MONDO:0005290 |
MONDO:0005290
Disease Name: rhabdomyolysis
All associated enzymes in DAR:
PGAM2
ACADVL
AHCY
ACADVL |
P49748 |
1.3.8.9
|
R-HSA-381038
R-HSA-381038
Reactome Name: XBP1(S) activates chaperone genes
See in Reactome
R-HSA-77305
R-HSA-77305
Reactome Name: Beta oxidation of palmitoyl-CoA to myristoyl-CoA
See in Reactome
|
R-HSA-77289
R-HSA-77289
Reactome Name: Mitochondrial Fatty Acid Beta-Oxidation
See in Reactome
R-HSA-381119
R-HSA-381119
Reactome Name: Unfolded Protein Response (UPR)
See in Reactome
R-HSA-8953897
R-HSA-2262752
R-HSA-77286
R-HSA-77286
Reactome Name: mitochondrial fatty acid beta-oxidation of saturated fatty acids
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-556833
R-HSA-381070
|
Cellular responses to stimuli
Metabolism
|
R-HSA-1791069
(
R-HSA-381038
)
R-HSA-77299
(
R-HSA-77305
)
R-HSA-77299
Reaction Name: palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2
See in Reactome
|
MONDO:0005336 |
MONDO:0005336
Disease Name: myopathy
OMIM id: OMIM:300695
All associated enzymes in DAR:
ACADVL
ACADVL |
P49748 |
1.3.8.9
|
R-HSA-381038
R-HSA-381038
Reactome Name: XBP1(S) activates chaperone genes
See in Reactome
R-HSA-77305
R-HSA-77305
Reactome Name: Beta oxidation of palmitoyl-CoA to myristoyl-CoA
See in Reactome
|
R-HSA-77289
R-HSA-77289
Reactome Name: Mitochondrial Fatty Acid Beta-Oxidation
See in Reactome
R-HSA-381119
R-HSA-381119
Reactome Name: Unfolded Protein Response (UPR)
See in Reactome
R-HSA-8953897
R-HSA-2262752
R-HSA-77286
R-HSA-77286
Reactome Name: mitochondrial fatty acid beta-oxidation of saturated fatty acids
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-556833
R-HSA-381070
|
Cellular responses to stimuli
Metabolism
|
R-HSA-1791069
(
R-HSA-381038
)
R-HSA-77299
(
R-HSA-77305
)
R-HSA-77299
Reaction Name: palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2
See in Reactome
|
MONDO:0008723 |
ACADVL |
P49748 |
1.3.8.9
|
R-HSA-381038
R-HSA-381038
Reactome Name: XBP1(S) activates chaperone genes
See in Reactome
R-HSA-77305
R-HSA-77305
Reactome Name: Beta oxidation of palmitoyl-CoA to myristoyl-CoA
See in Reactome
|
R-HSA-77289
R-HSA-77289
Reactome Name: Mitochondrial Fatty Acid Beta-Oxidation
See in Reactome
R-HSA-381119
R-HSA-381119
Reactome Name: Unfolded Protein Response (UPR)
See in Reactome
R-HSA-8953897
R-HSA-2262752
R-HSA-77286
R-HSA-77286
Reactome Name: mitochondrial fatty acid beta-oxidation of saturated fatty acids
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-556833
R-HSA-381070
|
Cellular responses to stimuli
Metabolism
|
R-HSA-1791069
(
R-HSA-381038
)
R-HSA-77299
(
R-HSA-77305
)
R-HSA-77299
Reaction Name: palmitoyl-CoA+FAD<=>trans-Hexadec-2-enoyl-CoA+FADH2
See in Reactome
|
MONDO:0012172 |
HADHA |
P40939 |
2.3.1.-
1.1.1.211
4.2.1.17
|
R-HSA-77288
R-HSA-77288
Reactome Name: mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
See in Reactome
R-HSA-77346
R-HSA-77346
Reactome Name: Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
See in Reactome
R-HSA-77350
R-HSA-77350
Reactome Name: Beta oxidation of hexanoyl-CoA to butanoyl-CoA
See in Reactome
R-HSA-77348
R-HSA-77348
Reactome Name: Beta oxidation of octanoyl-CoA to hexanoyl-CoA
See in Reactome
R-HSA-77310
R-HSA-77310
Reactome Name: Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
See in Reactome
R-HSA-77285
R-HSA-77285
Reactome Name: Beta oxidation of myristoyl-CoA to lauroyl-CoA
See in Reactome
R-HSA-77305
R-HSA-77305
Reactome Name: Beta oxidation of palmitoyl-CoA to myristoyl-CoA
See in Reactome
