DAR - Bologna Biocomputing Group

Search results (Reactome ID: R-HSA-381340)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0005012	CDK4	P11802	2.7.11.22	R-HSA-2559585 R-HSA-2559585 Reactome Name: Oncogene Induced Senescence See in Reactome R-HSA-2559580 R-HSA-2559580 Reactome Name: Oxidative Stress Induced Senescence See in Reactome R-HSA-2559582 R-HSA-2559582 Reactome Name: Senescence-Associated Secretory Phenotype (SASP) See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-912446 R-HSA-912446 Reactome Name: Meiotic recombination See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-8849470 R-HSA-8849470 Reactome Name: PTK6 Regulates Cell Cycle See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-75815 R-HSA-75815 Reactome Name: Ubiquitin-dependent degradation of Cyclin D See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-187577 R-HSA-187577 Reactome Name: SCF(Skp2)-mediated degradation of p27/p21 See in Reactome	R-HSA-8848021 R-HSA-8848021 Reactome Name: Signaling by PTK6 See in Reactome R-HSA-2559583 R-HSA-2559583 Reactome Name: Cellular Senescence See in Reactome R-HSA-9006927 R-HSA-9006927 Reactome Name: Signaling by Non-Receptor Tyrosine Kinases See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1474165 R-HSA-1474165 Reactome Name: Reproduction See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-69656 R-HSA-69656 Reactome Name: Cyclin A:Cdk2-associated events at S phase entry See in Reactome R-HSA-69206 R-HSA-69206 Reactome Name: G1/S Transition See in Reactome R-HSA-69202 R-HSA-69202 Reactome Name: Cyclin E associated events during G1/S transition See in Reactome R-HSA-69242 R-HSA-69242 Reactome Name: S Phase See in Reactome R-HSA-1500620 R-HSA-1500620 Reactome Name: Meiosis See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction	R-HSA-1226094 ( R-HSA-69231 ) R-HSA-1226094 Reaction Name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex See in Reactome R-HSA-1226095 ( R-HSA-69231 ) R-HSA-1226095 Reaction Name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex See in Reactome R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-182594 Reaction Name: Association of INK4 family proteins with CDK4/6 See in Reactome R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215385 Reaction Name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 See in Reactome R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-3215426 Reaction Name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 See in Reactome R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-5216234 Reaction Name: PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-5661117 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 See in Reactome R-HSA-69227 ( R-HSA-69231 ) R-HSA-69227 Reaction Name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-75820 ( R-HSA-75815 ) R-HSA-75820 Reaction Name: Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta See in Reactome R-HSA-75822 ( R-HSA-75815 ) R-HSA-75822 Reaction Name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm See in Reactome R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848414 Reaction Name: Activated PTK6 binds CDKN1B See in Reactome R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 Reaction Name: PTK6 phosphorylates CDKN1B See in Reactome R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941895 Reaction Name: Formation of CDK4/6:CCND complexes See in Reactome R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8941915 Reaction Name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes See in Reactome R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942607 Reaction Name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes See in Reactome R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942803 Reaction Name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus See in Reactome R-HSA-8942836 ( R-HSA-69231 ) R-HSA-8942836 Reaction Name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 See in Reactome R-HSA-9008412 ( R-HSA-212436; R-HSA-8878166 ) R-HSA-9008412 Reaction Name: CDK4 phosphorylates RUNX2 See in Reactome R-HSA-9018017 ( R-HSA-69231 ) R-HSA-9018017 Reaction Name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-912429 ( R-HSA-912446 ) R-HSA-912429 Reaction Name: Resolution of meiotic holliday junction See in Reactome R-HSA-912458 ( R-HSA-912446 ) R-HSA-912458 Reaction Name: Formation of meiotic heteroduplex See in Reactome R-HSA-912496 ( R-HSA-912446 ) R-HSA-912496 Reaction Name: Formation of meiotic holliday junction See in Reactome R-HSA-912503 ( R-HSA-912446 ) R-HSA-912503 Reaction Name: Formation of meiotic single-stranded DNA invasion complex See in Reactome R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9624112 Reaction Name: CEBPA binds CDK4 See in Reactome R-HSA-9754130 ( R-HSA-69231 ) R-HSA-9754130 Reaction Name: CDK4 inhibitors bind CDK4 See in Reactome
MONDO:0005061	CDK4	P11802	2.7.11.22	R-HSA-2559585 R-HSA-2559585 Reactome Name: Oncogene Induced Senescence See in Reactome R-HSA-2559580 R-HSA-2559580 Reactome Name: Oxidative Stress Induced Senescence See in Reactome R-HSA-2559582 R-HSA-2559582 Reactome Name: Senescence-Associated Secretory Phenotype (SASP) See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-912446 R-HSA-912446 Reactome Name: Meiotic recombination See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-8849470 R-HSA-8849470 Reactome Name: PTK6 Regulates Cell Cycle See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-75815 R-HSA-75815 Reactome Name: Ubiquitin-dependent degradation of Cyclin D See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-187577 R-HSA-187577 Reactome Name: SCF(Skp2)-mediated degradation of p27/p21 See in Reactome	R-HSA-8848021 R-HSA-8848021 Reactome Name: Signaling by PTK6 See in Reactome R-HSA-2559583 R-HSA-2559583 Reactome Name: Cellular Senescence See in Reactome R-HSA-9006927 R-HSA-9006927 Reactome Name: Signaling by Non-Receptor Tyrosine Kinases See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1474165 R-HSA-1474165 Reactome Name: Reproduction See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-69656 R-HSA-69656 Reactome Name: Cyclin A:Cdk2-associated events at S phase entry See in Reactome R-HSA-69206 R-HSA-69206 Reactome Name: G1/S Transition See in Reactome R-HSA-69202 R-HSA-69202 Reactome Name: Cyclin E associated events during G1/S transition See in Reactome R-HSA-69242 R-HSA-69242 Reactome Name: S Phase See in Reactome R-HSA-1500620 R-HSA-1500620 Reactome Name: Meiosis See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction	R-HSA-1226094 ( R-HSA-69231 ) R-HSA-1226094 Reaction Name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex See in Reactome R-HSA-1226095 ( R-HSA-69231 ) R-HSA-1226095 Reaction Name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex See in Reactome R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-182594 Reaction Name: Association of INK4 family proteins with CDK4/6 See in Reactome R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215385 Reaction Name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 See in Reactome R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-3215426 Reaction Name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 See in Reactome R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-5216234 Reaction Name: PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-5661117 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 See in Reactome R-HSA-69227 ( R-HSA-69231 ) R-HSA-69227 Reaction Name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-75820 ( R-HSA-75815 ) R-HSA-75820 Reaction Name: Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta See in Reactome R-HSA-75822 ( R-HSA-75815 ) R-HSA-75822 Reaction Name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm See in Reactome R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848414 Reaction Name: Activated PTK6 binds CDKN1B See in Reactome R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 Reaction Name: PTK6 phosphorylates CDKN1B See in Reactome R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941895 Reaction Name: Formation of CDK4/6:CCND complexes See in Reactome R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8941915 Reaction Name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes See in Reactome R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942607 Reaction Name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes See in Reactome R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942803 Reaction Name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus See in Reactome R-HSA-8942836 ( R-HSA-69231 ) R-HSA-8942836 Reaction Name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 See in Reactome R-HSA-9008412 ( R-HSA-212436; R-HSA-8878166 ) R-HSA-9008412 Reaction Name: CDK4 phosphorylates RUNX2 See in Reactome R-HSA-9018017 ( R-HSA-69231 ) R-HSA-9018017 Reaction Name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-912429 ( R-HSA-912446 ) R-HSA-912429 Reaction Name: Resolution of meiotic holliday junction See in Reactome R-HSA-912458 ( R-HSA-912446 ) R-HSA-912458 Reaction Name: Formation of meiotic heteroduplex See in Reactome R-HSA-912496 ( R-HSA-912446 ) R-HSA-912496 Reaction Name: Formation of meiotic holliday junction See in Reactome R-HSA-912503 ( R-HSA-912446 ) R-HSA-912503 Reaction Name: Formation of meiotic single-stranded DNA invasion complex See in Reactome R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9624112 Reaction Name: CEBPA binds CDK4 See in Reactome R-HSA-9754130 ( R-HSA-69231 ) R-HSA-9754130 Reaction Name: CDK4 inhibitors bind CDK4 See in Reactome
MONDO:0005097	EP300	Q09472	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-5689901 R-HSA-5689901 Reactome Name: Metalloprotease DUBs See in Reactome R-HSA-6804760 R-HSA-6804760 Reactome Name: Regulation of TP53 Activity through Methylation See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-6782135 R-HSA-6782135 Reactome Name: Dual incision in TC-NER See in Reactome R-HSA-6782210 R-HSA-6782210 Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-6804114 R-HSA-6804114 Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-6781827 R-HSA-6781827 Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER) See in Reactome R-HSA-156711 R-HSA-156711 Reactome Name: Polo-like kinase mediated events See in Reactome R-HSA-5250924 R-HSA-5250924 Reactome Name: B-WICH complex positively regulates rRNA expression See in Reactome R-HSA-6781823 R-HSA-6781823 Reactome Name: Formation of TC-NER Pre-Incision Complex See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-9701898 R-HSA-9701898 Reactome Name: STAT3 nuclear events downstream of ALK signaling See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8936459 R-HSA-8936459 Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2197563 R-HSA-2197563 Reactome Name: NOTCH2 intracellular domain regulates transcription See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8951936 R-HSA-8951936 Reactome Name: RUNX3 regulates p14-ARF See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-6811555 R-HSA-6811555 Reactome Name: PI5P Regulates TP53 Acetylation See in Reactome R-HSA-6804758 R-HSA-6804758 Reactome Name: Regulation of TP53 Activity through Acetylation See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-6791312 R-HSA-6791312 Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-5696398 R-HSA-5696398 Reactome Name: Nucleotide Excision Repair See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-1980145 R-HSA-1980145 Reactome Name: Signaling by NOTCH2 See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-5250913 R-HSA-5250913 Reactome Name: Positive epigenetic regulation of rRNA expression See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome	Circadian Clock Immune System Cell Cycle Developmental Biology Metabolism Gene expression (Transcription) DNA Repair Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-6782069 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782069 Reaction Name: UVSSA:USP7 deubiquitinates ERCC6 See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome R-HSA-9011981 ( R-HSA-9018519 ) R-HSA-9011981 Reaction Name: EP300 is recruited to MYC and BCL2 genes See in Reactome R-HSA-8878050 ( R-HSA-8939243 ) R-HSA-8878050 Reaction Name: HIPK2 phosphorylates RUNX1 and EP300 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-8952101 ( R-HSA-8951936 ) R-HSA-8952101 Reaction Name: p14-ARF transcription is stimulated by RUNX proteins See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9038163 ( R-HSA-9018519 ) R-HSA-9038163 Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-6782211 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782211 Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-9613451 ( R-HSA-9031628 ) R-HSA-9613451 Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes See in Reactome R-HSA-8936621 ( R-HSA-8936459 ) R-HSA-8936621 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter See in Reactome R-HSA-5628871 ( R-HSA-6804758 ) R-HSA-5628871 Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9620723 ( R-HSA-9031628 ) R-HSA-9620723 Reaction Name: VGF gene expression See in Reactome R-HSA-5250938 ( R-HSA-5250924 ) R-HSA-5250938 Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 See in Reactome R-HSA-6782204 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782204 Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER See in Reactome R-HSA-5617867 ( R-HSA-5617472 ) R-HSA-5617867 Reaction Name: HOXB4 gene is transcribed See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-9023884 ( R-HSA-9018519 ) R-HSA-9023884 Reaction Name: NCOA1 recruits EP300 to TGFA promoter See in Reactome R-HSA-8937050 ( R-HSA-8936459 ) R-HSA-8937050 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter See in Reactome R-HSA-8952081 ( R-HSA-8951936 ) R-HSA-8952081 Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus See in Reactome R-HSA-3662335 ( R-HSA-3214847 ) R-HSA-3662335 Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4 See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-6804379 ( R-HSA-6804760 ) R-HSA-6804379 Reaction Name: PRMT5 binds TTC5 See in Reactome R-HSA-4088162 ( R-HSA-156711 ) R-HSA-4088162 Reaction Name: FOXM1 binds CDC25A promoter See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-9023846 ( R-HSA-9018519 ) R-HSA-9023846 Reaction Name: Estrogen-responsive CTSD expression See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-9008315 ( R-HSA-9018519 ) R-HSA-9008315 Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen See in Reactome R-HSA-8936628 ( R-HSA-8936459 ) R-HSA-8936628 Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9023860 ( R-HSA-9018519 ) R-HSA-9023860 Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-8936481 ( R-HSA-8936459 ) R-HSA-8936481 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter See in Reactome R-HSA-5663264 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663264 Reaction Name: RORA, EP300 bind CPT1A gene See in Reactome R-HSA-6805650 ( R-HSA-6804758 ) R-HSA-6805650 Reaction Name: MTA2-NuRD complex deacetylates TP53 See in Reactome R-HSA-5617452 ( R-HSA-5617472 ) R-HSA-5617452 Reaction Name: Retinoic acid activates HOXB1 chromatin See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-9613460 ( R-HSA-9031628 ) R-HSA-9613460 Reaction Name: ID1 and ID3 gene expression See in Reactome R-HSA-9620717 ( R-HSA-9031628 ) R-HSA-9620717 Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter See in Reactome R-HSA-8951951 ( R-HSA-8951936 ) R-HSA-8951951 Reaction Name: RUNX3 binds EP300 See in Reactome R-HSA-9029561 ( R-HSA-9029569 ) R-HSA-9029561 Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-9617064 ( R-HSA-9616222 ) R-HSA-9617064 Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene See in Reactome R-HSA-9008285 ( R-HSA-9018519 ) R-HSA-9008285 Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-9701531 ( R-HSA-9701898 ) R-HSA-9701531 Reaction Name: p-Y705,S727 STAT3 is acetylated See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-8937097 ( R-HSA-8936459 ) R-HSA-8937097 Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-8936616 ( R-HSA-8936459 ) R-HSA-8936616 Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene See in Reactome R-HSA-5663246 ( R-HSA-400253 ) R-HSA-5663246 Reaction Name: RORA, EP300 bind NPAS2 gene See in Reactome R-HSA-6804229 ( R-HSA-6804760 ) R-HSA-6804229 Reaction Name: JMY, TTC5 and EP300 bind See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-8878056 ( R-HSA-8939243 ) R-HSA-8878056 Reaction Name: RUNX1:CBFB binds EP300 See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-6782004 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782004 Reaction Name: Assembly of the pre-incision complex in TC-NER See in Reactome R-HSA-5250930 ( R-HSA-5250924 ) R-HSA-5250930 Reaction Name: B-WICH recruits histone acetyltransferases See in Reactome R-HSA-8937016 ( R-HSA-8936459 ) R-HSA-8937016 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter See in Reactome R-HSA-400342 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-400342 Reaction Name: Expression of ARNTL (BMAL1) See in Reactome R-HSA-6782138 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782138 Reaction Name: ERCC5 and RPA bind TC-NER site See in Reactome R-HSA-5617859 ( R-HSA-5617472 ) R-HSA-5617859 Reaction Name: Retinoic acid activates HOXB4 chromatin See in Reactome R-HSA-8952058 ( R-HSA-8951936 ) R-HSA-8952058 Reaction Name: CCND1 binds RUNX3 and displaces EP300 See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-9620515 ( R-HSA-9617629 ) R-HSA-9620515 Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-5693644 ( R-HSA-5617472 ) R-HSA-5693644 Reaction Name: HOXB1 maintains activation of HOXB1 chromatin See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-5617862 ( R-HSA-5617472 ) R-HSA-5617862 Reaction Name: Retinoic acid activates HOXA4 chromatin See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-8935731 ( R-HSA-8936459 ) R-HSA-8935731 Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-6782208 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782208 Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER See in Reactome R-HSA-5663293 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663293 Reaction Name: RORA, EP300 bind SREBF1 gene See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-549475 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-549475 Reaction Name: Expression of NR1D1 (REV-ERBA) See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-6782227 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782227 Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER See in Reactome R-HSA-6811508 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811508 Reaction Name: ING2-bound EP300 acetylates TP53 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-8951977 ( R-HSA-8951936 ) R-HSA-8951977 Reaction Name: Acetylated RUNX3 binds to BRD2 See in Reactome R-HSA-9023840 ( R-HSA-9018519 ) R-HSA-9023840 Reaction Name: HATs and coactivators are recruited to the CTSD gene See in Reactome R-HSA-6811479 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811479 Reaction Name: ING2 recruits EP300 to TP53 See in Reactome R-HSA-5617877 ( R-HSA-5617472 ) R-HSA-5617877 Reaction Name: HOXA4 gene is transcribed See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-6804383 ( R-HSA-6804760 ) R-HSA-6804383 Reaction Name: PRMT5 methylates TP53 See in Reactome R-HSA-6782234 ( R-HSA-6781827 ) R-HSA-6782234 Reaction Name: Recovery of RNA synthesis after TC-NER See in Reactome R-HSA-9011975 ( R-HSA-9018519 ) R-HSA-9011975 Reaction Name: Estrogen-responsive MYC gene expression See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-2976551 ( R-HSA-2197563 ) R-HSA-2976551 Reaction Name: NOTCH2 stimulates GZMB transcription See in Reactome R-HSA-1368081 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-1368081 Reaction Name: Expression of SREBF1 (SREBP1) See in Reactome R-HSA-5617431 ( R-HSA-5617472 ) R-HSA-5617431 Reaction Name: Retinoic acid activates HOXA1 chromatin See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-3215152 ( R-HSA-6804114 ) R-HSA-3215152 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter See in Reactome R-HSA-4088152 ( R-HSA-156711 ) R-HSA-4088152 Reaction Name: FOXM1 stimulates CDC25A transcription See in Reactome R-HSA-9009371 ( R-HSA-9018519 ) R-HSA-9009371 Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter See in Reactome R-HSA-9023859 ( R-HSA-9018519 ) R-HSA-9023859 Reaction Name: Estrogen-responsive TFF1 gene expression See in Reactome R-HSA-1368087 ( R-HSA-400253 ) R-HSA-1368087 Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-3899291 ( R-HSA-3899300 ) R-HSA-3899291 Reaction Name: SUMOylation of EP300 with SUMO1 See in Reactome R-HSA-9634433 ( R-HSA-9616222 ) R-HSA-9634433 Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid See in Reactome R-HSA-9605057 ( R-HSA-9029569 ) R-HSA-9605057 Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 See in Reactome R-HSA-5617471 ( R-HSA-5617472 ) R-HSA-5617471 Reaction Name: HOXA1 gene is transcribed See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-5691381 ( R-HSA-5689901 ) R-HSA-5691381 Reaction Name: MYSM1 deubiquitinates Histone H2A See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9018499 ( R-HSA-9018519 ) R-HSA-9018499 Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-6782131 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782131 Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-8935740 ( R-HSA-8936459 ) R-HSA-8935740 Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene See in Reactome R-HSA-9009378 ( R-HSA-9018519 ) R-HSA-9009378 Reaction Name: Estrogen-responsive CCND1 gene expression See in Reactome R-HSA-8952419 ( R-HSA-8941858 ) R-HSA-8952419 Reaction Name: SMURFs ubiquitinate RUNX3 See in Reactome R-HSA-6782224 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782224 Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER See in Reactome R-HSA-8936979 ( R-HSA-8936459 ) R-HSA-8936979 Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-3215144 ( R-HSA-6804114 ) R-HSA-3215144 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription See in Reactome R-HSA-8951966 ( R-HSA-8951936 ) R-HSA-8951966 Reaction Name: EP300 acetylates RUNX3 See in Reactome R-HSA-9008271 ( R-HSA-9018519 ) R-HSA-9008271 Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter See in Reactome R-HSA-9011941 ( R-HSA-9018519 ) R-HSA-9011941 Reaction Name: Estrogen-responsive BCL2 gene expression See in Reactome R-HSA-2976563 ( R-HSA-2197563 ) R-HSA-2976563 Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter See in Reactome R-HSA-5663273 ( R-HSA-400253 ) R-HSA-5663273 Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-6782141 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782141 Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-8937037 ( R-HSA-8936459 ) R-HSA-8937037 Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-9617735 ( R-HSA-9617629 ) R-HSA-9617735 Reaction Name: TXN disrupts FOXO4 complex with EP300 See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-9018497 ( R-HSA-9018519 ) R-HSA-9018497 Reaction Name: Estrogen-responsive TFF3 gene expression See in Reactome R-HSA-8936995 ( R-HSA-8936459 ) R-HSA-8936995 Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9684118 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-9684118 Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-6804242 ( R-HSA-6804760 ) R-HSA-6804242 Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5 See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-3222093 ( R-HSA-6804758 ) R-HSA-3222093 Reaction Name: BRD7 binds TP53 and EP300 See in Reactome
MONDO:0005148	SLC2A4	P14672	-	R-HSA-189200 R-HSA-189200 Reactome Name: Cellular hexose transport See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-1445148 R-HSA-1445148 Reactome Name: Translocation of SLC2A4 (GLUT4) to the plasma membrane See in Reactome	R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-425407 R-HSA-425407 Reactome Name: SLC-mediated transmembrane transport See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Developmental Biology Transport of small molecules Vesicle-mediated transport	R-HSA-1183032 ( R-HSA-381340 ) R-HSA-1183032 Reaction Name: Expression of GLUT4 See in Reactome R-HSA-1449574 ( R-HSA-1445148 ) R-HSA-1449574 Reaction Name: SLC2A4 (GLUT4) vesicle fuses with the plasma membrane See in Reactome R-HSA-8981570 ( R-HSA-189200 ) R-HSA-8981570 Reaction Name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol See in Reactome
MONDO:0005575	EP300	Q09472	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-5689901 R-HSA-5689901 Reactome Name: Metalloprotease DUBs See in Reactome R-HSA-6804760 R-HSA-6804760 Reactome Name: Regulation of TP53 Activity through Methylation See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-6782135 R-HSA-6782135 Reactome Name: Dual incision in TC-NER See in Reactome R-HSA-6782210 R-HSA-6782210 Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-6804114 R-HSA-6804114 Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-6781827 R-HSA-6781827 Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER) See in Reactome R-HSA-156711 R-HSA-156711 Reactome Name: Polo-like kinase mediated events See in Reactome R-HSA-5250924 R-HSA-5250924 Reactome Name: B-WICH complex positively regulates rRNA expression See in Reactome R-HSA-6781823 R-HSA-6781823 Reactome Name: Formation of TC-NER Pre-Incision Complex See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-9701898 R-HSA-9701898 Reactome Name: STAT3 nuclear events downstream of ALK signaling See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8936459 R-HSA-8936459 Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2197563 R-HSA-2197563 Reactome Name: NOTCH2 intracellular domain regulates transcription See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8951936 R-HSA-8951936 Reactome Name: RUNX3 regulates p14-ARF See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-6811555 R-HSA-6811555 Reactome Name: PI5P Regulates TP53 Acetylation See in Reactome R-HSA-6804758 R-HSA-6804758 Reactome Name: Regulation of TP53 Activity through Acetylation See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-6791312 R-HSA-6791312 Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-5696398 R-HSA-5696398 Reactome Name: Nucleotide Excision Repair See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-1980145 R-HSA-1980145 Reactome Name: Signaling by NOTCH2 See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-5250913 R-HSA-5250913 Reactome Name: Positive epigenetic regulation of rRNA expression See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome	Circadian Clock Immune System Cell Cycle Developmental Biology Metabolism Gene expression (Transcription) DNA Repair Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-6782069 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782069 Reaction Name: UVSSA:USP7 deubiquitinates ERCC6 See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome R-HSA-9011981 ( R-HSA-9018519 ) R-HSA-9011981 Reaction Name: EP300 is recruited to MYC and BCL2 genes See in Reactome R-HSA-8878050 ( R-HSA-8939243 ) R-HSA-8878050 Reaction Name: HIPK2 phosphorylates RUNX1 and EP300 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-8952101 ( R-HSA-8951936 ) R-HSA-8952101 Reaction Name: p14-ARF transcription is stimulated by RUNX proteins See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9038163 ( R-HSA-9018519 ) R-HSA-9038163 Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-6782211 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782211 Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-9613451 ( R-HSA-9031628 ) R-HSA-9613451 Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes See in Reactome R-HSA-8936621 ( R-HSA-8936459 ) R-HSA-8936621 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter See in Reactome R-HSA-5628871 ( R-HSA-6804758 ) R-HSA-5628871 Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9620723 ( R-HSA-9031628 ) R-HSA-9620723 Reaction Name: VGF gene expression See in Reactome R-HSA-5250938 ( R-HSA-5250924 ) R-HSA-5250938 Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 See in Reactome R-HSA-6782204 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782204 Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER See in Reactome R-HSA-5617867 ( R-HSA-5617472 ) R-HSA-5617867 Reaction Name: HOXB4 gene is transcribed See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-9023884 ( R-HSA-9018519 ) R-HSA-9023884 Reaction Name: NCOA1 recruits EP300 to TGFA promoter See in Reactome R-HSA-8937050 ( R-HSA-8936459 ) R-HSA-8937050 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter See in Reactome R-HSA-8952081 ( R-HSA-8951936 ) R-HSA-8952081 Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus See in Reactome R-HSA-3662335 ( R-HSA-3214847 ) R-HSA-3662335 Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4 See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-6804379 ( R-HSA-6804760 ) R-HSA-6804379 Reaction Name: PRMT5 binds TTC5 See in Reactome R-HSA-4088162 ( R-HSA-156711 ) R-HSA-4088162 Reaction Name: FOXM1 binds CDC25A promoter See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-9023846 ( R-HSA-9018519 ) R-HSA-9023846 Reaction Name: Estrogen-responsive CTSD expression See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-9008315 ( R-HSA-9018519 ) R-HSA-9008315 Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen See in Reactome R-HSA-8936628 ( R-HSA-8936459 ) R-HSA-8936628 Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9023860 ( R-HSA-9018519 ) R-HSA-9023860 Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-8936481 ( R-HSA-8936459 ) R-HSA-8936481 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter See in Reactome R-HSA-5663264 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663264 Reaction Name: RORA, EP300 bind CPT1A gene See in Reactome R-HSA-6805650 ( R-HSA-6804758 ) R-HSA-6805650 Reaction Name: MTA2-NuRD complex deacetylates TP53 See in Reactome R-HSA-5617452 ( R-HSA-5617472 ) R-HSA-5617452 Reaction Name: Retinoic acid activates HOXB1 chromatin See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-9613460 ( R-HSA-9031628 ) R-HSA-9613460 Reaction Name: ID1 and ID3 gene expression See in Reactome R-HSA-9620717 ( R-HSA-9031628 ) R-HSA-9620717 Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter See in Reactome R-HSA-8951951 ( R-HSA-8951936 ) R-HSA-8951951 Reaction Name: RUNX3 binds EP300 See in Reactome R-HSA-9029561 ( R-HSA-9029569 ) R-HSA-9029561 Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-9617064 ( R-HSA-9616222 ) R-HSA-9617064 Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene See in Reactome R-HSA-9008285 ( R-HSA-9018519 ) R-HSA-9008285 Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-9701531 ( R-HSA-9701898 ) R-HSA-9701531 Reaction Name: p-Y705,S727 STAT3 is acetylated See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-8937097 ( R-HSA-8936459 ) R-HSA-8937097 Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-8936616 ( R-HSA-8936459 ) R-HSA-8936616 Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene See in Reactome R-HSA-5663246 ( R-HSA-400253 ) R-HSA-5663246 Reaction Name: RORA, EP300 bind NPAS2 gene See in Reactome