MONDO:0001567 |
MONDO:0001567
Disease Name: nephrocalcinosis
All associated enzymes in DAR:
AGXT
. The disease is also associated to other non-enzyme proteins (not in DAR).
AGXT |
P21549 |
2.6.1.44
2.6.1.51
|
R-HSA-389661
R-HSA-389661
Reactome Name: Glyoxylate metabolism and glycine degradation
See in Reactome
R-HSA-9033241
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-9609507
|
Metabolism
Protein localization
|
R-HSA-389684
(
R-HSA-389661
)
R-HSA-389684
Reaction Name: glyoxylate + alanine => glycine + pyruvate [peroxisome]
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0005090 |
DAO |
P14920 |
1.4.3.3
|
R-HSA-389661
R-HSA-389661
Reactome Name: Glyoxylate metabolism and glycine degradation
See in Reactome
R-HSA-9033241
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-9609507
|
Metabolism
Protein localization
|
R-HSA-389821
(
R-HSA-389661
)
R-HSA-389821
Reaction Name: glycine + O2 => glyoxylate + H2O2 + NH4+
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0005144 |
DAO |
P14920 |
1.4.3.3
|
R-HSA-389661
R-HSA-389661
Reactome Name: Glyoxylate metabolism and glycine degradation
See in Reactome
R-HSA-9033241
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-9609507
|
Metabolism
Protein localization
|
R-HSA-389821
(
R-HSA-389661
)
R-HSA-389821
Reaction Name: glycine + O2 => glyoxylate + H2O2 + NH4+
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0008145 |
IDH1 |
O75874 |
1.1.1.42
|
R-HSA-6798695
R-HSA-9033241
R-HSA-389542
|
R-HSA-168256
R-HSA-9609507
R-HSA-8978934
R-HSA-196854
R-HSA-196854
Reactome Name: Metabolism of vitamins and cofactors
See in Reactome
R-HSA-168249
R-HSA-1430728
|
Immune System
Protein localization
Metabolism
|
R-HSA-389540
(
R-HSA-389542
)
R-HSA-389540
Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+
See in Reactome
R-HSA-389550
(
R-HSA-389542
)
R-HSA-389550
Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+
See in Reactome
R-HSA-6798745
(
R-HSA-6798695
)
R-HSA-6798745
Reaction Name: Exocytosis of tertiary granule lumen proteins
See in Reactome
R-HSA-6798748
(
R-HSA-6798695
)
R-HSA-6798748
Reaction Name: Exocytosis of secretory granule lumen proteins
See in Reactome
R-HSA-6800434
(
R-HSA-6798695
)
R-HSA-6800434
Reaction Name: Exocytosis of ficolin-rich granule lumen proteins
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9761844
()
R-HSA-9761844
Reaction Name: NFE2L2-dependent IDH1 gene expression
See in Reactome
|
MONDO:0008171 |
MONDO:0008171
Disease Name: nephrolithiasis
OMIM id: OMIM:605990
All associated enzymes in DAR:
AGXT
. The disease is also associated to other non-enzyme proteins (not in DAR).
AGXT |
P21549 |
2.6.1.44
2.6.1.51
|
R-HSA-389661
R-HSA-389661
Reactome Name: Glyoxylate metabolism and glycine degradation
See in Reactome
R-HSA-9033241
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-9609507
|
Metabolism
Protein localization
|
R-HSA-389684
(
R-HSA-389661
)
R-HSA-389684
Reaction Name: glyoxylate + alanine => glycine + pyruvate [peroxisome]
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0008967 |
AMACR |
Q9UHK6 |
5.1.99.4
|
R-HSA-9033241
R-HSA-389887
R-HSA-389887
Reactome Name: Beta-oxidation of pristanoyl-CoA
See in Reactome
R-HSA-193368
R-HSA-193368
Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
See in Reactome
R-HSA-193775
R-HSA-193775
Reactome Name: Synthesis of bile acids and bile salts via 24-hydroxycholesterol
See in Reactome
|
R-HSA-194068
R-HSA-194068
Reactome Name: Bile acid and bile salt metabolism
See in Reactome
R-HSA-9609507
R-HSA-390918
R-HSA-1430728
R-HSA-8978868
R-HSA-192105
R-HSA-192105
Reactome Name: Synthesis of bile acids and bile salts
See in Reactome
R-HSA-556833
R-HSA-8957322
|
Protein localization
Metabolism
|
R-HSA-192056
(
R-HSA-193368
)
R-HSA-192056
Reaction Name: Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA
See in Reactome
R-HSA-193452
(
R-HSA-193368
)
R-HSA-193452
Reaction Name: Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA
See in Reactome
R-HSA-193736
(
R-HSA-193775
)
R-HSA-193736
Reaction Name: Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA
See in Reactome
R-HSA-193763
(
R-HSA-193775
)
R-HSA-193763
Reaction Name: Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA
See in Reactome
R-HSA-389897
(
R-HSA-389887
)
R-HSA-389897
Reaction Name: Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0009112 |
GNPAT |
O15228 |
2.3.1.42
|
R-HSA-9033241
R-HSA-75896
R-HSA-1483166
|
R-HSA-8848584
R-HSA-8848584
Reactome Name: Wax and plasmalogen biosynthesis
See in Reactome
R-HSA-9609507
R-HSA-1483257
R-HSA-1483206
R-HSA-1483206
Reactome Name: Glycerophospholipid biosynthesis
See in Reactome
R-HSA-1430728
R-HSA-556833
|
Protein localization
