DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-9022692)

Number of enzymes:	7
Number of disease:	13
Number of reactomes:	79
Number of reactions:	201

Search results (Reactome ID: R-HSA-9022692)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008214	LBR	Q14739	1.3.1.70	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-2995383 R-HSA-2995383 Reactome Name: Initiation of Nuclear Envelope (NE) Reformation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-2995410 R-HSA-2995410 Reactome Name: Nuclear Envelope (NE) Reassembly See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Cell Cycle Signal Transduction	R-HSA-194674 ( R-HSA-191273 ) R-HSA-194674 Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] See in Reactome R-HSA-9013004 ( R-HSA-8980692 ) R-HSA-9013004 Reaction Name: RHOA binds effectors at the ER membrane See in Reactome R-HSA-9013438 ( R-HSA-9013405 ) R-HSA-9013438 Reaction Name: RHOD binds effectors at the endosome membrane See in Reactome R-HSA-9014467 ( R-HSA-9013408 ) R-HSA-9014467 Reaction Name: RHOG binds effectors at the ER membrane See in Reactome R-HSA-9018594 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9018594 Reaction Name: MECP2 binds LBR See in Reactome R-HSA-9624798 ( R-HSA-2995383 ) R-HSA-9624798 Reaction Name: LBR binds KPNB1 See in Reactome R-HSA-9624800 ( R-HSA-2995383 ) R-HSA-9624800 Reaction Name: CDK1 phosphorylates LBR See in Reactome R-HSA-9691174 ( R-HSA-9013149 ) R-HSA-9691174 Reaction Name: RAC1 binds effectors at the ER membrane See in Reactome R-HSA-9692809 ( R-HSA-9013148 ) R-HSA-9692809 Reaction Name: CDC42 binds effectors at the ER membrane See in Reactome R-HSA-9714361 ( R-HSA-9013106 ) R-HSA-9714361 Reaction Name: RHOC activates endoplasmic reticulum effectors See in Reactome R-HSA-9714481 ( R-HSA-9013404 ) R-HSA-9714481 Reaction Name: RAC2 binds effectors at the ER membrane See in Reactome R-HSA-9714691 ( R-HSA-9013423 ) R-HSA-9714691 Reaction Name: RAC3 binds ER effectors See in Reactome
MONDO:0008974	LBR	Q14739	1.3.1.70	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-2995383 R-HSA-2995383 Reactome Name: Initiation of Nuclear Envelope (NE) Reformation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-2995410 R-HSA-2995410 Reactome Name: Nuclear Envelope (NE) Reassembly See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Cell Cycle Signal Transduction	R-HSA-194674 ( R-HSA-191273 ) R-HSA-194674 Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] See in Reactome R-HSA-9013004 ( R-HSA-8980692 ) R-HSA-9013004 Reaction Name: RHOA binds effectors at the ER membrane See in Reactome R-HSA-9013438 ( R-HSA-9013405 ) R-HSA-9013438 Reaction Name: RHOD binds effectors at the endosome membrane See in Reactome R-HSA-9014467 ( R-HSA-9013408 ) R-HSA-9014467 Reaction Name: RHOG binds effectors at the ER membrane See in Reactome R-HSA-9018594 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9018594 Reaction Name: MECP2 binds LBR See in Reactome R-HSA-9624798 ( R-HSA-2995383 ) R-HSA-9624798 Reaction Name: LBR binds KPNB1 See in Reactome R-HSA-9624800 ( R-HSA-2995383 ) R-HSA-9624800 Reaction Name: CDK1 phosphorylates LBR See in Reactome R-HSA-9691174 ( R-HSA-9013149 ) R-HSA-9691174 Reaction Name: RAC1 binds effectors at the ER membrane See in Reactome R-HSA-9692809 ( R-HSA-9013148 ) R-HSA-9692809 Reaction Name: CDC42 binds effectors at the ER membrane See in Reactome R-HSA-9714361 ( R-HSA-9013106 ) R-HSA-9714361 Reaction Name: RHOC activates endoplasmic reticulum effectors See in Reactome R-HSA-9714481 ( R-HSA-9013404 ) R-HSA-9714481 Reaction Name: RAC2 binds effectors at the ER membrane See in Reactome R-HSA-9714691 ( R-HSA-9013423 ) R-HSA-9714691 Reaction Name: RAC3 binds ER effectors See in Reactome
MONDO:0013276	LBR	Q14739	1.3.1.70	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-2995383 R-HSA-2995383 Reactome Name: Initiation of Nuclear Envelope (NE) Reformation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-2995410 R-HSA-2995410 Reactome Name: Nuclear Envelope (NE) Reassembly See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Cell Cycle Signal Transduction	R-HSA-194674 ( R-HSA-191273 ) R-HSA-194674 Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] See in Reactome R-HSA-9013004 ( R-HSA-8980692 ) R-HSA-9013004 Reaction Name: RHOA binds effectors at the ER membrane See in Reactome R-HSA-9013438 ( R-HSA-9013405 ) R-HSA-9013438 Reaction Name: RHOD binds effectors at the endosome membrane See in Reactome R-HSA-9014467 ( R-HSA-9013408 ) R-HSA-9014467 Reaction Name: RHOG binds effectors at the ER membrane See in Reactome R-HSA-9018594 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9018594 Reaction Name: MECP2 binds LBR See in Reactome R-HSA-9624798 ( R-HSA-2995383 ) R-HSA-9624798 Reaction Name: LBR binds KPNB1 See in Reactome R-HSA-9624800 ( R-HSA-2995383 ) R-HSA-9624800 Reaction Name: CDK1 phosphorylates LBR See in Reactome R-HSA-9691174 ( R-HSA-9013149 ) R-HSA-9691174 Reaction Name: RAC1 binds effectors at the ER membrane See in Reactome R-HSA-9692809 ( R-HSA-9013148 ) R-HSA-9692809 Reaction Name: CDC42 binds effectors at the ER membrane See in Reactome R-HSA-9714361 ( R-HSA-9013106 ) R-HSA-9714361 Reaction Name: RHOC activates endoplasmic reticulum effectors See in Reactome R-HSA-9714481 ( R-HSA-9013404 ) R-HSA-9714481 Reaction Name: RAC2 binds effectors at the ER membrane See in Reactome R-HSA-9714691 ( R-HSA-9013423 ) R-HSA-9714691 Reaction Name: RAC3 binds ER effectors See in Reactome
MONDO:0014359	PRKACA	P17612	2.7.11.11	R-HSA-442720 R-HSA-442720 Reactome Name: CREB1 phosphorylation through the activation of Adenylate Cyclase See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-381676 R-HSA-381676 Reactome Name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion See in Reactome R-HSA-380259 R-HSA-380259 Reactome Name: Loss of Nlp from mitotic centrosomes See in Reactome R-HSA-983231 R-HSA-983231 Reactome Name: Factors involved in megakaryocyte development and platelet production See in Reactome R-HSA-432040 R-HSA-432040 Reactome Name: Vasopressin regulates renal water homeostasis via Aquaporins See in Reactome R-HSA-380270 R-HSA-380270 Reactome Name: Recruitment of mitotic centrosome proteins and complexes See in Reactome R-HSA-5610783 R-HSA-5610783 Reactome Name: Degradation of GLI2 by the proteasome See in Reactome R-HSA-111931 R-HSA-111931 Reactome Name: PKA-mediated phosphorylation of CREB See in Reactome R-HSA-180024 R-HSA-180024 Reactome Name: DARPP-32 events See in Reactome R-HSA-5610787 R-HSA-5610787 Reactome Name: Hedgehog 'off' state See in Reactome R-HSA-163615 R-HSA-163615 Reactome Name: PKA activation See in Reactome R-HSA-5610785 R-HSA-5610785 Reactome Name: GLI3 is processed to GLI3R by the proteasome See in Reactome R-HSA-164378 R-HSA-164378 Reactome Name: PKA activation in glucagon signalling See in Reactome R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-8853659 R-HSA-8853659 Reactome Name: RET signaling See in Reactome R-HSA-9010642 R-HSA-9010642 Reactome Name: ROBO receptors bind AKAP5 See in Reactome R-HSA-8854518 R-HSA-8854518 Reactome Name: AURKA Activation by TPX2 See in Reactome R-HSA-4420097 R-HSA-4420097 Reactome Name: VEGFA-VEGFR2 Pathway See in Reactome R-HSA-380284 R-HSA-380284 Reactome Name: Loss of proteins required for interphase microtubule organization from the centrosome See in Reactome R-HSA-5687128 R-HSA-5687128 Reactome Name: MAPK6/MAPK4 signaling See in Reactome R-HSA-163560 R-HSA-163560 Reactome Name: Triglyceride catabolism See in Reactome R-HSA-5610780 R-HSA-5610780 Reactome Name: Degradation of GLI1 by the proteasome See in Reactome R-HSA-5620912 R-HSA-5620912 Reactome Name: Anchoring of the basal body to the plasma membrane See in Reactome R-HSA-512988 R-HSA-512988 Reactome Name: Interleukin-3, Interleukin-5 and GM-CSF signaling See in Reactome R-HSA-8963896 R-HSA-8963896 Reactome Name: HDL assembly See in Reactome R-HSA-392517 R-HSA-392517 Reactome Name: Rap1 signalling See in Reactome R-HSA-163358 R-HSA-163358 Reactome Name: PKA-mediated phosphorylation of key metabolic factors See in Reactome R-HSA-422356 