DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-5662702)

Number of enzymes:	3
Number of disease:	9
Number of reactomes:	1
Number of reactions:	5

Search results (Reactome ID: R-HSA-5662702)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0001384	TYR	P14679	1.14.18.1	R-HSA-5662702 R-HSA-5662702 Reactome Name: Melanin biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5662662 ( R-HSA-5662702 ) R-HSA-5662662 Reaction Name: Tyrosinase oxidises tyrosine to dopaquinone See in Reactome R-HSA-5662692 ( R-HSA-5662702 ) R-HSA-5662692 Reaction Name: Dopa is oxidized to dopaquinone by TYR See in Reactome R-HSA-5663050 ( R-HSA-5662702 ) R-HSA-5663050 Reaction Name: DHI and DHICA polymerise forming eumelanin See in Reactome
MONDO:0005712	TYR	P14679	1.14.18.1	R-HSA-5662702 R-HSA-5662702 Reactome Name: Melanin biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5662662 ( R-HSA-5662702 ) R-HSA-5662662 Reaction Name: Tyrosinase oxidises tyrosine to dopaquinone See in Reactome R-HSA-5662692 ( R-HSA-5662702 ) R-HSA-5662692 Reaction Name: Dopa is oxidized to dopaquinone by TYR See in Reactome R-HSA-5663050 ( R-HSA-5662702 ) R-HSA-5663050 Reaction Name: DHI and DHICA polymerise forming eumelanin See in Reactome
MONDO:0008747	TYRP1	P17643	1.14.18.-	R-HSA-5662702 R-HSA-5662702 Reactome Name: Melanin biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-8878581 ( R-HSA-5662702 ) R-HSA-8878581 Reaction Name: TYRP1 oxidises DHICA to IQCA See in Reactome
MONDO:0011749	TYR	P14679	1.14.18.1	R-HSA-5662702 R-HSA-5662702 Reactome Name: Melanin biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5662662 ( R-HSA-5662702 ) R-HSA-5662662 Reaction Name: Tyrosinase oxidises tyrosine to dopaquinone See in Reactome R-HSA-5662692 ( R-HSA-5662702 ) R-HSA-5662692 Reaction Name: Dopa is oxidized to dopaquinone by TYR See in Reactome R-HSA-5663050 ( R-HSA-5662702 ) R-HSA-5663050 Reaction Name: DHI and DHICA polymerise forming eumelanin See in Reactome
MONDO:0017304	TYRP1	P17643	1.14.18.-	R-HSA-5662702 R-HSA-5662702 Reactome Name: Melanin biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-8878581 ( R-HSA-5662702 ) R-HSA-8878581 Reaction Name: TYRP1 oxidises DHICA to IQCA See in Reactome
MONDO:0018136	TYR	P14679	1.14.18.1	R-HSA-5662702 R-HSA-5662702 Reactome Name: Melanin biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5662662 ( R-HSA-5662702 ) R-HSA-5662662 Reaction Name: Tyrosinase oxidises tyrosine to dopaquinone See in Reactome R-HSA-5662692 ( R-HSA-5662702 ) R-HSA-5662692 Reaction Name: Dopa is oxidized to dopaquinone by TYR See in Reactome R-HSA-5663050 ( R-HSA-5662702 ) R-HSA-5663050 Reaction Name: DHI and DHICA polymerise forming eumelanin See in Reactome
MONDO:0018137	TYR	P14679	1.14.18.1	R-HSA-5662702 R-HSA-5662702 Reactome Name: Melanin biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5662662 ( R-HSA-5662702 ) R-HSA-5662662 Reaction Name: Tyrosinase oxidises tyrosine to dopaquinone See in Reactome R-HSA-5662692 ( R-HSA-5662702 ) R-HSA-5662692 Reaction Name: Dopa is oxidized to dopaquinone by TYR See in Reactome R-HSA-5663050 ( R-HSA-5662702 ) R-HSA-5663050 Reaction Name: DHI and DHICA polymerise forming eumelanin See in Reactome
MONDO:0018138	TYR	P14679	1.14.18.1	R-HSA-5662702 R-HSA-5662702 Reactome Name: Melanin biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5662662 ( R-HSA-5662702 ) R-HSA-5662662 Reaction Name: Tyrosinase oxidises tyrosine to dopaquinone See in Reactome R-HSA-5662692 ( R-HSA-5662702 ) R-HSA-5662692 Reaction Name: Dopa is oxidized to dopaquinone by TYR See in Reactome R-HSA-5663050 ( R-HSA-5662702 ) R-HSA-5663050 Reaction Name: DHI and DHICA polymerise forming eumelanin See in Reactome
MONDO:0030899	DCT	P40126	5.3.3.12	R-HSA-5662702 R-HSA-5662702 Reactome Name: Melanin biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5662660 ( R-HSA-5662702 ) R-HSA-5662660 Reaction Name: Dopachrome is transformed to DHICA by DCT See in Reactome