R-HSA-6804229 ( R-HSA-6804760 ) R-HSA-6804229 Reaction Name: JMY, TTC5 and EP300 bind See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-8878056 ( R-HSA-8939243 ) R-HSA-8878056 Reaction Name: RUNX1:CBFB binds EP300 See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-6782004 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782004 Reaction Name: Assembly of the pre-incision complex in TC-NER See in Reactome R-HSA-5250930 ( R-HSA-5250924 ) R-HSA-5250930 Reaction Name: B-WICH recruits histone acetyltransferases See in Reactome R-HSA-8937016 ( R-HSA-8936459 ) R-HSA-8937016 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter See in Reactome R-HSA-400342 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-400342 Reaction Name: Expression of ARNTL (BMAL1) See in Reactome R-HSA-6782138 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782138 Reaction Name: ERCC5 and RPA bind TC-NER site See in Reactome R-HSA-5617859 ( R-HSA-5617472 ) R-HSA-5617859 Reaction Name: Retinoic acid activates HOXB4 chromatin See in Reactome R-HSA-8952058 ( R-HSA-8951936 ) R-HSA-8952058 Reaction Name: CCND1 binds RUNX3 and displaces EP300 See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-9620515 ( R-HSA-9617629 ) R-HSA-9620515 Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-5693644 ( R-HSA-5617472 ) R-HSA-5693644 Reaction Name: HOXB1 maintains activation of HOXB1 chromatin See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-5617862 ( R-HSA-5617472 ) R-HSA-5617862 Reaction Name: Retinoic acid activates HOXA4 chromatin See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-8935731 ( R-HSA-8936459 ) R-HSA-8935731 Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-6782208 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782208 Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER See in Reactome R-HSA-5663293 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663293 Reaction Name: RORA, EP300 bind SREBF1 gene See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-549475 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-549475 Reaction Name: Expression of NR1D1 (REV-ERBA) See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-6782227 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782227 Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER See in Reactome R-HSA-6811508 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811508 Reaction Name: ING2-bound EP300 acetylates TP53 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-8951977 ( R-HSA-8951936 ) R-HSA-8951977 Reaction Name: Acetylated RUNX3 binds to BRD2 See in Reactome R-HSA-9023840 ( R-HSA-9018519 ) R-HSA-9023840 Reaction Name: HATs and coactivators are recruited to the CTSD gene See in Reactome R-HSA-6811479 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811479 Reaction Name: ING2 recruits EP300 to TP53 See in Reactome R-HSA-5617877 ( R-HSA-5617472 ) R-HSA-5617877 Reaction Name: HOXA4 gene is transcribed See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-6804383 ( R-HSA-6804760 ) R-HSA-6804383 Reaction Name: PRMT5 methylates TP53 See in Reactome R-HSA-6782234 ( R-HSA-6781827 ) R-HSA-6782234 Reaction Name: Recovery of RNA synthesis after TC-NER See in Reactome R-HSA-9011975 ( R-HSA-9018519 ) R-HSA-9011975 Reaction Name: Estrogen-responsive MYC gene expression See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-2976551 ( R-HSA-2197563 ) R-HSA-2976551 Reaction Name: NOTCH2 stimulates GZMB transcription See in Reactome R-HSA-1368081 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-1368081 Reaction Name: Expression of SREBF1 (SREBP1) See in Reactome R-HSA-5617431 ( R-HSA-5617472 ) R-HSA-5617431 Reaction Name: Retinoic acid activates HOXA1 chromatin See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-3215152 ( R-HSA-6804114 ) R-HSA-3215152 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter See in Reactome R-HSA-4088152 ( R-HSA-156711 ) R-HSA-4088152 Reaction Name: FOXM1 stimulates CDC25A transcription See in Reactome R-HSA-9009371 ( R-HSA-9018519 ) R-HSA-9009371 Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter See in Reactome R-HSA-9023859 ( R-HSA-9018519 ) R-HSA-9023859 Reaction Name: Estrogen-responsive TFF1 gene expression See in Reactome R-HSA-1368087 ( R-HSA-400253 ) R-HSA-1368087 Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-3899291 ( R-HSA-3899300 ) R-HSA-3899291 Reaction Name: SUMOylation of EP300 with SUMO1 See in Reactome R-HSA-9634433 ( R-HSA-9616222 ) R-HSA-9634433 Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid See in Reactome R-HSA-9605057 ( R-HSA-9029569 ) R-HSA-9605057 Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 See in Reactome R-HSA-5617471 ( R-HSA-5617472 ) R-HSA-5617471 Reaction Name: HOXA1 gene is transcribed See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-5691381 ( R-HSA-5689901 ) R-HSA-5691381 Reaction Name: MYSM1 deubiquitinates Histone H2A See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9018499 ( R-HSA-9018519 ) R-HSA-9018499 Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-6782131 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782131 Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-8935740 ( R-HSA-8936459 ) R-HSA-8935740 Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene See in Reactome R-HSA-9009378 ( R-HSA-9018519 ) R-HSA-9009378 Reaction Name: Estrogen-responsive CCND1 gene expression See in Reactome R-HSA-8952419 ( R-HSA-8941858 ) R-HSA-8952419 Reaction Name: SMURFs ubiquitinate RUNX3 See in Reactome R-HSA-6782224 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782224 Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER See in Reactome R-HSA-8936979 ( R-HSA-8936459 ) R-HSA-8936979 Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-3215144 ( R-HSA-6804114 ) R-HSA-3215144 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription See in Reactome R-HSA-8951966 ( R-HSA-8951936 ) R-HSA-8951966 Reaction Name: EP300 acetylates RUNX3 See in Reactome R-HSA-9008271 ( R-HSA-9018519 ) R-HSA-9008271 Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter See in Reactome R-HSA-9011941 ( R-HSA-9018519 ) R-HSA-9011941 Reaction Name: Estrogen-responsive BCL2 gene expression See in Reactome R-HSA-2976563 ( R-HSA-2197563 ) R-HSA-2976563 Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter See in Reactome R-HSA-5663273 ( R-HSA-400253 ) R-HSA-5663273 Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-6782141 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782141 Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-8937037 ( R-HSA-8936459 ) R-HSA-8937037 Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-9617735 ( R-HSA-9617629 ) R-HSA-9617735 Reaction Name: TXN disrupts FOXO4 complex with EP300 See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-9018497 ( R-HSA-9018519 ) R-HSA-9018497 Reaction Name: Estrogen-responsive TFF3 gene expression See in Reactome R-HSA-8936995 ( R-HSA-8936459 ) R-HSA-8936995 Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9684118 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-9684118 Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-6804242 ( R-HSA-6804760 ) R-HSA-6804242 Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5 See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-3222093 ( R-HSA-6804758 ) R-HSA-3222093 Reaction Name: BRD7 binds TP53 and EP300 See in Reactome
MONDO:0005611	EP300	Q09472	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-5689901 R-HSA-5689901 Reactome Name: Metalloprotease DUBs See in Reactome R-HSA-6804760 R-HSA-6804760 Reactome Name: Regulation of TP53 Activity through Methylation See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-6782135 R-HSA-6782135 Reactome Name: Dual incision in TC-NER See in Reactome R-HSA-6782210 R-HSA-6782210 Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-6804114 R-HSA-6804114 Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-6781827 R-HSA-6781827 Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER) See in Reactome R-HSA-156711 R-HSA-156711 Reactome Name: Polo-like kinase mediated events See in Reactome R-HSA-5250924 R-HSA-5250924 Reactome Name: B-WICH complex positively regulates rRNA expression See in Reactome R-HSA-6781823 R-HSA-6781823 Reactome Name: Formation of TC-NER Pre-Incision Complex See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-9701898 R-HSA-9701898 Reactome Name: STAT3 nuclear events downstream of ALK signaling See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8936459 R-HSA-8936459 Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2197563 R-HSA-2197563 Reactome Name: NOTCH2 intracellular domain regulates transcription See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8951936 R-HSA-8951936 Reactome Name: RUNX3 regulates p14-ARF See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-6811555 R-HSA-6811555 Reactome Name: PI5P Regulates TP53 Acetylation See in Reactome R-HSA-6804758 R-HSA-6804758 Reactome Name: Regulation of TP53 Activity through Acetylation See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-6791312 R-HSA-6791312 Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-5696398 R-HSA-5696398 Reactome Name: Nucleotide Excision Repair See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-1980145 R-HSA-1980145 Reactome Name: Signaling by NOTCH2 See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-5250913 R-HSA-5250913 Reactome Name: Positive epigenetic regulation of rRNA expression See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome	Circadian Clock Immune System Cell Cycle Developmental Biology Metabolism Gene expression (Transcription) DNA Repair Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-6782069 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782069 Reaction Name: UVSSA:USP7 deubiquitinates ERCC6 See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome R-HSA-9011981 ( R-HSA-9018519 ) R-HSA-9011981 Reaction Name: EP300 is recruited to MYC and BCL2 genes See in Reactome R-HSA-8878050 ( R-HSA-8939243 ) R-HSA-8878050 Reaction Name: HIPK2 phosphorylates RUNX1 and EP300 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-8952101 ( R-HSA-8951936 ) R-HSA-8952101 Reaction Name: p14-ARF transcription is stimulated by RUNX proteins See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9038163 ( R-HSA-9018519 ) R-HSA-9038163 Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-6782211 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782211 Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-9613451 ( R-HSA-9031628 ) R-HSA-9613451 Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes See in Reactome R-HSA-8936621 ( R-HSA-8936459 ) R-HSA-8936621 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter See in Reactome R-HSA-5628871 ( R-HSA-6804758 ) R-HSA-5628871 Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9620723 ( R-HSA-9031628 ) R-HSA-9620723 Reaction Name: VGF gene expression See in Reactome R-HSA-5250938 ( R-HSA-5250924 ) R-HSA-5250938 Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 See in Reactome R-HSA-6782204 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782204 Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER See in Reactome R-HSA-5617867 ( R-HSA-5617472 ) R-HSA-5617867 Reaction Name: HOXB4 gene is transcribed See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-9023884 ( R-HSA-9018519 ) R-HSA-9023884 Reaction Name: NCOA1 recruits EP300 to TGFA promoter See in Reactome R-HSA-8937050 ( R-HSA-8936459 ) R-HSA-8937050 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter See in Reactome R-HSA-8952081 ( R-HSA-8951936 ) R-HSA-8952081 Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus See in Reactome R-HSA-3662335 ( R-HSA-3214847 ) R-HSA-3662335 Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4 See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-6804379 ( R-HSA-6804760 ) R-HSA-6804379 Reaction Name: PRMT5 binds TTC5 See in Reactome R-HSA-4088162 ( R-HSA-156711 ) R-HSA-4088162 Reaction Name: FOXM1 binds CDC25A promoter See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-9023846 ( R-HSA-9018519 ) R-HSA-9023846 Reaction Name: Estrogen-responsive CTSD expression See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-9008315 ( R-HSA-9018519 ) R-HSA-9008315 Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen See in Reactome R-HSA-8936628 ( R-HSA-8936459 ) R-HSA-8936628 Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9023860 ( R-HSA-9018519 ) R-HSA-9023860 Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-8936481 ( R-HSA-8936459 ) R-HSA-8936481 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter See in Reactome R-HSA-5663264 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663264 Reaction Name: RORA, EP300 bind CPT1A gene See in Reactome R-HSA-6805650 ( R-HSA-6804758 ) R-HSA-6805650 Reaction Name: MTA2-NuRD complex deacetylates TP53 See in Reactome R-HSA-5617452 ( R-HSA-5617472 ) R-HSA-5617452 Reaction Name: Retinoic acid activates HOXB1 chromatin See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-9613460 ( R-HSA-9031628 ) R-HSA-9613460 Reaction Name: ID1 and ID3 gene expression See in Reactome R-HSA-9620717 ( R-HSA-9031628 ) R-HSA-9620717 Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter See in Reactome R-HSA-8951951 ( R-HSA-8951936 ) R-HSA-8951951 Reaction Name: RUNX3 binds EP300 See in Reactome R-HSA-9029561 ( R-HSA-9029569 ) R-HSA-9029561 Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-9617064 ( R-HSA-9616222 ) R-HSA-9617064 Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene See in Reactome R-HSA-9008285 ( R-HSA-9018519 ) R-HSA-9008285 Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-9701531 ( R-HSA-9701898 ) R-HSA-9701531 Reaction Name: p-Y705,S727 STAT3 is acetylated See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-8937097 ( R-HSA-8936459 ) R-HSA-8937097 Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-8936616 ( R-HSA-8936459 ) R-HSA-8936616 Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene See in Reactome R-HSA-5663246 ( R-HSA-400253 ) R-HSA-5663246 Reaction Name: RORA, EP300 bind NPAS2 gene See in Reactome R-HSA-6804229 ( R-HSA-6804760 ) R-HSA-6804229 Reaction Name: JMY, TTC5 and EP300 bind See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-8878056 ( R-HSA-8939243 ) R-HSA-8878056 Reaction Name: RUNX1:CBFB binds EP300 See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-6782004 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782004 Reaction Name: Assembly of the pre-incision complex in TC-NER See in Reactome R-HSA-5250930 ( R-HSA-5250924 ) R-HSA-5250930 Reaction Name: B-WICH recruits histone acetyltransferases See in Reactome R-HSA-8937016 ( R-HSA-8936459 ) R-HSA-8937016 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter See in Reactome R-HSA-400342 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-400342 Reaction Name: Expression of ARNTL (BMAL1) See in Reactome R-HSA-6782138 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782138 Reaction Name: ERCC5 and RPA bind TC-NER site See in Reactome R-HSA-5617859 ( R-HSA-5617472 ) R-HSA-5617859 Reaction Name: Retinoic acid activates HOXB4 chromatin See in Reactome R-HSA-8952058 ( R-HSA-8951936 ) R-HSA-8952058 Reaction Name: CCND1 binds RUNX3 and displaces EP300 See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-9620515 ( R-HSA-9617629 ) R-HSA-9620515 Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-5693644 ( R-HSA-5617472 ) R-HSA-5693644 Reaction Name: HOXB1 maintains activation of HOXB1 chromatin See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-5617862 ( R-HSA-5617472 ) R-HSA-5617862 Reaction Name: Retinoic acid activates HOXA4 chromatin See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-8935731 ( R-HSA-8936459 ) R-HSA-8935731 Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-6782208 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782208 Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER See in Reactome R-HSA-5663293 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663293 Reaction Name: RORA, EP300 bind SREBF1 gene See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-549475 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-549475 Reaction Name: Expression of NR1D1 (REV-ERBA) See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-6782227 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782227 Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER See in Reactome R-HSA-6811508 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811508 Reaction Name: ING2-bound EP300 acetylates TP53 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-8951977 ( R-HSA-8951936 ) R-HSA-8951977 Reaction Name: Acetylated RUNX3 binds to BRD2 See in Reactome R-HSA-9023840 ( R-HSA-9018519 ) R-HSA-9023840 Reaction Name: HATs and coactivators are recruited to the CTSD gene See in Reactome R-HSA-6811479 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811479 Reaction Name: ING2 recruits EP300 to TP53 See in Reactome R-HSA-5617877 ( R-HSA-5617472 ) R-HSA-5617877 Reaction Name: HOXA4 gene is transcribed See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-6804383 ( R-HSA-6804760 ) R-HSA-6804383 Reaction Name: PRMT5 methylates TP53 See in Reactome R-HSA-6782234 ( R-HSA-6781827 ) R-HSA-6782234 Reaction Name: Recovery of RNA synthesis after TC-NER See in Reactome R-HSA-9011975 ( R-HSA-9018519 ) R-HSA-9011975 Reaction Name: Estrogen-responsive MYC gene expression See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-2976551 ( R-HSA-2197563 ) R-HSA-2976551 Reaction Name: NOTCH2 stimulates GZMB transcription See in Reactome R-HSA-1368081 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-1368081 Reaction Name: Expression of SREBF1 (SREBP1) See in Reactome R-HSA-5617431 ( R-HSA-5617472 ) R-HSA-5617431 Reaction Name: Retinoic acid activates HOXA1 chromatin See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-3215152 ( R-HSA-6804114 ) R-HSA-3215152 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter See in Reactome R-HSA-4088152 ( R-HSA-156711 ) R-HSA-4088152 Reaction Name: FOXM1 stimulates CDC25A transcription See in Reactome R-HSA-9009371 ( R-HSA-9018519 ) R-HSA-9009371 Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter See in Reactome R-HSA-9023859 ( R-HSA-9018519 ) R-HSA-9023859 Reaction Name: Estrogen-responsive TFF1 gene expression See in Reactome R-HSA-1368087 ( R-HSA-400253 ) R-HSA-1368087 Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-3899291 ( R-HSA-3899300 ) R-HSA-3899291 Reaction Name: SUMOylation of EP300 with SUMO1 See in Reactome R-HSA-9634433 ( R-HSA-9616222 ) R-HSA-9634433 Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid See in Reactome R-HSA-9605057 ( R-HSA-9029569 ) R-HSA-9605057 Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 See in Reactome R-HSA-5617471 ( R-HSA-5617472 ) R-HSA-5617471 Reaction Name: HOXA1 gene is transcribed See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-5691381 ( R-HSA-5689901 ) R-HSA-5691381 Reaction Name: MYSM1 deubiquitinates Histone H2A See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9018499 ( R-HSA-9018519 ) R-HSA-9018499 Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-6782131 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782131 Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-8935740 ( R-HSA-8936459 ) R-HSA-8935740 Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene See in Reactome R-HSA-9009378 ( R-HSA-9018519 ) R-HSA-9009378 Reaction Name: Estrogen-responsive CCND1 gene expression See in Reactome R-HSA-8952419 ( R-HSA-8941858 ) R-HSA-8952419 Reaction Name: SMURFs ubiquitinate RUNX3 See in Reactome R-HSA-6782224 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782224 Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER See in Reactome R-HSA-8936979 ( R-HSA-8936459 ) R-HSA-8936979 Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-3215144 ( R-HSA-6804114 ) R-HSA-3215144 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription See in Reactome R-HSA-8951966 ( R-HSA-8951936 ) R-HSA-8951966 Reaction Name: EP300 acetylates RUNX3 See in Reactome R-HSA-9008271 ( R-HSA-9018519 ) R-HSA-9008271 Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter See in Reactome R-HSA-9011941 ( R-HSA-9018519 ) R-HSA-9011941 Reaction Name: Estrogen-responsive BCL2 gene expression See in Reactome R-HSA-2976563 ( R-HSA-2197563 ) R-HSA-2976563 Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter See in Reactome R-HSA-5663273 ( R-HSA-400253 ) R-HSA-5663273 Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-6782141 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782141 Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-8937037 ( R-HSA-8936459 ) R-HSA-8937037 Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-9617735 ( R-HSA-9617629 ) R-HSA-9617735 Reaction Name: TXN disrupts FOXO4 complex with EP300 See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-9018497 ( R-HSA-9018519 ) R-HSA-9018497 Reaction Name: Estrogen-responsive TFF3 gene expression See in Reactome R-HSA-8936995 ( R-HSA-8936459 ) R-HSA-8936995 Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9684118 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-9684118 Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-6804242 ( R-HSA-6804760 ) R-HSA-6804242 Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5 See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-3222093 ( R-HSA-6804758 ) R-HSA-3222093 Reaction Name: BRD7 binds TP53 and EP300 See in Reactome
MONDO:0007759	LPL	P06858	3.1.1.34 3.1.1.32	R-HSA-8963889 R-HSA-8963889 Reactome Name: Assembly of active LPL and LIPC lipase complexes See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-8963901 R-HSA-8963901 Reactome Name: Chylomicron remodeling See in Reactome R-HSA-975634 R-HSA-975634 Reactome Name: Retinoid metabolism and transport See in Reactome	R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-6806667 R-HSA-6806667 Reactome Name: Metabolism of fat-soluble vitamins See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8963899 R-HSA-8963899 Reactome Name: Plasma lipoprotein remodeling See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Transport of small molecules Sensory Perception Metabolism Developmental Biology	R-HSA-174757 ( R-HSA-8963901 ) R-HSA-174757 Reaction Name: chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols See in Reactome R-HSA-2395768 ( R-HSA-975634 ) R-HSA-2395768 Reaction Name: LPL hydrolyses TGs from mature CMs See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-6784628 ( R-HSA-8963889 ) R-HSA-6784628 Reaction Name: PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer See in Reactome R-HSA-6784676 ( R-HSA-8963889 ) R-HSA-6784676 Reaction Name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer See in Reactome R-HSA-6784861 ( R-HSA-8963889 ) R-HSA-6784861 Reaction Name: HSPG binds LPL dimer See in Reactome R-HSA-8857928 ( R-HSA-8963889 ) R-HSA-8857928 Reaction Name: GPIHBP1 binds HSPG:LPL dimer See in Reactome
MONDO:0007790	EGR2	P11161	2.3.2.-	R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Developmental Biology Signal Transduction	R-HSA-381337 ( R-HSA-381340 ) R-HSA-381337 Reaction Name: Expression of CEBPB in adipogenesis See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-5617483 ( R-HSA-5617472 ) R-HSA-5617483 Reaction Name: HOXA2 gene is transcribed See in Reactome R-HSA-5617484 ( R-HSA-5617472 ) R-HSA-5617484 Reaction Name: EGR2 (KROX20) activates HOXA2 expression See in Reactome R-HSA-5617486 ( R-HSA-5617472 ) R-HSA-5617486 Reaction Name: HOXB2 gene is transcribed See in Reactome R-HSA-5617492 ( R-HSA-5617472 ) R-HSA-5617492 Reaction Name: EGR2 (KROX20) activates HOXB2 expression See in Reactome R-HSA-5617661 ( R-HSA-5617472 ) R-HSA-5617661 Reaction Name: MAFB:JUN and EGR2 activate HOXB3 expression See in Reactome R-HSA-5617672 ( R-HSA-5617472 ) R-HSA-5617672 Reaction Name: HOXB3 gene is transcribed See in Reactome R-HSA-9031616 ( R-HSA-9031628 ) R-HSA-9031616 Reaction Name: EGR binds ARC gene See in Reactome R-HSA-9031624 ( R-HSA-9031628 ) R-HSA-9031624 Reaction Name: ARC gene expression See in Reactome R-HSA-9612073 ( R-HSA-9031628 ) R-HSA-9612073 Reaction Name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression See in Reactome R-HSA-9612483 ( R-HSA-9031628 ) R-HSA-9612483 Reaction Name: EGR1,2,3 bind the NAB2 promoter See in Reactome R-HSA-9612493 ( R-HSA-9031628 ) R-HSA-9612493 Reaction Name: EGR-dependent NAB2 gene expression See in Reactome R-HSA-9612534 ( R-HSA-9031628 ) R-HSA-9612534 Reaction Name: Expression of ID2 and ID4 is repressed by EGR2:NAB See in Reactome R-HSA-9613210 ( R-HSA-9031628 ) R-HSA-9613210 Reaction Name: EGR1, EGR2 bind the RRAD promoter See in Reactome R-HSA-9613213 ( R-HSA-9031628 ) R-HSA-9613213 Reaction Name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression See in Reactome R-HSA-9613219 ( R-HSA-9031628 ) R-HSA-9613219 Reaction Name: RRAD gene expression See in Reactome R-HSA-9613476 ( R-HSA-9031628 ) R-HSA-9613476 Reaction Name: EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions See in Reactome R-HSA-9613760 ( R-HSA-9619665 ) R-HSA-9613760 Reaction Name: EGR2 gene expression See in Reactome R-HSA-9614773 ( R-HSA-9619665 ) R-HSA-9614773 Reaction Name: MBP gene expression See in Reactome R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome R-HSA-9615626 ( R-HSA-9619665 ) R-HSA-9615626 Reaction Name: PMP22 gene expression See in Reactome R-HSA-9615638 ( R-HSA-9619665 ) R-HSA-9615638 Reaction Name: EGR2 and SOX10 bind the MBP gene See in Reactome R-HSA-9616116 ( R-HSA-9619665 ) R-HSA-9616116 Reaction Name: EGR2 and SOX10 bind the MAG gene See in Reactome R-HSA-9618559 ( R-HSA-9619665 ) R-HSA-9618559 Reaction Name: EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene See in Reactome R-HSA-9618725 ( R-HSA-9619665 ) R-HSA-9618725 Reaction Name: SOX10, EGR2 and NAB proteins bind the GJB1 promoter See in Reactome R-HSA-9619657 ( R-HSA-9619665 ) R-HSA-9619657 Reaction Name: EGR2 and SOX10 bind the PRX gene See in Reactome R-HSA-9619667 ( R-HSA-9619665 ) R-HSA-9619667 Reaction Name: PRX gene expression See in Reactome R-HSA-9621399 ( R-HSA-9619665 ) R-HSA-9621399 Reaction Name: SCD5 gene expression See in Reactome R-HSA-9621400 ( R-HSA-9619665 ) R-HSA-9621400 Reaction Name: EGR2 and SREBF2 dimer bind SCD5 gene See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome R-HSA-9621406 ( R-HSA-9619665 ) R-HSA-9621406 Reaction Name: EGR2 and SREBF2 dimer bind CYP51A1 gene See in Reactome R-HSA-9621410 ( R-HSA-9619665 ) R-HSA-9621410 Reaction Name: HMGCR gene expression See in Reactome R-HSA-9621411 ( R-HSA-9619665 ) R-HSA-9621411 Reaction Name: EGR2 and SREBF2(1-484) dimer bind HMGCR gene See in Reactome
