MONDO:0008214 |
LBR |
Q14739 |
1.3.1.70
|
R-HSA-191273
R-HSA-9013106
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-8980692
R-HSA-9013408
R-HSA-9013423
R-HSA-9013404
R-HSA-9013405
R-HSA-9013149
R-HSA-9013148
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9012999
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-212436
R-HSA-74160
R-HSA-194315
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-556833
R-HSA-69278
R-HSA-1430728
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-1640170
R-HSA-8957322
R-HSA-162582
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Cell Cycle
Signal Transduction
|
R-HSA-194674
(
R-HSA-191273
)
R-HSA-194674
Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]
See in Reactome
R-HSA-9013004
(
R-HSA-8980692
)
R-HSA-9013004
Reaction Name: RHOA binds effectors at the ER membrane
See in Reactome
R-HSA-9013438
(
R-HSA-9013405
)
R-HSA-9013438
Reaction Name: RHOD binds effectors at the endosome membrane
See in Reactome
R-HSA-9014467
(
R-HSA-9013408
)
R-HSA-9014467
Reaction Name: RHOG binds effectors at the ER membrane
See in Reactome
R-HSA-9018594
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9624798
(
R-HSA-2995383
)
R-HSA-9624800
(
R-HSA-2995383
)
R-HSA-9691174
(
R-HSA-9013149
)
R-HSA-9691174
Reaction Name: RAC1 binds effectors at the ER membrane
See in Reactome
R-HSA-9692809
(
R-HSA-9013148
)
R-HSA-9692809
Reaction Name: CDC42 binds effectors at the ER membrane
See in Reactome
R-HSA-9714361
(
R-HSA-9013106
)
R-HSA-9714361
Reaction Name: RHOC activates endoplasmic reticulum effectors
See in Reactome
R-HSA-9714481
(
R-HSA-9013404
)
R-HSA-9714481
Reaction Name: RAC2 binds effectors at the ER membrane
See in Reactome
R-HSA-9714691
(
R-HSA-9013423
)
|
MONDO:0008974 |
LBR |
Q14739 |
1.3.1.70
|
R-HSA-191273
R-HSA-9013106
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-8980692
R-HSA-9013408
R-HSA-9013423
R-HSA-9013404
R-HSA-9013405
R-HSA-9013149
R-HSA-9013148
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9012999
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-212436
R-HSA-74160
R-HSA-194315
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-556833
R-HSA-69278
R-HSA-1430728
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-1640170
R-HSA-8957322
R-HSA-162582
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Cell Cycle
Signal Transduction
|
R-HSA-194674
(
R-HSA-191273
)
R-HSA-194674
Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]
See in Reactome
R-HSA-9013004
(
R-HSA-8980692
)
R-HSA-9013004
Reaction Name: RHOA binds effectors at the ER membrane
See in Reactome
R-HSA-9013438
(
R-HSA-9013405
)
R-HSA-9013438
Reaction Name: RHOD binds effectors at the endosome membrane
See in Reactome
R-HSA-9014467
(
R-HSA-9013408
)
R-HSA-9014467
Reaction Name: RHOG binds effectors at the ER membrane
See in Reactome
R-HSA-9018594
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9624798
(
R-HSA-2995383
)
R-HSA-9624800
(
R-HSA-2995383
)
R-HSA-9691174
(
R-HSA-9013149
)
R-HSA-9691174
Reaction Name: RAC1 binds effectors at the ER membrane
See in Reactome
R-HSA-9692809
(
R-HSA-9013148
)
R-HSA-9692809
Reaction Name: CDC42 binds effectors at the ER membrane
See in Reactome
R-HSA-9714361
(
R-HSA-9013106
)
R-HSA-9714361
Reaction Name: RHOC activates endoplasmic reticulum effectors
See in Reactome
R-HSA-9714481
(
R-HSA-9013404
)
R-HSA-9714481
Reaction Name: RAC2 binds effectors at the ER membrane
See in Reactome
R-HSA-9714691
(
R-HSA-9013423
)
|
MONDO:0013276 |
LBR |
Q14739 |
1.3.1.70
|
R-HSA-191273
R-HSA-9013106
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-8980692
R-HSA-9013408
R-HSA-9013423
R-HSA-9013404
R-HSA-9013405
R-HSA-9013149
R-HSA-9013148
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9012999
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-212436
R-HSA-74160
R-HSA-194315
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-556833
R-HSA-69278
R-HSA-1430728
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-1640170
R-HSA-8957322
R-HSA-162582
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Cell Cycle
Signal Transduction
|
R-HSA-194674
(
R-HSA-191273
)
R-HSA-194674
Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]
See in Reactome
R-HSA-9013004
(
R-HSA-8980692
)
R-HSA-9013004
Reaction Name: RHOA binds effectors at the ER membrane
See in Reactome
R-HSA-9013438
(
R-HSA-9013405
)
R-HSA-9013438
Reaction Name: RHOD binds effectors at the endosome membrane
See in Reactome
R-HSA-9014467
(
R-HSA-9013408
)
R-HSA-9014467
Reaction Name: RHOG binds effectors at the ER membrane
See in Reactome
R-HSA-9018594
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9624798
(
R-HSA-2995383
)
R-HSA-9624800
(
R-HSA-2995383
)
R-HSA-9691174
(
R-HSA-9013149
)
R-HSA-9691174
Reaction Name: RAC1 binds effectors at the ER membrane
See in Reactome
R-HSA-9692809
(
R-HSA-9013148
)
R-HSA-9692809
Reaction Name: CDC42 binds effectors at the ER membrane
See in Reactome
R-HSA-9714361
(
R-HSA-9013106
)
R-HSA-9714361
Reaction Name: RHOC activates endoplasmic reticulum effectors
See in Reactome
R-HSA-9714481
(
R-HSA-9013404
)
R-HSA-9714481
Reaction Name: RAC2 binds effectors at the ER membrane
See in Reactome
R-HSA-9714691
(
R-HSA-9013423
)
|
MONDO:0014359 |
PRKACA |
P17612 |
2.7.11.11
|
R-HSA-442720
R-HSA-442720
Reactome Name: CREB1 phosphorylation through the activation of Adenylate Cyclase
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-381676
R-HSA-381676
Reactome Name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
See in Reactome
R-HSA-380259
R-HSA-380259
Reactome Name: Loss of Nlp from mitotic centrosomes
See in Reactome
R-HSA-983231
R-HSA-983231
Reactome Name: Factors involved in megakaryocyte development and platelet production
See in Reactome
R-HSA-432040
R-HSA-432040
Reactome Name: Vasopressin regulates renal water homeostasis via Aquaporins
See in Reactome
R-HSA-380270
R-HSA-380270
Reactome Name: Recruitment of mitotic centrosome proteins and complexes
See in Reactome
R-HSA-5610783
R-HSA-5610783
Reactome Name: Degradation of GLI2 by the proteasome
See in Reactome
R-HSA-111931
R-HSA-111931
Reactome Name: PKA-mediated phosphorylation of CREB
See in Reactome
R-HSA-180024
R-HSA-5610787
R-HSA-163615
R-HSA-5610785
R-HSA-5610785
Reactome Name: GLI3 is processed to GLI3R by the proteasome
See in Reactome
R-HSA-164378
R-HSA-164378
Reactome Name: PKA activation in glucagon signalling
See in Reactome
R-HSA-5578775
R-HSA-8853659
R-HSA-9010642
R-HSA-8854518
R-HSA-4420097
R-HSA-380284
R-HSA-380284
Reactome Name: Loss of proteins required for interphase microtubule organization from the centrosome
See in Reactome
R-HSA-5687128
R-HSA-163560
R-HSA-5610780
R-HSA-5610780
Reactome Name: Degradation of GLI1 by the proteasome
See in Reactome
R-HSA-5620912
R-HSA-5620912
Reactome Name: Anchoring of the basal body to the plasma membrane
See in Reactome
R-HSA-512988
R-HSA-512988
Reactome Name: Interleukin-3, Interleukin-5 and GM-CSF signaling
See in Reactome
R-HSA-8963896
R-HSA-392517
R-HSA-163358
R-HSA-163358
Reactome Name: PKA-mediated phosphorylation of key metabolic factors
