MONDO:0001187 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0005012 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0005097 |
EP300 |
Q09472 |
2.3.1.-
2.3.1.48
|
R-HSA-9617629
R-HSA-9617629
Reactome Name: Regulation of FOXO transcriptional activity by acetylation
See in Reactome
R-HSA-210744
R-HSA-210744
Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
See in Reactome
R-HSA-5689901
R-HSA-6804760
R-HSA-6804760
Reactome Name: Regulation of TP53 Activity through Methylation
See in Reactome
R-HSA-8939243
R-HSA-8939243
Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
See in Reactome
R-HSA-381340
R-HSA-381340
Reactome Name: Transcriptional regulation of white adipocyte differentiation
See in Reactome
R-HSA-9616222
R-HSA-9616222
Reactome Name: Transcriptional regulation of granulopoiesis
See in Reactome
R-HSA-9013695
R-HSA-9013695
Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-6782135
R-HSA-6782210
R-HSA-6782210
Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER
See in Reactome
R-HSA-8941856
R-HSA-8941856
Reactome Name: RUNX3 regulates NOTCH signaling
See in Reactome
R-HSA-8941858
R-HSA-8941858
Reactome Name: Regulation of RUNX3 expression and activity
See in Reactome
R-HSA-6804114
R-HSA-6804114
Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
See in Reactome
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-918233
R-HSA-918233
Reactome Name: TRAF3-dependent IRF activation pathway
See in Reactome
R-HSA-6781827
R-HSA-6781827
Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
See in Reactome
R-HSA-156711
R-HSA-156711
Reactome Name: Polo-like kinase mediated events
See in Reactome
R-HSA-5250924
R-HSA-5250924
Reactome Name: B-WICH complex positively regulates rRNA expression
See in Reactome
R-HSA-6781823
R-HSA-6781823
Reactome Name: Formation of TC-NER Pre-Incision Complex
See in Reactome
R-HSA-9013508
R-HSA-9013508
Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-3214847
R-HSA-3371568
R-HSA-8866907
R-HSA-8866907
Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors
See in Reactome
R-HSA-9614657
R-HSA-9614657
Reactome Name: FOXO-mediated transcription of cell death genes
See in Reactome
R-HSA-9701898
R-HSA-9701898
Reactome Name: STAT3 nuclear events downstream of ALK signaling
See in Reactome
R-HSA-933541
R-HSA-1234158
R-HSA-1234158
Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor
See in Reactome
R-HSA-1368082
R-HSA-1368082
Reactome Name: RORA activates gene expression
See in Reactome
R-HSA-5617472
R-HSA-5617472
Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis
See in Reactome
R-HSA-3899300
R-HSA-3899300
Reactome Name: SUMOylation of transcription cofactors
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8936459
R-HSA-8936459
Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-2197563
R-HSA-2197563
Reactome Name: NOTCH2 intracellular domain regulates transcription
See in Reactome
R-HSA-400253
R-HSA-9707616
R-HSA-3134973
R-HSA-3134973
Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
See in Reactome
R-HSA-201722
R-HSA-201722
Reactome Name: Formation of the beta-catenin:TCF transactivating complex
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8951936
R-HSA-5621575
R-HSA-9031628
R-HSA-6811555
R-HSA-6811555
Reactome Name: PI5P Regulates TP53 Acetylation
See in Reactome
R-HSA-6804758
R-HSA-6804758
Reactome Name: Regulation of TP53 Activity through Acetylation
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-9012852
R-HSA-5633007
R-HSA-168256
R-HSA-9013694
R-HSA-168928
R-HSA-168928
Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta
See in Reactome
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-6791312
R-HSA-6791312
Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-1430728
R-HSA-8864260
R-HSA-8864260
Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-2262752
R-HSA-73894
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-2990846
R-HSA-556833
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-8953897
R-HSA-212165
R-HSA-212165
Reactome Name: Epigenetic regulation of gene expression
See in Reactome
R-HSA-5696398
R-HSA-168249
R-HSA-453274
R-HSA-392499
R-HSA-1234174
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-1980143
R-HSA-8939211
R-HSA-1834949
R-HSA-1834949
Reactome Name: Cytosolic sensors of pathogen-associated DNA
See in Reactome
R-HSA-186712
R-HSA-186712
Reactome Name: Regulation of beta-cell development
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-157118
R-HSA-187037
R-HSA-3247509
R-HSA-195721
R-HSA-1980145
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9614085
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-5688426
R-HSA-201556
R-HSA-5250913
R-HSA-5250913
Reactome Name: Positive epigenetic regulation of rRNA expression
See in Reactome
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-4839726
R-HSA-69275
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-162582
R-HSA-5619507
R-HSA-5619507
Reactome Name: Activation of HOX genes during differentiation
See in Reactome
|
Circadian Clock
Immune System
Cell Cycle
Developmental Biology
Metabolism
Gene expression (Transcription)
DNA Repair
Cellular responses to stimuli
Metabolism of proteins
Chromatin organization
Signal Transduction
|
R-HSA-6782069
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782069
Reaction Name: UVSSA:USP7 deubiquitinates ERCC6
See in Reactome
R-HSA-9760081
()
R-HSA-9760081
Reaction Name: CREBBP, EP300 acetylates NFE2L2
See in Reactome
R-HSA-9011981
(
R-HSA-9018519
)
R-HSA-9011981
Reaction Name: EP300 is recruited to MYC and BCL2 genes
See in Reactome
R-HSA-8878050
(
R-HSA-8939243
)
R-HSA-8878050
Reaction Name: HIPK2 phosphorylates RUNX1 and EP300
See in Reactome
R-HSA-9761836
()
R-HSA-9761836
Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300
See in Reactome
R-HSA-560491
(
R-HSA-381340
)
R-HSA-4396371
(
R-HSA-2122947
)
R-HSA-4396371
Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter
See in Reactome
R-HSA-9038052
(
R-HSA-9018519
)
R-HSA-9038052
Reaction Name: GREB1 binds ESR1:ESTG and co-activators
See in Reactome
R-HSA-8952101
(
R-HSA-8951936
)
R-HSA-8952101
Reaction Name: p14-ARF transcription is stimulated by RUNX proteins
See in Reactome
R-HSA-1234167
(
R-HSA-1234158
)
R-HSA-1234167
Reaction Name: Formation of HIF:CBP:p300 complex at promoters
See in Reactome
R-HSA-9617758
(
R-HSA-9617629
)
R-HSA-9038163
(
R-HSA-9018519
)
R-HSA-9038163
Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
See in Reactome
R-HSA-9016751
(
R-HSA-9013508
)
R-HSA-9016751
Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3
See in Reactome
R-HSA-6782211
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782211
Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site
See in Reactome
R-HSA-560498
(
R-HSA-381340
)
R-HSA-560498
Reaction Name: Expression of Lipoprotein lipase (LPL)
See in Reactome
R-HSA-1980065
(
R-HSA-2122947
)
R-HSA-1980065
Reaction Name: NOTCH1 stimulates HEY transcription
See in Reactome
R-HSA-9759332
()
R-HSA-9759332
Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter
See in Reactome
R-HSA-9613451
(
R-HSA-9031628
)
R-HSA-9613451
Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
See in Reactome
R-HSA-8936621
(
R-HSA-8936459
)
R-HSA-8936621
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
See in Reactome
R-HSA-5628871
(
R-HSA-6804758
)
R-HSA-5628871
Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53
See in Reactome
R-HSA-1980067
(
R-HSA-2122947
)
R-HSA-1980067
Reaction Name: NOTCH1 stimulates MYC transcription
See in Reactome
R-HSA-9620723
(
R-HSA-9031628
)
R-HSA-5250938
(
R-HSA-5250924
)
R-HSA-5250938
Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
See in Reactome
R-HSA-6782204
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782204
Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
See in Reactome
R-HSA-5617867
(
R-HSA-5617472
)
R-HSA-9761849
()
R-HSA-9761849
Reaction Name: AcK-NFE2L2-dependent P6GD gene expression
See in Reactome
R-HSA-9023884
(
R-HSA-9018519
)
R-HSA-9023884
Reaction Name: NCOA1 recruits EP300 to TGFA promoter
See in Reactome
R-HSA-8937050
(
R-HSA-8936459
)
R-HSA-8937050
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
See in Reactome
R-HSA-8952081
(
R-HSA-8951936
)
R-HSA-8952081
Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
See in Reactome
R-HSA-3662335
(
R-HSA-3214847
)
R-HSA-3662335
Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4
See in Reactome
R-HSA-1183003
(
R-HSA-381340
)
R-HSA-6804379
(
R-HSA-6804760
)
R-HSA-4088162
(
R-HSA-156711
)
R-HSA-3134883
(
R-HSA-3134973
)
R-HSA-3134883
Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300
See in Reactome
R-HSA-381309
(
R-HSA-381340
)
R-HSA-381309
Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands
See in Reactome
R-HSA-9023846
(
R-HSA-9018519
)
R-HSA-9023846
Reaction Name: Estrogen-responsive CTSD expression
See in Reactome
R-HSA-1028820
(
R-HSA-933541
)
R-HSA-1028820
Reaction Name: Formation of VAF (virus-activated factor) complex
See in Reactome
R-HSA-8878243
(
R-HSA-8941856
)
R-HSA-8878243
Reaction Name: HES1 gene transcription is inhibited by RUNX3
See in Reactome
R-HSA-9021450
(
R-HSA-9013508
)
R-HSA-9021450
Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes
See in Reactome
R-HSA-9761828
()
R-HSA-1028817
(
R-HSA-918233
)
R-HSA-1028817
Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3
See in Reactome
R-HSA-9008315
(
R-HSA-9018519
)
R-HSA-9008315
Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen
See in Reactome
R-HSA-8936628
(
R-HSA-8936459
)
R-HSA-8936628
Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9023860
(
R-HSA-9018519
)
R-HSA-9023860
Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene
See in Reactome
R-HSA-9761846
()
R-HSA-9761846
Reaction Name: NFE2L2-dependent PGD gene expression
See in Reactome
R-HSA-8936481
(
R-HSA-8936459
)
R-HSA-8936481
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
See in Reactome
R-HSA-5663264
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-6805650
(
R-HSA-6804758
)
R-HSA-6805650
Reaction Name: MTA2-NuRD complex deacetylates TP53
See in Reactome
R-HSA-5617452
(
R-HSA-5617472
)
R-HSA-5617452
Reaction Name: Retinoic acid activates HOXB1 chromatin
See in Reactome
R-HSA-4396347
(
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-4396347
Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter
See in Reactome
R-HSA-9759141
()
R-HSA-9759141
Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene
See in Reactome
R-HSA-9760125
()
R-HSA-9760125
Reaction Name: AcK-NFE2L2-dependent GCLM gene expression
See in Reactome
R-HSA-9613460
(
R-HSA-9031628
)
R-HSA-9620717
(
R-HSA-9031628
)
R-HSA-9620717
Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter
See in Reactome
R-HSA-8951951
(
R-HSA-8951936
)
R-HSA-9029561
(
R-HSA-9029569
)
R-HSA-9029561
Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter
See in Reactome
R-HSA-560473
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-9622604
(
R-HSA-9614657
)
R-HSA-9622604
Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y
See in Reactome
R-HSA-9617064
(
R-HSA-9616222
)
R-HSA-9617064
Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
See in Reactome
R-HSA-9008285
(
R-HSA-9018519
)
R-HSA-9008285
Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
See in Reactome
R-HSA-3371554
(
R-HSA-3371568
)
R-HSA-9701531
(
R-HSA-9701898
)
R-HSA-9701531
Reaction Name: p-Y705,S727 STAT3 is acetylated
See in Reactome
R-HSA-9017835
(
R-HSA-1912408
)
R-HSA-9017835
Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene
See in Reactome
R-HSA-8937097
(
R-HSA-8936459
)
R-HSA-8937097
Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-8936616
(
R-HSA-8936459
)
R-HSA-8936616
Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene
See in Reactome
R-HSA-5663246
(
R-HSA-400253
)
R-HSA-6804229
(
R-HSA-6804760
)
R-HSA-1801587
(
R-HSA-1368082;
R-HSA-1989781;
R-HSA-400253
)
R-HSA-8878056
(
R-HSA-8939243
)
R-HSA-9761812
()
R-HSA-9761812
Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
See in Reactome
R-HSA-4396382
(
R-HSA-2122947
)
R-HSA-4396382
Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes
See in Reactome
R-HSA-5617454
(
R-HSA-5617472
)
R-HSA-560510
(
R-HSA-381340
)
R-HSA-9760097
()
R-HSA-9760097
Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene
See in Reactome
R-HSA-6782004
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782004
Reaction Name: Assembly of the pre-incision complex in TC-NER
See in Reactome
R-HSA-5250930
(
R-HSA-5250924
)
R-HSA-5250930
Reaction Name: B-WICH recruits histone acetyltransferases
See in Reactome
R-HSA-8937016
(
R-HSA-8936459
)
R-HSA-8937016
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
See in Reactome
R-HSA-400342
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-6782138
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782138
Reaction Name: ERCC5 and RPA bind TC-NER site
See in Reactome
R-HSA-5617859
(
R-HSA-5617472
)
R-HSA-5617859
Reaction Name: Retinoic acid activates HOXB4 chromatin
See in Reactome
R-HSA-8952058
(
R-HSA-8951936
)
R-HSA-8952058
Reaction Name: CCND1 binds RUNX3 and displaces EP300
See in Reactome
R-HSA-1980047
(
R-HSA-210744;
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-1980047
Reaction Name: NOTCH1 stimulates HES1 transcription
See in Reactome
R-HSA-1235037
(
R-HSA-1234158
)
R-HSA-8878237
(
R-HSA-8941856
)
R-HSA-8878237
Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter
See in Reactome
R-HSA-9622579
(
R-HSA-9614657
)
R-HSA-9622579
Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter
See in Reactome
R-HSA-9620515
(
R-HSA-9617629
)
R-HSA-9620515
Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress
See in Reactome
R-HSA-933536
(
R-HSA-933541
)
R-HSA-933536
Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300
See in Reactome
R-HSA-9760128
()
R-HSA-9760128
Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression
See in Reactome
R-HSA-9617683
(
R-HSA-9617629
)
R-HSA-9617683
Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4
See in Reactome
R-HSA-1912415
(
R-HSA-1912408
)
R-HSA-1028812
(
R-HSA-918233
)
R-HSA-5693644
(
R-HSA-5617472
)
R-HSA-5693644
Reaction Name: HOXB1 maintains activation of HOXB1 chromatin
See in Reactome
R-HSA-9760082
()
R-HSA-1912394
(
R-HSA-2122947
)
R-HSA-1912394
Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML
See in Reactome
R-HSA-560493
(
R-HSA-381340
)
R-HSA-5617862
(
R-HSA-5617472
)
R-HSA-5617862
Reaction Name: Retinoic acid activates HOXA4 chromatin
See in Reactome
R-HSA-560517
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-560517
Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT)
See in Reactome
R-HSA-1912393
(
R-HSA-2122947
)
R-HSA-1912393
Reaction Name: MAML in complex with NICD1 recruits CDK8
See in Reactome
R-HSA-8935731
(
R-HSA-8936459
)
R-HSA-8935731
Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-6782208
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782208
Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
See in Reactome
R-HSA-5663293
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-1028819
(
R-HSA-933541
)
R-HSA-1028819
Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes
See in Reactome
R-HSA-5660666
(
R-HSA-5621575
)
R-HSA-5660666
Reaction Name: CBP and p300 binds NF-kB complex
See in Reactome
R-HSA-1912416
(
R-HSA-1912408
)
R-HSA-1912391
(
R-HSA-2122947
)
R-HSA-1912391
Reaction Name: NICD1 is phosphorylated by CDK8
See in Reactome
R-HSA-9761815
()
R-HSA-9761815
Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene
See in Reactome
R-HSA-549475
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-9760122
()
R-HSA-9760122
Reaction Name: AcK-NFE2L2-dependent GCLC gene expression
See in Reactome
R-HSA-6782227
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782227
Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER
See in Reactome
R-HSA-6811508
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-6811508
Reaction Name: ING2-bound EP300 acetylates TP53
See in Reactome
R-HSA-1235035
(
R-HSA-1234158
)
R-HSA-1235035
Reaction Name: Expression of Carbonic Anhydrase IX (CA9)
See in Reactome
R-HSA-9021451
(
R-HSA-9013508
)
R-HSA-9021451
Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter
See in Reactome
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9023840
(
R-HSA-9018519
)
R-HSA-9023840
Reaction Name: HATs and coactivators are recruited to the CTSD gene
See in Reactome
R-HSA-6811479
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-5617877
(
R-HSA-5617472
)
R-HSA-8864307
(
R-HSA-8866907
)
R-HSA-8864307
Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
See in Reactome
R-HSA-1028815
(
R-HSA-918233
)
R-HSA-1028815
Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta
See in Reactome
R-HSA-6804383
(
R-HSA-6804760
)
R-HSA-6782234
(
R-HSA-6781827
)
R-HSA-6782234
Reaction Name: Recovery of RNA synthesis after TC-NER
See in Reactome
R-HSA-9011975
(
R-HSA-9018519
)
R-HSA-9011975
Reaction Name: Estrogen-responsive MYC gene expression
See in Reactome
R-HSA-8878220
(
R-HSA-8941856
)
R-HSA-8878220
Reaction Name: RUNX3 binds the NOTCH1 coactivator complex
See in Reactome
R-HSA-2976551
(
R-HSA-2197563
)
R-HSA-2976551
Reaction Name: NOTCH2 stimulates GZMB transcription
See in Reactome
R-HSA-1368081
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-5617431
(
R-HSA-5617472
)
R-HSA-5617431
Reaction Name: Retinoic acid activates HOXA1 chromatin
See in Reactome
R-HSA-1980078
(
R-HSA-2122947
)
R-HSA-1980078
Reaction Name: NOTCH1 stimulates HES5 transcription
See in Reactome
R-HSA-4396379
(
R-HSA-2122947
)
R-HSA-4396379
Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter
See in Reactome
R-HSA-3215152
(
R-HSA-6804114
)
R-HSA-3215152
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
See in Reactome
R-HSA-4088152
(
R-HSA-156711
)
R-HSA-4088152
Reaction Name: FOXM1 stimulates CDC25A transcription
See in Reactome
R-HSA-9009371
(
R-HSA-9018519
)
R-HSA-9009371
Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter
See in Reactome
R-HSA-9023859
(
R-HSA-9018519
)
R-HSA-9023859
Reaction Name: Estrogen-responsive TFF1 gene expression
See in Reactome
R-HSA-1368087
(
R-HSA-400253
)
R-HSA-1368087
Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene
See in Reactome
R-HSA-1368065
(
R-HSA-1989781;
R-HSA-400253;
R-HSA-9707616
)
R-HSA-1183058
(
R-HSA-381340
)
R-HSA-9622572
(
R-HSA-9614657
)
R-HSA-9622572
Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
See in Reactome
R-HSA-3899291
(
R-HSA-3899300
)
R-HSA-3899291
Reaction Name: SUMOylation of EP300 with SUMO1
See in Reactome
R-HSA-9634433
(
R-HSA-9616222
)
R-HSA-9634433
Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid
See in Reactome
R-HSA-9605057
(
R-HSA-9029569
)
R-HSA-9605057
Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3
See in Reactome
R-HSA-5617471
(
R-HSA-5617472
)
R-HSA-9761841
()
R-HSA-9761841
Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression
See in Reactome
R-HSA-5691381
(
R-HSA-5689901
)
R-HSA-5691381
Reaction Name: MYSM1 deubiquitinates Histone H2A
See in Reactome
R-HSA-5617874
(
R-HSA-5617472
)
R-HSA-9760099
()
R-HSA-9760099
Reaction Name: AcK-NFE2L2 binds the GCLC gene
See in Reactome
R-HSA-9018499
(
R-HSA-9018519
)
R-HSA-9018499
Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter
See in Reactome
R-HSA-9760103
()
R-HSA-9760103
Reaction Name: AcK-NFE2L2 binds the GCLM gene
See in Reactome
R-HSA-560472
(
R-HSA-381340
)
R-HSA-560472
Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
See in Reactome
R-HSA-6782131
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782131
Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-8935740
(
R-HSA-8936459
)
R-HSA-8935740
Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene
See in Reactome
R-HSA-9009378
(
R-HSA-9018519
)
R-HSA-9009378
Reaction Name: Estrogen-responsive CCND1 gene expression
See in Reactome
R-HSA-8952419
(
R-HSA-8941858
)
R-HSA-6782224
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782224
Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER
See in Reactome
R-HSA-8936979
(
R-HSA-8936459
)
R-HSA-8936979
Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene
See in Reactome
R-HSA-1235070
(
R-HSA-1234158
)
R-HSA-1235070
Reaction Name: Expression of Erythropoietin (EPO)
See in Reactome
R-HSA-5660660
(
R-HSA-5621575
)
R-HSA-3215144
(
R-HSA-6804114
)
R-HSA-3215144
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription
See in Reactome
R-HSA-8951966
(
R-HSA-8951936
)
R-HSA-9008271
(
R-HSA-9018519
)
R-HSA-9008271
Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
See in Reactome
R-HSA-9011941
(
R-HSA-9018519
)
R-HSA-9011941
Reaction Name: Estrogen-responsive BCL2 gene expression
See in Reactome
R-HSA-2976563
(
R-HSA-2197563
)
R-HSA-2976563
Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
See in Reactome
R-HSA-5663273
(
R-HSA-400253
)
R-HSA-5663273
Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene
See in Reactome
R-HSA-9604499
(
R-HSA-933541
)
R-HSA-9604499
Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300
See in Reactome
R-HSA-9604664
(
R-HSA-9013695
)
R-HSA-9604664
Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
See in Reactome
R-HSA-6782141
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782141
Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
See in Reactome
R-HSA-5617896
(
R-HSA-5617472
)
R-HSA-5617896
Reaction Name: Retinoic acid activates HOXD4 chromatin
See in Reactome
R-HSA-8937037
(
R-HSA-8936459
)
R-HSA-8937037
Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene
See in Reactome
R-HSA-9759364
()
R-HSA-9759364
Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression
See in Reactome
R-HSA-9617735
(
R-HSA-9617629
)
R-HSA-9617735
Reaction Name: TXN disrupts FOXO4 complex with EP300
See in Reactome
R-HSA-3322427
(
R-HSA-201722
)
R-HSA-3322427
Reaction Name: Beta-catenin recruits CBP/p300
See in Reactome
R-HSA-9018497
(
R-HSA-9018519
)
R-HSA-9018497
Reaction Name: Estrogen-responsive TFF3 gene expression
See in Reactome
R-HSA-8936995
(
R-HSA-8936459
)
R-HSA-8936995
Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9684118
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-9684118
Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-6804242
(
R-HSA-6804760
)
R-HSA-6804242
Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5
See in Reactome
R-HSA-9759186
()
R-HSA-9759186
Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression
See in Reactome
R-HSA-3222093
(
R-HSA-6804758
)
|
MONDO:0005233 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0005335 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0005575 |
MONDO:0005575
Disease Name: colorectal cancer
OMIM id: OMIM:615083
Orphanet id: Orphanet:466667
All associated enzymes in DAR:
AKT1
ALOX12
BUB1
EPHA3
NRAS
RAD54B
RET
BRAF
WRN
MTHFD1
EP300
SRC
PTPRJ
MT-CO1
PTPN12
BUB1B
PIK3CA
FGFR3
EP300 |
Q09472 |
2.3.1.-
2.3.1.48
|
R-HSA-9617629
R-HSA-9617629
Reactome Name: Regulation of FOXO transcriptional activity by acetylation
See in Reactome
R-HSA-210744
R-HSA-210744
Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
See in Reactome
R-HSA-5689901
R-HSA-6804760
R-HSA-6804760
Reactome Name: Regulation of TP53 Activity through Methylation
See in Reactome
R-HSA-8939243
R-HSA-8939243
Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
See in Reactome
R-HSA-381340
R-HSA-381340
Reactome Name: Transcriptional regulation of white adipocyte differentiation
See in Reactome
R-HSA-9616222
R-HSA-9616222
Reactome Name: Transcriptional regulation of granulopoiesis
See in Reactome
R-HSA-9013695
R-HSA-9013695
Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-6782135
R-HSA-6782210
R-HSA-6782210
Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER
See in Reactome
R-HSA-8941856
R-HSA-8941856
Reactome Name: RUNX3 regulates NOTCH signaling
See in Reactome
R-HSA-8941858
R-HSA-8941858
Reactome Name: Regulation of RUNX3 expression and activity
See in Reactome
R-HSA-6804114
R-HSA-6804114
Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
See in Reactome
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-918233
R-HSA-918233
Reactome Name: TRAF3-dependent IRF activation pathway
See in Reactome
R-HSA-6781827
R-HSA-6781827
Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
See in Reactome
R-HSA-156711
R-HSA-156711
Reactome Name: Polo-like kinase mediated events
See in Reactome
R-HSA-5250924
R-HSA-5250924
Reactome Name: B-WICH complex positively regulates rRNA expression
See in Reactome
R-HSA-6781823
R-HSA-6781823
Reactome Name: Formation of TC-NER Pre-Incision Complex
See in Reactome
R-HSA-9013508
R-HSA-9013508
Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-3214847
R-HSA-3371568
R-HSA-8866907
R-HSA-8866907
Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors
See in Reactome
R-HSA-9614657
R-HSA-9614657
Reactome Name: FOXO-mediated transcription of cell death genes
See in Reactome
R-HSA-9701898
R-HSA-9701898
Reactome Name: STAT3 nuclear events downstream of ALK signaling
See in Reactome
R-HSA-933541
R-HSA-1234158
R-HSA-1234158
Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor
See in Reactome
R-HSA-1368082
R-HSA-1368082
Reactome Name: RORA activates gene expression
See in Reactome
R-HSA-5617472
R-HSA-5617472
Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis
See in Reactome
R-HSA-3899300
R-HSA-3899300
Reactome Name: SUMOylation of transcription cofactors
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8936459
R-HSA-8936459
Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-2197563
R-HSA-2197563
Reactome Name: NOTCH2 intracellular domain regulates transcription
See in Reactome
R-HSA-400253
R-HSA-9707616
R-HSA-3134973
R-HSA-3134973
Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
See in Reactome
R-HSA-201722
R-HSA-201722
Reactome Name: Formation of the beta-catenin:TCF transactivating complex
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8951936
R-HSA-5621575
R-HSA-9031628
R-HSA-6811555
R-HSA-6811555
Reactome Name: PI5P Regulates TP53 Acetylation
See in Reactome
R-HSA-6804758
R-HSA-6804758
Reactome Name: Regulation of TP53 Activity through Acetylation
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-9012852
R-HSA-5633007
R-HSA-168256
R-HSA-9013694
R-HSA-168928
R-HSA-168928
Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta
See in Reactome
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-6791312
R-HSA-6791312
Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-1430728
R-HSA-8864260
R-HSA-8864260
Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-2262752
R-HSA-73894
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-2990846
R-HSA-556833
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-8953897
R-HSA-212165
R-HSA-212165
Reactome Name: Epigenetic regulation of gene expression
See in Reactome
R-HSA-5696398
R-HSA-168249
R-HSA-453274
R-HSA-392499
R-HSA-1234174
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-1980143
R-HSA-8939211
R-HSA-1834949
R-HSA-1834949
Reactome Name: Cytosolic sensors of pathogen-associated DNA
See in Reactome
R-HSA-186712
R-HSA-186712
Reactome Name: Regulation of beta-cell development
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-157118
R-HSA-187037
R-HSA-3247509
R-HSA-195721
R-HSA-1980145
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9614085
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-5688426
R-HSA-201556
R-HSA-5250913
R-HSA-5250913
Reactome Name: Positive epigenetic regulation of rRNA expression
See in Reactome
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-4839726
R-HSA-69275
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-162582
R-HSA-5619507
R-HSA-5619507
Reactome Name: Activation of HOX genes during differentiation
See in Reactome
|
Circadian Clock
Immune System
Cell Cycle
Developmental Biology
Metabolism
Gene expression (Transcription)
DNA Repair
Cellular responses to stimuli
Metabolism of proteins
Chromatin organization
Signal Transduction
|
R-HSA-6782069
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782069
Reaction Name: UVSSA:USP7 deubiquitinates ERCC6
See in Reactome
R-HSA-9760081
()
R-HSA-9760081
Reaction Name: CREBBP, EP300 acetylates NFE2L2
See in Reactome
R-HSA-9011981
(
R-HSA-9018519
)
R-HSA-9011981
Reaction Name: EP300 is recruited to MYC and BCL2 genes
See in Reactome
R-HSA-8878050
(
R-HSA-8939243
)
R-HSA-8878050
Reaction Name: HIPK2 phosphorylates RUNX1 and EP300
See in Reactome
R-HSA-9761836
()
R-HSA-9761836
Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300
See in Reactome
R-HSA-560491
(
R-HSA-381340
)
R-HSA-4396371
(
R-HSA-2122947
)
R-HSA-4396371
Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter
See in Reactome
R-HSA-9038052
(
R-HSA-9018519
)
R-HSA-9038052
Reaction Name: GREB1 binds ESR1:ESTG and co-activators
See in Reactome
R-HSA-8952101
(
R-HSA-8951936
)
R-HSA-8952101
Reaction Name: p14-ARF transcription is stimulated by RUNX proteins
See in Reactome
R-HSA-1234167
(
R-HSA-1234158
)
R-HSA-1234167
Reaction Name: Formation of HIF:CBP:p300 complex at promoters
See in Reactome
R-HSA-9617758
(
R-HSA-9617629
)
R-HSA-9038163
(
R-HSA-9018519
)
R-HSA-9038163
Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
See in Reactome
R-HSA-9016751
(
R-HSA-9013508
)
R-HSA-9016751
Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3
See in Reactome
R-HSA-6782211
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782211
Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site
See in Reactome
R-HSA-560498
(
R-HSA-381340
)
R-HSA-560498
Reaction Name: Expression of Lipoprotein lipase (LPL)
See in Reactome
R-HSA-1980065
(
R-HSA-2122947
)
R-HSA-1980065
Reaction Name: NOTCH1 stimulates HEY transcription
See in Reactome
R-HSA-9759332
()
R-HSA-9759332
Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter
See in Reactome
R-HSA-9613451
(
R-HSA-9031628
)
R-HSA-9613451
Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
See in Reactome
R-HSA-8936621
(
R-HSA-8936459
)
R-HSA-8936621
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
See in Reactome
R-HSA-5628871
(
R-HSA-6804758
)
R-HSA-5628871
Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53
See in Reactome
R-HSA-1980067
(
R-HSA-2122947
)
R-HSA-1980067
Reaction Name: NOTCH1 stimulates MYC transcription
See in Reactome
R-HSA-9620723
(
R-HSA-9031628
)
R-HSA-5250938
(
R-HSA-5250924
)
R-HSA-5250938
Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
See in Reactome
R-HSA-6782204
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782204
Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
See in Reactome
R-HSA-5617867
(
R-HSA-5617472
)
R-HSA-9761849
()
R-HSA-9761849
Reaction Name: AcK-NFE2L2-dependent P6GD gene expression
See in Reactome
R-HSA-9023884
(
R-HSA-9018519
)
R-HSA-9023884
Reaction Name: NCOA1 recruits EP300 to TGFA promoter
See in Reactome
R-HSA-8937050
(
R-HSA-8936459
)
R-HSA-8937050
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
See in Reactome
R-HSA-8952081
(
R-HSA-8951936
)
R-HSA-8952081
Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
See in Reactome
R-HSA-3662335
(
R-HSA-3214847
)
R-HSA-3662335
Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4
See in Reactome
R-HSA-1183003
(
R-HSA-381340
)
R-HSA-6804379
(
R-HSA-6804760
)
R-HSA-4088162
(
R-HSA-156711
)
R-HSA-3134883
(
R-HSA-3134973
)
R-HSA-3134883
Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300
See in Reactome
R-HSA-381309
(
R-HSA-381340
)
R-HSA-381309
Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands
See in Reactome
R-HSA-9023846
(
R-HSA-9018519
)
R-HSA-9023846
Reaction Name: Estrogen-responsive CTSD expression
See in Reactome
R-HSA-1028820
(
R-HSA-933541
)
R-HSA-1028820
Reaction Name: Formation of VAF (virus-activated factor) complex
See in Reactome
R-HSA-8878243
(
R-HSA-8941856
)
R-HSA-8878243
Reaction Name: HES1 gene transcription is inhibited by RUNX3
See in Reactome
R-HSA-9021450
(
R-HSA-9013508
)
R-HSA-9021450
Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes
See in Reactome
R-HSA-9761828
()
R-HSA-1028817
(
R-HSA-918233
)
R-HSA-1028817
Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3
See in Reactome
R-HSA-9008315
(
R-HSA-9018519
)
R-HSA-9008315
Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen
See in Reactome
R-HSA-8936628
(
R-HSA-8936459
)
R-HSA-8936628
Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9023860
(
R-HSA-9018519
)
R-HSA-9023860
Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene
See in Reactome
R-HSA-9761846
()
R-HSA-9761846
Reaction Name: NFE2L2-dependent PGD gene expression
See in Reactome
R-HSA-8936481
(
R-HSA-8936459
)
R-HSA-8936481
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
See in Reactome
R-HSA-5663264
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-6805650
(
R-HSA-6804758
)
R-HSA-6805650
Reaction Name: MTA2-NuRD complex deacetylates TP53
See in Reactome
R-HSA-5617452
(
R-HSA-5617472
)
R-HSA-5617452
Reaction Name: Retinoic acid activates HOXB1 chromatin
See in Reactome
R-HSA-4396347
(
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-4396347
Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter
See in Reactome
R-HSA-9759141
()
R-HSA-9759141
Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene
See in Reactome
R-HSA-9760125
()
R-HSA-9760125
Reaction Name: AcK-NFE2L2-dependent GCLM gene expression
See in Reactome
R-HSA-9613460
(
R-HSA-9031628
)
R-HSA-9620717
(
R-HSA-9031628
)
R-HSA-9620717
Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter
See in Reactome
R-HSA-8951951
(
R-HSA-8951936
)
R-HSA-9029561
(
R-HSA-9029569
)
R-HSA-9029561
Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter
See in Reactome
R-HSA-560473
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-9622604
(
R-HSA-9614657
)
R-HSA-9622604
Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y
See in Reactome
R-HSA-9617064
(
R-HSA-9616222
)
R-HSA-9617064
Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
See in Reactome
R-HSA-9008285
(
R-HSA-9018519
)
R-HSA-9008285
Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
See in Reactome
R-HSA-3371554
(
R-HSA-3371568
)
R-HSA-9701531
(
R-HSA-9701898
)
R-HSA-9701531
Reaction Name: p-Y705,S727 STAT3 is acetylated
See in Reactome
R-HSA-9017835
(
R-HSA-1912408
)
R-HSA-9017835
Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene
See in Reactome
R-HSA-8937097
(
R-HSA-8936459
)
R-HSA-8937097
Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-8936616
(
R-HSA-8936459
)
R-HSA-8936616
Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene
See in Reactome
R-HSA-5663246
(
R-HSA-400253
)
R-HSA-6804229
(
R-HSA-6804760
)
R-HSA-1801587
(
R-HSA-1368082;
R-HSA-1989781;
R-HSA-400253
)
R-HSA-8878056
(
R-HSA-8939243
)
R-HSA-9761812
()
R-HSA-9761812
Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
See in Reactome
R-HSA-4396382
(
R-HSA-2122947
)
R-HSA-4396382
Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes
See in Reactome
R-HSA-5617454
(
R-HSA-5617472
)
R-HSA-560510
(
R-HSA-381340
)
R-HSA-9760097
()
R-HSA-9760097
Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene
See in Reactome
R-HSA-6782004
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782004
Reaction Name: Assembly of the pre-incision complex in TC-NER
See in Reactome
R-HSA-5250930
(
R-HSA-5250924
)
R-HSA-5250930
Reaction Name: B-WICH recruits histone acetyltransferases
See in Reactome
R-HSA-8937016
(
R-HSA-8936459
)
R-HSA-8937016
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
See in Reactome
R-HSA-400342
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-6782138
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782138
Reaction Name: ERCC5 and RPA bind TC-NER site
See in Reactome
R-HSA-5617859
(
R-HSA-5617472
)
R-HSA-5617859
Reaction Name: Retinoic acid activates HOXB4 chromatin
See in Reactome
R-HSA-8952058
(
R-HSA-8951936
)
R-HSA-8952058
Reaction Name: CCND1 binds RUNX3 and displaces EP300
See in Reactome
R-HSA-1980047
(
R-HSA-210744;
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-1980047
Reaction Name: NOTCH1 stimulates HES1 transcription
See in Reactome
R-HSA-1235037
(
R-HSA-1234158
)
R-HSA-8878237
(
R-HSA-8941856
)
R-HSA-8878237
Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter
See in Reactome
R-HSA-9622579
(
R-HSA-9614657
)
R-HSA-9622579
Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter
See in Reactome
R-HSA-9620515
(
R-HSA-9617629
)
R-HSA-9620515
Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress
See in Reactome
R-HSA-933536
(
R-HSA-933541
)
R-HSA-933536
Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300
See in Reactome
R-HSA-9760128
()
R-HSA-9760128
Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression
See in Reactome
R-HSA-9617683
(
R-HSA-9617629
)
R-HSA-9617683
Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4
See in Reactome
R-HSA-1912415
(
R-HSA-1912408
)
R-HSA-1028812
(
R-HSA-918233
)
R-HSA-5693644
(
R-HSA-5617472
)
R-HSA-5693644
Reaction Name: HOXB1 maintains activation of HOXB1 chromatin
See in Reactome
R-HSA-9760082
()
R-HSA-1912394
(
R-HSA-2122947
)
R-HSA-1912394
Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML
See in Reactome
R-HSA-560493
(
R-HSA-381340
)
R-HSA-5617862
(
R-HSA-5617472
)
R-HSA-5617862
Reaction Name: Retinoic acid activates HOXA4 chromatin
See in Reactome
R-HSA-560517
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-560517
Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT)
See in Reactome
R-HSA-1912393
(
R-HSA-2122947
)
R-HSA-1912393
Reaction Name: MAML in complex with NICD1 recruits CDK8
See in Reactome
R-HSA-8935731
(
R-HSA-8936459
)
R-HSA-8935731
Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-6782208
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782208
Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
See in Reactome
R-HSA-5663293
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-1028819
(
R-HSA-933541
)
R-HSA-1028819
Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes
See in Reactome
R-HSA-5660666
(
R-HSA-5621575
)
R-HSA-5660666
Reaction Name: CBP and p300 binds NF-kB complex
See in Reactome
R-HSA-1912416
(
R-HSA-1912408
)
R-HSA-1912391
(
R-HSA-2122947
)
R-HSA-1912391
Reaction Name: NICD1 is phosphorylated by CDK8
See in Reactome
R-HSA-9761815
()
R-HSA-9761815
Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene
See in Reactome
R-HSA-549475
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-9760122
()
R-HSA-9760122
Reaction Name: AcK-NFE2L2-dependent GCLC gene expression
See in Reactome
R-HSA-6782227
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782227
Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER
See in Reactome
R-HSA-6811508
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-6811508
Reaction Name: ING2-bound EP300 acetylates TP53
See in Reactome
R-HSA-1235035
(
R-HSA-1234158
)
R-HSA-1235035
Reaction Name: Expression of Carbonic Anhydrase IX (CA9)
See in Reactome
R-HSA-9021451
(
R-HSA-9013508
)
R-HSA-9021451
Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter
See in Reactome
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9023840
(
R-HSA-9018519
)
R-HSA-9023840
Reaction Name: HATs and coactivators are recruited to the CTSD gene
See in Reactome
R-HSA-6811479
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-5617877
(
R-HSA-5617472
)
R-HSA-8864307
(
R-HSA-8866907
)
R-HSA-8864307
Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
See in Reactome
R-HSA-1028815
(
R-HSA-918233
)
R-HSA-1028815
Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta
See in Reactome
R-HSA-6804383
(
R-HSA-6804760
)
R-HSA-6782234
(
R-HSA-6781827
)
R-HSA-6782234
Reaction Name: Recovery of RNA synthesis after TC-NER
See in Reactome
R-HSA-9011975
(
R-HSA-9018519
)
R-HSA-9011975
Reaction Name: Estrogen-responsive MYC gene expression
See in Reactome
R-HSA-8878220
(
R-HSA-8941856
)
R-HSA-8878220
Reaction Name: RUNX3 binds the NOTCH1 coactivator complex
See in Reactome
R-HSA-2976551
(
R-HSA-2197563
)
R-HSA-2976551
Reaction Name: NOTCH2 stimulates GZMB transcription
See in Reactome
R-HSA-1368081
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-5617431
(
R-HSA-5617472
)
R-HSA-5617431
Reaction Name: Retinoic acid activates HOXA1 chromatin
See in Reactome
R-HSA-1980078
(
R-HSA-2122947
)
R-HSA-1980078
Reaction Name: NOTCH1 stimulates HES5 transcription
See in Reactome
R-HSA-4396379
(
R-HSA-2122947
)
R-HSA-4396379
Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter
See in Reactome
R-HSA-3215152
(
R-HSA-6804114
)
R-HSA-3215152
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
See in Reactome
R-HSA-4088152
(
R-HSA-156711
)
R-HSA-4088152
Reaction Name: FOXM1 stimulates CDC25A transcription
See in Reactome
R-HSA-9009371
(
R-HSA-9018519
)
R-HSA-9009371
Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter
See in Reactome
R-HSA-9023859
(
R-HSA-9018519
)
R-HSA-9023859
Reaction Name: Estrogen-responsive TFF1 gene expression
See in Reactome
R-HSA-1368087
(
R-HSA-400253
)
R-HSA-1368087
Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene
See in Reactome
R-HSA-1368065
(
R-HSA-1989781;
R-HSA-400253;
R-HSA-9707616
)
R-HSA-1183058
(
R-HSA-381340
)
R-HSA-9622572
(
R-HSA-9614657
)
R-HSA-9622572
Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
See in Reactome
R-HSA-3899291
(
R-HSA-3899300
)
R-HSA-3899291
Reaction Name: SUMOylation of EP300 with SUMO1
See in Reactome
R-HSA-9634433
(
R-HSA-9616222
)
R-HSA-9634433
Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid
See in Reactome
R-HSA-9605057
(
R-HSA-9029569
)
R-HSA-9605057
Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3
See in Reactome
R-HSA-5617471
(
R-HSA-5617472
)
R-HSA-9761841
()
R-HSA-9761841
Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression
See in Reactome
R-HSA-5691381
(
R-HSA-5689901
)
R-HSA-5691381
Reaction Name: MYSM1 deubiquitinates Histone H2A
See in Reactome
R-HSA-5617874
(
R-HSA-5617472
)
R-HSA-9760099
()
R-HSA-9760099
Reaction Name: AcK-NFE2L2 binds the GCLC gene
See in Reactome
R-HSA-9018499
(
R-HSA-9018519
)
R-HSA-9018499
Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter
See in Reactome
R-HSA-9760103
()
R-HSA-9760103
Reaction Name: AcK-NFE2L2 binds the GCLM gene
See in Reactome
R-HSA-560472
(
R-HSA-381340
)
R-HSA-560472
Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
See in Reactome
R-HSA-6782131
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782131
Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-8935740
(
R-HSA-8936459
)
R-HSA-8935740
Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene
See in Reactome
R-HSA-9009378
(
R-HSA-9018519
)
R-HSA-9009378
Reaction Name: Estrogen-responsive CCND1 gene expression
See in Reactome
R-HSA-8952419
(
R-HSA-8941858
)
R-HSA-6782224
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782224
Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER
See in Reactome
R-HSA-8936979
(
R-HSA-8936459
)
R-HSA-8936979
Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene
See in Reactome
R-HSA-1235070
(
R-HSA-1234158
)
R-HSA-1235070
Reaction Name: Expression of Erythropoietin (EPO)
See in Reactome
R-HSA-5660660
(
R-HSA-5621575
)
R-HSA-3215144
(
R-HSA-6804114
)
R-HSA-3215144
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription
See in Reactome
R-HSA-8951966
(
R-HSA-8951936
)
R-HSA-9008271
(
R-HSA-9018519
)
R-HSA-9008271
Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
See in Reactome
R-HSA-9011941
(
R-HSA-9018519
)
R-HSA-9011941
Reaction Name: Estrogen-responsive BCL2 gene expression
See in Reactome
R-HSA-2976563
(
R-HSA-2197563
)
R-HSA-2976563
Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
See in Reactome
R-HSA-5663273
(
R-HSA-400253
)
R-HSA-5663273
Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene
See in Reactome
R-HSA-9604499
(
R-HSA-933541
)
R-HSA-9604499
Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300
See in Reactome
R-HSA-9604664
(
R-HSA-9013695
)
R-HSA-9604664
Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
See in Reactome
R-HSA-6782141
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782141
Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
See in Reactome
R-HSA-5617896
(
R-HSA-5617472
)
R-HSA-5617896
Reaction Name: Retinoic acid activates HOXD4 chromatin
See in Reactome
R-HSA-8937037
(
R-HSA-8936459
)
R-HSA-8937037
Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene
See in Reactome
R-HSA-9759364
()
R-HSA-9759364
Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression
See in Reactome
R-HSA-9617735
(
R-HSA-9617629
)
R-HSA-9617735
Reaction Name: TXN disrupts FOXO4 complex with EP300
See in Reactome
R-HSA-3322427
(
R-HSA-201722
)
R-HSA-3322427
Reaction Name: Beta-catenin recruits CBP/p300
See in Reactome
R-HSA-9018497
(
R-HSA-9018519
)
R-HSA-9018497
Reaction Name: Estrogen-responsive TFF3 gene expression
See in Reactome
R-HSA-8936995
(
R-HSA-8936459
)
R-HSA-8936995
Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9684118
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-9684118
Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-6804242
(
R-HSA-6804760
)
R-HSA-6804242
Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5
See in Reactome
R-HSA-9759186
()
R-HSA-9759186
Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression
See in Reactome
R-HSA-3222093
(
R-HSA-6804758
)
|
MONDO:0005611 |
EP300 |
Q09472 |
2.3.1.-
2.3.1.48
|
R-HSA-9617629
R-HSA-9617629
Reactome Name: Regulation of FOXO transcriptional activity by acetylation
See in Reactome
R-HSA-210744
R-HSA-210744
Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
See in Reactome
R-HSA-5689901
R-HSA-6804760
R-HSA-6804760
Reactome Name: Regulation of TP53 Activity through Methylation
See in Reactome
R-HSA-8939243
R-HSA-8939243
Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
See in Reactome
R-HSA-381340
R-HSA-381340
Reactome Name: Transcriptional regulation of white adipocyte differentiation
See in Reactome
R-HSA-9616222
R-HSA-9616222
Reactome Name: Transcriptional regulation of granulopoiesis
See in Reactome
R-HSA-9013695
R-HSA-9013695
Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-6782135
R-HSA-6782210
R-HSA-6782210
Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER
See in Reactome
R-HSA-8941856
R-HSA-8941856
Reactome Name: RUNX3 regulates NOTCH signaling
See in Reactome
R-HSA-8941858
R-HSA-8941858
Reactome Name: Regulation of RUNX3 expression and activity
See in Reactome
R-HSA-6804114
R-HSA-6804114
Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
See in Reactome
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-918233
R-HSA-918233
Reactome Name: TRAF3-dependent IRF activation pathway
See in Reactome
R-HSA-6781827
R-HSA-6781827
Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
See in Reactome
R-HSA-156711
R-HSA-156711
Reactome Name: Polo-like kinase mediated events
See in Reactome
R-HSA-5250924
R-HSA-5250924
Reactome Name: B-WICH complex positively regulates rRNA expression
See in Reactome
R-HSA-6781823
R-HSA-6781823
Reactome Name: Formation of TC-NER Pre-Incision Complex
See in Reactome
R-HSA-9013508
R-HSA-9013508
Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-3214847
R-HSA-3371568
R-HSA-8866907
R-HSA-8866907
Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors
See in Reactome
R-HSA-9614657
R-HSA-9614657
Reactome Name: FOXO-mediated transcription of cell death genes
See in Reactome
R-HSA-9701898
R-HSA-9701898
Reactome Name: STAT3 nuclear events downstream of ALK signaling
See in Reactome
R-HSA-933541
R-HSA-1234158
R-HSA-1234158
Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor
See in Reactome
R-HSA-1368082
R-HSA-1368082
Reactome Name: RORA activates gene expression
See in Reactome
R-HSA-5617472
R-HSA-5617472
Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis
See in Reactome
R-HSA-3899300
R-HSA-3899300
Reactome Name: SUMOylation of transcription cofactors
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8936459
R-HSA-8936459
Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-2197563
R-HSA-2197563
Reactome Name: NOTCH2 intracellular domain regulates transcription
See in Reactome
R-HSA-400253
R-HSA-9707616
R-HSA-3134973
R-HSA-3134973
Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
See in Reactome
R-HSA-201722
R-HSA-201722
Reactome Name: Formation of the beta-catenin:TCF transactivating complex
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8951936
R-HSA-5621575
R-HSA-9031628
R-HSA-6811555
R-HSA-6811555
Reactome Name: PI5P Regulates TP53 Acetylation
See in Reactome
R-HSA-6804758
R-HSA-6804758
Reactome Name: Regulation of TP53 Activity through Acetylation
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-9012852
R-HSA-5633007
R-HSA-168256
R-HSA-9013694
R-HSA-168928
R-HSA-168928
Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta
See in Reactome
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-6791312
R-HSA-6791312
Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-1430728
R-HSA-8864260
R-HSA-8864260
Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-2262752
R-HSA-73894
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-2990846
R-HSA-556833
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-8953897
R-HSA-212165
R-HSA-212165
Reactome Name: Epigenetic regulation of gene expression
See in Reactome
R-HSA-5696398
R-HSA-168249
R-HSA-453274
R-HSA-392499
R-HSA-1234174
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-1980143
R-HSA-8939211
R-HSA-1834949
R-HSA-1834949
Reactome Name: Cytosolic sensors of pathogen-associated DNA
See in Reactome
R-HSA-186712
R-HSA-186712
Reactome Name: Regulation of beta-cell development
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-157118
R-HSA-187037
R-HSA-3247509
R-HSA-195721
R-HSA-1980145
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9614085
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-5688426
R-HSA-201556
R-HSA-5250913
R-HSA-5250913
Reactome Name: Positive epigenetic regulation of rRNA expression
See in Reactome
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-4839726
R-HSA-69275
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-162582
R-HSA-5619507
R-HSA-5619507
Reactome Name: Activation of HOX genes during differentiation
See in Reactome
|
Circadian Clock
Immune System
Cell Cycle
Developmental Biology
Metabolism
Gene expression (Transcription)
DNA Repair
Cellular responses to stimuli
Metabolism of proteins
Chromatin organization
Signal Transduction
|
R-HSA-6782069
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782069
Reaction Name: UVSSA:USP7 deubiquitinates ERCC6
See in Reactome
R-HSA-9760081
()
R-HSA-9760081
Reaction Name: CREBBP, EP300 acetylates NFE2L2
See in Reactome
R-HSA-9011981
(
R-HSA-9018519
)
R-HSA-9011981
Reaction Name: EP300 is recruited to MYC and BCL2 genes
See in Reactome
R-HSA-8878050
(
R-HSA-8939243
)
R-HSA-8878050
Reaction Name: HIPK2 phosphorylates RUNX1 and EP300
See in Reactome
R-HSA-9761836
()
R-HSA-9761836
Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300
See in Reactome
R-HSA-560491
(
R-HSA-381340
)
R-HSA-4396371
(
R-HSA-2122947
)
R-HSA-4396371
Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter
See in Reactome
R-HSA-9038052
(
R-HSA-9018519
)
R-HSA-9038052
Reaction Name: GREB1 binds ESR1:ESTG and co-activators
See in Reactome
R-HSA-8952101
(
R-HSA-8951936
)
R-HSA-8952101
Reaction Name: p14-ARF transcription is stimulated by RUNX proteins
See in Reactome
R-HSA-1234167
(
R-HSA-1234158
)
R-HSA-1234167
Reaction Name: Formation of HIF:CBP:p300 complex at promoters
See in Reactome
R-HSA-9617758
(
R-HSA-9617629
)
R-HSA-9038163
(
R-HSA-9018519
)
R-HSA-9038163
Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
See in Reactome
R-HSA-9016751
(
R-HSA-9013508
)
R-HSA-9016751
Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3
See in Reactome
R-HSA-6782211
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782211
Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site
See in Reactome
R-HSA-560498
(
R-HSA-381340
)
R-HSA-560498
Reaction Name: Expression of Lipoprotein lipase (LPL)
See in Reactome
R-HSA-1980065
(
R-HSA-2122947
)
R-HSA-1980065
Reaction Name: NOTCH1 stimulates HEY transcription
See in Reactome
R-HSA-9759332
()
R-HSA-9759332
Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter
See in Reactome
R-HSA-9613451
(
R-HSA-9031628
)
R-HSA-9613451
Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
See in Reactome
R-HSA-8936621
(
R-HSA-8936459
)
R-HSA-8936621
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
See in Reactome
R-HSA-5628871
(
R-HSA-6804758
)
R-HSA-5628871
Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53
See in Reactome
R-HSA-1980067
(
R-HSA-2122947
)
R-HSA-1980067
Reaction Name: NOTCH1 stimulates MYC transcription
See in Reactome
R-HSA-9620723
(
R-HSA-9031628
)
R-HSA-5250938
(
R-HSA-5250924
)
R-HSA-5250938
Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
See in Reactome
R-HSA-6782204
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782204
Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
See in Reactome
R-HSA-5617867
(
R-HSA-5617472
)
R-HSA-9761849
()
R-HSA-9761849
Reaction Name: AcK-NFE2L2-dependent P6GD gene expression
See in Reactome
R-HSA-9023884
(
R-HSA-9018519
)
R-HSA-9023884
Reaction Name: NCOA1 recruits EP300 to TGFA promoter
See in Reactome
R-HSA-8937050
(
R-HSA-8936459
)
R-HSA-8937050
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
See in Reactome
R-HSA-8952081
(
R-HSA-8951936
)
R-HSA-8952081
Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
See in Reactome
R-HSA-3662335
(
R-HSA-3214847
)
R-HSA-3662335
Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4
See in Reactome
R-HSA-1183003
(
R-HSA-381340
)
R-HSA-6804379
(
R-HSA-6804760
)
R-HSA-4088162
(
R-HSA-156711
)
R-HSA-3134883
(
R-HSA-3134973
)
R-HSA-3134883
Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300
See in Reactome
R-HSA-381309
(
R-HSA-381340
)
R-HSA-381309
Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands
See in Reactome
R-HSA-9023846
(
R-HSA-9018519
)
R-HSA-9023846
Reaction Name: Estrogen-responsive CTSD expression
See in Reactome
R-HSA-1028820
(
R-HSA-933541
)
R-HSA-1028820
Reaction Name: Formation of VAF (virus-activated factor) complex
See in Reactome
R-HSA-8878243
(
R-HSA-8941856
)
R-HSA-8878243
Reaction Name: HES1 gene transcription is inhibited by RUNX3
See in Reactome
R-HSA-9021450
(
R-HSA-9013508
)
R-HSA-9021450
Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes
See in Reactome
R-HSA-9761828
()
R-HSA-1028817
(
R-HSA-918233
)
R-HSA-1028817
Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3
See in Reactome
R-HSA-9008315
(
R-HSA-9018519
)
R-HSA-9008315
Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen
See in Reactome
R-HSA-8936628
(
R-HSA-8936459
)
R-HSA-8936628
Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9023860
(
R-HSA-9018519
)
R-HSA-9023860
Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene
See in Reactome
R-HSA-9761846
()
R-HSA-9761846
Reaction Name: NFE2L2-dependent PGD gene expression
See in Reactome
R-HSA-8936481
(
R-HSA-8936459
)
R-HSA-8936481
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
See in Reactome
R-HSA-5663264
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-6805650
(
R-HSA-6804758
)
R-HSA-6805650
Reaction Name: MTA2-NuRD complex deacetylates TP53
See in Reactome
R-HSA-5617452
(
R-HSA-5617472
)
R-HSA-5617452
Reaction Name: Retinoic acid activates HOXB1 chromatin
See in Reactome
R-HSA-4396347
(
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-4396347
Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter
See in Reactome
R-HSA-9759141
()
R-HSA-9759141
Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene
See in Reactome
R-HSA-9760125
()
R-HSA-9760125
Reaction Name: AcK-NFE2L2-dependent GCLM gene expression
See in Reactome
R-HSA-9613460
(
R-HSA-9031628
)
R-HSA-9620717
(
R-HSA-9031628
)
R-HSA-9620717
Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter
See in Reactome
R-HSA-8951951
(
R-HSA-8951936
)
R-HSA-9029561
(
R-HSA-9029569
)
R-HSA-9029561
Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter
See in Reactome
R-HSA-560473
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-9622604
(
R-HSA-9614657
)
R-HSA-9622604
Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y
See in Reactome
R-HSA-9617064
(
R-HSA-9616222
)
R-HSA-9617064
Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
See in Reactome
R-HSA-9008285
(
R-HSA-9018519
)
R-HSA-9008285
Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
See in Reactome
R-HSA-3371554
(
R-HSA-3371568
)
R-HSA-9701531
(
R-HSA-9701898
)
R-HSA-9701531
Reaction Name: p-Y705,S727 STAT3 is acetylated
See in Reactome
R-HSA-9017835
(
R-HSA-1912408
)
R-HSA-9017835
Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene
See in Reactome
R-HSA-8937097
(
R-HSA-8936459
)
R-HSA-8937097
Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-8936616
(
R-HSA-8936459
)
R-HSA-8936616
Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene
See in Reactome
R-HSA-5663246
(
R-HSA-400253
)
R-HSA-6804229
(
R-HSA-6804760
)
R-HSA-1801587
(
R-HSA-1368082;
R-HSA-1989781;
R-HSA-400253
)
R-HSA-8878056
(
R-HSA-8939243
)
R-HSA-9761812
()
R-HSA-9761812
Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
See in Reactome
R-HSA-4396382
(
R-HSA-2122947
)
R-HSA-4396382
Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes
See in Reactome
R-HSA-5617454
(
R-HSA-5617472
)
R-HSA-560510
(
R-HSA-381340
)
R-HSA-9760097
()
R-HSA-9760097
Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene
See in Reactome
R-HSA-6782004
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782004
Reaction Name: Assembly of the pre-incision complex in TC-NER
See in Reactome
R-HSA-5250930
(
R-HSA-5250924
)
R-HSA-5250930
Reaction Name: B-WICH recruits histone acetyltransferases
See in Reactome
R-HSA-8937016
(
R-HSA-8936459
)
R-HSA-8937016
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
See in Reactome
R-HSA-400342
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-6782138
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782138
Reaction Name: ERCC5 and RPA bind TC-NER site
See in Reactome
R-HSA-5617859
(
R-HSA-5617472
)
R-HSA-5617859
Reaction Name: Retinoic acid activates HOXB4 chromatin
See in Reactome
R-HSA-8952058
(
R-HSA-8951936
)
R-HSA-8952058
Reaction Name: CCND1 binds RUNX3 and displaces EP300
See in Reactome
R-HSA-1980047
(
R-HSA-210744;
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-1980047
Reaction Name: NOTCH1 stimulates HES1 transcription
See in Reactome
R-HSA-1235037
(
R-HSA-1234158
)
R-HSA-8878237
(
R-HSA-8941856
)
R-HSA-8878237
Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter
See in Reactome
R-HSA-9622579
(
R-HSA-9614657
)
R-HSA-9622579
Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter
See in Reactome
R-HSA-9620515
(
R-HSA-9617629
)
R-HSA-9620515
Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress
See in Reactome
R-HSA-933536
(
R-HSA-933541
)
R-HSA-933536
Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300
See in Reactome
R-HSA-9760128
()
R-HSA-9760128
Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression
See in Reactome
R-HSA-9617683
(
R-HSA-9617629
)
R-HSA-9617683
Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4
See in Reactome
R-HSA-1912415
(
R-HSA-1912408
)
R-HSA-1028812
(
R-HSA-918233
)
R-HSA-5693644
(
R-HSA-5617472
)
R-HSA-5693644
Reaction Name: HOXB1 maintains activation of HOXB1 chromatin
See in Reactome
R-HSA-9760082
()
R-HSA-1912394
(
R-HSA-2122947
)
R-HSA-1912394
Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML
See in Reactome
R-HSA-560493
(
R-HSA-381340
)
R-HSA-5617862
(
R-HSA-5617472
)
R-HSA-5617862
Reaction Name: Retinoic acid activates HOXA4 chromatin
See in Reactome
R-HSA-560517
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-560517
Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT)
See in Reactome
R-HSA-1912393
(
R-HSA-2122947
)
R-HSA-1912393
Reaction Name: MAML in complex with NICD1 recruits CDK8
See in Reactome
R-HSA-8935731
(
R-HSA-8936459
)
R-HSA-8935731
Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-6782208
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782208
Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
See in Reactome
R-HSA-5663293
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-1028819
(
R-HSA-933541
)
R-HSA-1028819
Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes
See in Reactome
R-HSA-5660666
(
R-HSA-5621575
)
R-HSA-5660666
Reaction Name: CBP and p300 binds NF-kB complex
See in Reactome
R-HSA-1912416
(
R-HSA-1912408
)
R-HSA-1912391
(
R-HSA-2122947
)
R-HSA-1912391
Reaction Name: NICD1 is phosphorylated by CDK8
See in Reactome
R-HSA-9761815
()
R-HSA-9761815
Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene
See in Reactome
R-HSA-549475
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-9760122
()
R-HSA-9760122
Reaction Name: AcK-NFE2L2-dependent GCLC gene expression
See in Reactome
R-HSA-6782227
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782227
Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER
See in Reactome
R-HSA-6811508
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-6811508
Reaction Name: ING2-bound EP300 acetylates TP53
See in Reactome
R-HSA-1235035
(
R-HSA-1234158
)
R-HSA-1235035
Reaction Name: Expression of Carbonic Anhydrase IX (CA9)
See in Reactome
R-HSA-9021451
(
R-HSA-9013508
)
R-HSA-9021451
Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter
See in Reactome
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9023840
(
R-HSA-9018519
)
R-HSA-9023840
Reaction Name: HATs and coactivators are recruited to the CTSD gene
See in Reactome
R-HSA-6811479
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-5617877
(
R-HSA-5617472
)
R-HSA-8864307
(
R-HSA-8866907
)
R-HSA-8864307
Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
See in Reactome
R-HSA-1028815
(
R-HSA-918233
)
R-HSA-1028815
Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta
See in Reactome
R-HSA-6804383
(
R-HSA-6804760
)
R-HSA-6782234
(
R-HSA-6781827
)
R-HSA-6782234
Reaction Name: Recovery of RNA synthesis after TC-NER
See in Reactome
R-HSA-9011975
(
R-HSA-9018519
)
R-HSA-9011975
Reaction Name: Estrogen-responsive MYC gene expression
See in Reactome
R-HSA-8878220
(
R-HSA-8941856
)
R-HSA-8878220
Reaction Name: RUNX3 binds the NOTCH1 coactivator complex
See in Reactome
R-HSA-2976551
(
R-HSA-2197563
)
R-HSA-2976551
Reaction Name: NOTCH2 stimulates GZMB transcription
See in Reactome
R-HSA-1368081
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-5617431
(
R-HSA-5617472
)
R-HSA-5617431
Reaction Name: Retinoic acid activates HOXA1 chromatin
See in Reactome
R-HSA-1980078
(
R-HSA-2122947
)
R-HSA-1980078
Reaction Name: NOTCH1 stimulates HES5 transcription
See in Reactome
R-HSA-4396379
(
R-HSA-2122947
)
R-HSA-4396379
Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter
See in Reactome
R-HSA-3215152
(
R-HSA-6804114
)
R-HSA-3215152
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
See in Reactome
R-HSA-4088152
(
R-HSA-156711
)
R-HSA-4088152
Reaction Name: FOXM1 stimulates CDC25A transcription
See in Reactome
R-HSA-9009371
(
R-HSA-9018519
)
R-HSA-9009371
Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter
See in Reactome
R-HSA-9023859
(
R-HSA-9018519
)
R-HSA-9023859
Reaction Name: Estrogen-responsive TFF1 gene expression
See in Reactome
R-HSA-1368087
(
R-HSA-400253
)
R-HSA-1368087
Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene
See in Reactome
R-HSA-1368065
(
R-HSA-1989781;
R-HSA-400253;
R-HSA-9707616
)
R-HSA-1183058
(
R-HSA-381340
)
R-HSA-9622572
(
R-HSA-9614657
)
R-HSA-9622572
Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
See in Reactome
R-HSA-3899291
(
R-HSA-3899300
)
R-HSA-3899291
Reaction Name: SUMOylation of EP300 with SUMO1
See in Reactome
R-HSA-9634433
(
R-HSA-9616222
)
R-HSA-9634433
Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid
See in Reactome
R-HSA-9605057
(
R-HSA-9029569
)
R-HSA-9605057
Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3
See in Reactome
R-HSA-5617471
(
R-HSA-5617472
)
R-HSA-9761841
()
R-HSA-9761841
Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression
See in Reactome
R-HSA-5691381
(
R-HSA-5689901
)
R-HSA-5691381
Reaction Name: MYSM1 deubiquitinates Histone H2A
See in Reactome
R-HSA-5617874
(
R-HSA-5617472
)
R-HSA-9760099
()
R-HSA-9760099
Reaction Name: AcK-NFE2L2 binds the GCLC gene
See in Reactome
R-HSA-9018499
(
R-HSA-9018519
)
R-HSA-9018499
Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter
See in Reactome
R-HSA-9760103
()
R-HSA-9760103
Reaction Name: AcK-NFE2L2 binds the GCLM gene
See in Reactome
R-HSA-560472
(
R-HSA-381340
)
R-HSA-560472
Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
See in Reactome
R-HSA-6782131
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782131
Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-8935740
(
R-HSA-8936459
)
R-HSA-8935740
Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene
See in Reactome
R-HSA-9009378
(
R-HSA-9018519
)
R-HSA-9009378
Reaction Name: Estrogen-responsive CCND1 gene expression
See in Reactome
R-HSA-8952419
(
R-HSA-8941858
)
R-HSA-6782224
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782224
Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER
See in Reactome
R-HSA-8936979
(
R-HSA-8936459
)
R-HSA-8936979
Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene
See in Reactome
R-HSA-1235070
(
R-HSA-1234158
)
R-HSA-1235070
Reaction Name: Expression of Erythropoietin (EPO)
See in Reactome
R-HSA-5660660
(
R-HSA-5621575
)
R-HSA-3215144
(
R-HSA-6804114
)
R-HSA-3215144
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription
See in Reactome
R-HSA-8951966
(
R-HSA-8951936
)
R-HSA-9008271
(
R-HSA-9018519
)
R-HSA-9008271
Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
See in Reactome
R-HSA-9011941
(
R-HSA-9018519
)
R-HSA-9011941
Reaction Name: Estrogen-responsive BCL2 gene expression
See in Reactome
R-HSA-2976563
(
R-HSA-2197563
)
R-HSA-2976563
Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
See in Reactome
R-HSA-5663273
(
R-HSA-400253
)
R-HSA-5663273
Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene
See in Reactome
R-HSA-9604499
(
R-HSA-933541
)
R-HSA-9604499
Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300
See in Reactome
R-HSA-9604664
(
R-HSA-9013695
)
R-HSA-9604664
Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
See in Reactome
R-HSA-6782141
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782141
Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
See in Reactome
R-HSA-5617896
(
R-HSA-5617472
)
R-HSA-5617896
Reaction Name: Retinoic acid activates HOXD4 chromatin
See in Reactome
R-HSA-8937037
(
R-HSA-8936459
)
R-HSA-8937037
Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene
See in Reactome
R-HSA-9759364
()
R-HSA-9759364
Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression
See in Reactome
R-HSA-9617735
(
R-HSA-9617629
)
R-HSA-9617735
Reaction Name: TXN disrupts FOXO4 complex with EP300
See in Reactome
R-HSA-3322427
(
R-HSA-201722
)
R-HSA-3322427
Reaction Name: Beta-catenin recruits CBP/p300
See in Reactome
R-HSA-9018497
(
R-HSA-9018519
)
R-HSA-9018497
Reaction Name: Estrogen-responsive TFF3 gene expression
See in Reactome
R-HSA-8936995
(
R-HSA-8936459
)
R-HSA-8936995
Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9684118
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-9684118
Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-6804242
(
R-HSA-6804760
)
R-HSA-6804242
Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5
See in Reactome
R-HSA-9759186
()
R-HSA-9759186
Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression
See in Reactome
R-HSA-3222093
(
R-HSA-6804758
)
|
MONDO:0007154 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0007256 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0007265 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0007648 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0007959 |
MONDO:0007959
Disease Name: medulloblastoma
OMIM id: OMIM:155255
Orphanet id: Orphanet:616
All associated enzymes in DAR:
EP300
. The disease is also associated to other non-enzyme proteins (not in DAR).
EP300 |
Q09472 |
2.3.1.-
2.3.1.48
|
R-HSA-9617629
R-HSA-9617629
Reactome Name: Regulation of FOXO transcriptional activity by acetylation
See in Reactome
R-HSA-210744
R-HSA-210744
Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
See in Reactome
R-HSA-5689901
R-HSA-6804760
R-HSA-6804760
Reactome Name: Regulation of TP53 Activity through Methylation
See in Reactome
R-HSA-8939243
R-HSA-8939243
Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
See in Reactome
R-HSA-381340
R-HSA-381340
Reactome Name: Transcriptional regulation of white adipocyte differentiation
See in Reactome
R-HSA-9616222
R-HSA-9616222
Reactome Name: Transcriptional regulation of granulopoiesis
See in Reactome
R-HSA-9013695
R-HSA-9013695
Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-6782135
R-HSA-6782210
R-HSA-6782210
Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER
See in Reactome
R-HSA-8941856
R-HSA-8941856
Reactome Name: RUNX3 regulates NOTCH signaling
See in Reactome
R-HSA-8941858
R-HSA-8941858
Reactome Name: Regulation of RUNX3 expression and activity
See in Reactome
R-HSA-6804114
R-HSA-6804114
Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
See in Reactome
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-918233
R-HSA-918233
Reactome Name: TRAF3-dependent IRF activation pathway
See in Reactome
R-HSA-6781827
R-HSA-6781827
Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
See in Reactome
R-HSA-156711
R-HSA-156711
Reactome Name: Polo-like kinase mediated events
See in Reactome
R-HSA-5250924
R-HSA-5250924
Reactome Name: B-WICH complex positively regulates rRNA expression
See in Reactome
R-HSA-6781823
R-HSA-6781823
Reactome Name: Formation of TC-NER Pre-Incision Complex
See in Reactome
R-HSA-9013508
R-HSA-9013508
Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-3214847
R-HSA-3371568
R-HSA-8866907
R-HSA-8866907
Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors
See in Reactome
R-HSA-9614657
R-HSA-9614657
Reactome Name: FOXO-mediated transcription of cell death genes
See in Reactome
R-HSA-9701898
R-HSA-9701898
Reactome Name: STAT3 nuclear events downstream of ALK signaling
See in Reactome
R-HSA-933541
R-HSA-1234158
R-HSA-1234158
Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor
See in Reactome
R-HSA-1368082
R-HSA-1368082
Reactome Name: RORA activates gene expression
See in Reactome
R-HSA-5617472
R-HSA-5617472
Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis
See in Reactome
R-HSA-3899300
R-HSA-3899300
Reactome Name: SUMOylation of transcription cofactors
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8936459
R-HSA-8936459
Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-2197563
R-HSA-2197563
Reactome Name: NOTCH2 intracellular domain regulates transcription
See in Reactome
R-HSA-400253
R-HSA-9707616
R-HSA-3134973
R-HSA-3134973
Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
See in Reactome
R-HSA-201722
R-HSA-201722
Reactome Name: Formation of the beta-catenin:TCF transactivating complex
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8951936
R-HSA-5621575
R-HSA-9031628
R-HSA-6811555
R-HSA-6811555
Reactome Name: PI5P Regulates TP53 Acetylation
See in Reactome
R-HSA-6804758
R-HSA-6804758
Reactome Name: Regulation of TP53 Activity through Acetylation
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-9012852
R-HSA-5633007
R-HSA-168256
R-HSA-9013694
R-HSA-168928
R-HSA-168928
Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta
See in Reactome
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-6791312
R-HSA-6791312
Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-1430728
R-HSA-8864260
R-HSA-8864260
Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-2262752
R-HSA-73894
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-2990846
R-HSA-556833
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-8953897
R-HSA-212165
R-HSA-212165
Reactome Name: Epigenetic regulation of gene expression
See in Reactome
R-HSA-5696398
R-HSA-168249
R-HSA-453274
R-HSA-392499
R-HSA-1234174
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-1980143
R-HSA-8939211
R-HSA-1834949
R-HSA-1834949
Reactome Name: Cytosolic sensors of pathogen-associated DNA
See in Reactome
R-HSA-186712
R-HSA-186712
Reactome Name: Regulation of beta-cell development
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-157118
R-HSA-187037
R-HSA-3247509
R-HSA-195721
R-HSA-1980145
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9614085
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-5688426
R-HSA-201556
R-HSA-5250913
R-HSA-5250913
Reactome Name: Positive epigenetic regulation of rRNA expression
See in Reactome
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-4839726
R-HSA-69275
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-162582
R-HSA-5619507
R-HSA-5619507
Reactome Name: Activation of HOX genes during differentiation
See in Reactome
|
Circadian Clock
Immune System
Cell Cycle
Developmental Biology
Metabolism
Gene expression (Transcription)
DNA Repair
Cellular responses to stimuli
Metabolism of proteins
Chromatin organization
Signal Transduction
|
R-HSA-6782069
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782069
Reaction Name: UVSSA:USP7 deubiquitinates ERCC6
See in Reactome
R-HSA-9760081
()
R-HSA-9760081
Reaction Name: CREBBP, EP300 acetylates NFE2L2
See in Reactome
R-HSA-9011981
(
R-HSA-9018519
)
R-HSA-9011981
Reaction Name: EP300 is recruited to MYC and BCL2 genes
See in Reactome
R-HSA-8878050
(
R-HSA-8939243
)
R-HSA-8878050
Reaction Name: HIPK2 phosphorylates RUNX1 and EP300
See in Reactome
R-HSA-9761836
()
R-HSA-9761836
Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300
See in Reactome
R-HSA-560491
(
R-HSA-381340
)
R-HSA-4396371
(
R-HSA-2122947
)
R-HSA-4396371
Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter
See in Reactome
R-HSA-9038052
(
R-HSA-9018519
)
R-HSA-9038052
Reaction Name: GREB1 binds ESR1:ESTG and co-activators
See in Reactome
R-HSA-8952101
(
R-HSA-8951936
)
R-HSA-8952101
Reaction Name: p14-ARF transcription is stimulated by RUNX proteins
See in Reactome
R-HSA-1234167
(
R-HSA-1234158
)
R-HSA-1234167
Reaction Name: Formation of HIF:CBP:p300 complex at promoters
See in Reactome
R-HSA-9617758
(
R-HSA-9617629
)
R-HSA-9038163
(
R-HSA-9018519
)
R-HSA-9038163
Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
See in Reactome
R-HSA-9016751
(
R-HSA-9013508
)
R-HSA-9016751
Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3
See in Reactome
R-HSA-6782211
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782211
Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site
See in Reactome
R-HSA-560498
(
R-HSA-381340
)
R-HSA-560498
Reaction Name: Expression of Lipoprotein lipase (LPL)
See in Reactome
R-HSA-1980065
(
R-HSA-2122947
)
R-HSA-1980065
Reaction Name: NOTCH1 stimulates HEY transcription
See in Reactome
R-HSA-9759332
()
R-HSA-9759332
Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter
See in Reactome
R-HSA-9613451
(
R-HSA-9031628
)
R-HSA-9613451
Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
See in Reactome
R-HSA-8936621
(
R-HSA-8936459
)
R-HSA-8936621
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
See in Reactome
R-HSA-5628871
(
R-HSA-6804758
)
R-HSA-5628871
Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53
See in Reactome
R-HSA-1980067
(
R-HSA-2122947
)
R-HSA-1980067
Reaction Name: NOTCH1 stimulates MYC transcription
See in Reactome
R-HSA-9620723
(
R-HSA-9031628
)
R-HSA-5250938
(
R-HSA-5250924
)
R-HSA-5250938
Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
See in Reactome
R-HSA-6782204
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782204
Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
See in Reactome
R-HSA-5617867
(
R-HSA-5617472
)
R-HSA-9761849
()
R-HSA-9761849
Reaction Name: AcK-NFE2L2-dependent P6GD gene expression
See in Reactome
R-HSA-9023884
(
R-HSA-9018519
)
R-HSA-9023884
Reaction Name: NCOA1 recruits EP300 to TGFA promoter
See in Reactome
R-HSA-8937050
(
R-HSA-8936459
)
R-HSA-8937050
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
See in Reactome
R-HSA-8952081
(
R-HSA-8951936
)
R-HSA-8952081
Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
See in Reactome
R-HSA-3662335
(
R-HSA-3214847
)
R-HSA-3662335
Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4
See in Reactome
R-HSA-1183003
(
R-HSA-381340
)
R-HSA-6804379
(
R-HSA-6804760
)
R-HSA-4088162
(
R-HSA-156711
)
R-HSA-3134883
(
R-HSA-3134973
)
R-HSA-3134883
Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300
See in Reactome
R-HSA-381309
(
R-HSA-381340
)
R-HSA-381309
Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands
See in Reactome
R-HSA-9023846
(
R-HSA-9018519
)
R-HSA-9023846
Reaction Name: Estrogen-responsive CTSD expression
See in Reactome
R-HSA-1028820
(
R-HSA-933541
)
R-HSA-1028820
Reaction Name: Formation of VAF (virus-activated factor) complex
See in Reactome
R-HSA-8878243
(
R-HSA-8941856
)
R-HSA-8878243
Reaction Name: HES1 gene transcription is inhibited by RUNX3
See in Reactome
R-HSA-9021450
(
R-HSA-9013508
)
R-HSA-9021450
Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes
See in Reactome
R-HSA-9761828
()
R-HSA-1028817
(
R-HSA-918233
)
R-HSA-1028817
Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3
See in Reactome
R-HSA-9008315
(
R-HSA-9018519
)
R-HSA-9008315
Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen
See in Reactome
R-HSA-8936628
(
R-HSA-8936459
)
R-HSA-8936628
Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9023860
(
R-HSA-9018519
)
R-HSA-9023860
Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene
See in Reactome
R-HSA-9761846
()
R-HSA-9761846
Reaction Name: NFE2L2-dependent PGD gene expression
See in Reactome
R-HSA-8936481
(
R-HSA-8936459
)
R-HSA-8936481
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
See in Reactome
R-HSA-5663264
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-6805650
(
R-HSA-6804758
)
R-HSA-6805650
Reaction Name: MTA2-NuRD complex deacetylates TP53
See in Reactome
R-HSA-5617452
(
R-HSA-5617472
)
R-HSA-5617452
Reaction Name: Retinoic acid activates HOXB1 chromatin
See in Reactome
R-HSA-4396347
(
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-4396347
Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter
See in Reactome
R-HSA-9759141
()
R-HSA-9759141
Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene
See in Reactome
R-HSA-9760125
()
R-HSA-9760125
Reaction Name: AcK-NFE2L2-dependent GCLM gene expression
See in Reactome
R-HSA-9613460
(
R-HSA-9031628
)
R-HSA-9620717
(
R-HSA-9031628
)
R-HSA-9620717
Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter
See in Reactome
R-HSA-8951951
(
R-HSA-8951936
)
R-HSA-9029561
(
R-HSA-9029569
)
R-HSA-9029561
Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter
See in Reactome
R-HSA-560473
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-9622604
(
R-HSA-9614657
)
R-HSA-9622604
Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y
See in Reactome
R-HSA-9617064
(
R-HSA-9616222
)
R-HSA-9617064
Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
See in Reactome
R-HSA-9008285
(
R-HSA-9018519
)
R-HSA-9008285
Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
See in Reactome
R-HSA-3371554
(
R-HSA-3371568
)
R-HSA-9701531
(
R-HSA-9701898
)
R-HSA-9701531
Reaction Name: p-Y705,S727 STAT3 is acetylated
See in Reactome
R-HSA-9017835
(
R-HSA-1912408
)
R-HSA-9017835
Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene
See in Reactome
R-HSA-8937097
(
R-HSA-8936459
)
R-HSA-8937097
Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-8936616
(
R-HSA-8936459
)
R-HSA-8936616
Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene
See in Reactome
R-HSA-5663246
(
R-HSA-400253
)
R-HSA-6804229
(
R-HSA-6804760
)
R-HSA-1801587
(
R-HSA-1368082;
R-HSA-1989781;
R-HSA-400253
)
R-HSA-8878056
(
R-HSA-8939243
)
R-HSA-9761812
()
R-HSA-9761812
Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
See in Reactome
R-HSA-4396382
(
R-HSA-2122947
)
R-HSA-4396382
Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes
See in Reactome
R-HSA-5617454
(
R-HSA-5617472
)
R-HSA-560510
(
R-HSA-381340
)
R-HSA-9760097
()
R-HSA-9760097
Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene
See in Reactome
R-HSA-6782004
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782004
Reaction Name: Assembly of the pre-incision complex in TC-NER
See in Reactome
R-HSA-5250930
(
R-HSA-5250924
)
R-HSA-5250930
Reaction Name: B-WICH recruits histone acetyltransferases
See in Reactome
R-HSA-8937016
(
R-HSA-8936459
)
R-HSA-8937016
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
See in Reactome
R-HSA-400342
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-6782138
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782138
Reaction Name: ERCC5 and RPA bind TC-NER site
See in Reactome
R-HSA-5617859
(
R-HSA-5617472
)
R-HSA-5617859
Reaction Name: Retinoic acid activates HOXB4 chromatin
See in Reactome
R-HSA-8952058
(
R-HSA-8951936
)
R-HSA-8952058
Reaction Name: CCND1 binds RUNX3 and displaces EP300
See in Reactome
R-HSA-1980047
(
R-HSA-210744;
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-1980047
Reaction Name: NOTCH1 stimulates HES1 transcription
See in Reactome
R-HSA-1235037
(
R-HSA-1234158
)
R-HSA-8878237
(
R-HSA-8941856
)
R-HSA-8878237
Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter
See in Reactome
R-HSA-9622579
(
R-HSA-9614657
)
R-HSA-9622579
Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter
See in Reactome
R-HSA-9620515
(
R-HSA-9617629
)
R-HSA-9620515
Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress
See in Reactome
R-HSA-933536
(
R-HSA-933541
)
R-HSA-933536
Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300
See in Reactome
R-HSA-9760128
()
R-HSA-9760128
Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression
See in Reactome
R-HSA-9617683
(
R-HSA-9617629
)
R-HSA-9617683
Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4
See in Reactome
R-HSA-1912415
(
R-HSA-1912408
)
R-HSA-1028812
(
R-HSA-918233
)
R-HSA-5693644
(
R-HSA-5617472
)
R-HSA-5693644
Reaction Name: HOXB1 maintains activation of HOXB1 chromatin
See in Reactome
R-HSA-9760082
()
R-HSA-1912394
(
R-HSA-2122947
)
R-HSA-1912394
Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML
See in Reactome
R-HSA-560493
(
R-HSA-381340
)
R-HSA-5617862
(
R-HSA-5617472
)
R-HSA-5617862
Reaction Name: Retinoic acid activates HOXA4 chromatin
See in Reactome
R-HSA-560517
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-560517
Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT)
See in Reactome
R-HSA-1912393
(
R-HSA-2122947
)
R-HSA-1912393
Reaction Name: MAML in complex with NICD1 recruits CDK8
See in Reactome
R-HSA-8935731
(
R-HSA-8936459
)
R-HSA-8935731
Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-6782208
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782208
Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
See in Reactome
R-HSA-5663293
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-1028819
(
R-HSA-933541
)
R-HSA-1028819
Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes
See in Reactome
R-HSA-5660666
(
R-HSA-5621575
)
R-HSA-5660666
Reaction Name: CBP and p300 binds NF-kB complex
See in Reactome
R-HSA-1912416
(
R-HSA-1912408
)
R-HSA-1912391
(
R-HSA-2122947
)
R-HSA-1912391
Reaction Name: NICD1 is phosphorylated by CDK8
See in Reactome
R-HSA-9761815
()
R-HSA-9761815
Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene
See in Reactome
R-HSA-549475
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-9760122
()
R-HSA-9760122
Reaction Name: AcK-NFE2L2-dependent GCLC gene expression
See in Reactome
R-HSA-6782227
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782227
Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER
See in Reactome
R-HSA-6811508
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-6811508
Reaction Name: ING2-bound EP300 acetylates TP53
See in Reactome
R-HSA-1235035
(
R-HSA-1234158
)
R-HSA-1235035
Reaction Name: Expression of Carbonic Anhydrase IX (CA9)
See in Reactome
R-HSA-9021451
(
R-HSA-9013508
)
R-HSA-9021451
Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter
See in Reactome
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9023840
(
R-HSA-9018519
)
R-HSA-9023840
Reaction Name: HATs and coactivators are recruited to the CTSD gene
See in Reactome
R-HSA-6811479
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-5617877
(
R-HSA-5617472
)
R-HSA-8864307
(
R-HSA-8866907
)
R-HSA-8864307
Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
See in Reactome
R-HSA-1028815
(
R-HSA-918233
)
R-HSA-1028815
Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta
See in Reactome
R-HSA-6804383
(
R-HSA-6804760
)
R-HSA-6782234
(
R-HSA-6781827
)
R-HSA-6782234
Reaction Name: Recovery of RNA synthesis after TC-NER
See in Reactome
R-HSA-9011975
(
R-HSA-9018519
)
R-HSA-9011975
Reaction Name: Estrogen-responsive MYC gene expression
See in Reactome
R-HSA-8878220
(
R-HSA-8941856
)
R-HSA-8878220
Reaction Name: RUNX3 binds the NOTCH1 coactivator complex
See in Reactome
R-HSA-2976551
(
R-HSA-2197563
)
R-HSA-2976551
Reaction Name: NOTCH2 stimulates GZMB transcription
See in Reactome
R-HSA-1368081
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-5617431
(
R-HSA-5617472
)
R-HSA-5617431
Reaction Name: Retinoic acid activates HOXA1 chromatin
See in Reactome
R-HSA-1980078
(
R-HSA-2122947
)
R-HSA-1980078
Reaction Name: NOTCH1 stimulates HES5 transcription
See in Reactome
R-HSA-4396379
(
R-HSA-2122947
)
R-HSA-4396379
Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter
See in Reactome
R-HSA-3215152
(
R-HSA-6804114
)
R-HSA-3215152
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
See in Reactome
R-HSA-4088152
(
R-HSA-156711
)
R-HSA-4088152
Reaction Name: FOXM1 stimulates CDC25A transcription
See in Reactome
R-HSA-9009371
(
R-HSA-9018519
)
R-HSA-9009371
Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter
See in Reactome
R-HSA-9023859
(
R-HSA-9018519
)
R-HSA-9023859
Reaction Name: Estrogen-responsive TFF1 gene expression
See in Reactome
R-HSA-1368087
(
R-HSA-400253
)
R-HSA-1368087
Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene
See in Reactome
R-HSA-1368065
(
R-HSA-1989781;
R-HSA-400253;
R-HSA-9707616
)
R-HSA-1183058
(
R-HSA-381340
)
R-HSA-9622572
(
R-HSA-9614657
)
R-HSA-9622572
Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
See in Reactome
R-HSA-3899291
(
R-HSA-3899300
)
R-HSA-3899291
Reaction Name: SUMOylation of EP300 with SUMO1
See in Reactome
R-HSA-9634433
(
R-HSA-9616222
)
R-HSA-9634433
Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid
See in Reactome
R-HSA-9605057
(
R-HSA-9029569
)
R-HSA-9605057
Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3
See in Reactome
R-HSA-5617471
(
R-HSA-5617472
)
R-HSA-9761841
()
R-HSA-9761841
Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression
See in Reactome
R-HSA-5691381
(
R-HSA-5689901
)
R-HSA-5691381
Reaction Name: MYSM1 deubiquitinates Histone H2A
See in Reactome
R-HSA-5617874
(
R-HSA-5617472
)
R-HSA-9760099
()
R-HSA-9760099
Reaction Name: AcK-NFE2L2 binds the GCLC gene
See in Reactome
R-HSA-9018499
(
R-HSA-9018519
)
R-HSA-9018499
Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter
See in Reactome
R-HSA-9760103
()
R-HSA-9760103
Reaction Name: AcK-NFE2L2 binds the GCLM gene
See in Reactome
R-HSA-560472
(
R-HSA-381340
)
R-HSA-560472
Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
See in Reactome
R-HSA-6782131
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782131
Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-8935740
(
R-HSA-8936459
)
R-HSA-8935740
Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene
See in Reactome
R-HSA-9009378
(
R-HSA-9018519
)
R-HSA-9009378
