DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-9013405)

Number of enzymes:	3
Number of disease:	7
Number of reactomes:	22
Number of reactions:	32

Search results (Reactome ID: R-HSA-9013405)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008214	LBR	Q14739	1.3.1.70	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-2995383 R-HSA-2995383 Reactome Name: Initiation of Nuclear Envelope (NE) Reformation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-2995410 R-HSA-2995410 Reactome Name: Nuclear Envelope (NE) Reassembly See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Cell Cycle Signal Transduction	R-HSA-194674 ( R-HSA-191273 ) R-HSA-194674 Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] See in Reactome R-HSA-9013004 ( R-HSA-8980692 ) R-HSA-9013004 Reaction Name: RHOA binds effectors at the ER membrane See in Reactome R-HSA-9013438 ( R-HSA-9013405 ) R-HSA-9013438 Reaction Name: RHOD binds effectors at the endosome membrane See in Reactome R-HSA-9014467 ( R-HSA-9013408 ) R-HSA-9014467 Reaction Name: RHOG binds effectors at the ER membrane See in Reactome R-HSA-9018594 ( R-HSA-9022692 ) R-HSA-9018594 Reaction Name: MECP2 binds LBR See in Reactome R-HSA-9624798 ( R-HSA-2995383 ) R-HSA-9624798 Reaction Name: LBR binds KPNB1 See in Reactome R-HSA-9624800 ( R-HSA-2995383 ) R-HSA-9624800 Reaction Name: CDK1 phosphorylates LBR See in Reactome R-HSA-9691174 ( R-HSA-9013149 ) R-HSA-9691174 Reaction Name: RAC1 binds effectors at the ER membrane See in Reactome R-HSA-9692809 ( R-HSA-9013148 ) R-HSA-9692809 Reaction Name: CDC42 binds effectors at the ER membrane See in Reactome R-HSA-9714361 ( R-HSA-9013106 ) R-HSA-9714361 Reaction Name: RHOC activates endoplasmic reticulum effectors See in Reactome R-HSA-9714481 ( R-HSA-9013404 ) R-HSA-9714481 Reaction Name: RAC2 binds effectors at the ER membrane See in Reactome R-HSA-9714691 ( R-HSA-9013423 ) R-HSA-9714691 Reaction Name: RAC3 binds ER effectors See in Reactome
MONDO:0008974	LBR	Q14739	1.3.1.70	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-2995383 R-HSA-2995383 Reactome Name: Initiation of Nuclear Envelope (NE) Reformation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-2995410 R-HSA-2995410 Reactome Name: Nuclear Envelope (NE) Reassembly See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Cell Cycle Signal Transduction	R-HSA-194674 ( R-HSA-191273 ) R-HSA-194674 Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] See in Reactome R-HSA-9013004 ( R-HSA-8980692 ) R-HSA-9013004 Reaction Name: RHOA binds effectors at the ER membrane See in Reactome R-HSA-9013438 ( R-HSA-9013405 ) R-HSA-9013438 Reaction Name: RHOD binds effectors at the endosome membrane See in Reactome R-HSA-9014467 ( R-HSA-9013408 ) R-HSA-9014467 Reaction Name: RHOG binds effectors at the ER membrane See in Reactome R-HSA-9018594 ( R-HSA-9022692 ) R-HSA-9018594 Reaction Name: MECP2 binds LBR See in Reactome R-HSA-9624798 ( R-HSA-2995383 ) R-HSA-9624798 Reaction Name: LBR binds KPNB1 See in Reactome R-HSA-9624800 ( R-HSA-2995383 ) R-HSA-9624800 Reaction Name: CDK1 phosphorylates LBR See in Reactome R-HSA-9691174 ( R-HSA-9013149 ) R-HSA-9691174 Reaction Name: RAC1 binds effectors at the ER membrane See in Reactome R-HSA-9692809 ( R-HSA-9013148 ) R-HSA-9692809 Reaction Name: CDC42 binds effectors at the ER membrane See in Reactome R-HSA-9714361 ( R-HSA-9013106 ) R-HSA-9714361 Reaction Name: RHOC activates endoplasmic reticulum effectors See in Reactome R-HSA-9714481 ( R-HSA-9013404 ) R-HSA-9714481 Reaction Name: RAC2 binds effectors at the ER membrane See in Reactome R-HSA-9714691 ( R-HSA-9013423 ) R-HSA-9714691 Reaction Name: RAC3 binds ER effectors See in Reactome
