DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-389542)

Number of enzymes:	1
Number of disease:	4
Number of reactomes:	3
Number of reactions:	9

Search results (Reactome ID: R-HSA-389542)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008145	IDH1	O75874	1.1.1.42	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-9033241 R-HSA-9033241 Reactome Name: Peroxisomal protein import See in Reactome R-HSA-389542 R-HSA-389542 Reactome Name: NADPH regeneration See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome R-HSA-8978934 R-HSA-8978934 Reactome Name: Metabolism of cofactors See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Immune System Protein localization Metabolism	R-HSA-389540 ( R-HSA-389542 ) R-HSA-389540 Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ See in Reactome R-HSA-389550 ( R-HSA-389542 ) R-HSA-389550 Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ See in Reactome R-HSA-6798745 ( R-HSA-6798695 ) R-HSA-6798745 Reaction Name: Exocytosis of tertiary granule lumen proteins See in Reactome R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-9033233 ( R-HSA-9033241 ) R-HSA-9033233 Reaction Name: PEX5S See in Reactome R-HSA-9033233 ( R-HSA-9033241 ) R-HSA-9033233 Reaction Name: PEX5S,L binds cargo proteins containing PTS1 See in Reactome R-HSA-9033235 ( R-HSA-9033241 ) R-HSA-9033235 Reaction Name: Cargo of PEX5S See in Reactome R-HSA-9033235 ( R-HSA-9033241 ) R-HSA-9033235 Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix See in Reactome R-HSA-9033236 ( R-HSA-9033241 ) R-HSA-9033236 Reaction Name: PEX5S See in Reactome R-HSA-9033236 ( R-HSA-9033241 ) R-HSA-9033236 Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) See in Reactome R-HSA-9761844 () R-HSA-9761844 Reaction Name: NFE2L2-dependent IDH1 gene expression See in Reactome
MONDO:0013808	IDH1	O75874	1.1.1.42	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-9033241 R-HSA-9033241 Reactome Name: Peroxisomal protein import See in Reactome R-HSA-389542 R-HSA-389542 Reactome Name: NADPH regeneration See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome R-HSA-8978934 R-HSA-8978934 Reactome Name: Metabolism of cofactors See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Immune System Protein localization Metabolism	R-HSA-389540 ( R-HSA-389542 ) R-HSA-389540 Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ See in Reactome R-HSA-389550 ( R-HSA-389542 ) R-HSA-389550 Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ See in Reactome R-HSA-6798745 ( R-HSA-6798695 ) R-HSA-6798745 Reaction Name: Exocytosis of tertiary granule lumen proteins See in Reactome R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-9033233 ( R-HSA-9033241 ) R-HSA-9033233 Reaction Name: PEX5S See in Reactome R-HSA-9033233 ( R-HSA-9033241 ) R-HSA-9033233 Reaction Name: PEX5S,L binds cargo proteins containing PTS1 See in Reactome R-HSA-9033235 ( R-HSA-9033241 ) R-HSA-9033235 Reaction Name: Cargo of PEX5S See in Reactome R-HSA-9033235 ( R-HSA-9033241 ) R-HSA-9033235 Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix See in Reactome R-HSA-9033236 ( R-HSA-9033241 ) R-HSA-9033236 Reaction Name: PEX5S See in Reactome R-HSA-9033236 ( R-HSA-9033241 ) R-HSA-9033236 Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) See in Reactome R-HSA-9761844 () R-HSA-9761844 Reaction Name: NFE2L2-dependent IDH1 gene expression See in Reactome
MONDO:0013941	IDH1	O75874	1.1.1.42	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-9033241 R-HSA-9033241 Reactome Name: Peroxisomal protein import See in Reactome R-HSA-389542 R-HSA-389542 Reactome Name: NADPH regeneration See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome R-HSA-8978934 R-HSA-8978934 Reactome Name: Metabolism of cofactors See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Immune System Protein localization Metabolism	R-HSA-389540 ( R-HSA-389542 ) R-HSA-389540 Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ See in Reactome R-HSA-389550 ( R-HSA-389542 ) R-HSA-389550 Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ See in Reactome R-HSA-6798745 ( R-HSA-6798695 ) R-HSA-6798745 Reaction Name: Exocytosis of tertiary granule lumen proteins See in Reactome R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-9033233 ( R-HSA-9033241 ) R-HSA-9033233 Reaction Name: PEX5S See in Reactome R-HSA-9033233 ( R-HSA-9033241 ) R-HSA-9033233 Reaction Name: PEX5S,L binds cargo proteins containing PTS1 See in Reactome R-HSA-9033235 ( R-HSA-9033241 ) R-HSA-9033235 Reaction Name: Cargo of PEX5S See in Reactome R-HSA-9033235 ( R-HSA-9033241 ) R-HSA-9033235 Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix See in Reactome R-HSA-9033236 ( R-HSA-9033241 ) R-HSA-9033236 Reaction Name: PEX5S See in Reactome R-HSA-9033236 ( R-HSA-9033241 ) R-HSA-9033236 Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) See in Reactome R-HSA-9761844 () R-HSA-9761844 Reaction Name: NFE2L2-dependent IDH1 gene expression See in Reactome
MONDO:0024498	IDH1	O75874	1.1.1.42	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-9033241 R-HSA-9033241 Reactome Name: Peroxisomal protein import See in Reactome R-HSA-389542 R-HSA-389542 Reactome Name: NADPH regeneration See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome R-HSA-8978934 R-HSA-8978934 Reactome Name: Metabolism of cofactors See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Immune System Protein localization Metabolism	R-HSA-389540 ( R-HSA-389542 ) R-HSA-389540 Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ See in Reactome R-HSA-389550 ( R-HSA-389542 ) R-HSA-389550 Reaction Name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ See in Reactome R-HSA-6798745 ( R-HSA-6798695 ) R-HSA-6798745 Reaction Name: Exocytosis of tertiary granule lumen proteins See in Reactome R-HSA-6798748 ( R-HSA-6798695 ) R-HSA-6798748 Reaction Name: Exocytosis of secretory granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome R-HSA-9033233 ( R-HSA-9033241 ) R-HSA-9033233 Reaction Name: PEX5S See in Reactome R-HSA-9033233 ( R-HSA-9033241 ) R-HSA-9033233 Reaction Name: PEX5S,L binds cargo proteins containing PTS1 See in Reactome R-HSA-9033235 ( R-HSA-9033241 ) R-HSA-9033235 Reaction Name: Cargo of PEX5S See in Reactome R-HSA-9033235 ( R-HSA-9033241 ) R-HSA-9033235 Reaction Name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix See in Reactome R-HSA-9033236 ( R-HSA-9033241 ) R-HSA-9033236 Reaction Name: PEX5S See in Reactome R-HSA-9033236 ( R-HSA-9033241 ) R-HSA-9033236 Reaction Name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) See in Reactome R-HSA-9761844 () R-HSA-9761844 Reaction Name: NFE2L2-dependent IDH1 gene expression See in Reactome