MONDO:0008214 |
LBR |
Q14739 |
1.3.1.70
|
R-HSA-191273
R-HSA-9013106
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-8980692
R-HSA-9013408
R-HSA-9013423
R-HSA-9013404
R-HSA-9013405
R-HSA-9013149
R-HSA-9013148
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9012999
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-212436
R-HSA-74160
R-HSA-194315
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-556833
R-HSA-69278
R-HSA-1430728
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-1640170
R-HSA-8957322
R-HSA-162582
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Cell Cycle
Signal Transduction
|
R-HSA-194674
(
R-HSA-191273
)
R-HSA-194674
Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]
See in Reactome
R-HSA-9013004
(
R-HSA-8980692
)
R-HSA-9013004
Reaction Name: RHOA binds effectors at the ER membrane
See in Reactome
R-HSA-9013438
(
R-HSA-9013405
)
R-HSA-9013438
Reaction Name: RHOD binds effectors at the endosome membrane
See in Reactome
R-HSA-9014467
(
R-HSA-9013408
)
R-HSA-9014467
Reaction Name: RHOG binds effectors at the ER membrane
See in Reactome
R-HSA-9018594
(
R-HSA-9022692
)
R-HSA-9624798
(
R-HSA-2995383
)
R-HSA-9624800
(
R-HSA-2995383
)
R-HSA-9691174
(
R-HSA-9013149
)
R-HSA-9691174
Reaction Name: RAC1 binds effectors at the ER membrane
See in Reactome
R-HSA-9692809
(
R-HSA-9013148
)
R-HSA-9692809
Reaction Name: CDC42 binds effectors at the ER membrane
See in Reactome
R-HSA-9714361
(
R-HSA-9013106
)
R-HSA-9714361
Reaction Name: RHOC activates endoplasmic reticulum effectors
See in Reactome
R-HSA-9714481
(
R-HSA-9013404
)
R-HSA-9714481
Reaction Name: RAC2 binds effectors at the ER membrane
See in Reactome
R-HSA-9714691
(
R-HSA-9013423
)
|
MONDO:0008974 |
LBR |
Q14739 |
1.3.1.70
|
R-HSA-191273
R-HSA-9013106
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-8980692
R-HSA-9013408
R-HSA-9013423
R-HSA-9013404
R-HSA-9013405
R-HSA-9013149
R-HSA-9013148
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9012999
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-212436
R-HSA-74160
R-HSA-194315
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-556833
R-HSA-69278
R-HSA-1430728
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-1640170
R-HSA-8957322
R-HSA-162582
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Cell Cycle
Signal Transduction
|
R-HSA-194674
(
R-HSA-191273
)
R-HSA-194674
Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]
See in Reactome
R-HSA-9013004
(
R-HSA-8980692
)
R-HSA-9013004
Reaction Name: RHOA binds effectors at the ER membrane
See in Reactome
R-HSA-9013438
(
R-HSA-9013405
)
R-HSA-9013438
Reaction Name: RHOD binds effectors at the endosome membrane
See in Reactome
R-HSA-9014467
(
R-HSA-9013408
)
R-HSA-9014467
Reaction Name: RHOG binds effectors at the ER membrane
See in Reactome
R-HSA-9018594
(
R-HSA-9022692
)
R-HSA-9624798
(
R-HSA-2995383
)
R-HSA-9624800
(
R-HSA-2995383
)
R-HSA-9691174
(
R-HSA-9013149
)
R-HSA-9691174
Reaction Name: RAC1 binds effectors at the ER membrane
See in Reactome
R-HSA-9692809
(
R-HSA-9013148
)
R-HSA-9692809
Reaction Name: CDC42 binds effectors at the ER membrane
See in Reactome
R-HSA-9714361
(
R-HSA-9013106
)
R-HSA-9714361
Reaction Name: RHOC activates endoplasmic reticulum effectors
See in Reactome
R-HSA-9714481
(
R-HSA-9013404
)
R-HSA-9714481
Reaction Name: RAC2 binds effectors at the ER membrane
See in Reactome
R-HSA-9714691
(
R-HSA-9013423
)
|
MONDO:0011866 |
VRK1 |
Q99986 |
2.7.11.1
|
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-2980766
|
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-69278
R-HSA-68882
R-HSA-1640170
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-68875
|
Cell Cycle
|
R-HSA-2993898
(
R-HSA-2980766
)
R-HSA-2995389
(
R-HSA-2995383
)
|
MONDO:0013276 |
LBR |
Q14739 |
1.3.1.70
|
R-HSA-191273
R-HSA-9013106
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-8980692
