MONDO:0002135 |
KARS1 |
Q15046 |
6.1.1.6
2.7.7.-
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
R-HSA-379716
R-HSA-2408522
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism
Metabolism of proteins
|
R-HSA-2408546
(
R-HSA-2408522
)
R-HSA-2408546
Reaction Name: tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex
See in Reactome
R-HSA-379861
(
R-HSA-379716
)
R-HSA-379861
Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
R-HSA-379865
(
R-HSA-379716
)
R-HSA-379865
Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
See in Reactome
R-HSA-379867
(
R-HSA-379716
)
R-HSA-379867
Reaction Name: aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
See in Reactome
R-HSA-379893
(
R-HSA-379716
)
R-HSA-379893
Reaction Name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
See in Reactome
R-HSA-379974
(
R-HSA-379716
)
R-HSA-379974
Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
See in Reactome
R-HSA-379982
(
R-HSA-379716
)
R-HSA-379982
Reaction Name: glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate
See in Reactome
R-HSA-379993
(
R-HSA-379716
)
R-HSA-379993
Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
See in Reactome
R-HSA-379994
(
R-HSA-379716
)
R-HSA-379994
Reaction Name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
See in Reactome
R-HSA-380008
(
R-HSA-379716
)
R-HSA-380008
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
R-HSA-380233
(
R-HSA-379726
)
R-HSA-380233
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
|
MONDO:0004675 |
MONDO:0004675
Disease Name: mitochondrial encephalomyopathy
All associated enzymes in DAR:
FARS2
. The disease is also associated to other non-enzyme proteins (not in DAR).
FARS2 |
O95363 |
6.1.1.20
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380203
(
R-HSA-379726
)
R-HSA-380203
Reaction Name: phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate
See in Reactome
|
MONDO:0008779 |
MONDO:0008779
Disease Name: arthrogryposis
All associated enzymes in DAR:
GBE1
EARS2
ASAH1
ATP2B3
EARS2 |
Q5JPH6 |
6.1.1.17
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380216
(
R-HSA-379726
)
R-HSA-380216
Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
|
MONDO:0008939 |
RARS2 |
Q5T160 |
6.1.1.19
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380224
(
R-HSA-379726
)
R-HSA-380224
Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
See in Reactome
|
MONDO:0009096 |
AARS2 |
Q5JTZ9 |
6.1.1.7
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380177
(
R-HSA-379726
)
R-HSA-380177
Reaction Name: alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate
See in Reactome
|
MONDO:0009637 |
LARS2 |
Q15031 |
6.1.1.4
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380200
(
R-HSA-379726
)
R-HSA-380200
Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
See in Reactome
|
MONDO:0011091 |
GARS1 |
P41250 |
2.7.7.-
6.1.1.14
|
R-HSA-379716
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-379724
R-HSA-392499
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380048
(
R-HSA-379716
)
R-HSA-380048
Reaction Name: glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate
See in Reactome
R-HSA-380240
(
R-HSA-379726
)
R-HSA-380240
Reaction Name: glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate
See in Reactome
|
MONDO:0012622 |
DARS2 |
Q6PI48 |
6.1.1.12
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380229
(
R-HSA-379726
)
R-HSA-380229
Reaction Name: aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
See in Reactome
|
MONDO:0012664 |
MARS2 |
Q96GW9 |
6.1.1.10
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380157
(
R-HSA-379726
)
R-HSA-380157
Reaction Name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
See in Reactome
|
MONDO:0012683 |
RARS2 |
Q5T160 |
6.1.1.19
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380224
(
R-HSA-379726
)
R-HSA-380224
Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
See in Reactome
|
MONDO:0013307 |
YARS2 |
Q9Y2Z4 |
6.1.1.1
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380170
(
R-HSA-379726
)
R-HSA-380170
Reaction Name: tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate
See in Reactome
|
MONDO:0013338 |
KARS1 |
Q15046 |
6.1.1.6
2.7.7.-
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
R-HSA-379716
R-HSA-2408522
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism
Metabolism of proteins
|
R-HSA-2408546
(
R-HSA-2408522
)
R-HSA-2408546
Reaction Name: tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex
See in Reactome
R-HSA-379861
(
R-HSA-379716
)
R-HSA-379861
Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
R-HSA-379865
(
R-HSA-379716
)
R-HSA-379865
Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
See in Reactome
R-HSA-379867
(
R-HSA-379716
)
R-HSA-379867
Reaction Name: aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
See in Reactome
R-HSA-379893
(
R-HSA-379716
)
R-HSA-379893