MONDO:0007959	EP300	Q09472	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-5689901 R-HSA-5689901 Reactome Name: Metalloprotease DUBs See in Reactome R-HSA-6804760 R-HSA-6804760 Reactome Name: Regulation of TP53 Activity through Methylation See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-6782135 R-HSA-6782135 Reactome Name: Dual incision in TC-NER See in Reactome R-HSA-6782210 R-HSA-6782210 Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-6804114 R-HSA-6804114 Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-6781827 R-HSA-6781827 Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER) See in Reactome R-HSA-156711 R-HSA-156711 Reactome Name: Polo-like kinase mediated events See in Reactome R-HSA-5250924 R-HSA-5250924 Reactome Name: B-WICH complex positively regulates rRNA expression See in Reactome R-HSA-6781823 R-HSA-6781823 Reactome Name: Formation of TC-NER Pre-Incision Complex See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-9701898 R-HSA-9701898 Reactome Name: STAT3 nuclear events downstream of ALK signaling See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8936459 R-HSA-8936459 Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2197563 R-HSA-2197563 Reactome Name: NOTCH2 intracellular domain regulates transcription See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8951936 R-HSA-8951936 Reactome Name: RUNX3 regulates p14-ARF See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-6811555 R-HSA-6811555 Reactome Name: PI5P Regulates TP53 Acetylation See in Reactome R-HSA-6804758 R-HSA-6804758 Reactome Name: Regulation of TP53 Activity through Acetylation See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-6791312 R-HSA-6791312 Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-5696398 R-HSA-5696398 Reactome Name: Nucleotide Excision Repair See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-1980145 R-HSA-1980145 Reactome Name: Signaling by NOTCH2 See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-5250913 R-HSA-5250913 Reactome Name: Positive epigenetic regulation of rRNA expression See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome	Circadian Clock Immune System Cell Cycle Developmental Biology Metabolism Gene expression (Transcription) DNA Repair Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-6782069 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782069 Reaction Name: UVSSA:USP7 deubiquitinates ERCC6 See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome R-HSA-9011981 ( R-HSA-9018519 ) R-HSA-9011981 Reaction Name: EP300 is recruited to MYC and BCL2 genes See in Reactome R-HSA-8878050 ( R-HSA-8939243 ) R-HSA-8878050 Reaction Name: HIPK2 phosphorylates RUNX1 and EP300 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-8952101 ( R-HSA-8951936 ) R-HSA-8952101 Reaction Name: p14-ARF transcription is stimulated by RUNX proteins See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9038163 ( R-HSA-9018519 ) R-HSA-9038163 Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-6782211 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782211 Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-9613451 ( R-HSA-9031628 ) R-HSA-9613451 Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes See in Reactome R-HSA-8936621 ( R-HSA-8936459 ) R-HSA-8936621 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter See in Reactome R-HSA-5628871 ( R-HSA-6804758 ) R-HSA-5628871 Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9620723 ( R-HSA-9031628 ) R-HSA-9620723 Reaction Name: VGF gene expression See in Reactome R-HSA-5250938 ( R-HSA-5250924 ) R-HSA-5250938 Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 See in Reactome R-HSA-6782204 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782204 Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER See in Reactome R-HSA-5617867 ( R-HSA-5617472 ) R-HSA-5617867 Reaction Name: HOXB4 gene is transcribed See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-9023884 ( R-HSA-9018519 ) R-HSA-9023884 Reaction Name: NCOA1 recruits EP300 to TGFA promoter See in Reactome R-HSA-8937050 ( R-HSA-8936459 ) R-HSA-8937050 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter See in Reactome R-HSA-8952081 ( R-HSA-8951936 ) R-HSA-8952081 Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus See in Reactome R-HSA-3662335 ( R-HSA-3214847 ) R-HSA-3662335 Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4 See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-6804379 ( R-HSA-6804760 ) R-HSA-6804379 Reaction Name: PRMT5 binds TTC5 See in Reactome R-HSA-4088162 ( R-HSA-156711 ) R-HSA-4088162 Reaction Name: FOXM1 binds CDC25A promoter See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-9023846 ( R-HSA-9018519 ) R-HSA-9023846 Reaction Name: Estrogen-responsive CTSD expression See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-9008315 ( R-HSA-9018519 ) R-HSA-9008315 Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen See in Reactome R-HSA-8936628 ( R-HSA-8936459 ) R-HSA-8936628 Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9023860 ( R-HSA-9018519 ) R-HSA-9023860 Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-8936481 ( R-HSA-8936459 ) R-HSA-8936481 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter See in Reactome R-HSA-5663264 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663264 Reaction Name: RORA, EP300 bind CPT1A gene See in Reactome R-HSA-6805650 ( R-HSA-6804758 ) R-HSA-6805650 Reaction Name: MTA2-NuRD complex deacetylates TP53 See in Reactome R-HSA-5617452 ( R-HSA-5617472 ) R-HSA-5617452 Reaction Name: Retinoic acid activates HOXB1 chromatin See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-9613460 ( R-HSA-9031628 ) R-HSA-9613460 Reaction Name: ID1 and ID3 gene expression See in Reactome R-HSA-9620717 ( R-HSA-9031628 ) R-HSA-9620717 Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter See in Reactome R-HSA-8951951 ( R-HSA-8951936 ) R-HSA-8951951 Reaction Name: RUNX3 binds EP300 See in Reactome R-HSA-9029561 ( R-HSA-9029569 ) R-HSA-9029561 Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-9617064 ( R-HSA-9616222 ) R-HSA-9617064 Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene See in Reactome R-HSA-9008285 ( R-HSA-9018519 ) R-HSA-9008285 Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-9701531 ( R-HSA-9701898 ) R-HSA-9701531 Reaction Name: p-Y705,S727 STAT3 is acetylated See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-8937097 ( R-HSA-8936459 ) R-HSA-8937097 Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-8936616 ( R-HSA-8936459 ) R-HSA-8936616 Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene See in Reactome R-HSA-5663246 ( R-HSA-400253 ) R-HSA-5663246 Reaction Name: RORA, EP300 bind NPAS2 gene See in Reactome R-HSA-6804229 ( R-HSA-6804760 ) R-HSA-6804229 Reaction Name: JMY, TTC5 and EP300 bind See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-8878056 ( R-HSA-8939243 ) R-HSA-8878056 Reaction Name: RUNX1:CBFB binds EP300 See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-6782004 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782004 Reaction Name: Assembly of the pre-incision complex in TC-NER See in Reactome R-HSA-5250930 ( R-HSA-5250924 ) R-HSA-5250930 Reaction Name: B-WICH recruits histone acetyltransferases See in Reactome R-HSA-8937016 ( R-HSA-8936459 ) R-HSA-8937016 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter See in Reactome R-HSA-400342 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-400342 Reaction Name: Expression of ARNTL (BMAL1) See in Reactome R-HSA-6782138 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782138 Reaction Name: ERCC5 and RPA bind TC-NER site See in Reactome R-HSA-5617859 ( R-HSA-5617472 ) R-HSA-5617859 Reaction Name: Retinoic acid activates HOXB4 chromatin See in Reactome R-HSA-8952058 ( R-HSA-8951936 ) R-HSA-8952058 Reaction Name: CCND1 binds RUNX3 and displaces EP300 See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-9620515 ( R-HSA-9617629 ) R-HSA-9620515 Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-5693644 ( R-HSA-5617472 ) R-HSA-5693644 Reaction Name: HOXB1 maintains activation of HOXB1 chromatin See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-5617862 ( R-HSA-5617472 ) R-HSA-5617862 Reaction Name: Retinoic acid activates HOXA4 chromatin See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-8935731 ( R-HSA-8936459 ) R-HSA-8935731 Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-6782208 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782208 Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER See in Reactome R-HSA-5663293 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663293 Reaction Name: RORA, EP300 bind SREBF1 gene See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-549475 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-549475 Reaction Name: Expression of NR1D1 (REV-ERBA) See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-6782227 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782227 Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER See in Reactome R-HSA-6811508 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811508 Reaction Name: ING2-bound EP300 acetylates TP53 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-8951977 ( R-HSA-8951936 ) R-HSA-8951977 Reaction Name: Acetylated RUNX3 binds to BRD2 See in Reactome R-HSA-9023840 ( R-HSA-9018519 ) R-HSA-9023840 Reaction Name: HATs and coactivators are recruited to the CTSD gene See in Reactome R-HSA-6811479 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811479 Reaction Name: ING2 recruits EP300 to TP53 See in Reactome R-HSA-5617877 ( R-HSA-5617472 ) R-HSA-5617877 Reaction Name: HOXA4 gene is transcribed See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-6804383 ( R-HSA-6804760 ) R-HSA-6804383 Reaction Name: PRMT5 methylates TP53 See in Reactome R-HSA-6782234 ( R-HSA-6781827 ) R-HSA-6782234 Reaction Name: Recovery of RNA synthesis after TC-NER See in Reactome R-HSA-9011975 ( R-HSA-9018519 ) R-HSA-9011975 Reaction Name: Estrogen-responsive MYC gene expression See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-2976551 ( R-HSA-2197563 ) R-HSA-2976551 Reaction Name: NOTCH2 stimulates GZMB transcription See in Reactome R-HSA-1368081 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-1368081 Reaction Name: Expression of SREBF1 (SREBP1) See in Reactome R-HSA-5617431 ( R-HSA-5617472 ) R-HSA-5617431 Reaction Name: Retinoic acid activates HOXA1 chromatin See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-3215152 ( R-HSA-6804114 ) R-HSA-3215152 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter See in Reactome R-HSA-4088152 ( R-HSA-156711 ) R-HSA-4088152 Reaction Name: FOXM1 stimulates CDC25A transcription See in Reactome R-HSA-9009371 ( R-HSA-9018519 ) R-HSA-9009371 Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter See in Reactome R-HSA-9023859 ( R-HSA-9018519 ) R-HSA-9023859 Reaction Name: Estrogen-responsive TFF1 gene expression See in Reactome R-HSA-1368087 ( R-HSA-400253 ) R-HSA-1368087 Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-3899291 ( R-HSA-3899300 ) R-HSA-3899291 Reaction Name: SUMOylation of EP300 with SUMO1 See in Reactome R-HSA-9634433 ( R-HSA-9616222 ) R-HSA-9634433 Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid See in Reactome R-HSA-9605057 ( R-HSA-9029569 ) R-HSA-9605057 Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 See in Reactome R-HSA-5617471 ( R-HSA-5617472 ) R-HSA-5617471 Reaction Name: HOXA1 gene is transcribed See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-5691381 ( R-HSA-5689901 ) R-HSA-5691381 Reaction Name: MYSM1 deubiquitinates Histone H2A See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9018499 ( R-HSA-9018519 ) R-HSA-9018499 Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-6782131 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782131 Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-8935740 ( R-HSA-8936459 ) R-HSA-8935740 Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene See in Reactome R-HSA-9009378 ( R-HSA-9018519 ) R-HSA-9009378 Reaction Name: Estrogen-responsive CCND1 gene expression See in Reactome R-HSA-8952419 ( R-HSA-8941858 ) R-HSA-8952419 Reaction Name: SMURFs ubiquitinate RUNX3 See in Reactome R-HSA-6782224 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782224 Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER See in Reactome R-HSA-8936979 ( R-HSA-8936459 ) R-HSA-8936979 Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-3215144 ( R-HSA-6804114 ) R-HSA-3215144 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription See in Reactome R-HSA-8951966 ( R-HSA-8951936 ) R-HSA-8951966 Reaction Name: EP300 acetylates RUNX3 See in Reactome R-HSA-9008271 ( R-HSA-9018519 ) R-HSA-9008271 Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter See in Reactome R-HSA-9011941 ( R-HSA-9018519 ) R-HSA-9011941 Reaction Name: Estrogen-responsive BCL2 gene expression See in Reactome R-HSA-2976563 ( R-HSA-2197563 ) R-HSA-2976563 Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter See in Reactome R-HSA-5663273 ( R-HSA-400253 ) R-HSA-5663273 Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-6782141 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782141 Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-8937037 ( R-HSA-8936459 ) R-HSA-8937037 Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-9617735 ( R-HSA-9617629 ) R-HSA-9617735 Reaction Name: TXN disrupts FOXO4 complex with EP300 See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-9018497 ( R-HSA-9018519 ) R-HSA-9018497 Reaction Name: Estrogen-responsive TFF3 gene expression See in Reactome R-HSA-8936995 ( R-HSA-8936459 ) R-HSA-8936995 Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9684118 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-9684118 Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-6804242 ( R-HSA-6804760 ) R-HSA-6804242 Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5 See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-3222093 ( R-HSA-6804758 ) R-HSA-3222093 Reaction Name: BRD7 binds TP53 and EP300 See in Reactome
MONDO:0008393	EP300	Q09472	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-5689901 R-HSA-5689901 Reactome Name: Metalloprotease DUBs See in Reactome R-HSA-6804760 R-HSA-6804760 Reactome Name: Regulation of TP53 Activity through Methylation See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-6782135 R-HSA-6782135 Reactome Name: Dual incision in TC-NER See in Reactome R-HSA-6782210 R-HSA-6782210 Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-6804114 R-HSA-6804114 Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-6781827 R-HSA-6781827 Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER) See in Reactome R-HSA-156711 R-HSA-156711 Reactome Name: Polo-like kinase mediated events See in Reactome R-HSA-5250924 R-HSA-5250924 Reactome Name: B-WICH complex positively regulates rRNA expression See in Reactome R-HSA-6781823 R-HSA-6781823 Reactome Name: Formation of TC-NER Pre-Incision Complex See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-9701898 R-HSA-9701898 Reactome Name: STAT3 nuclear events downstream of ALK signaling See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8936459 R-HSA-8936459 Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2197563 R-HSA-2197563 Reactome Name: NOTCH2 intracellular domain regulates transcription See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8951936 R-HSA-8951936 Reactome Name: RUNX3 regulates p14-ARF See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-6811555 R-HSA-6811555 Reactome Name: PI5P Regulates TP53 Acetylation See in Reactome R-HSA-6804758 R-HSA-6804758 Reactome Name: Regulation of TP53 Activity through Acetylation See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-6791312 R-HSA-6791312 Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-5696398 R-HSA-5696398 Reactome Name: Nucleotide Excision Repair See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-1980145 R-HSA-1980145 Reactome Name: Signaling by NOTCH2 See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-5250913 R-HSA-5250913 Reactome Name: Positive epigenetic regulation of rRNA expression See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome	Circadian Clock Immune System Cell Cycle Developmental Biology Metabolism Gene expression (Transcription) DNA Repair Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-6782069 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782069 Reaction Name: UVSSA:USP7 deubiquitinates ERCC6 See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome R-HSA-9011981 ( R-HSA-9018519 ) R-HSA-9011981 Reaction Name: EP300 is recruited to MYC and BCL2 genes See in Reactome R-HSA-8878050 ( R-HSA-8939243 ) R-HSA-8878050 Reaction Name: HIPK2 phosphorylates RUNX1 and EP300 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-8952101 ( R-HSA-8951936 ) R-HSA-8952101 Reaction Name: p14-ARF transcription is stimulated by RUNX proteins See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9038163 ( R-HSA-9018519 ) R-HSA-9038163 Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-6782211 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782211 Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-9613451 ( R-HSA-9031628 ) R-HSA-9613451 Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes See in Reactome R-HSA-8936621 ( R-HSA-8936459 ) R-HSA-8936621 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter See in Reactome R-HSA-5628871 ( R-HSA-6804758 ) R-HSA-5628871 Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9620723 ( R-HSA-9031628 ) R-HSA-9620723 Reaction Name: VGF gene expression See in Reactome R-HSA-5250938 ( R-HSA-5250924 ) R-HSA-5250938 Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 See in Reactome R-HSA-6782204 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782204 Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER See in Reactome R-HSA-5617867 ( R-HSA-5617472 ) R-HSA-5617867 Reaction Name: HOXB4 gene is transcribed See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-9023884 ( R-HSA-9018519 ) R-HSA-9023884 Reaction Name: NCOA1 recruits EP300 to TGFA promoter See in Reactome R-HSA-8937050 ( R-HSA-8936459 ) R-HSA-8937050 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter See in Reactome R-HSA-8952081 ( R-HSA-8951936 ) R-HSA-8952081 Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus See in Reactome R-HSA-3662335 ( R-HSA-3214847 ) R-HSA-3662335 Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4 See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-6804379 ( R-HSA-6804760 ) R-HSA-6804379 Reaction Name: PRMT5 binds TTC5 See in Reactome R-HSA-4088162 ( R-HSA-156711 ) R-HSA-4088162 Reaction Name: FOXM1 binds CDC25A promoter See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-9023846 ( R-HSA-9018519 ) R-HSA-9023846 Reaction Name: Estrogen-responsive CTSD expression See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-9008315 ( R-HSA-9018519 ) R-HSA-9008315 Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen See in Reactome R-HSA-8936628 ( R-HSA-8936459 ) R-HSA-8936628 Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9023860 ( R-HSA-9018519 ) R-HSA-9023860 Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-8936481 ( R-HSA-8936459 ) R-HSA-8936481 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter See in Reactome R-HSA-5663264 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663264 Reaction Name: RORA, EP300 bind CPT1A gene See in Reactome R-HSA-6805650 ( R-HSA-6804758 ) R-HSA-6805650 Reaction Name: MTA2-NuRD complex deacetylates TP53 See in Reactome R-HSA-5617452 ( R-HSA-5617472 ) R-HSA-5617452 Reaction Name: Retinoic acid activates HOXB1 chromatin See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-9613460 ( R-HSA-9031628 ) R-HSA-9613460 Reaction Name: ID1 and ID3 gene expression See in Reactome R-HSA-9620717 ( R-HSA-9031628 ) R-HSA-9620717 Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter See in Reactome R-HSA-8951951 ( R-HSA-8951936 ) R-HSA-8951951 Reaction Name: RUNX3 binds EP300 See in Reactome R-HSA-9029561 ( R-HSA-9029569 ) R-HSA-9029561 Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-9617064 ( R-HSA-9616222 ) R-HSA-9617064 Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene See in Reactome R-HSA-9008285 ( R-HSA-9018519 ) R-HSA-9008285 Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-9701531 ( R-HSA-9701898 ) R-HSA-9701531 Reaction Name: p-Y705,S727 STAT3 is acetylated See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-8937097 ( R-HSA-8936459 ) R-HSA-8937097 Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-8936616 ( R-HSA-8936459 ) R-HSA-8936616 Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene See in Reactome R-HSA-5663246 ( R-HSA-400253 ) R-HSA-5663246 Reaction Name: RORA, EP300 bind NPAS2 gene See in Reactome R-HSA-6804229 ( R-HSA-6804760 ) R-HSA-6804229 Reaction Name: JMY, TTC5 and EP300 bind See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-8878056 ( R-HSA-8939243 ) R-HSA-8878056 Reaction Name: RUNX1:CBFB binds EP300 See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-6782004 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782004 Reaction Name: Assembly of the pre-incision complex in TC-NER See in Reactome R-HSA-5250930 ( R-HSA-5250924 ) R-HSA-5250930 Reaction Name: B-WICH recruits histone acetyltransferases See in Reactome R-HSA-8937016 ( R-HSA-8936459 ) R-HSA-8937016 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter See in Reactome R-HSA-400342 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-400342 Reaction Name: Expression of ARNTL (BMAL1) See in Reactome R-HSA-6782138 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782138 Reaction Name: ERCC5 and RPA bind TC-NER site See in Reactome R-HSA-5617859 ( R-HSA-5617472 ) R-HSA-5617859 Reaction Name: Retinoic acid activates HOXB4 chromatin See in Reactome R-HSA-8952058 ( R-HSA-8951936 ) R-HSA-8952058 Reaction Name: CCND1 binds RUNX3 and displaces EP300 See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-9620515 ( R-HSA-9617629 ) R-HSA-9620515 Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-5693644 ( R-HSA-5617472 ) R-HSA-5693644 Reaction Name: HOXB1 maintains activation of HOXB1 chromatin See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-5617862 ( R-HSA-5617472 ) R-HSA-5617862 Reaction Name: Retinoic acid activates HOXA4 chromatin See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-8935731 ( R-HSA-8936459 ) R-HSA-8935731 Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-6782208 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782208 Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER See in Reactome R-HSA-5663293 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663293 Reaction Name: RORA, EP300 bind SREBF1 gene See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-549475 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-549475 Reaction Name: Expression of NR1D1 (REV-ERBA) See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-6782227 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782227 Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER See in Reactome R-HSA-6811508 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811508 Reaction Name: ING2-bound EP300 acetylates TP53 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-8951977 ( R-HSA-8951936 ) R-HSA-8951977 Reaction Name: Acetylated RUNX3 binds to BRD2 See in Reactome R-HSA-9023840 ( R-HSA-9018519 ) R-HSA-9023840 Reaction Name: HATs and coactivators are recruited to the CTSD gene See in Reactome R-HSA-6811479 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811479 Reaction Name: ING2 recruits EP300 to TP53 See in Reactome R-HSA-5617877 ( R-HSA-5617472 ) R-HSA-5617877 Reaction Name: HOXA4 gene is transcribed See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-6804383 ( R-HSA-6804760 ) R-HSA-6804383 Reaction Name: PRMT5 methylates TP53 See in Reactome R-HSA-6782234 ( R-HSA-6781827 ) R-HSA-6782234 Reaction Name: Recovery of RNA synthesis after TC-NER See in Reactome R-HSA-9011975 ( R-HSA-9018519 ) R-HSA-9011975 Reaction Name: Estrogen-responsive MYC gene expression See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-2976551 ( R-HSA-2197563 ) R-HSA-2976551 Reaction Name: NOTCH2 stimulates GZMB transcription See in Reactome R-HSA-1368081 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-1368081 Reaction Name: Expression of SREBF1 (SREBP1) See in Reactome R-HSA-5617431 ( R-HSA-5617472 ) R-HSA-5617431 Reaction Name: Retinoic acid activates HOXA1 chromatin See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-3215152 ( R-HSA-6804114 ) R-HSA-3215152 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter See in Reactome R-HSA-4088152 ( R-HSA-156711 ) R-HSA-4088152 Reaction Name: FOXM1 stimulates CDC25A transcription See in Reactome R-HSA-9009371 ( R-HSA-9018519 ) R-HSA-9009371 Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter See in Reactome R-HSA-9023859 ( R-HSA-9018519 ) R-HSA-9023859 Reaction Name: Estrogen-responsive TFF1 gene expression See in Reactome R-HSA-1368087 ( R-HSA-400253 ) R-HSA-1368087 Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-3899291 ( R-HSA-3899300 ) R-HSA-3899291 Reaction Name: SUMOylation of EP300 with SUMO1 See in Reactome R-HSA-9634433 ( R-HSA-9616222 ) R-HSA-9634433 Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid See in Reactome R-HSA-9605057 ( R-HSA-9029569 ) R-HSA-9605057 Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 See in Reactome R-HSA-5617471 ( R-HSA-5617472 ) R-HSA-5617471 Reaction Name: HOXA1 gene is transcribed See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-5691381 ( R-HSA-5689901 ) R-HSA-5691381 Reaction Name: MYSM1 deubiquitinates Histone H2A See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9018499 ( R-HSA-9018519 ) R-HSA-9018499 Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-6782131 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782131 Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-8935740 ( R-HSA-8936459 ) R-HSA-8935740 Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene See in Reactome R-HSA-9009378 ( R-HSA-9018519 ) R-HSA-9009378 Reaction Name: Estrogen-responsive CCND1 gene expression See in Reactome R-HSA-8952419 ( R-HSA-8941858 ) R-HSA-8952419 Reaction Name: SMURFs ubiquitinate RUNX3 See in Reactome R-HSA-6782224 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782224 Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER See in Reactome R-HSA-8936979 ( R-HSA-8936459 ) R-HSA-8936979 Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-3215144 ( R-HSA-6804114 ) R-HSA-3215144 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription See in Reactome R-HSA-8951966 ( R-HSA-8951936 ) R-HSA-8951966 Reaction Name: EP300 acetylates RUNX3 See in Reactome R-HSA-9008271 ( R-HSA-9018519 ) R-HSA-9008271 Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter See in Reactome R-HSA-9011941 ( R-HSA-9018519 ) R-HSA-9011941 Reaction Name: Estrogen-responsive BCL2 gene expression See in Reactome R-HSA-2976563 ( R-HSA-2197563 ) R-HSA-2976563 Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter See in Reactome R-HSA-5663273 ( R-HSA-400253 ) R-HSA-5663273 Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-6782141 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782141 Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-8937037 ( R-HSA-8936459 ) R-HSA-8937037 Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-9617735 ( R-HSA-9617629 ) R-HSA-9617735 Reaction Name: TXN disrupts FOXO4 complex with EP300 See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-9018497 ( R-HSA-9018519 ) R-HSA-9018497 Reaction Name: Estrogen-responsive TFF3 gene expression See in Reactome R-HSA-8936995 ( R-HSA-8936459 ) R-HSA-8936995 Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9684118 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-9684118 Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-6804242 ( R-HSA-6804760 ) R-HSA-6804242 Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5 See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-3222093 ( R-HSA-6804758 ) R-HSA-3222093 Reaction Name: BRD7 binds TP53 and EP300 See in Reactome
MONDO:0008393	CREBBP	Q92793	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-8939246 R-HSA-8939246 Reactome Name: RUNX1 regulates transcription of genes involved in differentiation of myeloid cells See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2151201 R-HSA-2151201 Reactome Name: Transcriptional activation of mitochondrial biogenesis See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-350054 R-HSA-350054 Reactome Name: Notch-HLH transcription pathway See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-6803204 R-HSA-6803204 Reactome Name: TP53 Regulates Transcription of Genes Involved in Cytochrome C Release See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-1368108 R-HSA-1368108 Reactome Name: BMAL1:CLOCK,NPAS2 activates circadian gene expression See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9707564 R-HSA-9707564 Reactome Name: Cytoprotection by HMOX1 See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-1592230 R-HSA-1592230 Reactome Name: Mitochondrial biogenesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5633008 R-HSA-5633008 Reactome Name: TP53 Regulates Transcription of Cell Death Genes See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-1852241 R-HSA-1852241 Reactome Name: Organelle biogenesis and maintenance See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-9711123 R-HSA-9711123 Reactome Name: Cellular response to chemical stress See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome	Circadian Clock Immune System Metabolism Developmental Biology Gene expression (Transcription) Organelle biogenesis and maintenance Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-1989746 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989746 Reaction Name: Expression of CYP7A1 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-1989756 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989756 Reaction Name: Expression of ME1 See in Reactome R-HSA-1989754 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989754 Reaction Name: Expression of APOA1 See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-1989755 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989755 Reaction Name: Expression of CYP4A11 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-1989753 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989753 Reaction Name: Expression of PEX11A See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-8938231 ( R-HSA-8939246 ) R-HSA-8938231 Reaction Name: RUNX1:CBFB binds CREBBP See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-400143 ( R-HSA-400206; R-HSA-9707564 ) R-HSA-400143 Reaction Name: Fatty acid ligands activate PPARA See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-1592238 ( R-HSA-1989781; R-HSA-2151201; R-HSA-400206 ) R-HSA-1592238 Reaction Name: Expression of ALAS1 See in Reactome R-HSA-1989751 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989751 Reaction Name: Expression of FABP1 See in Reactome R-HSA-1989777 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989777 Reaction Name: Expression of RGL1 See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-1989745 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989745 Reaction Name: Expression of ACADM See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-1989772 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989772 Reaction Name: Expression of GLIPR1 See in Reactome R-HSA-1989771 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989771 Reaction Name: Expression of TNFRSF21 See in Reactome R-HSA-1655850 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655850 Reaction Name: Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) See in Reactome R-HSA-3927959 ( R-HSA-3899300 ) R-HSA-3927959 Reaction Name: SUMOylation of CREBBP with SUMO1 See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400206; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-212356 ( R-HSA-350054 ) R-HSA-212356 Reaction Name: Formation of CSL-NICD coactivator complex See in Reactome R-HSA-879724 ( R-HSA-1368108; R-HSA-1989781; R-HSA-400206; R-HSA-400253 ) R-HSA-879724 Reaction Name: Expression of PPARA See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-9626945 ( R-HSA-9617629 ) R-HSA-9626945 Reaction Name: CREBBP acetylates FOXO1 See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-6798004 ( R-HSA-6803204 ) R-HSA-6798004 Reaction Name: TP53 stimulates BNIP3L expression See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-1989773 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989773 Reaction Name: Expression of CPT2 See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-8938228 ( R-HSA-8939246 ) R-HSA-8938228 Reaction Name: RUNX1:CBFB:CREBBP binds the CSF2 (GM-CSF) gene promoter See in Reactome R-HSA-1989765 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989765 Reaction Name: Expression of ABCA1 See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-1989764 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989764 Reaction Name: Expression of CYP1A1 See in Reactome R-HSA-1989758 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989758 Reaction Name: Expression of UGT1A9 See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1989750 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989750 Reaction Name: Expression of FATP1 (SLC27A1) See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-1989775 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989775 Reaction Name: Expression of SULT2A1 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-1989747 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989747 Reaction Name: Expression of FHL2 See in Reactome R-HSA-1989776 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989776 Reaction Name: Expression of APOA2 See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-3697008 ( R-HSA-3214847 ) R-HSA-3697008 Reaction Name: CREBBP acetylates histone H2B, H3, H4 See in Reactome R-HSA-1989760 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989760 Reaction Name: Expression of HMGCS2 See in Reactome R-HSA-1989770 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989770 Reaction Name: Expression of PLIN2 See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-1989762 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989762 Reaction Name: Expression of ABCB4 See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-9626928 ( R-HSA-9617629 ) R-HSA-9626928 Reaction Name: CREBBP binds FOXO1 See in Reactome R-HSA-1989757 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989757 Reaction Name: Expression of FADS1 See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400206; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-1989778 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989778 Reaction Name: Expression of ACSL1 See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-1989767 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989767 Reaction Name: Expression of TRIB3 See in Reactome R-HSA-8938251 ( R-HSA-8939246 ) R-HSA-8938251 Reaction Name: CSF2 (GM-CSF) gene expression is stimulated by RUNX1 and CREBBP See in Reactome R-HSA-1989748 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989748 Reaction Name: Expression of GRHL1 See in Reactome R-HSA-4395227 ( R-HSA-1912408 ) R-HSA-4395227 Reaction Name: CCND1:CREBBP binds NOTCH1 promoter See in Reactome R-HSA-1989779 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989779 Reaction Name: Expression of ANKRD1 See in Reactome R-HSA-1989759 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989759 Reaction Name: Expression of G0S2 See in Reactome R-HSA-1655848 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655848 Reaction Name: Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-1989752 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989752 Reaction Name: Expression of TXNRD1 See in Reactome R-HSA-1989749 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989749 Reaction Name: Expression of ACOX1 See in Reactome R-HSA-1989761 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989761 Reaction Name: Expression of APOA5 See in Reactome R-HSA-1989768 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989768 Reaction Name: Expression of TIAM2 See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-1655826 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655826 Reaction Name: Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) See in Reactome R-HSA-1989774 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989774 Reaction Name: Expression of AGT See in Reactome R-HSA-6797993 ( R-HSA-6803204 ) R-HSA-6797993 Reaction Name: TP53 and CREBBP bind BNIP3L gene See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome
MONDO:0009387	LPL	P06858	3.1.1.34 3.1.1.32	R-HSA-8963889 R-HSA-8963889 Reactome Name: Assembly of active LPL and LIPC lipase complexes See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-8963901 R-HSA-8963901 Reactome Name: Chylomicron remodeling See in Reactome R-HSA-975634 R-HSA-975634 Reactome Name: Retinoid metabolism and transport See in Reactome	R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-6806667 R-HSA-6806667 Reactome Name: Metabolism of fat-soluble vitamins See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8963899 R-HSA-8963899 Reactome Name: Plasma lipoprotein remodeling See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Transport of small molecules Sensory Perception Metabolism Developmental Biology	R-HSA-174757 ( R-HSA-8963901 ) R-HSA-174757 Reaction Name: chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols See in Reactome R-HSA-2395768 ( R-HSA-975634 ) R-HSA-2395768 Reaction Name: LPL hydrolyses TGs from mature CMs See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-6784628 ( R-HSA-8963889 ) R-HSA-6784628 Reaction Name: PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer See in Reactome R-HSA-6784676 ( R-HSA-8963889 ) R-HSA-6784676 Reaction Name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer See in Reactome R-HSA-6784861 ( R-HSA-8963889 ) R-HSA-6784861 Reaction Name: HSPG binds LPL dimer See in Reactome R-HSA-8857928 ( R-HSA-8963889 ) R-HSA-8857928 Reaction Name: GPIHBP1 binds HSPG:LPL dimer See in Reactome
MONDO:0009693	CDK4	P11802	2.7.11.22	R-HSA-2559585 R-HSA-2559585 Reactome Name: Oncogene Induced Senescence See in Reactome R-HSA-2559580 R-HSA-2559580 Reactome Name: Oxidative Stress Induced Senescence See in Reactome R-HSA-2559582 R-HSA-2559582 Reactome Name: Senescence-Associated Secretory Phenotype (SASP) See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-912446 R-HSA-912446 Reactome Name: Meiotic recombination See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-8849470 R-HSA-8849470 Reactome Name: PTK6 Regulates Cell Cycle See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-75815 R-HSA-75815 Reactome Name: Ubiquitin-dependent degradation of Cyclin D See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-187577 R-HSA-187577 Reactome Name: SCF(Skp2)-mediated degradation of p27/p21 See in Reactome	R-HSA-8848021 R-HSA-8848021 Reactome Name: Signaling by PTK6 See in Reactome R-HSA-2559583 R-HSA-2559583 Reactome Name: Cellular Senescence See in Reactome R-HSA-9006927 R-HSA-9006927 Reactome Name: Signaling by Non-Receptor Tyrosine Kinases See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1474165 R-HSA-1474165 Reactome Name: Reproduction See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-69656 R-HSA-69656 Reactome Name: Cyclin A:Cdk2-associated events at S phase entry See in Reactome R-HSA-69206 R-HSA-69206 Reactome Name: G1/S Transition See in Reactome R-HSA-69202 R-HSA-69202 Reactome Name: Cyclin E associated events during G1/S transition See in Reactome R-HSA-69242 R-HSA-69242 Reactome Name: S Phase See in Reactome R-HSA-1500620 R-HSA-1500620 Reactome Name: Meiosis See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction	R-HSA-1226094 ( R-HSA-69231 ) R-HSA-1226094 Reaction Name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex See in Reactome R-HSA-1226095 ( R-HSA-69231 ) R-HSA-1226095 Reaction Name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex See in Reactome R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-182594 Reaction Name: Association of INK4 family proteins with CDK4/6 See in Reactome R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215385 Reaction Name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 See in Reactome R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-3215426 Reaction Name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 See in Reactome R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-5216234 Reaction Name: PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-5661117 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 See in Reactome R-HSA-69227 ( R-HSA-69231 ) R-HSA-69227 Reaction Name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-75820 ( R-HSA-75815 ) R-HSA-75820 Reaction Name: Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta See in Reactome R-HSA-75822 ( R-HSA-75815 ) R-HSA-75822 Reaction Name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm See in Reactome R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848414 Reaction Name: Activated PTK6 binds CDKN1B See in Reactome R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 Reaction Name: PTK6 phosphorylates CDKN1B See in Reactome R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941895 Reaction Name: Formation of CDK4/6:CCND complexes See in Reactome R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8941915 Reaction Name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes See in Reactome R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942607 Reaction Name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes See in Reactome R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942803 Reaction Name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus See in Reactome R-HSA-8942836 ( R-HSA-69231 ) R-HSA-8942836 Reaction Name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 See in Reactome R-HSA-9008412 ( R-HSA-212436; R-HSA-8878166 ) R-HSA-9008412 Reaction Name: CDK4 phosphorylates RUNX2 See in Reactome R-HSA-9018017 ( R-HSA-69231 ) R-HSA-9018017 Reaction Name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-912429 ( R-HSA-912446 ) R-HSA-912429 Reaction Name: Resolution of meiotic holliday junction See in Reactome R-HSA-912458 ( R-HSA-912446 ) R-HSA-912458 Reaction Name: Formation of meiotic heteroduplex See in Reactome R-HSA-912496 ( R-HSA-912446 ) R-HSA-912496 Reaction Name: Formation of meiotic holliday junction See in Reactome R-HSA-912503 ( R-HSA-912446 ) R-HSA-912503 Reaction Name: Formation of meiotic single-stranded DNA invasion complex See in Reactome R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9624112 Reaction Name: CEBPA binds CDK4 See in Reactome R-HSA-9754130 ( R-HSA-69231 ) R-HSA-9754130 Reaction Name: CDK4 inhibitors bind CDK4 See in Reactome
MONDO:0009866	PCK1	P35558	4.1.1.32 2.7.11.-	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-9615017 R-HSA-9615017 Reactome Name: FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9632974 R-HSA-9632974 Reactome Name: NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis See in Reactome	R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Signal Transduction Developmental Biology	R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-70241 ( R-HSA-70263 ) R-HSA-70241 Reaction Name: oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] See in Reactome R-HSA-9605051 ( R-HSA-9632974 ) R-HSA-9605051 Reaction Name: Expression of PCK1 regulated by NR1H3 See in Reactome R-HSA-9623280 ( R-HSA-9615017 ) R-HSA-9623280 Reaction Name: PCK1 gene expression is stimulated by FOXO1:PPARGC1A See in Reactome
MONDO:0010150	EP300	Q09472	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-5689901 R-HSA-5689901 Reactome Name: Metalloprotease DUBs See in Reactome R-HSA-6804760 R-HSA-6804760 Reactome Name: Regulation of TP53 Activity through Methylation See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-6782135 R-HSA-6782135 Reactome Name: Dual incision in TC-NER See in Reactome R-HSA-6782210 R-HSA-6782210 Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-6804114 R-HSA-6804114 Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-6781827 R-HSA-6781827 Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER) See in Reactome R-HSA-156711 R-HSA-156711 Reactome Name: Polo-like kinase mediated events See in Reactome R-HSA-5250924 R-HSA-5250924 Reactome Name: B-WICH complex positively regulates rRNA expression See in Reactome R-HSA-6781823 R-HSA-6781823 Reactome Name: Formation of TC-NER Pre-Incision Complex See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-9701898 R-HSA-9701898 Reactome Name: STAT3 nuclear events downstream of ALK signaling See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8936459 R-HSA-8936459 Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2197563 R-HSA-2197563 Reactome Name: NOTCH2 intracellular domain regulates transcription See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8951936 R-HSA-8951936 Reactome Name: RUNX3 regulates p14-ARF See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-6811555 R-HSA-6811555 Reactome Name: PI5P Regulates TP53 Acetylation See in Reactome R-HSA-6804758 R-HSA-6804758 Reactome Name: Regulation of TP53 Activity through Acetylation See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-6791312 R-HSA-6791312 Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-5696398 R-HSA-5696398 Reactome Name: Nucleotide Excision Repair See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-1980145 R-HSA-1980145 Reactome Name: Signaling by NOTCH2 See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-5250913 R-HSA-5250913 Reactome Name: Positive epigenetic regulation of rRNA expression See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome	Circadian Clock Immune System Cell Cycle Developmental Biology Metabolism Gene expression (Transcription) DNA Repair Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-6782069 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782069 Reaction Name: UVSSA:USP7 deubiquitinates ERCC6 See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome R-HSA-9011981 ( R-HSA-9018519 ) R-HSA-9011981 Reaction Name: EP300 is recruited to MYC and BCL2 genes See in Reactome R-HSA-8878050 ( R-HSA-8939243 ) R-HSA-8878050 Reaction Name: HIPK2 phosphorylates RUNX1 and EP300 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-8952101 ( R-HSA-8951936 ) R-HSA-8952101 Reaction Name: p14-ARF transcription is stimulated by RUNX proteins See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9038163 ( R-HSA-9018519 ) R-HSA-9038163 Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-6782211 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782211 Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-9613451 ( R-HSA-9031628 ) R-HSA-9613451 Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes See in Reactome R-HSA-8936621 ( R-HSA-8936459 ) R-HSA-8936621 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter See in Reactome R-HSA-5628871 ( R-HSA-6804758 ) R-HSA-5628871 Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9620723 ( R-HSA-9031628 ) R-HSA-9620723 Reaction Name: VGF gene expression See in Reactome R-HSA-5250938 ( R-HSA-5250924 ) R-HSA-5250938 Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 See in Reactome R-HSA-6782204 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782204 Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER See in Reactome R-HSA-5617867 ( R-HSA-5617472 ) R-HSA-5617867 Reaction Name: HOXB4 gene is transcribed See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-9023884 ( R-HSA-9018519 ) R-HSA-9023884 Reaction Name: NCOA1 recruits EP300 to TGFA promoter See in Reactome R-HSA-8937050 ( R-HSA-8936459 ) R-HSA-8937050 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter See in Reactome R-HSA-8952081 ( R-HSA-8951936 ) R-HSA-8952081 Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus See in Reactome R-HSA-3662335 ( R-HSA-3214847 ) R-HSA-3662335 Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4 See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-6804379 ( R-HSA-6804760 ) R-HSA-6804379 Reaction Name: PRMT5 binds TTC5 See in Reactome R-HSA-4088162 ( R-HSA-156711 ) R-HSA-4088162 Reaction Name: FOXM1 binds CDC25A promoter See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-9023846 ( R-HSA-9018519 ) R-HSA-9023846 Reaction Name: Estrogen-responsive CTSD expression See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-9008315 ( R-HSA-9018519 ) R-HSA-9008315 Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen See in Reactome R-HSA-8936628 ( R-HSA-8936459 ) R-HSA-8936628 Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9023860 ( R-HSA-9018519 ) R-HSA-9023860 Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-8936481 ( R-HSA-8936459 ) R-HSA-8936481 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter See in Reactome R-HSA-5663264 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663264 Reaction Name: RORA, EP300 bind CPT1A gene See in Reactome R-HSA-6805650 ( R-HSA-6804758 ) R-HSA-6805650 Reaction Name: MTA2-NuRD complex deacetylates TP53 See in Reactome R-HSA-5617452 ( R-HSA-5617472 ) R-HSA-5617452 Reaction Name: Retinoic acid activates HOXB1 chromatin See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-9613460 ( R-HSA-9031628 ) R-HSA-9613460 Reaction Name: ID1 and ID3 gene expression See in Reactome R-HSA-9620717 ( R-HSA-9031628 ) R-HSA-9620717 Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter See in Reactome R-HSA-8951951 ( R-HSA-8951936 ) R-HSA-8951951 Reaction Name: RUNX3 binds EP300 See in Reactome R-HSA-9029561 ( R-HSA-9029569 ) R-HSA-9029561 Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-9617064 ( R-HSA-9616222 ) R-HSA-9617064 Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene See in Reactome R-HSA-9008285 ( R-HSA-9018519 ) R-HSA-9008285 Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-9701531 ( R-HSA-9701898 ) R-HSA-9701531 Reaction Name: p-Y705,S727 STAT3 is acetylated See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-8937097 ( R-HSA-8936459 ) R-HSA-8937097 Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-8936616 ( R-HSA-8936459 ) R-HSA-8936616 Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene See in Reactome R-HSA-5663246 ( R-HSA-400253 ) R-HSA-5663246 Reaction Name: RORA, EP300 bind NPAS2 gene See in Reactome R-HSA-6804229 ( R-HSA-6804760 ) R-HSA-6804229 Reaction Name: JMY, TTC5 and EP300 bind See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-8878056 ( R-HSA-8939243 ) R-HSA-8878056 Reaction Name: RUNX1:CBFB binds EP300 See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-6782004 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782004 Reaction Name: Assembly of the pre-incision complex in TC-NER See in Reactome R-HSA-5250930 ( R-HSA-5250924 ) R-HSA-5250930 Reaction Name: B-WICH recruits histone acetyltransferases See in Reactome R-HSA-8937016 ( R-HSA-8936459 ) R-HSA-8937016 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter See in Reactome R-HSA-400342 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-400342 Reaction Name: Expression of ARNTL (BMAL1) See in Reactome R-HSA-6782138 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782138 Reaction Name: ERCC5 and RPA bind TC-NER site See in Reactome R-HSA-5617859 ( R-HSA-5617472 ) R-HSA-5617859 Reaction Name: Retinoic acid activates HOXB4 chromatin See in Reactome R-HSA-8952058 ( R-HSA-8951936 ) R-HSA-8952058 Reaction Name: CCND1 binds RUNX3 and displaces EP300 See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-9620515 ( R-HSA-9617629 ) R-HSA-9620515 Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-5693644 ( R-HSA-5617472 ) R-HSA-5693644 Reaction Name: HOXB1 maintains activation of HOXB1 chromatin See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-5617862 ( R-HSA-5617472 ) R-HSA-5617862 Reaction Name: Retinoic acid activates HOXA4 chromatin See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-8935731 ( R-HSA-8936459 ) R-HSA-8935731 Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-6782208 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782208 Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER See in Reactome R-HSA-5663293 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663293 Reaction Name: RORA, EP300 bind SREBF1 gene See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-549475 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-549475 Reaction Name: Expression of NR1D1 (REV-ERBA) See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-6782227 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782227 Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER See in Reactome R-HSA-6811508 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811508 Reaction Name: ING2-bound EP300 acetylates TP53 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-8951977 ( R-HSA-8951936 ) R-HSA-8951977 Reaction Name: Acetylated RUNX3 binds to BRD2 See in Reactome R-HSA-9023840 ( R-HSA-9018519 ) R-HSA-9023840 Reaction Name: HATs and coactivators are recruited to the CTSD gene See in Reactome R-HSA-6811479 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811479 Reaction Name: ING2 recruits EP300 to TP53 See in Reactome R-HSA-5617877 ( R-HSA-5617472 ) R-HSA-5617877 Reaction Name: HOXA4 gene is transcribed See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-6804383 ( R-HSA-6804760 ) R-HSA-6804383 Reaction Name: PRMT5 methylates TP53 See in Reactome R-HSA-6782234 ( R-HSA-6781827 ) R-HSA-6782234 Reaction Name: Recovery of RNA synthesis after TC-NER See in Reactome R-HSA-9011975 ( R-HSA-9018519 ) R-HSA-9011975 Reaction Name: Estrogen-responsive MYC gene expression See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-2976551 ( R-HSA-2197563 ) R-HSA-2976551 Reaction Name: NOTCH2 stimulates GZMB transcription See in Reactome R-HSA-1368081 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-1368081 Reaction Name: Expression of SREBF1 (SREBP1) See in Reactome R-HSA-5617431 ( R-HSA-5617472 ) R-HSA-5617431 Reaction Name: Retinoic acid activates HOXA1 chromatin See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-3215152 ( R-HSA-6804114 ) R-HSA-3215152 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter See in Reactome R-HSA-4088152 ( R-HSA-156711 ) R-HSA-4088152 Reaction Name: FOXM1 stimulates CDC25A transcription See in Reactome R-HSA-9009371 ( R-HSA-9018519 ) R-HSA-9009371 Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter See in Reactome R-HSA-9023859 ( R-HSA-9018519 ) R-HSA-9023859 Reaction Name: Estrogen-responsive TFF1 gene expression See in Reactome R-HSA-1368087 ( R-HSA-400253 ) R-HSA-1368087 Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-3899291 ( R-HSA-3899300 ) R-HSA-3899291 Reaction Name: SUMOylation of EP300 with SUMO1 See in Reactome R-HSA-9634433 ( R-HSA-9616222 ) R-HSA-9634433 Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid See in Reactome R-HSA-9605057 ( R-HSA-9029569 ) R-HSA-9605057 Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 See in Reactome R-HSA-5617471 ( R-HSA-5617472 ) R-HSA-5617471 Reaction Name: HOXA1 gene is transcribed See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-5691381 ( R-HSA-5689901 ) R-HSA-5691381 Reaction Name: MYSM1 deubiquitinates Histone H2A See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9018499 ( R-HSA-9018519 ) R-HSA-9018499 Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-6782131 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782131 Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-8935740 ( R-HSA-8936459 ) R-HSA-8935740 Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene See in Reactome R-HSA-9009378 ( R-HSA-9018519 ) R-HSA-9009378 Reaction Name: Estrogen-responsive CCND1 gene expression See in Reactome R-HSA-8952419 ( R-HSA-8941858 ) R-HSA-8952419 Reaction Name: SMURFs ubiquitinate RUNX3 See in Reactome R-HSA-6782224 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782224 Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER See in Reactome R-HSA-8936979 ( R-HSA-8936459 ) R-HSA-8936979 Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-3215144 ( R-HSA-6804114 ) R-HSA-3215144 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription See in Reactome R-HSA-8951966 ( R-HSA-8951936 ) R-HSA-8951966 Reaction Name: EP300 acetylates RUNX3 See in Reactome R-HSA-9008271 ( R-HSA-9018519 ) R-HSA-9008271 Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter See in Reactome R-HSA-9011941 ( R-HSA-9018519 ) R-HSA-9011941 Reaction Name: Estrogen-responsive BCL2 gene expression See in Reactome R-HSA-2976563 ( R-HSA-2197563 ) R-HSA-2976563 Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter See in Reactome R-HSA-5663273 ( R-HSA-400253 ) R-HSA-5663273 Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-6782141 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782141 Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-8937037 ( R-HSA-8936459 ) R-HSA-8937037 Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-9617735 ( R-HSA-9617629 ) R-HSA-9617735 Reaction Name: TXN disrupts FOXO4 complex with EP300 See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-9018497 ( R-HSA-9018519 ) R-HSA-9018497 Reaction Name: Estrogen-responsive TFF3 gene expression See in Reactome R-HSA-8936995 ( R-HSA-8936459 ) R-HSA-8936995 Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9684118 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-9684118 Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-6804242 ( R-HSA-6804760 ) R-HSA-6804242 Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5 See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-3222093 ( R-HSA-6804758 ) R-HSA-3222093 Reaction Name: BRD7 binds TP53 and EP300 See in Reactome
MONDO:0011527	EGR2	P11161	2.3.2.-	R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Developmental Biology Signal Transduction	R-HSA-381337 ( R-HSA-381340 ) R-HSA-381337 Reaction Name: Expression of CEBPB in adipogenesis See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-5617483 ( R-HSA-5617472 ) R-HSA-5617483 Reaction Name: HOXA2 gene is transcribed See in Reactome R-HSA-5617484 ( R-HSA-5617472 ) R-HSA-5617484 Reaction Name: EGR2 (KROX20) activates HOXA2 expression See in Reactome R-HSA-5617486 ( R-HSA-5617472 ) R-HSA-5617486 Reaction Name: HOXB2 gene is transcribed See in Reactome R-HSA-5617492 ( R-HSA-5617472 ) R-HSA-5617492 Reaction Name: EGR2 (KROX20) activates HOXB2 expression See in Reactome R-HSA-5617661 ( R-HSA-5617472 ) R-HSA-5617661 Reaction Name: MAFB:JUN and EGR2 activate HOXB3 expression See in Reactome R-HSA-5617672 ( R-HSA-5617472 ) R-HSA-5617672 Reaction Name: HOXB3 gene is transcribed See in Reactome R-HSA-9031616 ( R-HSA-9031628 ) R-HSA-9031616 Reaction Name: EGR binds ARC gene See in Reactome R-HSA-9031624 ( R-HSA-9031628 ) R-HSA-9031624 Reaction Name: ARC gene expression See in Reactome R-HSA-9612073 ( R-HSA-9031628 ) R-HSA-9612073 Reaction Name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression See in Reactome R-HSA-9612483 ( R-HSA-9031628 ) R-HSA-9612483 Reaction Name: EGR1,2,3 bind the NAB2 promoter See in Reactome R-HSA-9612493 ( R-HSA-9031628 ) R-HSA-9612493 Reaction Name: EGR-dependent NAB2 gene expression See in Reactome R-HSA-9612534 ( R-HSA-9031628 ) R-HSA-9612534 Reaction Name: Expression of ID2 and ID4 is repressed by EGR2:NAB See in Reactome R-HSA-9613210 ( R-HSA-9031628 ) R-HSA-9613210 Reaction Name: EGR1, EGR2 bind the RRAD promoter See in Reactome R-HSA-9613213 ( R-HSA-9031628 ) R-HSA-9613213 Reaction Name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression See in Reactome R-HSA-9613219 ( R-HSA-9031628 ) R-HSA-9613219 Reaction Name: RRAD gene expression See in Reactome R-HSA-9613476 ( R-HSA-9031628 ) R-HSA-9613476 Reaction Name: EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions See in Reactome R-HSA-9613760 ( R-HSA-9619665 ) R-HSA-9613760 Reaction Name: EGR2 gene expression See in Reactome R-HSA-9614773 ( R-HSA-9619665 ) R-HSA-9614773 Reaction Name: MBP gene expression See in Reactome R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome R-HSA-9615626 ( R-HSA-9619665 ) R-HSA-9615626 Reaction Name: PMP22 gene expression See in Reactome R-HSA-9615638 ( R-HSA-9619665 ) R-HSA-9615638 Reaction Name: EGR2 and SOX10 bind the MBP gene See in Reactome R-HSA-9616116 ( R-HSA-9619665 ) R-HSA-9616116 Reaction Name: EGR2 and SOX10 bind the MAG gene See in Reactome R-HSA-9618559 ( R-HSA-9619665 ) R-HSA-9618559 Reaction Name: EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene See in Reactome R-HSA-9618725 ( R-HSA-9619665 ) R-HSA-9618725 Reaction Name: SOX10, EGR2 and NAB proteins bind the GJB1 promoter See in Reactome R-HSA-9619657 ( R-HSA-9619665 ) R-HSA-9619657 Reaction Name: EGR2 and SOX10 bind the PRX gene See in Reactome R-HSA-9619667 ( R-HSA-9619665 ) R-HSA-9619667 Reaction Name: PRX gene expression See in Reactome R-HSA-9621399 ( R-HSA-9619665 ) R-HSA-9621399 Reaction Name: SCD5 gene expression See in Reactome R-HSA-9621400 ( R-HSA-9619665 ) R-HSA-9621400 Reaction Name: EGR2 and SREBF2 dimer bind SCD5 gene See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome R-HSA-9621406 ( R-HSA-9619665 ) R-HSA-9621406 Reaction Name: EGR2 and SREBF2 dimer bind CYP51A1 gene See in Reactome R-HSA-9621410 ( R-HSA-9619665 ) R-HSA-9621410 Reaction Name: HMGCR gene expression See in Reactome R-HSA-9621411 ( R-HSA-9619665 ) R-HSA-9621411 Reaction Name: EGR2 and SREBF2(1-484) dimer bind HMGCR gene See in Reactome
MONDO:0011890	EGR2	P11161	2.3.2.-	R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Developmental Biology Signal Transduction	R-HSA-381337 ( R-HSA-381340 ) R-HSA-381337 Reaction Name: Expression of CEBPB in adipogenesis See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-5617483 ( R-HSA-5617472 ) R-HSA-5617483 Reaction Name: HOXA2 gene is transcribed See in Reactome R-HSA-5617484 ( R-HSA-5617472 ) R-HSA-5617484 Reaction Name: EGR2 (KROX20) activates HOXA2 expression See in Reactome R-HSA-5617486 ( R-HSA-5617472 ) R-HSA-5617486 Reaction Name: HOXB2 gene is transcribed See in Reactome R-HSA-5617492 ( R-HSA-5617472 ) R-HSA-5617492 Reaction Name: EGR2 (KROX20) activates HOXB2 expression See in Reactome R-HSA-5617661 ( R-HSA-5617472 ) R-HSA-5617661 Reaction Name: MAFB:JUN and EGR2 activate HOXB3 expression See in Reactome R-HSA-5617672 ( R-HSA-5617472 ) R-HSA-5617672 Reaction Name: HOXB3 gene is transcribed See in Reactome R-HSA-9031616 ( R-HSA-9031628 ) R-HSA-9031616 Reaction Name: EGR binds ARC gene See in Reactome R-HSA-9031624 ( R-HSA-9031628 ) R-HSA-9031624 Reaction Name: ARC gene expression See in Reactome R-HSA-9612073 ( R-HSA-9031628 ) R-HSA-9612073 Reaction Name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression See in Reactome R-HSA-9612483 ( R-HSA-9031628 ) R-HSA-9612483 Reaction Name: EGR1,2,3 bind the NAB2 promoter See in Reactome R-HSA-9612493 ( R-HSA-9031628 ) R-HSA-9612493 Reaction Name: EGR-dependent NAB2 gene expression See in Reactome R-HSA-9612534 ( R-HSA-9031628 ) R-HSA-9612534 Reaction Name: Expression of ID2 and ID4 is repressed by EGR2:NAB See in Reactome R-HSA-9613210 ( R-HSA-9031628 ) R-HSA-9613210 Reaction Name: EGR1, EGR2 bind the RRAD promoter See in Reactome R-HSA-9613213 ( R-HSA-9031628 ) R-HSA-9613213 Reaction Name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression See in Reactome R-HSA-9613219 ( R-HSA-9031628 ) R-HSA-9613219 Reaction Name: RRAD gene expression See in Reactome R-HSA-9613476 ( R-HSA-9031628 ) R-HSA-9613476 Reaction Name: EGR2:NAB2 and CHD4 bind the ID2 and ID4 promoter regions See in Reactome R-HSA-9613760 ( R-HSA-9619665 ) R-HSA-9613760 Reaction Name: EGR2 gene expression See in Reactome R-HSA-9614773 ( R-HSA-9619665 ) R-HSA-9614773 Reaction Name: MBP gene expression See in Reactome R-HSA-9614778 ( R-HSA-9619665 ) R-HSA-9614778 Reaction Name: MAG gene expression See in Reactome R-HSA-9614787 ( R-HSA-9619665 ) R-HSA-9614787 Reaction Name: MPZ gene expression See in Reactome R-HSA-9614790 ( R-HSA-9619665 ) R-HSA-9614790 Reaction Name: EGR2, SOX10 and SMARCA4 bind the MPZ gene See in Reactome R-HSA-9615626 ( R-HSA-9619665 ) R-HSA-9615626 Reaction Name: PMP22 gene expression See in Reactome R-HSA-9615638 ( R-HSA-9619665 ) R-HSA-9615638 Reaction Name: EGR2 and SOX10 bind the MBP gene See in Reactome R-HSA-9616116 ( R-HSA-9619665 ) R-HSA-9616116 Reaction Name: EGR2 and SOX10 bind the MAG gene See in Reactome R-HSA-9618559 ( R-HSA-9619665 ) R-HSA-9618559 Reaction Name: EGR2, SOX10 and TEAD1 bind enhancers in the PMP22 gene See in Reactome R-HSA-9618725 ( R-HSA-9619665 ) R-HSA-9618725 Reaction Name: SOX10, EGR2 and NAB proteins bind the GJB1 promoter See in Reactome R-HSA-9619657 ( R-HSA-9619665 ) R-HSA-9619657 Reaction Name: EGR2 and SOX10 bind the PRX gene See in Reactome R-HSA-9619667 ( R-HSA-9619665 ) R-HSA-9619667 Reaction Name: PRX gene expression See in Reactome R-HSA-9621399 ( R-HSA-9619665 ) R-HSA-9621399 Reaction Name: SCD5 gene expression See in Reactome R-HSA-9621400 ( R-HSA-9619665 ) R-HSA-9621400 Reaction Name: EGR2 and SREBF2 dimer bind SCD5 gene See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome R-HSA-9621406 ( R-HSA-9619665 ) R-HSA-9621406 Reaction Name: EGR2 and SREBF2 dimer bind CYP51A1 gene See in Reactome R-HSA-9621410 ( R-HSA-9619665 ) R-HSA-9621410 Reaction Name: HMGCR gene expression See in Reactome R-HSA-9621411 ( R-HSA-9619665 ) R-HSA-9621411 Reaction Name: EGR2 and SREBF2(1-484) dimer bind HMGCR gene See in Reactome
