DAR - Bologna Biocomputing Group

Search results (Reactome ID: R-HSA-70263)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0004946	G6PC1	P35575	3.1.3.9	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-9615017 R-HSA-9615017 Reactome Name: FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes See in Reactome	R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism	R-HSA-71825 ( R-HSA-70263 ) R-HSA-71825 Reaction Name: G6PC hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (liver) See in Reactome R-HSA-9623192 ( R-HSA-9615017 ) R-HSA-9623192 Reaction Name: G6PC gene expression is stimulated by FOXO1,FOXO3,FOXO4,FOXO6 See in Reactome
MONDO:0005290	PGAM2	P15259	5.4.2.11 5.4.2.4	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-71445 ( R-HSA-70263 ) R-HSA-71445 Reaction Name: 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate See in Reactome R-HSA-71654 ( R-HSA-70171 ) R-HSA-71654 Reaction Name: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate See in Reactome
MONDO:0009249	ALDOB	P05062	4.1.2.13	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome R-HSA-70350 R-HSA-70350 Reactome Name: Fructose catabolism See in Reactome	R-HSA-5652084 R-HSA-5652084 Reactome Name: Fructose metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70342 ( R-HSA-70350 ) R-HSA-70342 Reaction Name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP See in Reactome R-HSA-71495 ( R-HSA-70263 ) R-HSA-71495 Reaction Name: dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate See in Reactome R-HSA-71496 ( R-HSA-70171 ) R-HSA-71496 Reaction Name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate See in Reactome
MONDO:0009251	FBP1	P09467	3.1.3.11	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70479 ( R-HSA-70263 ) R-HSA-70479 Reaction Name: D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate See in Reactome
MONDO:0009287	G6PC1	P35575	3.1.3.9	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-9615017 R-HSA-9615017 Reactome Name: FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes See in Reactome	R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism	R-HSA-71825 ( R-HSA-70263 ) R-HSA-71825 Reaction Name: G6PC hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (liver) See in Reactome R-HSA-9623192 ( R-HSA-9615017 ) R-HSA-9623192 Reaction Name: G6PC gene expression is stimulated by FOXO1,FOXO3,FOXO4,FOXO6 See in Reactome
MONDO:0009864	PCK2	Q16822	4.1.1.32	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-372819 ( R-HSA-70263 ) R-HSA-372819 Reaction Name: oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] See in Reactome
MONDO:0009865	PGAM2	P15259	5.4.2.11 5.4.2.4	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-71445 ( R-HSA-70263 ) R-HSA-71445 Reaction Name: 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate See in Reactome R-HSA-71654 ( R-HSA-70171 ) R-HSA-71654 Reaction Name: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate See in Reactome
MONDO:0009866	PCK1	P35558	4.1.1.32 2.7.11.-	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-9615017 R-HSA-9615017 Reactome Name: FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9632974 R-HSA-9632974 Reactome Name: NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis See in Reactome	R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Signal Transduction Developmental Biology	R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-70241 ( R-HSA-70263 ) R-HSA-70241 Reaction Name: oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] See in Reactome R-HSA-9605051 ( R-HSA-9632974 ) R-HSA-9605051 Reaction Name: Expression of PCK1 regulated by NR1H3 See in Reactome R-HSA-9623280 ( R-HSA-9615017 ) R-HSA-9623280 Reaction Name: PCK1 gene expression is stimulated by FOXO1:PPARGC1A See in Reactome