Reaction Name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
See in Reactome
R-HSA-379974
(
R-HSA-379716
)
R-HSA-379974
Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
See in Reactome
R-HSA-379982
(
R-HSA-379716
)
R-HSA-379982
Reaction Name: glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate
See in Reactome
R-HSA-379993
(
R-HSA-379716
)
R-HSA-379993
Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
See in Reactome
R-HSA-379994
(
R-HSA-379716
)
R-HSA-379994
Reaction Name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
See in Reactome
R-HSA-380008
(
R-HSA-379716
)
R-HSA-380008
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
R-HSA-380233
(
R-HSA-379726
)
R-HSA-380233
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
|
MONDO:0013458 |
SARS2 |
Q9NP81 |
6.1.1.11
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380239
(
R-HSA-379726
)
R-HSA-380239
Reaction Name: serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate
See in Reactome
|
MONDO:0013489 |
KARS1 |
Q15046 |
6.1.1.6
2.7.7.-
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
R-HSA-379716
R-HSA-2408522
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism
Metabolism of proteins
|
R-HSA-2408546
(
R-HSA-2408522
)
R-HSA-2408546
Reaction Name: tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex
See in Reactome
R-HSA-379861
(
R-HSA-379716
)
R-HSA-379861
Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
R-HSA-379865
(
R-HSA-379716
)
R-HSA-379865
Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
See in Reactome
R-HSA-379867
(
R-HSA-379716
)
R-HSA-379867
Reaction Name: aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
See in Reactome
R-HSA-379893
(
R-HSA-379716
)
R-HSA-379893
Reaction Name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
See in Reactome
R-HSA-379974
(
R-HSA-379716
)
R-HSA-379974
Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
See in Reactome
R-HSA-379982
(
R-HSA-379716
)
R-HSA-379982
Reaction Name: glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate
See in Reactome
R-HSA-379993
(
R-HSA-379716
)
R-HSA-379993
Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
See in Reactome
R-HSA-379994
(
R-HSA-379716
)
R-HSA-379994
Reaction Name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
See in Reactome
R-HSA-380008
(
R-HSA-379716
)
R-HSA-380008
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
R-HSA-380233
(
R-HSA-379726
)
R-HSA-380233
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
|
MONDO:0013570 |
AARS2 |
Q5JTZ9 |
6.1.1.7
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380177
(
R-HSA-379726
)
R-HSA-380177
Reaction Name: alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate
See in Reactome
|
MONDO:0013971 |
EARS2 |
Q5JPH6 |
6.1.1.17
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380216
(
R-HSA-379726
)
R-HSA-380216
Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
|
MONDO:0013972 |
HARS2 |
P49590 |
6.1.1.21
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380234
(
R-HSA-379726
)
R-HSA-380234
Reaction Name: histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate
See in Reactome
|
MONDO:0013986 |
FARS2 |
O95363 |
6.1.1.20
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380203
(
R-HSA-379726
)
R-HSA-380203
Reaction Name: phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014126 |
LARS2 |
Q15031 |
6.1.1.4
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380200
(
R-HSA-379726
)
R-HSA-380200
Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014335 |
QARS1 |
P47897 |
6.1.1.18
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
R-HSA-379716
R-HSA-2408522
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism
Metabolism of proteins
|
R-HSA-2408546
(
R-HSA-2408522
)
R-HSA-2408546
Reaction Name: tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex
See in Reactome
R-HSA-379861
(
R-HSA-379716
)
R-HSA-379861
Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
R-HSA-379865
(
R-HSA-379716
)
R-HSA-379865
Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
See in Reactome
R-HSA-379867
(
R-HSA-379716
)
R-HSA-379867
Reaction Name: aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
See in Reactome
R-HSA-379893
(
R-HSA-379716
)
R-HSA-379893
Reaction Name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
See in Reactome
R-HSA-379974
(
R-HSA-379716
)
R-HSA-379974
Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
See in Reactome
R-HSA-379982
(
R-HSA-379716
)
R-HSA-379982
Reaction Name: glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate
See in Reactome
R-HSA-379993
(
R-HSA-379716
)
R-HSA-379993
Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
See in Reactome
R-HSA-379994
(
R-HSA-379716
)
R-HSA-379994
Reaction Name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
See in Reactome
R-HSA-380008
(
R-HSA-379716
)
R-HSA-380008
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
R-HSA-380241