See in Reactome
R-HSA-422356
R-HSA-422356
Reactome Name: Regulation of insulin secretion
See in Reactome
R-HSA-2565942
R-HSA-2565942
Reactome Name: Regulation of PLK1 Activity at G2/M Transition
See in Reactome
R-HSA-380320
R-HSA-380320
Reactome Name: Recruitment of NuMA to mitotic centrosomes
See in Reactome
R-HSA-5621575
R-HSA-9634600
R-HSA-9634600
Reactome Name: Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
See in Reactome
|
R-HSA-376176
R-HSA-70326
R-HSA-111997
R-HSA-111996
R-HSA-397014
R-HSA-418594
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-168256
R-HSA-382551
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-9006925
R-HSA-9006925
Reactome Name: Intracellular signaling by second messengers
See in Reactome
R-HSA-1430728
R-HSA-5358351
R-HSA-1640170
R-HSA-5617833
R-HSA-1280218
R-HSA-1266738
R-HSA-1489509
R-HSA-111933
R-HSA-71387
R-HSA-163359
R-HSA-163359
Reactome Name: Glucagon signaling in metabolic regulation
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-1852241
R-HSA-1852241
Reactome Name: Organelle biogenesis and maintenance
See in Reactome
R-HSA-449147
R-HSA-9675108
R-HSA-69278
R-HSA-8979227
R-HSA-112316
R-HSA-372790
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-69275
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-5576891
R-HSA-556833
R-HSA-174824
R-HSA-174824
Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance
See in Reactome
R-HSA-388396
R-HSA-380287
R-HSA-168249
R-HSA-163685
R-HSA-163685
Reactome Name: Integration of energy metabolism
See in Reactome
R-HSA-445717
R-HSA-453274
R-HSA-68886
R-HSA-70171
R-HSA-8963898
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-112043
R-HSA-112040
R-HSA-73857
R-HSA-111885
R-HSA-109582
R-HSA-194138
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-68877
R-HSA-162582
|
Muscle contraction
Immune System
Transport of small molecules
Metabolism
Cell Cycle
Developmental Biology
Gene expression (Transcription)
Organelle biogenesis and maintenance
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-111919
(
R-HSA-111931;
R-HSA-442720
)
R-HSA-111924
(
R-HSA-111931;
R-HSA-442720
)
R-HSA-111924
Reaction Name: PKA catalytic subunit translocates to the nucleus
See in Reactome
R-HSA-111925
(
R-HSA-111931;
R-HSA-163615;
R-HSA-164378;
R-HSA-180024;
R-HSA-432040;
R-HSA-442720
)
R-HSA-111925
Reaction Name: cAMP induces dissociation of inactive PKA tetramers
See in Reactome
R-HSA-163416
(
R-HSA-163560
)
R-HSA-163416
Reaction Name: hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP
See in Reactome
R-HSA-163418
(
R-HSA-163560
)
R-HSA-163418
Reaction Name: perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP
See in Reactome
R-HSA-163672
(
R-HSA-163358
)
R-HSA-163672
Reaction Name: Phosphorylation of ChREBP at Thr(666) by PKA
See in Reactome
R-HSA-163676
(
R-HSA-163358
)
R-HSA-163676
Reaction Name: Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA
See in Reactome
R-HSA-163773
(
R-HSA-163358;
R-HSA-9634600
)
R-HSA-163773
Reaction Name: Phosphorylation of PF2K-Pase by PKA catalytic subunit
See in Reactome
R-HSA-177275
(
R-HSA-180024
)
R-HSA-177275
Reaction Name: PKA phosphorylates DARPP-32 on Thr34
See in Reactome
R-HSA-177284
(
R-HSA-180024
)
R-HSA-180073
(
R-HSA-180024
)
R-HSA-180073
Reaction Name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function
See in Reactome
R-HSA-2574840
(
R-HSA-2565942
)
R-HSA-2574840
Reaction Name: AJUBA facilitates AURKA autophosphorylation
See in Reactome
R-HSA-2574845
(
R-HSA-2565942
)
R-HSA-2574845
Reaction Name: AJUBA binds centrosome-associated AURKA
See in Reactome
R-HSA-265682
(
R-HSA-422356
)
R-HSA-265682
Reaction Name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel
See in Reactome
R-HSA-3000310
(
R-HSA-2565942
)
R-HSA-3000319
(
R-HSA-2565942
)
R-HSA-380272
(
R-HSA-380259;
R-HSA-380284
)
R-HSA-380272
Reaction Name: Plk1-mediated phosphorylation of Nlp
See in Reactome
R-HSA-380283
(
R-HSA-380270
)
R-HSA-380283
Reaction Name: Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome
See in Reactome
R-HSA-380294
(
R-HSA-380284
)
R-HSA-380294
Reaction Name: Loss of C-Nap-1 from centrosomes
See in Reactome
R-HSA-380303
(
R-HSA-380259;
R-HSA-380284
)
R-HSA-380303
Reaction Name: Dissociation of Phospho-Nlp from the centrosome
See in Reactome
R-HSA-380311
(
R-HSA-380270
)
R-HSA-380311
Reaction Name: Recruitment of Plk1 to centrosomes
See in Reactome
R-HSA-380316
(
R-HSA-380320;
R-HSA-68877
)
R-HSA-380316
Reaction Name: Association of NuMA with microtubules
See in Reactome
R-HSA-380455
(
R-HSA-380270
)
R-HSA-380455
Reaction Name: Recruitment of CDK11p58 to the centrosomes
See in Reactome
R-HSA-380508
(
R-HSA-380320;
R-HSA-68877
)
R-HSA-380508
Reaction Name: Translocation of NuMA to the centrosomes
See in Reactome
R-HSA-381644
(
R-HSA-381676;
R-HSA-422356
)
R-HSA-381644
Reaction Name: ER calcium channels open in response to activated PKA
See in Reactome
R-HSA-381707
(
R-HSA-381676;
R-HSA-422356
)
R-HSA-381707
Reaction Name: PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP
See in Reactome
R-HSA-381713
(
R-HSA-381676;
R-HSA-422356
)
R-HSA-381713
Reaction Name: Potassium voltage-gated channels close in reponse to PKA
See in Reactome
R-HSA-432232
(
R-HSA-432040
)
R-HSA-432232
Reaction Name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)
See in Reactome
R-HSA-5218854
(
R-HSA-4420097
)
R-HSA-5218854
Reaction Name: p-Y420-FYN is phosphorylated on S21
See in Reactome
R-HSA-5610717
(
R-HSA-5610783;
R-HSA-5610787
)
R-HSA-5610720
(
R-HSA-5610785;
R-HSA-5610787
)
R-HSA-5610741
(
R-HSA-5610780;
R-HSA-5610787
)
R-HSA-5610749
(
R-HSA-5610787
)
R-HSA-5610749
Reaction Name: cAMP dissociates PKA, promoting GLI processing
See in Reactome
R-HSA-5617179
(
R-HSA-5578775
)
R-HSA-5617182
(
R-HSA-5578775
)
R-HSA-5617816
(
R-HSA-5620912
)
R-HSA-5617816
Reaction Name: RAB3IP stimulates nucleotide exchange on RAB8A
See in Reactome
R-HSA-5624473
(
R-HSA-5621575
)
R-HSA-5624473
Reaction Name: Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit
See in Reactome
R-HSA-5626220
(
R-HSA-5620912
)
R-HSA-5626220
Reaction Name: C2CD3 binds the mother centriole
See in Reactome
R-HSA-5626223
(
R-HSA-5620912
)
R-HSA-5626223
Reaction Name: C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole
See in Reactome
R-HSA-5626227
(
R-HSA-5620912
)
R-HSA-5626227
Reaction Name: CP110 and CEP97 dissociate from the centriole
See in Reactome
R-HSA-5626228
(
R-HSA-5620912
)
R-HSA-5626228
Reaction Name: The distal appendage proteins recruit TTBK2
See in Reactome
R-HSA-5626681
(
R-HSA-5620912
)
R-HSA-5626681
Reaction Name: Recruitment of transition zone proteins
See in Reactome
R-HSA-5626699
(
R-HSA-5620912
)
R-HSA-5626699
Reaction Name: MARK4 binds ODF2 in the centriole
See in Reactome
R-HSA-5638009
(
R-HSA-5620912
)
R-HSA-5638009
Reaction Name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body
See in Reactome
R-HSA-5682101
(
R-HSA-8963896
)
R-HSA-5682101
Reaction Name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer
See in Reactome
R-HSA-5687088
(
R-HSA-5687128