R-HSA-9013408
R-HSA-9013423
R-HSA-9013404
R-HSA-9013405
R-HSA-9013149
R-HSA-9013148
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9012999
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-212436
R-HSA-74160
R-HSA-194315
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-556833
R-HSA-69278
R-HSA-1430728
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-1640170
R-HSA-8957322
R-HSA-162582
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Cell Cycle
Signal Transduction
|
R-HSA-194674
(
R-HSA-191273
)
R-HSA-194674
Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]
See in Reactome
R-HSA-9013004
(
R-HSA-8980692
)
R-HSA-9013004
Reaction Name: RHOA binds effectors at the ER membrane
See in Reactome
R-HSA-9013438
(
R-HSA-9013405
)
R-HSA-9013438
Reaction Name: RHOD binds effectors at the endosome membrane
See in Reactome
R-HSA-9014467
(
R-HSA-9013408
)
R-HSA-9014467
Reaction Name: RHOG binds effectors at the ER membrane
See in Reactome
R-HSA-9018594
(
R-HSA-9022692
)
R-HSA-9624798
(
R-HSA-2995383
)
R-HSA-9624800
(
R-HSA-2995383
)
R-HSA-9691174
(
R-HSA-9013149
)
R-HSA-9691174
Reaction Name: RAC1 binds effectors at the ER membrane
See in Reactome
R-HSA-9692809
(
R-HSA-9013148
)
R-HSA-9692809
Reaction Name: CDC42 binds effectors at the ER membrane
See in Reactome
R-HSA-9714361
(
R-HSA-9013106
)
R-HSA-9714361
Reaction Name: RHOC activates endoplasmic reticulum effectors
See in Reactome
R-HSA-9714481
(
R-HSA-9013404
)
R-HSA-9714481
Reaction Name: RAC2 binds effectors at the ER membrane
See in Reactome
R-HSA-9714691
(
R-HSA-9013423
)
|
MONDO:0018507 |
VRK1 |
Q99986 |
2.7.11.1
|
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-2980766
|
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-69278
R-HSA-68882
R-HSA-1640170
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-68875
|
Cell Cycle
|
R-HSA-2993898
(
R-HSA-2980766
)
R-HSA-2995389
(
R-HSA-2995383
)
|
MONDO:0018663 |
LBR |
Q14739 |
1.3.1.70
|
R-HSA-191273
R-HSA-9013106
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-8980692
R-HSA-9013408
R-HSA-9013423
R-HSA-9013404
R-HSA-9013405
R-HSA-9013149
R-HSA-9013148
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9012999
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-212436
R-HSA-74160
R-HSA-194315
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-556833
R-HSA-69278
R-HSA-1430728
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-1640170
R-HSA-8957322
R-HSA-162582
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Cell Cycle
Signal Transduction
|
R-HSA-194674
(
R-HSA-191273
)
R-HSA-194674
Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]
See in Reactome
R-HSA-9013004
(
R-HSA-8980692
)
R-HSA-9013004
Reaction Name: RHOA binds effectors at the ER membrane
See in Reactome
R-HSA-9013438
(
R-HSA-9013405
)
R-HSA-9013438
Reaction Name: RHOD binds effectors at the endosome membrane
See in Reactome
R-HSA-9014467
(
R-HSA-9013408
)
R-HSA-9014467
Reaction Name: RHOG binds effectors at the ER membrane
See in Reactome
R-HSA-9018594
(
R-HSA-9022692
)
R-HSA-9624798
(
R-HSA-2995383
)
R-HSA-9624800
(
R-HSA-2995383
)
R-HSA-9691174
(
R-HSA-9013149
)
R-HSA-9691174
Reaction Name: RAC1 binds effectors at the ER membrane
See in Reactome
R-HSA-9692809
(
R-HSA-9013148
)
R-HSA-9692809
Reaction Name: CDC42 binds effectors at the ER membrane
See in Reactome
R-HSA-9714361
(
R-HSA-9013106
)
R-HSA-9714361
Reaction Name: RHOC activates endoplasmic reticulum effectors
See in Reactome
R-HSA-9714481
(
R-HSA-9013404
)
R-HSA-9714481
Reaction Name: RAC2 binds effectors at the ER membrane
See in Reactome
R-HSA-9714691
(
R-HSA-9013423
)
|
MONDO:0018770 |
MONDO:0018770
Disease Name: Jeune syndrome
OMIM id: OMIM:617088
Orphanet id: Orphanet:474
All associated enzymes in DAR:
LBR
. The disease is also associated to other non-enzyme proteins (not in DAR).