R-HSA-422356 Reactome Name: Regulation of insulin secretion See in Reactome R-HSA-2565942 R-HSA-2565942 Reactome Name: Regulation of PLK1 Activity at G2/M Transition See in Reactome R-HSA-380320 R-HSA-380320 Reactome Name: Recruitment of NuMA to mitotic centrosomes See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9634600 R-HSA-9634600 Reactome Name: Regulation of glycolysis by fructose 2,6-bisphosphate metabolism See in Reactome	R-HSA-376176 R-HSA-376176 Reactome Name: Signaling by ROBO receptors See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-5358351 R-HSA-5358351 Reactome Name: Signaling by Hedgehog See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-5617833 R-HSA-5617833 Reactome Name: Cilium Assembly See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-163359 R-HSA-163359 Reactome Name: Glucagon signaling in metabolic regulation See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-1852241 R-HSA-1852241 Reactome Name: Organelle biogenesis and maintenance See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-380287 R-HSA-380287 Reactome Name: Centrosome maturation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-445717 R-HSA-445717 Reactome Name: Aquaporin-mediated transport See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome R-HSA-8963898 R-HSA-8963898 Reactome Name: Plasma lipoprotein assembly See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-68877 R-HSA-68877 Reactome Name: Mitotic Prometaphase See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Muscle contraction Immune System Transport of small molecules Metabolism Cell Cycle Developmental Biology Gene expression (Transcription) Organelle biogenesis and maintenance Neuronal System Hemostasis Signal Transduction	R-HSA-111919 ( R-HSA-111931; R-HSA-442720 ) R-HSA-111919 Reaction Name: PKA phosphorylates CREB1 See in Reactome R-HSA-111924 ( R-HSA-111931; R-HSA-442720 ) R-HSA-111924 Reaction Name: PKA catalytic subunit translocates to the nucleus See in Reactome R-HSA-111925 ( R-HSA-111931; R-HSA-163615; R-HSA-164378; R-HSA-180024; R-HSA-432040; R-HSA-442720 ) R-HSA-111925 Reaction Name: cAMP induces dissociation of inactive PKA tetramers See in Reactome R-HSA-163416 ( R-HSA-163560 ) R-HSA-163416 Reaction Name: hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP See in Reactome R-HSA-163418 ( R-HSA-163560 ) R-HSA-163418 Reaction Name: perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP See in Reactome R-HSA-163672 ( R-HSA-163358 ) R-HSA-163672 Reaction Name: Phosphorylation of ChREBP at Thr(666) by PKA See in Reactome R-HSA-163676 ( R-HSA-163358 ) R-HSA-163676 Reaction Name: Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA See in Reactome R-HSA-163773 ( R-HSA-163358; R-HSA-9634600 ) R-HSA-163773 Reaction Name: Phosphorylation of PF2K-Pase by PKA catalytic subunit See in Reactome R-HSA-177275 ( R-HSA-180024 ) R-HSA-177275 Reaction Name: PKA phosphorylates DARPP-32 on Thr34 See in Reactome R-HSA-177284 ( R-HSA-180024 ) R-HSA-177284 Reaction Name: PKA phosphorylates PDE4B See in Reactome R-HSA-180073 ( R-HSA-180024 ) R-HSA-180073 Reaction Name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function See in Reactome R-HSA-2574840 ( R-HSA-2565942 ) R-HSA-2574840 Reaction Name: AJUBA facilitates AURKA autophosphorylation See in Reactome R-HSA-2574845 ( R-HSA-2565942 ) R-HSA-2574845 Reaction Name: AJUBA binds centrosome-associated AURKA See in Reactome R-HSA-265682 ( R-HSA-422356 ) R-HSA-265682 Reaction Name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel See in Reactome R-HSA-3000310 ( R-HSA-2565942 ) R-HSA-3000310 Reaction Name: AURKA phosphorylates PLK1 See in Reactome R-HSA-3000319 ( R-HSA-2565942 ) R-HSA-3000319 Reaction Name: BORA binds PLK1 and AURKA See in Reactome R-HSA-380272 ( R-HSA-380259; R-HSA-380284 ) R-HSA-380272 Reaction Name: Plk1-mediated phosphorylation of Nlp See in Reactome R-HSA-380283 ( R-HSA-380270 ) R-HSA-380283 Reaction Name: Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome See in Reactome R-HSA-380294 ( R-HSA-380284 ) R-HSA-380294 Reaction Name: Loss of C-Nap-1 from centrosomes See in Reactome R-HSA-380303 ( R-HSA-380259; R-HSA-380284 ) R-HSA-380303 Reaction Name: Dissociation of Phospho-Nlp from the centrosome See in Reactome R-HSA-380311 ( R-HSA-380270 ) R-HSA-380311 Reaction Name: Recruitment of Plk1 to centrosomes See in Reactome R-HSA-380316 ( R-HSA-380320 ) R-HSA-380316 Reaction Name: Association of NuMA with microtubules See in Reactome R-HSA-380455 ( R-HSA-380270 ) R-HSA-380455 Reaction Name: Recruitment of CDK11p58 to the centrosomes See in Reactome R-HSA-380508 ( R-HSA-380320 ) R-HSA-380508 Reaction Name: Translocation of NuMA to the centrosomes See in Reactome R-HSA-381644 ( R-HSA-381676; R-HSA-422356 ) R-HSA-381644 Reaction Name: ER calcium channels open in response to activated PKA See in Reactome R-HSA-381707 ( R-HSA-381676; R-HSA-422356 ) R-HSA-381707 Reaction Name: PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP See in Reactome R-HSA-381713 ( R-HSA-381676; R-HSA-422356 ) R-HSA-381713 Reaction Name: Potassium voltage-gated channels close in reponse to PKA See in Reactome R-HSA-432232 ( R-HSA-432040 ) R-HSA-432232 Reaction Name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) See in Reactome R-HSA-5218854 ( R-HSA-4420097 ) R-HSA-5218854 Reaction Name: p-Y420-FYN is phosphorylated on S21 See in Reactome R-HSA-5610717 ( R-HSA-5610783; R-HSA-5610787 ) R-HSA-5610717 Reaction Name: PKA phosphorylates GLI2 See in Reactome R-HSA-5610720 ( R-HSA-5610785; R-HSA-5610787 ) R-HSA-5610720 Reaction Name: PKA phosphorylates GLI3 See in Reactome R-HSA-5610741 ( R-HSA-5610780; R-HSA-5610787 ) R-HSA-5610741 Reaction Name: PKA phosphorylates GLI1 See in Reactome R-HSA-5610749 ( R-HSA-5610787 ) R-HSA-5610749 Reaction Name: cAMP dissociates PKA, promoting GLI processing See in Reactome R-HSA-5617179 ( R-HSA-5578775 ) R-HSA-5617179 Reaction Name: PRKACA phosphorylates TNNI3 See in Reactome R-HSA-5617182 ( R-HSA-5578775 ) R-HSA-5617182 Reaction Name: PRKACA phosphorylates PLN See in Reactome R-HSA-5617816 ( R-HSA-5620912 ) R-HSA-5617816 Reaction Name: RAB3IP stimulates nucleotide exchange on RAB8A See in Reactome R-HSA-5624473 ( R-HSA-5621575 ) R-HSA-5624473 Reaction Name: Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit See in Reactome R-HSA-5626220 ( R-HSA-5620912 ) R-HSA-5626220 Reaction Name: C2CD3 binds the mother centriole See in Reactome R-HSA-5626223 ( R-HSA-5620912 ) R-HSA-5626223 Reaction Name: C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole See in Reactome R-HSA-5626227 ( R-HSA-5620912 ) R-HSA-5626227 Reaction Name: CP110 and CEP97 dissociate from the centriole See in Reactome R-HSA-5626228 ( R-HSA-5620912 ) R-HSA-5626228 Reaction Name: The distal appendage proteins recruit TTBK2 See in Reactome R-HSA-5626681 ( R-HSA-5620912 ) R-HSA-5626681 Reaction Name: Recruitment of transition zone proteins See in Reactome R-HSA-5626699 ( R-HSA-5620912 ) R-HSA-5626699 Reaction Name: MARK4 binds ODF2 in the centriole See in Reactome R-HSA-5638009 ( R-HSA-5620912 ) R-HSA-5638009 Reaction Name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body See in Reactome R-HSA-5682101 ( R-HSA-8963896 ) R-HSA-5682101 Reaction Name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer See in Reactome R-HSA-5687088 ( R-HSA-5687128 ) R-HSA-5687088 Reaction Name: PKA phosphorylates MAPKAPK5 See in Reactome R-HSA-8853405 ( R-HSA-8854518 ) R-HSA-8853405 Reaction Name: TPX2 binds AURKA at centrosomes See in Reactome R-HSA-8853419 ( R-HSA-8854518 ) R-HSA-8853419 Reaction Name: TPX2 promotes AURKA autophosphorylation See in Reactome R-HSA-8854908 ( R-HSA-8853659 ) R-HSA-8854908 Reaction Name: PKA phosphorylates RET:GDNF:GFRA dimer See in Reactome R-HSA-8951727 ( R-HSA-111931; R-HSA-163615; R-HSA-180024; R-HSA-432040; R-HSA-442720 ) R-HSA-8951727 Reaction Name: cAMP binds PKA tetramer See in Reactome R-HSA-8986937 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-8986937 Reaction Name: MECP2 is phosphorylated at T308 See in Reactome R-HSA-8986939 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-8986939 Reaction Name: MECP2 binds the NCoR/SMRT complex See in Reactome R-HSA-9010641 ( R-HSA-9010642 ) R-HSA-9010641 Reaction Name: AKAP5 recruits PKA to ROBO2 See in Reactome R-HSA-913451 ( R-HSA-512988 ) R-HSA-913451 Reaction Name: IL3RB is phosphorylated on Ser-585 See in Reactome R-HSA-913996 ( R-HSA-392517 ) R-HSA-913996 Reaction Name: PKA/PKG phosphorylate Rap1GAP2 See in Reactome R-HSA-992708 ( R-HSA-983231 ) R-HSA-992708 Reaction Name: Dual-specific AKAPs bind type I and II PKA regulatory subunits See in Reactome
