DAR - Bologna Biocomputing Group

Search results (Reactome ID: R-HSA-6782315)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0000208	TRMT10A	Q8TBZ6	2.1.1.221	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6786621 ( R-HSA-6782315 ) R-HSA-6786621 Reaction Name: TRMT10A methylates guanosine-9 in tRNA See in Reactome
MONDO:0000819	PUS3	Q9BZE2	5.4.99.45	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-8870289 ( R-HSA-6782315 ) R-HSA-8870289 Reaction Name: PUS3 transforms uridine-39 to pseudouridine-39 in tRNA See in Reactome
MONDO:0004585	PUS3	Q9BZE2	5.4.99.45	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-8870289 ( R-HSA-6782315 ) R-HSA-8870289 Reaction Name: PUS3 transforms uridine-39 to pseudouridine-39 in tRNA See in Reactome
MONDO:0005148	CDKAL1	Q5VV42	2.8.4.5	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6786571 ( R-HSA-6782315 ) R-HSA-6786571 Reaction Name: CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 See in Reactome
MONDO:0009072	PUS3	Q9BZE2	5.4.99.45	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-8870289 ( R-HSA-6782315 ) R-HSA-8870289 Reaction Name: PUS3 transforms uridine-39 to pseudouridine-39 in tRNA See in Reactome
MONDO:0009124	NSUN2	Q08J23	2.1.1.203 2.1.1.-	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6782388 ( R-HSA-6782315 ) R-HSA-6782388 Reaction Name: NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) See in Reactome R-HSA-6785409 ( R-HSA-6782315 ) R-HSA-6785409 Reaction Name: NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) See in Reactome R-HSA-6785438 ( R-HSA-6782315 ) R-HSA-6785438 Reaction Name: NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) See in Reactome
MONDO:0009327	PUS3	Q9BZE2	5.4.99.45	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-8870289 ( R-HSA-6782315 ) R-HSA-8870289 Reaction Name: PUS3 transforms uridine-39 to pseudouridine-39 in tRNA See in Reactome
MONDO:0010660	FTSJ1	Q9UET6	2.1.1.205	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-9024159 ( R-HSA-6782315 ) R-HSA-9024159 Reaction Name: FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe) See in Reactome R-HSA-9024161 ( R-HSA-6782315 ) R-HSA-9024161 Reaction Name: FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe) See in Reactome
MONDO:0012613	NSUN2	Q08J23	2.1.1.203 2.1.1.-	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6782388 ( R-HSA-6782315 ) R-HSA-6782388 Reaction Name: NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) See in Reactome R-HSA-6785409 ( R-HSA-6782315 ) R-HSA-6785409 Reaction Name: NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) See in Reactome R-HSA-6785438 ( R-HSA-6782315 ) R-HSA-6785438 Reaction Name: NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) See in Reactome
MONDO:0014886	PUS3	Q9BZE2	5.4.99.45	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-8870289 ( R-HSA-6782315 ) R-HSA-8870289 Reaction Name: PUS3 transforms uridine-39 to pseudouridine-39 in tRNA See in Reactome
MONDO:0018320	TRMT10A	Q8TBZ6	2.1.1.221	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6786621 ( R-HSA-6782315 ) R-HSA-6786621 Reaction Name: TRMT10A methylates guanosine-9 in tRNA See in Reactome
MONDO:0024553	PUS1	Q9Y606	5.4.99.12	R-HSA-6787450 R-HSA-6787450 Reactome Name: tRNA modification in the mitochondrion See in Reactome R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6782381 ( R-HSA-6782315 ) R-HSA-6782381 Reaction Name: PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAs See in Reactome R-HSA-6787566 ( R-HSA-6787450 ) R-HSA-6787566 Reaction Name: PUS1 isoform 1 transforms uridine-27 See in Reactome
MONDO:0032665	TRMT1	Q9NXH9	2.1.1.216	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6782416 ( R-HSA-6782315 ) R-HSA-6782416 Reaction Name: TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) See in Reactome
MONDO:0032687	PUS7	Q96PZ0	5.4.99.-	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6786583 ( R-HSA-6782315 ) R-HSA-6786583 Reaction Name: PUS7 transforms uridine to pseudouridine in tRNAs See in Reactome
MONDO:0032789	ALKBH8	Q96BT7	2.1.1.229	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6786500 ( R-HSA-6782315 ) R-HSA-6786500 Reaction Name: ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 See in Reactome
MONDO:0032923	THG1L	Q9NWX6	2.7.7.79	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6782434 ( R-HSA-6782315 ) R-HSA-6782434 Reaction Name: THG1L transfers GMP to 5' end of tRNA(His) See in Reactome
MONDO:0033007	OSGEP	Q9NPF4	2.3.1.234	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6784494 ( R-HSA-6782315 ) R-HSA-6784494 Reaction Name: EKC complex threonylcarbamoylates A37 of tRNAs See in Reactome