LBR |
Q14739 |
1.3.1.70
|
R-HSA-191273
R-HSA-9013106
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-9022692
R-HSA-9022692
Reactome Name: Regulation of MECP2 expression and activity
See in Reactome
R-HSA-8980692
R-HSA-9013408
R-HSA-9013423
R-HSA-9013404
R-HSA-9013405
R-HSA-9013149
R-HSA-9013148
|
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-9012999
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-68886
R-HSA-212436
R-HSA-74160
R-HSA-194315
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-556833
R-HSA-69278
R-HSA-1430728
R-HSA-68882
R-HSA-8986944
R-HSA-8986944
Reactome Name: Transcriptional Regulation by MECP2
See in Reactome
R-HSA-1640170
R-HSA-8957322
R-HSA-162582
R-HSA-73857
|
Gene expression (Transcription)
Metabolism
Cell Cycle
Signal Transduction
|
R-HSA-194674
(
R-HSA-191273
)
R-HSA-194674
Reaction Name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]
See in Reactome
R-HSA-9013004
(
R-HSA-8980692
)
R-HSA-9013004
Reaction Name: RHOA binds effectors at the ER membrane
See in Reactome
R-HSA-9013438
(
R-HSA-9013405
)
R-HSA-9013438
Reaction Name: RHOD binds effectors at the endosome membrane
See in Reactome
R-HSA-9014467
(
R-HSA-9013408
)
R-HSA-9014467
Reaction Name: RHOG binds effectors at the ER membrane
See in Reactome
R-HSA-9018594
(
R-HSA-9022692
)
R-HSA-9624798
(
R-HSA-2995383
)
R-HSA-9624800
(
R-HSA-2995383
)
R-HSA-9691174
(
R-HSA-9013149
)
R-HSA-9691174
Reaction Name: RAC1 binds effectors at the ER membrane
See in Reactome
R-HSA-9692809
(
R-HSA-9013148
)
R-HSA-9692809
Reaction Name: CDC42 binds effectors at the ER membrane
See in Reactome
R-HSA-9714361
(
R-HSA-9013106
)
R-HSA-9714361
Reaction Name: RHOC activates endoplasmic reticulum effectors
See in Reactome
R-HSA-9714481
(
R-HSA-9013404
)
R-HSA-9714481
Reaction Name: RAC2 binds effectors at the ER membrane
See in Reactome
R-HSA-9714691
(
R-HSA-9013423
)
|
MONDO:0032697 |
PPP2CA |
P67775 |
3.1.3.16
|
R-HSA-2467813
R-HSA-2467813
Reactome Name: Separation of Sister Chromatids
See in Reactome
R-HSA-198753
R-HSA-2995383
R-HSA-2995383
Reactome Name: Initiation of Nuclear Envelope (NE) Reformation
See in Reactome
R-HSA-4641262
R-HSA-4641262
Reactome Name: Disassembly of the destruction complex and recruitment of AXIN to the membrane
See in Reactome
R-HSA-5673000
R-HSA-180024
R-HSA-2500257
R-HSA-2500257
Reactome Name: Resolution of Sister Chromatid Cohesion
See in Reactome
R-HSA-2465910
R-HSA-2465910
Reactome Name: MASTL Facilitates Mitotic Progression
See in Reactome
R-HSA-9648025
R-HSA-9648025
Reactome Name: EML4 and NUDC in mitotic spindle formation
See in Reactome
R-HSA-389513
R-HSA-196299
R-HSA-196299
Reactome Name: Beta-catenin phosphorylation cascade
See in Reactome
R-HSA-69231
R-HSA-69231
Reactome Name: Cyclin D associated events in G1
See in Reactome
R-HSA-432142
R-HSA-113501
R-HSA-113501
Reactome Name: Inhibition of replication initiation of damaged DNA by RB1/E2F1
See in Reactome
R-HSA-141444
R-HSA-141444
Reactome Name: Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
See in Reactome
R-HSA-5663220
R-HSA-1295596
R-HSA-1295596
Reactome Name: Spry regulation of FGF signaling
