DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-73621)

Number of enzymes:	6
Number of disease:	7
Number of reactomes:	4
Number of reactions:	13

Search results (Reactome ID: R-HSA-73621)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008895	NT5E	P21589	3.1.3.5	R-HSA-196807 R-HSA-196807 Reactome Name: Nicotinate metabolism See in Reactome R-HSA-74259 R-HSA-74259 Reactome Name: Purine catabolism See in Reactome R-HSA-73621 R-HSA-73621 Reactome Name: Pyrimidine catabolism See in Reactome	R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-8956319 R-HSA-8956319 Reactome Name: Nucleotide catabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-109278 ( R-HSA-74259 ) R-HSA-109278 Reaction Name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP See in Reactome R-HSA-109291 ( R-HSA-73621 ) R-HSA-109291 Reaction Name: CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] See in Reactome R-HSA-8940070 ( R-HSA-196807 ) R-HSA-8940070 Reaction Name: NT5E:Zn2+ hydrolyses NAD+ See in Reactome R-HSA-8940074 ( R-HSA-196807 ) R-HSA-8940074 Reaction Name: NT5E:Zn2+ hydrolyses NMN See in Reactome
MONDO:0009111	DPYS	Q14117	3.5.2.2	R-HSA-73621 R-HSA-73621 Reactome Name: Pyrimidine catabolism See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8956319 R-HSA-8956319 Reactome Name: Nucleotide catabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome	Metabolism	R-HSA-73589 ( R-HSA-73621 ) R-HSA-73589 Reaction Name: 5,6-dihydrouracil + H2O => beta-ureidopropionate See in Reactome R-HSA-73618 ( R-HSA-73621 ) R-HSA-73618 Reaction Name: 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate See in Reactome
MONDO:0009946	NT5C3A	Q9H0P0	3.1.3.5 3.1.3.91	R-HSA-73621 R-HSA-73621 Reactome Name: Pyrimidine catabolism See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8956319 R-HSA-8956319 Reactome Name: Nucleotide catabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome	Metabolism	R-HSA-109449 ( R-HSA-73621 ) R-HSA-109449 Reaction Name: (d)CMP See in Reactome
MONDO:0010130	DPYD	Q12882	1.3.1.2	R-HSA-73621 R-HSA-73621 Reactome Name: Pyrimidine catabolism See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8956319 R-HSA-8956319 Reactome Name: Nucleotide catabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome	Metabolism	R-HSA-73585 ( R-HSA-73621 ) R-HSA-73585 Reaction Name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ See in Reactome R-HSA-73616 ( R-HSA-73621 ) R-HSA-73616 Reaction Name: thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ See in Reactome
MONDO:0011283	TYMP	P19971	2.4.2.4	R-HSA-73614 R-HSA-73614 Reactome Name: Pyrimidine salvage See in Reactome R-HSA-73621 R-HSA-73621 Reactome Name: Pyrimidine catabolism See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8956319 R-HSA-8956319 Reactome Name: Nucleotide catabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-112265 ( R-HSA-73621 ) R-HSA-112265 Reaction Name: thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] See in Reactome R-HSA-112266 ( R-HSA-73614 ) R-HSA-112266 Reaction Name: thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] See in Reactome
MONDO:0013164	UPB1	Q9UBR1	3.5.1.6	R-HSA-73621 R-HSA-73621 Reactome Name: Pyrimidine catabolism See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8956319 R-HSA-8956319 Reactome Name: Nucleotide catabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome	Metabolism	R-HSA-73591 ( R-HSA-73621 ) R-HSA-73591 Reaction Name: beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 See in Reactome R-HSA-73620 ( R-HSA-73621 ) R-HSA-73620 Reaction Name: beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 See in Reactome
MONDO:0017575	TYMP	P19971	2.4.2.4	R-HSA-73614 R-HSA-73614 Reactome Name: Pyrimidine salvage See in Reactome R-HSA-73621 R-HSA-73621 Reactome Name: Pyrimidine catabolism See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8956319 R-HSA-8956319 Reactome Name: Nucleotide catabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-112265 ( R-HSA-73621 ) R-HSA-112265 Reaction Name: thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] See in Reactome R-HSA-112266 ( R-HSA-73614 ) R-HSA-112266 Reaction Name: thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] See in Reactome