MONDO:0010949	RAB7A	P51149	3.6.5.2	R-HSA-8876198 R-HSA-8876198 Reactome Name: RAB GEFs exchange GTP for GDP on RABs See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013407 R-HSA-9013407 Reactome Name: RHOH GTPase cycle See in Reactome R-HSA-9013409 R-HSA-9013409 Reactome Name: RHOJ GTPase cycle See in Reactome R-HSA-8873719 R-HSA-8873719 Reactome Name: RAB geranylgeranylation See in Reactome R-HSA-8854214 R-HSA-8854214 Reactome Name: TBC/RABGAPs See in Reactome R-HSA-9035034 R-HSA-9035034 Reactome Name: RHOF GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-2132295 R-HSA-2132295 Reactome Name: MHC class II antigen presentation See in Reactome R-HSA-9013406 R-HSA-9013406 Reactome Name: RHOQ GTPase cycle See in Reactome R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-9007101 R-HSA-9007101 Reactome Name: Rab regulation of trafficking See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Immune System Metabolism of proteins Signal Transduction Vesicle-mediated transport	R-HSA-2213248 ( R-HSA-2132295 ) R-HSA-2213248 Reaction Name: Transport of antigen loaded MHC II molecules to surface See in Reactome R-HSA-6798743 ( R-HSA-6798695 ) R-HSA-6798743 Reaction Name: Exocytosis of secretory granule membrane proteins See in Reactome R-HSA-8854255 ( R-HSA-8854214 ) R-HSA-8854255 Reaction Name: TBC1D2A accelerates GTP hydrolysis by RAB7 See in Reactome R-HSA-8854329 ( R-HSA-8854214 ) R-HSA-8854329 Reaction Name: TBC1D15 accelerates GTP hydrolysis by RAB7 See in Reactome R-HSA-8870466 ( R-HSA-8873719 ) R-HSA-8870466 Reaction Name: RGGT:CHM binds RABs See in Reactome R-HSA-8870469 ( R-HSA-8873719 ) R-HSA-8870469 Reaction Name: RGGT geranylgeranylates RAB proteins See in Reactome R-HSA-8877451 ( R-HSA-8876198 ) R-HSA-8877451 Reaction Name: MON1:CCZ1 exchanges GTP for GDP on RAB7 See in Reactome R-HSA-9013145 ( R-HSA-9013149 ) R-HSA-9013145 Reaction Name: RAC1 binds effectors at the plasma membrane See in Reactome R-HSA-9013157 ( R-HSA-9013148 ) R-HSA-9013157 Reaction Name: CDC42 binds effectors at the plasma membrane See in Reactome R-HSA-9014294 ( R-HSA-9013404 ) R-HSA-9014294 Reaction Name: RAC2 binds effectors at the plasma membrane See in Reactome R-HSA-9014449 ( R-HSA-9013408 ) R-HSA-9014449 Reaction Name: RHOG binds effectors at the plasma membrane See in Reactome R-HSA-9017507 ( R-HSA-9013409 ) R-HSA-9017507 Reaction Name: RHOJ binds effectors at the plasma membrane See in Reactome R-HSA-9018746 ( R-HSA-9013406 ) R-HSA-9018746 Reaction Name: RHOQ binds effectors at the plasma membrane See in Reactome R-HSA-9018758 ( R-HSA-9013407 ) R-HSA-9018758 Reaction Name: RHOH binds effectors at the plasma membrane See in Reactome R-HSA-9018808 ( R-HSA-9013423 ) R-HSA-9018808 Reaction Name: RAC3 binds effectors at the plasma membrane See in Reactome R-HSA-9693125 ( R-HSA-9035034 ) R-HSA-9693125 Reaction Name: RHOF binds effectors at the plasma membrane See in Reactome R-HSA-9693198 ( R-HSA-9013405 ) R-HSA-9693198 Reaction Name: RHOD binds effectors at the plasma membrane See in Reactome
