DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-68689)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	7
Number of reactions:	14

Search results (Reactome ID: R-HSA-68689)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0044776	MCM8	Q9UJA3	3.6.4.12	R-HSA-68867 R-HSA-68867 Reactome Name: Assembly of the pre-replicative complex See in Reactome R-HSA-176974 R-HSA-176974 Reactome Name: Unwinding of DNA See in Reactome R-HSA-68962 R-HSA-68962 Reactome Name: Activation of the pre-replicative complex See in Reactome R-HSA-68689 R-HSA-68689 Reactome Name: CDC6 association with the ORC:origin complex See in Reactome R-HSA-68949 R-HSA-68949 Reactome Name: Orc1 removal from chromatin See in Reactome R-HSA-176187 R-HSA-176187 Reactome Name: Activation of ATR in response to replication stress See in Reactome R-HSA-113507 R-HSA-113507 Reactome Name: E2F-enabled inhibition of pre-replication complex formation See in Reactome	R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-69052 R-HSA-69052 Reactome Name: Switching of origins to a post-replicative state See in Reactome R-HSA-69481 R-HSA-69481 Reactome Name: G2/M Checkpoints See in Reactome R-HSA-69206 R-HSA-69206 Reactome Name: G1/S Transition See in Reactome R-HSA-69242 R-HSA-69242 Reactome Name: S Phase See in Reactome R-HSA-69306 R-HSA-69306 Reactome Name: DNA Replication See in Reactome R-HSA-69190 R-HSA-69190 Reactome Name: DNA strand elongation See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-69002 R-HSA-69002 Reactome Name: DNA Replication Pre-Initiation See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-113510 R-HSA-113510 Reactome Name: E2F mediated regulation of DNA replication See in Reactome R-HSA-69620 R-HSA-69620 Reactome Name: Cell Cycle Checkpoints See in Reactome R-HSA-69239 R-HSA-69239 Reactome Name: Synthesis of DNA See in Reactome	DNA Replication Cell Cycle	R-HSA-113638 ( R-HSA-113507 ) R-HSA-113638 Reaction Name: Association of Cyclin B/Cdk1 with replicative origin inhibits pre-RC formation See in Reactome R-HSA-169461 ( R-HSA-176974 ) R-HSA-169461 Reaction Name: MCM8 mediated fork unwinding See in Reactome R-HSA-176298 ( R-HSA-176187 ) R-HSA-176298 Reaction Name: Activation of claspin See in Reactome R-HSA-176318 ( R-HSA-176187 ) R-HSA-176318 Reaction Name: Loading of claspin onto DNA during replication origin firing See in Reactome R-HSA-68688 ( R-HSA-68689; R-HSA-68867 ) R-HSA-68688 Reaction Name: CDC6 association with ORC(1-6) at replication origins See in Reactome R-HSA-68914 ( R-HSA-68962 ) R-HSA-68914 Reaction Name: DNA polymerase alpha:primase binds at the origin See in Reactome R-HSA-68916 ( R-HSA-68962 ) R-HSA-68916 Reaction Name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin See in Reactome R-HSA-68917 ( R-HSA-68962 ) R-HSA-68917 Reaction Name: Cdc45 associates with the pre-replicative complex at the origin See in Reactome R-HSA-68918 ( R-HSA-68962 ) R-HSA-68918 Reaction Name: CDK and DDK associate with the Mcm10:pre-replicative complex See in Reactome R-HSA-68919 ( R-HSA-68962 ) R-HSA-68919 Reaction Name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 See in Reactome R-HSA-68940 ( R-HSA-68962 ) R-HSA-68940 Reaction Name: Cdt1 is displaced from the pre-replicative complex. See in Reactome R-HSA-68944 ( R-HSA-68949 ) R-HSA-68944 Reaction Name: Orc1 is phosphorylated by cyclin A/CDK2 See in Reactome R-HSA-68960 ( R-HSA-68962 ) R-HSA-68960 Reaction Name: DNA polymerase epsilon binds at the origin See in Reactome R-HSA-9749215 ( R-HSA-68689; R-HSA-68867 ) R-HSA-9749215 Reaction Name: MCM8 binds CDC6 See in Reactome