Metabolism
|
R-HSA-1483002
(
R-HSA-1483166
)
R-HSA-1483002
Reaction Name: DHAP is converted to 1-acyl GO3P by GNPAT
See in Reactome
R-HSA-390427
(
R-HSA-75896
)
R-HSA-390427
Reaction Name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate
See in Reactome
R-HSA-75879
(
R-HSA-75896
)
R-HSA-75879
Reaction Name: palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0009300 |
HSD17B4 |
P51659 |
1.1.1.n12
4.2.1.119
4.2.1.107
|
R-HSA-389887
R-HSA-389887
Reactome Name: Beta-oxidation of pristanoyl-CoA
See in Reactome
R-HSA-193368
R-HSA-193368
Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
See in Reactome
R-HSA-2046106
R-HSA-2046106
Reactome Name: alpha-linolenic acid (ALA) metabolism
See in Reactome
R-HSA-390247
R-HSA-390247
Reactome Name: Beta-oxidation of very long chain fatty acids
See in Reactome
R-HSA-9033500
R-HSA-9033500
Reactome Name: TYSND1 cleaves peroxisomal proteins
See in Reactome
R-HSA-9033241
|
R-HSA-194068
R-HSA-194068
Reactome Name: Bile acid and bile salt metabolism
See in Reactome
R-HSA-9609507
R-HSA-390918
R-HSA-2046104
R-HSA-2046104
Reactome Name: alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-192105
R-HSA-192105
Reactome Name: Synthesis of bile acids and bile salts
See in Reactome
R-HSA-556833
R-HSA-8957322
|
Protein localization
Metabolism
|
R-HSA-192331
(
R-HSA-193368
)
R-HSA-192331
Reaction Name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA
See in Reactome
R-HSA-193455
(
R-HSA-193368
)
R-HSA-193455
Reaction Name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA
See in Reactome
R-HSA-193508
(
R-HSA-193368
)
R-HSA-193508
Reaction Name: (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA
See in Reactome
R-HSA-193535
(
R-HSA-193368
)
R-HSA-193535
Reaction Name: 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA
See in Reactome
R-HSA-2066778
(
R-HSA-2046106
)
R-HSA-2066778
Reaction Name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA
See in Reactome
R-HSA-2066780
(
R-HSA-2046106
)
R-HSA-2066780
Reaction Name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA
See in Reactome
R-HSA-389986
(
R-HSA-389887
)
R-HSA-389986
Reaction Name: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA
See in Reactome
R-HSA-389995
(
R-HSA-389887
)
R-HSA-389995
Reaction Name: 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+
See in Reactome
R-HSA-390251
(
R-HSA-390247
)
R-HSA-390251
Reaction Name: HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA
See in Reactome
R-HSA-390252
(
R-HSA-390247
)
R-HSA-390252
Reaction Name: HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9033530
(
R-HSA-9033241;
R-HSA-9033500
)
|
MONDO:0009520 |
HMGCL |
P35914 |
4.1.3.4
|
R-HSA-9033241
R-HSA-77111
|
R-HSA-556833
R-HSA-74182
R-HSA-1430728
R-HSA-9609507
|
Metabolism
Protein localization
|
R-HSA-74180
(
R-HSA-77111
)
R-HSA-74180
Reaction Name: HMG CoA => acetoacetic acid + acetyl CoA
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0009556 |
MLYCD |
O95822 |
4.1.1.9
|
R-HSA-9033241
R-HSA-390247
R-HSA-390247
Reactome Name: Beta-oxidation of very long chain fatty acids
See in Reactome
|
R-HSA-556833
R-HSA-1430728
R-HSA-390918
R-HSA-9609507
R-HSA-8978868
|
Metabolism
Protein localization
|
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-977317
(
R-HSA-390247
)
R-HSA-977317
Reaction Name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome
See in Reactome
|
MONDO:0009823 |
AGXT |
P21549 |
2.6.1.44
2.6.1.51
|
R-HSA-389661
R-HSA-389661
Reactome Name: Glyoxylate metabolism and glycine degradation
See in Reactome
R-HSA-9033241
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-9609507
|
Metabolism
Protein localization
|
R-HSA-389684
(
R-HSA-389661
)
R-HSA-389684
Reaction Name: glyoxylate + alanine => glycine + pyruvate [peroxisome]
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0009855 |
HSD17B4 |
P51659 |
1.1.1.n12
4.2.1.119
4.2.1.107
|
R-HSA-389887
R-HSA-389887
Reactome Name: Beta-oxidation of pristanoyl-CoA
See in Reactome
R-HSA-193368
R-HSA-193368
Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
See in Reactome
R-HSA-2046106
R-HSA-2046106
Reactome Name: alpha-linolenic acid (ALA) metabolism
See in Reactome
R-HSA-390247
R-HSA-390247
Reactome Name: Beta-oxidation of very long chain fatty acids
See in Reactome
R-HSA-9033500
R-HSA-9033500
Reactome Name: TYSND1 cleaves peroxisomal proteins
See in Reactome
R-HSA-9033241
|
R-HSA-194068
R-HSA-194068
Reactome Name: Bile acid and bile salt metabolism
See in Reactome
R-HSA-9609507
R-HSA-390918
R-HSA-2046104
R-HSA-2046104
Reactome Name: alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-192105
R-HSA-192105
Reactome Name: Synthesis of bile acids and bile salts
See in Reactome
