DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-70635)

Number of enzymes:	6
Number of disease:	8
Number of reactomes:	3
Number of reactions:	12

Search results (Reactome ID: R-HSA-70635)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008814	ARG1	P05089	3.5.3.1	R-HSA-70635 R-HSA-70635 Reactome Name: Urea cycle See in Reactome R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome	Metabolism Immune System	R-HSA-6798749 ( R-HSA-6798695 ) R-HSA-6798749 Reaction Name: Exocytosis of specific granule lumen proteins See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-70569 ( R-HSA-70635 ) R-HSA-70569 Reaction Name: arginine + H2O => ornithine + urea [ARG1] See in Reactome
MONDO:0008815	ASL	P04424	4.3.2.1	R-HSA-70635 R-HSA-70635 Reactome Name: Urea cycle See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-70573 ( R-HSA-70635 ) R-HSA-70573 Reaction Name: argininosuccinate <=> fumarate + arginine See in Reactome
MONDO:0009376	CPS1	P31327	6.3.4.16	R-HSA-70635 R-HSA-70635 Reactome Name: Urea cycle See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-70555 ( R-HSA-70635 ) R-HSA-70555 Reaction Name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] See in Reactome
MONDO:0009377	NAGS	Q8N159	2.3.1.1	R-HSA-70635 R-HSA-70635 Reactome Name: Urea cycle See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-70542 ( R-HSA-70635 ) R-HSA-70542 Reaction Name: glutamate + acetyl CoA => N-acetyl glutamate + CoA See in Reactome
MONDO:0010703	OTC	P00480	2.1.3.3	R-HSA-1268020 R-HSA-1268020 Reactome Name: Mitochondrial protein import See in Reactome R-HSA-70635 R-HSA-70635 Reactome Name: Urea cycle See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome	Metabolism Protein localization	R-HSA-1299475 ( R-HSA-1268020 ) R-HSA-1299475 Reaction Name: TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix See in Reactome R-HSA-1299478 ( R-HSA-1268020 ) R-HSA-1299478 Reaction Name: MPP cleaves targeting peptide (presequence) of matrix precursors See in Reactome R-HSA-1299480 ( R-HSA-1268020 ) R-HSA-1299480 Reaction Name: Precursor proteins enter TIMM23 PAM See in Reactome R-HSA-70560 ( R-HSA-70635 ) R-HSA-70560 Reaction Name: carbamoyl phosphate + ornithine => citrulline + orthophosphate See in Reactome R-HSA-8986181 ( R-HSA-1268020 ) R-HSA-8986181 Reaction Name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) See in Reactome
MONDO:0014151	CPS1	P31327	6.3.4.16	R-HSA-70635 R-HSA-70635 Reactome Name: Urea cycle See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-70555 ( R-HSA-70635 ) R-HSA-70555 Reaction Name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] See in Reactome
MONDO:0016600	ASS1	P00966	6.3.4.5	R-HSA-70635 R-HSA-70635 Reactome Name: Urea cycle See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-70577 ( R-HSA-70635 ) R-HSA-70577 Reaction Name: ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA See in Reactome
MONDO:0016601	ASS1	P00966	6.3.4.5	R-HSA-70635 R-HSA-70635 Reactome Name: Urea cycle See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-70577 ( R-HSA-70635 ) R-HSA-70577 Reaction Name: ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA See in Reactome