Reaction Name: Estrogen-responsive CCND1 gene expression
See in Reactome
R-HSA-8952419
(
R-HSA-8941858
)
R-HSA-6782224
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782224
Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER
See in Reactome
R-HSA-8936979
(
R-HSA-8936459
)
R-HSA-8936979
Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene
See in Reactome
R-HSA-1235070
(
R-HSA-1234158
)
R-HSA-1235070
Reaction Name: Expression of Erythropoietin (EPO)
See in Reactome
R-HSA-5660660
(
R-HSA-5621575
)
R-HSA-3215144
(
R-HSA-6804114
)
R-HSA-3215144
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription
See in Reactome
R-HSA-8951966
(
R-HSA-8951936
)
R-HSA-9008271
(
R-HSA-9018519
)
R-HSA-9008271
Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
See in Reactome
R-HSA-9011941
(
R-HSA-9018519
)
R-HSA-9011941
Reaction Name: Estrogen-responsive BCL2 gene expression
See in Reactome
R-HSA-2976563
(
R-HSA-2197563
)
R-HSA-2976563
Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
See in Reactome
R-HSA-5663273
(
R-HSA-400253
)
R-HSA-5663273
Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene
See in Reactome
R-HSA-9604499
(
R-HSA-933541
)
R-HSA-9604499
Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300
See in Reactome
R-HSA-9604664
(
R-HSA-9013695
)
R-HSA-9604664
Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
See in Reactome
R-HSA-6782141
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782141
Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
See in Reactome
R-HSA-5617896
(
R-HSA-5617472
)
R-HSA-5617896
Reaction Name: Retinoic acid activates HOXD4 chromatin
See in Reactome
R-HSA-8937037
(
R-HSA-8936459
)
R-HSA-8937037
Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene
See in Reactome
R-HSA-9759364
()
R-HSA-9759364
Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression
See in Reactome
R-HSA-9617735
(
R-HSA-9617629
)
R-HSA-9617735
Reaction Name: TXN disrupts FOXO4 complex with EP300
See in Reactome
R-HSA-3322427
(
R-HSA-201722
)
R-HSA-3322427
Reaction Name: Beta-catenin recruits CBP/p300
See in Reactome
R-HSA-9018497
(
R-HSA-9018519
)
R-HSA-9018497
Reaction Name: Estrogen-responsive TFF3 gene expression
See in Reactome
R-HSA-8936995
(
R-HSA-8936459
)
R-HSA-8936995
Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9684118
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-9684118
Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-6804242
(
R-HSA-6804760
)
R-HSA-6804242
Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5
See in Reactome
R-HSA-9759186
()
R-HSA-9759186
Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression
See in Reactome
R-HSA-3222093
(
R-HSA-6804758
)
|
MONDO:0008097 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0008393 |
EP300 |
Q09472 |
2.3.1.-
2.3.1.48
|
R-HSA-9617629
R-HSA-9617629
Reactome Name: Regulation of FOXO transcriptional activity by acetylation
See in Reactome
R-HSA-210744
R-HSA-210744
Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
See in Reactome
R-HSA-5689901
R-HSA-6804760
R-HSA-6804760
Reactome Name: Regulation of TP53 Activity through Methylation
See in Reactome
R-HSA-8939243
R-HSA-8939243
Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
See in Reactome
R-HSA-381340
R-HSA-381340
Reactome Name: Transcriptional regulation of white adipocyte differentiation
See in Reactome
R-HSA-9616222
R-HSA-9616222
Reactome Name: Transcriptional regulation of granulopoiesis
See in Reactome
R-HSA-9013695
R-HSA-9013695
Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-6782135
R-HSA-6782210
R-HSA-6782210
Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER
See in Reactome
R-HSA-8941856
R-HSA-8941856
Reactome Name: RUNX3 regulates NOTCH signaling
See in Reactome
R-HSA-8941858
R-HSA-8941858
Reactome Name: Regulation of RUNX3 expression and activity
See in Reactome
R-HSA-6804114
R-HSA-6804114
Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
See in Reactome
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-918233
R-HSA-918233
Reactome Name: TRAF3-dependent IRF activation pathway
See in Reactome
R-HSA-6781827
R-HSA-6781827
Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
See in Reactome
R-HSA-156711
R-HSA-156711
Reactome Name: Polo-like kinase mediated events
See in Reactome
R-HSA-5250924
R-HSA-5250924
Reactome Name: B-WICH complex positively regulates rRNA expression
See in Reactome
R-HSA-6781823
R-HSA-6781823
Reactome Name: Formation of TC-NER Pre-Incision Complex
See in Reactome
R-HSA-9013508
R-HSA-9013508
Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-3214847
R-HSA-3371568
R-HSA-8866907
R-HSA-8866907
Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors
See in Reactome
R-HSA-9614657
R-HSA-9614657
Reactome Name: FOXO-mediated transcription of cell death genes
See in Reactome
R-HSA-9701898
R-HSA-9701898
Reactome Name: STAT3 nuclear events downstream of ALK signaling
See in Reactome
R-HSA-933541
R-HSA-1234158
R-HSA-1234158
Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor
See in Reactome
R-HSA-1368082
R-HSA-1368082
Reactome Name: RORA activates gene expression
See in Reactome
R-HSA-5617472
R-HSA-5617472
Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis
See in Reactome
R-HSA-3899300
R-HSA-3899300
Reactome Name: SUMOylation of transcription cofactors
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8936459
R-HSA-8936459
Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-2197563
R-HSA-2197563
Reactome Name: NOTCH2 intracellular domain regulates transcription
See in Reactome
R-HSA-400253
R-HSA-9707616
R-HSA-3134973
R-HSA-3134973
Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
See in Reactome
R-HSA-201722
R-HSA-201722
Reactome Name: Formation of the beta-catenin:TCF transactivating complex
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8951936
R-HSA-5621575
R-HSA-9031628
R-HSA-6811555
R-HSA-6811555
Reactome Name: PI5P Regulates TP53 Acetylation
See in Reactome
R-HSA-6804758
R-HSA-6804758
Reactome Name: Regulation of TP53 Activity through Acetylation
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-9012852
R-HSA-5633007
R-HSA-168256
R-HSA-9013694
R-HSA-168928
R-HSA-168928
Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta
See in Reactome
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-6791312
R-HSA-6791312
Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-1430728
R-HSA-8864260
R-HSA-8864260
Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-2262752
R-HSA-73894
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-2990846
R-HSA-556833
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-8953897
R-HSA-212165
R-HSA-212165
Reactome Name: Epigenetic regulation of gene expression
See in Reactome
R-HSA-5696398
R-HSA-168249
R-HSA-453274
R-HSA-392499
R-HSA-1234174
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-1980143
R-HSA-8939211
R-HSA-1834949
R-HSA-1834949
Reactome Name: Cytosolic sensors of pathogen-associated DNA
See in Reactome
R-HSA-186712
R-HSA-186712
Reactome Name: Regulation of beta-cell development
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-157118
R-HSA-187037
R-HSA-3247509
R-HSA-195721
R-HSA-1980145
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9614085
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-5688426
R-HSA-201556
R-HSA-5250913
R-HSA-5250913
Reactome Name: Positive epigenetic regulation of rRNA expression
See in Reactome
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-4839726
R-HSA-69275
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-162582
R-HSA-5619507
R-HSA-5619507
Reactome Name: Activation of HOX genes during differentiation
See in Reactome
|
Circadian Clock
Immune System
Cell Cycle
Developmental Biology
Metabolism
Gene expression (Transcription)
DNA Repair
Cellular responses to stimuli
Metabolism of proteins
Chromatin organization
Signal Transduction
|
R-HSA-6782069
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782069
Reaction Name: UVSSA:USP7 deubiquitinates ERCC6
See in Reactome
R-HSA-9760081
()
R-HSA-9760081
Reaction Name: CREBBP, EP300 acetylates NFE2L2
See in Reactome
R-HSA-9011981
(
R-HSA-9018519
)
R-HSA-9011981
Reaction Name: EP300 is recruited to MYC and BCL2 genes
See in Reactome
R-HSA-8878050
(
R-HSA-8939243
)
R-HSA-8878050
Reaction Name: HIPK2 phosphorylates RUNX1 and EP300
See in Reactome
R-HSA-9761836
()
R-HSA-9761836
Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300
See in Reactome
R-HSA-560491
(
R-HSA-381340
)
R-HSA-4396371
(
R-HSA-2122947
)
R-HSA-4396371
Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter
See in Reactome
R-HSA-9038052
(
R-HSA-9018519
)
R-HSA-9038052
Reaction Name: GREB1 binds ESR1:ESTG and co-activators
See in Reactome
R-HSA-8952101
(
R-HSA-8951936
)
R-HSA-8952101
Reaction Name: p14-ARF transcription is stimulated by RUNX proteins
See in Reactome
R-HSA-1234167
(
R-HSA-1234158
)
R-HSA-1234167
Reaction Name: Formation of HIF:CBP:p300 complex at promoters
See in Reactome
R-HSA-9617758
(
R-HSA-9617629
)
R-HSA-9038163
(
R-HSA-9018519
)
R-HSA-9038163
Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
See in Reactome
R-HSA-9016751
(
R-HSA-9013508
)
R-HSA-9016751
Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3
See in Reactome
R-HSA-6782211
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782211
Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site
See in Reactome
R-HSA-560498
(
R-HSA-381340
)
R-HSA-560498
Reaction Name: Expression of Lipoprotein lipase (LPL)
See in Reactome
R-HSA-1980065
(
R-HSA-2122947
)
R-HSA-1980065
Reaction Name: NOTCH1 stimulates HEY transcription
See in Reactome
R-HSA-9759332
()
R-HSA-9759332
Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter
See in Reactome
R-HSA-9613451
(
R-HSA-9031628
)
R-HSA-9613451
Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
See in Reactome
R-HSA-8936621
(
R-HSA-8936459
)
R-HSA-8936621
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
See in Reactome
R-HSA-5628871
(
R-HSA-6804758
)
R-HSA-5628871
Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53
See in Reactome
R-HSA-1980067
(
R-HSA-2122947
)
R-HSA-1980067
Reaction Name: NOTCH1 stimulates MYC transcription
See in Reactome
R-HSA-9620723
(
R-HSA-9031628
)
R-HSA-5250938
(
R-HSA-5250924
)
R-HSA-5250938
Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
See in Reactome
R-HSA-6782204
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782204
Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
See in Reactome
R-HSA-5617867
(
R-HSA-5617472
)
R-HSA-9761849
()
R-HSA-9761849
Reaction Name: AcK-NFE2L2-dependent P6GD gene expression
See in Reactome
R-HSA-9023884
(
R-HSA-9018519
)
R-HSA-9023884
Reaction Name: NCOA1 recruits EP300 to TGFA promoter
See in Reactome
R-HSA-8937050
(
R-HSA-8936459
)
R-HSA-8937050
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
See in Reactome
R-HSA-8952081
(
R-HSA-8951936
)
R-HSA-8952081
Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
See in Reactome
R-HSA-3662335
(
R-HSA-3214847
)
R-HSA-3662335
Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4
See in Reactome
R-HSA-1183003
(
R-HSA-381340
)
R-HSA-6804379
(
R-HSA-6804760
)
R-HSA-4088162
(
R-HSA-156711
)
R-HSA-3134883
(
R-HSA-3134973
)
R-HSA-3134883
Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300
See in Reactome
R-HSA-381309
(
R-HSA-381340
)
R-HSA-381309
Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands
See in Reactome
R-HSA-9023846
(
R-HSA-9018519
)
R-HSA-9023846
Reaction Name: Estrogen-responsive CTSD expression
See in Reactome
R-HSA-1028820
(
R-HSA-933541
)
R-HSA-1028820
Reaction Name: Formation of VAF (virus-activated factor) complex
See in Reactome
R-HSA-8878243
(
R-HSA-8941856
)
R-HSA-8878243
Reaction Name: HES1 gene transcription is inhibited by RUNX3
See in Reactome
R-HSA-9021450
(
R-HSA-9013508
)
R-HSA-9021450
Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes
See in Reactome
R-HSA-9761828
()
R-HSA-1028817
(
R-HSA-918233
)
R-HSA-1028817
Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3
See in Reactome
R-HSA-9008315
(
R-HSA-9018519
)
R-HSA-9008315
Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen
See in Reactome
R-HSA-8936628
(
R-HSA-8936459
)
R-HSA-8936628
Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9023860
(
R-HSA-9018519
)
R-HSA-9023860
Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene
See in Reactome
R-HSA-9761846
()
R-HSA-9761846
Reaction Name: NFE2L2-dependent PGD gene expression
See in Reactome
R-HSA-8936481
(
R-HSA-8936459
)
R-HSA-8936481
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
See in Reactome
R-HSA-5663264
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-6805650
(
R-HSA-6804758
)
R-HSA-6805650
Reaction Name: MTA2-NuRD complex deacetylates TP53
See in Reactome
R-HSA-5617452
(
R-HSA-5617472
)
R-HSA-5617452
Reaction Name: Retinoic acid activates HOXB1 chromatin
See in Reactome
R-HSA-4396347
(
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-4396347
Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter
See in Reactome
R-HSA-9759141
()
R-HSA-9759141
Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene
See in Reactome
R-HSA-9760125
()
R-HSA-9760125
Reaction Name: AcK-NFE2L2-dependent GCLM gene expression
See in Reactome
R-HSA-9613460
(
R-HSA-9031628
)
R-HSA-9620717
(
R-HSA-9031628
)
R-HSA-9620717
Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter
See in Reactome
R-HSA-8951951
(
R-HSA-8951936
)
R-HSA-9029561
(
R-HSA-9029569
)
R-HSA-9029561
Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter
See in Reactome
R-HSA-560473
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-9622604
(
R-HSA-9614657
)
R-HSA-9622604
Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y
See in Reactome
R-HSA-9617064
(
R-HSA-9616222
)
R-HSA-9617064
Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
See in Reactome
R-HSA-9008285
(
R-HSA-9018519
)
R-HSA-9008285
Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
See in Reactome
R-HSA-3371554
(
R-HSA-3371568
)
R-HSA-9701531
(
R-HSA-9701898
)
R-HSA-9701531
Reaction Name: p-Y705,S727 STAT3 is acetylated
See in Reactome
R-HSA-9017835
(
R-HSA-1912408
)
R-HSA-9017835
Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene
See in Reactome
R-HSA-8937097
(
R-HSA-8936459
)
R-HSA-8937097
Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-8936616
(
R-HSA-8936459
)
R-HSA-8936616
Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene
See in Reactome
R-HSA-5663246
(
R-HSA-400253
)
R-HSA-6804229
(
R-HSA-6804760
)
R-HSA-1801587
(
R-HSA-1368082;
R-HSA-1989781;
R-HSA-400253
)
R-HSA-8878056
(
R-HSA-8939243
)
R-HSA-9761812
()
R-HSA-9761812
Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
See in Reactome
R-HSA-4396382
(
R-HSA-2122947
)
R-HSA-4396382
Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes
See in Reactome
R-HSA-5617454
(
R-HSA-5617472
)
R-HSA-560510
(
R-HSA-381340
)
R-HSA-9760097
()
R-HSA-9760097
Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene
See in Reactome
R-HSA-6782004
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782004
Reaction Name: Assembly of the pre-incision complex in TC-NER
See in Reactome
R-HSA-5250930
(
R-HSA-5250924
)
R-HSA-5250930
Reaction Name: B-WICH recruits histone acetyltransferases
See in Reactome
R-HSA-8937016
(
R-HSA-8936459
)
R-HSA-8937016
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
See in Reactome
R-HSA-400342
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-6782138
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782138
Reaction Name: ERCC5 and RPA bind TC-NER site
See in Reactome
R-HSA-5617859
(
R-HSA-5617472
)
R-HSA-5617859
Reaction Name: Retinoic acid activates HOXB4 chromatin
See in Reactome
R-HSA-8952058
(
R-HSA-8951936
)
R-HSA-8952058
Reaction Name: CCND1 binds RUNX3 and displaces EP300
See in Reactome
R-HSA-1980047
(
R-HSA-210744;
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-1980047
Reaction Name: NOTCH1 stimulates HES1 transcription
See in Reactome
R-HSA-1235037
(
R-HSA-1234158
)
R-HSA-8878237
(
R-HSA-8941856
)
R-HSA-8878237
Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter
See in Reactome
R-HSA-9622579
(
R-HSA-9614657
)
R-HSA-9622579
Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter
See in Reactome
R-HSA-9620515
(
R-HSA-9617629
)
R-HSA-9620515
Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress
See in Reactome
R-HSA-933536
(
R-HSA-933541
)
R-HSA-933536
Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300
See in Reactome
R-HSA-9760128
()
R-HSA-9760128
Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression
See in Reactome
R-HSA-9617683
(
R-HSA-9617629
)
R-HSA-9617683
Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4
See in Reactome
R-HSA-1912415
(
R-HSA-1912408
)
R-HSA-1028812
(
R-HSA-918233
)
R-HSA-5693644
(
R-HSA-5617472
)
R-HSA-5693644
Reaction Name: HOXB1 maintains activation of HOXB1 chromatin
See in Reactome
R-HSA-9760082
()
R-HSA-1912394
(
R-HSA-2122947
)
R-HSA-1912394
Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML
See in Reactome
R-HSA-560493
(
R-HSA-381340
)
R-HSA-5617862
(
R-HSA-5617472
)
R-HSA-5617862
Reaction Name: Retinoic acid activates HOXA4 chromatin
See in Reactome
R-HSA-560517
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-560517
Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT)
See in Reactome
R-HSA-1912393
(
R-HSA-2122947
)
R-HSA-1912393
Reaction Name: MAML in complex with NICD1 recruits CDK8
See in Reactome
R-HSA-8935731
(
R-HSA-8936459
)
R-HSA-8935731
Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-6782208
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782208
Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
See in Reactome
R-HSA-5663293
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-1028819
(
R-HSA-933541
)
R-HSA-1028819
Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes
See in Reactome
R-HSA-5660666
(
R-HSA-5621575
)
R-HSA-5660666
Reaction Name: CBP and p300 binds NF-kB complex
See in Reactome
R-HSA-1912416
(
R-HSA-1912408
)
R-HSA-1912391
(
R-HSA-2122947
)
R-HSA-1912391
Reaction Name: NICD1 is phosphorylated by CDK8
See in Reactome
R-HSA-9761815
()
R-HSA-9761815
Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene
See in Reactome
R-HSA-549475
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-9760122
()
R-HSA-9760122
Reaction Name: AcK-NFE2L2-dependent GCLC gene expression
See in Reactome
R-HSA-6782227
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782227
Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER
See in Reactome
R-HSA-6811508
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-6811508
Reaction Name: ING2-bound EP300 acetylates TP53
See in Reactome
R-HSA-1235035
(
R-HSA-1234158
)
R-HSA-1235035
Reaction Name: Expression of Carbonic Anhydrase IX (CA9)
See in Reactome
R-HSA-9021451
(
R-HSA-9013508
)
R-HSA-9021451
Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter
See in Reactome
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9023840
(
R-HSA-9018519
)
R-HSA-9023840
Reaction Name: HATs and coactivators are recruited to the CTSD gene
See in Reactome
R-HSA-6811479
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-5617877
(
R-HSA-5617472
)
R-HSA-8864307
(
R-HSA-8866907
)
R-HSA-8864307
Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
See in Reactome
R-HSA-1028815
(
R-HSA-918233
)
R-HSA-1028815
Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta
See in Reactome
R-HSA-6804383
(
R-HSA-6804760
)
R-HSA-6782234
(
R-HSA-6781827
)
R-HSA-6782234
Reaction Name: Recovery of RNA synthesis after TC-NER
See in Reactome
R-HSA-9011975
(
R-HSA-9018519
)
R-HSA-9011975
Reaction Name: Estrogen-responsive MYC gene expression
See in Reactome
R-HSA-8878220
(
R-HSA-8941856
)
R-HSA-8878220
Reaction Name: RUNX3 binds the NOTCH1 coactivator complex
See in Reactome
R-HSA-2976551
(
R-HSA-2197563
)
R-HSA-2976551
Reaction Name: NOTCH2 stimulates GZMB transcription
See in Reactome
R-HSA-1368081
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-5617431
(
R-HSA-5617472
)
R-HSA-5617431
Reaction Name: Retinoic acid activates HOXA1 chromatin
See in Reactome
R-HSA-1980078
(
R-HSA-2122947
)
R-HSA-1980078
Reaction Name: NOTCH1 stimulates HES5 transcription
See in Reactome
R-HSA-4396379
(
R-HSA-2122947
)
R-HSA-4396379
Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter
See in Reactome
R-HSA-3215152
(
R-HSA-6804114
)
R-HSA-3215152
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
See in Reactome
R-HSA-4088152
(
R-HSA-156711
)
R-HSA-4088152
Reaction Name: FOXM1 stimulates CDC25A transcription
See in Reactome
R-HSA-9009371
(
R-HSA-9018519
)
R-HSA-9009371
Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter
See in Reactome
R-HSA-9023859
(
R-HSA-9018519
)
R-HSA-9023859
Reaction Name: Estrogen-responsive TFF1 gene expression
See in Reactome
R-HSA-1368087
(
R-HSA-400253
)
R-HSA-1368087
Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene
See in Reactome
R-HSA-1368065
(
R-HSA-1989781;
R-HSA-400253;
R-HSA-9707616
)
R-HSA-1183058
(
R-HSA-381340
)
R-HSA-9622572
(
R-HSA-9614657
)
R-HSA-9622572
Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
See in Reactome
R-HSA-3899291
(
R-HSA-3899300
)
R-HSA-3899291
Reaction Name: SUMOylation of EP300 with SUMO1
See in Reactome
R-HSA-9634433
(
R-HSA-9616222
)
R-HSA-9634433
Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid
See in Reactome
R-HSA-9605057
(
R-HSA-9029569
)
R-HSA-9605057
Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3
See in Reactome
R-HSA-5617471
(
R-HSA-5617472
)
R-HSA-9761841
()
R-HSA-9761841
Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression
See in Reactome
R-HSA-5691381
(
R-HSA-5689901
)
R-HSA-5691381
Reaction Name: MYSM1 deubiquitinates Histone H2A
See in Reactome
R-HSA-5617874
(
R-HSA-5617472
)
R-HSA-9760099
()
R-HSA-9760099
Reaction Name: AcK-NFE2L2 binds the GCLC gene
See in Reactome
R-HSA-9018499
(
R-HSA-9018519
)
R-HSA-9018499
Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter
See in Reactome
R-HSA-9760103
()
R-HSA-9760103
Reaction Name: AcK-NFE2L2 binds the GCLM gene
See in Reactome
R-HSA-560472
(
R-HSA-381340
)
R-HSA-560472
Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
See in Reactome
R-HSA-6782131
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782131
Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-8935740
(
R-HSA-8936459
)
R-HSA-8935740
Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene
See in Reactome
R-HSA-9009378
(
R-HSA-9018519
)
R-HSA-9009378
Reaction Name: Estrogen-responsive CCND1 gene expression
See in Reactome
R-HSA-8952419
(
R-HSA-8941858
)
R-HSA-6782224
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782224
Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER
See in Reactome
R-HSA-8936979
(
R-HSA-8936459
)
R-HSA-8936979
Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene
See in Reactome
R-HSA-1235070
(
R-HSA-1234158
)
R-HSA-1235070
Reaction Name: Expression of Erythropoietin (EPO)
See in Reactome
R-HSA-5660660
(
R-HSA-5621575
)
R-HSA-3215144
(
R-HSA-6804114
)
R-HSA-3215144
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription
See in Reactome
R-HSA-8951966
(
R-HSA-8951936
)
R-HSA-9008271
(
R-HSA-9018519
)
R-HSA-9008271
Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
See in Reactome
R-HSA-9011941
(
R-HSA-9018519
)
R-HSA-9011941
Reaction Name: Estrogen-responsive BCL2 gene expression
See in Reactome
R-HSA-2976563
(
R-HSA-2197563
)
R-HSA-2976563
Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
See in Reactome
R-HSA-5663273
(
R-HSA-400253
)
R-HSA-5663273
Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene
See in Reactome
R-HSA-9604499
(
R-HSA-933541
)
R-HSA-9604499
Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300
See in Reactome
R-HSA-9604664
(
R-HSA-9013695
)
R-HSA-9604664
Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
See in Reactome
R-HSA-6782141
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782141
Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
See in Reactome
R-HSA-5617896
(
R-HSA-5617472
)
R-HSA-5617896
Reaction Name: Retinoic acid activates HOXD4 chromatin
See in Reactome
R-HSA-8937037
(
R-HSA-8936459
)
R-HSA-8937037
Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene
See in Reactome
R-HSA-9759364
()
R-HSA-9759364
Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression
See in Reactome
R-HSA-9617735
(
R-HSA-9617629
)
R-HSA-9617735
Reaction Name: TXN disrupts FOXO4 complex with EP300
See in Reactome
R-HSA-3322427
(
R-HSA-201722
)
R-HSA-3322427
Reaction Name: Beta-catenin recruits CBP/p300
See in Reactome
R-HSA-9018497
(
R-HSA-9018519
)
R-HSA-9018497
Reaction Name: Estrogen-responsive TFF3 gene expression
See in Reactome
R-HSA-8936995
(
R-HSA-8936459
)
R-HSA-8936995
Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9684118
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-9684118
Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-6804242
(
R-HSA-6804760
)
R-HSA-6804242
Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5
See in Reactome
R-HSA-9759186
()
R-HSA-9759186
Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression
See in Reactome
R-HSA-3222093
(
R-HSA-6804758
)
|
MONDO:0009693 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0010150 |
EP300 |
Q09472 |
2.3.1.-
2.3.1.48
|
R-HSA-9617629
R-HSA-9617629
Reactome Name: Regulation of FOXO transcriptional activity by acetylation
See in Reactome
R-HSA-210744
R-HSA-210744
Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
See in Reactome
R-HSA-5689901
R-HSA-6804760
R-HSA-6804760
Reactome Name: Regulation of TP53 Activity through Methylation
See in Reactome
R-HSA-8939243
R-HSA-8939243
Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
See in Reactome
R-HSA-381340
R-HSA-381340
Reactome Name: Transcriptional regulation of white adipocyte differentiation
See in Reactome
R-HSA-9616222
R-HSA-9616222
Reactome Name: Transcriptional regulation of granulopoiesis
See in Reactome
R-HSA-9013695
R-HSA-9013695
Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-6782135
R-HSA-6782210
R-HSA-6782210
Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER
See in Reactome
R-HSA-8941856
R-HSA-8941856
Reactome Name: RUNX3 regulates NOTCH signaling
See in Reactome
R-HSA-8941858
R-HSA-8941858
Reactome Name: Regulation of RUNX3 expression and activity
See in Reactome
R-HSA-6804114
R-HSA-6804114
Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
See in Reactome
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-918233
R-HSA-918233
Reactome Name: TRAF3-dependent IRF activation pathway
See in Reactome
R-HSA-6781827
R-HSA-6781827
Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
See in Reactome
R-HSA-156711
R-HSA-156711
Reactome Name: Polo-like kinase mediated events
See in Reactome
R-HSA-5250924
R-HSA-5250924
Reactome Name: B-WICH complex positively regulates rRNA expression
See in Reactome
R-HSA-6781823
R-HSA-6781823
Reactome Name: Formation of TC-NER Pre-Incision Complex
See in Reactome
R-HSA-9013508
R-HSA-9013508
Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-3214847
R-HSA-3371568
R-HSA-8866907
R-HSA-8866907
Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors
See in Reactome
R-HSA-9614657
R-HSA-9614657
Reactome Name: FOXO-mediated transcription of cell death genes
See in Reactome
R-HSA-9701898
R-HSA-9701898
Reactome Name: STAT3 nuclear events downstream of ALK signaling
See in Reactome
R-HSA-933541
R-HSA-1234158
R-HSA-1234158
Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor
See in Reactome
R-HSA-1368082
R-HSA-1368082
Reactome Name: RORA activates gene expression
See in Reactome
R-HSA-5617472
R-HSA-5617472
Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis
See in Reactome
R-HSA-3899300
R-HSA-3899300
Reactome Name: SUMOylation of transcription cofactors
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8936459
R-HSA-8936459
Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-2197563
R-HSA-2197563
Reactome Name: NOTCH2 intracellular domain regulates transcription
See in Reactome
R-HSA-400253
R-HSA-9707616
R-HSA-3134973
R-HSA-3134973
Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
See in Reactome
R-HSA-201722
R-HSA-201722
Reactome Name: Formation of the beta-catenin:TCF transactivating complex
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8951936
R-HSA-5621575
R-HSA-9031628
R-HSA-6811555
R-HSA-6811555
Reactome Name: PI5P Regulates TP53 Acetylation
See in Reactome
R-HSA-6804758
R-HSA-6804758
Reactome Name: Regulation of TP53 Activity through Acetylation
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-9012852
R-HSA-5633007
R-HSA-168256
R-HSA-9013694
R-HSA-168928
R-HSA-168928
Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta
See in Reactome
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-6791312
R-HSA-6791312
Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-1430728
R-HSA-8864260
R-HSA-8864260
Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-2262752
R-HSA-73894
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-2990846
R-HSA-556833
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-8953897
R-HSA-212165
R-HSA-212165
Reactome Name: Epigenetic regulation of gene expression
See in Reactome
R-HSA-5696398
R-HSA-168249
R-HSA-453274
R-HSA-392499
R-HSA-1234174
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-1980143