R-HSA-556833
R-HSA-8957322
|
Protein localization
Metabolism
|
R-HSA-192331
(
R-HSA-193368
)
R-HSA-192331
Reaction Name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA
See in Reactome
R-HSA-193455
(
R-HSA-193368
)
R-HSA-193455
Reaction Name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA
See in Reactome
R-HSA-193508
(
R-HSA-193368
)
R-HSA-193508
Reaction Name: (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA
See in Reactome
R-HSA-193535
(
R-HSA-193368
)
R-HSA-193535
Reaction Name: 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA
See in Reactome
R-HSA-2066778
(
R-HSA-2046106
)
R-HSA-2066778
Reaction Name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA
See in Reactome
R-HSA-2066780
(
R-HSA-2046106
)
R-HSA-2066780
Reaction Name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA
See in Reactome
R-HSA-389986
(
R-HSA-389887
)
R-HSA-389986
Reaction Name: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA
See in Reactome
R-HSA-389995
(
R-HSA-389887
)
R-HSA-389995
Reaction Name: 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+
See in Reactome
R-HSA-390251
(
R-HSA-390247
)
R-HSA-390251
Reaction Name: HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA
See in Reactome
R-HSA-390252
(
R-HSA-390247
)
R-HSA-390252
Reaction Name: HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9033530
(
R-HSA-9033241;
R-HSA-9033500
)
|
MONDO:0009855 |
EHHADH |
Q08426 |
5.3.3.8
1.1.1.35
4.2.1.17
|
R-HSA-9033241
R-HSA-390247
R-HSA-390247
Reactome Name: Beta-oxidation of very long chain fatty acids
See in Reactome
|
R-HSA-556833
R-HSA-1430728
R-HSA-390918
R-HSA-9609507
R-HSA-8978868
|
Metabolism
Protein localization
|
R-HSA-6809263
(
R-HSA-390247
)
R-HSA-6809263
Reaction Name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA
See in Reactome
R-HSA-6809264
(
R-HSA-390247
)
R-HSA-6809264
Reaction Name: EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0009919 |
ACOX1 |
Q15067 |
1.3.3.6
|
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9033500
R-HSA-9033500
Reactome Name: TYSND1 cleaves peroxisomal proteins
See in Reactome
R-HSA-9033241
R-HSA-2046106
R-HSA-2046106
Reactome Name: alpha-linolenic acid (ALA) metabolism
See in Reactome
R-HSA-390247
R-HSA-390247
Reactome Name: Beta-oxidation of very long chain fatty acids
See in Reactome
|
R-HSA-9609507
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-390918
R-HSA-2046104
R-HSA-2046104
Reactome Name: alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-556833
|
Protein localization
Metabolism
|
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9033515
(
R-HSA-9033241;
R-HSA-9033500
)
|
MONDO:0009958 |
PHYH |
O14832 |
1.14.11.18
|
R-HSA-9033500
R-HSA-9033500
Reactome Name: TYSND1 cleaves peroxisomal proteins
See in Reactome
R-HSA-9033241
R-HSA-389599
|
R-HSA-556833
R-HSA-1430728
R-HSA-390918
R-HSA-9609507
R-HSA-8978868
|
Metabolism
Protein localization
|
R-HSA-389639
(
R-HSA-389599
)
R-HSA-389639
Reaction Name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2
See in Reactome
R-HSA-9033232
(
R-HSA-9033241
)
R-HSA-9033232
Reaction Name: PEX7 binds cargo proteins containing PTS2
See in Reactome
R-HSA-9033238
(
R-HSA-9033241
)
R-HSA-9033238
Reaction Name: PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9033240
(
R-HSA-9033241
)
R-HSA-9033240
Reaction Name: PEX5L binds PEX7:Cargo protein
See in Reactome
R-HSA-9033490
(
R-HSA-9033241;
R-HSA-9033500
)
R-HSA-9033514
(
R-HSA-9033241
)
R-HSA-9033514
Reaction Name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix
See in Reactome
|
MONDO:0010487 |
USP9X |
Q93008 |
3.4.19.12
|
R-HSA-9033241
R-HSA-9013424
R-HSA-5689880
R-HSA-5689880
Reactome Name: Ub-specific processing proteases
See in Reactome
R-HSA-9013420
R-HSA-977225
R-HSA-8866652
R-HSA-8866652
Reactome Name: Synthesis of active ubiquitin: roles of E1 and E2 enzymes
See in Reactome
R-HSA-2173795
R-HSA-2173795
Reactome Name: Downregulation of SMAD2/3:SMAD4 transcriptional activity
See in Reactome
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9609507
R-HSA-9012999
R-HSA-212436
R-HSA-74160
R-HSA-170834
R-HSA-170834
Reactome Name: Signaling by TGF-beta Receptor Complex
See in Reactome
R-HSA-5688426
R-HSA-194315
R-HSA-392499
R-HSA-8852135
R-HSA-9006936
R-HSA-9006936
Reactome Name: Signaling by TGFB family members
See in Reactome
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-2173793
R-HSA-2173793
Reactome Name: Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
See in Reactome
R-HSA-162582
R-HSA-73857
|
Protein localization
Gene expression (Transcription)
Metabolism of proteins
Signal Transduction
|
R-HSA-5660752
(
R-HSA-977225
)
R-HSA-5661157
(
R-HSA-977225
)
R-HSA-5661161