)
R-HSA-8853405
(
R-HSA-8854518
)
R-HSA-8853405
Reaction Name: TPX2 binds AURKA at centrosomes
See in Reactome
R-HSA-8853419
(
R-HSA-8854518
)
R-HSA-8853419
Reaction Name: TPX2 promotes AURKA autophosphorylation
See in Reactome
R-HSA-8854908
(
R-HSA-8853659
)
R-HSA-8854908
Reaction Name: PKA phosphorylates RET:GDNF:GFRA dimer
See in Reactome
R-HSA-8951727
(
R-HSA-111931;
R-HSA-163615;
R-HSA-180024;
R-HSA-432040;
R-HSA-442720
)
R-HSA-8986937
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-8986937
Reaction Name: MECP2 is phosphorylated at T308
See in Reactome
R-HSA-8986939
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-8986939
Reaction Name: MECP2 binds the NCoR/SMRT complex
See in Reactome
R-HSA-9010641
(
R-HSA-9010642
)
R-HSA-913451
(
R-HSA-512988
)
R-HSA-913451
Reaction Name: IL3RB is phosphorylated on Ser-585
See in Reactome
R-HSA-913996
(
R-HSA-392517
)
R-HSA-992708
(
R-HSA-983231
)
R-HSA-992708
Reaction Name: Dual-specific AKAPs bind type I and II PKA regulatory subunits
See in Reactome
|
MONDO:0016996 |
AURKB |
Q96GD4 |
2.7.11.1
|
R-HSA-5663220
R-HSA-2500257
R-HSA-2500257
Reactome Name: Resolution of Sister Chromatid Cohesion
See in Reactome
R-HSA-2467813
R-HSA-2467813
Reactome Name: Separation of Sister Chromatids
See in Reactome
R-HSA-6804756
R-HSA-6804756
Reactome Name: Regulation of TP53 Activity through Phosphorylation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-4615885
R-HSA-4615885
Reactome Name: SUMOylation of DNA replication proteins
See in Reactome
R-HSA-9648025
R-HSA-9648025
Reactome Name: EML4 and NUDC in mitotic spindle formation
See in Reactome
R-HSA-174178
R-HSA-174178
Reactome Name: APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
See in Reactome
R-HSA-141444
R-HSA-141444
Reactome Name: Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
See in Reactome
R-HSA-68877
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-194315
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-73857
R-HSA-174143
R-HSA-174143
Reactome Name: APC/C-mediated degradation of cell cycle proteins
See in Reactome
R-HSA-5633007
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-69620
R-HSA-69278
R-HSA-2990846
R-HSA-141424
R-HSA-141424
Reactome Name: Amplification of signal from the kinetochores
See in Reactome
R-HSA-392499
R-HSA-453276
R-HSA-453276
Reactome Name: Regulation of mitotic cell cycle
See in Reactome
R-HSA-68886
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-195258
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-69618
R-HSA-162582
|
Cell Cycle
Gene expression (Transcription)
Metabolism of proteins
Signal Transduction
|
R-HSA-141409
(
R-HSA-141444
)
R-HSA-141422
(
R-HSA-141444
)
R-HSA-141422
Reaction Name: MAD2 converted to an inhibitory state via interaction with Mad1
See in Reactome
R-HSA-141431
(
R-HSA-141444
)
R-HSA-141431
Reaction Name: MAD2 associates with the Mad1 kinetochore complex
See in Reactome
R-HSA-141439
(
R-HSA-141444
)
R-HSA-141439
Reaction Name: Release of activated MAD2 from kinetochores
See in Reactome
R-HSA-1638803
(
R-HSA-2500257;
R-HSA-68877
)
R-HSA-1638803
Reaction Name: Phosphorylation of cohesin by PLK1 at centromeres
See in Reactome
R-HSA-1638821
(
R-HSA-2500257;
R-HSA-68877
)
R-HSA-1638821
Reaction Name: PP2A-B56 dephosphorylates centromeric cohesin
See in Reactome
R-HSA-174088
(
R-HSA-174178
)
R-HSA-174088
Reaction Name: Association of cell cycle proteins with the APC/C:Cdh1 complex
See in Reactome
R-HSA-174105
(
R-HSA-174178
)
R-HSA-174105
Reaction Name: Degradation of multiubiquitinated cell cycle proteins
See in Reactome
R-HSA-174195
(
R-HSA-174178
)
R-HSA-174195
Reaction Name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex
See in Reactome
R-HSA-2467809
(
R-HSA-2467813
)
R-HSA-2467809
Reaction Name: ESPL1 (Separase) cleaves centromeric cohesin
See in Reactome
R-HSA-2467811
(
R-HSA-2467813
)
R-HSA-2467811
Reaction Name: Separation of sister chromatids
See in Reactome
R-HSA-2468287
(
R-HSA-2500257;
R-HSA-68877
)
R-HSA-2468287
Reaction Name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres
See in Reactome
R-HSA-2484822
(
R-HSA-2500257;
R-HSA-68877
)
R-HSA-375302
(
R-HSA-68877
)
R-HSA-375302
Reaction Name: Kinetochore capture of astral microtubules
See in Reactome
R-HSA-4655355
(
R-HSA-4615885
)
R-HSA-4655355
Reaction Name: RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B)
See in Reactome
R-HSA-5666129
(
R-HSA-5663220
)
R-HSA-5666129
Reaction Name: CDC42:GTP recruits DIAPH2-2 to kinetochores
See in Reactome
R-HSA-5666160
(
R-HSA-5663220
)
R-HSA-5666160
Reaction Name: AURKB phosphorylates DIAPH2-2 at kinetochores
See in Reactome
R-HSA-5666169
(
R-HSA-5663220
)
R-HSA-5666169
Reaction Name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2
See in Reactome
R-HSA-6805122
(
R-HSA-6804756
)
R-HSA-6805126
(
R-HSA-6804756
)
R-HSA-9023132
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9023132
Reaction Name: AURKB phosphorylates MECP2 at S423
See in Reactome
R-HSA-9648114
(
R-HSA-68877;
R-HSA-9648025
)
R-HSA-9648114
Reaction Name: EML4 recruits NUDC to mitotic spindle
See in Reactome
|
MONDO:0018663 |
LBR |
Q14739 |
1.3.1.70
|
R-HSA-191273
R-HSA-9013106
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-8980692
R-HSA-9013408
R-HSA-9013423
R-HSA-9013404
R-HSA-9013405
R-HSA-9013149
R-HSA-9013148
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9012999
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-212436
R-HSA-74160
R-HSA-194315
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-556833
R-HSA-69278
R-HSA-1430728
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-1640170
R-HSA-8957322
R-HSA-162582
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Cell Cycle
Signal Transduction
|
R-HSA-194674
(
R-HSA-191273
)
R-HSA-194674
Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]
See in Reactome
R-HSA-9013004
(
R-HSA-8980692
)
R-HSA-9013004
Reaction Name: RHOA binds effectors at the ER membrane
See in Reactome
R-HSA-9013438
(
R-HSA-9013405
)
R-HSA-9013438
Reaction Name: RHOD binds effectors at the endosome membrane
See in Reactome
R-HSA-9014467
(
R-HSA-9013408
)
R-HSA-9014467
Reaction Name: RHOG binds effectors at the ER membrane
See in Reactome
R-HSA-9018594
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9624798
(
R-HSA-2995383
)
R-HSA-9624800
(
R-HSA-2995383
)
R-HSA-9691174
(
R-HSA-9013149
)
R-HSA-9691174
Reaction Name: RAC1 binds effectors at the ER membrane
See in Reactome
R-HSA-9692809
(
R-HSA-9013148
)
R-HSA-9692809
Reaction Name: CDC42 binds effectors at the ER membrane
See in Reactome
R-HSA-9714361
(
R-HSA-9013106
)
R-HSA-9714361
Reaction Name: RHOC activates endoplasmic reticulum effectors
See in Reactome
R-HSA-9714481
(
R-HSA-9013404
)
R-HSA-9714481
Reaction Name: RAC2 binds effectors at the ER membrane
See in Reactome
R-HSA-9714691
(
R-HSA-9013423
)
|
MONDO:0018770 |
MONDO:0018770
Disease Name: Jeune syndrome
OMIM id: OMIM:617088
Orphanet id: Orphanet:474
All associated enzymes in DAR:
LBR
. The disease is also associated to other non-enzyme proteins (not in DAR).