R-HSA-8939211
R-HSA-1834949
R-HSA-1834949
Reactome Name: Cytosolic sensors of pathogen-associated DNA
See in Reactome
R-HSA-186712
R-HSA-186712
Reactome Name: Regulation of beta-cell development
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-157118
R-HSA-187037
R-HSA-3247509
R-HSA-195721
R-HSA-1980145
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9614085
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-5688426
R-HSA-201556
R-HSA-5250913
R-HSA-5250913
Reactome Name: Positive epigenetic regulation of rRNA expression
See in Reactome
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-4839726
R-HSA-69275
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-162582
R-HSA-5619507
R-HSA-5619507
Reactome Name: Activation of HOX genes during differentiation
See in Reactome
|
Circadian Clock
Immune System
Cell Cycle
Developmental Biology
Metabolism
Gene expression (Transcription)
DNA Repair
Cellular responses to stimuli
Metabolism of proteins
Chromatin organization
Signal Transduction
|
R-HSA-6782069
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782069
Reaction Name: UVSSA:USP7 deubiquitinates ERCC6
See in Reactome
R-HSA-9760081
()
R-HSA-9760081
Reaction Name: CREBBP, EP300 acetylates NFE2L2
See in Reactome
R-HSA-9011981
(
R-HSA-9018519
)
R-HSA-9011981
Reaction Name: EP300 is recruited to MYC and BCL2 genes
See in Reactome
R-HSA-8878050
(
R-HSA-8939243
)
R-HSA-8878050
Reaction Name: HIPK2 phosphorylates RUNX1 and EP300
See in Reactome
R-HSA-9761836
()
R-HSA-9761836
Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300
See in Reactome
R-HSA-560491
(
R-HSA-381340
)
R-HSA-4396371
(
R-HSA-2122947
)
R-HSA-4396371
Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter
See in Reactome
R-HSA-9038052
(
R-HSA-9018519
)
R-HSA-9038052
Reaction Name: GREB1 binds ESR1:ESTG and co-activators
See in Reactome
R-HSA-8952101
(
R-HSA-8951936
)
R-HSA-8952101
Reaction Name: p14-ARF transcription is stimulated by RUNX proteins
See in Reactome
R-HSA-1234167
(
R-HSA-1234158
)
R-HSA-1234167
Reaction Name: Formation of HIF:CBP:p300 complex at promoters
See in Reactome
R-HSA-9617758
(
R-HSA-9617629
)
R-HSA-9038163
(
R-HSA-9018519
)
R-HSA-9038163
Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
See in Reactome
R-HSA-9016751
(
R-HSA-9013508
)
R-HSA-9016751
Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3
See in Reactome
R-HSA-6782211
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782211
Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site
See in Reactome
R-HSA-560498
(
R-HSA-381340
)
R-HSA-560498
Reaction Name: Expression of Lipoprotein lipase (LPL)
See in Reactome
R-HSA-1980065
(
R-HSA-2122947
)
R-HSA-1980065
Reaction Name: NOTCH1 stimulates HEY transcription
See in Reactome
R-HSA-9759332
()
R-HSA-9759332
Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter
See in Reactome
R-HSA-9613451
(
R-HSA-9031628
)
R-HSA-9613451
Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
See in Reactome
R-HSA-8936621
(
R-HSA-8936459
)
R-HSA-8936621
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
See in Reactome
R-HSA-5628871
(
R-HSA-6804758
)
R-HSA-5628871
Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53
See in Reactome
R-HSA-1980067
(
R-HSA-2122947
)
R-HSA-1980067
Reaction Name: NOTCH1 stimulates MYC transcription
See in Reactome
R-HSA-9620723
(
R-HSA-9031628
)
R-HSA-5250938
(
R-HSA-5250924
)
R-HSA-5250938
Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
See in Reactome
R-HSA-6782204
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782204
Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
See in Reactome
R-HSA-5617867
(
R-HSA-5617472
)
R-HSA-9761849
()
R-HSA-9761849
Reaction Name: AcK-NFE2L2-dependent P6GD gene expression
See in Reactome
R-HSA-9023884
(
R-HSA-9018519
)
R-HSA-9023884
Reaction Name: NCOA1 recruits EP300 to TGFA promoter
See in Reactome
R-HSA-8937050
(
R-HSA-8936459
)
R-HSA-8937050
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
See in Reactome
R-HSA-8952081
(
R-HSA-8951936
)
R-HSA-8952081
Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
See in Reactome
R-HSA-3662335
(
R-HSA-3214847
)
R-HSA-3662335
Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4
See in Reactome
R-HSA-1183003
(
R-HSA-381340
)
R-HSA-6804379
(
R-HSA-6804760
)
R-HSA-4088162
(
R-HSA-156711
)
R-HSA-3134883
(
R-HSA-3134973
)
R-HSA-3134883
Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300
See in Reactome
R-HSA-381309
(
R-HSA-381340
)
R-HSA-381309
Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands
See in Reactome
R-HSA-9023846
(
R-HSA-9018519
)
R-HSA-9023846
Reaction Name: Estrogen-responsive CTSD expression
See in Reactome
R-HSA-1028820
(
R-HSA-933541
)
R-HSA-1028820
Reaction Name: Formation of VAF (virus-activated factor) complex
See in Reactome
R-HSA-8878243
(
R-HSA-8941856
)
R-HSA-8878243
Reaction Name: HES1 gene transcription is inhibited by RUNX3
See in Reactome
R-HSA-9021450
(
R-HSA-9013508
)
R-HSA-9021450
Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes
See in Reactome
R-HSA-9761828
()
R-HSA-1028817
(
R-HSA-918233
)
R-HSA-1028817
Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3
See in Reactome
R-HSA-9008315
(
R-HSA-9018519
)
R-HSA-9008315
Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen
See in Reactome
R-HSA-8936628
(
R-HSA-8936459
)
R-HSA-8936628
Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9023860
(
R-HSA-9018519
)
R-HSA-9023860
Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene
See in Reactome
R-HSA-9761846
()
R-HSA-9761846
Reaction Name: NFE2L2-dependent PGD gene expression
See in Reactome
R-HSA-8936481
(
R-HSA-8936459
)
R-HSA-8936481
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
See in Reactome
R-HSA-5663264
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-6805650
(
R-HSA-6804758
)
R-HSA-6805650
Reaction Name: MTA2-NuRD complex deacetylates TP53
See in Reactome
R-HSA-5617452
(
R-HSA-5617472
)
R-HSA-5617452
Reaction Name: Retinoic acid activates HOXB1 chromatin
See in Reactome
R-HSA-4396347
(
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-4396347
Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter
See in Reactome
R-HSA-9759141
()
R-HSA-9759141
Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene
See in Reactome
R-HSA-9760125
()
R-HSA-9760125
Reaction Name: AcK-NFE2L2-dependent GCLM gene expression
See in Reactome
R-HSA-9613460
(
R-HSA-9031628
)
R-HSA-9620717
(
R-HSA-9031628
)
R-HSA-9620717
Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter
See in Reactome
R-HSA-8951951
(
R-HSA-8951936
)
R-HSA-9029561
(
R-HSA-9029569
)
R-HSA-9029561
Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter
See in Reactome
R-HSA-560473
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-9622604
(
R-HSA-9614657
)
R-HSA-9622604
Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y
See in Reactome
R-HSA-9617064
(
R-HSA-9616222
)
R-HSA-9617064
Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
See in Reactome
R-HSA-9008285
(
R-HSA-9018519
)
R-HSA-9008285
Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
See in Reactome
R-HSA-3371554
(
R-HSA-3371568
)
R-HSA-9701531
(
R-HSA-9701898
)
R-HSA-9701531
Reaction Name: p-Y705,S727 STAT3 is acetylated
See in Reactome
R-HSA-9017835
(
R-HSA-1912408
)
R-HSA-9017835
Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene
See in Reactome
R-HSA-8937097
(
R-HSA-8936459
)
R-HSA-8937097
Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-8936616
(
R-HSA-8936459
)
R-HSA-8936616
Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene
See in Reactome
R-HSA-5663246
(
R-HSA-400253
)
R-HSA-6804229
(
R-HSA-6804760
)
R-HSA-1801587
(
R-HSA-1368082;
R-HSA-1989781;
R-HSA-400253
)
R-HSA-8878056
(
R-HSA-8939243
)
R-HSA-9761812
()
R-HSA-9761812
Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
See in Reactome
R-HSA-4396382
(
R-HSA-2122947
)
R-HSA-4396382
Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes
See in Reactome
R-HSA-5617454
(
R-HSA-5617472
)
R-HSA-560510
(
R-HSA-381340
)
R-HSA-9760097
()
R-HSA-9760097
Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene
See in Reactome
R-HSA-6782004
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782004
Reaction Name: Assembly of the pre-incision complex in TC-NER
See in Reactome
R-HSA-5250930
(
R-HSA-5250924
)
R-HSA-5250930
Reaction Name: B-WICH recruits histone acetyltransferases
See in Reactome
R-HSA-8937016
(
R-HSA-8936459
)
R-HSA-8937016
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
See in Reactome
R-HSA-400342
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-6782138
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782138
Reaction Name: ERCC5 and RPA bind TC-NER site
See in Reactome
R-HSA-5617859
(
R-HSA-5617472
)
R-HSA-5617859
Reaction Name: Retinoic acid activates HOXB4 chromatin
See in Reactome
R-HSA-8952058
(
R-HSA-8951936
)
R-HSA-8952058
Reaction Name: CCND1 binds RUNX3 and displaces EP300
See in Reactome
R-HSA-1980047
(
R-HSA-210744;
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-1980047
Reaction Name: NOTCH1 stimulates HES1 transcription
See in Reactome
R-HSA-1235037
(
R-HSA-1234158
)
R-HSA-8878237
(
R-HSA-8941856
)
R-HSA-8878237
Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter
See in Reactome
R-HSA-9622579
(
R-HSA-9614657
)
R-HSA-9622579
Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter
See in Reactome
R-HSA-9620515
(
R-HSA-9617629
)
R-HSA-9620515
Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress
See in Reactome
R-HSA-933536
(
R-HSA-933541
)
R-HSA-933536
Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300
See in Reactome
R-HSA-9760128
()
R-HSA-9760128
Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression
See in Reactome
R-HSA-9617683
(
R-HSA-9617629
)
R-HSA-9617683
Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4
See in Reactome
R-HSA-1912415
(
R-HSA-1912408
)
R-HSA-1028812
(
R-HSA-918233
)
R-HSA-5693644
(
R-HSA-5617472
)
R-HSA-5693644
Reaction Name: HOXB1 maintains activation of HOXB1 chromatin
See in Reactome
R-HSA-9760082
()
R-HSA-1912394
(
R-HSA-2122947
)
R-HSA-1912394
Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML
See in Reactome
R-HSA-560493
(
R-HSA-381340
)
R-HSA-5617862
(
R-HSA-5617472
)
R-HSA-5617862
Reaction Name: Retinoic acid activates HOXA4 chromatin
See in Reactome
R-HSA-560517
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-560517
Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT)
See in Reactome
R-HSA-1912393
(
R-HSA-2122947
)
R-HSA-1912393
Reaction Name: MAML in complex with NICD1 recruits CDK8
See in Reactome
R-HSA-8935731
(
R-HSA-8936459
)
R-HSA-8935731
Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-6782208
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782208
Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
See in Reactome
R-HSA-5663293
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-1028819
(
R-HSA-933541
)
R-HSA-1028819
Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes
See in Reactome
R-HSA-5660666
(
R-HSA-5621575
)
R-HSA-5660666
Reaction Name: CBP and p300 binds NF-kB complex
See in Reactome
R-HSA-1912416
(
R-HSA-1912408
)
R-HSA-1912391
(
R-HSA-2122947
)
R-HSA-1912391
Reaction Name: NICD1 is phosphorylated by CDK8
See in Reactome
R-HSA-9761815
()
R-HSA-9761815
Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene
See in Reactome
R-HSA-549475
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-9760122
()
R-HSA-9760122
Reaction Name: AcK-NFE2L2-dependent GCLC gene expression
See in Reactome
R-HSA-6782227
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782227
Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER
See in Reactome
R-HSA-6811508
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-6811508
Reaction Name: ING2-bound EP300 acetylates TP53
See in Reactome
R-HSA-1235035
(
R-HSA-1234158
)
R-HSA-1235035
Reaction Name: Expression of Carbonic Anhydrase IX (CA9)
See in Reactome
R-HSA-9021451
(
R-HSA-9013508
)
R-HSA-9021451
Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter
See in Reactome
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9023840
(
R-HSA-9018519
)
R-HSA-9023840
Reaction Name: HATs and coactivators are recruited to the CTSD gene
See in Reactome
R-HSA-6811479
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-5617877
(
R-HSA-5617472
)
R-HSA-8864307
(
R-HSA-8866907
)
R-HSA-8864307
Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
See in Reactome
R-HSA-1028815
(
R-HSA-918233
)
R-HSA-1028815
Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta
See in Reactome
R-HSA-6804383
(
R-HSA-6804760
)
R-HSA-6782234
(
R-HSA-6781827
)
R-HSA-6782234
Reaction Name: Recovery of RNA synthesis after TC-NER
See in Reactome
R-HSA-9011975
(
R-HSA-9018519
)
R-HSA-9011975
Reaction Name: Estrogen-responsive MYC gene expression
See in Reactome
R-HSA-8878220
(
R-HSA-8941856
)
R-HSA-8878220
Reaction Name: RUNX3 binds the NOTCH1 coactivator complex
See in Reactome
R-HSA-2976551
(
R-HSA-2197563
)
R-HSA-2976551
Reaction Name: NOTCH2 stimulates GZMB transcription
See in Reactome
R-HSA-1368081
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-5617431
(
R-HSA-5617472
)
R-HSA-5617431
Reaction Name: Retinoic acid activates HOXA1 chromatin
See in Reactome
R-HSA-1980078
(
R-HSA-2122947
)
R-HSA-1980078
Reaction Name: NOTCH1 stimulates HES5 transcription
See in Reactome
R-HSA-4396379
(
R-HSA-2122947
)
R-HSA-4396379
Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter
See in Reactome
R-HSA-3215152
(
R-HSA-6804114
)
R-HSA-3215152
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
See in Reactome
R-HSA-4088152
(
R-HSA-156711
)
R-HSA-4088152
Reaction Name: FOXM1 stimulates CDC25A transcription
See in Reactome
R-HSA-9009371
(
R-HSA-9018519
)
R-HSA-9009371
Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter
See in Reactome
R-HSA-9023859
(
R-HSA-9018519
)
R-HSA-9023859
Reaction Name: Estrogen-responsive TFF1 gene expression
See in Reactome
R-HSA-1368087
(
R-HSA-400253
)
R-HSA-1368087
Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene
See in Reactome
R-HSA-1368065
(
R-HSA-1989781;
R-HSA-400253;
R-HSA-9707616
)
R-HSA-1183058
(
R-HSA-381340
)
R-HSA-9622572
(
R-HSA-9614657
)
R-HSA-9622572
Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
See in Reactome
R-HSA-3899291
(
R-HSA-3899300
)
R-HSA-3899291
Reaction Name: SUMOylation of EP300 with SUMO1
See in Reactome
R-HSA-9634433
(
R-HSA-9616222
)
R-HSA-9634433
Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid
See in Reactome
R-HSA-9605057
(
R-HSA-9029569
)
R-HSA-9605057
Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3
See in Reactome
R-HSA-5617471
(
R-HSA-5617472
)
R-HSA-9761841
()
R-HSA-9761841
Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression
See in Reactome
R-HSA-5691381
(
R-HSA-5689901
)
R-HSA-5691381
Reaction Name: MYSM1 deubiquitinates Histone H2A
See in Reactome
R-HSA-5617874
(
R-HSA-5617472
)
R-HSA-9760099
()
R-HSA-9760099
Reaction Name: AcK-NFE2L2 binds the GCLC gene
See in Reactome
R-HSA-9018499
(
R-HSA-9018519
)
R-HSA-9018499
Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter
See in Reactome
R-HSA-9760103
()
R-HSA-9760103
Reaction Name: AcK-NFE2L2 binds the GCLM gene
See in Reactome
R-HSA-560472
(
R-HSA-381340
)
R-HSA-560472
Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
See in Reactome
R-HSA-6782131
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782131
Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-8935740
(
R-HSA-8936459
)
R-HSA-8935740
Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene
See in Reactome
R-HSA-9009378
(
R-HSA-9018519
)
R-HSA-9009378
Reaction Name: Estrogen-responsive CCND1 gene expression
See in Reactome
R-HSA-8952419
(
R-HSA-8941858
)
R-HSA-6782224
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782224
Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER
See in Reactome
R-HSA-8936979
(
R-HSA-8936459
)
R-HSA-8936979
Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene
See in Reactome
R-HSA-1235070
(
R-HSA-1234158
)
R-HSA-1235070
Reaction Name: Expression of Erythropoietin (EPO)
See in Reactome
R-HSA-5660660
(
R-HSA-5621575
)
R-HSA-3215144
(
R-HSA-6804114
)
R-HSA-3215144
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription
See in Reactome
R-HSA-8951966
(
R-HSA-8951936
)
R-HSA-9008271
(
R-HSA-9018519
)
R-HSA-9008271
Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
See in Reactome
R-HSA-9011941
(
R-HSA-9018519
)
R-HSA-9011941
Reaction Name: Estrogen-responsive BCL2 gene expression
See in Reactome
R-HSA-2976563
(
R-HSA-2197563
)
R-HSA-2976563
Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
See in Reactome
R-HSA-5663273
(
R-HSA-400253
)
R-HSA-5663273
Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene
See in Reactome
R-HSA-9604499
(
R-HSA-933541
)
R-HSA-9604499
Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300
See in Reactome
R-HSA-9604664
(
R-HSA-9013695
)
R-HSA-9604664
Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
See in Reactome
R-HSA-6782141
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782141
Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
See in Reactome
R-HSA-5617896
(
R-HSA-5617472
)
R-HSA-5617896
Reaction Name: Retinoic acid activates HOXD4 chromatin
See in Reactome
R-HSA-8937037
(
R-HSA-8936459
)
R-HSA-8937037
Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene
See in Reactome
R-HSA-9759364
()
R-HSA-9759364
Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression
See in Reactome
R-HSA-9617735
(
R-HSA-9617629
)
R-HSA-9617735
Reaction Name: TXN disrupts FOXO4 complex with EP300
See in Reactome
R-HSA-3322427
(
R-HSA-201722
)
R-HSA-3322427
Reaction Name: Beta-catenin recruits CBP/p300
See in Reactome
R-HSA-9018497
(
R-HSA-9018519
)
R-HSA-9018497
Reaction Name: Estrogen-responsive TFF3 gene expression
See in Reactome
R-HSA-8936995
(
R-HSA-8936459
)
R-HSA-8936995
Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9684118
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-9684118
Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-6804242
(
R-HSA-6804760
)
R-HSA-6804242
Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5
See in Reactome
R-HSA-9759186
()
R-HSA-9759186
Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression
See in Reactome
R-HSA-3222093
(
R-HSA-6804758
)
|
MONDO:0010854 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0010886 |
HDAC4 |
P56524 |
3.5.1.98
|
R-HSA-8951936
R-HSA-4551638
R-HSA-4551638
Reactome Name: SUMOylation of chromatin organization proteins
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-8941284
R-HSA-8941284
Reactome Name: RUNX2 regulates chondrocyte maturation
See in Reactome
R-HSA-4090294
R-HSA-4090294
Reactome Name: SUMOylation of intracellular receptors
See in Reactome
R-HSA-350054
R-HSA-350054
Reactome Name: Notch-HLH transcription pathway
See in Reactome
|
R-HSA-1980143
R-HSA-212436
R-HSA-74160
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-392499
R-HSA-157118
R-HSA-73857
R-HSA-2990846
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-8941326
R-HSA-8941326
Reactome Name: RUNX2 regulates bone development
See in Reactome
R-HSA-162582
R-HSA-8878166
R-HSA-8878166
Reactome Name: Transcriptional regulation by RUNX2
See in Reactome
|
Gene expression (Transcription)
Metabolism of proteins
Signal Transduction
|
R-HSA-1912388
(
R-HSA-2122947
)
R-HSA-1912388
Reaction Name: NICD1 displaces co-repressor complex from RBPJ (CSL)
See in Reactome
R-HSA-350058
(
R-HSA-350054
)
R-HSA-350058
Reaction Name: Formation of CSL NCOR corepressor complex
See in Reactome
R-HSA-4615872
(
R-HSA-4551638
)
R-HSA-4615872
Reaction Name: RANBP2 SUMOylates HDAC4 with SUMO1
See in Reactome
R-HSA-4615987
(
R-HSA-4551638
)
R-HSA-4615987
Reaction Name: RANBP2 SUMOylates HDAC4 with SUMO2,3
See in Reactome
R-HSA-4720432
(
R-HSA-4090294
)
R-HSA-4720432
Reaction Name: HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3
See in Reactome
R-HSA-4720446
(
R-HSA-4090294
)
R-HSA-4720446
Reaction Name: HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3
See in Reactome
R-HSA-8952062
(
R-HSA-8951936
)
R-HSA-8952069
(
R-HSA-8951936
)
R-HSA-9008326
(
R-HSA-8941284
)
|
MONDO:0011908 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0012371 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0013364 |
EP300 |
Q09472 |
2.3.1.-
2.3.1.48
|
R-HSA-9617629
R-HSA-9617629
Reactome Name: Regulation of FOXO transcriptional activity by acetylation
See in Reactome
R-HSA-210744
R-HSA-210744
Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
See in Reactome
R-HSA-5689901
R-HSA-6804760
R-HSA-6804760
Reactome Name: Regulation of TP53 Activity through Methylation
See in Reactome
R-HSA-8939243
R-HSA-8939243
Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
See in Reactome
R-HSA-381340
R-HSA-381340
Reactome Name: Transcriptional regulation of white adipocyte differentiation
See in Reactome
R-HSA-9616222
R-HSA-9616222
Reactome Name: Transcriptional regulation of granulopoiesis
See in Reactome
R-HSA-9013695
R-HSA-9013695
Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-6782135
R-HSA-6782210
R-HSA-6782210
Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER
See in Reactome
R-HSA-8941856
R-HSA-8941856
Reactome Name: RUNX3 regulates NOTCH signaling
See in Reactome
R-HSA-8941858
R-HSA-8941858
Reactome Name: Regulation of RUNX3 expression and activity
See in Reactome
R-HSA-6804114
R-HSA-6804114
Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
See in Reactome
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-918233
R-HSA-918233
Reactome Name: TRAF3-dependent IRF activation pathway
See in Reactome
R-HSA-6781827
R-HSA-6781827
Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
See in Reactome
R-HSA-156711
R-HSA-156711
Reactome Name: Polo-like kinase mediated events
See in Reactome
R-HSA-5250924
R-HSA-5250924
Reactome Name: B-WICH complex positively regulates rRNA expression
See in Reactome
R-HSA-6781823
R-HSA-6781823
Reactome Name: Formation of TC-NER Pre-Incision Complex
See in Reactome
R-HSA-9013508
R-HSA-9013508
Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-3214847
R-HSA-3371568
R-HSA-8866907
R-HSA-8866907
Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors
See in Reactome
R-HSA-9614657
R-HSA-9614657
Reactome Name: FOXO-mediated transcription of cell death genes
See in Reactome
R-HSA-9701898
R-HSA-9701898
Reactome Name: STAT3 nuclear events downstream of ALK signaling
See in Reactome
R-HSA-933541
R-HSA-1234158
R-HSA-1234158
Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor
See in Reactome
R-HSA-1368082
R-HSA-1368082
Reactome Name: RORA activates gene expression
See in Reactome
R-HSA-5617472
R-HSA-5617472
Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis
See in Reactome
R-HSA-3899300
R-HSA-3899300
Reactome Name: SUMOylation of transcription cofactors
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8936459
R-HSA-8936459
Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-2197563
R-HSA-2197563
Reactome Name: NOTCH2 intracellular domain regulates transcription
See in Reactome
R-HSA-400253
R-HSA-9707616
R-HSA-3134973
R-HSA-3134973
Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
See in Reactome
R-HSA-201722
R-HSA-201722
Reactome Name: Formation of the beta-catenin:TCF transactivating complex
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8951936
R-HSA-5621575
R-HSA-9031628
R-HSA-6811555
R-HSA-6811555
Reactome Name: PI5P Regulates TP53 Acetylation
See in Reactome
R-HSA-6804758
R-HSA-6804758
Reactome Name: Regulation of TP53 Activity through Acetylation
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-9012852
R-HSA-5633007
R-HSA-168256
R-HSA-9013694
R-HSA-168928
R-HSA-168928
Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta
See in Reactome
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-6791312
R-HSA-6791312
Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-1430728
R-HSA-8864260
R-HSA-8864260
Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-2262752
R-HSA-73894
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-2990846
R-HSA-556833
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-8953897
R-HSA-212165
R-HSA-212165
Reactome Name: Epigenetic regulation of gene expression
See in Reactome
R-HSA-5696398
R-HSA-168249
R-HSA-453274
R-HSA-392499
R-HSA-1234174
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-1980143
R-HSA-8939211
R-HSA-1834949
R-HSA-1834949
Reactome Name: Cytosolic sensors of pathogen-associated DNA
See in Reactome
R-HSA-186712
R-HSA-186712
Reactome Name: Regulation of beta-cell development
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-157118
R-HSA-187037
R-HSA-3247509
R-HSA-195721
R-HSA-1980145
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9614085
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-5688426
R-HSA-201556
R-HSA-5250913
R-HSA-5250913
Reactome Name: Positive epigenetic regulation of rRNA expression
See in Reactome
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-4839726
R-HSA-69275
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-162582
R-HSA-5619507
R-HSA-5619507
Reactome Name: Activation of HOX genes during differentiation
See in Reactome
|
Circadian Clock
Immune System
Cell Cycle
Developmental Biology
Metabolism
Gene expression (Transcription)
DNA Repair
Cellular responses to stimuli
Metabolism of proteins
Chromatin organization
Signal Transduction
|
R-HSA-6782069
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782069
Reaction Name: UVSSA:USP7 deubiquitinates ERCC6
See in Reactome
R-HSA-9760081
()
R-HSA-9760081
Reaction Name: CREBBP, EP300 acetylates NFE2L2
See in Reactome
R-HSA-9011981
(
R-HSA-9018519
)
R-HSA-9011981
Reaction Name: EP300 is recruited to MYC and BCL2 genes
See in Reactome
R-HSA-8878050
(
R-HSA-8939243
)
R-HSA-8878050
Reaction Name: HIPK2 phosphorylates RUNX1 and EP300
See in Reactome
R-HSA-9761836
()
R-HSA-9761836
Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300
See in Reactome
R-HSA-560491
(
R-HSA-381340
)
R-HSA-4396371
(
R-HSA-2122947
)
R-HSA-4396371
Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter
See in Reactome
R-HSA-9038052
(
R-HSA-9018519
)
R-HSA-9038052
Reaction Name: GREB1 binds ESR1:ESTG and co-activators
See in Reactome
R-HSA-8952101
(
R-HSA-8951936
)
R-HSA-8952101
Reaction Name: p14-ARF transcription is stimulated by RUNX proteins
See in Reactome
R-HSA-1234167
(
R-HSA-1234158
)
R-HSA-1234167
Reaction Name: Formation of HIF:CBP:p300 complex at promoters
See in Reactome
R-HSA-9617758
(
R-HSA-9617629
)
R-HSA-9038163
(
R-HSA-9018519
)
R-HSA-9038163
Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
See in Reactome
R-HSA-9016751
(
R-HSA-9013508
)
R-HSA-9016751
Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3
See in Reactome
R-HSA-6782211
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782211
Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site
See in Reactome
R-HSA-560498
(
R-HSA-381340
)
R-HSA-560498
Reaction Name: Expression of Lipoprotein lipase (LPL)
See in Reactome
R-HSA-1980065
(
R-HSA-2122947
)
R-HSA-1980065
Reaction Name: NOTCH1 stimulates HEY transcription
See in Reactome
R-HSA-9759332
()
R-HSA-9759332
Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter
See in Reactome
R-HSA-9613451
(
R-HSA-9031628
)
R-HSA-9613451
Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
See in Reactome
R-HSA-8936621
(
R-HSA-8936459
)
R-HSA-8936621
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
See in Reactome
R-HSA-5628871
(
R-HSA-6804758
)
R-HSA-5628871
Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53
See in Reactome
R-HSA-1980067
(
R-HSA-2122947
)
R-HSA-1980067
Reaction Name: NOTCH1 stimulates MYC transcription
See in Reactome
R-HSA-9620723
(
R-HSA-9031628
)
R-HSA-5250938
(
R-HSA-5250924
)
R-HSA-5250938
Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
See in Reactome
R-HSA-6782204
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782204
Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
See in Reactome
R-HSA-5617867
(
R-HSA-5617472
)
R-HSA-9761849
()
R-HSA-9761849
Reaction Name: AcK-NFE2L2-dependent P6GD gene expression
See in Reactome
R-HSA-9023884
(
R-HSA-9018519
)
R-HSA-9023884
Reaction Name: NCOA1 recruits EP300 to TGFA promoter
See in Reactome
R-HSA-8937050
(
R-HSA-8936459
)
R-HSA-8937050
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
See in Reactome
R-HSA-8952081
(
R-HSA-8951936
)
R-HSA-8952081
Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
See in Reactome
R-HSA-3662335
(
R-HSA-3214847
)
R-HSA-3662335
Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4
See in Reactome
R-HSA-1183003
(
R-HSA-381340
)
R-HSA-6804379
(
R-HSA-6804760
)
R-HSA-4088162
(
R-HSA-156711
)
R-HSA-3134883
(
R-HSA-3134973
)
R-HSA-3134883
Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300
See in Reactome
R-HSA-381309
(
R-HSA-381340
)
R-HSA-381309
Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands
See in Reactome
R-HSA-9023846
(
R-HSA-9018519
)
R-HSA-9023846
Reaction Name: Estrogen-responsive CTSD expression
See in Reactome
R-HSA-1028820
(
R-HSA-933541
)
R-HSA-1028820
Reaction Name: Formation of VAF (virus-activated factor) complex
See in Reactome
R-HSA-8878243
(
R-HSA-8941856
)
R-HSA-8878243
