DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-5368286)

Number of enzymes:	2
Number of disease:	4
Number of reactomes:	3
Number of reactions:	12

Search results (Reactome ID: R-HSA-5368286)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013987	MTFMT	Q96DP5	2.1.2.9	R-HSA-5368286 R-HSA-5368286 Reactome Name: Mitochondrial translation initiation See in Reactome	R-HSA-5368287 R-HSA-5368287 Reactome Name: Mitochondrial translation See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-72766 R-HSA-72766 Reactome Name: Translation See in Reactome	Metabolism of proteins	R-HSA-5389841 ( R-HSA-5368286 ) R-HSA-5389841 Reaction Name: MTFMT formylates methionyl-tRNA See in Reactome
MONDO:0014162	MRPL44	Q9H9J2	3.1.26.-	R-HSA-5389840 R-HSA-5389840 Reactome Name: Mitochondrial translation elongation See in Reactome R-HSA-5368286 R-HSA-5368286 Reactome Name: Mitochondrial translation initiation See in Reactome R-HSA-5419276 R-HSA-5419276 Reactome Name: Mitochondrial translation termination See in Reactome	R-HSA-5368287 R-HSA-5368287 Reactome Name: Mitochondrial translation See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-72766 R-HSA-72766 Reactome Name: Translation See in Reactome	Metabolism of proteins	R-HSA-5389839 ( R-HSA-5368286 ) R-HSA-5389839 Reaction Name: 39S subunit binds 28S subunit:mRNA:fMet-tRNA See in Reactome R-HSA-5389842 ( R-HSA-5389840 ) R-HSA-5389842 Reaction Name: TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome See in Reactome R-HSA-5389848 ( R-HSA-5389840 ) R-HSA-5389848 Reaction Name: TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA See in Reactome R-HSA-5389857 ( R-HSA-5389840 ) R-HSA-5389857 Reaction Name: Peptide transfer from P-site to A-site (peptide bond formation) See in Reactome R-HSA-5419261 ( R-HSA-5389840 ) R-HSA-5419261 Reaction Name: 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP See in Reactome R-HSA-5419264 ( R-HSA-5419276 ) R-HSA-5419264 Reaction Name: MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA See in Reactome R-HSA-5419271 ( R-HSA-5419276 ) R-HSA-5419271 Reaction Name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP See in Reactome R-HSA-5419273 ( R-HSA-5419276 ) R-HSA-5419273 Reaction Name: Hydrolysis of GTP and dissociation of 28S and 39S subunits See in Reactome R-HSA-5419277 ( R-HSA-5419276 ) R-HSA-5419277 Reaction Name: GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA See in Reactome R-HSA-5419279 ( R-HSA-5389840 ) R-HSA-5419279 Reaction Name: Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) See in Reactome R-HSA-5419281 ( R-HSA-5419276 ) R-HSA-5419281 Reaction Name: MRRF binds 55S ribosome:mRNA:tRNA See in Reactome
MONDO:0016815	MTFMT	Q96DP5	2.1.2.9	R-HSA-5368286 R-HSA-5368286 Reactome Name: Mitochondrial translation initiation See in Reactome	R-HSA-5368287 R-HSA-5368287 Reactome Name: Mitochondrial translation See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-72766 R-HSA-72766 Reactome Name: Translation See in Reactome	Metabolism of proteins	R-HSA-5389841 ( R-HSA-5368286 ) R-HSA-5389841 Reaction Name: MTFMT formylates methionyl-tRNA See in Reactome
MONDO:0032631	MTFMT	Q96DP5	2.1.2.9	R-HSA-5368286 R-HSA-5368286 Reactome Name: Mitochondrial translation initiation See in Reactome	R-HSA-5368287 R-HSA-5368287 Reactome Name: Mitochondrial translation See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-72766 R-HSA-72766 Reactome Name: Translation See in Reactome	Metabolism of proteins	R-HSA-5389841 ( R-HSA-5368286 ) R-HSA-5389841 Reaction Name: MTFMT formylates methionyl-tRNA See in Reactome