DAR - Bologna Biocomputing Group

Search results (Reactome ID: R-HSA-2672351)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0005377	CLCN5	P51795	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2730692 ( R-HSA-2672351 ) R-HSA-2730692 Reaction Name: CLCN4/5/6 exchange Cl- for H+ See in Reactome
MONDO:0008055	CLCN1	P35523	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2744228 ( R-HSA-2672351 ) R-HSA-2744228 Reaction Name: CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region See in Reactome
MONDO:0008104	RAF1	P04049	2.7.11.1	R-HSA-5675221 R-HSA-5675221 Reactome Name: Negative regulation of MAPK pathway See in Reactome R-HSA-5674499 R-HSA-5674499 Reactome Name: Negative feedback regulation of MAPK pathway See in Reactome R-HSA-5674135 R-HSA-5674135 Reactome Name: MAP2K and MAPK activation See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-430116 R-HSA-430116 Reactome Name: GP1b-IX-V activation signalling See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome R-HSA-392517 R-HSA-392517 Reactome Name: Rap1 signalling See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome	Immune System Transport of small molecules Hemostasis Signal Transduction	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome R-HSA-392835 ( R-HSA-392517 ) R-HSA-392835 Reaction Name: Rap1 sequesters Raf1 to inhibit ERK cascade See in Reactome R-HSA-443439 ( R-HSA-430116 ) R-HSA-443439 Reaction Name: c-Src binds Raf1 See in Reactome R-HSA-443831 ( R-HSA-430116 ) R-HSA-443831 Reaction Name: 14-3-3-zeta binds Raf1 See in Reactome R-HSA-5624486 ( R-HSA-5621575 ) R-HSA-5624486 Reaction Name: SFKs phosphorylates RAF1 on Y340,Y341 See in Reactome R-HSA-5624492 ( R-HSA-5621575 ) R-HSA-5624492 Reaction Name: PAK phosphorylates p21 RAF1 on S338 See in Reactome R-HSA-5624494 ( R-HSA-5621575 ) R-HSA-5624494 Reaction Name: RAF1 binds p21 RAS:GTP See in Reactome R-HSA-5672950 ( R-HSA-5673000 ) R-HSA-5672950 Reaction Name: "Activator" RAF:YWHAB dimer binds RAS:GTP See in Reactome R-HSA-5672951 ( R-HSA-5673000 ) R-HSA-5672951 Reaction Name: Inactive RAFs bind YWHAB See in Reactome R-HSA-5672960 ( R-HSA-5673000 ) R-HSA-5672960 Reaction Name: YWHAB dimer dissociates from dephosphorylated RAF See in Reactome R-HSA-5672961 ( R-HSA-5673000 ) R-HSA-5672961 Reaction Name: PP2A dephosphorylates inactive RAFs See in Reactome R-HSA-5672966 ( R-HSA-5673000 ) R-HSA-5672966 Reaction Name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers See in Reactome R-HSA-5672969 ( R-HSA-5673000 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-5672972 ( R-HSA-5674135 ) R-HSA-5672972 Reaction Name: MAP2Ks and MAPKs bind to the activated RAF complex See in Reactome R-HSA-5672973 ( R-HSA-5674135 ) R-HSA-5672973 Reaction Name: MAP2Ks phosphorylate MAPKs See in Reactome R-HSA-5672978 ( R-HSA-5674135 ) R-HSA-5672978 Reaction Name: RAF phosphorylates MAP2K dimer See in Reactome R-HSA-5672980 ( R-HSA-5674135 ) R-HSA-5672980 Reaction Name: Dissociation of RAS:RAF complex See in Reactome R-HSA-5674130 ( R-HSA-5674135 ) R-HSA-5674130 Reaction Name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane See in Reactome R-HSA-5674132 ( R-HSA-5674135 ) R-HSA-5674132 Reaction