MONDO:0016996	AURKB	Q96GD4	2.7.11.1	R-HSA-5663220 R-HSA-5663220 Reactome Name: RHO GTPases Activate Formins See in Reactome R-HSA-2500257 R-HSA-2500257 Reactome Name: Resolution of Sister Chromatid Cohesion See in Reactome R-HSA-2467813 R-HSA-2467813 Reactome Name: Separation of Sister Chromatids See in Reactome R-HSA-6804756 R-HSA-6804756 Reactome Name: Regulation of TP53 Activity through Phosphorylation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-4615885 R-HSA-4615885 Reactome Name: SUMOylation of DNA replication proteins See in Reactome R-HSA-9648025 R-HSA-9648025 Reactome Name: EML4 and NUDC in mitotic spindle formation See in Reactome R-HSA-174178 R-HSA-174178 Reactome Name: APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 See in Reactome R-HSA-141444 R-HSA-141444 Reactome Name: Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal See in Reactome R-HSA-68877 R-HSA-68877 Reactome Name: Mitotic Prometaphase See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-174143 R-HSA-174143 Reactome Name: APC/C-mediated degradation of cell cycle proteins See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-69620 R-HSA-69620 Reactome Name: Cell Cycle Checkpoints See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-141424 R-HSA-141424 Reactome Name: Amplification of signal from the kinetochores See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-453276 R-HSA-453276 Reactome Name: Regulation of mitotic cell cycle See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-195258 R-HSA-195258 Reactome Name: RHO GTPase Effectors See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-69618 R-HSA-69618 Reactome Name: Mitotic Spindle Checkpoint See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Cell Cycle Gene expression (Transcription) Metabolism of proteins Signal Transduction	R-HSA-141409 ( R-HSA-141444 ) R-HSA-141409 Reaction Name: Mad1 binds kinetochore See in Reactome R-HSA-141422 ( R-HSA-141444 ) R-HSA-141422 Reaction Name: MAD2 converted to an inhibitory state via interaction with Mad1 See in Reactome R-HSA-141431 ( R-HSA-141444 ) R-HSA-141431 Reaction Name: MAD2 associates with the Mad1 kinetochore complex See in Reactome R-HSA-141439 ( R-HSA-141444 ) R-HSA-141439 Reaction Name: Release of activated MAD2 from kinetochores See in Reactome R-HSA-1638803 ( R-HSA-2500257; R-HSA-68877 ) R-HSA-1638803 Reaction Name: Phosphorylation of cohesin by PLK1 at centromeres See in Reactome R-HSA-1638821 ( R-HSA-2500257; R-HSA-68877 ) R-HSA-1638821 Reaction Name: PP2A-B56 dephosphorylates centromeric cohesin See in Reactome R-HSA-174088 ( R-HSA-174178 ) R-HSA-174088 Reaction Name: Association of cell cycle proteins with the APC/C:Cdh1 complex See in Reactome R-HSA-174105 ( R-HSA-174178 ) R-HSA-174105 Reaction Name: Degradation of multiubiquitinated cell cycle proteins See in Reactome R-HSA-174195 ( R-HSA-174178 ) R-HSA-174195 Reaction Name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex See in Reactome R-HSA-2467809 ( R-HSA-2467813 ) R-HSA-2467809 Reaction Name: ESPL1 (Separase) cleaves centromeric cohesin See in Reactome R-HSA-2467811 ( R-HSA-2467813 ) R-HSA-2467811 Reaction Name: Separation of sister chromatids See in Reactome R-HSA-2468287 ( R-HSA-2500257; R-HSA-68877 ) R-HSA-2468287 Reaction Name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres See in Reactome R-HSA-2484822 ( R-HSA-2500257; R-HSA-68877 ) R-HSA-2484822 Reaction Name: Kinetochore assembly See in Reactome R-HSA-375302 ( R-HSA-68877 ) R-HSA-375302 Reaction Name: Kinetochore capture of astral microtubules See in Reactome R-HSA-4655355 ( R-HSA-4615885 ) R-HSA-4655355 Reaction Name: RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) See in Reactome R-HSA-5666129 ( R-HSA-5663220 ) R-HSA-5666129 Reaction Name: CDC42:GTP recruits DIAPH2-2 to kinetochores See in Reactome R-HSA-5666160 ( R-HSA-5663220 ) R-HSA-5666160 Reaction Name: AURKB phosphorylates DIAPH2-2 at kinetochores See in Reactome R-HSA-5666169 ( R-HSA-5663220 ) R-HSA-5666169 Reaction Name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 See in Reactome R-HSA-6805122 ( R-HSA-6804756 ) R-HSA-6805122 Reaction Name: AURKB binds TP53 See in Reactome R-HSA-6805126 ( R-HSA-6804756 ) R-HSA-6805126 Reaction Name: AURKB phosphorylates TP53 See in Reactome R-HSA-9023132 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9023132 Reaction Name: AURKB phosphorylates MECP2 at S423 See in Reactome R-HSA-9648114 ( R-HSA-68877; R-HSA-9648025 ) R-HSA-9648114 Reaction Name: EML4 recruits NUDC to mitotic spindle See in Reactome
MONDO:0018663	LBR	Q14739	1.3.1.70	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-2995383 R-HSA-2995383 Reactome Name: Initiation of Nuclear Envelope (NE) Reformation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-2995410 R-HSA-2995410 Reactome Name: Nuclear Envelope (NE) Reassembly See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Cell Cycle Signal Transduction	R-HSA-194674 ( R-HSA-191273 ) R-HSA-194674 Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] See in Reactome R-HSA-9013004 ( R-HSA-8980692 ) R-HSA-9013004 Reaction Name: RHOA binds effectors at the ER membrane See in Reactome R-HSA-9013438 ( R-HSA-9013405 ) R-HSA-9013438 Reaction Name: RHOD binds effectors at the endosome membrane See in Reactome R-HSA-9014467 ( R-HSA-9013408 ) R-HSA-9014467 Reaction Name: RHOG binds effectors at the ER membrane See in Reactome R-HSA-9018594 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9018594 Reaction Name: MECP2 binds LBR See in Reactome R-HSA-9624798 ( R-HSA-2995383 ) R-HSA-9624798 Reaction Name: LBR binds KPNB1 See in Reactome R-HSA-9624800 ( R-HSA-2995383 ) R-HSA-9624800 Reaction Name: CDK1 phosphorylates LBR See in Reactome R-HSA-9691174 ( R-HSA-9013149 ) R-HSA-9691174 Reaction Name: RAC1 binds effectors at the ER membrane See in Reactome R-HSA-9692809 ( R-HSA-9013148 ) R-HSA-9692809 Reaction Name: CDC42 binds effectors at the ER membrane See in Reactome R-HSA-9714361 ( R-HSA-9013106 ) R-HSA-9714361 Reaction Name: RHOC activates endoplasmic reticulum effectors See in Reactome R-HSA-9714481 ( R-HSA-9013404 ) R-HSA-9714481 Reaction Name: RAC2 binds effectors at the ER membrane See in Reactome R-HSA-9714691 ( R-HSA-9013423 ) R-HSA-9714691 Reaction Name: RAC3 binds ER effectors See in Reactome
MONDO:0018770	LBR	Q14739	1.3.1.70	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-2995383 R-HSA-2995383 Reactome Name: Initiation of Nuclear Envelope (NE) Reformation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-2995410 R-HSA-2995410 Reactome Name: Nuclear Envelope (NE) Reassembly See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Cell Cycle Signal Transduction	R-HSA-194674 ( R-HSA-191273 ) R-HSA-194674 Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] See in Reactome R-HSA-9013004 ( R-HSA-8980692 ) R-HSA-9013004 Reaction Name: RHOA binds effectors at the ER membrane See in Reactome R-HSA-9013438 ( R-HSA-9013405 ) R-HSA-9013438 Reaction Name: RHOD binds effectors at the endosome membrane See in Reactome R-HSA-9014467 ( R-HSA-9013408 ) R-HSA-9014467 Reaction Name: RHOG binds effectors at the ER membrane See in Reactome R-HSA-9018594 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9018594 Reaction Name: MECP2 binds LBR See in Reactome R-HSA-9624798 ( R-HSA-2995383 ) R-HSA-9624798 Reaction Name: LBR binds KPNB1 See in Reactome R-HSA-9624800 ( R-HSA-2995383 ) R-HSA-9624800 Reaction Name: CDK1 phosphorylates LBR See in Reactome R-HSA-9691174 ( R-HSA-9013149 ) R-HSA-9691174 Reaction Name: RAC1 binds effectors at the ER membrane See in Reactome R-HSA-9692809 ( R-HSA-9013148 ) R-HSA-9692809 Reaction Name: CDC42 binds effectors at the ER membrane See in Reactome R-HSA-9714361 ( R-HSA-9013106 ) R-HSA-9714361 Reaction Name: RHOC activates endoplasmic reticulum effectors See in Reactome R-HSA-9714481 ( R-HSA-9013404 ) R-HSA-9714481 Reaction Name: RAC2 binds effectors at the ER membrane See in Reactome R-HSA-9714691 ( R-HSA-9013423 ) R-HSA-9714691 Reaction Name: RAC3 binds ER effectors See in Reactome