(
R-HSA-379726
)
R-HSA-380241
Reaction Name: glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014387 |
AARS2 |
Q5JTZ9 |
6.1.1.7
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380177
(
R-HSA-379726
)
R-HSA-380177
Reaction Name: alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014397 |
VARS2 |
Q5ST30 |
6.1.1.9
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380199
(
R-HSA-379726
)
R-HSA-380199
Reaction Name: valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014398 |
TARS2 |
Q9BW92 |
6.1.1.3
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380201
(
R-HSA-379726
)
R-HSA-380201
Reaction Name: threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014455 |
IARS2 |
Q9NSE4 |
6.1.1.5
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380176
(
R-HSA-379726
)
R-HSA-380176
Reaction Name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014547 |
NARS2 |
Q96I59 |
6.1.1.22
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380227
(
R-HSA-379726
)
R-HSA-380227
Reaction Name: asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014636 |
MARS2 |
Q96GW9 |
6.1.1.10
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380157
(
R-HSA-379726
)
R-HSA-380157
Reaction Name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014728 |
CARS2 |
Q9HA77 |
6.1.1.16
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380158
(
R-HSA-379726
)
R-HSA-380158
Reaction Name: cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014869 |
LARS2 |
Q15031 |
6.1.1.4
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380200
(
R-HSA-379726
)
R-HSA-380200
Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014882 |
FARS2 |
O95363 |
6.1.1.20
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380203
(
R-HSA-379726
)
R-HSA-380203
Reaction Name: phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate
See in Reactome
|
MONDO:0014973 |
PPA2 |
Q9H2U2 |
3.6.1.1
|
R-HSA-71737
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-1430728
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism
Metabolism of proteins
|
R-HSA-449937
(
R-HSA-379726;
R-HSA-71737
)
R-HSA-449937
Reaction Name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial]
See in Reactome
|
MONDO:0014974 |
PPA2 |
Q9H2U2 |
3.6.1.1
|
R-HSA-71737
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-1430728
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism
Metabolism of proteins
|
R-HSA-449937
(
R-HSA-379726;
R-HSA-71737
)
R-HSA-449937
Reaction Name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial]
See in Reactome
|
MONDO:0015168 |
EARS2 |
Q5JPH6 |
6.1.1.17
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380216
(
R-HSA-379726
)
R-HSA-380216
Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
|
MONDO:0015353 |
GARS1 |
P41250 |
2.7.7.-
6.1.1.14
|
R-HSA-379716
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-379724
R-HSA-392499
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380048
(
R-HSA-379716
)
R-HSA-380048
Reaction Name: glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate
See in Reactome
R-HSA-380240
(
R-HSA-379726
)
R-HSA-380240
Reaction Name: glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate
See in Reactome
|
MONDO:0016392 |
RARS2 |
Q5T160 |
6.1.1.19
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380224
(
R-HSA-379726
)
R-HSA-380224
Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
See in Reactome
|
MONDO:0018494 |
QARS1 |
P47897 |
6.1.1.18
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
R-HSA-379716
R-HSA-2408522
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism
Metabolism of proteins
|
R-HSA-2408546
(
R-HSA-2408522
)
R-HSA-2408546
Reaction Name: tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex
See in Reactome
R-HSA-379861
(
R-HSA-379716
)
R-HSA-379861
Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
R-HSA-379865
(
R-HSA-379716
)
R-HSA-379865
Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
See in Reactome
R-HSA-379867
(
R-HSA-379716
)
R-HSA-379867
Reaction Name: aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
See in Reactome
R-HSA-379893
(
R-HSA-379716
)
R-HSA-379893
Reaction Name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
See in Reactome
R-HSA-379974
(
R-HSA-379716
)
R-HSA-379974
Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
See in Reactome
R-HSA-379982
(
R-HSA-379716
)
R-HSA-379982
Reaction Name: glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate
See in Reactome
R-HSA-379993
(
R-HSA-379716
)
R-HSA-379993
Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
See in Reactome
R-HSA-379994
(
R-HSA-379716
)
R-HSA-379994
Reaction Name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
See in Reactome
R-HSA-380008
(
R-HSA-379716
)
R-HSA-380008
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
R-HSA-380241
(
R-HSA-379726
)
R-HSA-380241
Reaction Name: glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