Name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components See in Reactome R-HSA-5674140 ( R-HSA-5675221 ) R-HSA-5674140 Reaction Name: PAQR3 binds inactive RAFs See in Reactome R-HSA-5675194 ( R-HSA-5674499; R-HSA-5675221 ) R-HSA-5675194 Reaction Name: Activated MAPK phosphorylates RAF1 See in Reactome R-HSA-5675417 ( R-HSA-5675221 ) R-HSA-5675417 Reaction Name: PEBP1 binds activated RAF1 See in Reactome R-HSA-5675431 ( R-HSA-5675221 ) R-HSA-5675431 Reaction Name: PP2A dephosphorylates RAF1 See in Reactome R-HSA-5675433 ( R-HSA-5675221 ) R-HSA-5675433 Reaction Name: PP5 dephosphorylates RAF1 S338 See in Reactome R-HSA-9653108 ( R-HSA-5673000 ) R-HSA-9653108 Reaction Name: Raf dimer inhibitors bind RAF heterodimers See in Reactome R-HSA-9657599 ( R-HSA-5674135 ) R-HSA-9657599 Reaction Name: Dual mechanism MAP2K inhibitors bind MAP2Ks See in Reactome R-HSA-9657603 ( R-HSA-5674135 ) R-HSA-9657603 Reaction Name: Dual mechanism MAPK inhibitors bind MAPKs See in Reactome R-HSA-9657606 ( R-HSA-5674135 ) R-HSA-9657606 Reaction Name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks See in Reactome R-HSA-9657608 ( R-HSA-5674135 ) R-HSA-9657608 Reaction Name: Single mechanism MAPK inhibitors bind phosphorylated MAPK See in Reactome R-HSA-9658445 ( R-HSA-5673000 ) R-HSA-9658445 Reaction Name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs See in Reactome
MONDO:0008156	CLCN7	P51798	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2730959 ( R-HSA-2672351 ) R-HSA-2730959 Reaction Name: CLCN7:OSTM1 exchanges Cl- for H+ See in Reactome
MONDO:0009693	SGK1	O00141	2.7.11.1	R-HSA-6804757 R-HSA-6804757 Reactome Name: Regulation of TP53 Degradation See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-6806003 R-HSA-6806003 Reactome Name: Regulation of TP53 Expression and Degradation See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Transport of small molecules Signal Transduction	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome R-HSA-6795290 ( R-HSA-6804757 ) R-HSA-6795290 Reaction Name: TORC2 complex phosphorylates SGK1 See in Reactome R-HSA-6795460 ( R-HSA-6804757 ) R-HSA-6795460 Reaction Name: SGK1 phosphorylates MDM2 See in Reactome R-HSA-6795473 ( R-HSA-6804757 ) R-HSA-6795473 Reaction Name: PDPK1 phosphorylates SGK1 See in Reactome R-HSA-9022764 ( R-HSA-8986944 ) R-HSA-9022764 Reaction Name: SGK1 gene expression is inhibited by MECP2 See in Reactome R-HSA-9612501 ( R-HSA-9031628 ) R-HSA-9612501 Reaction Name: SGK phosphorylates CREB1 See in Reactome R-HSA-9612509 ( R-HSA-9031628 ) R-HSA-9612509 Reaction Name: SGK phosphorylates SRF See in Reactome
MONDO:0009715	CLCN1	P35523	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2744228 ( R-HSA-2672351 ) R-HSA-2744228 Reaction Name: CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region See in Reactome
MONDO:0009885	ANO6	Q4KMQ2	-	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Immune System Transport of small molecules	R-HSA-2684901 ( R-HSA-2672351 ) R-HSA-2684901 Reaction Name: ANOs transport cytosolic Cl- to extracellular region See in Reactome R-HSA-6798747 ( R-HSA-6798695 ) R-HSA-6798747 Reaction Name: Exocytosis of tertiary granule membrane proteins See in Reactome R-HSA-6799350 ( R-HSA-6798695 ) R-HSA-6799350 Reaction Name: Exocytosis of specific granule membrane proteins See in Reactome
