DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-75876)

Number of enzymes:	9
Number of disease:	14
Number of reactomes:	5
Number of reactions:	13

Search results (Reactome ID: R-HSA-75876)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0002442	TECRL	Q5HYJ1	1.3.1.-	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism	R-HSA-548831 ( R-HSA-75876 ) R-HSA-548831 Reaction Name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA See in Reactome
MONDO:0005518	HSD17B3	P37058	1.1.1.64 1.1.1.62	R-HSA-193048 R-HSA-193048 Reactome Name: Androgen biosynthesis See in Reactome R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome	R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193064 ( R-HSA-193048 ) R-HSA-193064 Reaction Name: HSD17B3-like proteins reducde ANDST to TEST See in Reactome R-HSA-548818 ( R-HSA-75876 ) R-HSA-548818 Reaction Name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA See in Reactome
MONDO:0007574	ELOVL4	Q9GZR5	2.3.1.199	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism	R-HSA-548830 ( R-HSA-75876 ) R-HSA-548830 Reaction Name: ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA See in Reactome
MONDO:0009711	HACD1	B0YJ81	4.2.1.134	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism	R-HSA-5676637 ( R-HSA-75876 ) R-HSA-5676637 Reaction Name: PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA See in Reactome
MONDO:0009916	HSD17B3	P37058	1.1.1.64 1.1.1.62	R-HSA-193048 R-HSA-193048 Reactome Name: Androgen biosynthesis See in Reactome R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome	R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193064 ( R-HSA-193048 ) R-HSA-193064 Reaction Name: HSD17B3-like proteins reducde ANDST to TEST See in Reactome R-HSA-548818 ( R-HSA-75876 ) R-HSA-548818 Reaction Name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA See in Reactome
MONDO:0010263	ACSL4	O60488	6.2.1.15 6.2.1.3	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome R-HSA-434313 R-HSA-434313 Reactome Name: Intracellular metabolism of fatty acids regulates insulin secretion See in Reactome	R-HSA-422356 R-HSA-422356 Reactome Name: Regulation of insulin secretion See in Reactome R-HSA-400451 R-HSA-400451 Reactome Name: Free fatty acids regulate insulin secretion See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-434382 ( R-HSA-434313 ) R-HSA-434382 Reaction Name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell See in Reactome R-HSA-548843 ( R-HSA-75876 ) R-HSA-548843 Reaction Name: ACSL3,4 ligate CoA to AA to form AA-CoA See in Reactome
MONDO:0010313	ACSL4	O60488	6.2.1.15 6.2.1.3	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome R-HSA-434313 R-HSA-434313 Reactome Name: Intracellular metabolism of fatty acids regulates insulin secretion See in Reactome	R-HSA-422356 R-HSA-422356 Reactome Name: Regulation of insulin secretion See in Reactome R-HSA-400451 R-HSA-400451 Reactome Name: Free fatty acids regulate insulin secretion See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-434382 ( R-HSA-434313 ) R-HSA-434382 Reaction Name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell See in Reactome R-HSA-548843 ( R-HSA-75876 ) R-HSA-548843 Reaction Name: ACSL3,4 ligate CoA to AA to form AA-CoA See in Reactome
MONDO:0010819	ELOVL4	Q9GZR5	2.3.1.199	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism	R-HSA-548830 ( R-HSA-75876 ) R-HSA-548830 Reaction Name: ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA See in Reactome
MONDO:0013528	TECR	Q9NZ01	1.3.1.93	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism	R-HSA-548831 ( R-HSA-75876 ) R-HSA-548831 Reaction Name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA See in Reactome
MONDO:0013529	TECRL	Q5HYJ1	1.3.1.-	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism	R-HSA-548831 ( R-HSA-75876 ) R-HSA-548831 Reaction Name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA See in Reactome
MONDO:0013661	ACSF3	Q4G176	6.2.1.n3	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism	R-HSA-5696007 ( R-HSA-75876 ) R-HSA-5696007 Reaction Name: ACSF3 ligates CoA-SH to VLCFA See in Reactome
MONDO:0013760	ELOVL4	Q9GZR5	2.3.1.199	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism	R-HSA-548830 ( R-HSA-75876 ) R-HSA-548830 Reaction Name: ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA See in Reactome
MONDO:0014417	ELOVL5	Q9NYP7	2.3.1.199	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome R-HSA-2046106 R-HSA-2046106 Reactome Name: alpha-linolenic acid (ALA) metabolism See in Reactome R-HSA-2046105 R-HSA-2046105 Reactome Name: Linoleic acid (LA) metabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2046104 R-HSA-2046104 Reactome Name: alpha-linolenic (omega3) and linoleic (omega6) acid metabolism See in Reactome	Metabolism	R-HSA-2046083 ( R-HSA-2046105 ) R-HSA-2046083 Reaction Name: Elongation of arachidonyl-CoA to docosatetraenoyl-CoA See in Reactome R-HSA-2046088 ( R-HSA-2046106 ) R-HSA-2046088 Reaction Name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA See in Reactome R-HSA-2046094 ( R-HSA-2046105 ) R-HSA-2046094 Reaction Name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA See in Reactome R-HSA-2046100 ( R-HSA-2046106 ) R-HSA-2046100 Reaction Name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA See in Reactome R-HSA-548800 ( R-HSA-75876 ) R-HSA-548800 Reaction Name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA See in Reactome
MONDO:0032798	ELOVL1	Q9BW60	2.3.1.199	R-HSA-75876 R-HSA-75876 Reactome Name: Synthesis of very long-chain fatty acyl-CoAs See in Reactome R-HSA-2046106 R-HSA-2046106 Reactome Name: alpha-linolenic acid (ALA) metabolism See in Reactome R-HSA-2046105 R-HSA-2046105 Reactome Name: Linoleic acid (LA) metabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-75105 R-HSA-75105 Reactome Name: Fatty acyl-CoA biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2046104 R-HSA-2046104 Reactome Name: alpha-linolenic (omega3) and linoleic (omega6) acid metabolism See in Reactome	Metabolism	R-HSA-2046088 ( R-HSA-2046106 ) R-HSA-2046088 Reaction Name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA See in Reactome R-HSA-2046094 ( R-HSA-2046105 ) R-HSA-2046094 Reaction Name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA See in Reactome R-HSA-548800 ( R-HSA-75876 ) R-HSA-548800 Reaction Name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA See in Reactome R-HSA-548830 ( R-HSA-75876 ) R-HSA-548830 Reaction Name: ELOVL1,4 elongate TCS-CoA and Mal-CoA to 3OHC-CoA See in Reactome