MONDO:0033008	TP53RK	Q96S44	3.6.-.- 2.7.11.1	R-HSA-6804756 R-HSA-6804756 Reactome Name: Regulation of TP53 Activity through Phosphorylation See in Reactome R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism of RNA	R-HSA-6784494 ( R-HSA-6782315 ) R-HSA-6784494 Reaction Name: EKC complex threonylcarbamoylates A37 of tRNAs See in Reactome R-HSA-6805479 ( R-HSA-6804756 ) R-HSA-6805479 Reaction Name: TP53RK phosphorylates TP53 See in Reactome
MONDO:0054742	TRIT1	Q9H3H1	2.5.1.75	R-HSA-6787450 R-HSA-6787450 Reactome Name: tRNA modification in the mitochondrion See in Reactome R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6784462 ( R-HSA-6782315 ) R-HSA-6784462 Reaction Name: TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs See in Reactome R-HSA-6787567 ( R-HSA-6787450 ) R-HSA-6787567 Reaction Name: TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) See in Reactome
MONDO:0054782	EPRS1	P07814	6.1.1.17 6.1.1.15	R-HSA-379716 R-HSA-379716 Reactome Name: Cytosolic tRNA aminoacylation See in Reactome R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome R-HSA-2408522 R-HSA-2408522 Reactome Name: Selenoamino acid metabolism See in Reactome	R-HSA-379724 R-HSA-379724 Reactome Name: tRNA Aminoacylation See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-72766 R-HSA-72766 Reactome Name: Translation See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome	Metabolism of RNA Metabolism of proteins Metabolism	R-HSA-2408546 ( R-HSA-2408522 ) R-HSA-2408546 Reaction Name: tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex See in Reactome R-HSA-379861 ( R-HSA-379716 ) R-HSA-379861 Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate See in Reactome R-HSA-379865 ( R-HSA-379716 ) R-HSA-379865 Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate See in Reactome R-HSA-379867 ( R-HSA-379716 ) R-HSA-379867 Reaction Name: aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate See in Reactome R-HSA-379893 ( R-HSA-379716 ) R-HSA-379893 Reaction Name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate See in Reactome R-HSA-379974 ( R-HSA-379716 ) R-HSA-379974 Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate See in Reactome R-HSA-379982 ( R-HSA-379716 ) R-HSA-379982 Reaction Name: glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate See in Reactome R-HSA-379993 ( R-HSA-379716 ) R-HSA-379993 Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate See in Reactome R-HSA-379994 ( R-HSA-379716 ) R-HSA-379994 Reaction Name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate See in Reactome R-HSA-380008 ( R-HSA-379716 ) R-HSA-380008 Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate See in Reactome R-HSA-6782296 ( R-HSA-6782315 ) R-HSA-6782296 Reaction Name: DUS2:EPRS reduces uridine to dihydrouridine in tRNAs See in Reactome
MONDO:0060596	PUS7	Q96PZ0	5.4.99.-	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6786583 ( R-HSA-6782315 ) R-HSA-6786583 Reaction Name: PUS7 transforms uridine to pseudouridine in tRNAs See in Reactome
MONDO:0060596	TRMT1	Q9NXH9	2.1.1.216	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6782416 ( R-HSA-6782315 ) R-HSA-6782416 Reaction Name: TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) See in Reactome

Number of enzymes:	14
Number of disease:	21
Number of reactomes:	5
Number of reactions:	29

Search summary (Reactome ID: R-HSA-6782315)

Search results (Reactome ID: R-HSA-6782315)

MONDO:0000208

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-6786621

MONDO:0000819

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-8870289

MONDO:0004585

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-8870289

MONDO:0005148

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-6786571

MONDO:0009072

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-8870289

MONDO:0009124

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-6782388

R-HSA-6785409

R-HSA-6785438

MONDO:0009327

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-8870289

MONDO:0010660

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-9024159

R-HSA-9024161

MONDO:0012613

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-6782388

R-HSA-6785409

R-HSA-6785438

MONDO:0014886

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-8870289

MONDO:0018320

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-6786621

MONDO:0024553

R-HSA-6787450

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-6782381

R-HSA-6787566

MONDO:0032665

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-6782416

MONDO:0032687

R-HSA-6782315

R-HSA-72306

R-HSA-8953854

R-HSA-6786583

MONDO:0032789