 ) R-HSA-9031616 Reaction Name: EGR binds ARC gene See in Reactome R-HSA-9031624 ( R-HSA-9031628 ) R-HSA-9031624 Reaction Name: ARC gene expression See in Reactome R-HSA-9612073 ( R-HSA-9031628 ) R-HSA-9612073 Reaction Name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression See in Reactome R-HSA-9612483 ( R-HSA-9031628 ) R-HSA-9612483 Reaction Name: EGR1,2,3 bind the NAB2 promoter See in Reactome R-HSA-9612493 ( R-HSA-9031628 ) R-HSA-9612493 Reaction Name: EGR-dependent NAB2 gene expression See in Reactome R-HSA-9612534 ( R-HSA-9031628 ) R-HSA-9612534 Reaction Name: Expression of ID2 and ID4 is repressed by EGR2:NAB See in Reactome R-HSA-9613210 ( R-HSA-9031628 ) R-HSA-9613210 Reaction Name: EGR1, EGR2 bind the RRAD promoter See in Reactome R-HSA-9613213 ( R-HSA-9031628 ) R-HSA-9613213 Reaction Name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression See in Reactome R-HSA-9613219 ( R-HSA-9031628 ) R-HSA-9613219 Reaction Name: RRAD gene expression See in Reactome R-HSA-9613476 ( R-HSA-9031628 ) R-HSA-9613476 Reaction Name: EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions See in Reactome R-HSA-9613760 ( R-HSA-9619665 ) R-HSA-9613760 Reaction Name: EGR2 gene expression See in Reactome R-HSA-9614773 ( R-HSA-9619665 ) R-HSA-9614773 Reaction Name: MBP gene expression See in Reactome R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome R-HSA-9615626 ( R-HSA-9619665 ) R-HSA-9615626 Reaction Name: PMP22 gene expression See in Reactome R-HSA-9615638 ( R-HSA-9619665 ) R-HSA-9615638 Reaction Name: EGR2 and SOX10 bind the MBP gene See in Reactome R-HSA-9616116 ( R-HSA-9619665 ) R-HSA-9616116 Reaction Name: EGR2 and SOX10 bind the MAG gene See in Reactome R-HSA-9618559 ( R-HSA-9619665 ) R-HSA-9618559 Reaction Name: EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene See in Reactome R-HSA-9618725 ( R-HSA-9619665 ) R-HSA-9618725 Reaction Name: SOX10, EGR2 and NAB proteins bind the GJB1 promoter See in Reactome R-HSA-9619657 ( R-HSA-9619665 ) R-HSA-9619657 Reaction Name: EGR2 and SOX10 bind the PRX gene See in Reactome R-HSA-9619667 ( R-HSA-9619665 ) R-HSA-9619667 Reaction Name: PRX gene expression See in Reactome R-HSA-9621399 ( R-HSA-9619665 ) R-HSA-9621399 Reaction Name: SCD5 gene expression See in Reactome R-HSA-9621400 ( R-HSA-9619665 ) R-HSA-9621400 Reaction Name: EGR2 and SREBF2 dimer bind SCD5 gene See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome R-HSA-9621406 ( R-HSA-9619665 ) R-HSA-9621406 Reaction Name: EGR2 and SREBF2 dimer bind CYP51A1 gene See in Reactome R-HSA-9621410 ( R-HSA-9619665 ) R-HSA-9621410 Reaction Name: HMGCR gene expression See in Reactome R-HSA-9621411 ( R-HSA-9619665 ) R-HSA-9621411 Reaction Name: EGR2 and SREBF2(1-484) dimer bind HMGCR gene See in Reactome
MONDO:0011558	ADGRV1	Q8WXG9	3.4.-.-	R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Developmental Biology	R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome
MONDO:0011890	EGR2	P11161	2.3.2.-	R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Developmental Biology Signal Transduction	R-HSA-381337 ( R-HSA-381340 ) R-HSA-381337 Reaction Name: Expression of CEBPB in adipogenesis See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-5617483 ( R-HSA-5617472 ) R-HSA-5617483 Reaction Name: HOXA2 gene is transcribed See in Reactome R-HSA-5617484 ( R-HSA-5617472 ) R-HSA-5617484 Reaction Name: EGR2 (KROX20) activates HOXA2 expression See in Reactome R-HSA-5617486 ( R-HSA-5617472 ) R-HSA-5617486 Reaction Name: HOXB2 gene is transcribed See in Reactome R-HSA-5617492 ( R-HSA-5617472 ) R-HSA-5617492 Reaction Name: EGR2 (KROX20) activates HOXB2 expression See in Reactome R-HSA-5617661 ( R-HSA-5617472 ) R-HSA-5617661 Reaction