MONDO:0010392	PGK1	P00558	2.7.2.3	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70486 ( R-HSA-70263 ) R-HSA-70486 Reaction Name: ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate See in Reactome R-HSA-71850 ( R-HSA-70171 ) R-HSA-71850 Reaction Name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP See in Reactome
MONDO:0012747	ALDOA	P04075	4.1.2.13	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome R-HSA-114608 R-HSA-114608 Reactome Name: Platelet degranulation See in Reactome R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-76005 R-HSA-76005 Reactome Name: Response to elevated platelet cytosolic Ca2+ See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Immune System Metabolism Hemostasis	R-HSA-481007 ( R-HSA-114608 ) R-HSA-481007 Reaction Name: Exocytosis of platelet alpha granule contents See in Reactome R-HSA-6798745 ( R-HSA-6798695 ) R-HSA-6798745 Reaction Name: Exocytosis of tertiary granule lumen proteins See in Reactome R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-71495 ( R-HSA-70263 ) R-HSA-71495 Reaction Name: dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate See in Reactome R-HSA-71496 ( R-HSA-70171 ) R-HSA-71496 Reaction Name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate See in Reactome
MONDO:0012930	G6PC3	Q9BUM1	3.1.3.9	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-3262512 ( R-HSA-70263 ) R-HSA-3262512 Reaction Name: G6PC3 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (ubiquitous) See in Reactome
MONDO:0013046	ENO3	P13929	4.2.1.11	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70494 ( R-HSA-70263 ) R-HSA-70494 Reaction Name: Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate See in Reactome R-HSA-71660 ( R-HSA-70171 ) R-HSA-71660 Reaction Name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O See in Reactome
MONDO:0013275	GPI	P06744	5.3.1.9	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Immune System Metabolism Gene expression (Transcription)	R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-70471 ( R-HSA-70171 ) R-HSA-70471 Reaction Name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate See in Reactome R-HSA-70475 ( R-HSA-5628897; R-HSA-70263 ) R-HSA-70475 Reaction Name: D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate See in Reactome
MONDO:0014221	TPI1	P60174	5.3.1.1 4.2.3.3	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70454 ( R-HSA-70171 ) R-HSA-70454 Reaction Name: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate See in Reactome R-HSA-70481 ( R-HSA-70263 ) R-HSA-70481 Reaction Name: D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate See in Reactome
MONDO:0015025	MDH2	P40926	1.1.1.37	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-71403 R-HSA-71403 Reactome Name: Citric acid cycle (TCA cycle) See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-71406 R-HSA-71406 Reactome Name: Pyruvate metabolism and Citric Acid (TCA) cycle See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70979 ( R-HSA-71403 ) R-HSA-70979 Reaction Name: (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ See in Reactome R-HSA-71783 ( R-HSA-70263; R-HSA-71403 ) R-HSA-71783 Reaction Name: Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+ See in Reactome
MONDO:0017366	MDH2	P40926	1.1.1.37	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-71403 R-HSA-71403 Reactome Name: Citric acid cycle (TCA cycle) See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-71406 R-HSA-71406 Reactome Name: Pyruvate metabolism and Citric Acid (TCA) cycle See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70979 ( R-HSA-71403 ) R-HSA-70979 Reaction Name: (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ See in Reactome R-HSA-71783 ( R-HSA-70263; R-HSA-71403 ) R-HSA-71783 Reaction Name: Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+ See in Reactome
