DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-75109)

Number of enzymes:	5
Number of disease:	6
Number of reactomes:	6
Number of reactions:	10

Search results (Reactome ID: R-HSA-75109)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009992	LPIN1	Q14693	3.1.3.4	R-HSA-4419969 R-HSA-4419969 Reactome Name: Depolymerisation of the Nuclear Lamina See in Reactome R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-1483213 R-HSA-1483213 Reactome Name: Synthesis of PE See in Reactome R-HSA-75109 R-HSA-75109 Reactome Name: Triglyceride biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-2980766 R-HSA-2980766 Reactome Name: Nuclear Envelope Breakdown See in Reactome R-HSA-68875 R-HSA-68875 Reactome Name: Mitotic Prophase See in Reactome	Metabolism Cell Cycle	R-HSA-1483203 ( R-HSA-1483191; R-HSA-1483213 ) R-HSA-1483203 Reaction Name: PA is dephosphorylated to DAG by LPIN See in Reactome R-HSA-4419948 ( R-HSA-4419969 ) R-HSA-4419948 Reaction Name: CTDNEP1:CNEP1R1 dephosphorylates LPIN See in Reactome R-HSA-5195402 ( R-HSA-4419969 ) R-HSA-5195402 Reaction Name: CDK1 phosphorylates LPIN See in Reactome R-HSA-5221130 ( R-HSA-4419969 ) R-HSA-5221130 Reaction Name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol See in Reactome R-HSA-75899 ( R-HSA-75109 ) R-HSA-75899 Reaction Name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate See in Reactome
MONDO:0012316	LPIN2	Q92539	3.1.3.4	R-HSA-4419969 R-HSA-4419969 Reactome Name: Depolymerisation of the Nuclear Lamina See in Reactome R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-1483213 R-HSA-1483213 Reactome Name: Synthesis of PE See in Reactome R-HSA-75109 R-HSA-75109 Reactome Name: Triglyceride biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-2980766 R-HSA-2980766 Reactome Name: Nuclear Envelope Breakdown See in Reactome R-HSA-68875 R-HSA-68875 Reactome Name: Mitotic Prophase See in Reactome	Metabolism Cell Cycle	R-HSA-1483203 ( R-HSA-1483191; R-HSA-1483213 ) R-HSA-1483203 Reaction Name: PA is dephosphorylated to DAG by LPIN See in Reactome R-HSA-4419948 ( R-HSA-4419969 ) R-HSA-4419948 Reaction Name: CTDNEP1:CNEP1R1 dephosphorylates LPIN See in Reactome R-HSA-5195402 ( R-HSA-4419969 ) R-HSA-5195402 Reaction Name: CDK1 phosphorylates LPIN See in Reactome R-HSA-5221130 ( R-HSA-4419969 ) R-HSA-5221130 Reaction Name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol See in Reactome R-HSA-75899 ( R-HSA-75109 ) R-HSA-75899 Reaction Name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate See in Reactome
MONDO:0014375	DGAT1	O75907	2.3.1.20 2.3.1.76	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-1482883 R-HSA-1482883 Reactome Name: Acyl chain remodeling of DAG and TAG See in Reactome R-HSA-75109 R-HSA-75109 Reactome Name: Triglyceride biosynthesis See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Immune System Metabolism	R-HSA-1482889 ( R-HSA-1482883 ) R-HSA-1482889 Reaction Name: DAG is acylated to TAG by DGAT1/2 See in Reactome R-HSA-6799350 ( R-HSA-6798695 ) R-HSA-6799350 Reaction Name: Exocytosis of specific granule membrane proteins See in Reactome R-HSA-75900 ( R-HSA-75109 ) R-HSA-75900 Reaction Name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] See in Reactome
MONDO:0017295	GK	P32189	2.7.1.30	R-HSA-75109 R-HSA-75109 Reactome Name: Triglyceride biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome	Metabolism	R-HSA-75887 ( R-HSA-75109 ) R-HSA-75887 Reaction Name: Conversion of Glycerol to Glycerol-3-phosphate See in Reactome
MONDO:0017296	GK	P32189	2.7.1.30	R-HSA-75109 R-HSA-75109 Reactome Name: Triglyceride biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome	Metabolism	R-HSA-75887 ( R-HSA-75109 ) R-HSA-75887 Reaction Name: Conversion of Glycerol to Glycerol-3-phosphate See in Reactome
MONDO:0044625	DGAT2	Q96PD7	2.3.1.20 2.3.1.76	R-HSA-1482883 R-HSA-1482883 Reactome Name: Acyl chain remodeling of DAG and TAG See in Reactome R-HSA-75109 R-HSA-75109 Reactome Name: Triglyceride biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome	Metabolism	R-HSA-1482889 ( R-HSA-1482883 ) R-HSA-1482889 Reaction Name: DAG is acylated to TAG by DGAT1/2 See in Reactome R-HSA-549192 ( R-HSA-75109 ) R-HSA-549192 Reaction Name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] See in Reactome