MONDO:0030876	PRKACA	P17612	2.7.11.11	R-HSA-442720 R-HSA-442720 Reactome Name: CREB1 phosphorylation through the activation of Adenylate Cyclase See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-381676 R-HSA-381676 Reactome Name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion See in Reactome R-HSA-380259 R-HSA-380259 Reactome Name: Loss of Nlp from mitotic centrosomes See in Reactome R-HSA-983231 R-HSA-983231 Reactome Name: Factors involved in megakaryocyte development and platelet production See in Reactome R-HSA-432040 R-HSA-432040 Reactome Name: Vasopressin regulates renal water homeostasis via Aquaporins See in Reactome R-HSA-380270 R-HSA-380270 Reactome Name: Recruitment of mitotic centrosome proteins and complexes See in Reactome R-HSA-5610783 R-HSA-5610783 Reactome Name: Degradation of GLI2 by the proteasome See in Reactome R-HSA-111931 R-HSA-111931 Reactome Name: PKA-mediated phosphorylation of CREB See in Reactome R-HSA-180024 R-HSA-180024 Reactome Name: DARPP-32 events See in Reactome R-HSA-5610787 R-HSA-5610787 Reactome Name: Hedgehog 'off' state See in Reactome R-HSA-163615 R-HSA-163615 Reactome Name: PKA activation See in Reactome R-HSA-5610785 R-HSA-5610785 Reactome Name: GLI3 is processed to GLI3R by the proteasome See in Reactome R-HSA-164378 R-HSA-164378 Reactome Name: PKA activation in glucagon signalling See in Reactome R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-8853659 R-HSA-8853659 Reactome Name: RET signaling See in Reactome R-HSA-9010642 R-HSA-9010642 Reactome Name: ROBO receptors bind AKAP5 See in Reactome R-HSA-8854518 R-HSA-8854518 Reactome Name: AURKA Activation by TPX2 See in Reactome R-HSA-4420097 R-HSA-4420097 Reactome Name: VEGFA-VEGFR2 Pathway See in Reactome R-HSA-380284 R-HSA-380284 Reactome Name: Loss of proteins required for interphase microtubule organization from the centrosome See in Reactome R-HSA-5687128 R-HSA-5687128 Reactome Name: MAPK6/MAPK4 signaling See in Reactome R-HSA-163560 R-HSA-163560 Reactome Name: Triglyceride catabolism See in Reactome R-HSA-5610780 R-HSA-5610780 Reactome Name: Degradation of GLI1 by the proteasome See in Reactome R-HSA-5620912 R-HSA-5620912 Reactome Name: Anchoring of the basal body to the plasma membrane See in Reactome R-HSA-512988 R-HSA-512988 Reactome Name: Interleukin-3, Interleukin-5 and GM-CSF signaling See in Reactome R-HSA-8963896 R-HSA-8963896 Reactome Name: HDL assembly See in Reactome R-HSA-392517 R-HSA-392517 Reactome Name: Rap1 signalling See in Reactome R-HSA-163358 R-HSA-163358 Reactome Name: PKA-mediated phosphorylation of key metabolic factors See in Reactome R-HSA-422356 R-HSA-422356 Reactome Name: Regulation of insulin secretion See in Reactome R-HSA-2565942 R-HSA-2565942 Reactome Name: Regulation of PLK1 Activity at G2/M Transition See in Reactome R-HSA-380320 R-HSA-380320 Reactome Name: Recruitment of NuMA to mitotic centrosomes See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9634600 R-HSA-9634600 Reactome Name: Regulation of glycolysis by fructose 2,6-bisphosphate metabolism See in Reactome	R-HSA-376176 R-HSA-376176 Reactome Name: Signaling by ROBO receptors See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-5358351 R-HSA-5358351 Reactome Name: Signaling by Hedgehog See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-5617833 R-HSA-5617833 Reactome Name: Cilium Assembly See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-163359 R-HSA-163359 Reactome Name: Glucagon signaling in metabolic regulation See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-1852241 R-HSA-1852241 Reactome Name: Organelle biogenesis and maintenance See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-380287 R-HSA-380287 Reactome Name: Centrosome maturation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-445717 R-HSA-445717 Reactome Name: Aquaporin-mediated transport See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome R-HSA-8963898 R-HSA-8963898 Reactome Name: Plasma lipoprotein assembly See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-68877 R-HSA-68877 Reactome Name: Mitotic Prometaphase See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Muscle contraction Immune System Transport of small molecules Metabolism Cell Cycle Developmental Biology Gene expression (Transcription) Organelle biogenesis and maintenance Neuronal System Hemostasis Signal Transduction	R-HSA-111919 ( R-HSA-111931; R-HSA-442720 ) R-HSA-111919 Reaction Name: PKA phosphorylates CREB1 See in Reactome R-HSA-111924 ( R-HSA-111931; R-HSA-442720 ) R-HSA-111924 Reaction Name: PKA catalytic subunit translocates to the nucleus See in Reactome R-HSA-111925 ( R-HSA-111931; R-HSA-163615; R-HSA-164378; R-HSA-180024; R-HSA-432040; R-HSA-442720 ) R-HSA-111925 Reaction Name: cAMP induces dissociation of inactive PKA tetramers See in Reactome R-HSA-163416 ( R-HSA-163560 ) R-HSA-163416 Reaction Name: hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP See in Reactome R-HSA-163418 ( R-HSA-163560 ) R-HSA-163418 Reaction Name: perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP See in Reactome R-HSA-163672 ( R-HSA-163358 ) R-HSA-163672 Reaction Name: Phosphorylation of ChREBP at Thr(666) by PKA See in Reactome R-HSA-163676 ( R-HSA-163358 ) R-HSA-163676 Reaction Name: Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA See in Reactome R-HSA-163773 ( R-HSA-163358; R-HSA-9634600 ) R-HSA-163773 Reaction Name: Phosphorylation of PF2K-Pase by PKA catalytic subunit See in Reactome R-HSA-177275 ( R-HSA-180024 ) R-HSA-177275 Reaction Name: PKA phosphorylates DARPP-32 on Thr34 See in Reactome R-HSA-177284 ( R-HSA-180024 ) R-HSA-177284 Reaction Name: PKA phosphorylates PDE4B See in Reactome R-HSA-180073 ( R-HSA-180024 ) R-HSA-180073 Reaction Name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function See in Reactome R-HSA-2574840 ( R-HSA-2565942 ) R-HSA-2574840 Reaction Name: AJUBA facilitates AURKA autophosphorylation See in Reactome R-HSA-2574845 ( R-HSA-2565942 ) R-HSA-2574845 Reaction Name: AJUBA binds centrosome-associated AURKA See in Reactome R-HSA-265682 ( R-HSA-422356 ) R-HSA-265682 Reaction Name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel See in Reactome R-HSA-3000310 ( R-HSA-2565942 ) R-HSA-3000310 Reaction Name: AURKA phosphorylates PLK1 See in Reactome R-HSA-3000319 ( R-HSA-2565942 ) R-HSA-3000319 Reaction Name: BORA binds PLK1 and AURKA See in Reactome R-HSA-380272 ( R-HSA-380259; R-HSA-380284 ) R-HSA-380272 Reaction Name: Plk1-mediated phosphorylation of Nlp See in Reactome R-HSA-380283 ( R-HSA-380270 ) R-HSA-380283 Reaction Name: Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome See in Reactome R-HSA-380294 ( R-HSA-380284 ) R-HSA-380294 Reaction Name: Loss of C-Nap-1 from centrosomes See in Reactome R-HSA-380303 ( R-HSA-380259; R-HSA-380284 ) R-HSA-380303 Reaction Name: Dissociation of Phospho-Nlp from the centrosome See in Reactome R-HSA-380311 ( R-HSA-380270 ) R-HSA-380311 Reaction Name: Recruitment of Plk1 to centrosomes See in Reactome R-HSA-380316 ( R-HSA-380320 ) R-HSA-380316 Reaction Name: Association of NuMA with microtubules See in Reactome R-HSA-380455 ( R-HSA-380270 ) R-HSA-380455 Reaction Name: Recruitment of CDK11p58 to the centrosomes See in Reactome R-HSA-380508 ( R-HSA-380320 ) R-HSA-380508 Reaction Name: Translocation of NuMA to the centrosomes See in Reactome R-HSA-381644 ( R-HSA-381676; R-HSA-422356 ) R-HSA-381644 Reaction Name: ER calcium channels open in response to activated PKA See in Reactome R-HSA-381707 ( R-HSA-381676; R-HSA-422356 ) R-HSA-381707 Reaction Name: PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP See in Reactome R-HSA-381713 ( R-HSA-381676; R-HSA-422356 ) R-HSA-381713 