Reaction Name: HES1 gene transcription is inhibited by RUNX3
See in Reactome
R-HSA-9021450
(
R-HSA-9013508
)
R-HSA-9021450
Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes
See in Reactome
R-HSA-9761828
()
R-HSA-1028817
(
R-HSA-918233
)
R-HSA-1028817
Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3
See in Reactome
R-HSA-9008315
(
R-HSA-9018519
)
R-HSA-9008315
Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen
See in Reactome
R-HSA-8936628
(
R-HSA-8936459
)
R-HSA-8936628
Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9023860
(
R-HSA-9018519
)
R-HSA-9023860
Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene
See in Reactome
R-HSA-9761846
()
R-HSA-9761846
Reaction Name: NFE2L2-dependent PGD gene expression
See in Reactome
R-HSA-8936481
(
R-HSA-8936459
)
R-HSA-8936481
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
See in Reactome
R-HSA-5663264
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-6805650
(
R-HSA-6804758
)
R-HSA-6805650
Reaction Name: MTA2-NuRD complex deacetylates TP53
See in Reactome
R-HSA-5617452
(
R-HSA-5617472
)
R-HSA-5617452
Reaction Name: Retinoic acid activates HOXB1 chromatin
See in Reactome
R-HSA-4396347
(
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-4396347
Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter
See in Reactome
R-HSA-9759141
()
R-HSA-9759141
Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene
See in Reactome
R-HSA-9760125
()
R-HSA-9760125
Reaction Name: AcK-NFE2L2-dependent GCLM gene expression
See in Reactome
R-HSA-9613460
(
R-HSA-9031628
)
R-HSA-9620717
(
R-HSA-9031628
)
R-HSA-9620717
Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter
See in Reactome
R-HSA-8951951
(
R-HSA-8951936
)
R-HSA-9029561
(
R-HSA-9029569
)
R-HSA-9029561
Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter
See in Reactome
R-HSA-560473
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-9622604
(
R-HSA-9614657
)
R-HSA-9622604
Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y
See in Reactome
R-HSA-9617064
(
R-HSA-9616222
)
R-HSA-9617064
Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
See in Reactome
R-HSA-9008285
(
R-HSA-9018519
)
R-HSA-9008285
Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
See in Reactome
R-HSA-3371554
(
R-HSA-3371568
)
R-HSA-9701531
(
R-HSA-9701898
)
R-HSA-9701531
Reaction Name: p-Y705,S727 STAT3 is acetylated
See in Reactome
R-HSA-9017835
(
R-HSA-1912408
)
R-HSA-9017835
Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene
See in Reactome
R-HSA-8937097
(
R-HSA-8936459
)
R-HSA-8937097
Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-8936616
(
R-HSA-8936459
)
R-HSA-8936616
Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene
See in Reactome
R-HSA-5663246
(
R-HSA-400253
)
R-HSA-6804229
(
R-HSA-6804760
)
R-HSA-1801587
(
R-HSA-1368082;
R-HSA-1989781;
R-HSA-400253
)
R-HSA-8878056
(
R-HSA-8939243
)
R-HSA-9761812
()
R-HSA-9761812
Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
See in Reactome
R-HSA-4396382
(
R-HSA-2122947
)
R-HSA-4396382
Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes
See in Reactome
R-HSA-5617454
(
R-HSA-5617472
)
R-HSA-560510
(
R-HSA-381340
)
R-HSA-9760097
()
R-HSA-9760097
Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene
See in Reactome
R-HSA-6782004
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782004
Reaction Name: Assembly of the pre-incision complex in TC-NER
See in Reactome
R-HSA-5250930
(
R-HSA-5250924
)
R-HSA-5250930
Reaction Name: B-WICH recruits histone acetyltransferases
See in Reactome
R-HSA-8937016
(
R-HSA-8936459
)
R-HSA-8937016
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
See in Reactome
R-HSA-400342
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-6782138
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782138
Reaction Name: ERCC5 and RPA bind TC-NER site
See in Reactome
R-HSA-5617859
(
R-HSA-5617472
)
R-HSA-5617859
Reaction Name: Retinoic acid activates HOXB4 chromatin
See in Reactome
R-HSA-8952058
(
R-HSA-8951936
)
R-HSA-8952058
Reaction Name: CCND1 binds RUNX3 and displaces EP300
See in Reactome
R-HSA-1980047
(
R-HSA-210744;
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-1980047
Reaction Name: NOTCH1 stimulates HES1 transcription
See in Reactome
R-HSA-1235037
(
R-HSA-1234158
)
R-HSA-8878237
(
R-HSA-8941856
)
R-HSA-8878237
Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter
See in Reactome
R-HSA-9622579
(
R-HSA-9614657
)
R-HSA-9622579
Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter
See in Reactome
R-HSA-9620515
(
R-HSA-9617629
)
R-HSA-9620515
Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress
See in Reactome
R-HSA-933536
(
R-HSA-933541
)
R-HSA-933536
Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300
See in Reactome
R-HSA-9760128
()
R-HSA-9760128
Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression
See in Reactome
R-HSA-9617683
(
R-HSA-9617629
)
R-HSA-9617683
Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4
See in Reactome
R-HSA-1912415
(
R-HSA-1912408
)
R-HSA-1028812
(
R-HSA-918233
)
R-HSA-5693644
(
R-HSA-5617472
)
R-HSA-5693644
Reaction Name: HOXB1 maintains activation of HOXB1 chromatin
See in Reactome
R-HSA-9760082
()
R-HSA-1912394
(
R-HSA-2122947
)
R-HSA-1912394
Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML
See in Reactome
R-HSA-560493
(
R-HSA-381340
)
R-HSA-5617862
(
R-HSA-5617472
)
R-HSA-5617862
Reaction Name: Retinoic acid activates HOXA4 chromatin
See in Reactome
R-HSA-560517
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-560517
Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT)
See in Reactome
R-HSA-1912393
(
R-HSA-2122947
)
R-HSA-1912393
Reaction Name: MAML in complex with NICD1 recruits CDK8
See in Reactome
R-HSA-8935731
(
R-HSA-8936459
)
R-HSA-8935731
Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-6782208
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782208
Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
See in Reactome
R-HSA-5663293
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-1028819
(
R-HSA-933541
)
R-HSA-1028819
Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes
See in Reactome
R-HSA-5660666
(
R-HSA-5621575
)
R-HSA-5660666
Reaction Name: CBP and p300 binds NF-kB complex
See in Reactome
R-HSA-1912416
(
R-HSA-1912408
)
R-HSA-1912391
(
R-HSA-2122947
)
R-HSA-1912391
Reaction Name: NICD1 is phosphorylated by CDK8
See in Reactome
R-HSA-9761815
()
R-HSA-9761815
Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene
See in Reactome
R-HSA-549475
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-9760122
()
R-HSA-9760122
Reaction Name: AcK-NFE2L2-dependent GCLC gene expression
See in Reactome
R-HSA-6782227
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782227
Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER
See in Reactome
R-HSA-6811508
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-6811508
Reaction Name: ING2-bound EP300 acetylates TP53
See in Reactome
R-HSA-1235035
(
R-HSA-1234158
)
R-HSA-1235035
Reaction Name: Expression of Carbonic Anhydrase IX (CA9)
See in Reactome
R-HSA-9021451
(
R-HSA-9013508
)
R-HSA-9021451
Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter
See in Reactome
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9023840
(
R-HSA-9018519
)
R-HSA-9023840
Reaction Name: HATs and coactivators are recruited to the CTSD gene
See in Reactome
R-HSA-6811479
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-5617877
(
R-HSA-5617472
)
R-HSA-8864307
(
R-HSA-8866907
)
R-HSA-8864307
Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
See in Reactome
R-HSA-1028815
(
R-HSA-918233
)
R-HSA-1028815
Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta
See in Reactome
R-HSA-6804383
(
R-HSA-6804760
)
R-HSA-6782234
(
R-HSA-6781827
)
R-HSA-6782234
Reaction Name: Recovery of RNA synthesis after TC-NER
See in Reactome
R-HSA-9011975
(
R-HSA-9018519
)
R-HSA-9011975
Reaction Name: Estrogen-responsive MYC gene expression
See in Reactome
R-HSA-8878220
(
R-HSA-8941856
)
R-HSA-8878220
Reaction Name: RUNX3 binds the NOTCH1 coactivator complex
See in Reactome
R-HSA-2976551
(
R-HSA-2197563
)
R-HSA-2976551
Reaction Name: NOTCH2 stimulates GZMB transcription
See in Reactome
R-HSA-1368081
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-5617431
(
R-HSA-5617472
)
R-HSA-5617431
Reaction Name: Retinoic acid activates HOXA1 chromatin
See in Reactome
R-HSA-1980078
(
R-HSA-2122947
)
R-HSA-1980078
Reaction Name: NOTCH1 stimulates HES5 transcription
See in Reactome
R-HSA-4396379
(
R-HSA-2122947
)
R-HSA-4396379
Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter
See in Reactome
R-HSA-3215152
(
R-HSA-6804114
)
R-HSA-3215152
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
See in Reactome
R-HSA-4088152
(
R-HSA-156711
)
R-HSA-4088152
Reaction Name: FOXM1 stimulates CDC25A transcription
See in Reactome
R-HSA-9009371
(
R-HSA-9018519
)
R-HSA-9009371
Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter
See in Reactome
R-HSA-9023859
(
R-HSA-9018519
)
R-HSA-9023859
Reaction Name: Estrogen-responsive TFF1 gene expression
See in Reactome
R-HSA-1368087
(
R-HSA-400253
)
R-HSA-1368087
Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene
See in Reactome
R-HSA-1368065
(
R-HSA-1989781;
R-HSA-400253;
R-HSA-9707616
)
R-HSA-1183058
(
R-HSA-381340
)
R-HSA-9622572
(
R-HSA-9614657
)
R-HSA-9622572
Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
See in Reactome
R-HSA-3899291
(
R-HSA-3899300
)
R-HSA-3899291
Reaction Name: SUMOylation of EP300 with SUMO1
See in Reactome
R-HSA-9634433
(
R-HSA-9616222
)
R-HSA-9634433
Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid
See in Reactome
R-HSA-9605057
(
R-HSA-9029569
)
R-HSA-9605057
Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3
See in Reactome
R-HSA-5617471
(
R-HSA-5617472
)
R-HSA-9761841
()
R-HSA-9761841
Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression
See in Reactome
R-HSA-5691381
(
R-HSA-5689901
)
R-HSA-5691381
Reaction Name: MYSM1 deubiquitinates Histone H2A
See in Reactome
R-HSA-5617874
(
R-HSA-5617472
)
R-HSA-9760099
()
R-HSA-9760099
Reaction Name: AcK-NFE2L2 binds the GCLC gene
See in Reactome
R-HSA-9018499
(
R-HSA-9018519
)
R-HSA-9018499
Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter
See in Reactome
R-HSA-9760103
()
R-HSA-9760103
Reaction Name: AcK-NFE2L2 binds the GCLM gene
See in Reactome
R-HSA-560472
(
R-HSA-381340
)
R-HSA-560472
Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
See in Reactome
R-HSA-6782131
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782131
Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-8935740
(
R-HSA-8936459
)
R-HSA-8935740
Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene
See in Reactome
R-HSA-9009378
(
R-HSA-9018519
)
R-HSA-9009378
Reaction Name: Estrogen-responsive CCND1 gene expression
See in Reactome
R-HSA-8952419
(
R-HSA-8941858
)
R-HSA-6782224
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782224
Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER
See in Reactome
R-HSA-8936979
(
R-HSA-8936459
)
R-HSA-8936979
Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene
See in Reactome
R-HSA-1235070
(
R-HSA-1234158
)
R-HSA-1235070
Reaction Name: Expression of Erythropoietin (EPO)
See in Reactome
R-HSA-5660660
(
R-HSA-5621575
)
R-HSA-3215144
(
R-HSA-6804114
)
R-HSA-3215144
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription
See in Reactome
R-HSA-8951966
(
R-HSA-8951936
)
R-HSA-9008271
(
R-HSA-9018519
)
R-HSA-9008271
Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
See in Reactome
R-HSA-9011941
(
R-HSA-9018519
)
R-HSA-9011941
Reaction Name: Estrogen-responsive BCL2 gene expression
See in Reactome
R-HSA-2976563
(
R-HSA-2197563
)
R-HSA-2976563
Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
See in Reactome
R-HSA-5663273
(
R-HSA-400253
)
R-HSA-5663273
Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene
See in Reactome
R-HSA-9604499
(
R-HSA-933541
)
R-HSA-9604499
Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300
See in Reactome
R-HSA-9604664
(
R-HSA-9013695
)
R-HSA-9604664
Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
See in Reactome
R-HSA-6782141
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782141
Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
See in Reactome
R-HSA-5617896
(
R-HSA-5617472
)
R-HSA-5617896
Reaction Name: Retinoic acid activates HOXD4 chromatin
See in Reactome
R-HSA-8937037
(
R-HSA-8936459
)
R-HSA-8937037
Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene
See in Reactome
R-HSA-9759364
()
R-HSA-9759364
Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression
See in Reactome
R-HSA-9617735
(
R-HSA-9617629
)
R-HSA-9617735
Reaction Name: TXN disrupts FOXO4 complex with EP300
See in Reactome
R-HSA-3322427
(
R-HSA-201722
)
R-HSA-3322427
Reaction Name: Beta-catenin recruits CBP/p300
See in Reactome
R-HSA-9018497
(
R-HSA-9018519
)
R-HSA-9018497
Reaction Name: Estrogen-responsive TFF3 gene expression
See in Reactome
R-HSA-8936995
(
R-HSA-8936459
)
R-HSA-8936995
Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9684118
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-9684118
Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-6804242
(
R-HSA-6804760
)
R-HSA-6804242
Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5
See in Reactome
R-HSA-9759186
()
R-HSA-9759186
Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression
See in Reactome
R-HSA-3222093
(
R-HSA-6804758
)
|
MONDO:0013767 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0014112 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0015278 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0015447 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0016419 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0016692 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0016982 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0018874 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0019086 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0019086 |
EP300 |
Q09472 |
2.3.1.-
2.3.1.48
|
R-HSA-9617629
R-HSA-9617629
Reactome Name: Regulation of FOXO transcriptional activity by acetylation
See in Reactome
R-HSA-210744
R-HSA-210744
Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
See in Reactome
R-HSA-5689901
R-HSA-6804760
R-HSA-6804760
Reactome Name: Regulation of TP53 Activity through Methylation
See in Reactome
R-HSA-8939243
R-HSA-8939243
Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
See in Reactome
R-HSA-381340
R-HSA-381340
Reactome Name: Transcriptional regulation of white adipocyte differentiation
See in Reactome
R-HSA-9616222
R-HSA-9616222
Reactome Name: Transcriptional regulation of granulopoiesis
See in Reactome
R-HSA-9013695
R-HSA-9013695
Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-6782135
R-HSA-6782210
R-HSA-6782210
Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER
See in Reactome
R-HSA-8941856
R-HSA-8941856
Reactome Name: RUNX3 regulates NOTCH signaling
See in Reactome
R-HSA-8941858
R-HSA-8941858
Reactome Name: Regulation of RUNX3 expression and activity
See in Reactome
R-HSA-6804114
R-HSA-6804114
Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
See in Reactome
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-918233
R-HSA-918233
Reactome Name: TRAF3-dependent IRF activation pathway
See in Reactome
R-HSA-6781827
R-HSA-6781827
Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
See in Reactome
R-HSA-156711
R-HSA-156711
Reactome Name: Polo-like kinase mediated events
See in Reactome
R-HSA-5250924
R-HSA-5250924
Reactome Name: B-WICH complex positively regulates rRNA expression
See in Reactome
R-HSA-6781823
R-HSA-6781823
Reactome Name: Formation of TC-NER Pre-Incision Complex
See in Reactome
R-HSA-9013508
R-HSA-9013508
Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-3214847
R-HSA-3371568
R-HSA-8866907
R-HSA-8866907
Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors
See in Reactome
R-HSA-9614657
R-HSA-9614657
Reactome Name: FOXO-mediated transcription of cell death genes
See in Reactome
R-HSA-9701898
R-HSA-9701898
Reactome Name: STAT3 nuclear events downstream of ALK signaling
See in Reactome
R-HSA-933541
R-HSA-1234158
R-HSA-1234158
Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor
See in Reactome
R-HSA-1368082
R-HSA-1368082
Reactome Name: RORA activates gene expression
See in Reactome
R-HSA-5617472
R-HSA-5617472
Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis
See in Reactome
R-HSA-3899300
R-HSA-3899300
Reactome Name: SUMOylation of transcription cofactors
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8936459
R-HSA-8936459
Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-2197563
R-HSA-2197563
Reactome Name: NOTCH2 intracellular domain regulates transcription
See in Reactome
R-HSA-400253
R-HSA-9707616
R-HSA-3134973
R-HSA-3134973
Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
See in Reactome
R-HSA-201722
R-HSA-201722
Reactome Name: Formation of the beta-catenin:TCF transactivating complex
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8951936
R-HSA-5621575
R-HSA-9031628
R-HSA-6811555
R-HSA-6811555
Reactome Name: PI5P Regulates TP53 Acetylation
See in Reactome
R-HSA-6804758
R-HSA-6804758
Reactome Name: Regulation of TP53 Activity through Acetylation
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-9012852
R-HSA-5633007
R-HSA-168256
R-HSA-9013694
R-HSA-168928
R-HSA-168928
Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta
See in Reactome
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-6791312
R-HSA-6791312
Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-1430728
R-HSA-8864260
R-HSA-8864260
Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-2262752
R-HSA-73894
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-2990846
R-HSA-556833
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-8953897
R-HSA-212165
R-HSA-212165
Reactome Name: Epigenetic regulation of gene expression
See in Reactome
R-HSA-5696398
R-HSA-168249
R-HSA-453274
R-HSA-392499
R-HSA-1234174
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-1980143
R-HSA-8939211
R-HSA-1834949
R-HSA-1834949
Reactome Name: Cytosolic sensors of pathogen-associated DNA
See in Reactome
R-HSA-186712
R-HSA-186712
Reactome Name: Regulation of beta-cell development
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-157118
R-HSA-187037
R-HSA-3247509
R-HSA-195721
R-HSA-1980145
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9614085
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-5688426
R-HSA-201556
R-HSA-5250913
R-HSA-5250913
Reactome Name: Positive epigenetic regulation of rRNA expression
See in Reactome
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-4839726
R-HSA-69275
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-162582
R-HSA-5619507
R-HSA-5619507
Reactome Name: Activation of HOX genes during differentiation
See in Reactome
|
Circadian Clock
Immune System
Cell Cycle
Developmental Biology
Metabolism
Gene expression (Transcription)
DNA Repair
Cellular responses to stimuli
Metabolism of proteins
Chromatin organization
Signal Transduction
|
R-HSA-6782069
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782069
Reaction Name: UVSSA:USP7 deubiquitinates ERCC6
See in Reactome
R-HSA-9760081
()
R-HSA-9760081
Reaction Name: CREBBP, EP300 acetylates NFE2L2
See in Reactome
R-HSA-9011981
(
R-HSA-9018519
)
R-HSA-9011981
Reaction Name: EP300 is recruited to MYC and BCL2 genes
See in Reactome
R-HSA-8878050
(
R-HSA-8939243
)
R-HSA-8878050
Reaction Name: HIPK2 phosphorylates RUNX1 and EP300
See in Reactome
R-HSA-9761836
()
R-HSA-9761836
Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300
See in Reactome
R-HSA-560491
(
R-HSA-381340
)
R-HSA-4396371
(
R-HSA-2122947
)
R-HSA-4396371
Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter
See in Reactome
R-HSA-9038052
(
R-HSA-9018519
)
R-HSA-9038052
Reaction Name: GREB1 binds ESR1:ESTG and co-activators
See in Reactome
R-HSA-8952101
(
R-HSA-8951936
)
R-HSA-8952101
Reaction Name: p14-ARF transcription is stimulated by RUNX proteins
See in Reactome
R-HSA-1234167
(
R-HSA-1234158
)
R-HSA-1234167
Reaction Name: Formation of HIF:CBP:p300 complex at promoters
See in Reactome
R-HSA-9617758
(
R-HSA-9617629
)
R-HSA-9038163
(
R-HSA-9018519
)
R-HSA-9038163
Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
See in Reactome
R-HSA-9016751
(
R-HSA-9013508
)
R-HSA-9016751
Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3
See in Reactome
R-HSA-6782211
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782211
Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site
See in Reactome
R-HSA-560498
(
R-HSA-381340
)
R-HSA-560498
Reaction Name: Expression of Lipoprotein lipase (LPL)
See in Reactome
R-HSA-1980065
(
R-HSA-2122947
)
R-HSA-1980065
Reaction Name: NOTCH1 stimulates HEY transcription
See in Reactome
R-HSA-9759332
()
R-HSA-9759332
Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter
See in Reactome
R-HSA-9613451
(
R-HSA-9031628
)
R-HSA-9613451
Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
See in Reactome
R-HSA-8936621
(
R-HSA-8936459
)
R-HSA-8936621
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
See in Reactome
R-HSA-5628871
(
R-HSA-6804758
)
R-HSA-5628871
Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53
See in Reactome
R-HSA-1980067
(
R-HSA-2122947
)
R-HSA-1980067
Reaction Name: NOTCH1 stimulates MYC transcription
See in Reactome
R-HSA-9620723
(
R-HSA-9031628
)
R-HSA-5250938
(
R-HSA-5250924
)
R-HSA-5250938
Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
See in Reactome
R-HSA-6782204
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782204
Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
See in Reactome
R-HSA-5617867
(
R-HSA-5617472
)
R-HSA-9761849
()
R-HSA-9761849
Reaction Name: AcK-NFE2L2-dependent P6GD gene expression
See in Reactome
R-HSA-9023884
(
R-HSA-9018519
)
R-HSA-9023884
Reaction Name: NCOA1 recruits EP300 to TGFA promoter
See in Reactome
R-HSA-8937050
(
R-HSA-8936459
)
R-HSA-8937050
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
See in Reactome
R-HSA-8952081
(
R-HSA-8951936
)
R-HSA-8952081
Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
See in Reactome
R-HSA-3662335
(
R-HSA-3214847
)
R-HSA-3662335
Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4
See in Reactome
R-HSA-1183003
(
R-HSA-381340
)
R-HSA-6804379
(
R-HSA-6804760
)
R-HSA-4088162
(
R-HSA-156711
)
R-HSA-3134883
(
R-HSA-3134973
)
R-HSA-3134883
Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300
See in Reactome
R-HSA-381309
(
R-HSA-381340
)
R-HSA-381309
Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands
See in Reactome
R-HSA-9023846
(
R-HSA-9018519
)
R-HSA-9023846
Reaction Name: Estrogen-responsive CTSD expression
See in Reactome
R-HSA-1028820
(
R-HSA-933541
)
R-HSA-1028820
Reaction Name: Formation of VAF (virus-activated factor) complex
See in Reactome
R-HSA-8878243
(
R-HSA-8941856
)
R-HSA-8878243
Reaction Name: HES1 gene transcription is inhibited by RUNX3
See in Reactome
R-HSA-9021450
(
R-HSA-9013508
)
R-HSA-9021450
Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes
See in Reactome
R-HSA-9761828
()
R-HSA-1028817
(
R-HSA-918233
)
R-HSA-1028817
Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3
See in Reactome
R-HSA-9008315
(
R-HSA-9018519
)
R-HSA-9008315
Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen
See in Reactome
R-HSA-8936628
(
R-HSA-8936459
)
R-HSA-8936628
Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9023860
(
R-HSA-9018519
)
R-HSA-9023860
Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene
See in Reactome
R-HSA-9761846
()
R-HSA-9761846
Reaction Name: NFE2L2-dependent PGD gene expression
See in Reactome
R-HSA-8936481
(
R-HSA-8936459
)
R-HSA-8936481
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
See in Reactome
R-HSA-5663264
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-6805650
(
R-HSA-6804758
)
R-HSA-6805650
Reaction Name: MTA2-NuRD complex deacetylates TP53
See in Reactome
R-HSA-5617452
(
R-HSA-5617472
)
R-HSA-5617452
Reaction Name: Retinoic acid activates HOXB1 chromatin
See in Reactome
R-HSA-4396347
(
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-4396347
Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter
See in Reactome
R-HSA-9759141
()
R-HSA-9759141
Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene
See in Reactome
R-HSA-9760125
()
R-HSA-9760125
Reaction Name: AcK-NFE2L2-dependent GCLM gene expression
See in Reactome
R-HSA-9613460
(
R-HSA-9031628
)
R-HSA-9620717
(
R-HSA-9031628
)
R-HSA-9620717
Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter
See in Reactome
R-HSA-8951951
(
R-HSA-8951936
)
R-HSA-9029561
(
R-HSA-9029569
)
R-HSA-9029561
Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter
See in Reactome
R-HSA-560473
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-9622604
(
R-HSA-9614657
)
R-HSA-9622604
Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y
See in Reactome
R-HSA-9617064
(
R-HSA-9616222
)
R-HSA-9617064
Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
See in Reactome
R-HSA-9008285
(
R-HSA-9018519
)
R-HSA-9008285
Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
See in Reactome
R-HSA-3371554
(
R-HSA-3371568
)
R-HSA-9701531
(
R-HSA-9701898
)
R-HSA-9701531
Reaction Name: p-Y705,S727 STAT3 is acetylated
See in Reactome
R-HSA-9017835
(
R-HSA-1912408
)
R-HSA-9017835
Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene
See in Reactome
R-HSA-8937097
(
R-HSA-8936459
)
R-HSA-8937097
Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-8936616
(
R-HSA-8936459
)
R-HSA-8936616
Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene
See in Reactome
R-HSA-5663246
(
R-HSA-400253
)
R-HSA-6804229
(
R-HSA-6804760
)
R-HSA-1801587
(
R-HSA-1368082;
R-HSA-1989781;
R-HSA-400253
)
R-HSA-8878056
(
R-HSA-8939243
)
R-HSA-9761812
()
R-HSA-9761812
Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
See in Reactome
R-HSA-4396382
(
R-HSA-2122947
)
R-HSA-4396382
Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes
See in Reactome
R-HSA-5617454
(
R-HSA-5617472
)
R-HSA-560510
(
R-HSA-381340
)
R-HSA-9760097
()
R-HSA-9760097
Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene
See in Reactome
R-HSA-6782004
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782004
Reaction Name: Assembly of the pre-incision complex in TC-NER
See in Reactome
R-HSA-5250930
(
R-HSA-5250924
)
R-HSA-5250930
Reaction Name: B-WICH recruits histone acetyltransferases
See in Reactome
R-HSA-8937016
(
R-HSA-8936459
)
R-HSA-8937016
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
See in Reactome
R-HSA-400342
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-6782138
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782138
Reaction Name: ERCC5 and RPA bind TC-NER site
See in Reactome
R-HSA-5617859
(
R-HSA-5617472
)
R-HSA-5617859
Reaction Name: Retinoic acid activates HOXB4 chromatin
See in Reactome
R-HSA-8952058
(
R-HSA-8951936
)
R-HSA-8952058
Reaction Name: CCND1 binds RUNX3 and displaces EP300
See in Reactome
R-HSA-1980047
(
R-HSA-210744;
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-1980047
Reaction Name: NOTCH1 stimulates HES1 transcription
See in Reactome
R-HSA-1235037
(
R-HSA-1234158
)
R-HSA-8878237
(
R-HSA-8941856
)
R-HSA-8878237
Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter
See in Reactome
R-HSA-9622579
(
R-HSA-9614657
)
R-HSA-9622579
Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter
See in Reactome
R-HSA-9620515
(
R-HSA-9617629
)
R-HSA-9620515
Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress
See in Reactome
R-HSA-933536
(
R-HSA-933541
)
R-HSA-933536
Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300
See in Reactome
R-HSA-9760128
()
R-HSA-9760128
Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression
See in Reactome
R-HSA-9617683
(
R-HSA-9617629
)
R-HSA-9617683
Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4
See in Reactome
R-HSA-1912415
(
R-HSA-1912408
)
R-HSA-1028812
(
R-HSA-918233
)
R-HSA-5693644
(
R-HSA-5617472
)
R-HSA-5693644
Reaction Name: HOXB1 maintains activation of HOXB1 chromatin
See in Reactome
R-HSA-9760082
()
R-HSA-1912394
(
R-HSA-2122947
)
R-HSA-1912394
Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML
See in Reactome
R-HSA-560493
(
R-HSA-381340
)
R-HSA-5617862
(
R-HSA-5617472
)
R-HSA-5617862
Reaction Name: Retinoic acid activates HOXA4 chromatin
See in Reactome
R-HSA-560517
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-560517
Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT)
See in Reactome
R-HSA-1912393
(
R-HSA-2122947
)
R-HSA-1912393
Reaction Name: MAML in complex with NICD1 recruits CDK8
See in Reactome
R-HSA-8935731
(
R-HSA-8936459
)
R-HSA-8935731
Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-6782208
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782208
Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
See in Reactome
R-HSA-5663293
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-1028819
(
R-HSA-933541
)
R-HSA-1028819
Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes
See in Reactome
R-HSA-5660666
(
R-HSA-5621575
)
R-HSA-5660666
Reaction Name: CBP and p300 binds NF-kB complex
See in Reactome
R-HSA-1912416
(
R-HSA-1912408
)
R-HSA-1912391
(
R-HSA-2122947
)
R-HSA-1912391