R-HSA-1482798
|
R-HSA-77289
R-HSA-77289
Reactome Name: Mitochondrial Fatty Acid Beta-Oxidation
See in Reactome
R-HSA-1483257
R-HSA-77286
R-HSA-77286
Reactome Name: mitochondrial fatty acid beta-oxidation of saturated fatty acids
See in Reactome
R-HSA-1483206
R-HSA-1483206
Reactome Name: Glycerophospholipid biosynthesis
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-556833
|
Metabolism
|
R-HSA-109339
(
R-HSA-77288
)
R-HSA-109339
Reaction Name: Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation
See in Reactome
R-HSA-109342
(
R-HSA-77288
)
R-HSA-109342
Reaction Name: Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation
See in Reactome
R-HSA-1482775
(
R-HSA-1482798
)
R-HSA-1482775
Reaction Name: MLCL is acylated to CL by HADH (IM)
See in Reactome
R-HSA-77271
(
R-HSA-77285
)
R-HSA-77271
Reaction Name: 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA
See in Reactome
R-HSA-77277
(
R-HSA-77285
)
R-HSA-77277
Reaction Name: trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA
See in Reactome
R-HSA-77283
(
R-HSA-77285
)
R-HSA-77283
Reaction Name: (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H
See in Reactome
R-HSA-77301
(
R-HSA-77305
)
R-HSA-77301
Reaction Name: trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA
See in Reactome
R-HSA-77303
(
R-HSA-77305
)
R-HSA-77303
Reaction Name: (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H
See in Reactome
R-HSA-77304
(
R-HSA-77305
)
R-HSA-77304
Reaction Name: 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA
See in Reactome
R-HSA-77309
(
R-HSA-77310
)
R-HSA-77309
Reaction Name: 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA
See in Reactome
R-HSA-77321
(
R-HSA-77350
)
R-HSA-77321
Reaction Name: 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA
See in Reactome
R-HSA-77329
(
R-HSA-77348
)
R-HSA-77329
Reaction Name: 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA
See in Reactome
R-HSA-77340
(
R-HSA-77346
)
R-HSA-77340
Reaction Name: 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA
See in Reactome
|
MONDO:0012172 |
HADHB |
P55084 |
2.3.1.16
2.3.1.155
|
R-HSA-77288
R-HSA-77288
Reactome Name: mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
See in Reactome
R-HSA-77346
R-HSA-77346
Reactome Name: Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
See in Reactome
R-HSA-77350
R-HSA-77350
Reactome Name: Beta oxidation of hexanoyl-CoA to butanoyl-CoA
See in Reactome
R-HSA-77348
R-HSA-77348
Reactome Name: Beta oxidation of octanoyl-CoA to hexanoyl-CoA
See in Reactome
R-HSA-77310
R-HSA-77310
Reactome Name: Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
See in Reactome
R-HSA-77285
R-HSA-77285
Reactome Name: Beta oxidation of myristoyl-CoA to lauroyl-CoA
See in Reactome
R-HSA-77305
R-HSA-77305
Reactome Name: Beta oxidation of palmitoyl-CoA to myristoyl-CoA
See in Reactome
R-HSA-1482798
|
R-HSA-77289
R-HSA-77289
Reactome Name: Mitochondrial Fatty Acid Beta-Oxidation
See in Reactome
R-HSA-1483257
R-HSA-77286
R-HSA-77286
Reactome Name: mitochondrial fatty acid beta-oxidation of saturated fatty acids
See in Reactome
R-HSA-1483206
R-HSA-1483206
Reactome Name: Glycerophospholipid biosynthesis
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-556833
|
Metabolism
|
R-HSA-109339
(
R-HSA-77288
)
R-HSA-109339
Reaction Name: Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation
See in Reactome
R-HSA-109342
(
R-HSA-77288
)
R-HSA-109342
Reaction Name: Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation
See in Reactome