MONDO:0018141	PC	P11498	6.4.1.1	R-HSA-196780 R-HSA-196780 Reactome Name: Biotin transport and metabolism See in Reactome R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-2993802 ( R-HSA-196780 ) R-HSA-2993802 Reaction Name: HLCS biotinylates PC:Mn2+ See in Reactome R-HSA-3065959 ( R-HSA-196780 ) R-HSA-3065959 Reaction Name: An unknown protease degrades hCBXs See in Reactome R-HSA-3323111 ( R-HSA-196780 ) R-HSA-3323111 Reaction Name: Cytoslic carboxylases translocate to mitochondrial matrix See in Reactome R-HSA-70501 ( R-HSA-70263 ) R-HSA-70501 Reaction Name: Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate See in Reactome
MONDO:0018142	PC	P11498	6.4.1.1	R-HSA-196780 R-HSA-196780 Reactome Name: Biotin transport and metabolism See in Reactome R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-2993802 ( R-HSA-196780 ) R-HSA-2993802 Reaction Name: HLCS biotinylates PC:Mn2+ See in Reactome R-HSA-3065959 ( R-HSA-196780 ) R-HSA-3065959 Reaction Name: An unknown protease degrades hCBXs See in Reactome R-HSA-3323111 ( R-HSA-196780 ) R-HSA-3323111 Reaction Name: Cytoslic carboxylases translocate to mitochondrial matrix See in Reactome R-HSA-70501 ( R-HSA-70263 ) R-HSA-70501 Reaction Name: Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate See in Reactome
MONDO:0018143	PC	P11498	6.4.1.1	R-HSA-196780 R-HSA-196780 Reactome Name: Biotin transport and metabolism See in Reactome R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-2993802 ( R-HSA-196780 ) R-HSA-2993802 Reaction Name: HLCS biotinylates PC:Mn2+ See in Reactome R-HSA-3065959 ( R-HSA-196780 ) R-HSA-3065959 Reaction Name: An unknown protease degrades hCBXs See in Reactome R-HSA-3323111 ( R-HSA-196780 ) R-HSA-3323111 Reaction Name: Cytoslic carboxylases translocate to mitochondrial matrix See in Reactome R-HSA-70501 ( R-HSA-70263 ) R-HSA-70501 Reaction Name: Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate See in Reactome
MONDO:0020091	PGK1	P00558	2.7.2.3	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70486 ( R-HSA-70263 ) R-HSA-70486 Reaction Name: ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate See in Reactome R-HSA-71850 ( R-HSA-70171 ) R-HSA-71850 Reaction Name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP See in Reactome
MONDO:0030072	MDH1	P40925	1.1.1.96 1.1.1.37	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-198508 ( R-HSA-70263 ) R-HSA-198508 Reaction Name: malate + NAD+ <=> oxaloacetate + NADH + H+ See in Reactome
MONDO:0032880	GOT2	P00505	2.6.1.7 2.6.1.1	R-HSA-389661 R-HSA-389661 Reactome Name: Glyoxylate metabolism and glycine degradation See in Reactome R-HSA-8964539 R-HSA-8964539 Reactome Name: Glutamate and glutamine metabolism See in Reactome R-HSA-1614558 R-HSA-1614558 Reactome Name: Degradation of cysteine and homocysteine See in Reactome R-HSA-8963693 R-HSA-8963693 Reactome Name: Aspartate and asparagine metabolism See in Reactome R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1614635 R-HSA-1614635 Reactome Name: Sulfur amino acid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-6784393 ( R-HSA-389661 ) R-HSA-6784393 Reaction Name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) See in Reactome R-HSA-70596 ( R-HSA-8963693 ) R-HSA-70596 Reaction Name: GOT2 dimer deaminates L-Asp See in Reactome R-HSA-70613 ( R-HSA-70263; R-HSA-8964539 ) R-HSA-70613 Reaction Name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] See in Reactome R-HSA-9012597 ( R-HSA-1614558 ) R-HSA-9012597 Reaction Name: GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu See in Reactome

Number of enzymes:	16
Number of disease:	22
Number of reactomes:	15
Number of reactions:	37

Search summary (Reactome ID: R-HSA-70263)

Search results (Reactome ID: R-HSA-70263)

MONDO:0004946

R-HSA-70263

R-HSA-9615017

R-HSA-70326

R-HSA-71387

R-HSA-9614085

R-HSA-74160

R-HSA-212436

R-HSA-1430728

R-HSA-73857

R-HSA-71825

R-HSA-9623192

MONDO:0005290

R-HSA-70263

R-HSA-70171

R-HSA-1430728

R-HSA-70326

R-HSA-71387

R-HSA-71445

R-HSA-71654

MONDO:0009249

R-HSA-70263

R-HSA-70171

R-HSA-70350

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