See in Reactome
R-HSA-9634600
R-HSA-9634600
Reactome Name: Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
See in Reactome
R-HSA-6804757
R-HSA-6804757
Reactome Name: Regulation of TP53 Degradation
See in Reactome
R-HSA-163685
R-HSA-163685
Reactome Name: Integration of energy metabolism
See in Reactome
R-HSA-69273
R-HSA-69273
Reactome Name: Cyclin A/B1/B2 associated events during G2/M transition
See in Reactome
R-HSA-5675221
R-HSA-5675221
Reactome Name: Negative regulation of MAPK pathway
See in Reactome
R-HSA-163767
R-HSA-163767
Reactome Name: PP2A-mediated dephosphorylation of key metabolic factors
See in Reactome
R-HSA-195253
R-HSA-195253
Reactome Name: Degradation of beta-catenin by the destruction complex
See in Reactome
R-HSA-975957
R-HSA-975957
Reactome Name: Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
See in Reactome
R-HSA-6811558
R-HSA-6811558
Reactome Name: PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
See in Reactome
R-HSA-202670
R-HSA-68877
|
R-HSA-937061
R-HSA-937061
Reactome Name: TRIF(TICAM1)-mediated TLR4 signaling
See in Reactome
R-HSA-3700989
R-HSA-3700989
Reactome Name: Transcriptional Regulation by TP53
See in Reactome
R-HSA-975871
R-HSA-975871
Reactome Name: MyD88 cascade initiated on plasma membrane
See in Reactome
R-HSA-70326
R-HSA-449147
R-HSA-6806003
R-HSA-6806003
Reactome Name: Regulation of TP53 Expression and Degradation
See in Reactome
R-HSA-418594
R-HSA-181438
R-HSA-181438
Reactome Name: Toll Like Receptor 2 (TLR2) Cascade
See in Reactome
R-HSA-166016
R-HSA-166016
Reactome Name: Toll Like Receptor 4 (TLR4) Cascade
See in Reactome
R-HSA-194315
R-HSA-5654732
R-HSA-5654732
Reactome Name: Negative regulation of FGFR3 signaling
See in Reactome
R-HSA-1280215
R-HSA-1280215
Reactome Name: Cytokine Signaling in Immune system
See in Reactome
R-HSA-195258
R-HSA-9006925
R-HSA-9006925
Reactome Name: Intracellular signaling by second messengers
See in Reactome
R-HSA-1430728
R-HSA-1257604
R-HSA-1640170
R-HSA-5684996
R-HSA-1280218
R-HSA-5673001
R-HSA-199418
R-HSA-199418
Reactome Name: Negative regulation of the PI3K/AKT network
See in Reactome
R-HSA-450282
R-HSA-450282
Reactome Name: MAPK targets/ Nuclear events mediated by MAP kinases
See in Reactome
R-HSA-168142
R-HSA-168142
Reactome Name: Toll Like Receptor 10 (TLR10) Cascade
See in Reactome
R-HSA-71387
R-HSA-2555396
R-HSA-2555396
Reactome Name: Mitotic Metaphase and Anaphase
See in Reactome
R-HSA-212436
R-HSA-74160
R-HSA-168164
R-HSA-168164
Reactome Name: Toll Like Receptor 3 (TLR3) Cascade
See in Reactome
R-HSA-5654726
R-HSA-5654726
Reactome Name: Negative regulation of FGFR1 signaling
See in Reactome
R-HSA-5654727
R-HSA-5654727
Reactome Name: Negative regulation of FGFR2 signaling
See in Reactome
R-HSA-69620
R-HSA-69236
R-HSA-69278
R-HSA-198725
R-HSA-198725
Reactome Name: Nuclear Events (kinase and transcription factor activation)
See in Reactome
R-HSA-448424
R-HSA-418346
R-HSA-388396
R-HSA-166166
R-HSA-388841
R-HSA-388841
Reactome Name: Costimulation by the CD28 family
See in Reactome
R-HSA-73857
R-HSA-5654743
R-HSA-69275
R-HSA-5654741
R-HSA-453279
R-HSA-453279