MONDO:0012031	CD36	P16671	-	R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-168188 R-HSA-168188 Reactome Name: Toll Like Receptor TLR6:TLR2 Cascade See in Reactome R-HSA-434313 R-HSA-434313 Reactome Name: Intracellular metabolism of fatty acids regulates insulin secretion See in Reactome R-HSA-114608 R-HSA-114608 Reactome Name: Platelet degranulation See in Reactome R-HSA-1236973 R-HSA-1236973 Reactome Name: Cross-presentation of particulate exogenous antigens (phagosomes) See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-1236974 R-HSA-1236974 Reactome Name: ER-Phagosome pathway See in Reactome R-HSA-3000471 R-HSA-3000471 Reactome Name: Scavenging by Class B Receptors See in Reactome R-HSA-166058 R-HSA-166058 Reactome Name: MyD88:MAL(TIRAP) cascade initiated on plasma membrane See in Reactome R-HSA-6785807 R-HSA-6785807 Reactome Name: Interleukin-4 and Interleukin-13 signaling See in Reactome R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-5686938 R-HSA-5686938 Reactome Name: Regulation of TLR by endogenous ligand See in Reactome	R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-400451 R-HSA-400451 Reactome Name: Free fatty acids regulate insulin secretion See in Reactome R-HSA-181438 R-HSA-181438 Reactome Name: Toll Like Receptor 2 (TLR2) Cascade See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome R-HSA-1236975 R-HSA-1236975 Reactome Name: Antigen processing-Cross presentation See in Reactome R-HSA-76005 R-HSA-76005 Reactome Name: Response to elevated platelet cytosolic Ca2+ See in Reactome R-HSA-168898 R-HSA-168898 Reactome Name: Toll-like Receptor Cascades See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-166016 R-HSA-166016 Reactome Name: Toll Like Receptor 4 (TLR4) Cascade See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-983169 R-HSA-983169 Reactome Name: Class I MHC mediated antigen processing & presentation See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome R-HSA-168179 R-HSA-168179 Reactome Name: Toll Like Receptor TLR1:TLR2 Cascade See in Reactome R-HSA-422356 R-HSA-422356 Reactome Name: Regulation of insulin secretion See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-2173782 R-HSA-2173782 Reactome Name: Binding and Uptake of Ligands by Scavenger Receptors See in Reactome	Immune System Metabolism Developmental Biology Vesicle-mediated transport Hemostasis	R-HSA-1236956 ( R-HSA-1236973 ) R-HSA-1236956 Reaction Name: Engulfment of particulate antigen into phagocytic vesicle See in Reactome R-HSA-1236958 ( R-HSA-1236973 ) R-HSA-1236958 Reaction Name: Interaction of particulate antigens with dendritic cell receptors See in Reactome R-HSA-166072 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166072 Reaction Name: MyD88 forms a complex with TIRAP:activated TLR2/4 See in Reactome R-HSA-166082 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166082 Reaction Name: IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex See in Reactome R-HSA-166091 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166091 Reaction Name: IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex See in Reactome R-HSA-166119 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166119 Reaction Name: First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal See in Reactome R-HSA-166284 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166284 Reaction Name: Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP See in Reactome R-HSA-166286 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166286 Reaction Name: Multiple IRAK1 autophosphorylation steps See in Reactome R-HSA-166362 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166362 Reaction Name: Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex See in Reactome R-HSA-166363 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166363 Reaction Name: TRAF6 binds to hp- IRAK1 See in Reactome R-HSA-168950 ( R-HSA-168188 ) R-HSA-168950 Reaction Name: TLR6:TLR2 is recruited to ligand:CD14:CD36 See in Reactome R-HSA-2187264 ( R-HSA-3000471 ) R-HSA-2187264 Reaction Name: Platelet glycoprotein IV (CD36) binds ligands See in Reactome R-HSA-2201316 ( R-HSA-166058; R-HSA-168188 ) R-HSA-2201316 Reaction Name: Activated TLR2/4 interacts with MAL (TIRAP) See in Reactome R-HSA-2201322 ( R-HSA-166058; R-HSA-168188 ) R-HSA-2201322 Reaction Name: TIRAP is phosphorylated by BTK See in Reactome R-HSA-2247512 ( R-HSA-3000471 ) R-HSA-2247512 Reaction Name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed See in Reactome R-HSA-2262775 ( R-HSA-166058; R-HSA-168188 ) R-HSA-2262775 Reaction Name: Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex See in Reactome R-HSA-2262777 ( R-HSA-166058; R-HSA-168188 ) R-HSA-2262777 Reaction Name: TRAF6 binds to p-IRAK2 See in Reactome R-HSA-2559414 ( R-HSA-166058; R-HSA-168188 ) R-HSA-2559414 Reaction Name: Activated TLR2/4:TIRAP interacts with BTK See in Reactome R-HSA-2559464 ( R-HSA-168188 ) R-HSA-2559464 Reaction Name: TLR6/2 ligand associates with CD14 and CD36 within lipid rafts See in Reactome R-HSA-434381 ( R-HSA-434313 ) R-HSA-434381 Reaction Name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol See in Reactome R-HSA-481044 ( R-HSA-114608 ) R-HSA-481044 Reaction Name: Surface deployment of platelet alpha granule membrane components See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-6797267 ( R-HSA-6785807 ) R-HSA-6797267 Reaction Name: Expression of CD36 See in Reactome R-HSA-6799350 ( R-HSA-6798695 ) R-HSA-6799350 Reaction Name: Exocytosis of specific granule membrane proteins See in Reactome R-HSA-8863895 ( R-HSA-1236974 ) R-HSA-8863895 Reaction Name: IKKB phosphorylates SNAP23 See in Reactome R-HSA-8869667 ( R-HSA-5686938 ) R-HSA-8869667 Reaction Name: oxLDL:CD36 binds TLR4:TLR6 See in Reactome R-HSA-937022 ( R-HSA-166058; R-HSA-168188 ) R-HSA-937022 Reaction Name: IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP See in Reactome R-HSA-937059 ( R-HSA-166058; R-HSA-168188 ) R-HSA-937059 Reaction Name: Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex See in Reactome R-HSA-937079 ( R-HSA-166058; R-HSA-168188 ) R-HSA-937079 Reaction Name: MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 See in Reactome
MONDO:0012183	CDK4	P11802	2.7.11.22	R-HSA-2559585 R-HSA-2559585 Reactome Name: Oncogene Induced Senescence See in Reactome R-HSA-2559580 R-HSA-2559580 Reactome Name: Oxidative Stress Induced Senescence See in Reactome R-HSA-2559582 R-HSA-2559582 Reactome Name: Senescence-Associated Secretory Phenotype (SASP) See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-912446 R-HSA-912446 Reactome Name: Meiotic recombination See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-8849470 R-HSA-8849470 Reactome Name: PTK6 Regulates Cell Cycle See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-75815 R-HSA-75815 Reactome Name: Ubiquitin-dependent degradation of Cyclin D See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-187577 R-HSA-187577 Reactome Name: SCF(Skp2)-mediated degradation of p27/p21 See in Reactome	R-HSA-8848021 R-HSA-8848021 Reactome Name: Signaling by PTK6 See in Reactome R-HSA-2559583 R-HSA-2559583 Reactome Name: Cellular Senescence See in Reactome R-HSA-9006927 R-HSA-9006927 Reactome Name: Signaling by Non-Receptor Tyrosine Kinases See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1474165 R-HSA-1474165 Reactome Name: Reproduction See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-69656 R-HSA-69656 Reactome Name: Cyclin A:Cdk2-associated events at S phase entry See in Reactome R-HSA-69206 R-HSA-69206 Reactome Name: G1/S Transition See in Reactome R-HSA-69202 R-HSA-69202 Reactome Name: Cyclin E associated events during G1/S transition See in Reactome R-HSA-69242 R-HSA-69242 Reactome Name: S Phase See in Reactome R-HSA-1500620 R-HSA-1500620 Reactome Name: Meiosis See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction	R-HSA-1226094 ( R-HSA-69231 ) R-HSA-1226094 Reaction Name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex See in Reactome R-HSA-1226095 ( R-HSA-69231 ) R-HSA-1226095 Reaction Name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex See in Reactome R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-182594 Reaction Name: Association of INK4 family proteins with CDK4/6 See in Reactome R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215385 Reaction Name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 See in Reactome R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-3215426 Reaction Name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 See in Reactome R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-5216234 Reaction Name: PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-5661117 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 See in Reactome R-HSA-69227 ( R-HSA-69231 ) R-HSA-69227 Reaction Name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-75820 ( R-HSA-75815 ) R-HSA-75820 Reaction Name: Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta See in Reactome R-HSA-75822 ( R-HSA-75815 ) R-HSA-75822 Reaction Name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm See in Reactome R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848414 Reaction Name: Activated PTK6 binds CDKN1B See in Reactome R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 Reaction Name: PTK6 phosphorylates CDKN1B See in Reactome R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941895 Reaction Name: Formation of CDK4/6:CCND complexes See in Reactome R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8941915 Reaction Name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes See in Reactome R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942607 Reaction Name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes See in Reactome R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942803 Reaction Name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus See in Reactome R-HSA-8942836 ( R-HSA-69231 ) R-HSA-8942836 Reaction Name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 See in Reactome R-HSA-9008412 ( R-HSA-212436; R-HSA-8878166 ) R-HSA-9008412 Reaction Name: CDK4 phosphorylates RUNX2 See in Reactome R-HSA-9018017 ( R-HSA-69231 ) R-HSA-9018017 Reaction Name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-912429 ( R-HSA-912446 ) R-HSA-912429 Reaction Name: Resolution of meiotic holliday junction See in Reactome R-HSA-912458 ( R-HSA-912446 ) R-HSA-912458 Reaction Name: Formation of meiotic heteroduplex See in Reactome R-HSA-912496 ( R-HSA-912446 ) R-HSA-912496 Reaction Name: Formation of meiotic holliday junction See in Reactome R-HSA-912503 ( R-HSA-912446 ) R-HSA-912503 Reaction Name: Formation of meiotic single-stranded DNA invasion complex See in Reactome R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9624112 Reaction Name: CEBPA binds CDK4 See in Reactome R-HSA-9754130 ( R-HSA-69231 ) R-HSA-9754130 Reaction Name: CDK4 inhibitors bind CDK4 See in Reactome
MONDO:0012585	CD36	P16671	-	R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-168188 R-HSA-168188 Reactome Name: Toll Like Receptor TLR6:TLR2 Cascade See in Reactome R-HSA-434313 R-HSA-434313 Reactome Name: Intracellular metabolism of fatty acids regulates insulin secretion See in Reactome R-HSA-114608 R-HSA-114608 Reactome Name: Platelet degranulation See in Reactome R-HSA-1236973 R-HSA-1236973 Reactome Name: Cross-presentation of particulate exogenous antigens (phagosomes) See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-1236974 R-HSA-1236974 Reactome Name: ER-Phagosome pathway See in Reactome R-HSA-3000471 R-HSA-3000471 Reactome Name: Scavenging by Class B Receptors See in Reactome R-HSA-166058 R-HSA-166058 Reactome Name: MyD88:MAL(TIRAP) cascade initiated on plasma membrane See in Reactome R-HSA-6785807 R-HSA-6785807 Reactome Name: Interleukin-4 and Interleukin-13 signaling See in Reactome R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-5686938 R-HSA-5686938 Reactome Name: Regulation of TLR by endogenous ligand See in Reactome	R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-400451 R-HSA-400451 Reactome Name: Free fatty acids regulate insulin secretion See in Reactome R-HSA-181438 R-HSA-181438 Reactome Name: Toll Like Receptor 2 (TLR2) Cascade See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome R-HSA-1236975 R-HSA-1236975 Reactome Name: Antigen processing-Cross presentation See in Reactome R-HSA-76005 R-HSA-76005 Reactome Name: Response to elevated platelet cytosolic Ca2+ See in Reactome R-HSA-168898 R-HSA-168898 Reactome Name: Toll-like Receptor Cascades See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-166016 R-HSA-166016 Reactome Name: Toll Like Receptor 4 (TLR4) Cascade See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-983169 R-HSA-983169 Reactome Name: Class I MHC mediated antigen processing & presentation See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome R-HSA-168179 R-HSA-168179 Reactome Name: Toll Like Receptor TLR1:TLR2 Cascade See in Reactome R-HSA-422356 R-HSA-422356 Reactome Name: Regulation of insulin secretion See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-2173782 R-HSA-2173782 Reactome Name: Binding and Uptake of Ligands by Scavenger Receptors See in Reactome	Immune System Metabolism Developmental Biology Vesicle-mediated transport Hemostasis	R-HSA-1236956 ( R-HSA-1236973 ) R-HSA-1236956 Reaction Name: Engulfment of particulate antigen into phagocytic vesicle See in Reactome R-HSA-1236958 ( R-HSA-1236973 ) R-HSA-1236958 Reaction Name: Interaction of particulate antigens with dendritic cell receptors See in Reactome R-HSA-166072 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166072 Reaction Name: MyD88 forms a complex with TIRAP:activated TLR2/4 See in Reactome R-HSA-166082 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166082 Reaction Name: IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex See in Reactome R-HSA-166091 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166091 Reaction Name: IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex See in Reactome R-HSA-166119 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166119 Reaction Name: First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal See in Reactome R-HSA-166284 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166284 Reaction Name: Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP See in Reactome R-HSA-166286 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166286 Reaction Name: Multiple IRAK1 autophosphorylation steps See in Reactome R-HSA-166362 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166362 Reaction Name: Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex See in Reactome R-HSA-166363 ( R-HSA-166058; R-HSA-168188 ) R-HSA-166363 Reaction Name: TRAF6 binds to hp- IRAK1 See in Reactome R-HSA-168950 ( R-HSA-168188 ) R-HSA-168950 Reaction Name: TLR6:TLR2 is recruited to ligand:CD14:CD36 See in Reactome R-HSA-2187264 ( R-HSA-3000471 ) R-HSA-2187264 Reaction Name: Platelet glycoprotein IV (CD36) binds ligands See in Reactome R-HSA-2201316 ( R-HSA-166058; R-HSA-168188 ) R-HSA-2201316 Reaction Name: Activated TLR2/4 interacts with MAL (TIRAP) See in Reactome R-HSA-2201322 ( R-HSA-166058; R-HSA-168188 ) R-HSA-2201322 Reaction Name: TIRAP is phosphorylated by BTK See in Reactome R-HSA-2247512 ( R-HSA-3000471 ) R-HSA-2247512 Reaction Name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed See in Reactome R-HSA-2262775 ( R-HSA-166058; R-HSA-168188 ) R-HSA-2262775 Reaction Name: Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex See in Reactome R-HSA-2262777 ( R-HSA-166058; R-HSA-168188 ) R-HSA-2262777 Reaction Name: TRAF6 binds to p-IRAK2 See in Reactome R-HSA-2559414 ( R-HSA-166058; R-HSA-168188 ) R-HSA-2559414 Reaction Name: Activated TLR2/4:TIRAP interacts with BTK See in Reactome R-HSA-2559464 ( R-HSA-168188 ) R-HSA-2559464 Reaction Name: TLR6/2 ligand associates with CD14 and CD36 within lipid rafts See in Reactome R-HSA-434381 ( R-HSA-434313 ) R-HSA-434381 Reaction Name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol See in Reactome R-HSA-481044 ( R-HSA-114608 ) R-HSA-481044 Reaction Name: Surface deployment of platelet alpha granule membrane components See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-6797267 ( R-HSA-6785807 ) R-HSA-6797267 Reaction Name: Expression of CD36 See in Reactome R-HSA-6799350 ( R-HSA-6798695 ) R-HSA-6799350 Reaction Name: Exocytosis of specific granule membrane proteins See in Reactome R-HSA-8863895 ( R-HSA-1236974 ) R-HSA-8863895 Reaction Name: IKKB phosphorylates SNAP23 See in Reactome R-HSA-8869667 ( R-HSA-5686938 ) R-HSA-8869667 Reaction Name: oxLDL:CD36 binds TLR4:TLR6 See in Reactome R-HSA-937022 ( R-HSA-166058; R-HSA-168188 ) R-HSA-937022 Reaction Name: IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP See in Reactome R-HSA-937059 ( R-HSA-166058; R-HSA-168188 ) R-HSA-937059 Reaction Name: Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex See in Reactome R-HSA-937079 ( R-HSA-166058; R-HSA-168188 ) R-HSA-937079 Reaction Name: MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88 See in Reactome
MONDO:0013364	EP300	Q09472	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-5689901 R-HSA-5689901 Reactome Name: Metalloprotease DUBs See in Reactome R-HSA-6804760 R-HSA-6804760 Reactome Name: Regulation of TP53 Activity through Methylation See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-6782135 R-HSA-6782135 Reactome Name: Dual incision in TC-NER See in Reactome R-HSA-6782210 R-HSA-6782210 Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-6804114 R-HSA-6804114 Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-6781827 R-HSA-6781827 Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER) See in Reactome R-HSA-156711 R-HSA-156711 Reactome Name: Polo-like kinase mediated events See in Reactome R-HSA-5250924 R-HSA-5250924 Reactome Name: B-WICH complex positively regulates rRNA expression See in Reactome R-HSA-6781823 R-HSA-6781823 Reactome Name: Formation of TC-NER Pre-Incision Complex See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-9701898 R-HSA-9701898 Reactome Name: STAT3 nuclear events downstream of ALK signaling See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8936459 R-HSA-8936459 Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2197563 R-HSA-2197563 Reactome Name: NOTCH2 intracellular domain regulates transcription See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8951936 R-HSA-8951936 Reactome Name: RUNX3 regulates p14-ARF See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-6811555 R-HSA-6811555 Reactome Name: PI5P Regulates TP53 Acetylation See in Reactome R-HSA-6804758 R-HSA-6804758 Reactome Name: Regulation of TP53 Activity through Acetylation See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-6791312 R-HSA-6791312 Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-5696398 R-HSA-5696398 Reactome Name: Nucleotide Excision Repair See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-1980145 R-HSA-1980145 Reactome Name: Signaling by NOTCH2 See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-5250913 R-HSA-5250913 Reactome Name: Positive epigenetic regulation of rRNA expression See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome	Circadian Clock Immune System Cell Cycle Developmental Biology Metabolism Gene expression (Transcription) DNA Repair Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-6782069 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782069 Reaction Name: UVSSA:USP7 deubiquitinates ERCC6 See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome R-HSA-9011981 ( R-HSA-9018519 ) R-HSA-9011981 Reaction Name: EP300 is recruited to MYC and BCL2 genes See in Reactome R-HSA-8878050 ( R-HSA-8939243 ) R-HSA-8878050 Reaction Name: HIPK2 phosphorylates RUNX1 and EP300 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-8952101 ( R-HSA-8951936 ) R-HSA-8952101 Reaction Name: p14-ARF transcription is stimulated by RUNX proteins See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9038163 ( R-HSA-9018519 ) R-HSA-9038163 Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-6782211 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782211 Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-9613451 ( R-HSA-9031628 ) R-HSA-9613451 Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes See in Reactome R-HSA-8936621 ( R-HSA-8936459 ) R-HSA-8936621 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter See in Reactome R-HSA-5628871 ( R-HSA-6804758 ) R-HSA-5628871 Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9620723 ( R-HSA-9031628 ) R-HSA-9620723 Reaction Name: VGF gene expression See in Reactome R-HSA-5250938 ( R-HSA-5250924 ) R-HSA-5250938 Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 See in Reactome R-HSA-6782204 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782204 Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER See in Reactome R-HSA-5617867 ( R-HSA-5617472 ) R-HSA-5617867 Reaction Name: HOXB4 gene is transcribed See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-9023884 ( R-HSA-9018519 ) R-HSA-9023884 Reaction Name: NCOA1 recruits EP300 to TGFA promoter See in Reactome R-HSA-8937050 ( R-HSA-8936459 ) R-HSA-8937050 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter See in Reactome R-HSA-8952081 ( R-HSA-8951936 ) R-HSA-8952081 Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus See in Reactome R-HSA-3662335 ( R-HSA-3214847 ) R-HSA-3662335 Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4 See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-6804379 ( R-HSA-6804760 ) R-HSA-6804379 Reaction Name: PRMT5 binds TTC5 See in Reactome R-HSA-4088162 ( R-HSA-156711 ) R-HSA-4088162 Reaction Name: FOXM1 binds CDC25A promoter See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-9023846 ( R-HSA-9018519 ) R-HSA-9023846 Reaction Name: Estrogen-responsive CTSD expression See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-9008315 ( R-HSA-9018519 ) R-HSA-9008315 Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen See in Reactome R-HSA-8936628 ( R-HSA-8936459 ) R-HSA-8936628 Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9023860 ( R-HSA-9018519 ) R-HSA-9023860 Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-8936481 ( R-HSA-8936459 ) R-HSA-8936481 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter See in Reactome R-HSA-5663264 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663264 Reaction Name: RORA, EP300 bind CPT1A gene See in Reactome R-HSA-6805650 ( R-HSA-6804758 ) R-HSA-6805650 Reaction Name: MTA2-NuRD complex deacetylates TP53 See in Reactome R-HSA-5617452 ( R-HSA-5617472 ) R-HSA-5617452 Reaction Name: Retinoic acid activates HOXB1 chromatin See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-9613460 ( R-HSA-9031628 ) R-HSA-9613460 Reaction Name: ID1 and ID3 gene expression See in Reactome R-HSA-9620717 ( R-HSA-9031628 ) R-HSA-9620717 Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter See in Reactome R-HSA-8951951 ( R-HSA-8951936 ) R-HSA-8951951 Reaction Name: RUNX3 binds EP300 See in Reactome R-HSA-9029561 ( R-HSA-9029569 ) R-HSA-9029561 Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-9617064 ( R-HSA-9616222 ) R-HSA-9617064 Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene See in Reactome R-HSA-9008285 ( R-HSA-9018519 ) R-HSA-9008285 Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-9701531 ( R-HSA-9701898 ) R-HSA-9701531 Reaction Name: p-Y705,S727 STAT3 is acetylated See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-8937097 ( R-HSA-8936459 ) R-HSA-8937097 Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-8936616 ( R-HSA-8936459 ) R-HSA-8936616 Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene See in Reactome R-HSA-5663246 ( R-HSA-400253 ) R-HSA-5663246 Reaction Name: RORA, EP300 bind NPAS2 gene See in Reactome R-HSA-6804229 ( R-HSA-6804760 ) R-HSA-6804229 Reaction Name: JMY, TTC5 and EP300 bind See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-8878056 ( R-HSA-8939243 ) R-HSA-8878056 Reaction Name: RUNX1:CBFB binds EP300 See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-6782004 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782004 Reaction Name: Assembly of the pre-incision complex in TC-NER See in Reactome R-HSA-5250930 ( R-HSA-5250924 ) R-HSA-5250930 Reaction Name: B-WICH recruits histone acetyltransferases See in Reactome R-HSA-8937016 ( R-HSA-8936459 ) R-HSA-8937016 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter See in Reactome R-HSA-400342 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-400342 Reaction Name: Expression of ARNTL (BMAL1) See in Reactome R-HSA-6782138 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782138 Reaction Name: ERCC5 and RPA bind TC-NER site See in Reactome R-HSA-5617859 ( R-HSA-5617472 ) R-HSA-5617859 Reaction Name: Retinoic acid activates HOXB4 chromatin See in Reactome R-HSA-8952058 ( R-HSA-8951936 ) R-HSA-8952058 Reaction Name: CCND1 binds RUNX3 and displaces EP300 See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-9620515 ( R-HSA-9617629 ) R-HSA-9620515 Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-5693644 ( R-HSA-5617472 ) R-HSA-5693644 Reaction Name: HOXB1 maintains activation of HOXB1 chromatin See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-5617862 ( R-HSA-5617472 ) R-HSA-5617862 Reaction Name: Retinoic acid activates HOXA4 chromatin See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-8935731 ( R-HSA-8936459 ) R-HSA-8935731 Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-6782208 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782208 Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER See in Reactome R-HSA-5663293 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663293 Reaction Name: RORA, EP300 bind SREBF1 gene See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-549475 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-549475 Reaction Name: Expression of NR1D1 (REV-ERBA) See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-6782227 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782227 Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER See in Reactome R-HSA-6811508 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811508 Reaction Name: ING2-bound EP300 acetylates TP53 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-8951977 ( R-HSA-8951936 ) R-HSA-8951977 Reaction Name: Acetylated RUNX3 binds to BRD2 See in Reactome R-HSA-9023840 ( R-HSA-9018519 ) R-HSA-9023840 Reaction Name: HATs and coactivators are recruited to the CTSD gene See in Reactome R-HSA-6811479 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811479 Reaction Name: ING2 recruits EP300 to TP53 See in Reactome R-HSA-5617877 ( R-HSA-5617472 ) R-HSA-5617877 Reaction Name: HOXA4 gene is transcribed See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-6804383 ( R-HSA-6804760 ) R-HSA-6804383 Reaction Name: PRMT5 methylates TP53 See in Reactome R-HSA-6782234 ( R-HSA-6781827 ) R-HSA-6782234 Reaction Name: Recovery of RNA synthesis after TC-NER See in Reactome R-HSA-9011975 ( R-HSA-9018519 ) R-HSA-9011975 Reaction Name: Estrogen-responsive MYC gene expression See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-2976551 ( R-HSA-2197563 ) R-HSA-2976551 Reaction Name: NOTCH2 stimulates GZMB transcription See in Reactome R-HSA-1368081 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-1368081 Reaction Name: Expression of SREBF1 (SREBP1) See in Reactome R-HSA-5617431 ( R-HSA-5617472 ) R-HSA-5617431 Reaction Name: Retinoic acid activates HOXA1 chromatin See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-3215152 ( R-HSA-6804114 ) R-HSA-3215152 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter See in Reactome R-HSA-4088152 ( R-HSA-156711 ) R-HSA-4088152 Reaction Name: FOXM1 stimulates CDC25A transcription See in Reactome R-HSA-9009371 ( R-HSA-9018519 ) R-HSA-9009371 Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter See in Reactome R-HSA-9023859 ( R-HSA-9018519 ) R-HSA-9023859 Reaction Name: Estrogen-responsive TFF1 gene expression See in Reactome R-HSA-1368087 ( R-HSA-400253 ) R-HSA-1368087 Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-3899291 ( R-HSA-3899300 ) R-HSA-3899291 Reaction Name: SUMOylation of EP300 with SUMO1 See in Reactome R-HSA-9634433 ( R-HSA-9616222 ) R-HSA-9634433 Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid See in Reactome R-HSA-9605057 ( R-HSA-9029569 ) R-HSA-9605057 Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 See in Reactome R-HSA-5617471 ( R-HSA-5617472 ) R-HSA-5617471 Reaction Name: HOXA1 gene is transcribed See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-5691381 ( R-HSA-5689901 ) R-HSA-5691381 Reaction Name: MYSM1 deubiquitinates Histone H2A See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9018499 ( R-HSA-9018519 ) R-HSA-9018499 Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-6782131 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782131 Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-8935740 ( R-HSA-8936459 ) R-HSA-8935740 Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene See in Reactome R-HSA-9009378 ( R-HSA-9018519 ) R-HSA-9009378 Reaction Name: Estrogen-responsive CCND1 gene expression See in Reactome R-HSA-8952419 ( R-HSA-8941858 ) R-HSA-8952419 Reaction Name: SMURFs ubiquitinate RUNX3 See in Reactome R-HSA-6782224 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782224 Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER See in Reactome R-HSA-8936979 ( R-HSA-8936459 ) R-HSA-8936979 Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-3215144 ( R-HSA-6804114 ) R-HSA-3215144 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription See in Reactome R-HSA-8951966 ( R-HSA-8951936 ) R-HSA-8951966 Reaction Name: EP300 acetylates RUNX3 See in Reactome R-HSA-9008271 ( R-HSA-9018519 ) R-HSA-9008271 Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter See in Reactome R-HSA-9011941 ( R-HSA-9018519 ) R-HSA-9011941 Reaction Name: Estrogen-responsive BCL2 gene expression See in Reactome R-HSA-2976563 ( R-HSA-2197563 ) R-HSA-2976563 Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter See in Reactome R-HSA-5663273 ( R-HSA-400253 ) R-HSA-5663273 Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-6782141 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782141 Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-8937037 ( R-HSA-8936459 ) R-HSA-8937037 Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-9617735 ( R-HSA-9617629 ) R-HSA-9617735 Reaction Name: TXN disrupts FOXO4 complex with EP300 See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-9018497 ( R-HSA-9018519 ) R-HSA-9018497 Reaction Name: Estrogen-responsive TFF3 gene expression See in Reactome R-HSA-8936995 ( R-HSA-8936459 ) R-HSA-8936995 Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9684118 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-9684118 Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-6804242 ( R-HSA-6804760 ) R-HSA-6804242 Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5 See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-3222093 ( R-HSA-6804758 ) R-HSA-3222093 Reaction Name: BRD7 binds TP53 and EP300 See in Reactome
