DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-77111)

Number of enzymes:	3
Number of disease:	3
Number of reactomes:	5
Number of reactions:	9

Search results (Reactome ID: R-HSA-77111)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008760	ACAT1	P24752	2.3.1.9	R-HSA-77111 R-HSA-77111 Reactome Name: Synthesis of Ketone Bodies See in Reactome R-HSA-77108 R-HSA-77108 Reactome Name: Utilization of Ketone Bodies See in Reactome R-HSA-70895 R-HSA-70895 Reactome Name: Branched-chain amino acid catabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-74182 R-HSA-74182 Reactome Name: Ketone body metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome	Metabolism	R-HSA-70844 ( R-HSA-70895 ) R-HSA-70844 Reaction Name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA See in Reactome R-HSA-73916 ( R-HSA-77111 ) R-HSA-73916 Reaction Name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA See in Reactome R-HSA-74181 ( R-HSA-77108 ) R-HSA-74181 Reaction Name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA See in Reactome
MONDO:0009520	HMGCL	P35914	4.1.3.4	R-HSA-9033241 R-HSA-9033241 Reactome Name: Peroxisomal protein import See in Reactome R-HSA-77111 R-HSA-77111 Reactome Name: Synthesis of Ketone Bodies See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-74182 R-HSA-74182 Reactome Name: Ketone body metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome	Metabolism Protein localization	R-HSA-74180 ( R-HSA-77111 ) R-HSA-74180 Reaction Name: HMG CoA => acetoacetic acid + acetyl CoA See in Reactome R-HSA-9033233 ( R-HSA-9033241 ) R-HSA-9033233 Reaction Name: PEX5S See in Reactome R-HSA-9033233 ( R-HSA-9033241 ) R-HSA-9033233 Reaction Name: PEX5S,L binds cargo proteins containing PTS1 See in Reactome R-HSA-9033235 ( R-HSA-9033241 ) R-HSA-9033235 Reaction Name: Cargo of PEX5S See in Reactome R-HSA-9033235 ( R-HSA-9033241 ) R-HSA-9033235 Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix See in Reactome R-HSA-9033236 ( R-HSA-9033241 ) R-HSA-9033236 Reaction Name: PEX5S See in Reactome R-HSA-9033236 ( R-HSA-9033241 ) R-HSA-9033236 Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) See in Reactome
MONDO:0011614	HMGCS2	P54868	2.3.3.10	R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-77111 R-HSA-77111 Reactome Name: Synthesis of Ketone Bodies See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-74182 R-HSA-74182 Reactome Name: Ketone body metabolism See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-1989760 ( R-HSA-1989781 ) R-HSA-1989760 Reaction Name: Expression of HMGCS2 See in Reactome R-HSA-73918 ( R-HSA-77111 ) R-HSA-73918 Reaction Name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH See in Reactome