DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-5365859)

Number of enzymes:	5
Number of disease:	6
Number of reactomes:	4
Number of reactions:	9

Search results (Reactome ID: R-HSA-5365859)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0005260	ALDH1A3	P47895	1.2.1.36	R-HSA-5365859 R-HSA-5365859 Reactome Name: RA biosynthesis pathway See in Reactome	R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5362517 R-HSA-5362517 Reactome Name: Signaling by Retinoic Acid See in Reactome	Signal Transduction	R-HSA-5362522 ( R-HSA-5365859 ) R-HSA-5362522 Reaction Name: ALDHs oxidise atRAL to atRA See in Reactome
MONDO:0013740	CYP26B1	Q9NR63	1.14.13.-	R-HSA-5365859 R-HSA-5365859 Reactome Name: RA biosynthesis pathway See in Reactome R-HSA-211916 R-HSA-211916 Reactome Name: Vitamins See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5362517 R-HSA-5362517 Reactome Name: Signaling by Retinoic Acid See in Reactome	Metabolism Signal Transduction	R-HSA-212007 ( R-HSA-211916 ) R-HSA-212007 Reaction Name: CYP26A1,B1 4-hydroxylate atRA See in Reactome R-HSA-5362525 ( R-HSA-5365859 ) R-HSA-5362525 Reaction Name: CYP26A1,B1,C1 4-hydroxylate atRA See in Reactome
MONDO:0013997	CYP26C1	Q6V0L0	1.14.-.-	R-HSA-5365859 R-HSA-5365859 Reactome Name: RA biosynthesis pathway See in Reactome R-HSA-211916 R-HSA-211916 Reactome Name: Vitamins See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5362517 R-HSA-5362517 Reactome Name: Signaling by Retinoic Acid See in Reactome	Metabolism Signal Transduction	R-HSA-211923 ( R-HSA-211916; R-HSA-5365859 ) R-HSA-211923 Reaction Name: CYP26C1 4-hydroxylates 9cRA See in Reactome R-HSA-212007 ( R-HSA-211916 ) R-HSA-212007 Reaction Name: CYP26A1,B1 4-hydroxylate atRA See in Reactome R-HSA-5362525 ( R-HSA-5365859 ) R-HSA-5362525 Reaction Name: CYP26A1,B1,C1 4-hydroxylate atRA See in Reactome
MONDO:0014050	ALDH1A3	P47895	1.2.1.36	R-HSA-5365859 R-HSA-5365859 Reactome Name: RA biosynthesis pathway See in Reactome	R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5362517 R-HSA-5362517 Reactome Name: Signaling by Retinoic Acid See in Reactome	Signal Transduction	R-HSA-5362522 ( R-HSA-5365859 ) R-HSA-5362522 Reaction Name: ALDHs oxidise atRAL to atRA See in Reactome
MONDO:0014495	RDH11	Q8TC12	1.1.1.300	R-HSA-5365859 R-HSA-5365859 Reactome Name: RA biosynthesis pathway See in Reactome R-HSA-975634 R-HSA-975634 Reactome Name: Retinoid metabolism and transport See in Reactome R-HSA-2453902 R-HSA-2453902 Reactome Name: The canonical retinoid cycle in rods (twilight vision) See in Reactome	R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-6806667 R-HSA-6806667 Reactome Name: Metabolism of fat-soluble vitamins See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5362517 R-HSA-5362517 Reactome Name: Signaling by Retinoic Acid See in Reactome	Sensory Perception Metabolism Signal Transduction	R-HSA-5362721 ( R-HSA-5365859 ) R-HSA-5362721 Reaction Name: RDH5,RDH11 oxidise 11cROL to 11cRAL See in Reactome R-HSA-5419165 ( R-HSA-5365859 ) R-HSA-5419165 Reaction Name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL See in Reactome R-HSA-74872 ( R-HSA-2453902 ) R-HSA-74872 Reaction Name: RDH10,11 oxidise 11cROL to 11cRAL See in Reactome R-HSA-975629 ( R-HSA-975634 ) R-HSA-975629 Reaction Name: RDH11 reduces RBP2:atRAL to RBP2:atROL See in Reactome
MONDO:0018877	RDH5	Q92781	1.1.1.209 1.1.1.53 1.1.1.315	R-HSA-5365859 R-HSA-5365859 Reactome Name: RA biosynthesis pathway See in Reactome R-HSA-2453902 R-HSA-2453902 Reactome Name: The canonical retinoid cycle in rods (twilight vision) See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-5362517 R-HSA-5362517 Reactome Name: Signaling by Retinoic Acid See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome	Sensory Perception Signal Transduction	R-HSA-2454081 ( R-HSA-2453902 ) R-HSA-2454081 Reaction Name: RDH5 oxidises 11cROL to 11cRAL See in Reactome R-HSA-5362721 ( R-HSA-5365859 ) R-HSA-5362721 Reaction Name: RDH5,RDH11 oxidise 11cROL to 11cRAL See in Reactome