DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-379397)

Number of enzymes:	3
Number of disease:	3
Number of reactomes:	7
Number of reactions:	10

Search results (Reactome ID: R-HSA-379397)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0005090	COMT	P21964	2.1.1.6	R-HSA-379398 R-HSA-379398 Reactome Name: Enzymatic degradation of Dopamine by monoamine oxidase See in Reactome R-HSA-379397 R-HSA-379397 Reactome Name: Enzymatic degradation of dopamine by COMT See in Reactome R-HSA-156581 R-HSA-156581 Reactome Name: Methylation See in Reactome	R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-379401 R-HSA-379401 Reactome Name: Dopamine clearance from the synaptic cleft See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-112311 R-HSA-112311 Reactome Name: Neurotransmitter clearance See in Reactome	Metabolism Neuronal System	R-HSA-175983 ( R-HSA-156581 ) R-HSA-175983 Reaction Name: COMT transfer CH3 from AdoMet to 3,4DHBNZ See in Reactome R-HSA-379387 ( R-HSA-379397 ) R-HSA-379387 Reaction Name: COMT transfers Met to DA to form 3MT See in Reactome R-HSA-379464 ( R-HSA-379398 ) R-HSA-379464 Reaction Name: COMT transfers Met to DOPAC to form HVA See in Reactome R-HSA-9679775 ( R-HSA-379397 ) R-HSA-9679775 Reaction Name: COMT binds COMT Inhibitors See in Reactome
MONDO:0010379	MAOA	P21397	1.4.3.4	R-HSA-379398 R-HSA-379398 Reactome Name: Enzymatic degradation of Dopamine by monoamine oxidase See in Reactome R-HSA-380612 R-HSA-380612 Reactome Name: Metabolism of serotonin See in Reactome R-HSA-379397 R-HSA-379397 Reactome Name: Enzymatic degradation of dopamine by COMT See in Reactome R-HSA-181430 R-HSA-181430 Reactome Name: Norepinephrine Neurotransmitter Release Cycle See in Reactome R-HSA-6785807 R-HSA-6785807 Reactome Name: Interleukin-4 and Interleukin-13 signaling See in Reactome R-HSA-141333 R-HSA-141333 Reactome Name: Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB See in Reactome	R-HSA-380615 R-HSA-380615 Reactome Name: Serotonin clearance from the synaptic cleft See in Reactome R-HSA-449147 R-HSA-449147 Reactome Name: Signaling by Interleukins See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-379401 R-HSA-379401 Reactome Name: Dopamine clearance from the synaptic cleft See in Reactome R-HSA-1280215 R-HSA-1280215 Reactome Name: Cytokine Signaling in Immune system See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-140179 R-HSA-140179 Reactome Name: Amine Oxidase reactions See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-112310 R-HSA-112310 Reactome Name: Neurotransmitter release cycle See in Reactome R-HSA-112311 R-HSA-112311 Reactome Name: Neurotransmitter clearance See in Reactome	Immune System Metabolism Neuronal System	R-HSA-141186 ( R-HSA-141333; R-HSA-380612 ) R-HSA-141186 Reaction Name: MAOA:FAD oxidatively deaminates of 5HT See in Reactome R-HSA-374909 ( R-HSA-181430 ) R-HSA-374909 Reaction Name: Metabolism of Noradrenaline See in Reactome R-HSA-379382 ( R-HSA-379398 ) R-HSA-379382 Reaction Name: MAOA:FAD deaminates DA to DOPAC See in Reactome R-HSA-379395 ( R-HSA-379397 ) R-HSA-379395 Reaction Name: MAOA:FAD deaminates 3MT to HVA See in Reactome R-HSA-6797271 ( R-HSA-6785807 ) R-HSA-6797271 Reaction Name: Expression of MAOA See in Reactome
MONDO:0012670	TOMT	Q8WZ04	2.1.1.6	R-HSA-379397 R-HSA-379397 Reactome Name: Enzymatic degradation of dopamine by COMT See in Reactome	R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-379401 R-HSA-379401 Reactome Name: Dopamine clearance from the synaptic cleft See in Reactome R-HSA-112311 R-HSA-112311 Reactome Name: Neurotransmitter clearance See in Reactome	Neuronal System	R-HSA-8955010 ( R-HSA-379397 ) R-HSA-8955010 Reaction Name: LRTOMT transfers Met to DA, forming 3MT See in Reactome