Reaction Name: Potassium voltage-gated channels close in reponse to PKA See in Reactome R-HSA-432232 ( R-HSA-432040 ) R-HSA-432232 Reaction Name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) See in Reactome R-HSA-5218854 ( R-HSA-4420097 ) R-HSA-5218854 Reaction Name: p-Y420-FYN is phosphorylated on S21 See in Reactome R-HSA-5610717 ( R-HSA-5610783; R-HSA-5610787 ) R-HSA-5610717 Reaction Name: PKA phosphorylates GLI2 See in Reactome R-HSA-5610720 ( R-HSA-5610785; R-HSA-5610787 ) R-HSA-5610720 Reaction Name: PKA phosphorylates GLI3 See in Reactome R-HSA-5610741 ( R-HSA-5610780; R-HSA-5610787 ) R-HSA-5610741 Reaction Name: PKA phosphorylates GLI1 See in Reactome R-HSA-5610749 ( R-HSA-5610787 ) R-HSA-5610749 Reaction Name: cAMP dissociates PKA, promoting GLI processing See in Reactome R-HSA-5617179 ( R-HSA-5578775 ) R-HSA-5617179 Reaction Name: PRKACA phosphorylates TNNI3 See in Reactome R-HSA-5617182 ( R-HSA-5578775 ) R-HSA-5617182 Reaction Name: PRKACA phosphorylates PLN See in Reactome R-HSA-5617816 ( R-HSA-5620912 ) R-HSA-5617816 Reaction Name: RAB3IP stimulates nucleotide exchange on RAB8A See in Reactome R-HSA-5624473 ( R-HSA-5621575 ) R-HSA-5624473 Reaction Name: Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit See in Reactome R-HSA-5626220 ( R-HSA-5620912 ) R-HSA-5626220 Reaction Name: C2CD3 binds the mother centriole See in Reactome R-HSA-5626223 ( R-HSA-5620912 ) R-HSA-5626223 Reaction Name: C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole See in Reactome R-HSA-5626227 ( R-HSA-5620912 ) R-HSA-5626227 Reaction Name: CP110 and CEP97 dissociate from the centriole See in Reactome R-HSA-5626228 ( R-HSA-5620912 ) R-HSA-5626228 Reaction Name: The distal appendage proteins recruit TTBK2 See in Reactome R-HSA-5626681 ( R-HSA-5620912 ) R-HSA-5626681 Reaction Name: Recruitment of transition zone proteins See in Reactome R-HSA-5626699 ( R-HSA-5620912 ) R-HSA-5626699 Reaction Name: MARK4 binds ODF2 in the centriole See in Reactome R-HSA-5638009 ( R-HSA-5620912 ) R-HSA-5638009 Reaction Name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body See in Reactome R-HSA-5682101 ( R-HSA-8963896 ) R-HSA-5682101 Reaction Name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer See in Reactome R-HSA-5687088 ( R-HSA-5687128 ) R-HSA-5687088 Reaction Name: PKA phosphorylates MAPKAPK5 See in Reactome R-HSA-8853405 ( R-HSA-8854518 ) R-HSA-8853405 Reaction Name: TPX2 binds AURKA at centrosomes See in Reactome R-HSA-8853419 ( R-HSA-8854518 ) R-HSA-8853419 Reaction Name: TPX2 promotes AURKA autophosphorylation See in Reactome R-HSA-8854908 ( R-HSA-8853659 ) R-HSA-8854908 Reaction Name: PKA phosphorylates RET:GDNF:GFRA dimer See in Reactome R-HSA-8951727 ( R-HSA-111931; R-HSA-163615; R-HSA-180024; R-HSA-432040; R-HSA-442720 ) R-HSA-8951727 Reaction Name: cAMP binds PKA tetramer See in Reactome R-HSA-8986937 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-8986937 Reaction Name: MECP2 is phosphorylated at T308 See in Reactome R-HSA-8986939 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-8986939 Reaction Name: MECP2 binds the NCoR/SMRT complex See in Reactome R-HSA-9010641 ( R-HSA-9010642 ) R-HSA-9010641 Reaction Name: AKAP5 recruits PKA to ROBO2 See in Reactome R-HSA-913451 ( R-HSA-512988 ) R-HSA-913451 Reaction Name: IL3RB is phosphorylated on Ser-585 See in Reactome R-HSA-913996 ( R-HSA-392517 ) R-HSA-913996 Reaction Name: PKA/PKG phosphorylate Rap1GAP2 See in Reactome R-HSA-992708 ( R-HSA-983231 ) R-HSA-992708 Reaction Name: Dual-specific AKAPs bind type I and II PKA regulatory subunits See in Reactome
MONDO:0030897	AGO2	Q9UKV8	3.1.26.n2	R-HSA-8934593 R-HSA-8934593 Reactome Name: Regulation of RUNX1 Expression and Activity See in Reactome R-HSA-426486 R-HSA-426486 Reactome Name: Small interfering RNA (siRNA) biogenesis See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8943723 R-HSA-8943723 Reactome Name: Regulation of PTEN mRNA translation See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8948700 R-HSA-8948700 Reactome Name: Competing endogenous RNAs (ceRNAs) regulate PTEN translation See in Reactome R-HSA-203927 R-HSA-203927 Reactome Name: MicroRNA (miRNA) biogenesis See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-5578749 R-HSA-5578749 Reactome Name: Transcriptional regulation by small RNAs See in Reactome R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome R-HSA-426496 R-HSA-426496 Reactome Name: Post-transcriptional silencing by small RNAs See in Reactome R-HSA-5687128 R-HSA-5687128 Reactome Name: MAPK6/MAPK4 signaling See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-1257604 R-HSA-1257604 Reactome Name: PIP3 activates AKT signaling See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-6807070 R-HSA-6807070 Reactome Name: PTEN Regulation See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Signal Transduction	R-HSA-1606561 ( R-HSA-1912408 ) R-HSA-1606561 Reaction Name: MIR449 microRNAs bind 3'UTR of NOTCH1 mRNA See in Reactome R-HSA-1606682 ( R-HSA-1912408 ) R-HSA-1606682 Reaction Name: MIR34 microRNAs bind 3'UTR of NOTCH1 mRNA See in Reactome R-HSA-1912362 ( R-HSA-1912408 ) R-HSA-1912362 Reaction Name: MIR150 microRNA binds 3'UTR of NOTCH3 mRNA See in Reactome R-HSA-1912363 ( R-HSA-1912408 ) R-HSA-1912363 Reaction Name: MIR200B/C microRNAs bind NOTCH1 mRNA See in Reactome R-HSA-1912364 ( R-HSA-1912408 ) R-HSA-1912364 Reaction Name: MIR181C microRNA binds 3'UTR of NOTCH4 mRNA See in Reactome R-HSA-1912366 ( R-HSA-1912408 ) R-HSA-1912366 Reaction Name: MIR206 microRNA binds 3'UTR of NOTCH3 mRNA See in Reactome R-HSA-1912367 ( R-HSA-1912408 ) R-HSA-1912367 Reaction Name: MIR34 microRNAs bind 3'UTR of NOTCH2 mRNA See in Reactome R-HSA-1912368 ( R-HSA-1912408 ) R-HSA-1912368 Reaction Name: MIR302A microRNA binds 3'UTR of NOTCH4 mRNA See in Reactome R-HSA-1912406 ( R-HSA-1912408 ) R-HSA-1912406 Reaction Name: p53 positively regulates transcription of MIR34 microRNAs See in Reactome R-HSA-1912409 ( R-HSA-1912408 ) R-HSA-1912409 Reaction Name: NOTCH3 mRNA translation controlled by miRNAs See in Reactome R-HSA-1912410 ( R-HSA-1912408 ) R-HSA-1912410 Reaction Name: NOTCH4 mRNA translation controlled by miRNAs See in Reactome R-HSA-1912412 ( R-HSA-1912408 ) R-HSA-1912412 Reaction Name: NOTCH1 mRNA translation controlled by miRNAs See in Reactome R-HSA-1912413 ( R-HSA-1912408 ) R-HSA-1912413 Reaction Name: NOTCH2 mRNA translation controlled by miRNAs See in Reactome R-HSA-203862 ( R-HSA-203927 ) R-HSA-203862 Reaction Name: Dicer cleaves pre-miRNA to yield duplex miRNA See in Reactome R-HSA-2106614 ( R-HSA-203927 ) R-HSA-2106614 Reaction Name: Duplex miRNA is loaded into Argonaute See in Reactome R-HSA-2106615 ( R-HSA-426486 ) R-HSA-2106615 Reaction Name: Removal of siRNA passenger strand See in Reactome R-HSA-2106625 ( R-HSA-426486 ) R-HSA-2106625 Reaction Name: Duplex siRNA is loaded into Argonaute See in Reactome R-HSA-210805 ( R-HSA-203927 ) R-HSA-210805 Reaction Name: Removal of miRNA passenger strand See in Reactome R-HSA-2318752 ( R-HSA-5628897; R-HSA-8943723 ) R-HSA-2318752 Reaction Name: miR-26A microRNAs bind PTEN mRNA See in Reactome R-HSA-2321904 ( R-HSA-5628897 ) R-HSA-2321904 Reaction Name: PTEN mRNA translation negatively regulated by microRNAs See in Reactome R-HSA-426464 ( R-HSA-426486 ) R-HSA-426464 Reaction Name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA See in Reactome R-HSA-426489 ( R-HSA-426496 ) R-HSA-426489 Reaction Name: RISC binds inexactly matching target RNAs See in Reactome R-HSA-426520 ( R-HSA-426496 ) R-HSA-426520 Reaction Name: Endonucleolytic RISC hydrolyzes target RNAs See in Reactome R-HSA-4518575 ( R-HSA-4086398 ) R-HSA-4518575 Reaction Name: miR-92b binds 3'UTR of NLK mRNA See in Reactome R-HSA-4518585 ( R-HSA-4086398 ) R-HSA-4518585 Reaction Name: NLK mRNA translation controlled by miR-92b See in Reactome R-HSA-5578712 ( R-HSA-5578749 ) R-HSA-5578712 Reaction Name: Importin-8 binds AGO2:miRNA See in Reactome R-HSA-5578742 ( R-HSA-5578749 ) R-HSA-5578742 Reaction Name: AGO1,2:small RNA complexes interact with chromatin See in Reactome R-HSA-5578744 ( R-HSA-5578749 ) R-HSA-5578744 