MONDO:0010225	CLCN5	P51795	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2730692 ( R-HSA-2672351 ) R-HSA-2730692 Reaction Name: CLCN4/5/6 exchange Cl- for H+ See in Reactome
MONDO:0010358	CLCN5	P51795	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2730692 ( R-HSA-2672351 ) R-HSA-2730692 Reaction Name: CLCN4/5/6 exchange Cl- for H+ See in Reactome
MONDO:0010644	CLCN5	P51795	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2730692 ( R-HSA-2672351 ) R-HSA-2730692 Reaction Name: CLCN4/5/6 exchange Cl- for H+ See in Reactome
MONDO:0010687	CLCN5	P51795	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2730692 ( R-HSA-2672351 ) R-HSA-2730692 Reaction Name: CLCN4/5/6 exchange Cl- for H+ See in Reactome
MONDO:0011106	ASPH	Q12797	1.14.11.16	R-HSA-5578775 R-HSA-5578775 Reactome Name: Ion homeostasis See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-397014 R-HSA-397014 Reactome Name: Muscle contraction See in Reactome R-HSA-5576891 R-HSA-5576891 Reactome Name: Cardiac conduction See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Muscle contraction Transport of small molecules	R-HSA-2855020 ( R-HSA-2672351; R-HSA-5578775 ) R-HSA-2855020 Reaction Name: RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol See in Reactome
MONDO:0012676	CLCN7	P51798	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2730959 ( R-HSA-2672351 ) R-HSA-2730959 Reaction Name: CLCN7:OSTM1 exchanges Cl- for H+ See in Reactome
MONDO:0012679	CLCN7	P51798	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2730959 ( R-HSA-2672351 ) R-HSA-2730959 Reaction Name: CLCN7:OSTM1 exchanges Cl- for H+ See in Reactome
MONDO:0012690	RAF1	P04049	2.7.11.1	R-HSA-5675221 R-HSA-5675221 Reactome Name: Negative regulation of MAPK pathway See in Reactome R-HSA-5674499 R-HSA-5674499 Reactome Name: Negative feedback regulation of MAPK pathway See in Reactome R-HSA-5674135 R-HSA-5674135 Reactome Name: MAP2K and MAPK activation See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-430116 R-HSA-430116 Reactome Name: GP1b-IX-V activation signalling See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome R-HSA-392517 R-HSA-392517 Reactome Name: Rap1 signalling See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome	Immune System Transport of small molecules Hemostasis Signal Transduction	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome R-HSA-392835 ( R-HSA-392517 ) R-HSA-392835 Reaction Name: Rap1 sequesters Raf1 to inhibit ERK cascade See in Reactome R-HSA-443439 ( R-HSA-430116 ) R-HSA-443439 Reaction Name: c-Src binds Raf1 See in Reactome R-HSA-443831 ( R-HSA-430116 ) R-HSA-443831 Reaction Name: 14-3-3-zeta binds Raf1 See in Reactome R-HSA-5624486 ( R-HSA-5621575 ) R-HSA-5624486 Reaction Name: SFKs phosphorylates RAF1 on Y340,Y341 See in Reactome R-HSA-5624492 ( R-HSA-5621575 ) R-HSA-5624492 Reaction Name: PAK phosphorylates p21 RAF1 on S338 See in Reactome R-HSA-5624494 ( R-HSA-5621575 ) R-HSA-5624494 Reaction Name: RAF1 binds p21 RAS:GTP See in Reactome R-HSA-5672950 ( R-HSA-5673000 ) R-HSA-5672950 