(
R-HSA-977225
)
R-HSA-870437
(
R-HSA-2173795;
R-HSA-5689880
)
R-HSA-870437
Reaction Name: USP9X (FAM) deubiquitinates SMAD4
See in Reactome
R-HSA-870479
(
R-HSA-2173795;
R-HSA-5689880
)
R-HSA-870479
Reaction Name: USP9X (FAM) binds to ubiquitinated SMAD4
See in Reactome
R-HSA-8853503
(
R-HSA-8866652
)
R-HSA-8853503
Reaction Name: UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin
See in Reactome
R-HSA-8853514
(
R-HSA-8866652
)
R-HSA-8853514
Reaction Name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin
See in Reactome
R-HSA-9018766
(
R-HSA-9013420
)
R-HSA-9018766
Reaction Name: RHOU binds effectors at the plasma membrane
See in Reactome
R-HSA-9018794
(
R-HSA-9013424
)
R-HSA-9018794
Reaction Name: RHOV binds effectors at the plasma membrane
See in Reactome
R-HSA-9033478
(
R-HSA-9033241
)
R-HSA-9033478
Reaction Name: USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin
See in Reactome
R-HSA-9033491
(
R-HSA-9033241
)
R-HSA-9033491
Reaction Name: USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin
See in Reactome
R-HSA-9033509
(
R-HSA-9033241
)
R-HSA-9033526
(
R-HSA-9033241
)
|
MONDO:0010502 |
USP9X |
Q93008 |
3.4.19.12
|
R-HSA-9033241
R-HSA-9013424
R-HSA-5689880
R-HSA-5689880
Reactome Name: Ub-specific processing proteases
See in Reactome
R-HSA-9013420
R-HSA-977225
R-HSA-8866652
R-HSA-8866652
Reactome Name: Synthesis of active ubiquitin: roles of E1 and E2 enzymes
See in Reactome
R-HSA-2173795
R-HSA-2173795
Reactome Name: Downregulation of SMAD2/3:SMAD4 transcriptional activity
See in Reactome
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9609507
R-HSA-9012999
R-HSA-212436
R-HSA-74160
R-HSA-170834
R-HSA-170834
Reactome Name: Signaling by TGF-beta Receptor Complex
See in Reactome
R-HSA-5688426
R-HSA-194315
R-HSA-392499
R-HSA-8852135
R-HSA-9006936
R-HSA-9006936
Reactome Name: Signaling by TGFB family members
See in Reactome
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-2173793
R-HSA-2173793
Reactome Name: Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
See in Reactome
R-HSA-162582
R-HSA-73857
|
Protein localization
Gene expression (Transcription)
Metabolism of proteins
Signal Transduction
|
R-HSA-5660752
(
R-HSA-977225
)
R-HSA-5661157
(
R-HSA-977225
)
R-HSA-5661161
(
R-HSA-977225
)
R-HSA-870437
(
R-HSA-2173795;
R-HSA-5689880
)
R-HSA-870437
Reaction Name: USP9X (FAM) deubiquitinates SMAD4
See in Reactome
R-HSA-870479
(
R-HSA-2173795;
R-HSA-5689880
)
R-HSA-870479
Reaction Name: USP9X (FAM) binds to ubiquitinated SMAD4
See in Reactome
R-HSA-8853503
(
R-HSA-8866652
)
R-HSA-8853503
Reaction Name: UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin
See in Reactome
R-HSA-8853514
(
R-HSA-8866652
)
R-HSA-8853514
Reaction Name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin
See in Reactome
R-HSA-9018766
(
R-HSA-9013420
)
R-HSA-9018766
Reaction Name: RHOU binds effectors at the plasma membrane
See in Reactome
R-HSA-9018794
(
R-HSA-9013424
)
R-HSA-9018794
Reaction Name: RHOV binds effectors at the plasma membrane
See in Reactome
R-HSA-9033478
(
R-HSA-9033241
)
R-HSA-9033478
Reaction Name: USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin
See in Reactome
R-HSA-9033491
(
R-HSA-9033241
)
R-HSA-9033491
Reaction Name: USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin
See in Reactome
R-HSA-9033509
(
R-HSA-9033241
)
R-HSA-9033526
(
R-HSA-9033241
)
|
MONDO:0010823 |
AGPS |
O00116 |
2.5.1.26
|
R-HSA-9033500
R-HSA-9033500
Reactome Name: TYSND1 cleaves peroxisomal proteins
See in Reactome
R-HSA-9033241
R-HSA-75896
|
R-HSA-556833
R-HSA-8848584
R-HSA-8848584
Reactome Name: Wax and plasmalogen biosynthesis
See in Reactome
R-HSA-1430728
R-HSA-9609507
|
Metabolism
Protein localization
|
R-HSA-390427
(
R-HSA-75896
)
R-HSA-390427
Reaction Name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate
See in Reactome
R-HSA-75879
(
R-HSA-75896
)
R-HSA-75879
Reaction Name: palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH
See in Reactome
R-HSA-9033232
(
R-HSA-9033241
)
R-HSA-9033232
Reaction Name: PEX7 binds cargo proteins containing PTS2
See in Reactome
R-HSA-9033238
(
R-HSA-9033241
)
R-HSA-9033238
Reaction Name: PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9033240
(
R-HSA-9033241
)
R-HSA-9033240
Reaction Name: PEX5L binds PEX7:Cargo protein
See in Reactome
R-HSA-9033506
(
R-HSA-9033241;
R-HSA-9033500
)
R-HSA-9033514
(
R-HSA-9033241
)
R-HSA-9033514
Reaction Name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix
See in Reactome
|
MONDO:0011905 |
MONDO:0011905
Disease Name: obsolete familial hypercholanemia
All associated enzymes in DAR:
BAAT
. The disease is also associated to other non-enzyme proteins (not in DAR).