R-HSA-1482775
(
R-HSA-1482798
)
R-HSA-1482775
Reaction Name: MLCL is acylated to CL by HADH (IM)
See in Reactome
R-HSA-77271
(
R-HSA-77285
)
R-HSA-77271
Reaction Name: 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA
See in Reactome
R-HSA-77277
(
R-HSA-77285
)
R-HSA-77277
Reaction Name: trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA
See in Reactome
R-HSA-77283
(
R-HSA-77285
)
R-HSA-77283
Reaction Name: (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H
See in Reactome
R-HSA-77301
(
R-HSA-77305
)
R-HSA-77301
Reaction Name: trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA
See in Reactome
R-HSA-77303
(
R-HSA-77305
)
R-HSA-77303
Reaction Name: (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H
See in Reactome
R-HSA-77304
(
R-HSA-77305
)
R-HSA-77304
Reaction Name: 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA
See in Reactome
R-HSA-77309
(
R-HSA-77310
)
R-HSA-77309
Reaction Name: 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA
See in Reactome
R-HSA-77321
(
R-HSA-77350
)
R-HSA-77321
Reaction Name: 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA
See in Reactome
R-HSA-77329
(
R-HSA-77348
)
R-HSA-77329
Reaction Name: 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA
See in Reactome
R-HSA-77340
(
R-HSA-77346
)
R-HSA-77340
Reaction Name: 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA
See in Reactome
|
MONDO:0012173 |
HADHA |
P40939 |
2.3.1.-
1.1.1.211
4.2.1.17
|
R-HSA-77288
R-HSA-77288
Reactome Name: mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
See in Reactome
R-HSA-77346
R-HSA-77346
Reactome Name: Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
See in Reactome
R-HSA-77350
R-HSA-77350
Reactome Name: Beta oxidation of hexanoyl-CoA to butanoyl-CoA
See in Reactome
R-HSA-77348
R-HSA-77348
Reactome Name: Beta oxidation of octanoyl-CoA to hexanoyl-CoA
See in Reactome
R-HSA-77310
R-HSA-77310
Reactome Name: Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
See in Reactome
R-HSA-77285
R-HSA-77285
Reactome Name: Beta oxidation of myristoyl-CoA to lauroyl-CoA
See in Reactome
R-HSA-77305
R-HSA-77305
Reactome Name: Beta oxidation of palmitoyl-CoA to myristoyl-CoA
See in Reactome
R-HSA-1482798
|
R-HSA-77289
R-HSA-77289
Reactome Name: Mitochondrial Fatty Acid Beta-Oxidation
See in Reactome
R-HSA-1483257
R-HSA-77286
R-HSA-77286
Reactome Name: mitochondrial fatty acid beta-oxidation of saturated fatty acids
See in Reactome
R-HSA-1483206
R-HSA-1483206
Reactome Name: Glycerophospholipid biosynthesis
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-556833
|
Metabolism
|
R-HSA-109339
(
R-HSA-77288
)
R-HSA-109339
Reaction Name: Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation
See in Reactome
R-HSA-109342
(
R-HSA-77288
)
R-HSA-109342
Reaction Name: Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation
See in Reactome
R-HSA-1482775
(
R-HSA-1482798
)
R-HSA-1482775
Reaction Name: MLCL is acylated to CL by HADH (IM)
See in Reactome
R-HSA-77271
(
R-HSA-77285
)
R-HSA-77271
Reaction Name: 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA
See in Reactome
R-HSA-77277
(
R-HSA-77285
)
R-HSA-77277
Reaction Name: trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA
See in Reactome
R-HSA-77283
(
R-HSA-77285
)
R-HSA-77283
Reaction Name: (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H
See in Reactome
R-HSA-77301
(
R-HSA-77305
)
R-HSA-77301
Reaction Name: trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA
See in Reactome
R-HSA-77303
(
R-HSA-77305
)
R-HSA-77303