LBR |
Q14739 |
1.3.1.70
|
R-HSA-191273
R-HSA-9013106
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-8980692
R-HSA-9013408
R-HSA-9013423
R-HSA-9013404
R-HSA-9013405
R-HSA-9013149
R-HSA-9013148
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9012999
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-212436
R-HSA-74160
R-HSA-194315
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-556833
R-HSA-69278
R-HSA-1430728
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-1640170
R-HSA-8957322
R-HSA-162582
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Cell Cycle
Signal Transduction
|
R-HSA-194674
(
R-HSA-191273
)
R-HSA-194674
Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]
See in Reactome
R-HSA-9013004
(
R-HSA-8980692
)
R-HSA-9013004
Reaction Name: RHOA binds effectors at the ER membrane
See in Reactome
R-HSA-9013438
(
R-HSA-9013405
)
R-HSA-9013438
Reaction Name: RHOD binds effectors at the endosome membrane
See in Reactome
R-HSA-9014467
(
R-HSA-9013408
)
R-HSA-9014467
Reaction Name: RHOG binds effectors at the ER membrane
See in Reactome
R-HSA-9018594
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9624798
(
R-HSA-2995383
)
R-HSA-9624800
(
R-HSA-2995383
)
R-HSA-9691174
(
R-HSA-9013149
)
R-HSA-9691174
Reaction Name: RAC1 binds effectors at the ER membrane
See in Reactome
R-HSA-9692809
(
R-HSA-9013148
)
R-HSA-9692809
Reaction Name: CDC42 binds effectors at the ER membrane
See in Reactome
R-HSA-9714361
(
R-HSA-9013106
)
R-HSA-9714361
Reaction Name: RHOC activates endoplasmic reticulum effectors
See in Reactome
R-HSA-9714481
(
R-HSA-9013404
)
R-HSA-9714481
Reaction Name: RAC2 binds effectors at the ER membrane
See in Reactome
R-HSA-9714691
(
R-HSA-9013423
)
|
MONDO:0030876 |
PRKACA |
P17612 |
2.7.11.11
|
R-HSA-442720
R-HSA-442720
Reactome Name: CREB1 phosphorylation through the activation of Adenylate Cyclase
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-381676
R-HSA-381676
Reactome Name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
See in Reactome
R-HSA-380259
R-HSA-380259
Reactome Name: Loss of Nlp from mitotic centrosomes
See in Reactome
R-HSA-983231
R-HSA-983231
Reactome Name: Factors involved in megakaryocyte development and platelet production
See in Reactome
R-HSA-432040
R-HSA-432040
Reactome Name: Vasopressin regulates renal water homeostasis via Aquaporins
See in Reactome
R-HSA-380270
R-HSA-380270
Reactome Name: Recruitment of mitotic centrosome proteins and complexes
See in Reactome
R-HSA-5610783
R-HSA-5610783
Reactome Name: Degradation of GLI2 by the proteasome
See in Reactome
R-HSA-111931
R-HSA-111931
Reactome Name: PKA-mediated phosphorylation of CREB
See in Reactome
R-HSA-180024
R-HSA-5610787
R-HSA-163615
R-HSA-5610785
R-HSA-5610785
Reactome Name: GLI3 is processed to GLI3R by the proteasome
See in Reactome
R-HSA-164378
R-HSA-164378
Reactome Name: PKA activation in glucagon signalling
See in Reactome
R-HSA-5578775
R-HSA-8853659
R-HSA-9010642
R-HSA-8854518
R-HSA-4420097
R-HSA-380284
R-HSA-380284
Reactome Name: Loss of proteins required for interphase microtubule organization from the centrosome
See in Reactome
R-HSA-5687128
R-HSA-163560
R-HSA-5610780
R-HSA-5610780
Reactome Name: Degradation of GLI1 by the proteasome
See in Reactome
R-HSA-5620912
R-HSA-5620912
Reactome Name: Anchoring of the basal body to the plasma membrane
See in Reactome
R-HSA-512988
R-HSA-512988
Reactome Name: Interleukin-3, Interleukin-5 and GM-CSF signaling
See in Reactome
R-HSA-8963896
R-HSA-392517
R-HSA-163358
R-HSA-163358
Reactome Name: PKA-mediated phosphorylation of key metabolic factors
See in Reactome
R-HSA-422356
R-HSA-422356
Reactome Name: Regulation of insulin secretion
See in Reactome
R-HSA-2565942
R-HSA-2565942
Reactome Name: Regulation of PLK1 Activity at G2/M Transition
See in Reactome
R-HSA-380320
R-HSA-380320
Reactome Name: Recruitment of NuMA to mitotic centrosomes
See in Reactome
R-HSA-5621575
R-HSA-9634600
R-HSA-9634600
Reactome Name: Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
See in Reactome
|
R-HSA-376176
R-HSA-70326
R-HSA-111997
R-HSA-111996
R-HSA-397014
R-HSA-418594
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-168256
R-HSA-382551
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-9006925
R-HSA-9006925
Reactome Name: Intracellular signaling by second messengers
See in Reactome
R-HSA-1430728
R-HSA-5358351
R-HSA-1640170
R-HSA-5617833
R-HSA-1280218
R-HSA-1266738
R-HSA-1489509
R-HSA-111933
R-HSA-71387
R-HSA-163359
R-HSA-163359
Reactome Name: Glucagon signaling in metabolic regulation
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-1852241
R-HSA-1852241
Reactome Name: Organelle biogenesis and maintenance
See in Reactome
R-HSA-449147
R-HSA-9675108
R-HSA-69278
R-HSA-8979227
R-HSA-112316
R-HSA-372790
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-69275
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-5576891
R-HSA-556833
R-HSA-174824
R-HSA-174824
Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance
See in Reactome
R-HSA-388396
R-HSA-380287
R-HSA-168249
R-HSA-163685
R-HSA-163685
Reactome Name: Integration of energy metabolism
See in Reactome
R-HSA-445717
R-HSA-453274
R-HSA-68886
R-HSA-70171
R-HSA-8963898
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-112043
R-HSA-112040
R-HSA-73857
R-HSA-111885
R-HSA-109582
R-HSA-194138
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-68877
R-HSA-162582
|
Muscle contraction
Immune System
Transport of small molecules
Metabolism
Cell Cycle
Developmental Biology
Gene expression (Transcription)
Organelle biogenesis and maintenance
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-111919
(
R-HSA-111931;
R-HSA-442720
)
R-HSA-111924
(
R-HSA-111931;
R-HSA-442720
)
R-HSA-111924
Reaction Name: PKA catalytic subunit translocates to the nucleus
See in Reactome
R-HSA-111925
(
R-HSA-111931;
R-HSA-163615;
R-HSA-164378;
R-HSA-180024;
R-HSA-432040;
R-HSA-442720
)
R-HSA-111925
Reaction Name: cAMP induces dissociation of inactive PKA tetramers
See in Reactome
R-HSA-163416
(
R-HSA-163560
)
R-HSA-163416
Reaction Name: hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP
See in Reactome
R-HSA-163418
(
R-HSA-163560
)
R-HSA-163418
Reaction Name: perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP
See in Reactome
R-HSA-163672
(
R-HSA-163358
)
R-HSA-163672
Reaction Name: Phosphorylation of ChREBP at Thr(666) by PKA
See in Reactome
R-HSA-163676
(
R-HSA-163358
)
R-HSA-163676
Reaction Name: Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA
See in Reactome
R-HSA-163773
(
R-HSA-163358;
R-HSA-9634600
)
R-HSA-163773
Reaction Name: Phosphorylation of PF2K-Pase by PKA catalytic subunit
See in Reactome
R-HSA-177275
(
R-HSA-180024
)
R-HSA-177275
Reaction Name: PKA phosphorylates DARPP-32 on Thr34
See in Reactome
R-HSA-177284