BAAT |
Q14032 |
3.1.2.27
2.3.1.65
3.1.2.2
|
R-HSA-193368
R-HSA-193368
Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
See in Reactome
R-HSA-9033241
R-HSA-159418
R-HSA-159418
Reactome Name: Recycling of bile acids and salts
See in Reactome
|
R-HSA-194068
R-HSA-194068
Reactome Name: Bile acid and bile salt metabolism
See in Reactome
R-HSA-9609507
R-HSA-1430728
R-HSA-192105
R-HSA-192105
Reactome Name: Synthesis of bile acids and bile salts
See in Reactome
R-HSA-556833
R-HSA-8957322
|
Protein localization
Metabolism
|
R-HSA-159431
(
R-HSA-159418
)
R-HSA-159431
Reaction Name: Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine
See in Reactome
R-HSA-192312
(
R-HSA-193368
)
R-HSA-192312
Reaction Name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate
See in Reactome
R-HSA-193491
(
R-HSA-193368
)
R-HSA-193491
Reaction Name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0013391 |
SCP2 |
P22307 |
2.3.1.176
2.3.1.16
2.3.1.155
|
R-HSA-2046106
R-HSA-2046106
Reactome Name: alpha-linolenic acid (ALA) metabolism
See in Reactome
R-HSA-389887
R-HSA-389887
Reactome Name: Beta-oxidation of pristanoyl-CoA
See in Reactome
R-HSA-193368
R-HSA-193368
Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
See in Reactome
R-HSA-9033241
R-HSA-9033500
R-HSA-9033500
Reactome Name: TYSND1 cleaves peroxisomal proteins
See in Reactome
|
R-HSA-194068
R-HSA-194068
Reactome Name: Bile acid and bile salt metabolism
See in Reactome
R-HSA-9609507
R-HSA-390918
R-HSA-2046104
R-HSA-2046104
Reactome Name: alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-192105
R-HSA-192105
Reactome Name: Synthesis of bile acids and bile salts
See in Reactome
R-HSA-556833
R-HSA-8957322
|
Protein localization
Metabolism
|
R-HSA-2066781
(
R-HSA-2046106
)
R-HSA-2066781
Reaction Name: Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx)
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9033524
(
R-HSA-9033241;
R-HSA-9033500
)
|
MONDO:0013571 |
CAT |
P04040 |
1.11.1.6
|
R-HSA-6798695
R-HSA-9615017
R-HSA-9615017
Reactome Name: FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
See in Reactome
R-HSA-3299685
R-HSA-3299685
Reactome Name: Detoxification of Reactive Oxygen Species
See in Reactome
R-HSA-9033241
|
R-HSA-8953897
R-HSA-9609507
R-HSA-9614085
R-HSA-168256
R-HSA-168249
R-HSA-2262752
R-HSA-212436
R-HSA-9711123
R-HSA-9711123
Reactome Name: Cellular response to chemical stress
See in Reactome
R-HSA-74160
R-HSA-73857
|
Cellular responses to stimuli
Protein localization
Immune System
Gene expression (Transcription)
|
R-HSA-6798748
(
R-HSA-6798695
)
R-HSA-6798748
Reaction Name: Exocytosis of secretory granule lumen proteins
See in Reactome
R-HSA-6800434
(
R-HSA-6798695
)
R-HSA-6800434
Reaction Name: Exocytosis of ficolin-rich granule lumen proteins
See in Reactome
R-HSA-76031
(
R-HSA-3299685
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9622738
(
R-HSA-9615017
)
R-HSA-9622738
Reaction Name: CAT gene expression is stimulated by FOXO3,FOXO6,(FOXO1)
See in Reactome
|
MONDO:0013808 |
IDH1 |
O75874 |
1.1.1.42
|
R-HSA-6798695
R-HSA-9033241
R-HSA-389542
|
R-HSA-168256
R-HSA-9609507
R-HSA-8978934
R-HSA-196854
R-HSA-196854
Reactome Name: Metabolism of vitamins and cofactors
See in Reactome
R-HSA-168249
R-HSA-1430728
|
Immune System
Protein localization
Metabolism
|
R-HSA-389540
(
R-HSA-389542
)
R-HSA-389540
Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+
See in Reactome
R-HSA-389550
(
R-HSA-389542
)
R-HSA-389550
Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+
See in Reactome
R-HSA-6798745
(
R-HSA-6798695
)
R-HSA-6798745
Reaction Name: Exocytosis of tertiary granule lumen proteins
See in Reactome
R-HSA-6798748
(
R-HSA-6798695
)
R-HSA-6798748
Reaction Name: Exocytosis of secretory granule lumen proteins
See in Reactome
R-HSA-6800434
(
R-HSA-6798695
)
R-HSA-6800434
Reaction Name: Exocytosis of ficolin-rich granule lumen proteins
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9761844
()
R-HSA-9761844
Reaction Name: NFE2L2-dependent IDH1 gene expression