MONDO:0013276	LBR	Q14739	1.3.1.70	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-2995383 R-HSA-2995383 Reactome Name: Initiation of Nuclear Envelope (NE) Reformation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-2995410 R-HSA-2995410 Reactome Name: Nuclear Envelope (NE) Reassembly See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Cell Cycle Signal Transduction	R-HSA-194674 ( R-HSA-191273 ) R-HSA-194674 Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] See in Reactome R-HSA-9013004 ( R-HSA-8980692 ) R-HSA-9013004 Reaction Name: RHOA binds effectors at the ER membrane See in Reactome R-HSA-9013438 ( R-HSA-9013405 ) R-HSA-9013438 Reaction Name: RHOD binds effectors at the endosome membrane See in Reactome R-HSA-9014467 ( R-HSA-9013408 ) R-HSA-9014467 Reaction Name: RHOG binds effectors at the ER membrane See in Reactome R-HSA-9018594 ( R-HSA-9022692 ) R-HSA-9018594 Reaction Name: MECP2 binds LBR See in Reactome R-HSA-9624798 ( R-HSA-2995383 ) R-HSA-9624798 Reaction Name: LBR binds KPNB1 See in Reactome R-HSA-9624800 ( R-HSA-2995383 ) R-HSA-9624800 Reaction Name: CDK1 phosphorylates LBR See in Reactome R-HSA-9691174 ( R-HSA-9013149 ) R-HSA-9691174 Reaction Name: RAC1 binds effectors at the ER membrane See in Reactome R-HSA-9692809 ( R-HSA-9013148 ) R-HSA-9692809 Reaction Name: CDC42 binds effectors at the ER membrane See in Reactome R-HSA-9714361 ( R-HSA-9013106 ) R-HSA-9714361 Reaction Name: RHOC activates endoplasmic reticulum effectors See in Reactome R-HSA-9714481 ( R-HSA-9013404 ) R-HSA-9714481 Reaction Name: RAC2 binds effectors at the ER membrane See in Reactome R-HSA-9714691 ( R-HSA-9013423 ) R-HSA-9714691 Reaction Name: RAC3 binds ER effectors See in Reactome
MONDO:0014094	STEAP3	Q658P3	1.16.1.-	R-HSA-917977 R-HSA-917977 Reactome Name: Transferrin endocytosis and recycling See in Reactome R-HSA-9035034 R-HSA-9035034 Reactome Name: RHOF GTPase cycle See in Reactome R-HSA-6803204 R-HSA-6803204 Reactome Name: TP53 Regulates Transcription of Genes Involved in Cytochrome C Release See in Reactome R-HSA-9013409 R-HSA-9013409 Reactome Name: RHOJ GTPase cycle See in Reactome R-HSA-9013406 R-HSA-9013406 Reactome Name: RHOQ GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-5633008 R-HSA-5633008 Reactome Name: TP53 Regulates Transcription of Cell Death Genes See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-917937 R-HSA-917937 Reactome Name: Iron uptake and transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Transport of small molecules Signal Transduction	R-HSA-6801184 ( R-HSA-6803204 ) R-HSA-6801184 Reaction Name: TP53 stimulates STEAP3 expression See in Reactome R-HSA-6801195 ( R-HSA-6803204 ) R-HSA-6801195 Reaction Name: STEAP3 binds BNIP3L See in Reactome R-HSA-9013157 ( R-HSA-9013148 ) R-HSA-9013157 Reaction Name: CDC42 binds effectors at the plasma membrane See in Reactome R-HSA-9017507 ( R-HSA-9013409 ) R-HSA-9017507 Reaction Name: RHOJ binds effectors at the plasma membrane See in Reactome R-HSA-9018746 ( R-HSA-9013406 ) R-HSA-9018746 Reaction Name: RHOQ binds effectors at the plasma membrane See in Reactome R-HSA-917811 ( R-HSA-917977 ) R-HSA-917811 Reaction Name: STEAP3-like proteins reduce Fe3+ to Fe2+ See in Reactome R-HSA-9693125 ( R-HSA-9035034 ) R-HSA-9693125 Reaction Name: RHOF binds effectors at the plasma membrane See in Reactome R-HSA-9693198 ( R-HSA-9013405 ) R-HSA-9693198 Reaction Name: RHOD binds effectors at the plasma membrane See in Reactome