Reaction Name: NICD1 is phosphorylated by CDK8
See in Reactome
R-HSA-9761815
()
R-HSA-9761815
Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene
See in Reactome
R-HSA-549475
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-9760122
()
R-HSA-9760122
Reaction Name: AcK-NFE2L2-dependent GCLC gene expression
See in Reactome
R-HSA-6782227
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782227
Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER
See in Reactome
R-HSA-6811508
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-6811508
Reaction Name: ING2-bound EP300 acetylates TP53
See in Reactome
R-HSA-1235035
(
R-HSA-1234158
)
R-HSA-1235035
Reaction Name: Expression of Carbonic Anhydrase IX (CA9)
See in Reactome
R-HSA-9021451
(
R-HSA-9013508
)
R-HSA-9021451
Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter
See in Reactome
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9023840
(
R-HSA-9018519
)
R-HSA-9023840
Reaction Name: HATs and coactivators are recruited to the CTSD gene
See in Reactome
R-HSA-6811479
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-5617877
(
R-HSA-5617472
)
R-HSA-8864307
(
R-HSA-8866907
)
R-HSA-8864307
Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
See in Reactome
R-HSA-1028815
(
R-HSA-918233
)
R-HSA-1028815
Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta
See in Reactome
R-HSA-6804383
(
R-HSA-6804760
)
R-HSA-6782234
(
R-HSA-6781827
)
R-HSA-6782234
Reaction Name: Recovery of RNA synthesis after TC-NER
See in Reactome
R-HSA-9011975
(
R-HSA-9018519
)
R-HSA-9011975
Reaction Name: Estrogen-responsive MYC gene expression
See in Reactome
R-HSA-8878220
(
R-HSA-8941856
)
R-HSA-8878220
Reaction Name: RUNX3 binds the NOTCH1 coactivator complex
See in Reactome
R-HSA-2976551
(
R-HSA-2197563
)
R-HSA-2976551
Reaction Name: NOTCH2 stimulates GZMB transcription
See in Reactome
R-HSA-1368081
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-5617431
(
R-HSA-5617472
)
R-HSA-5617431
Reaction Name: Retinoic acid activates HOXA1 chromatin
See in Reactome
R-HSA-1980078
(
R-HSA-2122947
)
R-HSA-1980078
Reaction Name: NOTCH1 stimulates HES5 transcription
See in Reactome
R-HSA-4396379
(
R-HSA-2122947
)
R-HSA-4396379
Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter
See in Reactome
R-HSA-3215152
(
R-HSA-6804114
)
R-HSA-3215152
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
See in Reactome
R-HSA-4088152
(
R-HSA-156711
)
R-HSA-4088152
Reaction Name: FOXM1 stimulates CDC25A transcription
See in Reactome
R-HSA-9009371
(
R-HSA-9018519
)
R-HSA-9009371
Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter
See in Reactome
R-HSA-9023859
(
R-HSA-9018519
)
R-HSA-9023859
Reaction Name: Estrogen-responsive TFF1 gene expression
See in Reactome
R-HSA-1368087
(
R-HSA-400253
)
R-HSA-1368087
Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene
See in Reactome
R-HSA-1368065
(
R-HSA-1989781;
R-HSA-400253;
R-HSA-9707616
)
R-HSA-1183058
(
R-HSA-381340
)
R-HSA-9622572
(
R-HSA-9614657
)
R-HSA-9622572
Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
See in Reactome
R-HSA-3899291
(
R-HSA-3899300
)
R-HSA-3899291
Reaction Name: SUMOylation of EP300 with SUMO1
See in Reactome
R-HSA-9634433
(
R-HSA-9616222
)
R-HSA-9634433
Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid
See in Reactome
R-HSA-9605057
(
R-HSA-9029569
)
R-HSA-9605057
Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3
See in Reactome
R-HSA-5617471
(
R-HSA-5617472
)
R-HSA-9761841
()
R-HSA-9761841
Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression
See in Reactome
R-HSA-5691381
(
R-HSA-5689901
)
R-HSA-5691381
Reaction Name: MYSM1 deubiquitinates Histone H2A
See in Reactome
R-HSA-5617874
(
R-HSA-5617472
)
R-HSA-9760099
()
R-HSA-9760099
Reaction Name: AcK-NFE2L2 binds the GCLC gene
See in Reactome
R-HSA-9018499
(
R-HSA-9018519
)
R-HSA-9018499
Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter
See in Reactome
R-HSA-9760103
()
R-HSA-9760103
Reaction Name: AcK-NFE2L2 binds the GCLM gene
See in Reactome
R-HSA-560472
(
R-HSA-381340
)
R-HSA-560472
Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
See in Reactome
R-HSA-6782131
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782131
Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-8935740
(
R-HSA-8936459
)
R-HSA-8935740
Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene
See in Reactome
R-HSA-9009378
(
R-HSA-9018519
)
R-HSA-9009378
Reaction Name: Estrogen-responsive CCND1 gene expression
See in Reactome
R-HSA-8952419
(
R-HSA-8941858
)
R-HSA-6782224
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782224
Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER
See in Reactome
R-HSA-8936979
(
R-HSA-8936459
)
R-HSA-8936979
Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene
See in Reactome
R-HSA-1235070
(
R-HSA-1234158
)
R-HSA-1235070
Reaction Name: Expression of Erythropoietin (EPO)
See in Reactome
R-HSA-5660660
(
R-HSA-5621575
)
R-HSA-3215144
(
R-HSA-6804114
)
R-HSA-3215144
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription
See in Reactome
R-HSA-8951966
(
R-HSA-8951936
)
R-HSA-9008271
(
R-HSA-9018519
)
R-HSA-9008271
Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
See in Reactome
R-HSA-9011941
(
R-HSA-9018519
)
R-HSA-9011941
Reaction Name: Estrogen-responsive BCL2 gene expression
See in Reactome
R-HSA-2976563
(
R-HSA-2197563
)
R-HSA-2976563
Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
See in Reactome
R-HSA-5663273
(
R-HSA-400253
)
R-HSA-5663273
Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene
See in Reactome
R-HSA-9604499
(
R-HSA-933541
)
R-HSA-9604499
Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300
See in Reactome
R-HSA-9604664
(
R-HSA-9013695
)
R-HSA-9604664
Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
See in Reactome
R-HSA-6782141
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782141
Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
See in Reactome
R-HSA-5617896
(
R-HSA-5617472
)
R-HSA-5617896
Reaction Name: Retinoic acid activates HOXD4 chromatin
See in Reactome
R-HSA-8937037
(
R-HSA-8936459
)
R-HSA-8937037
Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene
See in Reactome
R-HSA-9759364
()
R-HSA-9759364
Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression
See in Reactome
R-HSA-9617735
(
R-HSA-9617629
)
R-HSA-9617735
Reaction Name: TXN disrupts FOXO4 complex with EP300
See in Reactome
R-HSA-3322427
(
R-HSA-201722
)
R-HSA-3322427
Reaction Name: Beta-catenin recruits CBP/p300
See in Reactome
R-HSA-9018497
(
R-HSA-9018519
)
R-HSA-9018497
Reaction Name: Estrogen-responsive TFF3 gene expression
See in Reactome
R-HSA-8936995
(
R-HSA-8936459
)
R-HSA-8936995
Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9684118
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-9684118
Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-6804242
(
R-HSA-6804760
)
R-HSA-6804242
Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5
See in Reactome
R-HSA-9759186
()
R-HSA-9759186
Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression
See in Reactome
R-HSA-3222093
(
R-HSA-6804758
)
|
MONDO:0019438 |
KRAS |
P01116 |
3.6.5.2
|
R-HSA-171007
R-HSA-2871796
R-HSA-2871796
Reactome Name: FCERI mediated MAPK activation
See in Reactome
R-HSA-9634635
R-HSA-9634635
Reactome Name: Estrogen-stimulated signaling through PRKCZ
See in Reactome
R-HSA-8951936
R-HSA-1963640
R-HSA-1963640
Reactome Name: GRB2 events in ERBB2 signaling
See in Reactome
R-HSA-5674135
R-HSA-9027284
R-HSA-9607240
R-HSA-8849471
R-HSA-8849471
Reactome Name: PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
See in Reactome
R-HSA-186763
R-HSA-442982
R-HSA-442982
Reactome Name: Ras activation upon Ca2+ influx through NMDA receptor
See in Reactome
R-HSA-5673000
R-HSA-5673001
R-HSA-9648002
R-HSA-9026519
R-HSA-9026519
Reactome Name: Activated NTRK2 signals through RAS
See in Reactome
R-HSA-5654688
R-HSA-9028731
R-HSA-9028731
Reactome Name: Activated NTRK2 signals through FRS2 and FRS3
See in Reactome
R-HSA-4086398
R-HSA-5654700
R-HSA-5654712
R-HSA-5654706
R-HSA-5654704
R-HSA-1169092
R-HSA-74751
R-HSA-74751
Reactome Name: Insulin receptor signalling cascade
See in Reactome
R-HSA-9034864
R-HSA-9034864
Reactome Name: Activated NTRK3 signals through RAS
See in Reactome
R-HSA-1433557
R-HSA-375165
R-HSA-375165
Reactome Name: NCAM signaling for neurite out-growth
See in Reactome
R-HSA-167044
R-HSA-2428933
R-HSA-2428933
Reactome Name: SHC-related events triggered by IGF1R
See in Reactome
R-HSA-2424491
R-HSA-180336
R-HSA-5654693
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-5658442
R-HSA-9674555
R-HSA-179812
R-HSA-1250347
R-HSA-1250347
Reactome Name: SHC1 events in ERBB4 signaling
See in Reactome
R-HSA-8851805
R-HSA-5621575
R-HSA-112412
R-HSA-210993
R-HSA-1250196
R-HSA-1250196
Reactome Name: SHC1 events in ERBB2 signaling
See in Reactome
R-HSA-2179392
R-HSA-2179392
Reactome Name: EGFR Transactivation by Gastrin
See in Reactome
R-HSA-5654719
R-HSA-5218921
R-HSA-5218921
Reactome Name: VEGFR2 mediated cell proliferation
See in Reactome
R-HSA-5654699
|
R-HSA-186797
R-HSA-8848021
R-HSA-2404192
R-HSA-2404192
Reactome Name: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
See in Reactome
R-HSA-168256
R-HSA-983705
R-HSA-983705
Reactome Name: Signaling by the B Cell Receptor (BCR)
See in Reactome
R-HSA-202733
R-HSA-202733
Reactome Name: Cell surface interactions at the vascular wall
See in Reactome
R-HSA-9006927
R-HSA-9006927
Reactome Name: Signaling by Non-Receptor Tyrosine Kinases
See in Reactome
R-HSA-2428924
R-HSA-438064
R-HSA-438064
Reactome Name: Post NMDA receptor activation events
See in Reactome
R-HSA-2428928
R-HSA-2428928
Reactome Name: IRS-related events triggered by IGF1R
See in Reactome
R-HSA-1236394
R-HSA-112399
R-HSA-74752
R-HSA-442742
R-HSA-442742
Reactome Name: CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-5654687
R-HSA-5654687
Reactome Name: Downstream signaling of activated FGFR1
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-881907
R-HSA-881907
Reactome Name: Gastrin-CREB signalling pathway via PKC and MAPK
See in Reactome
R-HSA-9675108
R-HSA-5684996
R-HSA-177929
R-HSA-1168372
R-HSA-1168372
Reactome Name: Downstream signaling events of B Cell Receptor (BCR)
See in Reactome
R-HSA-112316
R-HSA-5654708
R-HSA-5654708
Reactome Name: Downstream signaling of activated FGFR3
See in Reactome
R-HSA-112315
R-HSA-112315
Reactome Name: Transmission across Chemical Synapses
See in Reactome
R-HSA-5654743
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-4420097
R-HSA-9006335
R-HSA-190236
R-HSA-2454202
R-HSA-2454202
Reactome Name: Fc epsilon receptor (FCERI) signaling
See in Reactome
R-HSA-388396
R-HSA-3858494
R-HSA-3858494
Reactome Name: Beta-catenin independent WNT signaling
See in Reactome
R-HSA-9034015
R-HSA-168249
R-HSA-187687
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-8939211
R-HSA-9006115
R-HSA-442755
R-HSA-442755
Reactome Name: Activation of NMDA receptors and postsynaptic events
See in Reactome
R-HSA-5654696
R-HSA-5654696
Reactome Name: Downstream signaling of activated FGFR2
See in Reactome
R-HSA-9009391
R-HSA-9009391
Reactome Name: Extra-nuclear estrogen signaling
See in Reactome
R-HSA-112314
R-HSA-112314
Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission
See in Reactome
R-HSA-187037
R-HSA-1280218
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-6806834
R-HSA-195721
R-HSA-372790
R-HSA-5654738
R-HSA-5654736
R-HSA-416476
R-HSA-194138
R-HSA-2172127
R-HSA-5654716
R-HSA-5654716
Reactome Name: Downstream signaling of activated FGFR4
See in Reactome
R-HSA-1227986
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-422475
R-HSA-5654741
R-HSA-109582
R-HSA-162582
|
Immune System
Developmental Biology
Gene expression (Transcription)
Neuronal System
Hemostasis
Signal Transduction
|
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9647977
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647977
Reaction Name: ICMT methylates S-Farn RAS proteins
See in Reactome
R-HSA-9647978
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647978
Reaction Name: pro-RAS proteins are farnesylated
See in Reactome
R-HSA-9647999
(
R-HSA-5673001;
R-HSA-9648002
)
R-HSA-9647999
Reaction Name: RCE1 cleaves S-Farn proRAS proteins
See in Reactome
R-HSA-9674816
(
R-HSA-9674555
)
R-HSA-9674816
Reaction Name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS
See in Reactome
|
MONDO:0020769 |
EP300 |
Q09472 |
2.3.1.-
2.3.1.48
|
R-HSA-9617629
R-HSA-9617629
Reactome Name: Regulation of FOXO transcriptional activity by acetylation
See in Reactome
R-HSA-210744
R-HSA-210744
Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
See in Reactome
R-HSA-5689901
R-HSA-6804760
R-HSA-6804760
Reactome Name: Regulation of TP53 Activity through Methylation
See in Reactome
R-HSA-8939243
R-HSA-8939243
Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
See in Reactome
R-HSA-381340
R-HSA-381340
Reactome Name: Transcriptional regulation of white adipocyte differentiation
See in Reactome
R-HSA-9616222
R-HSA-9616222
Reactome Name: Transcriptional regulation of granulopoiesis
See in Reactome
R-HSA-9013695
R-HSA-9013695
Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-6782135
R-HSA-6782210
R-HSA-6782210
Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER
See in Reactome
R-HSA-8941856
R-HSA-8941856
Reactome Name: RUNX3 regulates NOTCH signaling
See in Reactome
R-HSA-8941858
R-HSA-8941858
Reactome Name: Regulation of RUNX3 expression and activity
See in Reactome
R-HSA-6804114
R-HSA-6804114
Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
See in Reactome
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-918233
R-HSA-918233
Reactome Name: TRAF3-dependent IRF activation pathway
See in Reactome
R-HSA-6781827
R-HSA-6781827
Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
See in Reactome
R-HSA-156711
R-HSA-156711
Reactome Name: Polo-like kinase mediated events
See in Reactome
R-HSA-5250924
R-HSA-5250924
Reactome Name: B-WICH complex positively regulates rRNA expression
See in Reactome
R-HSA-6781823
R-HSA-6781823
Reactome Name: Formation of TC-NER Pre-Incision Complex
See in Reactome
R-HSA-9013508
R-HSA-9013508
Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-3214847
R-HSA-3371568
R-HSA-8866907
R-HSA-8866907
Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors
See in Reactome
R-HSA-9614657
R-HSA-9614657
Reactome Name: FOXO-mediated transcription of cell death genes
See in Reactome
R-HSA-9701898
R-HSA-9701898
Reactome Name: STAT3 nuclear events downstream of ALK signaling
See in Reactome
R-HSA-933541
R-HSA-1234158
R-HSA-1234158
Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor
See in Reactome
R-HSA-1368082
R-HSA-1368082
Reactome Name: RORA activates gene expression
See in Reactome
R-HSA-5617472
R-HSA-5617472
Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis
See in Reactome
R-HSA-3899300
R-HSA-3899300
Reactome Name: SUMOylation of transcription cofactors
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8936459
R-HSA-8936459
Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-2197563
R-HSA-2197563
Reactome Name: NOTCH2 intracellular domain regulates transcription
See in Reactome
R-HSA-400253
R-HSA-9707616
R-HSA-3134973
R-HSA-3134973
Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
See in Reactome
R-HSA-201722
R-HSA-201722
Reactome Name: Formation of the beta-catenin:TCF transactivating complex
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8951936
R-HSA-5621575
R-HSA-9031628
R-HSA-6811555
R-HSA-6811555
Reactome Name: PI5P Regulates TP53 Acetylation
See in Reactome
R-HSA-6804758
R-HSA-6804758
Reactome Name: Regulation of TP53 Activity through Acetylation
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-9012852
R-HSA-5633007
R-HSA-168256
R-HSA-9013694
R-HSA-168928
R-HSA-168928
Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta
See in Reactome
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-6791312
R-HSA-6791312
Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-1430728
R-HSA-8864260
R-HSA-8864260
Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-2262752
R-HSA-73894
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-2990846
R-HSA-556833
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-8953897
R-HSA-212165
R-HSA-212165
Reactome Name: Epigenetic regulation of gene expression
See in Reactome
R-HSA-5696398
R-HSA-168249
R-HSA-453274
R-HSA-392499
R-HSA-1234174
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-1980143
R-HSA-8939211
R-HSA-1834949
R-HSA-1834949
Reactome Name: Cytosolic sensors of pathogen-associated DNA
See in Reactome
R-HSA-186712
R-HSA-186712
Reactome Name: Regulation of beta-cell development
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-157118
R-HSA-187037
R-HSA-3247509
R-HSA-195721
R-HSA-1980145
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9614085
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-5688426
R-HSA-201556
R-HSA-5250913
R-HSA-5250913
Reactome Name: Positive epigenetic regulation of rRNA expression
See in Reactome
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-4839726
R-HSA-69275
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-162582
R-HSA-5619507
R-HSA-5619507
Reactome Name: Activation of HOX genes during differentiation
See in Reactome
|
Circadian Clock
Immune System
Cell Cycle
Developmental Biology
Metabolism
Gene expression (Transcription)
DNA Repair
Cellular responses to stimuli
Metabolism of proteins
Chromatin organization
Signal Transduction
|
R-HSA-6782069
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782069
Reaction Name: UVSSA:USP7 deubiquitinates ERCC6
See in Reactome
R-HSA-9760081
()
R-HSA-9760081
Reaction Name: CREBBP, EP300 acetylates NFE2L2
See in Reactome
R-HSA-9011981
(
R-HSA-9018519
)
R-HSA-9011981
Reaction Name: EP300 is recruited to MYC and BCL2 genes
See in Reactome
R-HSA-8878050
(
R-HSA-8939243
)
R-HSA-8878050
Reaction Name: HIPK2 phosphorylates RUNX1 and EP300
See in Reactome
R-HSA-9761836
()
R-HSA-9761836
Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300
See in Reactome
R-HSA-560491
(
R-HSA-381340
)
R-HSA-4396371
(
R-HSA-2122947
)
R-HSA-4396371
Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter
See in Reactome
R-HSA-9038052
(
R-HSA-9018519
)
R-HSA-9038052
Reaction Name: GREB1 binds ESR1:ESTG and co-activators
See in Reactome
R-HSA-8952101
(
R-HSA-8951936
)
R-HSA-8952101
Reaction Name: p14-ARF transcription is stimulated by RUNX proteins
See in Reactome
R-HSA-1234167
(
R-HSA-1234158
)
R-HSA-1234167
Reaction Name: Formation of HIF:CBP:p300 complex at promoters
See in Reactome
R-HSA-9617758
(
R-HSA-9617629
)
R-HSA-9038163
(
R-HSA-9018519
)
R-HSA-9038163
Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
See in Reactome
R-HSA-9016751
(
R-HSA-9013508
)
R-HSA-9016751
Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3
See in Reactome
R-HSA-6782211
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782211
Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site
See in Reactome
R-HSA-560498
(
R-HSA-381340
)
R-HSA-560498
Reaction Name: Expression of Lipoprotein lipase (LPL)
See in Reactome
R-HSA-1980065
(
R-HSA-2122947
)
R-HSA-1980065
Reaction Name: NOTCH1 stimulates HEY transcription
See in Reactome
R-HSA-9759332
()
R-HSA-9759332
Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter
See in Reactome
R-HSA-9613451
(
R-HSA-9031628
)
R-HSA-9613451
Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
See in Reactome
R-HSA-8936621
(
R-HSA-8936459
)
R-HSA-8936621
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
See in Reactome
R-HSA-5628871
(
R-HSA-6804758
)
R-HSA-5628871
Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53
See in Reactome
R-HSA-1980067
(
R-HSA-2122947
)
R-HSA-1980067
Reaction Name: NOTCH1 stimulates MYC transcription
See in Reactome
R-HSA-9620723
(
R-HSA-9031628
)
R-HSA-5250938
(
R-HSA-5250924
)
R-HSA-5250938
Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
See in Reactome
R-HSA-6782204
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782204
Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
See in Reactome
R-HSA-5617867
(
R-HSA-5617472
)
R-HSA-9761849
()
R-HSA-9761849
Reaction Name: AcK-NFE2L2-dependent P6GD gene expression
See in Reactome
R-HSA-9023884
(
R-HSA-9018519
)
R-HSA-9023884
Reaction Name: NCOA1 recruits EP300 to TGFA promoter
See in Reactome
R-HSA-8937050
(
R-HSA-8936459
)
R-HSA-8937050
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
See in Reactome
R-HSA-8952081
(
R-HSA-8951936
)
R-HSA-8952081
Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
See in Reactome
R-HSA-3662335
(
R-HSA-3214847
)
R-HSA-3662335
Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4
See in Reactome
R-HSA-1183003
(
R-HSA-381340
)
R-HSA-6804379
(
R-HSA-6804760
)
R-HSA-4088162
(
R-HSA-156711
)
R-HSA-3134883
(
R-HSA-3134973
)
R-HSA-3134883
Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300
See in Reactome
R-HSA-381309
(
R-HSA-381340
)
R-HSA-381309
Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands
See in Reactome
R-HSA-9023846
(
R-HSA-9018519
)
R-HSA-9023846
Reaction Name: Estrogen-responsive CTSD expression
See in Reactome
R-HSA-1028820
(
R-HSA-933541
)
R-HSA-1028820
Reaction Name: Formation of VAF (virus-activated factor) complex
See in Reactome
R-HSA-8878243
(
R-HSA-8941856
)
R-HSA-8878243
Reaction Name: HES1 gene transcription is inhibited by RUNX3
See in Reactome
R-HSA-9021450
(
R-HSA-9013508
)
R-HSA-9021450
Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes
See in Reactome
R-HSA-9761828
()
R-HSA-1028817
(
R-HSA-918233
)
R-HSA-1028817
Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3
See in Reactome
R-HSA-9008315
(
R-HSA-9018519
)
R-HSA-9008315
Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen
See in Reactome
R-HSA-8936628
(
R-HSA-8936459
)
R-HSA-8936628
Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9023860
(
R-HSA-9018519
)
R-HSA-9023860
Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene
See in Reactome
R-HSA-9761846
()
R-HSA-9761846
Reaction Name: NFE2L2-dependent PGD gene expression
See in Reactome
R-HSA-8936481
(
R-HSA-8936459
)
R-HSA-8936481
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
See in Reactome
R-HSA-5663264
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-6805650
(
R-HSA-6804758
)
R-HSA-6805650
Reaction Name: MTA2-NuRD complex deacetylates TP53
See in Reactome
R-HSA-5617452
(
R-HSA-5617472
)
R-HSA-5617452
Reaction Name: Retinoic acid activates HOXB1 chromatin
See in Reactome
R-HSA-4396347
(
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-4396347
Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter
See in Reactome
R-HSA-9759141
()
R-HSA-9759141
Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene
See in Reactome
R-HSA-9760125
()
R-HSA-9760125
Reaction Name: AcK-NFE2L2-dependent GCLM gene expression
See in Reactome
R-HSA-9613460
(
R-HSA-9031628
)
R-HSA-9620717
(
R-HSA-9031628
)
R-HSA-9620717
Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter
See in Reactome
R-HSA-8951951
(
R-HSA-8951936
)
R-HSA-9029561
(
R-HSA-9029569
)
R-HSA-9029561
Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter
See in Reactome
R-HSA-560473
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-9622604
(
R-HSA-9614657
)
R-HSA-9622604
Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y
See in Reactome
R-HSA-9617064
(
R-HSA-9616222
)
R-HSA-9617064
Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
See in Reactome
R-HSA-9008285
(
R-HSA-9018519
)
R-HSA-9008285
Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
See in Reactome
R-HSA-3371554
(
R-HSA-3371568
)
R-HSA-9701531
(
R-HSA-9701898
)
R-HSA-9701531
Reaction Name: p-Y705,S727 STAT3 is acetylated
See in Reactome
R-HSA-9017835
(
R-HSA-1912408
)
R-HSA-9017835
Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene
See in Reactome
R-HSA-8937097
(
R-HSA-8936459
)
R-HSA-8937097
Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-8936616
(
R-HSA-8936459
)
R-HSA-8936616
Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene
See in Reactome
R-HSA-5663246
(
R-HSA-400253
)
R-HSA-6804229
(
R-HSA-6804760
)
R-HSA-1801587
(
R-HSA-1368082;
R-HSA-1989781;
R-HSA-400253
)
R-HSA-8878056
(
R-HSA-8939243
)
R-HSA-9761812
()
R-HSA-9761812
Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
See in Reactome
R-HSA-4396382
(
R-HSA-2122947
)
R-HSA-4396382
Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes
See in Reactome
R-HSA-5617454
(
R-HSA-5617472
)
R-HSA-560510
(
R-HSA-381340
)
R-HSA-9760097
()
R-HSA-9760097
Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene
See in Reactome
R-HSA-6782004
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782004
Reaction Name: Assembly of the pre-incision complex in TC-NER
See in Reactome
R-HSA-5250930
(
R-HSA-5250924
)
R-HSA-5250930
Reaction Name: B-WICH recruits histone acetyltransferases
See in Reactome
R-HSA-8937016
(
R-HSA-8936459
)
R-HSA-8937016
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
See in Reactome
R-HSA-400342
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-6782138
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782138
Reaction Name: ERCC5 and RPA bind TC-NER site
See in Reactome
R-HSA-5617859
(
R-HSA-5617472
)
R-HSA-5617859
Reaction Name: Retinoic acid activates HOXB4 chromatin
See in Reactome
R-HSA-8952058
(
R-HSA-8951936
)
R-HSA-8952058
Reaction Name: CCND1 binds RUNX3 and displaces EP300
See in Reactome
R-HSA-1980047
(
R-HSA-210744;
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-1980047
Reaction Name: NOTCH1 stimulates HES1 transcription
See in Reactome
R-HSA-1235037
(
R-HSA-1234158
)
R-HSA-8878237
(
R-HSA-8941856
)
R-HSA-8878237
Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter
See in Reactome
R-HSA-9622579
(
R-HSA-9614657
)
R-HSA-9622579
Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter
See in Reactome
R-HSA-9620515
(
R-HSA-9617629
)
R-HSA-9620515
Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress
See in Reactome
R-HSA-933536
(
R-HSA-933541
)
R-HSA-933536
Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300
See in Reactome
R-HSA-9760128
()
R-HSA-9760128
Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression
See in Reactome
R-HSA-9617683
(
R-HSA-9617629
)
R-HSA-9617683
Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4
See in Reactome
R-HSA-1912415
(
R-HSA-1912408
)
R-HSA-1028812
(
R-HSA-918233
)
R-HSA-5693644
(
R-HSA-5617472
)
R-HSA-5693644
Reaction Name: HOXB1 maintains activation of HOXB1 chromatin
See in Reactome
R-HSA-9760082
()
R-HSA-1912394
(
R-HSA-2122947
)
R-HSA-1912394
Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML
See in Reactome
R-HSA-560493
(
R-HSA-381340
)
R-HSA-5617862
(
R-HSA-5617472
)
R-HSA-5617862
Reaction Name: Retinoic acid activates HOXA4 chromatin
See in Reactome
R-HSA-560517
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-560517
Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT)
See in Reactome
R-HSA-1912393
(
R-HSA-2122947
)
R-HSA-1912393
Reaction Name: MAML in complex with NICD1 recruits CDK8
See in Reactome
R-HSA-8935731
(
R-HSA-8936459
)
R-HSA-8935731
Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-6782208
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782208
Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
See in Reactome
R-HSA-5663293
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-1028819
(
R-HSA-933541
)
R-HSA-1028819
Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes
See in Reactome
R-HSA-5660666
(
R-HSA-5621575
)
R-HSA-5660666
Reaction Name: CBP and p300 binds NF-kB complex
See in Reactome
R-HSA-1912416
(
R-HSA-1912408
)
R-HSA-1912391
(
R-HSA-2122947
)
R-HSA-1912391
Reaction Name: NICD1 is phosphorylated by CDK8
See in Reactome
R-HSA-9761815
()
R-HSA-9761815
Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene
See in Reactome
R-HSA-549475
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-9760122
()
R-HSA-9760122
Reaction Name: AcK-NFE2L2-dependent GCLC gene expression
See in Reactome
R-HSA-6782227
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782227
Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER
See in Reactome
R-HSA-6811508
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-6811508
Reaction Name: ING2-bound EP300 acetylates TP53
See in Reactome
R-HSA-1235035
(
R-HSA-1234158
)
R-HSA-1235035
Reaction Name: Expression of Carbonic Anhydrase IX (CA9)
See in Reactome
R-HSA-9021451
(
R-HSA-9013508
)
R-HSA-9021451
Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter
See in Reactome
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9023840
(
R-HSA-9018519
)
R-HSA-9023840
Reaction Name: HATs and coactivators are recruited to the CTSD gene
See in Reactome
R-HSA-6811479
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-5617877
(
R-HSA-5617472
)
R-HSA-8864307
(
R-HSA-8866907
)
R-HSA-8864307
Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
See in Reactome
R-HSA-1028815
(
R-HSA-918233
)
R-HSA-1028815
Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta
See in Reactome
R-HSA-6804383
(
R-HSA-6804760
)
R-HSA-6782234
(
R-HSA-6781827
)
R-HSA-6782234
Reaction Name: Recovery of RNA synthesis after TC-NER
See in Reactome
R-HSA-9011975
(
R-HSA-9018519
)
R-HSA-9011975
Reaction Name: Estrogen-responsive MYC gene expression
