DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-8964058)

Number of enzymes:	2
Number of disease:	3
Number of reactomes:	3
Number of reactions:	9

Search results (Reactome ID: R-HSA-8964058)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007620	LCAT	P04180	3.1.1.47 2.3.1.43	R-HSA-8964058 R-HSA-8964058 Reactome Name: HDL remodeling See in Reactome	R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-8963899 R-HSA-8963899 Reactome Name: Plasma lipoprotein remodeling See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-264678 ( R-HSA-8964058 ) R-HSA-264678 Reaction Name: LCAT + discoidal HDL <=> LCAT:discoidal HDL complex See in Reactome R-HSA-264689 ( R-HSA-8964058 ) R-HSA-264689 Reaction Name: LCAT:discoidal HDL complex <=> LCAT + discoidal HDL See in Reactome R-HSA-264695 ( R-HSA-8964058 ) R-HSA-264695 Reaction Name: cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) See in Reactome R-HSA-266310 ( R-HSA-8964058 ) R-HSA-266310 Reaction Name: LCAT:spherical HDL complex <=> LCAT + spherical HDL See in Reactome R-HSA-266315 ( R-HSA-8964058 ) R-HSA-266315 Reaction Name: LCAT + spherical HDL <=> LCAT:spherical HDL complex See in Reactome
MONDO:0007744	CETP	P11597	-	R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8964058 R-HSA-8964058 Reactome Name: HDL remodeling See in Reactome R-HSA-8964041 R-HSA-8964041 Reactome Name: LDL remodeling See in Reactome	R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-8963899 R-HSA-8963899 Reactome Name: Plasma lipoprotein remodeling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome	Transport of small molecules Signal Transduction	R-HSA-266328 ( R-HSA-8964058 ) R-HSA-266328 Reaction Name: CETP-mediated lipid exchange: spherical HDL gains triacylglycerol See in Reactome R-HSA-266350 ( R-HSA-8964041 ) R-HSA-266350 Reaction Name: CETP-mediated lipid exchange: LDL gains cholesterol ester See in Reactome R-HSA-349404 ( R-HSA-8964058 ) R-HSA-349404 Reaction Name: CETP + spherical HDL + torcetrapib => CETP:spherical HDL:torcetrapib complex See in Reactome R-HSA-9035169 ( R-HSA-9029569 ) R-HSA-9035169 Reaction Name: Expression of CETP regulated by NR1H2 or NR1H3 See in Reactome
MONDO:0009515	LCAT	P04180	3.1.1.47 2.3.1.43	R-HSA-8964058 R-HSA-8964058 Reactome Name: HDL remodeling See in Reactome	R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-8963899 R-HSA-8963899 Reactome Name: Plasma lipoprotein remodeling See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-264678 ( R-HSA-8964058 ) R-HSA-264678 Reaction Name: LCAT + discoidal HDL <=> LCAT:discoidal HDL complex See in Reactome R-HSA-264689 ( R-HSA-8964058 ) R-HSA-264689 Reaction Name: LCAT:discoidal HDL complex <=> LCAT + discoidal HDL See in Reactome R-HSA-264695 ( R-HSA-8964058 ) R-HSA-264695 Reaction Name: cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) See in Reactome R-HSA-266310 ( R-HSA-8964058 ) R-HSA-266310 Reaction Name: LCAT:spherical HDL complex <=> LCAT + spherical HDL See in Reactome R-HSA-266315 ( R-HSA-8964058 ) R-HSA-266315 Reaction Name: LCAT + spherical HDL <=> LCAT:spherical HDL complex See in Reactome