Reaction Name: "Activator" RAF:YWHAB dimer binds RAS:GTP See in Reactome R-HSA-5672951 ( R-HSA-5673000 ) R-HSA-5672951 Reaction Name: Inactive RAFs bind YWHAB See in Reactome R-HSA-5672960 ( R-HSA-5673000 ) R-HSA-5672960 Reaction Name: YWHAB dimer dissociates from dephosphorylated RAF See in Reactome R-HSA-5672961 ( R-HSA-5673000 ) R-HSA-5672961 Reaction Name: PP2A dephosphorylates inactive RAFs See in Reactome R-HSA-5672966 ( R-HSA-5673000 ) R-HSA-5672966 Reaction Name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers See in Reactome R-HSA-5672969 ( R-HSA-5673000 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-5672972 ( R-HSA-5674135 ) R-HSA-5672972 Reaction Name: MAP2Ks and MAPKs bind to the activated RAF complex See in Reactome R-HSA-5672973 ( R-HSA-5674135 ) R-HSA-5672973 Reaction Name: MAP2Ks phosphorylate MAPKs See in Reactome R-HSA-5672978 ( R-HSA-5674135 ) R-HSA-5672978 Reaction Name: RAF phosphorylates MAP2K dimer See in Reactome R-HSA-5672980 ( R-HSA-5674135 ) R-HSA-5672980 Reaction Name: Dissociation of RAS:RAF complex See in Reactome R-HSA-5674130 ( R-HSA-5674135 ) R-HSA-5674130 Reaction Name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane See in Reactome R-HSA-5674132 ( R-HSA-5674135 ) R-HSA-5674132 Reaction Name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components See in Reactome R-HSA-5674140 ( R-HSA-5675221 ) R-HSA-5674140 Reaction Name: PAQR3 binds inactive RAFs See in Reactome R-HSA-5675194 ( R-HSA-5674499; R-HSA-5675221 ) R-HSA-5675194 Reaction Name: Activated MAPK phosphorylates RAF1 See in Reactome R-HSA-5675417 ( R-HSA-5675221 ) R-HSA-5675417 Reaction Name: PEBP1 binds activated RAF1 See in Reactome R-HSA-5675431 ( R-HSA-5675221 ) R-HSA-5675431 Reaction Name: PP2A dephosphorylates RAF1 See in Reactome R-HSA-5675433 ( R-HSA-5675221 ) R-HSA-5675433 Reaction Name: PP5 dephosphorylates RAF1 S338 See in Reactome R-HSA-9653108 ( R-HSA-5673000 ) R-HSA-9653108 Reaction Name: Raf dimer inhibitors bind RAF heterodimers See in Reactome R-HSA-9657599 ( R-HSA-5674135 ) R-HSA-9657599 Reaction Name: Dual mechanism MAP2K inhibitors bind MAP2Ks See in Reactome R-HSA-9657603 ( R-HSA-5674135 ) R-HSA-9657603 Reaction Name: Dual mechanism MAPK inhibitors bind MAPKs See in Reactome R-HSA-9657606 ( R-HSA-5674135 ) R-HSA-9657606 Reaction Name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks See in Reactome R-HSA-9657608 ( R-HSA-5674135 ) R-HSA-9657608 Reaction Name: Single mechanism MAPK inhibitors bind phosphorylated MAPK See in Reactome R-HSA-9658445 ( R-HSA-5673000 ) R-HSA-9658445 Reaction Name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs See in Reactome
MONDO:0012691	RAF1	P04049	2.7.11.1	R-HSA-5675221 R-HSA-5675221 Reactome Name: Negative regulation of MAPK pathway See in Reactome R-HSA-5674499 R-HSA-5674499 Reactome Name: Negative feedback regulation of MAPK pathway See in Reactome R-HSA-5674135 R-HSA-5674135 Reactome Name: MAP2K and MAPK activation See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-430116 R-HSA-430116 Reactome Name: GP1b-IX-V activation signalling See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome R-HSA-392517 R-HSA-392517 Reactome Name: Rap1 