MONDO:0003608 |
OAT |
P04181 |
2.6.1.13
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-70654
(
R-HSA-8964539
)
R-HSA-70654
Reaction Name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]
See in Reactome
R-HSA-70666
(
R-HSA-8964539
)
R-HSA-70666
Reaction Name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT]
See in Reactome
|
MONDO:0009053 |
ALDH18A1 |
P54886 |
2.7.2.11
1.2.1.41
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-508040
(
R-HSA-8964539
)
R-HSA-508040
Reaction Name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]
See in Reactome
|
MONDO:0009271 |
PYCR1 |
P32322 |
1.5.1.2
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-70664
(
R-HSA-8964539
)
R-HSA-70664
Reaction Name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro
See in Reactome
|
MONDO:0009734 |
GLUD1 |
P00367 |
1.4.1.3
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
R-HSA-2151201
R-HSA-2151201
Reactome Name: Transcriptional activation of mitochondrial biogenesis
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1852241
R-HSA-1852241
Reactome Name: Organelle biogenesis and maintenance
See in Reactome
R-HSA-1430728
R-HSA-1592230
|
Organelle biogenesis and maintenance
Metabolism
|
R-HSA-5688276
(
R-HSA-2151201
)
R-HSA-5688276
Reaction Name: SIRT4 transfers ADPRib to GLUD
See in Reactome
R-HSA-5688289
(
R-HSA-2151201
)
R-HSA-5688289
Reaction Name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2
See in Reactome
R-HSA-70589
(
R-HSA-8964539
)
R-HSA-70589
Reaction Name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1]
See in Reactome
R-HSA-70600
(
R-HSA-8964539
)
R-HSA-70600
Reaction Name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1]
See in Reactome
|
MONDO:0009796 |
OAT |
P04181 |
2.6.1.13
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-70654
(
R-HSA-8964539
)
R-HSA-70654
Reaction Name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT]
See in Reactome
R-HSA-70666
(
R-HSA-8964539
)
R-HSA-70666
Reaction Name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT]
See in Reactome
|
MONDO:0011006 |
ALDH18A1 |
P54886 |
2.7.2.11
1.2.1.41
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-508040
(
R-HSA-8964539
)
R-HSA-508040
Reaction Name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]
See in Reactome
|
MONDO:0011717 |
GLUD1 |
P00367 |
1.4.1.3
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
R-HSA-2151201
R-HSA-2151201
Reactome Name: Transcriptional activation of mitochondrial biogenesis
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1852241
R-HSA-1852241
Reactome Name: Organelle biogenesis and maintenance
See in Reactome
R-HSA-1430728
R-HSA-1592230
|
Organelle biogenesis and maintenance
Metabolism
|
R-HSA-5688276
(
R-HSA-2151201
)
R-HSA-5688276
Reaction Name: SIRT4 transfers ADPRib to GLUD
See in Reactome
R-HSA-5688289
(
R-HSA-2151201
)
R-HSA-5688289
Reaction Name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2
See in Reactome
R-HSA-70589
(
R-HSA-8964539
)
R-HSA-70589
Reaction Name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1]
See in Reactome
R-HSA-70600
(
R-HSA-8964539
)
R-HSA-70600
Reaction Name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1]
See in Reactome
|
MONDO:0012393 |
GLUL |
P15104 |
2.3.1.225
6.3.1.2
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
R-HSA-210455
R-HSA-210455
Reactome Name: Astrocytic Glutamate-Glutamine Uptake And Metabolism
See in Reactome
|
R-HSA-112316
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-1430728
R-HSA-112313
R-HSA-112313
Reactome Name: Neurotransmitter uptake and metabolism In glial cells
See in Reactome
|
Neuronal System
Metabolism
|
R-HSA-70606
(
R-HSA-210455;
R-HSA-8964539
)
R-HSA-70606
Reaction Name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]
See in Reactome
|
MONDO:0013051 |
PYCR1 |
P32322 |
1.5.1.2
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-70664
(
R-HSA-8964539
)
R-HSA-70664
Reaction Name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro
See in Reactome
|
MONDO:0013755 |
PYCR1 |
P32322 |
1.5.1.2
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-70664
(
R-HSA-8964539
)
R-HSA-70664
Reaction Name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro
See in Reactome
|
MONDO:0014632 |
PYCR2 |
Q96C36 |
1.5.1.2
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-6783939
(
R-HSA-8964539
)
R-HSA-6783939
Reaction Name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro
See in Reactome
|
MONDO:0014702 |
ALDH18A1 |
P54886 |
2.7.2.11
1.2.1.41
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-508040
(
R-HSA-8964539
)
R-HSA-508040
Reaction Name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]
See in Reactome
|
MONDO:0014706 |
ALDH18A1 |
P54886 |
2.7.2.11
1.2.1.41
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-508040
(
R-HSA-8964539
)
R-HSA-508040
Reaction Name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]
See in Reactome
|
MONDO:0016660 |
PYCR2 |
Q96C36 |
1.5.1.2
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-6783939
(