See in Reactome
R-HSA-8878220
(
R-HSA-8941856
)
R-HSA-8878220
Reaction Name: RUNX3 binds the NOTCH1 coactivator complex
See in Reactome
R-HSA-2976551
(
R-HSA-2197563
)
R-HSA-2976551
Reaction Name: NOTCH2 stimulates GZMB transcription
See in Reactome
R-HSA-1368081
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-5617431
(
R-HSA-5617472
)
R-HSA-5617431
Reaction Name: Retinoic acid activates HOXA1 chromatin
See in Reactome
R-HSA-1980078
(
R-HSA-2122947
)
R-HSA-1980078
Reaction Name: NOTCH1 stimulates HES5 transcription
See in Reactome
R-HSA-4396379
(
R-HSA-2122947
)
R-HSA-4396379
Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter
See in Reactome
R-HSA-3215152
(
R-HSA-6804114
)
R-HSA-3215152
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
See in Reactome
R-HSA-4088152
(
R-HSA-156711
)
R-HSA-4088152
Reaction Name: FOXM1 stimulates CDC25A transcription
See in Reactome
R-HSA-9009371
(
R-HSA-9018519
)
R-HSA-9009371
Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter
See in Reactome
R-HSA-9023859
(
R-HSA-9018519
)
R-HSA-9023859
Reaction Name: Estrogen-responsive TFF1 gene expression
See in Reactome
R-HSA-1368087
(
R-HSA-400253
)
R-HSA-1368087
Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene
See in Reactome
R-HSA-1368065
(
R-HSA-1989781;
R-HSA-400253;
R-HSA-9707616
)
R-HSA-1183058
(
R-HSA-381340
)
R-HSA-9622572
(
R-HSA-9614657
)
R-HSA-9622572
Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
See in Reactome
R-HSA-3899291
(
R-HSA-3899300
)
R-HSA-3899291
Reaction Name: SUMOylation of EP300 with SUMO1
See in Reactome
R-HSA-9634433
(
R-HSA-9616222
)
R-HSA-9634433
Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid
See in Reactome
R-HSA-9605057
(
R-HSA-9029569
)
R-HSA-9605057
Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3
See in Reactome
R-HSA-5617471
(
R-HSA-5617472
)
R-HSA-9761841
()
R-HSA-9761841
Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression
See in Reactome
R-HSA-5691381
(
R-HSA-5689901
)
R-HSA-5691381
Reaction Name: MYSM1 deubiquitinates Histone H2A
See in Reactome
R-HSA-5617874
(
R-HSA-5617472
)
R-HSA-9760099
()
R-HSA-9760099
Reaction Name: AcK-NFE2L2 binds the GCLC gene
See in Reactome
R-HSA-9018499
(
R-HSA-9018519
)
R-HSA-9018499
Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter
See in Reactome
R-HSA-9760103
()
R-HSA-9760103
Reaction Name: AcK-NFE2L2 binds the GCLM gene
See in Reactome
R-HSA-560472
(
R-HSA-381340
)
R-HSA-560472
Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
See in Reactome
R-HSA-6782131
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782131
Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-8935740
(
R-HSA-8936459
)
R-HSA-8935740
Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene
See in Reactome
R-HSA-9009378
(
R-HSA-9018519
)
R-HSA-9009378
Reaction Name: Estrogen-responsive CCND1 gene expression
See in Reactome
R-HSA-8952419
(
R-HSA-8941858
)
R-HSA-6782224
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782224
Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER
See in Reactome
R-HSA-8936979
(
R-HSA-8936459
)
R-HSA-8936979
Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene
See in Reactome
R-HSA-1235070
(
R-HSA-1234158
)
R-HSA-1235070
Reaction Name: Expression of Erythropoietin (EPO)
See in Reactome
R-HSA-5660660
(
R-HSA-5621575
)
R-HSA-3215144
(
R-HSA-6804114
)
R-HSA-3215144
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription
See in Reactome
R-HSA-8951966
(
R-HSA-8951936
)
R-HSA-9008271
(
R-HSA-9018519
)
R-HSA-9008271
Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
See in Reactome
R-HSA-9011941
(
R-HSA-9018519
)
R-HSA-9011941
Reaction Name: Estrogen-responsive BCL2 gene expression
See in Reactome
R-HSA-2976563
(
R-HSA-2197563
)
R-HSA-2976563
Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
See in Reactome
R-HSA-5663273
(
R-HSA-400253
)
R-HSA-5663273
Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene
See in Reactome
R-HSA-9604499
(
R-HSA-933541
)
R-HSA-9604499
Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300
See in Reactome
R-HSA-9604664
(
R-HSA-9013695
)
R-HSA-9604664
Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
See in Reactome
R-HSA-6782141
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782141
Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
See in Reactome
R-HSA-5617896
(
R-HSA-5617472
)
R-HSA-5617896
Reaction Name: Retinoic acid activates HOXD4 chromatin
See in Reactome
R-HSA-8937037
(
R-HSA-8936459
)
R-HSA-8937037
Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene
See in Reactome
R-HSA-9759364
()
R-HSA-9759364
Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression
See in Reactome
R-HSA-9617735
(
R-HSA-9617629
)
R-HSA-9617735
Reaction Name: TXN disrupts FOXO4 complex with EP300
See in Reactome
R-HSA-3322427
(
R-HSA-201722
)
R-HSA-3322427
Reaction Name: Beta-catenin recruits CBP/p300
See in Reactome
R-HSA-9018497
(
R-HSA-9018519
)
R-HSA-9018497
Reaction Name: Estrogen-responsive TFF3 gene expression
See in Reactome
R-HSA-8936995
(
R-HSA-8936459
)
R-HSA-8936995
Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9684118
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-9684118
Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-6804242
(
R-HSA-6804760
)
R-HSA-6804242
Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5
See in Reactome
R-HSA-9759186
()
R-HSA-9759186
Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression
See in Reactome
R-HSA-3222093
(
R-HSA-6804758
)
|
MONDO:0021230 |
EP300 |
Q09472 |
2.3.1.-
2.3.1.48
|
R-HSA-9617629
R-HSA-9617629
Reactome Name: Regulation of FOXO transcriptional activity by acetylation
See in Reactome
R-HSA-210744
R-HSA-210744
Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
See in Reactome
R-HSA-5689901
R-HSA-6804760
R-HSA-6804760
Reactome Name: Regulation of TP53 Activity through Methylation
See in Reactome
R-HSA-8939243
R-HSA-8939243
Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
See in Reactome
R-HSA-381340
R-HSA-381340
Reactome Name: Transcriptional regulation of white adipocyte differentiation
See in Reactome
R-HSA-9616222
R-HSA-9616222
Reactome Name: Transcriptional regulation of granulopoiesis
See in Reactome
R-HSA-9013695
R-HSA-9013695
Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-6782135
R-HSA-6782210
R-HSA-6782210
Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER
See in Reactome
R-HSA-8941856
R-HSA-8941856
Reactome Name: RUNX3 regulates NOTCH signaling
See in Reactome
R-HSA-8941858
R-HSA-8941858
Reactome Name: Regulation of RUNX3 expression and activity
See in Reactome
R-HSA-6804114
R-HSA-6804114
Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
See in Reactome
R-HSA-1989781
R-HSA-1989781
Reactome Name: PPARA activates gene expression
See in Reactome
R-HSA-9018519
R-HSA-9018519
Reactome Name: Estrogen-dependent gene expression
See in Reactome
R-HSA-918233
R-HSA-918233
Reactome Name: TRAF3-dependent IRF activation pathway
See in Reactome
R-HSA-6781827
R-HSA-6781827
Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
See in Reactome
R-HSA-156711
R-HSA-156711
Reactome Name: Polo-like kinase mediated events
See in Reactome
R-HSA-5250924
R-HSA-5250924
Reactome Name: B-WICH complex positively regulates rRNA expression
See in Reactome
R-HSA-6781823
R-HSA-6781823
Reactome Name: Formation of TC-NER Pre-Incision Complex
See in Reactome
R-HSA-9013508
R-HSA-9013508
Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-3214847
R-HSA-3371568
R-HSA-8866907
R-HSA-8866907
Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors
See in Reactome
R-HSA-9614657
R-HSA-9614657
Reactome Name: FOXO-mediated transcription of cell death genes
See in Reactome
R-HSA-9701898
R-HSA-9701898
Reactome Name: STAT3 nuclear events downstream of ALK signaling
See in Reactome
R-HSA-933541
R-HSA-1234158
R-HSA-1234158
Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor
See in Reactome
R-HSA-1368082
R-HSA-1368082
Reactome Name: RORA activates gene expression
See in Reactome
R-HSA-5617472
R-HSA-5617472
Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis
See in Reactome
R-HSA-3899300
R-HSA-3899300
Reactome Name: SUMOylation of transcription cofactors
See in Reactome
R-HSA-9029569
R-HSA-9029569
Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
See in Reactome
R-HSA-8936459
R-HSA-8936459
Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
See in Reactome
R-HSA-2122947
R-HSA-2122947
Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription
See in Reactome
R-HSA-2197563
R-HSA-2197563
Reactome Name: NOTCH2 intracellular domain regulates transcription
See in Reactome
R-HSA-400253
R-HSA-9707616
R-HSA-3134973
R-HSA-3134973
Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
See in Reactome
R-HSA-201722
R-HSA-201722
Reactome Name: Formation of the beta-catenin:TCF transactivating complex
See in Reactome
R-HSA-1912408
R-HSA-1912408
Reactome Name: Pre-NOTCH Transcription and Translation
See in Reactome
R-HSA-8951936
R-HSA-5621575
R-HSA-9031628
R-HSA-6811555
R-HSA-6811555
Reactome Name: PI5P Regulates TP53 Acetylation
See in Reactome
R-HSA-6804758
R-HSA-6804758
Reactome Name: Regulation of TP53 Activity through Acetylation
See in Reactome
|
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-9012852
R-HSA-5633007
R-HSA-168256
R-HSA-9013694
R-HSA-168928
R-HSA-168928
Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta
See in Reactome
R-HSA-1640170
R-HSA-597592
R-HSA-597592
Reactome Name: Post-translational protein modification
See in Reactome
R-HSA-6791312
R-HSA-6791312
Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes
See in Reactome
R-HSA-1266738
R-HSA-73857
R-HSA-1430728
R-HSA-8864260
R-HSA-8864260
Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
See in Reactome
R-HSA-166520
R-HSA-212436
R-HSA-74160
R-HSA-400206
R-HSA-400206
Reactome Name: Regulation of lipid metabolism by PPARalpha
See in Reactome
R-HSA-2262752
R-HSA-73894
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-2990846
R-HSA-556833
R-HSA-9024446
R-HSA-9024446
Reactome Name: NR1H2 and NR1H3-mediated signaling
See in Reactome
R-HSA-8878159
R-HSA-8878159
Reactome Name: Transcriptional regulation by RUNX3
See in Reactome
R-HSA-5621481
R-HSA-5621481
Reactome Name: C-type lectin receptors (CLRs)
See in Reactome
R-HSA-8953897
R-HSA-212165
R-HSA-212165
Reactome Name: Epigenetic regulation of gene expression
See in Reactome
R-HSA-5696398
R-HSA-168249
R-HSA-453274
R-HSA-392499
R-HSA-1234174
R-HSA-3371571
R-HSA-3371571
Reactome Name: HSF1-dependent transactivation
See in Reactome
R-HSA-1980143
R-HSA-8939211
R-HSA-1834949
R-HSA-1834949
Reactome Name: Cytosolic sensors of pathogen-associated DNA
See in Reactome
R-HSA-186712
R-HSA-186712
Reactome Name: Regulation of beta-cell development
See in Reactome
R-HSA-8878171
R-HSA-8878171
Reactome Name: Transcriptional regulation by RUNX1
See in Reactome
R-HSA-1912422
R-HSA-1912422
Reactome Name: Pre-NOTCH Expression and Processing
See in Reactome
R-HSA-157118
R-HSA-187037
R-HSA-3247509
R-HSA-195721
R-HSA-1980145
R-HSA-9006931
R-HSA-9006931
Reactome Name: Signaling by Nuclear Receptors
See in Reactome
R-HSA-9614085
R-HSA-3108232
R-HSA-3108232
Reactome Name: SUMO E3 ligases SUMOylate target proteins
See in Reactome
R-HSA-5688426
R-HSA-201556
R-HSA-5250913
R-HSA-5250913
Reactome Name: Positive epigenetic regulation of rRNA expression
See in Reactome
R-HSA-3371556
R-HSA-3371556
Reactome Name: Cellular response to heat stress
See in Reactome
R-HSA-4839726
R-HSA-69275
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-162582
R-HSA-5619507
R-HSA-5619507
Reactome Name: Activation of HOX genes during differentiation
See in Reactome
|
Circadian Clock
Immune System
Cell Cycle
Developmental Biology
Metabolism
Gene expression (Transcription)
DNA Repair
Cellular responses to stimuli
Metabolism of proteins
Chromatin organization
Signal Transduction
|
R-HSA-6782069
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782069
Reaction Name: UVSSA:USP7 deubiquitinates ERCC6
See in Reactome
R-HSA-9760081
()
R-HSA-9760081
Reaction Name: CREBBP, EP300 acetylates NFE2L2
See in Reactome
R-HSA-9011981
(
R-HSA-9018519
)
R-HSA-9011981
Reaction Name: EP300 is recruited to MYC and BCL2 genes
See in Reactome
R-HSA-8878050
(
R-HSA-8939243
)
R-HSA-8878050
Reaction Name: HIPK2 phosphorylates RUNX1 and EP300
See in Reactome
R-HSA-9761836
()
R-HSA-9761836
Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300
See in Reactome
R-HSA-560491
(
R-HSA-381340
)
R-HSA-4396371
(
R-HSA-2122947
)
R-HSA-4396371
Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter
See in Reactome
R-HSA-9038052
(
R-HSA-9018519
)
R-HSA-9038052
Reaction Name: GREB1 binds ESR1:ESTG and co-activators
See in Reactome
R-HSA-8952101
(
R-HSA-8951936
)
R-HSA-8952101
Reaction Name: p14-ARF transcription is stimulated by RUNX proteins
See in Reactome
R-HSA-1234167
(
R-HSA-1234158
)
R-HSA-1234167
Reaction Name: Formation of HIF:CBP:p300 complex at promoters
See in Reactome
R-HSA-9617758
(
R-HSA-9617629
)
R-HSA-9038163
(
R-HSA-9018519
)
R-HSA-9038163
Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators
See in Reactome
R-HSA-9016751
(
R-HSA-9013508
)
R-HSA-9016751
Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3
See in Reactome
R-HSA-6782211
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782211
Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site
See in Reactome
R-HSA-560498
(
R-HSA-381340
)
R-HSA-560498
Reaction Name: Expression of Lipoprotein lipase (LPL)
See in Reactome
R-HSA-1980065
(
R-HSA-2122947
)
R-HSA-1980065
Reaction Name: NOTCH1 stimulates HEY transcription
See in Reactome
R-HSA-9759332
()
R-HSA-9759332
Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter
See in Reactome
R-HSA-9613451
(
R-HSA-9031628
)
R-HSA-9613451
Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes
See in Reactome
R-HSA-8936621
(
R-HSA-8936459
)
R-HSA-8936621
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter
See in Reactome
R-HSA-5628871
(
R-HSA-6804758
)
R-HSA-5628871
Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53
See in Reactome
R-HSA-1980067
(
R-HSA-2122947
)
R-HSA-1980067
Reaction Name: NOTCH1 stimulates MYC transcription
See in Reactome
R-HSA-9620723
(
R-HSA-9031628
)
R-HSA-5250938
(
R-HSA-5250924
)
R-HSA-5250938
Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9
See in Reactome
R-HSA-6782204
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782204
Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER
See in Reactome
R-HSA-5617867
(
R-HSA-5617472
)
R-HSA-9761849
()
R-HSA-9761849
Reaction Name: AcK-NFE2L2-dependent P6GD gene expression
See in Reactome
R-HSA-9023884
(
R-HSA-9018519
)
R-HSA-9023884
Reaction Name: NCOA1 recruits EP300 to TGFA promoter
See in Reactome
R-HSA-8937050
(
R-HSA-8936459
)
R-HSA-8937050
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
See in Reactome
R-HSA-8952081
(
R-HSA-8951936
)
R-HSA-8952081
Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus
See in Reactome
R-HSA-3662335
(
R-HSA-3214847
)
R-HSA-3662335
Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4
See in Reactome
R-HSA-1183003
(
R-HSA-381340
)
R-HSA-6804379
(
R-HSA-6804760
)
R-HSA-4088162
(
R-HSA-156711
)
R-HSA-3134883
(
R-HSA-3134973
)
R-HSA-3134883
Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300
See in Reactome
R-HSA-381309
(
R-HSA-381340
)
R-HSA-381309
Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands
See in Reactome
R-HSA-9023846
(
R-HSA-9018519
)
R-HSA-9023846
Reaction Name: Estrogen-responsive CTSD expression
See in Reactome
R-HSA-1028820
(
R-HSA-933541
)
R-HSA-1028820
Reaction Name: Formation of VAF (virus-activated factor) complex
See in Reactome
R-HSA-8878243
(
R-HSA-8941856
)
R-HSA-8878243
Reaction Name: HES1 gene transcription is inhibited by RUNX3
See in Reactome
R-HSA-9021450
(
R-HSA-9013508
)
R-HSA-9021450
Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes
See in Reactome
R-HSA-9761828
()
R-HSA-1028817
(
R-HSA-918233
)
R-HSA-1028817
Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3
See in Reactome
R-HSA-9008315
(
R-HSA-9018519
)
R-HSA-9008315
Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen
See in Reactome
R-HSA-8936628
(
R-HSA-8936459
)
R-HSA-8936628
Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9023860
(
R-HSA-9018519
)
R-HSA-9023860
Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene
See in Reactome
R-HSA-9761846
()
R-HSA-9761846
Reaction Name: NFE2L2-dependent PGD gene expression
See in Reactome
R-HSA-8936481
(
R-HSA-8936459
)
R-HSA-8936481
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter
See in Reactome
R-HSA-5663264
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-6805650
(
R-HSA-6804758
)
R-HSA-6805650
Reaction Name: MTA2-NuRD complex deacetylates TP53
See in Reactome
R-HSA-5617452
(
R-HSA-5617472
)
R-HSA-5617452
Reaction Name: Retinoic acid activates HOXB1 chromatin
See in Reactome
R-HSA-4396347
(
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-4396347
Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter
See in Reactome
R-HSA-9759141
()
R-HSA-9759141
Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene
See in Reactome
R-HSA-9760125
()
R-HSA-9760125
Reaction Name: AcK-NFE2L2-dependent GCLM gene expression
See in Reactome
R-HSA-9613460
(
R-HSA-9031628
)
R-HSA-9620717
(
R-HSA-9031628
)
R-HSA-9620717
Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter
See in Reactome
R-HSA-8951951
(
R-HSA-8951936
)
R-HSA-9029561
(
R-HSA-9029569
)
R-HSA-9029561
Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter
See in Reactome
R-HSA-560473
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-9622604
(
R-HSA-9614657
)
R-HSA-9622604
Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y
See in Reactome
R-HSA-9617064
(
R-HSA-9616222
)
R-HSA-9617064
Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene
See in Reactome
R-HSA-9008285
(
R-HSA-9018519
)
R-HSA-9008285
Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3
See in Reactome
R-HSA-3371554
(
R-HSA-3371568
)
R-HSA-9701531
(
R-HSA-9701898
)
R-HSA-9701531
Reaction Name: p-Y705,S727 STAT3 is acetylated
See in Reactome
R-HSA-9017835
(
R-HSA-1912408
)
R-HSA-9017835
Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene
See in Reactome
R-HSA-8937097
(
R-HSA-8936459
)
R-HSA-8937097
Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-8936616
(
R-HSA-8936459
)
R-HSA-8936616
Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene
See in Reactome
R-HSA-5663246
(
R-HSA-400253
)
R-HSA-6804229
(
R-HSA-6804760
)
R-HSA-1801587
(
R-HSA-1368082;
R-HSA-1989781;
R-HSA-400253
)
R-HSA-8878056
(
R-HSA-8939243
)
R-HSA-9761812
()
R-HSA-9761812
Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD
See in Reactome
R-HSA-4396382
(
R-HSA-2122947
)
R-HSA-4396382
Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes
See in Reactome
R-HSA-5617454
(
R-HSA-5617472
)
R-HSA-560510
(
R-HSA-381340
)
R-HSA-9760097
()
R-HSA-9760097
Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene
See in Reactome
R-HSA-6782004
(
R-HSA-6781823;
R-HSA-6781827
)
R-HSA-6782004
Reaction Name: Assembly of the pre-incision complex in TC-NER
See in Reactome
R-HSA-5250930
(
R-HSA-5250924
)
R-HSA-5250930
Reaction Name: B-WICH recruits histone acetyltransferases
See in Reactome
R-HSA-8937016
(
R-HSA-8936459
)
R-HSA-8937016
Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter
See in Reactome
R-HSA-400342
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-6782138
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782138
Reaction Name: ERCC5 and RPA bind TC-NER site
See in Reactome
R-HSA-5617859
(
R-HSA-5617472
)
R-HSA-5617859
Reaction Name: Retinoic acid activates HOXB4 chromatin
See in Reactome
R-HSA-8952058
(
R-HSA-8951936
)
R-HSA-8952058
Reaction Name: CCND1 binds RUNX3 and displaces EP300
See in Reactome
R-HSA-1980047
(
R-HSA-210744;
R-HSA-2122947;
R-HSA-8941856
)
R-HSA-1980047
Reaction Name: NOTCH1 stimulates HES1 transcription
See in Reactome
R-HSA-1235037
(
R-HSA-1234158
)
R-HSA-8878237
(
R-HSA-8941856
)
R-HSA-8878237
Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter
See in Reactome
R-HSA-9622579
(
R-HSA-9614657
)
R-HSA-9622579
Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter
See in Reactome
R-HSA-9620515
(
R-HSA-9617629
)
R-HSA-9620515
Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress
See in Reactome
R-HSA-933536
(
R-HSA-933541
)
R-HSA-933536
Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300
See in Reactome
R-HSA-9760128
()
R-HSA-9760128
Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression
See in Reactome
R-HSA-9617683
(
R-HSA-9617629
)
R-HSA-9617683
Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4
See in Reactome
R-HSA-1912415
(
R-HSA-1912408
)
R-HSA-1028812
(
R-HSA-918233
)
R-HSA-5693644
(
R-HSA-5617472
)
R-HSA-5693644
Reaction Name: HOXB1 maintains activation of HOXB1 chromatin
See in Reactome
R-HSA-9760082
()
R-HSA-1912394
(
R-HSA-2122947
)
R-HSA-1912394
Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML
See in Reactome
R-HSA-560493
(
R-HSA-381340
)
R-HSA-5617862
(
R-HSA-5617472
)
R-HSA-5617862
Reaction Name: Retinoic acid activates HOXA4 chromatin
See in Reactome
R-HSA-560517
(
R-HSA-1989781;
R-HSA-381340
)
R-HSA-560517
Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT)
See in Reactome
R-HSA-1912393
(
R-HSA-2122947
)
R-HSA-1912393
Reaction Name: MAML in complex with NICD1 recruits CDK8
See in Reactome
R-HSA-8935731
(
R-HSA-8936459
)
R-HSA-8935731
Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-6782208
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782208
Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER
See in Reactome
R-HSA-5663293
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-1028819
(
R-HSA-933541
)
R-HSA-1028819
Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes
See in Reactome
R-HSA-5660666
(
R-HSA-5621575
)
R-HSA-5660666
Reaction Name: CBP and p300 binds NF-kB complex
See in Reactome
R-HSA-1912416
(
R-HSA-1912408
)
R-HSA-1912391
(
R-HSA-2122947
)
R-HSA-1912391
Reaction Name: NICD1 is phosphorylated by CDK8
See in Reactome
R-HSA-9761815
()
R-HSA-9761815
Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene
See in Reactome
R-HSA-549475
(
R-HSA-400253;
R-HSA-9707616
)
R-HSA-9760122
()
R-HSA-9760122
Reaction Name: AcK-NFE2L2-dependent GCLC gene expression
See in Reactome
R-HSA-6782227
(
R-HSA-6781827;
R-HSA-6782210
)
R-HSA-6782227
Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER
See in Reactome
R-HSA-6811508
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-6811508
Reaction Name: ING2-bound EP300 acetylates TP53
See in Reactome
R-HSA-1235035
(
R-HSA-1234158
)
R-HSA-1235035
Reaction Name: Expression of Carbonic Anhydrase IX (CA9)
See in Reactome
R-HSA-9021451
(
R-HSA-9013508
)
R-HSA-9021451
Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter
See in Reactome
R-HSA-8951977
(
R-HSA-8951936
)
R-HSA-8951977
Reaction Name: Acetylated RUNX3 binds to BRD2
See in Reactome
R-HSA-9023840
(
R-HSA-9018519
)
R-HSA-9023840
Reaction Name: HATs and coactivators are recruited to the CTSD gene
See in Reactome
R-HSA-6811479
(
R-HSA-6804758;
R-HSA-6811555
)
R-HSA-5617877
(
R-HSA-5617472
)
R-HSA-8864307
(
R-HSA-8866907
)
R-HSA-8864307
Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
See in Reactome
R-HSA-1028815
(
R-HSA-918233
)
R-HSA-1028815
Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta
See in Reactome
R-HSA-6804383
(
R-HSA-6804760
)
R-HSA-6782234
(
R-HSA-6781827
)
R-HSA-6782234
Reaction Name: Recovery of RNA synthesis after TC-NER
See in Reactome
R-HSA-9011975
(
R-HSA-9018519
)
R-HSA-9011975
Reaction Name: Estrogen-responsive MYC gene expression
See in Reactome
R-HSA-8878220
(
R-HSA-8941856
)
R-HSA-8878220
Reaction Name: RUNX3 binds the NOTCH1 coactivator complex
See in Reactome
R-HSA-2976551
(
R-HSA-2197563
)
R-HSA-2976551
Reaction Name: NOTCH2 stimulates GZMB transcription
See in Reactome
R-HSA-1368081
(
R-HSA-1368082;
R-HSA-400253
)
R-HSA-5617431
(
R-HSA-5617472
)
R-HSA-5617431
Reaction Name: Retinoic acid activates HOXA1 chromatin
See in Reactome
R-HSA-1980078
(
R-HSA-2122947
)
R-HSA-1980078
Reaction Name: NOTCH1 stimulates HES5 transcription
See in Reactome
R-HSA-4396379
(
R-HSA-2122947
)
R-HSA-4396379
Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter
See in Reactome
R-HSA-3215152
(
R-HSA-6804114
)
R-HSA-3215152
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter
See in Reactome
R-HSA-4088152
(
R-HSA-156711
)
R-HSA-4088152
Reaction Name: FOXM1 stimulates CDC25A transcription
See in Reactome
R-HSA-9009371
(
R-HSA-9018519
)
R-HSA-9009371
Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter
See in Reactome
R-HSA-9023859
(
R-HSA-9018519
)
R-HSA-9023859
Reaction Name: Estrogen-responsive TFF1 gene expression
See in Reactome
R-HSA-1368087
(
R-HSA-400253
)
R-HSA-1368087
Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene
See in Reactome
R-HSA-1368065
(
R-HSA-1989781;
R-HSA-400253;
R-HSA-9707616
)
R-HSA-1183058
(
R-HSA-381340
)
R-HSA-9622572
(
R-HSA-9614657
)
R-HSA-9622572
Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter
See in Reactome
R-HSA-3899291
(
R-HSA-3899300
)
R-HSA-3899291
Reaction Name: SUMOylation of EP300 with SUMO1
See in Reactome
R-HSA-9634433
(
R-HSA-9616222
)
R-HSA-9634433
Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid
See in Reactome
R-HSA-9605057
(
R-HSA-9029569
)
R-HSA-9605057
Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3
See in Reactome
R-HSA-5617471
(
R-HSA-5617472
)
R-HSA-9761841
()
R-HSA-9761841
Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression
See in Reactome
R-HSA-5691381
(
R-HSA-5689901
)
R-HSA-5691381
Reaction Name: MYSM1 deubiquitinates Histone H2A
See in Reactome
R-HSA-5617874
(
R-HSA-5617472
)
R-HSA-9760099
()
R-HSA-9760099
Reaction Name: AcK-NFE2L2 binds the GCLC gene
See in Reactome
R-HSA-9018499
(
R-HSA-9018519
)
R-HSA-9018499
Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter
See in Reactome
R-HSA-9760103
()
R-HSA-9760103
Reaction Name: AcK-NFE2L2 binds the GCLM gene
See in Reactome
R-HSA-560472
(
R-HSA-381340
)
R-HSA-560472
Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C)
See in Reactome
R-HSA-6782131
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782131
Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-8935740
(
R-HSA-8936459
)
R-HSA-8935740
Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene
See in Reactome
R-HSA-9009378
(
R-HSA-9018519
)
R-HSA-9009378
Reaction Name: Estrogen-responsive CCND1 gene expression
See in Reactome
R-HSA-8952419
(
R-HSA-8941858
)
R-HSA-6782224
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782224
Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER
See in Reactome
R-HSA-8936979
(
R-HSA-8936459
)
R-HSA-8936979
Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene
See in Reactome
R-HSA-1235070
(
R-HSA-1234158
)
R-HSA-1235070
Reaction Name: Expression of Erythropoietin (EPO)
See in Reactome
R-HSA-5660660
(
R-HSA-5621575
)
R-HSA-3215144
(
R-HSA-6804114
)
R-HSA-3215144
Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription
See in Reactome
R-HSA-8951966
(
R-HSA-8951936
)
R-HSA-9008271
(
R-HSA-9018519
)
R-HSA-9008271
Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter
See in Reactome
R-HSA-9011941
(
R-HSA-9018519
)
R-HSA-9011941
Reaction Name: Estrogen-responsive BCL2 gene expression
See in Reactome
R-HSA-2976563
(
R-HSA-2197563
)
R-HSA-2976563
Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter
See in Reactome
R-HSA-5663273
(
R-HSA-400253
)
R-HSA-5663273
Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene
See in Reactome
R-HSA-9604499
(
R-HSA-933541
)
R-HSA-9604499
Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300
See in Reactome
R-HSA-9604664
(
R-HSA-9013695
)
R-HSA-9604664
Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4
See in Reactome
R-HSA-6782141
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-6782141
Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER
See in Reactome
R-HSA-5617896
(
R-HSA-5617472
)
R-HSA-5617896
Reaction Name: Retinoic acid activates HOXD4 chromatin
See in Reactome
R-HSA-8937037
(
R-HSA-8936459
)
R-HSA-8937037
Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene
See in Reactome
R-HSA-9759364
()
R-HSA-9759364
Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression
See in Reactome
R-HSA-9617735
(
R-HSA-9617629
)
R-HSA-9617735
Reaction Name: TXN disrupts FOXO4 complex with EP300
See in Reactome
R-HSA-3322427
(
R-HSA-201722
)
R-HSA-3322427
Reaction Name: Beta-catenin recruits CBP/p300
See in Reactome
R-HSA-9018497
(
R-HSA-9018519
)
R-HSA-9018497
Reaction Name: Estrogen-responsive TFF3 gene expression
See in Reactome
R-HSA-8936995
(
R-HSA-8936459
)
R-HSA-8936995
Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
See in Reactome
R-HSA-9684118
(
R-HSA-6781827;
R-HSA-6782135
)
R-HSA-9684118
Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER
See in Reactome
R-HSA-6804242
(
R-HSA-6804760
)
R-HSA-6804242
Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5
See in Reactome
R-HSA-9759186
()
R-HSA-9759186
Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression
See in Reactome
R-HSA-3222093
(
R-HSA-6804758
)
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