Reaction Name: Importin-8 imports AGO2:miRNA into the nucleus See in Reactome R-HSA-5578965 ( R-HSA-5578749 ) R-HSA-5578965 Reaction Name: TNRC6A binds AGO2:miRNA See in Reactome R-HSA-5578966 ( R-HSA-5578749 ) R-HSA-5578966 Reaction Name: TNRC6A:AGO2:miRNA is transported into the nucleus See in Reactome R-HSA-5687103 ( R-HSA-5687128 ) R-HSA-5687103 Reaction Name: FOXO3 regulates MIR34B,C expression See in Reactome R-HSA-5687113 ( R-HSA-5687128 ) R-HSA-5687113 Reaction Name: MYC mRNA translation is negatively regulated by miR-34B and C See in Reactome R-HSA-8935785 ( R-HSA-8934593 ) R-HSA-8935785 Reaction Name: RUNX1 mRNA translation is inhibited by miR-17, miR-18a, miR-20a, miR-27a, miR-106a, miR-215, miR-302b, miR-378 and miR-675 See in Reactome R-HSA-8935864 ( R-HSA-8934593 ) R-HSA-8935864 Reaction Name: miR-302b binds RUNX1 mRNA See in Reactome R-HSA-8935930 ( R-HSA-8934593 ) R-HSA-8935930 Reaction Name: miR-18a binds RUNX1 mRNA See in Reactome R-HSA-8936058 ( R-HSA-8934593 ) R-HSA-8936058 Reaction Name: miR-675 binds RUNX1 mRNA See in Reactome R-HSA-8936068 ( R-HSA-8934593 ) R-HSA-8936068 Reaction Name: H19 is cleaved to produce miR-675 See in Reactome R-HSA-8939129 ( R-HSA-8934593 ) R-HSA-8939129 Reaction Name: miR-215 binds RUNX1 mRNA See in Reactome R-HSA-8944483 ( R-HSA-8943723 ) R-HSA-8944483 Reaction Name: miR-17 microRNA binds PTEN mRNA See in Reactome R-HSA-8944497 ( R-HSA-8943723 ) R-HSA-8944497 Reaction Name: PTEN mRNA translation is negatively regulated by microRNAs See in Reactome R-HSA-8944522 ( R-HSA-8943723 ) R-HSA-8944522 Reaction Name: miR-19a microRNA binds PTEN mRNA See in Reactome R-HSA-8944538 ( R-HSA-8943723 ) R-HSA-8944538 Reaction Name: miR-22 microRNA binds PTEN mRNA See in Reactome R-HSA-8944569 ( R-HSA-8943723 ) R-HSA-8944569 Reaction Name: miR-25 microRNA binds PTEN mRNA See in Reactome R-HSA-8944599 ( R-HSA-8943723 ) R-HSA-8944599 Reaction Name: miR-93 microRNA binds PTEN mRNA See in Reactome R-HSA-8944632 ( R-HSA-8943723 ) R-HSA-8944632 Reaction Name: miR-106 microRNAs bind PTEN mRNA See in Reactome R-HSA-8944684 ( R-HSA-8943723 ) R-HSA-8944684 Reaction Name: miR-205 microRNA binds PTEN mRNA See in Reactome R-HSA-8945709 ( R-HSA-8943723 ) R-HSA-8945709 Reaction Name: miR-20 microRNAs bind PTEN mRNA See in Reactome R-HSA-8948524 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948524 Reaction Name: PTENP1 mRNA binds miR-19b RISC See in Reactome R-HSA-8948536 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948536 Reaction Name: PTENP1 mRNA binds miR-20 RISC See in Reactome R-HSA-8948569 ( R-HSA-8943723 ) R-HSA-8948569 Reaction Name: miR-19b microRNA binds PTEN mRNA See in Reactome R-HSA-8948582 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948582 Reaction Name: miR-17 microRNA binds VAPA mRNA See in Reactome R-HSA-8948583 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948583 Reaction Name: miR-17 microRNA binds CNOT6L mRNA See in Reactome R-HSA-8948594 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948594 Reaction Name: miR-19a microRNA binds VAPA mRNA See in Reactome R-HSA-8948602 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948602 Reaction Name: miR-19a microRNA binds CNOT6L mRNA See in Reactome R-HSA-8948612 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948612 Reaction Name: miR-19b microRNA binds CNOT6L mRNA See in Reactome R-HSA-8948621 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948621 Reaction Name: miR-20 microRNAs bind VAPA mRNA See in Reactome R-HSA-8948623 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948623 Reaction Name: miR-20 microRNAs bind CNOT6L mRNA See in Reactome R-HSA-8948641 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948641 Reaction Name: miR-106 microRNAs bind VAPA mRNA See in Reactome R-HSA-8948651 ( R-HSA-8943723; R-HSA-8948700 ) R-HSA-8948651 Reaction Name: miR-106a,(miR106b) microRNA binds CNOT6L mRNA See in Reactome R-HSA-9011958 ( R-HSA-9018519 ) R-HSA-9011958 Reaction Name: miR-26A and B bind to the 3'UTR of the GREB1 mRNA See in Reactome R-HSA-9011961 ( R-HSA-9018519 ) R-HSA-9011961 Reaction Name: GREB1 translation is negatively regulated by miR-26A and B See in Reactome R-HSA-9012186 ( R-HSA-9018519 ) R-HSA-9012186 Reaction Name: CHD1 translation is negatively regulated by miR-26A and B See in Reactome R-HSA-9012196 ( R-HSA-9018519 ) R-HSA-9012196 Reaction Name: KPNA2 translation is negatively regulated by miR-26A and B See in Reactome R-HSA-9012203 ( R-HSA-9018519 ) R-HSA-9012203 Reaction Name: miR-26A and B bind to the 3'UTR of the CHD11 mRNA See in Reactome R-HSA-9012208 ( R-HSA-9018519 ) R-HSA-9012208 Reaction Name: miR-26A and B bind to the 3'UTR of the KPNA2 mRNA See in Reactome R-HSA-9021182 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9021182 Reaction Name: MECP2 mRNA binds miR-132 RISC See in Reactome R-HSA-9021183 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9021183 Reaction Name: MECP2 mRNA translation is inhibited by miR-132 See in Reactome R-HSA-9023909 ( R-HSA-426486 ) R-HSA-9023909 Reaction Name: C3PO hydrolyzes cleaved passenger strand See in Reactome R-HSA-9023912 ( R-HSA-426486 ) R-HSA-9023912 Reaction Name: AGO2 cleaves passenger strand of duplex siRNA See in Reactome R-HSA-9038545 ( R-HSA-9029569 ) R-HSA-9038545 Reaction Name: miR-613 binds to the 3'UTR of the NR1H3 mRNA See in Reactome R-HSA-9605052 ( R-HSA-9029569 ) R-HSA-9605052 Reaction Name: NR1H3 mRNA is translated See in Reactome R-HSA-9615501 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9615501 Reaction Name: MIR132 gene expression is stimulated by p-S133-CREB1 See in Reactome R-HSA-9615554 ( R-HSA-8986944 ) R-HSA-9615554 Reaction Name: MIR137 gene expression is inhibited by MECP2 and SOX2 See in Reactome R-HSA-9615570 ( R-HSA-8986944 ) R-HSA-9615570 Reaction Name: miR-137 binds PTEN mRNA See in Reactome R-HSA-9615571 ( R-HSA-8986944 ) R-HSA-9615571 Reaction Name: PTEN mRNA translation is inhibited by miR-137 See in Reactome R-HSA-9618392 ( R-HSA-9029569 ) R-HSA-9618392 Reaction Name: miR-26 binds to the 3'UTR of the ARL4C mRNA See in Reactome R-HSA-9618405 ( R-HSA-9029569 ) R-HSA-9618405 Reaction Name: ARL4C mRNA is translated See in Reactome R-HSA-9618479 ( R-HSA-9029569 ) R-HSA-9618479 Reaction Name: ABCA1 mRNA is translated See in Reactome R-HSA-9618486 ( R-HSA-9029569 ) R-HSA-9618486 Reaction Name: miR-26 binds to the 3'UTR of the ABCA1 mRNA See in Reactome R-HSA-9624925 ( R-HSA-9029569 ) R-HSA-9624925 Reaction Name: miR-33 binds to the 3'UTR of the ABCA1 mRNA See in Reactome R-HSA-9657791 ( R-HSA-9029569 ) R-HSA-9657791 Reaction Name: miR-144 binds to the 3'UTR of the ABCA1 mRNA See in Reactome
MONDO:0030919	CAMK2A	Q9UQM7	2.7.11.17	R-HSA-111932 R-HSA-111932 Reactome Name: CaMK IV-mediated phosphorylation of CREB See in Reactome R-HSA-9617324 R-HSA-9617324 Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission See in Reactome R-HSA-5576892 R-HSA-5576892 Reactome Name: Phase 0 - rapid depolarisation See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-399719 R-HSA-399719 Reactome Name: Trafficking of AMPA receptors See in Reactome R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-877300 R-HSA-877300 Reactome Name: Interferon gamma signaling See in Reactome R-HSA-438066 R-HSA-438066 Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation See in Reactome R-HSA-442982 R-HSA-442982 Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-936837 R-HSA-936837 Reactome Name: Ion transport by P-type ATPases See in Reactome R-HSA-9609736 R-HSA-9609736 Reactome Name: Assembly and cell surface presentation of NMDA receptors See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-442742 R-HSA-442742 Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-913531 R-HSA-913531 Reactome Name: Interferon Signaling See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-399721 R-HSA-399721 Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Muscle contraction Immune System Transport of small molecules Gene expression (Transcription) Neuronal System Cellular responses to stimuli Signal Transduction	R-HSA-416320 ( R-HSA-399719 ) R-HSA-416320 