R-HSA-8964539
)
R-HSA-6783939
Reaction Name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro
See in Reactome
|
MONDO:0018644 |
ALDH18A1 |
P54886 |
2.7.2.11
1.2.1.41
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-508040
(
R-HSA-8964539
)
R-HSA-508040
Reaction Name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS]
See in Reactome
|
MONDO:0018825 |
PYCR2 |
Q96C36 |
1.5.1.2
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-6783939
(
R-HSA-8964539
)
R-HSA-6783939
Reaction Name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro
See in Reactome
|
MONDO:0024457 |
PYCR1 |
P32322 |
1.5.1.2
|
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
|
Metabolism
|
R-HSA-70664
(
R-HSA-8964539
)
R-HSA-70664
Reaction Name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro
See in Reactome
|
MONDO:0032678 |
GLS |
O94925 |
3.5.1.2
|
R-HSA-210500
R-HSA-210500
Reactome Name: Glutamate Neurotransmitter Release Cycle
See in Reactome
R-HSA-5628897
R-HSA-5628897
Reactome Name: TP53 Regulates Metabolic Genes
See in Reactome
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-1430728
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-112316
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-112310
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Neuronal System
|
R-HSA-70609
(
R-HSA-210500;
R-HSA-5628897;
R-HSA-8964539
)
R-HSA-70609
Reaction Name: glutamine + H2O => glutamate + NH4+ [GLS]
See in Reactome
|
MONDO:0032685 |
GLS |
O94925 |
3.5.1.2
|
R-HSA-210500
R-HSA-210500
Reactome Name: Glutamate Neurotransmitter Release Cycle
See in Reactome
R-HSA-5628897
R-HSA-5628897
Reactome Name: TP53 Regulates Metabolic Genes
See in Reactome
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-1430728
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-112316
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-112310
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Neuronal System
|
R-HSA-70609
(
R-HSA-210500;
R-HSA-5628897;
R-HSA-8964539
)
R-HSA-70609
Reaction Name: glutamine + H2O => glutamate + NH4+ [GLS]
See in Reactome
|
MONDO:0032733 |
GLS |
O94925 |
3.5.1.2
|
R-HSA-210500
R-HSA-210500
Reactome Name: Glutamate Neurotransmitter Release Cycle
See in Reactome
R-HSA-5628897
R-HSA-5628897
Reactome Name: TP53 Regulates Metabolic Genes
See in Reactome
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-1430728
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-112316
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-112310
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Neuronal System
|
R-HSA-70609
(
R-HSA-210500;
R-HSA-5628897;
R-HSA-8964539
)
R-HSA-70609
Reaction Name: glutamine + H2O => glutamate + NH4+ [GLS]
See in Reactome
|
MONDO:0032880 |
GOT2 |
P00505 |
2.6.1.7
2.6.1.1
|
R-HSA-389661
R-HSA-389661
Reactome Name: Glyoxylate metabolism and glycine degradation
See in Reactome
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
R-HSA-1614558
R-HSA-1614558
Reactome Name: Degradation of cysteine and homocysteine
See in Reactome
R-HSA-8963693
R-HSA-8963693
Reactome Name: Aspartate and asparagine metabolism
See in Reactome
R-HSA-70263
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1614635
R-HSA-1430728
R-HSA-70326
R-HSA-71387
|
Metabolism
|
R-HSA-6784393
(
R-HSA-389661
)
R-HSA-6784393
Reaction Name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG)
See in Reactome
R-HSA-70596
(
R-HSA-8963693
)
R-HSA-70613
(
R-HSA-70263;
R-HSA-8964539
)
R-HSA-70613
Reaction Name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]
See in Reactome
R-HSA-9012597
(
R-HSA-1614558
)
R-HSA-9012597
Reaction Name: GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu
See in Reactome
|
MONDO:0034146 |
GLS |
O94925 |
3.5.1.2
|
R-HSA-210500
R-HSA-210500
Reactome Name: Glutamate Neurotransmitter Release Cycle
See in Reactome
R-HSA-5628897
R-HSA-5628897
Reactome Name: TP53 Regulates Metabolic Genes
See in Reactome
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-1430728
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-112316
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-112310
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Neuronal System
|
R-HSA-70609
(
R-HSA-210500;
R-HSA-5628897;
R-HSA-8964539
)
R-HSA-70609
Reaction Name: glutamine + H2O => glutamate + NH4+ [GLS]
See in Reactome
|
MONDO:0034147 |
GLS |
O94925 |
3.5.1.2
|
R-HSA-210500
R-HSA-210500
Reactome Name: Glutamate Neurotransmitter Release Cycle
See in Reactome
R-HSA-5628897
R-HSA-5628897
Reactome Name: TP53 Regulates Metabolic Genes
See in Reactome
R-HSA-8964539
R-HSA-8964539
Reactome Name: Glutamate and glutamine metabolism
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-1430728
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-112316
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-112310
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Neuronal System
|
R-HSA-70609
(
R-HSA-210500;
R-HSA-5628897;
R-HSA-8964539
)
R-HSA-70609
Reaction Name: glutamine + H2O => glutamate + NH4+ [GLS]
See in Reactome
|