|
MONDO:0018614 |
PARS2 |
Q7L3T8 |
6.1.1.15
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380198
(
R-HSA-379726
)
R-HSA-380198
Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
See in Reactome
|
MONDO:0020678 |
HARS2 |
P49590 |
6.1.1.21
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380234
(
R-HSA-379726
)
R-HSA-380234
Reaction Name: histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate
See in Reactome
|
MONDO:0030893 |
KARS1 |
Q15046 |
6.1.1.6
2.7.7.-
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
R-HSA-379716
R-HSA-2408522
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism
Metabolism of proteins
|
R-HSA-2408546
(
R-HSA-2408522
)
R-HSA-2408546
Reaction Name: tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex
See in Reactome
R-HSA-379861
(
R-HSA-379716
)
R-HSA-379861
Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
R-HSA-379865
(
R-HSA-379716
)
R-HSA-379865
Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
See in Reactome
R-HSA-379867
(
R-HSA-379716
)
R-HSA-379867
Reaction Name: aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
See in Reactome
R-HSA-379893
(
R-HSA-379716
)
R-HSA-379893
Reaction Name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
See in Reactome
R-HSA-379974
(
R-HSA-379716
)
R-HSA-379974
Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
See in Reactome
R-HSA-379982
(
R-HSA-379716
)
R-HSA-379982
Reaction Name: glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate
See in Reactome
R-HSA-379993
(
R-HSA-379716
)
R-HSA-379993
Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
See in Reactome
R-HSA-379994
(
R-HSA-379716
)
R-HSA-379994
Reaction Name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
See in Reactome
R-HSA-380008
(
R-HSA-379716
)
R-HSA-380008
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
R-HSA-380233
(
R-HSA-379726
)
R-HSA-380233
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
|
MONDO:0030967 |
KARS1 |
Q15046 |
6.1.1.6
2.7.7.-
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
R-HSA-379716
R-HSA-2408522
|
R-HSA-71291
R-HSA-71291
Reactome Name: Metabolism of amino acids and derivatives
See in Reactome
R-HSA-1430728
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism
Metabolism of proteins
|
R-HSA-2408546
(
R-HSA-2408522
)
R-HSA-2408546
Reaction Name: tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex
See in Reactome
R-HSA-379861
(
R-HSA-379716
)
R-HSA-379861
Reaction Name: glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate
See in Reactome
R-HSA-379865
(
R-HSA-379716
)
R-HSA-379865
Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
See in Reactome
R-HSA-379867
(
R-HSA-379716
)
R-HSA-379867
Reaction Name: aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate
See in Reactome
R-HSA-379893
(
R-HSA-379716
)
R-HSA-379893
Reaction Name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
See in Reactome
R-HSA-379974
(
R-HSA-379716
)
R-HSA-379974
Reaction Name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate
See in Reactome
R-HSA-379982
(
R-HSA-379716
)
R-HSA-379982
Reaction Name: glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate
See in Reactome
R-HSA-379993
(
R-HSA-379716
)
R-HSA-379993
Reaction Name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate
See in Reactome
R-HSA-379994
(
R-HSA-379716
)
R-HSA-379994
Reaction Name: methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate
See in Reactome
R-HSA-380008
(
R-HSA-379716
)
R-HSA-380008
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
R-HSA-380233
(
R-HSA-379726
)
R-HSA-380233
Reaction Name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
See in Reactome
|
MONDO:0032749 |
NARS2 |
Q96I59 |
6.1.1.22
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380227
(
R-HSA-379726
)
R-HSA-380227
Reaction Name: asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate
See in Reactome
|
MONDO:0032752 |
PARS2 |
Q7L3T8 |
6.1.1.15
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380198
(
R-HSA-379726
)
R-HSA-380198
Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate
See in Reactome
|
MONDO:0033621 |
GARS1 |
P41250 |
2.7.7.-
6.1.1.14
|
R-HSA-379716
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-379724
R-HSA-392499
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380048
(
R-HSA-379716
)
R-HSA-380048
Reaction Name: glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate
See in Reactome
R-HSA-380240
(
R-HSA-379726
)
R-HSA-380240
Reaction Name: glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate
See in Reactome
|
MONDO:0060578 |
WARS2 |
Q9UGM6 |
6.1.1.2
|
R-HSA-379726
R-HSA-379726
Reactome Name: Mitochondrial tRNA aminoacylation
See in Reactome
|
R-HSA-392499
R-HSA-379724
R-HSA-72766
|
Metabolism of proteins
|
R-HSA-380222
(
R-HSA-379726
)
R-HSA-380222
Reaction Name: tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate
See in Reactome
|