Reaction Name: Trafficking of GluR1-containing AMPA receptors See in Reactome R-HSA-427910 ( R-HSA-5578775; R-HSA-936837 ) R-HSA-427910 Reaction Name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen See in Reactome R-HSA-432162 ( R-HSA-438066 ) R-HSA-432162 Reaction Name: Unblocking of GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-432164 ( R-HSA-438066 ) R-HSA-432164 Reaction Name: Ca2+ influx into the post-synaptic cell See in Reactome R-HSA-432172 ( R-HSA-438066 ) R-HSA-432172 Reaction Name: Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor See in Reactome R-HSA-4332356 ( R-HSA-4086398 ) R-HSA-4332356 Reaction Name: CAMK2 binds MAP3K7 See in Reactome R-HSA-4332358 ( R-HSA-4086398 ) R-HSA-4332358 Reaction Name: Dissociation of CaM and CAMK2 autophosphorylation See in Reactome R-HSA-4332359 ( R-HSA-4086398 ) R-HSA-4332359 Reaction Name: Active calmodulin binds CAMK2 See in Reactome R-HSA-4332363 ( R-HSA-4086398 ) R-HSA-4332363 Reaction Name: Autophosphorylation and activation of CAMK2 See in Reactome R-HSA-4332388 ( R-HSA-4086398 ) R-HSA-4332388 Reaction Name: Activation of MAP3K7 in response to WNT See in Reactome R-HSA-438037 ( R-HSA-438066 ) R-HSA-438037 Reaction Name: Membrane depolarization upon activation of Ca impermeable AMPA receptors See in Reactome R-HSA-442725 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-442725 Reaction Name: CaMKII binds activated calmodulin See in Reactome R-HSA-442732 ( R-HSA-442982 ) R-HSA-442732 Reaction Name: NMDA-activated RASGRF1 activates RAS See in Reactome R-HSA-442760 ( R-HSA-442982 ) R-HSA-442760 Reaction Name: Activation of RasGRF See in Reactome R-HSA-445367 ( R-HSA-9620244 ) R-HSA-445367 Reaction Name: CaMKII binds activated NMDA receptor See in Reactome R-HSA-5082387 ( R-HSA-3371571 ) R-HSA-5082387 Reaction Name: Phosphorylation of HSF1 at Ser230 induces transactivation See in Reactome R-HSA-5576895 ( R-HSA-5576892 ) R-HSA-5576895 Reaction Name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-9006992 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9006992 Reaction Name: MECP2 is phosphorylated at S423 See in Reactome R-HSA-909552 ( R-HSA-877300 ) R-HSA-909552 Reaction Name: Phosphorylation of STAT1 at Ser727 See in Reactome R-HSA-9611368 ( R-HSA-9609736 ) R-HSA-9611368 Reaction Name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9614185 ( R-HSA-438066 ) R-HSA-9614185 Reaction Name: Mg2+ binds GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-9617326 ( R-HSA-9617324 ) R-HSA-9617326 Reaction Name: CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 See in Reactome R-HSA-9617583 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-9617583 Reaction Name: CaMKII autophosphorylates See in Reactome R-HSA-9618750 ( R-HSA-9620244 ) R-HSA-9618750 Reaction Name: CaMKII phosphorylates AMPA receptor See in Reactome R-HSA-9619449 ( R-HSA-9617324 ) R-HSA-9619449 Reaction Name: PPM1F dephosphorylates p-T286-CaMKII See in Reactome
MONDO:0030920	CAMK2B	Q13554	2.7.11.17	R-HSA-442729 R-HSA-442729 Reactome Name: CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde See in Reactome R-HSA-111932 R-HSA-111932 Reactome Name: CaMK IV-mediated phosphorylation of CREB See in Reactome R-HSA-9617324 R-HSA-9617324 Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission See in Reactome R-HSA-5576892 R-HSA-5576892 Reactome Name: Phase 0 - rapid depolarisation See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-399719 R-HSA-399719 Reactome Name: Trafficking of AMPA receptors See in Reactome R-HSA-877300 R-HSA-877300 Reactome Name: Interferon gamma signaling See in Reactome R-HSA-438066 R-HSA-438066 Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation See in Reactome R-HSA-442982 R-HSA-442982 Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-936837 R-HSA-936837 Reactome Name: Ion transport by P-type ATPases See in Reactome R-HSA-9609736 R-HSA-9609736 Reactome Name: Assembly and cell surface presentation of NMDA receptors See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-442742 R-HSA-442742 Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-913531 R-HSA-913531 Reactome Name: Interferon Signaling See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-399721 R-HSA-399721 Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Muscle contraction Immune System Transport of small molecules Gene expression (Transcription) Neuronal System Cellular responses to stimuli Signal Transduction	R-HSA-416320 ( R-HSA-399719 ) R-HSA-416320 Reaction Name: Trafficking of GluR1-containing AMPA receptors See in Reactome R-HSA-427910 ( R-HSA-5578775; R-HSA-936837 ) R-HSA-427910 Reaction Name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen See in Reactome R-HSA-432162 ( R-HSA-438066 ) R-HSA-432162 Reaction Name: Unblocking of GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-432164 ( R-HSA-438066 ) R-HSA-432164 Reaction Name: Ca2+ influx into the post-synaptic cell See in Reactome R-HSA-432172 ( R-HSA-438066 ) R-HSA-432172 Reaction Name: Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor See in Reactome R-HSA-438037 ( R-HSA-438066 ) R-HSA-438037 Reaction Name: Membrane depolarization upon activation of Ca impermeable AMPA receptors See in Reactome R-HSA-442725 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-442725 Reaction Name: CaMKII binds activated calmodulin See in Reactome R-HSA-442732 ( R-HSA-442982 ) R-HSA-442732 Reaction Name: NMDA-activated RASGRF1 activates RAS See in Reactome R-HSA-442760 ( R-HSA-442982 ) R-HSA-442760 Reaction Name: Activation of RasGRF See in Reactome R-HSA-444792 ( R-HSA-111932; R-HSA-442729 ) R-HSA-444792 Reaction Name: Calmodulin-bound CaMKII-gamma enters the nucleus See in Reactome R-HSA-445367 ( R-HSA-9620244 ) R-HSA-445367 Reaction Name: CaMKII binds activated NMDA receptor See in Reactome R-HSA-5082387 ( R-HSA-3371571 ) R-HSA-5082387 Reaction Name: Phosphorylation of HSF1 at Ser230 induces transactivation See in Reactome R-HSA-5576895 ( R-HSA-5576892 ) R-HSA-5576895 Reaction Name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-9006992 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9006992 Reaction Name: MECP2 is phosphorylated at S423 See in Reactome R-HSA-909552 ( R-HSA-877300 ) R-HSA-909552 Reaction Name: Phosphorylation of STAT1 at Ser727 See in Reactome R-HSA-9611368 ( R-HSA-9609736 ) R-HSA-9611368 Reaction Name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9614185 ( R-HSA-438066 ) R-HSA-9614185 Reaction Name: Mg2+ binds GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-9617326 ( R-HSA-9617324 ) R-HSA-9617326 Reaction Name: CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 See in Reactome R-HSA-9617583 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-9617583 Reaction Name: CaMKII autophosphorylates See in Reactome R-HSA-9618750 ( R-HSA-9620244 ) R-HSA-9618750 Reaction Name: CaMKII phosphorylates AMPA receptor See in Reactome R-HSA-9619449 ( R-HSA-9617324 ) R-HSA-9619449 Reaction Name: PPM1F dephosphorylates p-T286-CaMKII See in Reactome
