DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-74217)

Number of enzymes:	9
Number of disease:	16
Number of reactomes:	3
Number of reactions:	12

Search results (Reactome ID: R-HSA-74217)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007064	ADA	P00813	3.5.4.4	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-74241 ( R-HSA-74217 ) R-HSA-74241 Reaction Name: ADA catalyzes the deamination of (deoxy)adenosine See in Reactome
MONDO:0009636	DGUOK	Q16854	2.7.1.76 2.7.1.113	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-74207 ( R-HSA-74217 ) R-HSA-74207 Reaction Name: dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) See in Reactome
MONDO:0010298	HPRT1	P00492	2.4.2.8	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-74215 ( R-HSA-74217 ) R-HSA-74215 Reaction Name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP See in Reactome
MONDO:0010299	HPRT1	P00492	2.4.2.8	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-74215 ( R-HSA-74217 ) R-HSA-74215 Reaction Name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP See in Reactome
MONDO:0011086	ADA	P00813	3.5.4.4	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-74241 ( R-HSA-74217 ) R-HSA-74241 Reaction Name: ADA catalyzes the deamination of (deoxy)adenosine See in Reactome
MONDO:0011338	ADA	P00813	3.5.4.4	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-74241 ( R-HSA-74217 ) R-HSA-74241 Reaction Name: ADA catalyzes the deamination of (deoxy)adenosine See in Reactome
MONDO:0013171	PNP	P00491	2.4.2.1	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome R-HSA-74259 R-HSA-74259 Reactome Name: Purine catabolism See in Reactome	R-HSA-8956319 R-HSA-8956319 Reactome Name: Nucleotide catabolism See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome	Immune System Metabolism	R-HSA-112033 ( R-HSA-74217 ) R-HSA-112033 Reaction Name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine See in Reactome R-HSA-112034 ( R-HSA-74217 ) R-HSA-112034 Reaction Name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine See in Reactome R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-74242 ( R-HSA-74259 ) R-HSA-74242 Reaction Name: PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose See in Reactome R-HSA-74249 ( R-HSA-74259 ) R-HSA-74249 Reaction Name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose See in Reactome
MONDO:0013869	APRT	P07741	2.4.2.7	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism Immune System	R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-74213 ( R-HSA-74217 ) R-HSA-74213 Reaction Name: APRT catalyzes the conversion of adenine to AMP See in Reactome
MONDO:0014220	AMPD1	P23109	3.5.4.6	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-76590 ( R-HSA-74217 ) R-HSA-76590 Reaction Name: AMP + H2O => IMP + NH4+ (AMPD) See in Reactome
MONDO:0014305	AMPD2	Q01433	3.5.4.6	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-76590 ( R-HSA-74217 ) R-HSA-76590 Reaction Name: AMP + H2O => IMP + NH4+ (AMPD) See in Reactome
MONDO:0014351	AMPD2	Q01433	3.5.4.6	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-76590 ( R-HSA-74217 ) R-HSA-76590 Reaction Name: AMP + H2O => IMP + NH4+ (AMPD) See in Reactome
MONDO:0014897	DGUOK	Q16854	2.7.1.76 2.7.1.113	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-74207 ( R-HSA-74217 ) R-HSA-74207 Reaction Name: dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) See in Reactome
MONDO:0014899	DGUOK	Q16854	2.7.1.76 2.7.1.113	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-74207 ( R-HSA-74217 ) R-HSA-74207 Reaction Name: dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) See in Reactome
MONDO:0020734	AMPD3	Q01432	3.5.4.6	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism Immune System	R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-76590 ( R-HSA-74217 ) R-HSA-76590 Reaction Name: AMP + H2O => IMP + NH4+ (AMPD) See in Reactome
MONDO:0100255	ADK	P55263	2.7.1.20	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-109624 ( R-HSA-74217 ) R-HSA-109624 Reaction Name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) See in Reactome
MONDO:8000013	DGUOK	Q16854	2.7.1.76 2.7.1.113	R-HSA-74217 R-HSA-74217 Reactome Name: Purine salvage See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-74207 ( R-HSA-74217 ) R-HSA-74207 Reaction Name: dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) See in Reactome