MONDO:0018663	LBR	Q14739	1.3.1.70	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-2995383 R-HSA-2995383 Reactome Name: Initiation of Nuclear Envelope (NE) Reformation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-2995410 R-HSA-2995410 Reactome Name: Nuclear Envelope (NE) Reassembly See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Cell Cycle Signal Transduction	R-HSA-194674 ( R-HSA-191273 ) R-HSA-194674 Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] See in Reactome R-HSA-9013004 ( R-HSA-8980692 ) R-HSA-9013004 Reaction Name: RHOA binds effectors at the ER membrane See in Reactome R-HSA-9013438 ( R-HSA-9013405 ) R-HSA-9013438 Reaction Name: RHOD binds effectors at the endosome membrane See in Reactome R-HSA-9014467 ( R-HSA-9013408 ) R-HSA-9014467 Reaction Name: RHOG binds effectors at the ER membrane See in Reactome R-HSA-9018594 ( R-HSA-9022692 ) R-HSA-9018594 Reaction Name: MECP2 binds LBR See in Reactome R-HSA-9624798 ( R-HSA-2995383 ) R-HSA-9624798 Reaction Name: LBR binds KPNB1 See in Reactome R-HSA-9624800 ( R-HSA-2995383 ) R-HSA-9624800 Reaction Name: CDK1 phosphorylates LBR See in Reactome R-HSA-9691174 ( R-HSA-9013149 ) R-HSA-9691174 Reaction Name: RAC1 binds effectors at the ER membrane See in Reactome R-HSA-9692809 ( R-HSA-9013148 ) R-HSA-9692809 Reaction Name: CDC42 binds effectors at the ER membrane See in Reactome R-HSA-9714361 ( R-HSA-9013106 ) R-HSA-9714361 Reaction Name: RHOC activates endoplasmic reticulum effectors See in Reactome R-HSA-9714481 ( R-HSA-9013404 ) R-HSA-9714481 Reaction Name: RAC2 binds effectors at the ER membrane See in Reactome R-HSA-9714691 ( R-HSA-9013423 ) R-HSA-9714691 Reaction Name: RAC3 binds ER effectors See in Reactome
MONDO:0018770	LBR	Q14739	1.3.1.70	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-2995383 R-HSA-2995383 Reactome Name: Initiation of Nuclear Envelope (NE) Reformation See in Reactome R-HSA-9022692 R-HSA-9022692 Reactome Name: Regulation of MECP2 expression and activity See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013408 R-HSA-9013408 Reactome Name: RHOG GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013405 R-HSA-9013405 Reactome Name: RHOD GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-2995410 R-HSA-2995410 Reactome Name: Nuclear Envelope (NE) Reassembly See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Cell Cycle Signal Transduction	R-HSA-194674 ( R-HSA-191273 ) R-HSA-194674 Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] See in Reactome R-HSA-9013004 ( R-HSA-8980692 ) R-HSA-9013004 Reaction Name: RHOA binds effectors at the ER membrane See in Reactome R-HSA-9013438 ( R-HSA-9013405 ) R-HSA-9013438 Reaction Name: RHOD binds effectors at the endosome membrane See in Reactome R-HSA-9014467 ( R-HSA-9013408 ) R-HSA-9014467 Reaction Name: RHOG binds effectors at the ER membrane See in Reactome R-HSA-9018594 ( R-HSA-9022692 ) R-HSA-9018594 Reaction Name: MECP2 binds LBR See in Reactome R-HSA-9624798 ( R-HSA-2995383 ) R-HSA-9624798 Reaction Name: LBR binds KPNB1 See in Reactome R-HSA-9624800 ( R-HSA-2995383 ) R-HSA-9624800 Reaction Name: CDK1 phosphorylates LBR See in Reactome R-HSA-9691174 ( R-HSA-9013149 ) R-HSA-9691174 Reaction Name: RAC1 binds effectors at the ER membrane See in Reactome R-HSA-9692809 ( R-HSA-9013148 ) R-HSA-9692809 Reaction Name: CDC42 binds effectors at the ER membrane See in Reactome R-HSA-9714361 ( R-HSA-9013106 ) R-HSA-9714361 Reaction Name: RHOC activates endoplasmic reticulum effectors See in Reactome R-HSA-9714481 ( R-HSA-9013404 ) R-HSA-9714481 Reaction Name: RAC2 binds effectors at the ER membrane See in Reactome R-HSA-9714691 ( R-HSA-9013423 ) R-HSA-9714691 Reaction Name: RAC3 binds ER effectors See in Reactome