See in Reactome
|
MONDO:0013941 |
IDH1 |
O75874 |
1.1.1.42
|
R-HSA-6798695
R-HSA-9033241
R-HSA-389542
|
R-HSA-168256
R-HSA-9609507
R-HSA-8978934
R-HSA-196854
R-HSA-196854
Reactome Name: Metabolism of vitamins and cofactors
See in Reactome
R-HSA-168249
R-HSA-1430728
|
Immune System
Protein localization
Metabolism
|
R-HSA-389540
(
R-HSA-389542
)
R-HSA-389540
Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+
See in Reactome
R-HSA-389550
(
R-HSA-389542
)
R-HSA-389550
Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+
See in Reactome
R-HSA-6798745
(
R-HSA-6798695
)
R-HSA-6798745
Reaction Name: Exocytosis of tertiary granule lumen proteins
See in Reactome
R-HSA-6798748
(
R-HSA-6798695
)
R-HSA-6798748
Reaction Name: Exocytosis of secretory granule lumen proteins
See in Reactome
R-HSA-6800434
(
R-HSA-6798695
)
R-HSA-6800434
Reaction Name: Exocytosis of ficolin-rich granule lumen proteins
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9761844
()
R-HSA-9761844
Reaction Name: NFE2L2-dependent IDH1 gene expression
See in Reactome
|
MONDO:0014275 |
EHHADH |
Q08426 |
5.3.3.8
1.1.1.35
4.2.1.17
|
R-HSA-9033241
R-HSA-390247
R-HSA-390247
Reactome Name: Beta-oxidation of very long chain fatty acids
See in Reactome
|
R-HSA-556833
R-HSA-1430728
R-HSA-390918
R-HSA-9609507
R-HSA-8978868
|
Metabolism
Protein localization
|
R-HSA-6809263
(
R-HSA-390247
)
R-HSA-6809263
Reaction Name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA
See in Reactome
R-HSA-6809264
(
R-HSA-390247
)
R-HSA-6809264
Reaction Name: EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0015015 |
ACOX2 |
Q99424 |
1.17.99.3
|
R-HSA-9033241
R-HSA-389887
R-HSA-389887
Reactome Name: Beta-oxidation of pristanoyl-CoA
See in Reactome
R-HSA-193368
R-HSA-193368
Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
See in Reactome
|
R-HSA-194068
R-HSA-194068
Reactome Name: Bile acid and bile salt metabolism
See in Reactome
R-HSA-9609507
R-HSA-390918
R-HSA-1430728
R-HSA-8978868
R-HSA-192105
R-HSA-192105
Reactome Name: Synthesis of bile acids and bile salts
See in Reactome
R-HSA-556833
R-HSA-8957322
|
Protein localization
Metabolism
|
R-HSA-192335
(
R-HSA-193368
)
R-HSA-192335
Reaction Name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA)
See in Reactome
R-HSA-193369
(
R-HSA-193368
)
R-HSA-193369
Reaction Name: 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA
See in Reactome
R-HSA-389889
(
R-HSA-389887
)
R-HSA-389889
Reaction Name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0016244 |
BAAT |
Q14032 |
3.1.2.27
2.3.1.65
3.1.2.2
|
R-HSA-193368
R-HSA-193368
Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
See in Reactome
R-HSA-9033241
R-HSA-159418
R-HSA-159418
Reactome Name: Recycling of bile acids and salts
See in Reactome
|
R-HSA-194068
R-HSA-194068
Reactome Name: Bile acid and bile salt metabolism
See in Reactome
R-HSA-9609507
R-HSA-1430728
R-HSA-192105
R-HSA-192105
Reactome Name: Synthesis of bile acids and bile salts
See in Reactome
R-HSA-556833
R-HSA-8957322
|
Protein localization
Metabolism
|
R-HSA-159431
(
R-HSA-159418
)
R-HSA-159431
Reaction Name: Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine
See in Reactome
R-HSA-192312
(
R-HSA-193368
)
R-HSA-192312
Reaction Name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate
See in Reactome
R-HSA-193491
(
R-HSA-193368
)
R-HSA-193491
Reaction Name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0018821 |
USP9X |
Q93008 |
3.4.19.12
|
R-HSA-9033241
R-HSA-9013424
R-HSA-5689880
R-HSA-5689880
Reactome Name: Ub-specific processing proteases
See in Reactome
R-HSA-9013420
R-HSA-977225
R-HSA-8866652
R-HSA-8866652
Reactome Name: Synthesis of active ubiquitin: roles of E1 and E2 enzymes
See in Reactome
R-HSA-2173795
R-HSA-2173795
Reactome Name: Downregulation of SMAD2/3:SMAD4 transcriptional activity
See in Reactome
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9609507
R-HSA-9012999
R-HSA-212436
R-HSA-74160
R-HSA-170834
R-HSA-170834
Reactome Name: Signaling by TGF-beta Receptor Complex
See in Reactome
R-HSA-5688426
R-HSA-194315
R-HSA-392499
R-HSA-8852135
R-HSA-9006936
R-HSA-9006936
Reactome Name: Signaling by TGFB family members
See in Reactome
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-2173793
R-HSA-2173793
Reactome Name: Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
See in Reactome
R-HSA-162582
R-HSA-73857
|
Protein localization
Gene expression (Transcription)
Metabolism of proteins
Signal Transduction
|
R-HSA-5660752
(
R-HSA-977225
)
R-HSA-5661157
(
R-HSA-977225
)
R-HSA-5661161
(
R-HSA-977225
)
R-HSA-870437
(
R-HSA-2173795;
R-HSA-5689880
)
R-HSA-870437
Reaction Name: USP9X (FAM) deubiquitinates SMAD4
See in Reactome
R-HSA-870479
(
R-HSA-2173795;
R-HSA-5689880
)
R-HSA-870479
Reaction Name: USP9X (FAM) binds to ubiquitinated SMAD4
See in Reactome
R-HSA-8853503
(
R-HSA-8866652
)
R-HSA-8853503
Reaction Name: UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin
See in Reactome
R-HSA-8853514
(
R-HSA-8866652
)
R-HSA-8853514
Reaction Name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin
See in Reactome
R-HSA-9018766
(
R-HSA-9013420
)
R-HSA-9018766
Reaction Name: RHOU binds effectors at the plasma membrane
See in Reactome
R-HSA-9018794
(
R-HSA-9013424
)
R-HSA-9018794
Reaction Name: RHOV binds effectors at the plasma membrane
See in Reactome
R-HSA-9033478
(
R-HSA-9033241
)
R-HSA-9033478
Reaction Name: USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin
See in Reactome
R-HSA-9033491
(
R-HSA-9033241
)
R-HSA-9033491
Reaction Name: USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin
See in Reactome
R-HSA-9033509
(
R-HSA-9033241
)
R-HSA-9033526
(
R-HSA-9033241
)
|
MONDO:0019200 |
PHYH |
O14832 |
1.14.11.18
|
R-HSA-9033500
R-HSA-9033500
Reactome Name: TYSND1 cleaves peroxisomal proteins
See in Reactome
R-HSA-9033241
R-HSA-389599
|
R-HSA-556833
R-HSA-1430728
R-HSA-390918
R-HSA-9609507
R-HSA-8978868
|
Metabolism
Protein localization
|
R-HSA-389639
(
R-HSA-389599
)
R-HSA-389639
Reaction Name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2
See in Reactome
R-HSA-9033232
(
R-HSA-9033241
)
R-HSA-9033232
Reaction Name: PEX7 binds cargo proteins containing PTS2
See in Reactome
R-HSA-9033238
(
R-HSA-9033241
)
R-HSA-9033238
Reaction Name: PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9033240
(
R-HSA-9033241
)
R-HSA-9033240
Reaction Name: PEX5L binds PEX7:Cargo protein
See in Reactome
R-HSA-9033490
(
R-HSA-9033241;
R-HSA-9033500
)
R-HSA-9033514
(
R-HSA-9033241
)
R-HSA-9033514
Reaction Name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix
See in Reactome
|
MONDO:0019536 |
BAAT |
Q14032 |
3.1.2.27
2.3.1.65
3.1.2.2
|
R-HSA-193368
R-HSA-193368
Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
See in Reactome
R-HSA-9033241
R-HSA-159418
R-HSA-159418
Reactome Name: Recycling of bile acids and salts
See in Reactome
|
R-HSA-194068
R-HSA-194068
Reactome Name: Bile acid and bile salt metabolism
See in Reactome
R-HSA-9609507
R-HSA-1430728
R-HSA-192105
R-HSA-192105
Reactome Name: Synthesis of bile acids and bile salts
See in Reactome
R-HSA-556833
R-HSA-8957322
|
Protein localization
Metabolism
|
R-HSA-159431
(
R-HSA-159418
)
R-HSA-159431
Reaction Name: Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine
See in Reactome
R-HSA-192312
(
R-HSA-193368
)
R-HSA-192312
Reaction Name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate
See in Reactome
R-HSA-193491
(
R-HSA-193368
)
R-HSA-193491
Reaction Name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0024498 |
IDH1 |
O75874 |
1.1.1.42
|
R-HSA-6798695
R-HSA-9033241
R-HSA-389542
|
R-HSA-168256
R-HSA-9609507
R-HSA-8978934
R-HSA-196854
R-HSA-196854
Reactome Name: Metabolism of vitamins and cofactors
See in Reactome
R-HSA-168249
R-HSA-1430728
|
Immune System
Protein localization
Metabolism
|
R-HSA-389540
(
R-HSA-389542
)
R-HSA-389540
Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+
See in Reactome
R-HSA-389550
(
R-HSA-389542
)
R-HSA-389550
Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+
See in Reactome
R-HSA-6798745
(
R-HSA-6798695
)
R-HSA-6798745