Reactome Name: Mitotic G1 phase and G1/S transition
See in Reactome
R-HSA-168188
R-HSA-168188
Reactome Name: Toll Like Receptor TLR6:TLR2 Cascade
See in Reactome
R-HSA-168181
R-HSA-168181
Reactome Name: Toll Like Receptor 7/8 (TLR7/8) Cascade
See in Reactome
R-HSA-190236
R-HSA-141424
R-HSA-141424
Reactome Name: Amplification of signal from the kinetochores
See in Reactome
R-HSA-168256
R-HSA-8953854
R-HSA-168249
R-HSA-168179
R-HSA-168179
Reactome Name: Toll Like Receptor TLR1:TLR2 Cascade
See in Reactome
R-HSA-168138
R-HSA-168138
Reactome Name: Toll Like Receptor 9 (TLR9) Cascade
See in Reactome
R-HSA-453274
R-HSA-68886
R-HSA-70171
R-HSA-9006934
R-HSA-9006934
Reactome Name: Signaling by Receptor Tyrosine Kinases
See in Reactome
R-HSA-68882
R-HSA-2995410
R-HSA-2995410
Reactome Name: Nuclear Envelope (NE) Reassembly
See in Reactome
R-HSA-9716542
R-HSA-9716542
Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
See in Reactome
R-HSA-168898
R-HSA-187037
R-HSA-5633007
R-HSA-450294
R-HSA-195721
R-HSA-166520
R-HSA-372790
R-HSA-5654738
R-HSA-69206
R-HSA-5654736
R-HSA-111885
R-HSA-5654733
R-HSA-5654733
Reactome Name: Negative regulation of FGFR4 signaling
See in Reactome
R-HSA-168176
R-HSA-168176
Reactome Name: Toll Like Receptor 5 (TLR5) Cascade
See in Reactome
R-HSA-109582
R-HSA-975155
R-HSA-975155
Reactome Name: MyD88 dependent cascade initiated on endosome
See in Reactome
R-HSA-166058
R-HSA-166058
Reactome Name: MyD88:MAL(TIRAP) cascade initiated on plasma membrane
See in Reactome
R-HSA-975138
R-HSA-975138
Reactome Name: TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
See in Reactome
R-HSA-201681
R-HSA-201681
Reactome Name: TCF dependent signaling in response to WNT
See in Reactome
R-HSA-5683057
R-HSA-5683057
Reactome Name: MAPK family signaling cascades
See in Reactome
R-HSA-113510
R-HSA-113510
Reactome Name: E2F mediated regulation of DNA replication
See in Reactome
R-HSA-927802
R-HSA-69618
R-HSA-162582
R-HSA-68875
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Metabolism
Cell Cycle
Gene expression (Transcription)
Immune System
Metabolism of RNA
Hemostasis
Signal Transduction
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R-HSA-113503
(
R-HSA-113501
)
R-HSA-113503
Reaction Name: PP2A mediated localization of RB1 protein in chromatin
See in Reactome
R-HSA-1295599
(
R-HSA-1295596
)
R-HSA-1295599
Reaction Name: SPRY2 translocates to the plasma membrane
See in Reactome
R-HSA-1295609
(
R-HSA-1295596
)
R-HSA-1295609
Reaction Name: SRC phosphorylates SPRY2 on Y55 and Y227
See in Reactome
R-HSA-1295613
(
R-HSA-1295596
)
R-HSA-1295622
(
R-HSA-1295596
)
R-HSA-1295632
(
R-HSA-1295596
)
R-HSA-1363274
(
R-HSA-69231
)
R-HSA-1363274
Reaction Name: Dephosphorylation of p107 (RBL1) by PP2A
See in Reactome
R-HSA-1363276
(
R-HSA-69231
)
R-HSA-1363276
Reaction Name: Dephosphorylation of p130 (RBL2) by PP2A
See in Reactome
R-HSA-141409
(
R-HSA-141444
)
R-HSA-141422
(
R-HSA-141444
)
R-HSA-141422
Reaction Name: MAD2 converted to an inhibitory state via interaction with Mad1
See in Reactome
R-HSA-141431
(
R-HSA-141444
)
R-HSA-141431
Reaction Name: MAD2 associates with the Mad1 kinetochore complex