(
R-HSA-180024
)
R-HSA-180073
(
R-HSA-180024
)
R-HSA-180073
Reaction Name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function
See in Reactome
R-HSA-2574840
(
R-HSA-2565942
)
R-HSA-2574840
Reaction Name: AJUBA facilitates AURKA autophosphorylation
See in Reactome
R-HSA-2574845
(
R-HSA-2565942
)
R-HSA-2574845
Reaction Name: AJUBA binds centrosome-associated AURKA
See in Reactome
R-HSA-265682
(
R-HSA-422356
)
R-HSA-265682
Reaction Name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel
See in Reactome
R-HSA-3000310
(
R-HSA-2565942
)
R-HSA-3000319
(
R-HSA-2565942
)
R-HSA-380272
(
R-HSA-380259;
R-HSA-380284
)
R-HSA-380272
Reaction Name: Plk1-mediated phosphorylation of Nlp
See in Reactome
R-HSA-380283
(
R-HSA-380270
)
R-HSA-380283
Reaction Name: Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome
See in Reactome
R-HSA-380294
(
R-HSA-380284
)
R-HSA-380294
Reaction Name: Loss of C-Nap-1 from centrosomes
See in Reactome
R-HSA-380303
(
R-HSA-380259;
R-HSA-380284
)
R-HSA-380303
Reaction Name: Dissociation of Phospho-Nlp from the centrosome
See in Reactome
R-HSA-380311
(
R-HSA-380270
)
R-HSA-380311
Reaction Name: Recruitment of Plk1 to centrosomes
See in Reactome
R-HSA-380316
(
R-HSA-380320;
R-HSA-68877
)
R-HSA-380316
Reaction Name: Association of NuMA with microtubules
See in Reactome
R-HSA-380455
(
R-HSA-380270
)
R-HSA-380455
Reaction Name: Recruitment of CDK11p58 to the centrosomes
See in Reactome
R-HSA-380508
(
R-HSA-380320;
R-HSA-68877
)
R-HSA-380508
Reaction Name: Translocation of NuMA to the centrosomes
See in Reactome
R-HSA-381644
(
R-HSA-381676;
R-HSA-422356
)
R-HSA-381644
Reaction Name: ER calcium channels open in response to activated PKA
See in Reactome
R-HSA-381707
(
R-HSA-381676;
R-HSA-422356
)
R-HSA-381707
Reaction Name: PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP
See in Reactome
R-HSA-381713
(
R-HSA-381676;
R-HSA-422356
)
R-HSA-381713
Reaction Name: Potassium voltage-gated channels close in reponse to PKA
See in Reactome
R-HSA-432232
(
R-HSA-432040
)
R-HSA-432232
Reaction Name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)
See in Reactome
R-HSA-5218854
(
R-HSA-4420097
)
R-HSA-5218854
Reaction Name: p-Y420-FYN is phosphorylated on S21
See in Reactome
R-HSA-5610717
(
R-HSA-5610783;
R-HSA-5610787
)
R-HSA-5610720
(
R-HSA-5610785;
R-HSA-5610787
)
R-HSA-5610741
(
R-HSA-5610780;
R-HSA-5610787
)
R-HSA-5610749
(
R-HSA-5610787
)
R-HSA-5610749
Reaction Name: cAMP dissociates PKA, promoting GLI processing
See in Reactome
R-HSA-5617179
(
R-HSA-5578775
)
R-HSA-5617182
(
R-HSA-5578775
)
R-HSA-5617816
(
R-HSA-5620912
)
R-HSA-5617816
Reaction Name: RAB3IP stimulates nucleotide exchange on RAB8A
See in Reactome
R-HSA-5624473
(
R-HSA-5621575
)
R-HSA-5624473
Reaction Name: Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit
See in Reactome
R-HSA-5626220
(
R-HSA-5620912
)
R-HSA-5626220
Reaction Name: C2CD3 binds the mother centriole
See in Reactome
R-HSA-5626223
(
R-HSA-5620912
)
R-HSA-5626223
Reaction Name: C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole
See in Reactome
R-HSA-5626227
(
R-HSA-5620912
)
R-HSA-5626227
Reaction Name: CP110 and CEP97 dissociate from the centriole
See in Reactome
R-HSA-5626228
(
R-HSA-5620912
)
R-HSA-5626228
Reaction Name: The distal appendage proteins recruit TTBK2
See in Reactome
R-HSA-5626681
(
R-HSA-5620912
)
R-HSA-5626681
Reaction Name: Recruitment of transition zone proteins
See in Reactome
R-HSA-5626699
(
R-HSA-5620912
)
R-HSA-5626699
Reaction Name: MARK4 binds ODF2 in the centriole
See in Reactome
R-HSA-5638009
(
R-HSA-5620912
)
R-HSA-5638009
Reaction Name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body
See in Reactome
R-HSA-5682101
(
R-HSA-8963896
)
R-HSA-5682101
Reaction Name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer
See in Reactome
R-HSA-5687088
(
R-HSA-5687128
)
R-HSA-8853405
(
R-HSA-8854518
)
R-HSA-8853405
Reaction Name: TPX2 binds AURKA at centrosomes
See in Reactome
R-HSA-8853419
(
R-HSA-8854518
)
R-HSA-8853419
Reaction Name: TPX2 promotes AURKA autophosphorylation
See in Reactome
R-HSA-8854908
(
R-HSA-8853659
)
R-HSA-8854908
Reaction Name: PKA phosphorylates RET:GDNF:GFRA dimer
See in Reactome
R-HSA-8951727
(
R-HSA-111931;
R-HSA-163615;
R-HSA-180024;
R-HSA-432040;
R-HSA-442720
)
R-HSA-8986937
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-8986937
Reaction Name: MECP2 is phosphorylated at T308
See in Reactome
R-HSA-8986939
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-8986939
Reaction Name: MECP2 binds the NCoR/SMRT complex
See in Reactome
R-HSA-9010641
(
R-HSA-9010642
)
R-HSA-913451
(
R-HSA-512988
)
R-HSA-913451
Reaction Name: IL3RB is phosphorylated on Ser-585
See in Reactome
R-HSA-913996
(
R-HSA-392517
)
R-HSA-992708
(
R-HSA-983231
)
R-HSA-992708
Reaction Name: Dual-specific AKAPs bind type I and II PKA regulatory subunits
See in Reactome
|
MONDO:0030897 |
AGO2 |
Q9UKV8 |
3.1.26.n2
|
R-HSA-8934593
R-HSA-8934593
Reactome Name: Regulation of RUNX1 Expression and Activity
See in Reactome
R-HSA-426486
R-HSA-426486
Reactome Name: Small interfering RNA (siRNA) biogenesis
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8943723
R-HSA-8943723
Reactome Name: Regulation of PTEN mRNA translation
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8948700
R-HSA-8948700
Reactome Name: Competing endogenous RNAs (ceRNAs) regulate PTEN translation
See in Reactome
R-HSA-203927
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-4086398
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-5578749
R-HSA-5578749
Reactome Name: Transcriptional regulation by small RNAs
See in Reactome
R-HSA-5628897
R-HSA-5628897
Reactome Name: TP53 Regulates Metabolic Genes
See in Reactome
R-HSA-426496
R-HSA-426496
Reactome Name: Post-transcriptional silencing by small RNAs
See in Reactome
R-HSA-5687128
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-195721
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-1257604
R-HSA-212436
R-HSA-74160
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-157118
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9006925
R-HSA-9006925
Reactome Name: Intracellular signaling by second messengers
See in Reactome
R-HSA-8939211
R-HSA-162582
R-HSA-6807070
R-HSA-211000
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-73857
|
Gene expression (Transcription)
Signal Transduction
|
R-HSA-1606561
(
R-HSA-1912408
)
R-HSA-1606561
Reaction Name: MIR449 microRNAs bind 3'UTR of NOTCH1 mRNA
See in Reactome
R-HSA-1606682
(
R-HSA-1912408
)
R-HSA-1606682
Reaction Name: MIR34 microRNAs bind 3'UTR of NOTCH1 mRNA
See in Reactome
R-HSA-1912362
(
R-HSA-1912408
)
R-HSA-1912362
Reaction Name: MIR150 microRNA binds 3'UTR of NOTCH3 mRNA
See in Reactome
R-HSA-1912363
(
R-HSA-1912408
)
R-HSA-1912363