Name: MAFB:JUN and EGR2 activate HOXB3 expression See in Reactome R-HSA-5617672 ( R-HSA-5617472 ) R-HSA-5617672 Reaction Name: HOXB3 gene is transcribed See in Reactome R-HSA-9031616 ( R-HSA-9031628 ) R-HSA-9031616 Reaction Name: EGR binds ARC gene See in Reactome R-HSA-9031624 ( R-HSA-9031628 ) R-HSA-9031624 Reaction Name: ARC gene expression See in Reactome R-HSA-9612073 ( R-HSA-9031628 ) R-HSA-9612073 Reaction Name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression See in Reactome R-HSA-9612483 ( R-HSA-9031628 ) R-HSA-9612483 Reaction Name: EGR1,2,3 bind the NAB2 promoter See in Reactome R-HSA-9612493 ( R-HSA-9031628 ) R-HSA-9612493 Reaction Name: EGR-dependent NAB2 gene expression See in Reactome R-HSA-9612534 ( R-HSA-9031628 ) R-HSA-9612534 Reaction Name: Expression of ID2 and ID4 is repressed by EGR2:NAB See in Reactome R-HSA-9613210 ( R-HSA-9031628 ) R-HSA-9613210 Reaction Name: EGR1, EGR2 bind the RRAD promoter See in Reactome R-HSA-9613213 ( R-HSA-9031628 ) R-HSA-9613213 Reaction Name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression See in Reactome R-HSA-9613219 ( R-HSA-9031628 ) R-HSA-9613219 Reaction Name: RRAD gene expression See in Reactome R-HSA-9613476 ( R-HSA-9031628 ) R-HSA-9613476 Reaction Name: EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions See in Reactome R-HSA-9613760 ( R-HSA-9619665 ) R-HSA-9613760 Reaction Name: EGR2 gene expression See in Reactome R-HSA-9614773 ( R-HSA-9619665 ) R-HSA-9614773 Reaction Name: MBP gene expression See in Reactome R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome R-HSA-9615626 ( R-HSA-9619665 ) R-HSA-9615626 Reaction Name: PMP22 gene expression See in Reactome R-HSA-9615638 ( R-HSA-9619665 ) R-HSA-9615638 Reaction Name: EGR2 and SOX10 bind the MBP gene See in Reactome R-HSA-9616116 ( R-HSA-9619665 ) R-HSA-9616116 Reaction Name: EGR2 and SOX10 bind the MAG gene See in Reactome R-HSA-9618559 ( R-HSA-9619665 ) R-HSA-9618559 Reaction Name: EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene See in Reactome R-HSA-9618725 ( R-HSA-9619665 ) R-HSA-9618725 Reaction Name: SOX10, EGR2 and NAB proteins bind the GJB1 promoter See in Reactome R-HSA-9619657 ( R-HSA-9619665 ) R-HSA-9619657 Reaction Name: EGR2 and SOX10 bind the PRX gene See in Reactome R-HSA-9619667 ( R-HSA-9619665 ) R-HSA-9619667 Reaction Name: PRX gene expression See in Reactome R-HSA-9621399 ( R-HSA-9619665 ) R-HSA-9621399 Reaction Name: SCD5 gene expression See in Reactome R-HSA-9621400 ( R-HSA-9619665 ) R-HSA-9621400 Reaction Name: EGR2 and SREBF2 dimer bind SCD5 gene See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome R-HSA-9621406 ( R-HSA-9619665 ) R-HSA-9621406 Reaction Name: EGR2 and SREBF2 dimer bind CYP51A1 gene See in Reactome R-HSA-9621410 ( R-HSA-9619665 ) R-HSA-9621410 Reaction Name: HMGCR gene expression See in Reactome R-HSA-9621411 ( R-HSA-9619665 ) R-HSA-9621411 Reaction Name: EGR2 and SREBF2(1-484) dimer bind HMGCR gene See in Reactome
MONDO:0013224	SMARCA4	P51532	3.6.4.-	R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-1266695 R-HSA-1266695 Reactome Name: Interleukin-7 signaling See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System Chromatin organization Signal Transduction Developmental Biology	R-HSA-3215448 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-3215448 Reaction Name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity See in Reactome R-HSA-3322422 ( R-HSA-201722 ) R-HSA-3322422 Reaction Name: Beta-catenin recruits SMARCA4 See in Reactome R-HSA-5205799 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-8865605 ( R-HSA-1266695; R-HSA-3247509 ) R-HSA-8865605 Reaction Name: BRWD1 binds SMARCA4 See in Reactome R-HSA-8938217 ( R-HSA-8939243 ) R-HSA-8938217 Reaction Name: RUNX1 binds the SWI/SNF complex See in Reactome R-HSA-9613644 ( R-HSA-9619665 ) R-HSA-9613644 Reaction Name: SOX10-dependent POU3F1 gene expression See in Reactome R-HSA-9613648 ( R-HSA-9619665 ) R-HSA-9613648 Reaction Name: SOX10 dimer binds the POU3F1 promoter See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome
MONDO:0013821	SMARCA4	P51532	3.6.4.-	R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-1266695 R-HSA-1266695 Reactome Name: Interleukin-7 signaling See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System Chromatin organization Signal Transduction Developmental Biology	R-HSA-3215448 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-3215448 Reaction Name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity See in Reactome R-HSA-3322422 ( R-HSA-201722 ) R-HSA-3322422 Reaction Name: Beta-catenin recruits SMARCA4 See in Reactome R-HSA-5205799 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-8865605 ( R-HSA-1266695; R-HSA-3247509 ) R-HSA-8865605 Reaction Name: BRWD1 binds SMARCA4 See in Reactome R-HSA-8938217 ( R-HSA-8939243 ) R-HSA-8938217 Reaction Name: RUNX1 binds the SWI/SNF complex See in Reactome R-HSA-9613644 ( R-HSA-9619665 ) R-HSA-9613644 Reaction Name: SOX10-dependent POU3F1 gene expression See in Reactome R-HSA-9613648 ( R-HSA-9619665 ) R-HSA-9613648 Reaction Name: SOX10 dimer binds the POU3F1 promoter See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome
MONDO:0018761	SMARCA4	P51532	3.6.4.-	R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-1266695 R-HSA-1266695 Reactome Name: Interleukin-7 signaling See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System Chromatin organization Signal Transduction Developmental Biology	R-HSA-3215448 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-3215448 Reaction Name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity See in Reactome R-HSA-3322422 ( R-HSA-201722 ) R-HSA-3322422 Reaction Name: Beta-catenin recruits SMARCA4 See in Reactome R-HSA-5205799 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858; R-HSA-3247509 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-8865605 ( R-HSA-1266695; R-HSA-3247509 ) R-HSA-8865605 Reaction Name: BRWD1 binds SMARCA4 See in Reactome R-HSA-8938217 ( R-HSA-8939243 ) R-HSA-8938217 Reaction Name: RUNX1 binds the SWI/SNF complex See in Reactome R-HSA-9613644 ( R-HSA-9619665 ) R-HSA-9613644 Reaction Name: SOX10-dependent POU3F1 gene expression See in Reactome R-HSA-9613648 ( R-HSA-9619665 ) R-HSA-9613648 Reaction Name: SOX10 dimer binds the POU3F1 promoter See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome
MONDO:0019587	ADGRV1	Q8WXG9	3.4.-.-	R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Developmental Biology	R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome
MONDO:0019588	ADGRV1	Q8WXG9	3.4.-.-	R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Developmental Biology	R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome
MONDO:0033668	SCD5	Q86SK9	1.14.19.1	R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism Developmental Biology	R-HSA-8847579 ( R-HSA-75105 ) R-HSA-8847579 Reaction Name: SCD5 desaturates ST-CoA to OLE-CoA See in Reactome R-HSA-9621399 ( R-HSA-9619665 ) R-HSA-9621399 Reaction Name: SCD5 gene expression See in Reactome
MONDO:0033853	CYP51A1	Q16850	1.14.14.154	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism Developmental Biology	R-HSA-1655847 ( R-HSA-2426168 ) R-HSA-1655847 Reaction Name: Expression of Lanosterol Demethylase (CYP51A1) See in Reactome R-HSA-194678 ( R-HSA-191273; R-HSA-211976 ) R-HSA-194678 Reaction Name: CYP51A1 demethylates LNSOL See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome