DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-422085)

Number of enzymes:	3
Number of disease:	5
Number of reactomes:	7
Number of reactions:	8

Search results (Reactome ID: R-HSA-422085)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007817	PLA2G7	Q13093	3.1.1.47	R-HSA-422085 R-HSA-422085 Reactome Name: Synthesis, secretion, and deacylation of Ghrelin See in Reactome	R-HSA-2980736 R-HSA-2980736 Reactome Name: Peptide hormone metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome	Metabolism of proteins	R-HSA-9023619 ( R-HSA-422085 ) R-HSA-9023619 Reaction Name: Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin See in Reactome
MONDO:0010940	PLA2G7	Q13093	3.1.1.47	R-HSA-422085 R-HSA-422085 Reactome Name: Synthesis, secretion, and deacylation of Ghrelin See in Reactome	R-HSA-2980736 R-HSA-2980736 Reactome Name: Peptide hormone metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome	Metabolism of proteins	R-HSA-9023619 ( R-HSA-422085 ) R-HSA-9023619 Reaction Name: Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin See in Reactome
MONDO:0010961	PCSK1	P29120	3.4.21.93	R-HSA-264876 R-HSA-264876 Reactome Name: Insulin processing See in Reactome R-HSA-422085 R-HSA-422085 Reactome Name: Synthesis, secretion, and deacylation of Ghrelin See in Reactome R-HSA-381771 R-HSA-381771 Reactome Name: Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) See in Reactome R-HSA-400511 R-HSA-400511 Reactome Name: Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) See in Reactome R-HSA-209952 R-HSA-209952 Reactome Name: Peptide hormone biosynthesis See in Reactome	R-HSA-400508 R-HSA-400508 Reactome Name: Incretin synthesis, secretion, and inactivation See in Reactome R-HSA-2980736 R-HSA-2980736 Reactome Name: Peptide hormone metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome	Metabolism of proteins	R-HSA-265301 ( R-HSA-209952 ) R-HSA-265301 Reaction Name: Corticotropin cleavage from POMC See in Reactome R-HSA-381798 ( R-HSA-381771 ) R-HSA-381798 Reaction Name: PCSK1 hydrolyzes Proglucagon to Glucagon-like Peptide-1 See in Reactome R-HSA-400492 ( R-HSA-400511 ) R-HSA-400492 Reaction Name: PCSK1 hydrolyzes proGIP to GIP See in Reactome R-HSA-422021 ( R-HSA-422085 ) R-HSA-422021 Reaction Name: PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin See in Reactome R-HSA-9023196 ( R-HSA-264876 ) R-HSA-9023196 Reaction Name: PCSK1 cleaves proinsulin to yield Insulin(25-56) and Insulin(57-110) See in Reactome
MONDO:0013663	PLA2G7	Q13093	3.1.1.47	R-HSA-422085 R-HSA-422085 Reactome Name: Synthesis, secretion, and deacylation of Ghrelin See in Reactome	R-HSA-2980736 R-HSA-2980736 Reactome Name: Peptide hormone metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome	Metabolism of proteins	R-HSA-9023619 ( R-HSA-422085 ) R-HSA-9023619 Reaction Name: Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin See in Reactome
MONDO:0015270	BCHE	P06276	3.1.1.8	R-HSA-422085 R-HSA-422085 Reactome Name: Synthesis, secretion, and deacylation of Ghrelin See in Reactome R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-112311 R-HSA-112311 Reactome Name: Neurotransmitter clearance See in Reactome	R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-2980736 R-HSA-2980736 Reactome Name: Peptide hormone metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome	Metabolism of proteins Neuronal System Metabolism	R-HSA-372519 ( R-HSA-112311; R-HSA-1483191 ) R-HSA-372519 Reaction Name: AcCho is hydrolyzed to Cho and acetate by ACHE See in Reactome R-HSA-9023617 ( R-HSA-422085 ) R-HSA-9023617 Reaction Name: Butyrylcholinesterase hydrolyzes acyl Ghrelin See in Reactome