Reaction Name: Exocytosis of tertiary granule lumen proteins
See in Reactome
R-HSA-6798748
(
R-HSA-6798695
)
R-HSA-6798748
Reaction Name: Exocytosis of secretory granule lumen proteins
See in Reactome
R-HSA-6800434
(
R-HSA-6798695
)
R-HSA-6800434
Reaction Name: Exocytosis of ficolin-rich granule lumen proteins
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9761844
()
R-HSA-9761844
Reaction Name: NFE2L2-dependent IDH1 gene expression
See in Reactome
|
MONDO:0030073 |
ACOX1 |
Q15067 |
1.3.3.6
|
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9033500
R-HSA-9033500
Reactome Name: TYSND1 cleaves peroxisomal proteins
See in Reactome
R-HSA-9033241
R-HSA-2046106
R-HSA-2046106
Reactome Name: alpha-linolenic acid (ALA) metabolism
See in Reactome
R-HSA-390247
R-HSA-390247
Reactome Name: Beta-oxidation of very long chain fatty acids
See in Reactome
|
R-HSA-9609507
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-390918
R-HSA-2046104
R-HSA-2046104
Reactome Name: alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-556833
|
Protein localization
Metabolism
|
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
R-HSA-9033515
(
R-HSA-9033241;
R-HSA-9033500
)
|
MONDO:0030991 |
BAAT |
Q14032 |
3.1.2.27
2.3.1.65
3.1.2.2
|
R-HSA-193368
R-HSA-193368
Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
See in Reactome
R-HSA-9033241
R-HSA-159418
R-HSA-159418
Reactome Name: Recycling of bile acids and salts
See in Reactome
|
R-HSA-194068
R-HSA-194068
Reactome Name: Bile acid and bile salt metabolism
See in Reactome
R-HSA-9609507
R-HSA-1430728
R-HSA-192105
R-HSA-192105
Reactome Name: Synthesis of bile acids and bile salts
See in Reactome
R-HSA-556833
R-HSA-8957322
|
Protein localization
Metabolism
|
R-HSA-159431
(
R-HSA-159418
)
R-HSA-159431
Reaction Name: Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine
See in Reactome
R-HSA-192312
(
R-HSA-193368
)
R-HSA-192312
Reaction Name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate
See in Reactome
R-HSA-193491
(
R-HSA-193368
)
R-HSA-193491
Reaction Name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0031446 |
BAAT |
Q14032 |
3.1.2.27
2.3.1.65
3.1.2.2
|
R-HSA-193368
R-HSA-193368
Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
See in Reactome
R-HSA-9033241
R-HSA-159418
R-HSA-159418
Reactome Name: Recycling of bile acids and salts
See in Reactome
|
R-HSA-194068
R-HSA-194068
Reactome Name: Bile acid and bile salt metabolism
See in Reactome
R-HSA-9609507
R-HSA-1430728
R-HSA-192105
R-HSA-192105
Reactome Name: Synthesis of bile acids and bile salts
See in Reactome
R-HSA-556833
R-HSA-8957322
|
Protein localization
Metabolism
|
R-HSA-159431
(
R-HSA-159418
)
R-HSA-159431
Reaction Name: Cytosolic chenodeoxycholoyl-CoA or choloyl-CoA are conjugated with glycine or taurine
See in Reactome
R-HSA-192312
(
R-HSA-193368
)
R-HSA-192312
Reaction Name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate
See in Reactome
R-HSA-193491
(
R-HSA-193368
)
R-HSA-193491
Reaction Name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|
MONDO:0054764 |
CRAT |
P43155 |
2.3.1.137
2.3.1.7
|
R-HSA-9033241
R-HSA-389887
R-HSA-389887
Reactome Name: Beta-oxidation of pristanoyl-CoA
See in Reactome
|
R-HSA-556833
R-HSA-1430728
R-HSA-390918
R-HSA-9609507
R-HSA-8978868
|
Metabolism
Protein localization
|
R-HSA-390284
(
R-HSA-389887
)
R-HSA-390284
Reaction Name: propionyl-CoA + carnitine => propionylcarnitine + CoASH
See in Reactome
R-HSA-390291
(
R-HSA-389887
)
R-HSA-390291
Reaction Name: acetyl-CoA + carnitine => acetylcarnitine + CoASH
See in Reactome
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
(
R-HSA-9033241
)
R-HSA-9033233
Reaction Name: PEX5S,L binds cargo proteins containing PTS1
See in Reactome
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
(
R-HSA-9033241
)
R-HSA-9033235
Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix
See in Reactome
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
(
R-HSA-9033241
)
R-HSA-9033236
Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
See in Reactome
|