signalling See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome	Immune System Transport of small molecules Hemostasis Signal Transduction	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome R-HSA-392835 ( R-HSA-392517 ) R-HSA-392835 Reaction Name: Rap1 sequesters Raf1 to inhibit ERK cascade See in Reactome R-HSA-443439 ( R-HSA-430116 ) R-HSA-443439 Reaction Name: c-Src binds Raf1 See in Reactome R-HSA-443831 ( R-HSA-430116 ) R-HSA-443831 Reaction Name: 14-3-3-zeta binds Raf1 See in Reactome R-HSA-5624486 ( R-HSA-5621575 ) R-HSA-5624486 Reaction Name: SFKs phosphorylates RAF1 on Y340,Y341 See in Reactome R-HSA-5624492 ( R-HSA-5621575 ) R-HSA-5624492 Reaction Name: PAK phosphorylates p21 RAF1 on S338 See in Reactome R-HSA-5624494 ( R-HSA-5621575 ) R-HSA-5624494 Reaction Name: RAF1 binds p21 RAS:GTP See in Reactome R-HSA-5672950 ( R-HSA-5673000 ) R-HSA-5672950 Reaction Name: "Activator" RAF:YWHAB dimer binds RAS:GTP See in Reactome R-HSA-5672951 ( R-HSA-5673000 ) R-HSA-5672951 Reaction Name: Inactive RAFs bind YWHAB See in Reactome R-HSA-5672960 ( R-HSA-5673000 ) R-HSA-5672960 Reaction Name: YWHAB dimer dissociates from dephosphorylated RAF See in Reactome R-HSA-5672961 ( R-HSA-5673000 ) R-HSA-5672961 Reaction Name: PP2A dephosphorylates inactive RAFs See in Reactome R-HSA-5672966 ( R-HSA-5673000 ) R-HSA-5672966 Reaction Name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers See in Reactome R-HSA-5672969 ( R-HSA-5673000 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-5672972 ( R-HSA-5674135 ) R-HSA-5672972 Reaction Name: MAP2Ks and MAPKs bind to the activated RAF complex See in Reactome R-HSA-5672973 ( R-HSA-5674135 ) R-HSA-5672973 Reaction Name: MAP2Ks phosphorylate MAPKs See in Reactome R-HSA-5672978 ( R-HSA-5674135 ) R-HSA-5672978 Reaction Name: RAF phosphorylates MAP2K dimer See in Reactome R-HSA-5672980 ( R-HSA-5674135 ) R-HSA-5672980 Reaction Name: Dissociation of RAS:RAF complex See in Reactome R-HSA-5674130 ( R-HSA-5674135 ) R-HSA-5674130 Reaction Name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane See in Reactome R-HSA-5674132 ( R-HSA-5674135 ) R-HSA-5674132 Reaction Name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components See in Reactome R-HSA-5674140 ( R-HSA-5675221 ) R-HSA-5674140 Reaction Name: PAQR3 binds inactive RAFs See in Reactome R-HSA-5675194 ( R-HSA-5674499; R-HSA-5675221 ) R-HSA-5675194 Reaction Name: Activated MAPK phosphorylates RAF1 See in Reactome R-HSA-5675417 ( R-HSA-5675221 ) R-HSA-5675417 Reaction Name: PEBP1 binds activated RAF1 See in Reactome R-HSA-5675431 ( R-HSA-5675221 ) R-HSA-5675431 Reaction Name: PP2A dephosphorylates RAF1 See in Reactome R-HSA-5675433 ( R-HSA-5675221 ) R-HSA-5675433 Reaction Name: PP5 dephosphorylates RAF1 S338 See in Reactome R-HSA-9653108 ( R-HSA-5673000 ) R-HSA-9653108 Reaction Name: Raf dimer inhibitors bind RAF heterodimers See in Reactome R-HSA-9657599 ( R-HSA-5674135 ) R-HSA-9657599 Reaction Name: Dual mechanism MAP2K inhibitors bind MAP2Ks See in Reactome R-HSA-9657603 ( R-HSA-5674135 ) R-HSA-9657603 Reaction Name: Dual mechanism MAPK inhibitors bind MAPKs See in Reactome R-HSA-9657606 ( R-HSA-5674135 ) R-HSA-9657606 Reaction Name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks See in Reactome R-HSA-9657608 ( R-HSA-5674135 ) R-HSA-9657608 Reaction Name: Single mechanism MAPK inhibitors bind phosphorylated MAPK See in Reactome R-HSA-9658445 ( R-HSA-5673000 ) R-HSA-9658445 Reaction Name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs See in Reactome
