DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-380612)

Number of enzymes:	2
Number of disease:	3
Number of reactomes:	7
Number of reactions:	7

Search results (Reactome ID: R-HSA-380612)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010379	MAOA	P21397	1.4.3.4	R-HSA-379398 R-HSA-379398 Reactome Name: Enzymatic degradation of Dopamine by monoamine oxidase See in Reactome R-HSA-380612 R-HSA-380612 Reactome Name: Metabolism of serotonin See in Reactome R-HSA-379397 R-HSA-379397 Reactome Name: Enzymatic degradation of dopamine by COMT See in Reactome R-HSA-181430 R-HSA-181430 Reactome Name: Norepinephrine Neurotransmitter Release Cycle See in Reactome R-HSA-6785807 R-HSA-6785807 Reactome Name: Interleukin-4 and Interleukin-13 signaling See in Reactome R-HSA-141333 R-HSA-141333 Reactome Name: Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB See in Reactome	R-HSA-380615 R-HSA-380615 Reactome Name: Serotonin clearance from the synaptic cleft See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-379401 R-HSA-379401 Reactome Name: Dopamine clearance from the synaptic cleft See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-140179 R-HSA-140179 Reactome Name: Amine Oxidase reactions See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-112310 R-HSA-112310 Reactome Name: Neurotransmitter release cycle See in Reactome R-HSA-112311 R-HSA-112311 Reactome Name: Neurotransmitter clearance See in Reactome	Immune System Metabolism Neuronal System	R-HSA-141186 ( R-HSA-141333; R-HSA-380612 ) R-HSA-141186 Reaction Name: MAOA:FAD oxidatively deaminates of 5HT See in Reactome R-HSA-374909 ( R-HSA-181430 ) R-HSA-374909 Reaction Name: Metabolism of Noradrenaline See in Reactome R-HSA-379382 ( R-HSA-379398 ) R-HSA-379382 Reaction Name: MAOA:FAD deaminates DA to DOPAC See in Reactome R-HSA-379395 ( R-HSA-379397 ) R-HSA-379395 Reaction Name: MAOA:FAD deaminates 3MT to HVA See in Reactome R-HSA-6797271 ( R-HSA-6785807 ) R-HSA-6797271 Reaction Name: Expression of MAOA See in Reactome
MONDO:0012454	ALDH2	P05091	1.2.1.3	R-HSA-380612 R-HSA-380612 Reactome Name: Metabolism of serotonin See in Reactome R-HSA-71384 R-HSA-71384 Reactome Name: Ethanol oxidation See in Reactome	R-HSA-380615 R-HSA-380615 Reactome Name: Serotonin clearance from the synaptic cleft See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-112311 R-HSA-112311 Reactome Name: Neurotransmitter clearance See in Reactome	Metabolism Neuronal System	R-HSA-380608 ( R-HSA-380612 ) R-HSA-380608 Reaction Name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid See in Reactome R-HSA-71723 ( R-HSA-71384 ) R-HSA-71723 Reaction Name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] See in Reactome
MONDO:0030894	ALDH2	P05091	1.2.1.3	R-HSA-380612 R-HSA-380612 Reactome Name: Metabolism of serotonin See in Reactome R-HSA-71384 R-HSA-71384 Reactome Name: Ethanol oxidation See in Reactome	R-HSA-380615 R-HSA-380615 Reactome Name: Serotonin clearance from the synaptic cleft See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-112311 R-HSA-112311 Reactome Name: Neurotransmitter clearance See in Reactome	Metabolism Neuronal System	R-HSA-380608 ( R-HSA-380612 ) R-HSA-380608 Reaction Name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid See in Reactome R-HSA-71723 ( R-HSA-71384 ) R-HSA-71723 Reaction Name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] See in Reactome