Reaction Name: MIR200B/C microRNAs bind NOTCH1 mRNA
See in Reactome
R-HSA-1912364
(
R-HSA-1912408
)
R-HSA-1912364
Reaction Name: MIR181C microRNA binds 3'UTR of NOTCH4 mRNA
See in Reactome
R-HSA-1912366
(
R-HSA-1912408
)
R-HSA-1912366
Reaction Name: MIR206 microRNA binds 3'UTR of NOTCH3 mRNA
See in Reactome
R-HSA-1912367
(
R-HSA-1912408
)
R-HSA-1912367
Reaction Name: MIR34 microRNAs bind 3'UTR of NOTCH2 mRNA
See in Reactome
R-HSA-1912368
(
R-HSA-1912408
)
R-HSA-1912368
Reaction Name: MIR302A microRNA binds 3'UTR of NOTCH4 mRNA
See in Reactome
R-HSA-1912406
(
R-HSA-1912408
)
R-HSA-1912406
Reaction Name: p53 positively regulates transcription of MIR34 microRNAs
See in Reactome
R-HSA-1912409
(
R-HSA-1912408
)
R-HSA-1912409
Reaction Name: NOTCH3 mRNA translation controlled by miRNAs
See in Reactome
R-HSA-1912410
(
R-HSA-1912408
)
R-HSA-1912410
Reaction Name: NOTCH4 mRNA translation controlled by miRNAs
See in Reactome
R-HSA-1912412
(
R-HSA-1912408
)
R-HSA-1912412
Reaction Name: NOTCH1 mRNA translation controlled by miRNAs
See in Reactome
R-HSA-1912413
(
R-HSA-1912408
)
R-HSA-1912413
Reaction Name: NOTCH2 mRNA translation controlled by miRNAs
See in Reactome
R-HSA-203862
(
R-HSA-203927
)
R-HSA-203862
Reaction Name: Dicer cleaves pre-miRNA to yield duplex miRNA
See in Reactome
R-HSA-2106614
(
R-HSA-203927
)
R-HSA-2106614
Reaction Name: Duplex miRNA is loaded into Argonaute
See in Reactome
R-HSA-2106615
(
R-HSA-426486
)
R-HSA-2106615
Reaction Name: Removal of siRNA passenger strand
See in Reactome
R-HSA-2106625
(
R-HSA-426486
)
R-HSA-2106625
Reaction Name: Duplex siRNA is loaded into Argonaute
See in Reactome
R-HSA-210805
(
R-HSA-203927
)
R-HSA-210805
Reaction Name: Removal of miRNA passenger strand
See in Reactome
R-HSA-2318752
(
R-HSA-5628897;
R-HSA-8943723
)
R-HSA-2318752
Reaction Name: miR-26A microRNAs bind PTEN mRNA
See in Reactome
R-HSA-2321904
(
R-HSA-5628897
)
R-HSA-2321904
Reaction Name: PTEN mRNA translation negatively regulated by microRNAs
See in Reactome
R-HSA-426464
(
R-HSA-426486
)
R-HSA-426464
Reaction Name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA
See in Reactome
R-HSA-426489
(
R-HSA-426496
)
R-HSA-426489
Reaction Name: RISC binds inexactly matching target RNAs
See in Reactome
R-HSA-426520
(
R-HSA-426496
)
R-HSA-426520
Reaction Name: Endonucleolytic RISC hydrolyzes target RNAs
See in Reactome
R-HSA-4518575
(
R-HSA-4086398
)
R-HSA-4518575
Reaction Name: miR-92b binds 3'UTR of NLK mRNA
See in Reactome
R-HSA-4518585
(
R-HSA-4086398
)
R-HSA-4518585
Reaction Name: NLK mRNA translation controlled by miR-92b
See in Reactome
R-HSA-5578712
(
R-HSA-5578749
)
R-HSA-5578742
(
R-HSA-5578749
)
R-HSA-5578742
Reaction Name: AGO1,2:small RNA complexes interact with chromatin
See in Reactome
R-HSA-5578744
(
R-HSA-5578749
)
R-HSA-5578744
Reaction Name: Importin-8 imports AGO2:miRNA into the nucleus
See in Reactome
R-HSA-5578965
(
R-HSA-5578749
)
R-HSA-5578966
(
R-HSA-5578749
)
R-HSA-5578966
Reaction Name: TNRC6A:AGO2:miRNA is transported into the nucleus
See in Reactome
R-HSA-5687103
(
R-HSA-5687128
)
R-HSA-5687103
Reaction Name: FOXO3 regulates MIR34B,C expression
See in Reactome
R-HSA-5687113
(
R-HSA-5687128
)
R-HSA-5687113
Reaction Name: MYC mRNA translation is negatively regulated by miR-34B and C
See in Reactome
R-HSA-8935785
(
R-HSA-8934593
)
R-HSA-8935785
Reaction Name: RUNX1 mRNA translation is inhibited by miR-17, miR-18a, miR-20a, miR-27a, miR-106a, miR-215, miR-302b, miR-378 and miR-675
See in Reactome
R-HSA-8935864
(
R-HSA-8934593
)
R-HSA-8935930
(
R-HSA-8934593
)
R-HSA-8936058
(
R-HSA-8934593
)
R-HSA-8936068
(
R-HSA-8934593
)
R-HSA-8936068
Reaction Name: H19 is cleaved to produce miR-675
See in Reactome
R-HSA-8939129
(
R-HSA-8934593
)
R-HSA-8944483
(
R-HSA-8943723
)
R-HSA-8944483
Reaction Name: miR-17 microRNA binds PTEN mRNA
See in Reactome
R-HSA-8944497
(
R-HSA-8943723
)
R-HSA-8944497
Reaction Name: PTEN mRNA translation is negatively regulated by microRNAs
See in Reactome
R-HSA-8944522
(
R-HSA-8943723
)
R-HSA-8944522
Reaction Name: miR-19a microRNA binds PTEN mRNA
See in Reactome
R-HSA-8944538
(
R-HSA-8943723
)
R-HSA-8944538
Reaction Name: miR-22 microRNA binds PTEN mRNA
See in Reactome
R-HSA-8944569
(
R-HSA-8943723
)
R-HSA-8944569
Reaction Name: miR-25 microRNA binds PTEN mRNA
See in Reactome
R-HSA-8944599
(
R-HSA-8943723
)
R-HSA-8944599
Reaction Name: miR-93 microRNA binds PTEN mRNA
See in Reactome
R-HSA-8944632
(
R-HSA-8943723
)
R-HSA-8944632
Reaction Name: miR-106 microRNAs bind PTEN mRNA
See in Reactome
R-HSA-8944684
(
R-HSA-8943723
)
R-HSA-8944684
Reaction Name: miR-205 microRNA binds PTEN mRNA
See in Reactome
R-HSA-8945709
(
R-HSA-8943723
)
R-HSA-8945709
Reaction Name: miR-20 microRNAs bind PTEN mRNA
See in Reactome
R-HSA-8948524
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948524
Reaction Name: PTENP1 mRNA binds miR-19b RISC
See in Reactome
R-HSA-8948536
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948569
(
R-HSA-8943723
)
R-HSA-8948569
Reaction Name: miR-19b microRNA binds PTEN mRNA
See in Reactome
R-HSA-8948582
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948582
Reaction Name: miR-17 microRNA binds VAPA mRNA
See in Reactome
R-HSA-8948583
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948583
Reaction Name: miR-17 microRNA binds CNOT6L mRNA
See in Reactome
R-HSA-8948594
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948594
Reaction Name: miR-19a microRNA binds VAPA mRNA
See in Reactome
R-HSA-8948602
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948602
Reaction Name: miR-19a microRNA binds CNOT6L mRNA
See in Reactome
R-HSA-8948612
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948612
Reaction Name: miR-19b microRNA binds CNOT6L mRNA
See in Reactome
R-HSA-8948621
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948621
Reaction Name: miR-20 microRNAs bind VAPA mRNA
See in Reactome
R-HSA-8948623
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948623
Reaction Name: miR-20 microRNAs bind CNOT6L mRNA
See in Reactome
R-HSA-8948641
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948641
Reaction Name: miR-106 microRNAs bind VAPA mRNA
See in Reactome
R-HSA-8948651
(
R-HSA-8943723;
R-HSA-8948700
)
R-HSA-8948651
Reaction Name: miR-106a,(miR106b) microRNA binds CNOT6L mRNA
See in Reactome
R-HSA-9011958
(
R-HSA-9018519
)
R-HSA-9011958
Reaction Name: miR-26A and B bind to the 3'UTR of the GREB1 mRNA
See in Reactome
R-HSA-9011961
(
R-HSA-9018519
)
R-HSA-9011961
Reaction Name: GREB1 translation is negatively regulated by miR-26A and B
See in Reactome
R-HSA-9012186
(
R-HSA-9018519
)
R-HSA-9012186
Reaction Name: CHD1 translation is negatively regulated by miR-26A and B
See in Reactome
R-HSA-9012196
(
R-HSA-9018519
)
R-HSA-9012196
Reaction Name: KPNA2 translation is negatively regulated by miR-26A and B