MONDO:0013777	WNK4	Q96J92	2.7.11.1	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome
MONDO:0013778	WNK1	Q9H4A3	2.7.11.1	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome
MONDO:0014019	ANO3	Q9BYT9	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2684901 ( R-HSA-2672351 ) R-HSA-2684901 Reaction Name: ANOs transport cytosolic Cl- to extracellular region See in Reactome
MONDO:0014396	RAF1	P04049	2.7.11.1	R-HSA-5675221 R-HSA-5675221 Reactome Name: Negative regulation of MAPK pathway See in Reactome R-HSA-5674499 R-HSA-5674499 Reactome Name: Negative feedback regulation of MAPK pathway See in Reactome R-HSA-5674135 R-HSA-5674135 Reactome Name: MAP2K and MAPK activation See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-430116 R-HSA-430116 Reactome Name: GP1b-IX-V activation signalling See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome R-HSA-392517 R-HSA-392517 Reactome Name: Rap1 signalling See in Reactome R-HSA-5673000 R-HSA-5673000 Reactome Name: RAF activation See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome	Immune System Transport of small molecules Hemostasis Signal Transduction	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome R-HSA-392835 ( R-HSA-392517 ) R-HSA-392835 Reaction Name: Rap1 sequesters Raf1 to inhibit ERK cascade See in Reactome R-HSA-443439 ( R-HSA-430116 ) R-HSA-443439 Reaction Name: c-Src binds Raf1 See in Reactome R-HSA-443831 ( R-HSA-430116 ) R-HSA-443831 Reaction Name: 14-3-3-zeta binds Raf1 See in Reactome R-HSA-5624486 ( R-HSA-5621575 ) R-HSA-5624486 Reaction Name: SFKs phosphorylates RAF1 on Y340,Y341 See in Reactome R-HSA-5624492 ( R-HSA-5621575 ) R-HSA-5624492 Reaction Name: PAK phosphorylates p21 RAF1 on S338 See in Reactome R-HSA-5624494 ( R-HSA-5621575 ) R-HSA-5624494 Reaction Name: RAF1 binds p21 RAS:GTP See in Reactome R-HSA-5672950 ( R-HSA-5673000 ) R-HSA-5672950 Reaction Name: "Activator" RAF:YWHAB dimer binds RAS:GTP See in Reactome R-HSA-5672951 ( R-HSA-5673000 ) R-HSA-5672951 Reaction Name: Inactive RAFs bind YWHAB See in Reactome R-HSA-5672960 ( R-HSA-5673000 ) R-HSA-5672960 Reaction Name: YWHAB dimer dissociates from dephosphorylated RAF See in Reactome R-HSA-5672961 ( R-HSA-5673000 ) R-HSA-5672961 Reaction Name: PP2A dephosphorylates inactive RAFs See in Reactome R-HSA-5672966 ( R-HSA-5673000 ) R-HSA-5672966 Reaction Name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers See in Reactome R-HSA-5672969 ( R-HSA-5673000 ) R-HSA-5672969 Reaction Name: Phosphorylation of RAF See in Reactome R-HSA-5672972 ( R-HSA-5674135 ) R-HSA-5672972 Reaction Name: MAP2Ks and MAPKs bind to the activated RAF complex See in Reactome R-HSA-5672973 ( R-HSA-5674135 ) R-HSA-5672973 Reaction Name: MAP2Ks phosphorylate MAPKs See in Reactome R-HSA-5672978 ( R-HSA-5674135 ) R-HSA-5672978 Reaction Name: RAF phosphorylates MAP2K dimer See in