MONDO:0032795	CAMK2G	Q13555	2.7.11.17	R-HSA-442729 R-HSA-442729 Reactome Name: CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde See in Reactome R-HSA-111932 R-HSA-111932 Reactome Name: CaMK IV-mediated phosphorylation of CREB See in Reactome R-HSA-9617324 R-HSA-9617324 Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission See in Reactome R-HSA-5576892 R-HSA-5576892 Reactome Name: Phase 0 - rapid depolarisation See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-399719 R-HSA-399719 Reactome Name: Trafficking of AMPA receptors See in Reactome R-HSA-877300 R-HSA-877300 Reactome Name: Interferon gamma signaling See in Reactome R-HSA-438066 R-HSA-438066 Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation See in Reactome R-HSA-442982 R-HSA-442982 Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-936837 R-HSA-936837 Reactome Name: Ion transport by P-type ATPases See in Reactome R-HSA-9609736 R-HSA-9609736 Reactome Name: Assembly and cell surface presentation of NMDA receptors See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-442742 R-HSA-442742 Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-913531 R-HSA-913531 Reactome Name: Interferon Signaling See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-399721 R-HSA-399721 Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Muscle contraction Immune System Transport of small molecules Gene expression (Transcription) Neuronal System Cellular responses to stimuli Signal Transduction	R-HSA-416320 ( R-HSA-399719 ) R-HSA-416320 Reaction Name: Trafficking of GluR1-containing AMPA receptors See in Reactome R-HSA-427910 ( R-HSA-5578775; R-HSA-936837 ) R-HSA-427910 Reaction Name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen See in Reactome R-HSA-432162 ( R-HSA-438066 ) R-HSA-432162 Reaction Name: Unblocking of GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-432164 ( R-HSA-438066 ) R-HSA-432164 Reaction Name: Ca2+ influx into the post-synaptic cell See in Reactome R-HSA-432172 ( R-HSA-438066 ) R-HSA-432172 Reaction Name: Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor See in Reactome R-HSA-438037 ( R-HSA-438066 ) R-HSA-438037 Reaction Name: Membrane depolarization upon activation of Ca impermeable AMPA receptors See in Reactome R-HSA-442725 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-442725 Reaction Name: CaMKII binds activated calmodulin See in Reactome R-HSA-442732 ( R-HSA-442982 ) R-HSA-442732 Reaction Name: NMDA-activated RASGRF1 activates RAS See in Reactome R-HSA-442760 ( R-HSA-442982 ) R-HSA-442760 Reaction Name: Activation of RasGRF See in Reactome R-HSA-444792 ( R-HSA-111932; R-HSA-442729 ) R-HSA-444792 Reaction Name: Calmodulin-bound CaMKII-gamma enters the nucleus See in Reactome R-HSA-445367 ( R-HSA-9620244 ) R-HSA-445367 Reaction Name: CaMKII binds activated NMDA receptor See in Reactome R-HSA-5082387 ( R-HSA-3371571 ) R-HSA-5082387 Reaction Name: Phosphorylation of HSF1 at Ser230 induces transactivation See in Reactome R-HSA-5576895 ( R-HSA-5576892 ) R-HSA-5576895 Reaction Name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-9006992 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9006992 Reaction Name: MECP2 is phosphorylated at S423 See in Reactome R-HSA-909552 ( R-HSA-877300 ) R-HSA-909552 Reaction Name: Phosphorylation of STAT1 at Ser727 See in Reactome R-HSA-9611368 ( R-HSA-9609736 ) R-HSA-9611368 Reaction Name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9614185 ( R-HSA-438066 ) R-HSA-9614185 Reaction Name: Mg2+ binds GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-9617326 ( R-HSA-9617324 ) R-HSA-9617326 Reaction Name: CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 See in Reactome R-HSA-9617583 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-9617583 Reaction Name: CaMKII autophosphorylates See in Reactome R-HSA-9618750 ( R-HSA-9620244 ) R-HSA-9618750 Reaction Name: CaMKII phosphorylates AMPA receptor See in Reactome R-HSA-9618834 ( R-HSA-111932; R-HSA-442729 ) R-HSA-9618834 Reaction Name: Activated calmodulin dissociates from CaMKII-gamma See in Reactome R-HSA-9619449 ( R-HSA-9617324 ) R-HSA-9619449 Reaction Name: PPM1F dephosphorylates p-T286-CaMKII See in Reactome
MONDO:0054861	CAMK2A	Q9UQM7	2.7.11.17	R-HSA-111932 R-HSA-111932 Reactome Name: CaMK IV-mediated phosphorylation of CREB See in Reactome R-HSA-9617324 R-HSA-9617324 Reactome Name: Negative regulation of NMDA receptor-mediated neuronal transmission See in Reactome R-HSA-5576892 R-HSA-5576892 Reactome Name: Phase 0 - rapid depolarisation See in Reactome R-HSA-9620244 R-HSA-9620244 Reactome Name: Long-term potentiation See in Reactome R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-399719 R-HSA-399719 Reactome Name: Trafficking of AMPA receptors See in Reactome R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-877300 R-HSA-877300 Reactome Name: Interferon gamma signaling See in Reactome R-HSA-438066 R-HSA-438066 Reactome Name: Unblocking of NMDA receptors, glutamate binding and activation See in Reactome R-HSA-442982 R-HSA-442982 Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-936837 R-HSA-936837 Reactome Name: Ion transport by P-type ATPases See in Reactome R-HSA-9609736 R-HSA-9609736 Reactome Name: Assembly and cell surface presentation of NMDA receptors See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-442742 R-HSA-442742 Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-913531 R-HSA-913531 Reactome Name: Interferon Signaling See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-399721 R-HSA-399721 Reactome Name: Glutamate binding, activation of AMPA receptors and synaptic plasticity See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Muscle contraction Immune System Transport of small molecules Gene expression (Transcription) Neuronal System Cellular responses to stimuli Signal Transduction	R-HSA-416320 ( R-HSA-399719 ) R-HSA-416320 Reaction Name: Trafficking of GluR1-containing AMPA receptors See in Reactome R-HSA-427910 ( R-HSA-5578775; R-HSA-936837 ) R-HSA-427910 Reaction Name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen See in Reactome R-HSA-432162 ( R-HSA-438066 ) R-HSA-432162 Reaction Name: Unblocking of GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-432164 ( R-HSA-438066 ) R-HSA-432164 Reaction Name: Ca2+ influx into the post-synaptic cell See in Reactome R-HSA-432172 ( R-HSA-438066 ) R-HSA-432172 Reaction Name: Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor See in Reactome R-HSA-4332356 ( R-HSA-4086398 ) R-HSA-4332356 Reaction Name: CAMK2 binds MAP3K7 See in Reactome R-HSA-4332358 ( R-HSA-4086398 ) R-HSA-4332358 Reaction Name: Dissociation of CaM and CAMK2 autophosphorylation See in Reactome R-HSA-4332359 ( R-HSA-4086398 ) R-HSA-4332359 Reaction Name: Active calmodulin binds CAMK2 See in Reactome R-HSA-4332363 ( R-HSA-4086398 ) R-HSA-4332363 Reaction Name: Autophosphorylation and activation of CAMK2 See in Reactome R-HSA-4332388 ( R-HSA-4086398 ) R-HSA-4332388 Reaction Name: Activation of MAP3K7 in response to WNT See in Reactome R-HSA-438037 ( R-HSA-438066 ) R-HSA-438037 Reaction Name: Membrane depolarization upon activation of Ca impermeable AMPA receptors See in Reactome R-HSA-442725 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-442725 Reaction Name: CaMKII binds activated calmodulin See in Reactome R-HSA-442732 ( R-HSA-442982 ) R-HSA-442732 Reaction Name: NMDA-activated RASGRF1 activates RAS See in Reactome R-HSA-442760 ( R-HSA-442982 ) R-HSA-442760 Reaction Name: Activation of RasGRF See in Reactome R-HSA-445367 ( R-HSA-9620244 ) R-HSA-445367 Reaction Name: CaMKII binds activated NMDA receptor See in Reactome R-HSA-5082387 ( R-HSA-3371571 ) R-HSA-5082387 Reaction Name: Phosphorylation of HSF1 at Ser230 induces transactivation See in Reactome R-HSA-5576895 ( R-HSA-5576892 ) R-HSA-5576895 Reaction Name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol See in Reactome R-HSA-5672965 ( R-HSA-5673001 ) R-HSA-5672965 Reaction Name: RAS GEFs promote RAS nucleotide exchange See in Reactome R-HSA-5672969 ( R-HSA-5673000; R-HSA-5673001 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-9006992 ( R-HSA-8986944; R-HSA-9022692 ) R-HSA-9006992 Reaction Name: MECP2 is phosphorylated at S423 See in Reactome R-HSA-909552 ( R-HSA-877300 ) R-HSA-909552 Reaction Name: Phosphorylation of STAT1 at Ser727 See in Reactome R-HSA-9611368 ( R-HSA-9609736 ) R-HSA-9611368 Reaction Name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density See in Reactome R-HSA-9612085 ( R-HSA-9620244 ) R-HSA-9612085 Reaction Name: SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs See in Reactome R-HSA-9614185 ( R-HSA-438066 ) R-HSA-9614185 Reaction Name: Mg2+ binds GRIN1:GRIN2 NMDA receptors See in Reactome R-HSA-9617326 ( R-HSA-9617324 ) R-HSA-9617326 Reaction Name: CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 See in Reactome R-HSA-9617583 ( R-HSA-111932; R-HSA-9620244 ) R-HSA-9617583 Reaction Name: CaMKII autophosphorylates See in Reactome R-HSA-9618750 ( R-HSA-9620244 ) R-HSA-9618750 Reaction Name: CaMKII phosphorylates AMPA receptor See in Reactome R-HSA-9619449 ( R-HSA-9617324 ) R-HSA-9619449 Reaction Name: PPM1F dephosphorylates p-T286-CaMKII See in Reactome