See in Reactome
R-HSA-9012203
(
R-HSA-9018519
)
R-HSA-9012203
Reaction Name: miR-26A and B bind to the 3'UTR of the CHD11 mRNA
See in Reactome
R-HSA-9012208
(
R-HSA-9018519
)
R-HSA-9012208
Reaction Name: miR-26A and B bind to the 3'UTR of the KPNA2 mRNA
See in Reactome
R-HSA-9021182
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9021183
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9021183
Reaction Name: MECP2 mRNA translation is inhibited by miR-132
See in Reactome
R-HSA-9023909
(
R-HSA-426486
)
R-HSA-9023909
Reaction Name: C3PO hydrolyzes cleaved passenger strand
See in Reactome
R-HSA-9023912
(
R-HSA-426486
)
R-HSA-9023912
Reaction Name: AGO2 cleaves passenger strand of duplex siRNA
See in Reactome
R-HSA-9038545
(
R-HSA-9029569
)
R-HSA-9038545
Reaction Name: miR-613 binds to the 3'UTR of the NR1H3 mRNA
See in Reactome
R-HSA-9605052
(
R-HSA-9029569
)
R-HSA-9615501
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9615501
Reaction Name: MIR132 gene expression is stimulated by p-S133-CREB1
See in Reactome
R-HSA-9615554
(
R-HSA-8986944
)
R-HSA-9615554
Reaction Name: MIR137 gene expression is inhibited by MECP2 and SOX2
See in Reactome
R-HSA-9615570
(
R-HSA-8986944
)
R-HSA-9615571
(
R-HSA-8986944
)
R-HSA-9615571
Reaction Name: PTEN mRNA translation is inhibited by miR-137
See in Reactome
R-HSA-9618392
(
R-HSA-9029569
)
R-HSA-9618392
Reaction Name: miR-26 binds to the 3'UTR of the ARL4C mRNA
See in Reactome
R-HSA-9618405
(
R-HSA-9029569
)
R-HSA-9618479
(
R-HSA-9029569
)
R-HSA-9618486
(
R-HSA-9029569
)
R-HSA-9618486
Reaction Name: miR-26 binds to the 3'UTR of the ABCA1 mRNA
See in Reactome
R-HSA-9624925
(
R-HSA-9029569
)
R-HSA-9624925
Reaction Name: miR-33 binds to the 3'UTR of the ABCA1 mRNA
See in Reactome
R-HSA-9657791
(
R-HSA-9029569
)
R-HSA-9657791
Reaction Name: miR-144 binds to the 3'UTR of the ABCA1 mRNA
See in Reactome
|
MONDO:0030919 |
CAMK2A |
Q9UQM7 |
2.7.11.17
|
R-HSA-111932
R-HSA-111932
Reactome Name: CaMK IV-mediated phosphorylation of CREB
See in Reactome
R-HSA-9617324
R-HSA-9617324
Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission
See in Reactome
R-HSA-5576892
R-HSA-5576892
Reactome Name: Phase 0 - rapid depolarisation
See in Reactome
R-HSA-9620244
R-HSA-5578775
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-399719
R-HSA-4086398
R-HSA-877300
R-HSA-438066
R-HSA-438066
Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation
See in Reactome
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-936837
R-HSA-936837
Reactome Name: Ion transport by P-type ATPases
See in Reactome
R-HSA-9609736
R-HSA-9609736
Reactome Name: Assembly and cell surface presentation of NMDA receptors
See in Reactome
R-HSA-5673000
R-HSA-5673001
|
R-HSA-1489509
R-HSA-111997
R-HSA-111996
R-HSA-397014
R-HSA-418594
R-HSA-168256
R-HSA-382551
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-9006925
R-HSA-9006925
Reactome Name: Intracellular signaling by second messengers
See in Reactome
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-5684996
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-73857
R-HSA-111933
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-2262752
R-HSA-112316
R-HSA-372790
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-983712
R-HSA-5576891
R-HSA-8953897
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-913531
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-399721
R-HSA-399721
Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity
See in Reactome
R-HSA-195721
R-HSA-112043
R-HSA-112040
R-HSA-111885
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-162582
|
Muscle contraction
Immune System
Transport of small molecules
Gene expression (Transcription)
Neuronal System
Cellular responses to stimuli
Signal Transduction
|
R-HSA-416320
(
R-HSA-399719
)
R-HSA-416320
Reaction Name: Trafficking of GluR1-containing AMPA receptors
See in Reactome
R-HSA-427910
(
R-HSA-5578775;
R-HSA-936837
)
R-HSA-427910
Reaction Name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen
See in Reactome
R-HSA-432162
(
R-HSA-438066
)
R-HSA-432162
Reaction Name: Unblocking of GRIN1:GRIN2 NMDA receptors
See in Reactome
R-HSA-432164
(
R-HSA-438066
)
R-HSA-432164
Reaction Name: Ca2+ influx into the post-synaptic cell
See in Reactome
R-HSA-432172
(
R-HSA-438066
)
R-HSA-432172
Reaction Name: Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor
See in Reactome
R-HSA-4332356
(
R-HSA-4086398
)
R-HSA-4332358
(
R-HSA-4086398
)
R-HSA-4332358
Reaction Name: Dissociation of CaM and CAMK2 autophosphorylation
See in Reactome
R-HSA-4332359
(
R-HSA-4086398
)
R-HSA-4332363
(
R-HSA-4086398
)
R-HSA-4332363
Reaction Name: Autophosphorylation and activation of CAMK2
See in Reactome
R-HSA-4332388
(
R-HSA-4086398
)
R-HSA-4332388
Reaction Name: Activation of MAP3K7 in response to WNT
See in Reactome
R-HSA-438037
(
R-HSA-438066
)
R-HSA-438037
Reaction Name: Membrane depolarization upon activation of Ca impermeable AMPA receptors
See in Reactome
R-HSA-442725
(
R-HSA-111932;
R-HSA-9620244
)
R-HSA-442725
Reaction Name: CaMKII binds activated calmodulin
See in Reactome
R-HSA-442732
(
R-HSA-442982
)
R-HSA-442732
Reaction Name: NMDA-activated RASGRF1 activates RAS
See in Reactome
R-HSA-442760
(
R-HSA-442982
)
R-HSA-445367
(
R-HSA-9620244
)
R-HSA-445367
Reaction Name: CaMKII binds activated NMDA receptor
See in Reactome
R-HSA-5082387
(
R-HSA-3371571
)
R-HSA-5082387
Reaction Name: Phosphorylation of HSF1 at Ser230 induces transactivation
See in Reactome
R-HSA-5576895
(
R-HSA-5576892
)
R-HSA-5576895
Reaction Name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol
See in Reactome
R-HSA-5672965
(
R-HSA-5673001
)
R-HSA-5672965
Reaction Name: RAS GEFs promote RAS nucleotide exchange
See in Reactome
R-HSA-5672969
(
R-HSA-5673000;
R-HSA-5673001
)
R-HSA-9006992
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9006992
Reaction Name: MECP2 is phosphorylated at S423
See in Reactome
R-HSA-909552
(
R-HSA-877300
)
R-HSA-909552
Reaction Name: Phosphorylation of STAT1 at Ser727
See in Reactome
R-HSA-9611368
(
R-HSA-9609736
)
R-HSA-9611368
Reaction Name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density
See in Reactome
R-HSA-9612085
(
R-HSA-9620244
)
R-HSA-9612085
Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs
See in Reactome
R-HSA-9614185
(
R-HSA-438066
)
R-HSA-9614185
Reaction Name: Mg2+ binds GRIN1:GRIN2 NMDA receptors
See in Reactome
R-HSA-9617326
(
R-HSA-9617324
)
R-HSA-9617326
Reaction Name: CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2
See in Reactome
R-HSA-9617583
(
R-HSA-111932;
R-HSA-9620244
)
R-HSA-9618750
(
R-HSA-9620244
)
R-HSA-9618750
Reaction Name: CaMKII phosphorylates AMPA receptor
See in Reactome
R-HSA-9619449
(
R-HSA-9617324
)
R-HSA-9619449
