DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-389599)

Number of enzymes:	2
Number of disease:	3
Number of reactomes:	8
Number of reactions:	8

Search results (Reactome ID: R-HSA-389599)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009958	PHYH	O14832	1.14.11.18	R-HSA-9033500 R-HSA-9033500 Reactome Name: TYSND1 cleaves peroxisomal proteins See in Reactome R-HSA-9033241 R-HSA-9033241 Reactome Name: Peroxisomal protein import See in Reactome R-HSA-389599 R-HSA-389599 Reactome Name: Alpha-oxidation of phytanate See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-390918 R-HSA-390918 Reactome Name: Peroxisomal lipid metabolism See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism Protein localization	R-HSA-389639 ( R-HSA-389599 ) R-HSA-389639 Reaction Name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 See in Reactome R-HSA-9033232 ( R-HSA-9033241 ) R-HSA-9033232 Reaction Name: PEX7 binds cargo proteins containing PTS2 See in Reactome R-HSA-9033238 ( R-HSA-9033241 ) R-HSA-9033238 Reaction Name: PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) See in Reactome R-HSA-9033240 ( R-HSA-9033241 ) R-HSA-9033240 Reaction Name: PEX5L binds PEX7:Cargo protein See in Reactome R-HSA-9033490 ( R-HSA-9033241; R-HSA-9033500 ) R-HSA-9033490 Reaction Name: TYSND1 cleaves PHYH See in Reactome R-HSA-9033514 ( R-HSA-9033241 ) R-HSA-9033514 Reaction Name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix See in Reactome
MONDO:0010031	ALDH3A2	P51648	1.2.1.3 1.2.1.94	R-HSA-9603798 R-HSA-9603798 Reactome Name: Class I peroxisomal membrane protein import See in Reactome R-HSA-1660661 R-HSA-1660661 Reactome Name: Sphingolipid de novo biosynthesis See in Reactome R-HSA-9696270 R-HSA-9696270 Reactome Name: RND2 GTPase cycle See in Reactome R-HSA-9696273 R-HSA-9696273 Reactome Name: RND1 GTPase cycle See in Reactome R-HSA-9609523 R-HSA-9609523 Reactome Name: Insertion of tail-anchored proteins into the endoplasmic reticulum membrane See in Reactome R-HSA-389599 R-HSA-389599 Reactome Name: Alpha-oxidation of phytanate See in Reactome	R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-390918 R-HSA-390918 Reactome Name: Peroxisomal lipid metabolism See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Protein localization Metabolism Signal Transduction	R-HSA-9696266 ( R-HSA-9696270 ) R-HSA-9696266 Reaction Name: RND2 binds effectors See in Reactome R-HSA-9696271 ( R-HSA-9696273 ) R-HSA-9696271 Reaction Name: RND1 binds effectors See in Reactome
MONDO:0019200	PHYH	O14832	1.14.11.18	R-HSA-9033500 R-HSA-9033500 Reactome Name: TYSND1 cleaves peroxisomal proteins See in Reactome R-HSA-9033241 R-HSA-9033241 Reactome Name: Peroxisomal protein import See in Reactome R-HSA-389599 R-HSA-389599 Reactome Name: Alpha-oxidation of phytanate See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-390918 R-HSA-390918 Reactome Name: Peroxisomal lipid metabolism See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome	Metabolism Protein localization	R-HSA-389639 ( R-HSA-389599 ) R-HSA-389639 Reaction Name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 See in Reactome R-HSA-9033232 ( R-HSA-9033241 ) R-HSA-9033232 Reaction Name: PEX7 binds cargo proteins containing PTS2 See in Reactome R-HSA-9033238 ( R-HSA-9033241 ) R-HSA-9033238 Reaction Name: PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) See in Reactome R-HSA-9033240 ( R-HSA-9033241 ) R-HSA-9033240 Reaction Name: PEX5L binds PEX7:Cargo protein See in Reactome R-HSA-9033490 ( R-HSA-9033241; R-HSA-9033500 ) R-HSA-9033490 Reaction Name: TYSND1 cleaves PHYH See in Reactome R-HSA-9033514 ( R-HSA-9033241 ) R-HSA-9033514 Reaction Name: Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix See in Reactome