See in Reactome
R-HSA-141439
(
R-HSA-141444
)
R-HSA-141439
Reaction Name: Release of activated MAD2 from kinetochores
See in Reactome
R-HSA-1549564
(
R-HSA-1295596
)
R-HSA-163688
(
R-HSA-163685;
R-HSA-163767
)
R-HSA-163688
Reaction Name: Dephosphorylation of pChREBP (Thr 666) by PP2A
See in Reactome
R-HSA-163689
(
R-HSA-163685;
R-HSA-163767
)
R-HSA-163689
Reaction Name: Dephosphorylation of pChREBP (Ser 196) by PP2A
See in Reactome
R-HSA-163750
(
R-HSA-163685;
R-HSA-163767;
R-HSA-9634600
)
R-HSA-163750
Reaction Name: Dephosphorylation of phosphoPFKFB1 by PP2A complex
See in Reactome
R-HSA-163769
(
R-HSA-163685
)
R-HSA-163769
Reaction Name: Activation of PP2A by Xylulose-5-phosphate
See in Reactome
R-HSA-1638803
(
R-HSA-2500257;
R-HSA-68877
)
R-HSA-1638803
Reaction Name: Phosphorylation of cohesin by PLK1 at centromeres
See in Reactome
R-HSA-1638821
(
R-HSA-2500257;
R-HSA-68877
)
R-HSA-1638821
Reaction Name: PP2A-B56 dephosphorylates centromeric cohesin
See in Reactome
R-HSA-164056
(
R-HSA-163685;
R-HSA-163767
)
R-HSA-164056
Reaction Name: Dephosphorylation of pChREBP (Ser 568) by PP2A
See in Reactome
R-HSA-195251
(
R-HSA-195253
)
R-HSA-195251
Reaction Name: Assembly of the destruction complex
See in Reactome
R-HSA-195275
(
R-HSA-195253
)
R-HSA-195275
Reaction Name: Phosphorylation of APC component of the destruction complex
See in Reactome
R-HSA-195280
(
R-HSA-195253
)
R-HSA-195280
Reaction Name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex
See in Reactome
R-HSA-195283
(
R-HSA-195253;
R-HSA-196299
)
R-HSA-195283
Reaction Name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3
See in Reactome
R-HSA-195287
(
R-HSA-195253;
R-HSA-196299
)
R-HSA-195287
Reaction Name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3
See in Reactome
R-HSA-195300
(
R-HSA-195253;
R-HSA-196299
)
R-HSA-195300
Reaction Name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3
See in Reactome
R-HSA-195304
(
R-HSA-195253
)
R-HSA-195304
Reaction Name: Association of beta-catenin with the destruction complex
See in Reactome
R-HSA-195318
(
R-HSA-195253;
R-HSA-196299
)
R-HSA-195318
Reaction Name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha
See in Reactome
R-HSA-199959
(
R-HSA-198753;
R-HSA-202670
)
R-HSA-199959
Reaction Name: ERKs are inactivated by protein phosphatase 2A
See in Reactome
R-HSA-201685
(
R-HSA-4641262
)
R-HSA-201685
Reaction Name: Beta-catenin is released from the destruction complex
See in Reactome
R-HSA-201790
(
R-HSA-180024
)
R-HSA-201790
Reaction Name: DARPP-32 is dephosphorylated on Thr75 by PP2A
See in Reactome
R-HSA-2130279
(
R-HSA-195253
)
R-HSA-2130279
Reaction Name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex
See in Reactome
R-HSA-2130282
(
R-HSA-195253
)
R-HSA-2130282
Reaction Name: Degradation of ubiquitinated beta catenin by the proteasome
See in Reactome
R-HSA-2130286
(
R-HSA-195253
)
R-HSA-2130286
Reaction Name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1)
See in Reactome
R-HSA-2430552
(
R-HSA-2465910
)
R-HSA-2430552
Reaction Name: p-S62-ARPP19/p-S67-ENSA binds PP2A-PPP2R2D
See in Reactome
R-HSA-2467809
(