MONDO:0015356	CDK4	P11802	2.7.11.22	R-HSA-2559585 R-HSA-2559585 Reactome Name: Oncogene Induced Senescence See in Reactome R-HSA-2559580 R-HSA-2559580 Reactome Name: Oxidative Stress Induced Senescence See in Reactome R-HSA-2559582 R-HSA-2559582 Reactome Name: Senescence-Associated Secretory Phenotype (SASP) See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-912446 R-HSA-912446 Reactome Name: Meiotic recombination See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-8849470 R-HSA-8849470 Reactome Name: PTK6 Regulates Cell Cycle See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-75815 R-HSA-75815 Reactome Name: Ubiquitin-dependent degradation of Cyclin D See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-187577 R-HSA-187577 Reactome Name: SCF(Skp2)-mediated degradation of p27/p21 See in Reactome	R-HSA-8848021 R-HSA-8848021 Reactome Name: Signaling by PTK6 See in Reactome R-HSA-2559583 R-HSA-2559583 Reactome Name: Cellular Senescence See in Reactome R-HSA-9006927 R-HSA-9006927 Reactome Name: Signaling by Non-Receptor Tyrosine Kinases See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1474165 R-HSA-1474165 Reactome Name: Reproduction See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-69656 R-HSA-69656 Reactome Name: Cyclin A:Cdk2-associated events at S phase entry See in Reactome R-HSA-69206 R-HSA-69206 Reactome Name: G1/S Transition See in Reactome R-HSA-69202 R-HSA-69202 Reactome Name: Cyclin E associated events during G1/S transition See in Reactome R-HSA-69242 R-HSA-69242 Reactome Name: S Phase See in Reactome R-HSA-1500620 R-HSA-1500620 Reactome Name: Meiosis See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction	R-HSA-1226094 ( R-HSA-69231 ) R-HSA-1226094 Reaction Name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex See in Reactome R-HSA-1226095 ( R-HSA-69231 ) R-HSA-1226095 Reaction Name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex See in Reactome R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-182594 Reaction Name: Association of INK4 family proteins with CDK4/6 See in Reactome R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215385 Reaction Name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 See in Reactome R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-3215426 Reaction Name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 See in Reactome R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-5216234 Reaction Name: PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-5661117 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 See in Reactome R-HSA-69227 ( R-HSA-69231 ) R-HSA-69227 Reaction Name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-75820 ( R-HSA-75815 ) R-HSA-75820 Reaction Name: Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta See in Reactome R-HSA-75822 ( R-HSA-75815 ) R-HSA-75822 Reaction Name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm See in Reactome R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848414 Reaction Name: Activated PTK6 binds CDKN1B See in Reactome R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 Reaction Name: PTK6 phosphorylates CDKN1B See in Reactome R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941895 Reaction Name: Formation of CDK4/6:CCND complexes See in Reactome R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8941915 Reaction Name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes See in Reactome R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942607 Reaction Name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes See in Reactome R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942803 Reaction Name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus See in Reactome R-HSA-8942836 ( R-HSA-69231 ) R-HSA-8942836 Reaction Name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 See in Reactome R-HSA-9008412 ( R-HSA-212436; R-HSA-8878166 ) R-HSA-9008412 Reaction Name: CDK4 phosphorylates RUNX2 See in Reactome R-HSA-9018017 ( R-HSA-69231 ) R-HSA-9018017 Reaction Name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-912429 ( R-HSA-912446 ) R-HSA-912429 Reaction Name: Resolution of meiotic holliday junction See in Reactome R-HSA-912458 ( R-HSA-912446 ) R-HSA-912458 Reaction Name: Formation of meiotic heteroduplex See in Reactome R-HSA-912496 ( R-HSA-912446 ) R-HSA-912496 Reaction Name: Formation of meiotic holliday junction See in Reactome R-HSA-912503 ( R-HSA-912446 ) R-HSA-912503 Reaction Name: Formation of meiotic single-stranded DNA invasion complex See in Reactome R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9624112 Reaction Name: CEBPA binds CDK4 See in Reactome R-HSA-9754130 ( R-HSA-69231 ) R-HSA-9754130 Reaction Name: CDK4 inhibitors bind CDK4 See in Reactome
MONDO:0018614	CDK19	Q9BWU1	2.7.11.22	R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Metabolism Developmental Biology	R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome
MONDO:0019086	EP300	Q09472	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-5689901 R-HSA-5689901 Reactome Name: Metalloprotease DUBs See in Reactome R-HSA-6804760 R-HSA-6804760 Reactome Name: Regulation of TP53 Activity through Methylation See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-6782135 R-HSA-6782135 Reactome Name: Dual incision in TC-NER See in Reactome R-HSA-6782210 R-HSA-6782210 Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-6804114 R-HSA-6804114 Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-6781827 R-HSA-6781827 Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER) See in Reactome R-HSA-156711 R-HSA-156711 Reactome Name: Polo-like kinase mediated events See in Reactome R-HSA-5250924 R-HSA-5250924 Reactome Name: B-WICH complex positively regulates rRNA expression See in Reactome R-HSA-6781823 R-HSA-6781823 Reactome Name: Formation of TC-NER Pre-Incision Complex See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-9701898 R-HSA-9701898 Reactome Name: STAT3 nuclear events downstream of ALK signaling See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8936459 R-HSA-8936459 Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2197563 R-HSA-2197563 Reactome Name: NOTCH2 intracellular domain regulates transcription See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8951936 R-HSA-8951936 Reactome Name: RUNX3 regulates p14-ARF See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-6811555 R-HSA-6811555 Reactome Name: PI5P Regulates TP53 Acetylation See in Reactome R-HSA-6804758 R-HSA-6804758 Reactome Name: Regulation of TP53 Activity through Acetylation See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-6791312 R-HSA-6791312 Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-5696398 R-HSA-5696398 Reactome Name: Nucleotide Excision Repair See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-1980145 R-HSA-1980145 Reactome Name: Signaling by NOTCH2 See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-5250913 R-HSA-5250913 Reactome Name: Positive epigenetic regulation of rRNA expression See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome	Circadian Clock Immune System Cell Cycle Developmental Biology Metabolism Gene expression (Transcription) DNA Repair Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-6782069 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782069 Reaction Name: UVSSA:USP7 deubiquitinates ERCC6 See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome R-HSA-9011981 ( R-HSA-9018519 ) R-HSA-9011981 Reaction Name: EP300 is recruited to MYC and BCL2 genes See in Reactome R-HSA-8878050 ( R-HSA-8939243 ) R-HSA-8878050 Reaction Name: HIPK2 phosphorylates RUNX1 and EP300 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-8952101 ( R-HSA-8951936 ) R-HSA-8952101 Reaction Name: p14-ARF transcription is stimulated by RUNX proteins See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9038163 ( R-HSA-9018519 ) R-HSA-9038163 Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-6782211 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782211 Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-9613451 ( R-HSA-9031628 ) R-HSA-9613451 Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes See in Reactome R-HSA-8936621 ( R-HSA-8936459 ) R-HSA-8936621 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter See in Reactome R-HSA-5628871 ( R-HSA-6804758 ) R-HSA-5628871 Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9620723 ( R-HSA-9031628 ) R-HSA-9620723 Reaction Name: VGF gene expression See in Reactome R-HSA-5250938 ( R-HSA-5250924 ) R-HSA-5250938 Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 See in Reactome R-HSA-6782204 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782204 Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER See in Reactome R-HSA-5617867 ( R-HSA-5617472 ) R-HSA-5617867 Reaction Name: HOXB4 gene is transcribed See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-9023884 ( R-HSA-9018519 ) R-HSA-9023884 Reaction Name: NCOA1 recruits EP300 to TGFA promoter See in Reactome R-HSA-8937050 ( R-HSA-8936459 ) R-HSA-8937050 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter See in Reactome R-HSA-8952081 ( R-HSA-8951936 ) R-HSA-8952081 Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus See in Reactome R-HSA-3662335 ( R-HSA-3214847 ) R-HSA-3662335 Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4 See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-6804379 ( R-HSA-6804760 ) R-HSA-6804379 Reaction Name: PRMT5 binds TTC5 See in Reactome R-HSA-4088162 ( R-HSA-156711 ) R-HSA-4088162 Reaction Name: FOXM1 binds CDC25A promoter See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-9023846 ( R-HSA-9018519 ) R-HSA-9023846 Reaction Name: Estrogen-responsive CTSD expression See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-9008315 ( R-HSA-9018519 ) R-HSA-9008315 Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen See in Reactome R-HSA-8936628 ( R-HSA-8936459 ) R-HSA-8936628 Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9023860 ( R-HSA-9018519 ) R-HSA-9023860 Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-8936481 ( R-HSA-8936459 ) R-HSA-8936481 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter See in Reactome R-HSA-5663264 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663264 Reaction Name: RORA, EP300 bind CPT1A gene See in Reactome R-HSA-6805650 ( R-HSA-6804758 ) R-HSA-6805650 Reaction Name: MTA2-NuRD complex deacetylates TP53 See in Reactome R-HSA-5617452 ( R-HSA-5617472 ) R-HSA-5617452 Reaction Name: Retinoic acid activates HOXB1 chromatin See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-9613460 ( R-HSA-9031628 ) R-HSA-9613460 Reaction Name: ID1 and ID3 gene expression See in Reactome R-HSA-9620717 ( R-HSA-9031628 ) R-HSA-9620717 Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter See in Reactome R-HSA-8951951 ( R-HSA-8951936 ) R-HSA-8951951 Reaction Name: RUNX3 binds EP300 See in Reactome R-HSA-9029561 ( R-HSA-9029569 ) R-HSA-9029561 Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-9617064 ( R-HSA-9616222 ) R-HSA-9617064 Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene See in Reactome R-HSA-9008285 ( R-HSA-9018519 ) R-HSA-9008285 Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-9701531 ( R-HSA-9701898 ) R-HSA-9701531 Reaction Name: p-Y705,S727 STAT3 is acetylated See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-8937097 ( R-HSA-8936459 ) R-HSA-8937097 Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-8936616 ( R-HSA-8936459 ) R-HSA-8936616 Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene See in Reactome R-HSA-5663246 ( R-HSA-400253 ) R-HSA-5663246 Reaction Name: RORA, EP300 bind NPAS2 gene See in Reactome R-HSA-6804229 ( R-HSA-6804760 ) R-HSA-6804229 Reaction Name: JMY, TTC5 and EP300 bind See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-8878056 ( R-HSA-8939243 ) R-HSA-8878056 Reaction Name: RUNX1:CBFB binds EP300 See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-6782004 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782004 Reaction Name: Assembly of the pre-incision complex in TC-NER See in Reactome R-HSA-5250930 ( R-HSA-5250924 ) R-HSA-5250930 Reaction Name: B-WICH recruits histone acetyltransferases See in Reactome R-HSA-8937016 ( R-HSA-8936459 ) R-HSA-8937016 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter See in Reactome R-HSA-400342 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-400342 Reaction Name: Expression of ARNTL (BMAL1) See in Reactome R-HSA-6782138 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782138 Reaction Name: ERCC5 and RPA bind TC-NER site See in Reactome R-HSA-5617859 ( R-HSA-5617472 ) R-HSA-5617859 Reaction Name: Retinoic acid activates HOXB4 chromatin See in Reactome R-HSA-8952058 ( R-HSA-8951936 ) R-HSA-8952058 Reaction Name: CCND1 binds RUNX3 and displaces EP300 See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-9620515 ( R-HSA-9617629 ) R-HSA-9620515 Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-5693644 ( R-HSA-5617472 ) R-HSA-5693644 Reaction Name: HOXB1 maintains activation of HOXB1 chromatin See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-5617862 ( R-HSA-5617472 ) R-HSA-5617862 Reaction Name: Retinoic acid activates HOXA4 chromatin See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-8935731 ( R-HSA-8936459 ) R-HSA-8935731 Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-6782208 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782208 Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER See in Reactome R-HSA-5663293 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663293 Reaction Name: RORA, EP300 bind SREBF1 gene See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-549475 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-549475 Reaction Name: Expression of NR1D1 (REV-ERBA) See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-6782227 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782227 Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER See in Reactome R-HSA-6811508 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811508 Reaction Name: ING2-bound EP300 acetylates TP53 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-8951977 ( R-HSA-8951936 ) R-HSA-8951977 Reaction Name: Acetylated RUNX3 binds to BRD2 See in Reactome R-HSA-9023840 ( R-HSA-9018519 ) R-HSA-9023840 Reaction Name: HATs and coactivators are recruited to the CTSD gene See in Reactome R-HSA-6811479 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811479 Reaction Name: ING2 recruits EP300 to TP53 See in Reactome R-HSA-5617877 ( R-HSA-5617472 ) R-HSA-5617877 Reaction Name: HOXA4 gene is transcribed See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-6804383 ( R-HSA-6804760 ) R-HSA-6804383 Reaction Name: PRMT5 methylates TP53 See in Reactome R-HSA-6782234 ( R-HSA-6781827 ) R-HSA-6782234 Reaction Name: Recovery of RNA synthesis after TC-NER See in Reactome R-HSA-9011975 ( R-HSA-9018519 ) R-HSA-9011975 Reaction Name: Estrogen-responsive MYC gene expression See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-2976551 ( R-HSA-2197563 ) R-HSA-2976551 Reaction Name: NOTCH2 stimulates GZMB transcription See in Reactome R-HSA-1368081 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-1368081 Reaction Name: Expression of SREBF1 (SREBP1) See in Reactome R-HSA-5617431 ( R-HSA-5617472 ) R-HSA-5617431 Reaction Name: Retinoic acid activates HOXA1 chromatin See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-3215152 ( R-HSA-6804114 ) R-HSA-3215152 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter See in Reactome R-HSA-4088152 ( R-HSA-156711 ) R-HSA-4088152 Reaction Name: FOXM1 stimulates CDC25A transcription See in Reactome R-HSA-9009371 ( R-HSA-9018519 ) R-HSA-9009371 Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter See in Reactome R-HSA-9023859 ( R-HSA-9018519 ) R-HSA-9023859 Reaction Name: Estrogen-responsive TFF1 gene expression See in Reactome R-HSA-1368087 ( R-HSA-400253 ) R-HSA-1368087 Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-3899291 ( R-HSA-3899300 ) R-HSA-3899291 Reaction Name: SUMOylation of EP300 with SUMO1 See in Reactome R-HSA-9634433 ( R-HSA-9616222 ) R-HSA-9634433 Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid See in Reactome R-HSA-9605057 ( R-HSA-9029569 ) R-HSA-9605057 Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 See in Reactome R-HSA-5617471 ( R-HSA-5617472 ) R-HSA-5617471 Reaction Name: HOXA1 gene is transcribed See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-5691381 ( R-HSA-5689901 ) R-HSA-5691381 Reaction Name: MYSM1 deubiquitinates Histone H2A See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9018499 ( R-HSA-9018519 ) R-HSA-9018499 Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-6782131 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782131 Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-8935740 ( R-HSA-8936459 ) R-HSA-8935740 Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene See in Reactome R-HSA-9009378 ( R-HSA-9018519 ) R-HSA-9009378 Reaction Name: Estrogen-responsive CCND1 gene expression See in Reactome R-HSA-8952419 ( R-HSA-8941858 ) R-HSA-8952419 Reaction Name: SMURFs ubiquitinate RUNX3 See in Reactome R-HSA-6782224 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782224 Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER See in Reactome R-HSA-8936979 ( R-HSA-8936459 ) R-HSA-8936979 Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-3215144 ( R-HSA-6804114 ) R-HSA-3215144 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription See in Reactome R-HSA-8951966 ( R-HSA-8951936 ) R-HSA-8951966 Reaction Name: EP300 acetylates RUNX3 See in Reactome R-HSA-9008271 ( R-HSA-9018519 ) R-HSA-9008271 Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter See in Reactome R-HSA-9011941 ( R-HSA-9018519 ) R-HSA-9011941 Reaction Name: Estrogen-responsive BCL2 gene expression See in Reactome R-HSA-2976563 ( R-HSA-2197563 ) R-HSA-2976563 Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter See in Reactome R-HSA-5663273 ( R-HSA-400253 ) R-HSA-5663273 Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-6782141 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782141 Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-8937037 ( R-HSA-8936459 ) R-HSA-8937037 Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-9617735 ( R-HSA-9617629 ) R-HSA-9617735 Reaction Name: TXN disrupts FOXO4 complex with EP300 See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-9018497 ( R-HSA-9018519 ) R-HSA-9018497 Reaction Name: Estrogen-responsive TFF3 gene expression See in Reactome R-HSA-8936995 ( R-HSA-8936459 ) R-HSA-8936995 Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9684118 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-9684118 Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-6804242 ( R-HSA-6804760 ) R-HSA-6804242 Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5 See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-3222093 ( R-HSA-6804758 ) R-HSA-3222093 Reaction Name: BRD7 binds TP53 and EP300 See in Reactome
MONDO:0019438	CDK4	P11802	2.7.11.22	R-HSA-2559585 R-HSA-2559585 Reactome Name: Oncogene Induced Senescence See in Reactome R-HSA-2559580 R-HSA-2559580 Reactome Name: Oxidative Stress Induced Senescence See in Reactome R-HSA-2559582 R-HSA-2559582 Reactome Name: Senescence-Associated Secretory Phenotype (SASP) See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-912446 R-HSA-912446 Reactome Name: Meiotic recombination See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-8849470 R-HSA-8849470 Reactome Name: PTK6 Regulates Cell Cycle See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-75815 R-HSA-75815 Reactome Name: Ubiquitin-dependent degradation of Cyclin D See in Reactome R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-187577 R-HSA-187577 Reactome Name: SCF(Skp2)-mediated degradation of p27/p21 See in Reactome	R-HSA-8848021 R-HSA-8848021 Reactome Name: Signaling by PTK6 See in Reactome R-HSA-2559583 R-HSA-2559583 Reactome Name: Cellular Senescence See in Reactome R-HSA-9006927 R-HSA-9006927 Reactome Name: Signaling by Non-Receptor Tyrosine Kinases See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1474165 R-HSA-1474165 Reactome Name: Reproduction See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-69656 R-HSA-69656 Reactome Name: Cyclin A:Cdk2-associated events at S phase entry See in Reactome R-HSA-69206 R-HSA-69206 Reactome Name: G1/S Transition See in Reactome R-HSA-69202 R-HSA-69202 Reactome Name: Cyclin E associated events during G1/S transition See in Reactome R-HSA-69242 R-HSA-69242 Reactome Name: S Phase See in Reactome R-HSA-1500620 R-HSA-1500620 Reactome Name: Meiosis See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction	R-HSA-1226094 ( R-HSA-69231 ) R-HSA-1226094 Reaction Name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex See in Reactome R-HSA-1226095 ( R-HSA-69231 ) R-HSA-1226095 Reaction Name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex See in Reactome R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-182594 Reaction Name: Association of INK4 family proteins with CDK4/6 See in Reactome R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215385 Reaction Name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 See in Reactome R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-3215426 Reaction Name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 See in Reactome R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205799 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) See in Reactome R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5205861 Reaction Name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) See in Reactome R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-5216234 Reaction Name: PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-5661117 Reaction Name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 See in Reactome R-HSA-69227 ( R-HSA-69231 ) R-HSA-69227 Reaction Name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-75820 ( R-HSA-75815 ) R-HSA-75820 Reaction Name: Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta See in Reactome R-HSA-75822 ( R-HSA-75815 ) R-HSA-75822 Reaction Name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm See in Reactome R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848414 Reaction Name: Activated PTK6 binds CDKN1B See in Reactome R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 Reaction Name: PTK6 phosphorylates CDKN1B See in Reactome R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941895 Reaction Name: Formation of CDK4/6:CCND complexes See in Reactome R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8941915 Reaction Name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes See in Reactome R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942607 Reaction Name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes See in Reactome R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942803 Reaction Name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus See in Reactome R-HSA-8942836 ( R-HSA-69231 ) R-HSA-8942836 Reaction Name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 See in Reactome R-HSA-9008412 ( R-HSA-212436; R-HSA-8878166 ) R-HSA-9008412 Reaction Name: CDK4 phosphorylates RUNX2 See in Reactome R-HSA-9018017 ( R-HSA-69231 ) R-HSA-9018017 Reaction Name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes See in Reactome R-HSA-912429 ( R-HSA-912446 ) R-HSA-912429 Reaction Name: Resolution of meiotic holliday junction See in Reactome R-HSA-912458 ( R-HSA-912446 ) R-HSA-912458 Reaction Name: Formation of meiotic heteroduplex See in Reactome R-HSA-912496 ( R-HSA-912446 ) R-HSA-912496 Reaction Name: Formation of meiotic holliday junction See in Reactome R-HSA-912503 ( R-HSA-912446 ) R-HSA-912503 Reaction Name: Formation of meiotic single-stranded DNA invasion complex See in Reactome R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9624112 Reaction Name: CEBPA binds CDK4 See in Reactome R-HSA-9754130 ( R-HSA-69231 ) R-HSA-9754130 Reaction Name: CDK4 inhibitors bind CDK4 See in Reactome
MONDO:0020763	CREBBP	Q92793	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-8939246 R-HSA-8939246 Reactome Name: RUNX1 regulates transcription of genes involved in differentiation of myeloid cells See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2151201 R-HSA-2151201 Reactome Name: Transcriptional activation of mitochondrial biogenesis See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-350054 R-HSA-350054 Reactome Name: Notch-HLH transcription pathway See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-6803204 R-HSA-6803204 Reactome Name: TP53 Regulates Transcription of Genes Involved in Cytochrome C Release See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-1368108 R-HSA-1368108 Reactome Name: BMAL1:CLOCK,NPAS2 activates circadian gene expression See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9707564 R-HSA-9707564 Reactome Name: Cytoprotection by HMOX1 See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-1592230 R-HSA-1592230 Reactome Name: Mitochondrial biogenesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5633008 R-HSA-5633008 Reactome Name: TP53 Regulates Transcription of Cell Death Genes See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-1852241 R-HSA-1852241 Reactome Name: Organelle biogenesis and maintenance See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-9711123 R-HSA-9711123 Reactome Name: Cellular response to chemical stress See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome	Circadian Clock Immune System Metabolism Developmental Biology Gene expression (Transcription) Organelle biogenesis and maintenance Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-1989746 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989746 Reaction Name: Expression of CYP7A1 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-1989756 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989756 Reaction Name: Expression of ME1 See in Reactome R-HSA-1989754 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989754 Reaction Name: Expression of APOA1 See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-1989755 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989755 Reaction Name: Expression of CYP4A11 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-1989753 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989753 Reaction Name: Expression of PEX11A See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-8938231 ( R-HSA-8939246 ) R-HSA-8938231 Reaction Name: RUNX1:CBFB binds CREBBP See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-400143 ( R-HSA-400206; R-HSA-9707564 ) R-HSA-400143 Reaction Name: Fatty acid ligands activate PPARA See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-1592238 ( R-HSA-1989781; R-HSA-2151201; R-HSA-400206 ) R-HSA-1592238 Reaction Name: Expression of ALAS1 See in Reactome R-HSA-1989751 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989751 Reaction Name: Expression of FABP1 See in Reactome R-HSA-1989777 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989777 Reaction Name: Expression of RGL1 See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-1989745 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989745 Reaction Name: Expression of ACADM See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-1989772 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989772 Reaction Name: Expression of GLIPR1 See in Reactome R-HSA-1989771 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989771 Reaction Name: Expression of TNFRSF21 See in Reactome R-HSA-1655850 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655850 Reaction Name: Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) See in Reactome R-HSA-3927959 ( R-HSA-3899300 ) R-HSA-3927959 Reaction Name: SUMOylation of CREBBP with SUMO1 See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400206; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-212356 ( R-HSA-350054 ) R-HSA-212356 Reaction Name: Formation of CSL-NICD coactivator complex See in Reactome R-HSA-879724 ( R-HSA-1368108; R-HSA-1989781; R-HSA-400206; R-HSA-400253 ) R-HSA-879724 Reaction Name: Expression of PPARA See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-9626945 ( R-HSA-9617629 ) R-HSA-9626945 Reaction Name: CREBBP acetylates FOXO1 See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-6798004 ( R-HSA-6803204 ) R-HSA-6798004 Reaction Name: TP53 stimulates BNIP3L expression See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-1989773 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989773 Reaction Name: Expression of CPT2 See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-8938228 ( R-HSA-8939246 ) R-HSA-8938228 Reaction Name: RUNX1:CBFB:CREBBP binds the CSF2 (GM-CSF) gene promoter See in Reactome R-HSA-1989765 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989765 Reaction Name: Expression of ABCA1 See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-1989764 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989764 Reaction Name: Expression of CYP1A1 See in Reactome R-HSA-1989758 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989758 Reaction Name: Expression of UGT1A9 See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1989750 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989750 Reaction Name: Expression of FATP1 (SLC27A1) See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-1989775 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989775 Reaction Name: Expression of SULT2A1 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-1989747 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989747 Reaction Name: Expression of FHL2 See in Reactome R-HSA-1989776 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989776 Reaction Name: Expression of APOA2 See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-3697008 ( R-HSA-3214847 ) R-HSA-3697008 Reaction Name: CREBBP acetylates histone H2B, H3, H4 See in Reactome R-HSA-1989760 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989760 Reaction Name: Expression of HMGCS2 See in Reactome R-HSA-1989770 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989770 Reaction Name: Expression of PLIN2 See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-1989762 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989762 Reaction Name: Expression of ABCB4 See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-9626928 ( R-HSA-9617629 ) R-HSA-9626928 Reaction Name: CREBBP binds FOXO1 See in Reactome R-HSA-1989757 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989757 Reaction Name: Expression of FADS1 See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400206; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-1989778 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989778 Reaction Name: Expression of ACSL1 See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-1989767 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989767 Reaction Name: Expression of TRIB3 See in Reactome R-HSA-8938251 ( R-HSA-8939246 ) R-HSA-8938251 Reaction Name: CSF2 (GM-CSF) gene expression is stimulated by RUNX1 and CREBBP See in Reactome R-HSA-1989748 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989748 Reaction Name: Expression of GRHL1 See in Reactome R-HSA-4395227 ( R-HSA-1912408 ) R-HSA-4395227 Reaction Name: CCND1:CREBBP binds NOTCH1 promoter See in Reactome R-HSA-1989779 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989779 Reaction Name: Expression of ANKRD1 See in Reactome R-HSA-1989759 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989759 Reaction Name: Expression of G0S2 See in Reactome R-HSA-1655848 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655848 Reaction Name: Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-1989752 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989752 Reaction Name: Expression of TXNRD1 See in Reactome R-HSA-1989749 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989749 Reaction Name: Expression of ACOX1 See in Reactome R-HSA-1989761 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989761 Reaction Name: Expression of APOA5 See in Reactome R-HSA-1989768 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989768 Reaction Name: Expression of TIAM2 See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-1655826 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655826 Reaction Name: Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) See in Reactome R-HSA-1989774 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989774 Reaction Name: Expression of AGT See in Reactome R-HSA-6797993 ( R-HSA-6803204 ) R-HSA-6797993 Reaction Name: TP53 and CREBBP bind BNIP3L gene See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome
MONDO:0020769	EP300	Q09472	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-5689901 R-HSA-5689901 Reactome Name: Metalloprotease DUBs See in Reactome R-HSA-6804760 R-HSA-6804760 Reactome Name: Regulation of TP53 Activity through Methylation See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-6782135 R-HSA-6782135 Reactome Name: Dual incision in TC-NER See in Reactome R-HSA-6782210 R-HSA-6782210 Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-6804114 R-HSA-6804114 Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-6781827 R-HSA-6781827 Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER) See in Reactome R-HSA-156711 R-HSA-156711 Reactome Name: Polo-like kinase mediated events See in Reactome R-HSA-5250924 R-HSA-5250924 Reactome Name: B-WICH complex positively regulates rRNA expression See in Reactome R-HSA-6781823 R-HSA-6781823 Reactome Name: Formation of TC-NER Pre-Incision Complex See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-9701898 R-HSA-9701898 Reactome Name: STAT3 nuclear events downstream of ALK signaling See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8936459 R-HSA-8936459 Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2197563 R-HSA-2197563 Reactome Name: NOTCH2 intracellular domain regulates transcription See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8951936 R-HSA-8951936 Reactome Name: RUNX3 regulates p14-ARF See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-6811555 R-HSA-6811555 Reactome Name: PI5P Regulates TP53 Acetylation See in Reactome R-HSA-6804758 R-HSA-6804758 Reactome Name: Regulation of TP53 Activity through Acetylation See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-6791312 R-HSA-6791312 Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-5696398 R-HSA-5696398 Reactome Name: Nucleotide Excision Repair See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-1980145 R-HSA-1980145 Reactome Name: Signaling by NOTCH2 See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-5250913 R-HSA-5250913 Reactome Name: Positive epigenetic regulation of rRNA expression See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome	Circadian Clock Immune System Cell Cycle Developmental Biology Metabolism Gene expression (Transcription) DNA Repair Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-6782069 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782069 Reaction Name: UVSSA:USP7 deubiquitinates ERCC6 See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome R-HSA-9011981 ( R-HSA-9018519 ) R-HSA-9011981 Reaction Name: EP300 is recruited to MYC and BCL2 genes See in Reactome R-HSA-8878050 ( R-HSA-8939243 ) R-HSA-8878050 Reaction Name: HIPK2 phosphorylates RUNX1 and EP300 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-8952101 ( R-HSA-8951936 ) R-HSA-8952101 Reaction Name: p14-ARF transcription is stimulated by RUNX proteins See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9038163 ( R-HSA-9018519 ) R-HSA-9038163 Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-6782211 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782211 Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-9613451 ( R-HSA-9031628 ) R-HSA-9613451 Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes See in Reactome R-HSA-8936621 ( R-HSA-8936459 ) R-HSA-8936621 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter See in Reactome R-HSA-5628871 ( R-HSA-6804758 ) R-HSA-5628871 Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9620723 ( R-HSA-9031628 ) R-HSA-9620723 Reaction Name: VGF gene expression See in Reactome R-HSA-5250938 ( R-HSA-5250924 ) R-HSA-5250938 Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 See in Reactome R-HSA-6782204 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782204 Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER See in Reactome R-HSA-5617867 ( R-HSA-5617472 ) R-HSA-5617867 Reaction Name: HOXB4 gene is transcribed See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-9023884 ( R-HSA-9018519 ) R-HSA-9023884 Reaction Name: NCOA1 recruits EP300 to TGFA promoter See in Reactome R-HSA-8937050 ( R-HSA-8936459 ) R-HSA-8937050 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter See in Reactome R-HSA-8952081 ( R-HSA-8951936 ) R-HSA-8952081 Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus See in Reactome R-HSA-3662335 ( R-HSA-3214847 ) R-HSA-3662335 Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4 See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-6804379 ( R-HSA-6804760 ) R-HSA-6804379 Reaction Name: PRMT5 binds TTC5 See in Reactome R-HSA-4088162 ( R-HSA-156711 ) R-HSA-4088162 Reaction Name: FOXM1 binds CDC25A promoter See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-9023846 ( R-HSA-9018519 ) R-HSA-9023846 Reaction Name: Estrogen-responsive CTSD expression See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-9008315 ( R-HSA-9018519 ) R-HSA-9008315 Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen See in Reactome R-HSA-8936628 ( R-HSA-8936459 ) R-HSA-8936628 Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9023860 ( R-HSA-9018519 ) R-HSA-9023860 Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-8936481 ( R-HSA-8936459 ) R-HSA-8936481 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter See in Reactome R-HSA-5663264 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663264 Reaction Name: RORA, EP300 bind CPT1A gene See in Reactome R-HSA-6805650 ( R-HSA-6804758 ) R-HSA-6805650 Reaction Name: MTA2-NuRD complex deacetylates TP53 See in Reactome R-HSA-5617452 ( R-HSA-5617472 ) R-HSA-5617452 Reaction Name: Retinoic acid activates HOXB1 chromatin See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-9613460 ( R-HSA-9031628 ) R-HSA-9613460 Reaction Name: ID1 and ID3 gene expression See in Reactome R-HSA-9620717 ( R-HSA-9031628 ) R-HSA-9620717 Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter See in Reactome R-HSA-8951951 ( R-HSA-8951936 ) R-HSA-8951951 Reaction Name: RUNX3 binds EP300 See in Reactome R-HSA-9029561 ( R-HSA-9029569 ) R-HSA-9029561 Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-9617064 ( R-HSA-9616222 ) R-HSA-9617064 Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene See in Reactome R-HSA-9008285 ( R-HSA-9018519 ) R-HSA-9008285 Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-9701531 ( R-HSA-9701898 ) R-HSA-9701531 Reaction Name: p-Y705,S727 STAT3 is acetylated See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-8937097 ( R-HSA-8936459 ) R-HSA-8937097 Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-8936616 ( R-HSA-8936459 ) R-HSA-8936616 Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene See in Reactome R-HSA-5663246 ( R-HSA-400253 ) R-HSA-5663246 Reaction Name: RORA, EP300 bind NPAS2 gene See in Reactome R-HSA-6804229 ( R-HSA-6804760 ) R-HSA-6804229 Reaction Name: JMY, TTC5 and EP300 bind See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-8878056 ( R-HSA-8939243 ) R-HSA-8878056 Reaction Name: RUNX1:CBFB binds EP300 See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-6782004 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782004 Reaction Name: Assembly of the pre-incision complex in TC-NER See in Reactome R-HSA-5250930 ( R-HSA-5250924 ) R-HSA-5250930 Reaction Name: B-WICH recruits histone acetyltransferases See in Reactome R-HSA-8937016 ( R-HSA-8936459 ) R-HSA-8937016 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter See in Reactome R-HSA-400342 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-400342 Reaction Name: Expression of ARNTL (BMAL1) See in Reactome R-HSA-6782138 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782138 Reaction Name: ERCC5 and RPA bind TC-NER site See in Reactome R-HSA-5617859 ( R-HSA-5617472 ) R-HSA-5617859 Reaction Name: Retinoic acid activates HOXB4 chromatin See in Reactome R-HSA-8952058 ( R-HSA-8951936 ) R-HSA-8952058 Reaction Name: CCND1 binds RUNX3 and displaces EP300 See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-9620515 ( R-HSA-9617629 ) R-HSA-9620515 Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-5693644 ( R-HSA-5617472 ) R-HSA-5693644 Reaction Name: HOXB1 maintains activation of HOXB1 chromatin See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-5617862 ( R-HSA-5617472 ) R-HSA-5617862 Reaction Name: Retinoic acid activates HOXA4 chromatin See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-8935731 ( R-HSA-8936459 ) R-HSA-8935731 Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-6782208 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782208 Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER See in Reactome R-HSA-5663293 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663293 Reaction Name: RORA, EP300 bind SREBF1 gene See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-549475 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-549475 Reaction Name: Expression of NR1D1 (REV-ERBA) See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-6782227 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782227 Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER See in Reactome R-HSA-6811508 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811508 Reaction Name: ING2-bound EP300 acetylates TP53 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-8951977 ( R-HSA-8951936 ) R-HSA-8951977 Reaction Name: Acetylated RUNX3 binds to BRD2 See in Reactome R-HSA-9023840 ( R-HSA-9018519 ) R-HSA-9023840 Reaction Name: HATs and coactivators are recruited to the CTSD gene See in Reactome R-HSA-6811479 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811479 Reaction Name: ING2 recruits EP300 to TP53 See in Reactome R-HSA-5617877 ( R-HSA-5617472 ) R-HSA-5617877 Reaction Name: HOXA4 gene is transcribed See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-6804383 ( R-HSA-6804760 ) R-HSA-6804383 Reaction Name: PRMT5 methylates TP53 See in Reactome R-HSA-6782234 ( R-HSA-6781827 ) R-HSA-6782234 Reaction Name: Recovery of RNA synthesis after TC-NER See in Reactome R-HSA-9011975 ( R-HSA-9018519 ) R-HSA-9011975 Reaction Name: Estrogen-responsive MYC gene expression See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-2976551 ( R-HSA-2197563 ) R-HSA-2976551 Reaction Name: NOTCH2 stimulates GZMB transcription See in Reactome R-HSA-1368081 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-1368081 Reaction Name: Expression of SREBF1 (SREBP1) See in Reactome R-HSA-5617431 ( R-HSA-5617472 ) R-HSA-5617431 Reaction Name: Retinoic acid activates HOXA1 chromatin See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-3215152 ( R-HSA-6804114 ) R-HSA-3215152 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter See in Reactome R-HSA-4088152 ( R-HSA-156711 ) R-HSA-4088152 Reaction Name: FOXM1 stimulates CDC25A transcription See in Reactome R-HSA-9009371 ( R-HSA-9018519 ) R-HSA-9009371 Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter See in Reactome R-HSA-9023859 ( R-HSA-9018519 ) R-HSA-9023859 Reaction Name: Estrogen-responsive TFF1 gene expression See in Reactome R-HSA-1368087 ( R-HSA-400253 ) R-HSA-1368087 Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-3899291 ( R-HSA-3899300 ) R-HSA-3899291 Reaction Name: SUMOylation of EP300 with SUMO1 See in Reactome R-HSA-9634433 ( R-HSA-9616222 ) R-HSA-9634433 Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid See in Reactome R-HSA-9605057 ( R-HSA-9029569 ) R-HSA-9605057 Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 See in Reactome R-HSA-5617471 ( R-HSA-5617472 ) R-HSA-5617471 Reaction Name: HOXA1 gene is transcribed See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-5691381 ( R-HSA-5689901 ) R-HSA-5691381 Reaction Name: MYSM1 deubiquitinates Histone H2A See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9018499 ( R-HSA-9018519 ) R-HSA-9018499 Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-6782131 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782131 Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-8935740 ( R-HSA-8936459 ) R-HSA-8935740 Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene See in Reactome R-HSA-9009378 ( R-HSA-9018519 ) R-HSA-9009378 Reaction Name: Estrogen-responsive CCND1 gene expression See in Reactome R-HSA-8952419 ( R-HSA-8941858 ) R-HSA-8952419 Reaction Name: SMURFs ubiquitinate RUNX3 See in Reactome R-HSA-6782224 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782224 Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER See in Reactome R-HSA-8936979 ( R-HSA-8936459 ) R-HSA-8936979 Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-3215144 ( R-HSA-6804114 ) R-HSA-3215144 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription See in Reactome R-HSA-8951966 ( R-HSA-8951936 ) R-HSA-8951966 Reaction Name: EP300 acetylates RUNX3 See in Reactome R-HSA-9008271 ( R-HSA-9018519 ) R-HSA-9008271 Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter See in Reactome R-HSA-9011941 ( R-HSA-9018519 ) R-HSA-9011941 Reaction Name: Estrogen-responsive BCL2 gene expression See in Reactome R-HSA-2976563 ( R-HSA-2197563 ) R-HSA-2976563 Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter See in Reactome R-HSA-5663273 ( R-HSA-400253 ) R-HSA-5663273 Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-6782141 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782141 Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-8937037 ( R-HSA-8936459 ) R-HSA-8937037 Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-9617735 ( R-HSA-9617629 ) R-HSA-9617735 Reaction Name: TXN disrupts FOXO4 complex with EP300 See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-9018497 ( R-HSA-9018519 ) R-HSA-9018497 Reaction Name: Estrogen-responsive TFF3 gene expression See in Reactome R-HSA-8936995 ( R-HSA-8936459 ) R-HSA-8936995 Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9684118 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-9684118 Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-6804242 ( R-HSA-6804760 ) R-HSA-6804242 Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5 See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-3222093 ( R-HSA-6804758 ) R-HSA-3222093 Reaction Name: BRD7 binds TP53 and EP300 See in Reactome
MONDO:0021230	EP300	Q09472	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-5689901 R-HSA-5689901 Reactome Name: Metalloprotease DUBs See in Reactome R-HSA-6804760 R-HSA-6804760 Reactome Name: Regulation of TP53 Activity through Methylation See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-9616222 R-HSA-9616222 Reactome Name: Transcriptional regulation of granulopoiesis See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-6782135 R-HSA-6782135 Reactome Name: Dual incision in TC-NER See in Reactome R-HSA-6782210 R-HSA-6782210 Reactome Name: Gap-filling DNA repair synthesis and ligation in TC-NER See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-8941858 R-HSA-8941858 Reactome Name: Regulation of RUNX3 expression and activity See in Reactome R-HSA-6804114 R-HSA-6804114 Reactome Name: TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-6781827 R-HSA-6781827 Reactome Name: Transcription-Coupled Nucleotide Excision Repair (TC-NER) See in Reactome R-HSA-156711 R-HSA-156711 Reactome Name: Polo-like kinase mediated events See in Reactome R-HSA-5250924 R-HSA-5250924 Reactome Name: B-WICH complex positively regulates rRNA expression See in Reactome R-HSA-6781823 R-HSA-6781823 Reactome Name: Formation of TC-NER Pre-Incision Complex See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-9701898 R-HSA-9701898 Reactome Name: STAT3 nuclear events downstream of ALK signaling See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8936459 R-HSA-8936459 Reactome Name: RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2197563 R-HSA-2197563 Reactome Name: NOTCH2 intracellular domain regulates transcription See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-8951936 R-HSA-8951936 Reactome Name: RUNX3 regulates p14-ARF See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-6811555 R-HSA-6811555 Reactome Name: PI5P Regulates TP53 Acetylation See in Reactome R-HSA-6804758 R-HSA-6804758 Reactome Name: Regulation of TP53 Activity through Acetylation See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-6791312 R-HSA-6791312 Reactome Name: TP53 Regulates Transcription of Cell Cycle Genes See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-5696398 R-HSA-5696398 Reactome Name: Nucleotide Excision Repair See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-453274 R-HSA-453274 Reactome Name: Mitotic G2-G2/M phases See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-1980145 R-HSA-1980145 Reactome Name: Signaling by NOTCH2 See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-5688426 R-HSA-5688426 Reactome Name: Deubiquitination See in Reactome R-HSA-201556 R-HSA-201556 Reactome Name: Signaling by ALK See in Reactome R-HSA-5250913 R-HSA-5250913 Reactome Name: Positive epigenetic regulation of rRNA expression See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-69275 R-HSA-69275 Reactome Name: G2/M Transition See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome	Circadian Clock Immune System Cell Cycle Developmental Biology Metabolism Gene expression (Transcription) DNA Repair Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-6782069 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782069 Reaction Name: UVSSA:USP7 deubiquitinates ERCC6 See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome R-HSA-9011981 ( R-HSA-9018519 ) R-HSA-9011981 Reaction Name: EP300 is recruited to MYC and BCL2 genes See in Reactome R-HSA-8878050 ( R-HSA-8939243 ) R-HSA-8878050 Reaction Name: HIPK2 phosphorylates RUNX1 and EP300 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-8952101 ( R-HSA-8951936 ) R-HSA-8952101 Reaction Name: p14-ARF transcription is stimulated by RUNX proteins See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9038163 ( R-HSA-9018519 ) R-HSA-9038163 Reaction Name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-6782211 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782211 Reaction Name: DNA polymerases delta, epsilon or kappa bind the TC-NER site See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-9613451 ( R-HSA-9031628 ) R-HSA-9613451 Reaction Name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes See in Reactome R-HSA-8936621 ( R-HSA-8936459 ) R-HSA-8936621 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter See in Reactome R-HSA-5628871 ( R-HSA-6804758 ) R-HSA-5628871 Reaction Name: BRD7 promotes EP300-mediated acetylation of TP53 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9620723 ( R-HSA-9031628 ) R-HSA-9620723 Reaction Name: VGF gene expression See in Reactome R-HSA-5250938 ( R-HSA-5250924 ) R-HSA-5250938 Reaction Name: B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 See in Reactome R-HSA-6782204 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782204 Reaction Name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER See in Reactome R-HSA-5617867 ( R-HSA-5617472 ) R-HSA-5617867 Reaction Name: HOXB4 gene is transcribed See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-9023884 ( R-HSA-9018519 ) R-HSA-9023884 Reaction Name: NCOA1 recruits EP300 to TGFA promoter See in Reactome R-HSA-8937050 ( R-HSA-8936459 ) R-HSA-8937050 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter See in Reactome R-HSA-8952081 ( R-HSA-8951936 ) R-HSA-8952081 Reaction Name: RUNX proteins bind the p14-ARF promoter at the CDKN2A locus See in Reactome R-HSA-3662335 ( R-HSA-3214847 ) R-HSA-3662335 Reaction Name: EP300 acetylates histone H2A, H2B, H3, H4 See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-6804379 ( R-HSA-6804760 ) R-HSA-6804379 Reaction Name: PRMT5 binds TTC5 See in Reactome R-HSA-4088162 ( R-HSA-156711 ) R-HSA-4088162 Reaction Name: FOXM1 binds CDC25A promoter See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-9023846 ( R-HSA-9018519 ) R-HSA-9023846 Reaction Name: Estrogen-responsive CTSD expression See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-9008315 ( R-HSA-9018519 ) R-HSA-9008315 Reaction Name: TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen See in Reactome R-HSA-8936628 ( R-HSA-8936459 ) R-HSA-8936628 Reaction Name: GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9023860 ( R-HSA-9018519 ) R-HSA-9023860 Reaction Name: Histone acetyltransferases are recruited to the TFF1 gene See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-8936481 ( R-HSA-8936459 ) R-HSA-8936481 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter See in Reactome R-HSA-5663264 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663264 Reaction Name: RORA, EP300 bind CPT1A gene See in Reactome R-HSA-6805650 ( R-HSA-6804758 ) R-HSA-6805650 Reaction Name: MTA2-NuRD complex deacetylates TP53 See in Reactome R-HSA-5617452 ( R-HSA-5617472 ) R-HSA-5617452 Reaction Name: Retinoic acid activates HOXB1 chromatin See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-9613460 ( R-HSA-9031628 ) R-HSA-9613460 Reaction Name: ID1 and ID3 gene expression See in Reactome R-HSA-9620717 ( R-HSA-9031628 ) R-HSA-9620717 Reaction Name: p-CREB, ASCL1, TCF12, ATFs and p300 bind the VGF promoter See in Reactome R-HSA-8951951 ( R-HSA-8951936 ) R-HSA-8951951 Reaction Name: RUNX3 binds EP300 See in Reactome R-HSA-9029561 ( R-HSA-9029569 ) R-HSA-9029561 Reaction Name: NCOA1 recruits EP300 to the ABCA1 promoter See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-9617064 ( R-HSA-9616222 ) R-HSA-9617064 Reaction Name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene See in Reactome R-HSA-9008285 ( R-HSA-9018519 ) R-HSA-9008285 Reaction Name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-9701531 ( R-HSA-9701898 ) R-HSA-9701531 Reaction Name: p-Y705,S727 STAT3 is acetylated See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-8937097 ( R-HSA-8936459 ) R-HSA-8937097 Reaction Name: MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-8936616 ( R-HSA-8936459 ) R-HSA-8936616 Reaction Name: RUNX1 and GATA1 bind the promoter of the GP1BA gene See in Reactome R-HSA-5663246 ( R-HSA-400253 ) R-HSA-5663246 Reaction Name: RORA, EP300 bind NPAS2 gene See in Reactome R-HSA-6804229 ( R-HSA-6804760 ) R-HSA-6804229 Reaction Name: JMY, TTC5 and EP300 bind See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-8878056 ( R-HSA-8939243 ) R-HSA-8878056 Reaction Name: RUNX1:CBFB binds EP300 See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-5617454 ( R-HSA-5617472 ) R-HSA-5617454 Reaction Name: HOXB1 gene is transcribed See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-6782004 ( R-HSA-6781823; R-HSA-6781827 ) R-HSA-6782004 Reaction Name: Assembly of the pre-incision complex in TC-NER See in Reactome R-HSA-5250930 ( R-HSA-5250924 ) R-HSA-5250930 Reaction Name: B-WICH recruits histone acetyltransferases See in Reactome R-HSA-8937016 ( R-HSA-8936459 ) R-HSA-8937016 Reaction Name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter See in Reactome R-HSA-400342 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-400342 Reaction Name: Expression of ARNTL (BMAL1) See in Reactome R-HSA-6782138 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782138 Reaction Name: ERCC5 and RPA bind TC-NER site See in Reactome R-HSA-5617859 ( R-HSA-5617472 ) R-HSA-5617859 Reaction Name: Retinoic acid activates HOXB4 chromatin See in Reactome R-HSA-8952058 ( R-HSA-8951936 ) R-HSA-8952058 Reaction Name: CCND1 binds RUNX3 and displaces EP300 See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-9620515 ( R-HSA-9617629 ) R-HSA-9620515 Reaction Name: KAT2B,EP300 acetylate FOXO3 under oxidative stress See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-5693644 ( R-HSA-5617472 ) R-HSA-5693644 Reaction Name: HOXB1 maintains activation of HOXB1 chromatin See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-5617862 ( R-HSA-5617472 ) R-HSA-5617862 Reaction Name: Retinoic acid activates HOXA4 chromatin See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-8935731 ( R-HSA-8936459 ) R-HSA-8935731 Reaction Name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-6782208 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782208 Reaction Name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER See in Reactome R-HSA-5663293 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-5663293 Reaction Name: RORA, EP300 bind SREBF1 gene See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-549475 ( R-HSA-400253; R-HSA-9707616 ) R-HSA-549475 Reaction Name: Expression of NR1D1 (REV-ERBA) See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-6782227 ( R-HSA-6781827; R-HSA-6782210 ) R-HSA-6782227 Reaction Name: Ligation of newly synthesized repair patch to incised DNA in TC-NER See in Reactome R-HSA-6811508 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811508 Reaction Name: ING2-bound EP300 acetylates TP53 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-8951977 ( R-HSA-8951936 ) R-HSA-8951977 Reaction Name: Acetylated RUNX3 binds to BRD2 See in Reactome R-HSA-9023840 ( R-HSA-9018519 ) R-HSA-9023840 Reaction Name: HATs and coactivators are recruited to the CTSD gene See in Reactome R-HSA-6811479 ( R-HSA-6804758; R-HSA-6811555 ) R-HSA-6811479 Reaction Name: ING2 recruits EP300 to TP53 See in Reactome R-HSA-5617877 ( R-HSA-5617472 ) R-HSA-5617877 Reaction Name: HOXA4 gene is transcribed See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-6804383 ( R-HSA-6804760 ) R-HSA-6804383 Reaction Name: PRMT5 methylates TP53 See in Reactome R-HSA-6782234 ( R-HSA-6781827 ) R-HSA-6782234 Reaction Name: Recovery of RNA synthesis after TC-NER See in Reactome R-HSA-9011975 ( R-HSA-9018519 ) R-HSA-9011975 Reaction Name: Estrogen-responsive MYC gene expression See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-2976551 ( R-HSA-2197563 ) R-HSA-2976551 Reaction Name: NOTCH2 stimulates GZMB transcription See in Reactome R-HSA-1368081 ( R-HSA-1368082; R-HSA-400253 ) R-HSA-1368081 Reaction Name: Expression of SREBF1 (SREBP1) See in Reactome R-HSA-5617431 ( R-HSA-5617472 ) R-HSA-5617431 Reaction Name: Retinoic acid activates HOXA1 chromatin See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-3215152 ( R-HSA-6804114 ) R-HSA-3215152 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter See in Reactome R-HSA-4088152 ( R-HSA-156711 ) R-HSA-4088152 Reaction Name: FOXM1 stimulates CDC25A transcription See in Reactome R-HSA-9009371 ( R-HSA-9018519 ) R-HSA-9009371 Reaction Name: Binding of AP1 transcriptional activator complexes to CCND1 promoter See in Reactome R-HSA-9023859 ( R-HSA-9018519 ) R-HSA-9023859 Reaction Name: Estrogen-responsive TFF1 gene expression See in Reactome R-HSA-1368087 ( R-HSA-400253 ) R-HSA-1368087 Reaction Name: RORA, EP300, PPARGC1A, NRIP1 bind ARNTL (BMAL1) gene See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-3899291 ( R-HSA-3899300 ) R-HSA-3899291 Reaction Name: SUMOylation of EP300 with SUMO1 See in Reactome R-HSA-9634433 ( R-HSA-9616222 ) R-HSA-9634433 Reaction Name: CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid See in Reactome R-HSA-9605057 ( R-HSA-9029569 ) R-HSA-9605057 Reaction Name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 See in Reactome R-HSA-5617471 ( R-HSA-5617472 ) R-HSA-5617471 Reaction Name: HOXA1 gene is transcribed See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-5691381 ( R-HSA-5689901 ) R-HSA-5691381 Reaction Name: MYSM1 deubiquitinates Histone H2A See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9018499 ( R-HSA-9018519 ) R-HSA-9018499 Reaction Name: ESR1:ESTG and EP300 are recruited to TFF3 promoter See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-6782131 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782131 Reaction Name: ERCC2-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-8935740 ( R-HSA-8936459 ) R-HSA-8935740 Reaction Name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene See in Reactome R-HSA-9009378 ( R-HSA-9018519 ) R-HSA-9009378 Reaction Name: Estrogen-responsive CCND1 gene expression See in Reactome R-HSA-8952419 ( R-HSA-8941858 ) R-HSA-8952419 Reaction Name: SMURFs ubiquitinate RUNX3 See in Reactome R-HSA-6782224 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782224 Reaction Name: 3' incision by ERCC5 (XPG) in TC-NER See in Reactome R-HSA-8936979 ( R-HSA-8936459 ) R-HSA-8936979 Reaction Name: RUNX1 and GATA1 bind the promoter of the THBS1 gene See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-3215144 ( R-HSA-6804114 ) R-HSA-3215144 Reaction Name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription See in Reactome R-HSA-8951966 ( R-HSA-8951936 ) R-HSA-8951966 Reaction Name: EP300 acetylates RUNX3 See in Reactome R-HSA-9008271 ( R-HSA-9018519 ) R-HSA-9008271 Reaction Name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter See in Reactome R-HSA-9011941 ( R-HSA-9018519 ) R-HSA-9011941 Reaction Name: Estrogen-responsive BCL2 gene expression See in Reactome R-HSA-2976563 ( R-HSA-2197563 ) R-HSA-2976563 Reaction Name: NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter See in Reactome R-HSA-5663273 ( R-HSA-400253 ) R-HSA-5663273 Reaction Name: RORA, EP300, PPARGC1A bind NR1D1 gene See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-6782141 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-6782141 Reaction Name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-8937037 ( R-HSA-8936459 ) R-HSA-8937037 Reaction Name: RUNX1 and GATA1 bind the promoter of the MIR27A gene See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-9617735 ( R-HSA-9617629 ) R-HSA-9617735 Reaction Name: TXN disrupts FOXO4 complex with EP300 See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-9018497 ( R-HSA-9018519 ) R-HSA-9018497 Reaction Name: Estrogen-responsive TFF3 gene expression See in Reactome R-HSA-8936995 ( R-HSA-8936459 ) R-HSA-8936995 Reaction Name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 See in Reactome R-HSA-9684118 ( R-HSA-6781827; R-HSA-6782135 ) R-HSA-9684118 Reaction Name: ERCC3-facilitated RNA Pol II backtracking in TC-NER See in Reactome R-HSA-6804242 ( R-HSA-6804760 ) R-HSA-6804242 Reaction Name: TP53 binds the complex of JMY, EP300 and TTC5 See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-3222093 ( R-HSA-6804758 ) R-HSA-3222093 Reaction Name: BRD7 binds TP53 and EP300 See in Reactome
MONDO:0030059	CDK19	Q9BWU1	2.7.11.22	R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Metabolism Developmental Biology	R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome
MONDO:0032897	CDK8	P49336	2.7.11.22 2.7.11.23	R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2173796 R-HSA-2173796 Reactome Name: SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription See in Reactome	R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-170834 R-HSA-170834 Reactome Name: Signaling by TGF-beta Receptor Complex See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-9006936 R-HSA-9006936 Reactome Name: Signaling by TGFB family members See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-2173793 R-HSA-2173793 Reactome Name: Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Signal Transduction Developmental Biology	R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-212352 ( R-HSA-212436 ) R-HSA-212352 Reaction Name: Formation of ARC coactivator complex See in Reactome R-HSA-212380 ( R-HSA-212436 ) R-HSA-212380 Reaction Name: Formation of TRAP coactivator complex See in Reactome R-HSA-212432 ( R-HSA-212436 ) R-HSA-212432 Reaction Name: Formation of DRIP coactivator complex See in Reactome R-HSA-2176475 ( R-HSA-212436; R-HSA-2173796 ) R-HSA-2176475 Reaction Name: Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome

Number of enzymes:	10
Number of disease:	29
Number of reactomes:	84
Number of reactions:	329

Search summary (Reactome ID: R-HSA-381340)

Search results (Reactome ID: R-HSA-381340)

MONDO:0005012

R-HSA-2559585

R-HSA-2559580

R-HSA-2559582

R-HSA-381340

R-HSA-912446

R-HSA-9616222

R-HSA-8878166

R-HSA-8849470

R-HSA-69231

R-HSA-75815

R-HSA-3214858

R-HSA-187577

R-HSA-8848021

R-HSA-2559583

R-HSA-9006927

R-HSA-1640170

R-HSA-1266738

R-HSA-73857

R-HSA-212436

R-HSA-74160

R-HSA-2262752

R-HSA-69236

R-HSA-69278

R-HSA-1474165

R-HSA-453279

R-HSA-8953897

R-HSA-3247509

R-HSA-69656

R-HSA-69206

R-HSA-69202

R-HSA-69242

R-HSA-1500620

R-HSA-4839726

R-HSA-162582

R-HSA-1226094

R-HSA-1226095

R-HSA-182594

R-HSA-3215385

R-HSA-3215426

R-HSA-5205799

R-HSA-5205861

R-HSA-5216234

R-HSA-560510

R-HSA-5661117

R-HSA-69227

R-HSA-75820

R-HSA-75822

R-HSA-8848414

R-HSA-8848436

R-HSA-8941895

R-HSA-8941915

R-HSA-8942607

R-HSA-8942803

R-HSA-8942836

R-HSA-9008412

R-HSA-9018017

R-HSA-912429

R-HSA-912458

R-HSA-912496

R-HSA-912503

R-HSA-9624112

R-HSA-9754130

MONDO:0005061

R-HSA-2559585

R-HSA-2559580

R-HSA-2559582

R-HSA-381340

R-HSA-912446

R-HSA-9616222

R-HSA-8878166

R-HSA-8849470

R-HSA-69231

R-HSA-75815

R-HSA-3214858

R-HSA-187577

R-HSA-8848021

R-HSA-2559583