Reaction Name: PPM1F dephosphorylates p-T286-CaMKII
See in Reactome
|
MONDO:0030920 |
CAMK2B |
Q13554 |
2.7.11.17
|
R-HSA-442729
R-HSA-442729
Reactome Name: CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde
See in Reactome
R-HSA-111932
R-HSA-111932
Reactome Name: CaMK IV-mediated phosphorylation of CREB
See in Reactome
R-HSA-9617324
R-HSA-9617324
Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission
See in Reactome
R-HSA-5576892
R-HSA-5576892
Reactome Name: Phase 0 - rapid depolarisation
See in Reactome
R-HSA-9620244
R-HSA-5578775
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-399719
R-HSA-877300
R-HSA-438066
R-HSA-438066
Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation
See in Reactome
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-936837
R-HSA-936837
Reactome Name: Ion transport by P-type ATPases
See in Reactome
R-HSA-9609736
R-HSA-9609736
Reactome Name: Assembly and cell surface presentation of NMDA receptors
See in Reactome
R-HSA-5673000
R-HSA-5673001
|
R-HSA-1489509
R-HSA-111997
R-HSA-111996
R-HSA-397014
R-HSA-418594
R-HSA-168256
R-HSA-382551
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-9006925
R-HSA-9006925
Reactome Name: Intracellular signaling by second messengers
See in Reactome
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-5684996
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-73857
R-HSA-111933
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-2262752
R-HSA-112316
R-HSA-372790
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5576891
R-HSA-8953897
R-HSA-388396
R-HSA-983712
R-HSA-913531
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-399721
R-HSA-399721
Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity
See in Reactome
R-HSA-112043
R-HSA-112040
R-HSA-111885
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-162582
|
Muscle contraction
Immune System
Transport of small molecules
Gene expression (Transcription)
Neuronal System
Cellular responses to stimuli
Signal Transduction
|
R-HSA-416320
(
R-HSA-399719
)
R-HSA-416320
Reaction Name: Trafficking of GluR1-containing AMPA receptors
See in Reactome
R-HSA-427910
(
R-HSA-5578775;
R-HSA-936837
)
R-HSA-427910
Reaction Name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen
See in Reactome
R-HSA-432162
(
R-HSA-438066
)
R-HSA-432162
Reaction Name: Unblocking of GRIN1:GRIN2 NMDA receptors
See in Reactome
R-HSA-432164
(
R-HSA-438066
)
R-HSA-432164
Reaction Name: Ca2+ influx into the post-synaptic cell
See in Reactome
R-HSA-432172
(
R-HSA-438066
)
R-HSA-432172
Reaction Name: Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor
See in Reactome
R-HSA-438037
(
R-HSA-438066
)
R-HSA-438037
Reaction Name: Membrane depolarization upon activation of Ca impermeable AMPA receptors
See in Reactome
R-HSA-442725
(
R-HSA-111932;
R-HSA-9620244
)
R-HSA-442725
Reaction Name: CaMKII binds activated calmodulin
See in Reactome
R-HSA-442732
(
R-HSA-442982
)
R-HSA-442732
Reaction Name: NMDA-activated RASGRF1 activates RAS
See in Reactome
R-HSA-442760
(
R-HSA-442982
)
R-HSA-444792
(
R-HSA-111932;
R-HSA-442729
)
R-HSA-444792
Reaction Name: Calmodulin-bound CaMKII-gamma enters the nucleus
See in Reactome
R-HSA-445367
(
R-HSA-9620244
)
R-HSA-445367
Reaction Name: CaMKII binds activated NMDA receptor
See in Reactome
R-HSA-5082387
(
R-HSA-3371571
)
R-HSA-5082387
Reaction Name: Phosphorylation of HSF1 at Ser230 induces transactivation
See in Reactome
R-HSA-5576895
(
R-HSA-5576892
)
R-HSA-5576895
Reaction Name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol
See in Reactome
R-HSA-5672965
(
R-HSA-5673001
)
R-HSA-5672965
Reaction Name: RAS GEFs promote RAS nucleotide exchange
See in Reactome
R-HSA-5672969
(
R-HSA-5673000;
R-HSA-5673001
)
R-HSA-9006992
(
R-HSA-8986944;
R-HSA-9022692
)
R-HSA-9006992
Reaction Name: MECP2 is phosphorylated at S423
See in Reactome
R-HSA-909552
(
R-HSA-877300
)
R-HSA-909552
Reaction Name: Phosphorylation of STAT1 at Ser727
See in Reactome
R-HSA-9611368
(
R-HSA-9609736
)
R-HSA-9611368
Reaction Name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density
See in Reactome
R-HSA-9612085
(
R-HSA-9620244
)
R-HSA-9612085
Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs
See in Reactome
R-HSA-9614185
(
R-HSA-438066
)
R-HSA-9614185
Reaction Name: Mg2+ binds GRIN1:GRIN2 NMDA receptors
See in Reactome
R-HSA-9617326
(
R-HSA-9617324
)
R-HSA-9617326
Reaction Name: CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2
See in Reactome
R-HSA-9617583
(
R-HSA-111932;
R-HSA-9620244
)
R-HSA-9618750
(
R-HSA-9620244
)
R-HSA-9618750
Reaction Name: CaMKII phosphorylates AMPA receptor
See in Reactome
R-HSA-9619449
(
R-HSA-9617324
)
R-HSA-9619449
Reaction Name: PPM1F dephosphorylates p-T286-CaMKII
See in Reactome
|
MONDO:0032795 |
CAMK2G |
Q13555 |
2.7.11.17
|
R-HSA-442729
R-HSA-442729
Reactome Name: CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde
See in Reactome
R-HSA-111932
R-HSA-111932
Reactome Name: CaMK IV-mediated phosphorylation of CREB
See in Reactome
R-HSA-9617324
R-HSA-9617324
Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission
See in Reactome
R-HSA-5576892
R-HSA-5576892
Reactome Name: Phase 0 - rapid depolarisation
See in Reactome
R-HSA-9620244
R-HSA-5578775
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-399719
R-HSA-877300
R-HSA-438066
R-HSA-438066
Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation
See in Reactome
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-936837
R-HSA-936837
Reactome Name: Ion transport by P-type ATPases
See in Reactome
R-HSA-9609736
R-HSA-9609736
Reactome Name: Assembly and cell surface presentation of NMDA receptors
See in Reactome
R-HSA-5673000
R-HSA-5673001
|
R-HSA-1489509
R-HSA-111997
R-HSA-111996
R-HSA-397014
R-HSA-418594
R-HSA-168256
R-HSA-382551
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-9006925
R-HSA-9006925
Reactome Name: Intracellular signaling by second messengers
See in Reactome
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-5684996
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-73857
R-HSA-111933
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-2262752
R-HSA-112316
R-HSA-372790
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5576891
R-HSA-8953897
R-HSA-388396
R-HSA-983712
R-HSA-913531
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-399721
R-HSA-399721
Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity
See in Reactome
R-HSA-112043
R-HSA-112040
R-HSA-111885
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-162582
|
Muscle contraction
Immune System
Transport of small molecules
Gene expression (Transcription)
Neuronal System
Cellular responses to stimuli
Signal Transduction
|
R-HSA-416320
(
R-HSA-399719
)
R-HSA-416320
Reaction Name: Trafficking of GluR1-containing AMPA receptors
See in Reactome
|