R-HSA-2467813
)
R-HSA-2467809
Reaction Name: ESPL1 (Separase) cleaves centromeric cohesin
See in Reactome
R-HSA-2467811
(
R-HSA-2467813
)
R-HSA-2467811
Reaction Name: Separation of sister chromatids
See in Reactome
R-HSA-2468287
(
R-HSA-2500257;
R-HSA-68877
)
R-HSA-2468287
Reaction Name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres
See in Reactome
R-HSA-2484822
(
R-HSA-2500257;
R-HSA-68877
)
R-HSA-2995388
(
R-HSA-2995383
)
R-HSA-3601585
(
R-HSA-4641262
)
R-HSA-3601585
Reaction Name: PP2A dephosphorylates AXIN, APC and CTNNB1 in the destruction complex
See in Reactome
R-HSA-375302
(
R-HSA-68877
)
R-HSA-375302
Reaction Name: Kinetochore capture of astral microtubules
See in Reactome
R-HSA-388809
(
R-HSA-389513
)
R-HSA-388833
(
R-HSA-389513
)
R-HSA-389532
(
R-HSA-389513
)
R-HSA-390329
(
R-HSA-389513
)
R-HSA-390329
Reaction Name: Dephosphorylation of AKT by PP2A
See in Reactome
R-HSA-4088141
(
R-HSA-69273
)
R-HSA-4088141
Reaction Name: PP2A-PPP2R2A dephosphorylates FOXM1
See in Reactome
R-HSA-432143
(
R-HSA-432142
)
R-HSA-5229343
(
R-HSA-195253
)
R-HSA-5229343
Reaction Name: AXIN is phosphorylated in the destruction complex
See in Reactome
R-HSA-5666129
(
R-HSA-5663220
)
R-HSA-5666129
Reaction Name: CDC42:GTP recruits DIAPH2-2 to kinetochores
See in Reactome
R-HSA-5666160
(
R-HSA-5663220
)
R-HSA-5666160
Reaction Name: AURKB phosphorylates DIAPH2-2 at kinetochores
See in Reactome
R-HSA-5666169
(
R-HSA-5663220
)
R-HSA-5666169
Reaction Name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2
See in Reactome
R-HSA-5672957
(
R-HSA-5673000
)
R-HSA-5672961
(
R-HSA-5673000
)
R-HSA-5672961
Reaction Name: PP2A dephosphorylates inactive RAFs
See in Reactome
R-HSA-5675431
(
R-HSA-5675221
)
R-HSA-6792863
(
R-HSA-6804757
)
R-HSA-6792863
Reaction Name: PP2A-PP2R5C dephosphorylates MDM2
See in Reactome
R-HSA-6792871
(
R-HSA-6804757
)
R-HSA-6792871
Reaction Name: CCNG1 recruits PP2A-PPP2R5C to MDM2
See in Reactome
R-HSA-6811454
(
R-HSA-6811558
)
R-HSA-6811472
(
R-HSA-6811558
)
R-HSA-6811472
Reaction Name: IER3 recruits MAPKs to PP2A-B56-beta,gamma
See in Reactome
R-HSA-6811504
(
R-HSA-6811558
)
R-HSA-6811504
Reaction Name: AKT1 dephosphorylation by PP2A-B56-beta,gamma
See in Reactome
R-HSA-8856945
(
R-HSA-69273
)
R-HSA-8856951
(
R-HSA-69273
)
R-HSA-8857925
(
R-HSA-6811558
)
R-HSA-8857925
Reaction Name: Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307
See in Reactome
R-HSA-927813
(
R-HSA-975957
)
R-HSA-927813
Reaction Name: p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A
See in Reactome
R-HSA-927830
(
R-HSA-975957
)
R-HSA-927830
Reaction Name: Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex
See in Reactome
R-HSA-927836
(
R-HSA-975957
)
R-HSA-927836
Reaction Name: SMG6 hydrolyzes mRNA with premature termination codon
See in Reactome
R-HSA-934559
(
R-HSA-1295596
)
R-HSA-934559
Reaction Name: SPRY2 is phosphorylated by phosphorylated MNK1
See in Reactome
R-HSA-9648114
(
R-HSA-68877;
R-HSA-9648025
)
R-HSA-9648114
Reaction Name: EML4 recruits NUDC to mitotic spindle
See in Reactome
R-HSA-9667965
(
R-HSA-2995383
)
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