Reaction Name: (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H
See in Reactome
R-HSA-77304
(
R-HSA-77305
)
R-HSA-77304
Reaction Name: 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA
See in Reactome
R-HSA-77309
(
R-HSA-77310
)
R-HSA-77309
Reaction Name: 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA
See in Reactome
R-HSA-77321
(
R-HSA-77350
)
R-HSA-77321
Reaction Name: 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA
See in Reactome
R-HSA-77329
(
R-HSA-77348
)
R-HSA-77329
Reaction Name: 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA
See in Reactome
R-HSA-77340
(
R-HSA-77346
)
R-HSA-77340
Reaction Name: 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA
See in Reactome
|
MONDO:0016573 |
HADHA |
P40939 |
2.3.1.-
1.1.1.211
4.2.1.17
|
R-HSA-77288
R-HSA-77288
Reactome Name: mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
See in Reactome
R-HSA-77346
R-HSA-77346
Reactome Name: Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
See in Reactome
R-HSA-77350
R-HSA-77350
Reactome Name: Beta oxidation of hexanoyl-CoA to butanoyl-CoA
See in Reactome
R-HSA-77348
R-HSA-77348
Reactome Name: Beta oxidation of octanoyl-CoA to hexanoyl-CoA
See in Reactome
R-HSA-77310
R-HSA-77310
Reactome Name: Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
See in Reactome
R-HSA-77285
R-HSA-77285
Reactome Name: Beta oxidation of myristoyl-CoA to lauroyl-CoA
See in Reactome
R-HSA-77305
R-HSA-77305
Reactome Name: Beta oxidation of palmitoyl-CoA to myristoyl-CoA
See in Reactome
R-HSA-1482798
|
R-HSA-77289
R-HSA-77289
Reactome Name: Mitochondrial Fatty Acid Beta-Oxidation
See in Reactome
R-HSA-1483257
R-HSA-77286
R-HSA-77286
Reactome Name: mitochondrial fatty acid beta-oxidation of saturated fatty acids
See in Reactome
R-HSA-1483206
R-HSA-1483206
Reactome Name: Glycerophospholipid biosynthesis
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-556833
|
Metabolism
|
R-HSA-109339
(
R-HSA-77288
)
R-HSA-109339
Reaction Name: Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation
See in Reactome
R-HSA-109342
(
R-HSA-77288
)
R-HSA-109342
Reaction Name: Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation
See in Reactome
R-HSA-1482775
(
R-HSA-1482798
)
R-HSA-1482775
Reaction Name: MLCL is acylated to CL by HADH (IM)
See in Reactome
R-HSA-77271
(
R-HSA-77285
)
R-HSA-77271
Reaction Name: 3-Oxotetradecanoyl-CoA+CoA-SH<=>Lauroyl-CoA
See in Reactome
R-HSA-77277
(
R-HSA-77285
)
R-HSA-77277
Reaction Name: trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA
See in Reactome
R-HSA-77283
(
R-HSA-77285
)
R-HSA-77283
Reaction Name: (S)-3-Hydroxytetradecanoyl-CoA+NAD<=>3-Oxotetradecanoyl-CoA+NADH+H
See in Reactome
R-HSA-77301
(
R-HSA-77305
)
R-HSA-77301
Reaction Name: trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA
See in Reactome
R-HSA-77303
(
R-HSA-77305
)
R-HSA-77303
Reaction Name: (S)-3-Hydroxyhexadecanoyl-CoA+NAD<=>3-Oxopalmitoyl-CoA+NADH+H
See in Reactome
R-HSA-77304
(
R-HSA-77305
)
R-HSA-77304
Reaction Name: 3-Oxopalmitoyl-CoA+CoA-SH<=>myristoyl-CoA
See in Reactome
R-HSA-77309
(
R-HSA-77310
)
R-HSA-77309
Reaction Name: 3-Oxododecanoyl-CoA+CoA-SH<=>Decanoyl-CoA
See in Reactome
R-HSA-77321
(
R-HSA-77350
)
R-HSA-77321
Reaction Name: 3-Oxohexanoyl-CoA+CoA-SH<=>Butanoyl-CoA
See in Reactome
R-HSA-77329
(
R-HSA-77348
)
R-HSA-77329
Reaction Name: 3-Oxooctanoyl-CoA+CoA-SH<=>Hexanoyl-CoA
See in Reactome
R-HSA-77340
(
R-HSA-77346
)
R-HSA-77340
Reaction Name: 3-Oxodecanoyl-CoA+CoA-SH<=>Octanoyl-CoA
See in Reactome
|