DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-5423646)

Number of enzymes:	3
Number of disease:	3
Number of reactomes:	5
Number of reactions:	11

Search results (Reactome ID: R-HSA-5423646)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009285	GGT1	P19440	3.4.19.14 2.3.2.2 3.4.19.13	R-HSA-174403 R-HSA-174403 Reactome Name: Glutathione synthesis and recycling See in Reactome R-HSA-2142691 R-HSA-2142691 Reactome Name: Synthesis of Leukotrienes (LT) and Eoxins (EX) See in Reactome R-HSA-5423646 R-HSA-5423646 Reactome Name: Aflatoxin activation and detoxification See in Reactome	R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-156590 R-HSA-156590 Reactome Name: Glutathione conjugation See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-266046 ( R-HSA-2142691 ) R-HSA-266046 Reaction Name: GGT1, 5 dimers hydrolyse LTC4 to LTD4 See in Reactome R-HSA-5433072 ( R-HSA-5423646 ) R-HSA-5433072 Reaction Name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG See in Reactome R-HSA-8943279 ( R-HSA-174403 ) R-HSA-8943279 Reaction Name: GGT dimers hydrolyse GSH See in Reactome
MONDO:0012368	ACY1	Q03154	3.5.1.14	R-HSA-5423646 R-HSA-5423646 Reactome Name: Aflatoxin activation and detoxification See in Reactome	R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5433074 ( R-HSA-5423646 ) R-HSA-5433074 Reaction Name: ACY1:Zn2+ dimer hydrolyses mercapturic acids See in Reactome
MONDO:0033640	CYP3A4	P08684	1.14.14.55 1.14.14.56 1.14.14.1 1.14.14.73	R-HSA-5423646 R-HSA-5423646 Reactome Name: Aflatoxin activation and detoxification See in Reactome R-HSA-211981 R-HSA-211981 Reactome Name: Xenobiotics See in Reactome R-HSA-9027307 R-HSA-9027307 Reactome Name: Biosynthesis of maresin-like SPMs See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-9018677 R-HSA-9018677 Reactome Name: Biosynthesis of DHA-derived SPMs See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9018682 R-HSA-9018682 Reactome Name: Biosynthesis of maresins See in Reactome R-HSA-9018678 R-HSA-9018678 Reactome Name: Biosynthesis of specialized proresolving mediators (SPMs) See in Reactome	Metabolism	R-HSA-156526 ( R-HSA-5423646 ) R-HSA-156526 Reaction Name: CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO See in Reactome R-HSA-211882 ( R-HSA-211981 ) R-HSA-211882 Reaction Name: CYP3A7 can 6beta-hydroxylate testosterone See in Reactome R-HSA-211948 ( R-HSA-211981 ) R-HSA-211948 Reaction Name: CYP3A4 can N-demethylate loperamide See in Reactome R-HSA-213175 ( R-HSA-211981 ) R-HSA-213175 Reaction Name: CYP3A4,5 oxidise AFB1 to AFXBO See in Reactome R-HSA-5423664 ( R-HSA-5423646 ) R-HSA-5423664 Reaction Name: CYP3A4,5 hydroxylates AFB1 to AFQ1 See in Reactome R-HSA-5423672 ( R-HSA-5423646 ) R-HSA-5423672 Reaction Name: CYP1A2, 3A4 oxidise AFB1 to AFNBO See in Reactome R-HSA-9027043 ( R-HSA-9027307 ) R-HSA-9027043 Reaction Name: CYPs hydroxylate DHA to 14(R)-HDHA See in Reactome