DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-446199)

Number of enzymes:	5
Number of disease:	10
Number of reactomes:	4
Number of reactions:	6

Search results (Reactome ID: R-HSA-446199)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0012556	DOLK	Q9UPQ8	2.7.1.108	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-446195 ( R-HSA-446199 ) R-HSA-446195 Reaction Name: DOLK phosphorylates DCHOL to DOLP See in Reactome
MONDO:0012885	SRD5A3	Q9H8P0	1.3.1.22 1.3.1.94	R-HSA-193048 R-HSA-193048 Reactome Name: Androgen biosynthesis See in Reactome R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism of proteins Metabolism	R-HSA-4419979 ( R-HSA-446199 ) R-HSA-4419979 Reaction Name: SRD5A3 reduces pPNOL to DCHOL See in Reactome R-HSA-9705714 ( R-HSA-193048 ) R-HSA-9705714 Reaction Name: SRD5A3 dehydrogenates TEST to DHTEST See in Reactome
MONDO:0012991	SRD5A3	Q9H8P0	1.3.1.22 1.3.1.94	R-HSA-193048 R-HSA-193048 Reactome Name: Androgen biosynthesis See in Reactome R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism of proteins Metabolism	R-HSA-4419979 ( R-HSA-446199 ) R-HSA-4419979 Reaction Name: SRD5A3 reduces pPNOL to DCHOL See in Reactome R-HSA-9705714 ( R-HSA-193048 ) R-HSA-9705714 Reaction Name: SRD5A3 dehydrogenates TEST to DHTEST See in Reactome
MONDO:0013468	DHDDS	Q86SQ9	2.5.1.87	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-4419978 ( R-HSA-446199 ) R-HSA-4419978 Reaction Name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP See in Reactome
MONDO:0013868	MVD	P53602	4.1.1.33	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism of proteins Metabolism	R-HSA-1655836 ( R-HSA-2426168 ) R-HSA-1655836 Reaction Name: Expression of Diphosphomevalonate Decarboxylase (MVD) See in Reactome R-HSA-191414 ( R-HSA-191273; R-HSA-446199 ) R-HSA-191414 Reaction Name: MVD decarboxylates MVA5PP to IPPP See in Reactome
MONDO:0014904	NUS1	Q96E22	2.5.1.87	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-4419978 ( R-HSA-446199 ) R-HSA-4419978 Reaction Name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP See in Reactome
MONDO:0015470	DOLK	Q9UPQ8	2.7.1.108	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-446195 ( R-HSA-446199 ) R-HSA-446195 Reaction Name: DOLK phosphorylates DCHOL to DOLP See in Reactome
MONDO:0018614	DHDDS	Q86SQ9	2.5.1.87	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-4419978 ( R-HSA-446199 ) R-HSA-4419978 Reaction Name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP See in Reactome
MONDO:0018614	NUS1	Q96E22	2.5.1.87	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-4419978 ( R-HSA-446199 ) R-HSA-4419978 Reaction Name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP See in Reactome
MONDO:0030921	NUS1	Q96E22	2.5.1.87	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-4419978 ( R-HSA-446199 ) R-HSA-4419978 Reaction Name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP See in Reactome
MONDO:0044326	DHDDS	Q86SQ9	2.5.1.87	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-4419978 ( R-HSA-446199 ) R-HSA-4419978 Reaction Name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP See in Reactome