Reactome R-HSA-5672980 ( R-HSA-5674135 ) R-HSA-5672980 Reaction Name: Dissociation of RAS:RAF complex See in Reactome R-HSA-5674130 ( R-HSA-5674135 ) R-HSA-5674130 Reaction Name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane See in Reactome R-HSA-5674132 ( R-HSA-5674135 ) R-HSA-5674132 Reaction Name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components See in Reactome R-HSA-5674140 ( R-HSA-5675221 ) R-HSA-5674140 Reaction Name: PAQR3 binds inactive RAFs See in Reactome R-HSA-5675194 ( R-HSA-5674499; R-HSA-5675221 ) R-HSA-5675194 Reaction Name: Activated MAPK phosphorylates RAF1 See in Reactome R-HSA-5675417 ( R-HSA-5675221 ) R-HSA-5675417 Reaction Name: PEBP1 binds activated RAF1 See in Reactome R-HSA-5675431 ( R-HSA-5675221 ) R-HSA-5675431 Reaction Name: PP2A dephosphorylates RAF1 See in Reactome R-HSA-5675433 ( R-HSA-5675221 ) R-HSA-5675433 Reaction Name: PP5 dephosphorylates RAF1 S338 See in Reactome R-HSA-9653108 ( R-HSA-5673000 ) R-HSA-9653108 Reaction Name: Raf dimer inhibitors bind RAF heterodimers See in Reactome R-HSA-9657599 ( R-HSA-5674135 ) R-HSA-9657599 Reaction Name: Dual mechanism MAP2K inhibitors bind MAP2Ks See in Reactome R-HSA-9657603 ( R-HSA-5674135 ) R-HSA-9657603 Reaction Name: Dual mechanism MAPK inhibitors bind MAPKs See in Reactome R-HSA-9657606 ( R-HSA-5674135 ) R-HSA-9657606 Reaction Name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks See in Reactome R-HSA-9657608 ( R-HSA-5674135 ) R-HSA-9657608 Reaction Name: Single mechanism MAPK inhibitors bind phosphorylated MAPK See in Reactome R-HSA-9658445 ( R-HSA-5673000 ) R-HSA-9658445 Reaction Name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs See in Reactome
MONDO:0014966	NEDD4L	Q96PU5	2.3.2.26	R-HSA-983168 R-HSA-983168 Reactome Name: Antigen processing: Ubiquitination & Proteasome degradation See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome R-HSA-2173795 R-HSA-2173795 Reactome Name: Downregulation of SMAD2/3:SMAD4 transcriptional activity See in Reactome R-HSA-2173788 R-HSA-2173788 Reactome Name: Downregulation of TGF-beta receptor signaling See in Reactome	R-HSA-2173789 R-HSA-2173789 Reactome Name: TGF-beta receptor signaling activates SMADs See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-170834 R-HSA-170834 Reactome Name: Signaling by TGF-beta Receptor Complex See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-983169 R-HSA-983169 Reactome Name: Class I MHC mediated antigen processing & presentation See in Reactome R-HSA-9006936 R-HSA-9006936 Reactome Name: Signaling by TGFB family members See in Reactome R-HSA-2173793 R-HSA-2173793 Reactome Name: Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Immune System Transport of small molecules Signal Transduction	R-HSA-178218 ( R-HSA-2173788 ) R-HSA-178218 Reaction Name: SMAD7:SMURF complex binds to phosphorylated TGFBR1 See in Reactome R-HSA-2169050 ( R-HSA-2173788 ) R-HSA-2169050 Reaction Name: SMURFs/NEDD4L ubiquitinate phosphorylated TGFBR1 and SMAD7 See in Reactome R-HSA-2176416 ( R-HSA-2173788 ) R-HSA-2176416 Reaction Name: NEDD4L ubiquitin ligase binds SMAD7 See in Reactome R-HSA-2176417 ( R-HSA-2173788 ) R-HSA-2176417 Reaction Name: SMAD7:NEDD4L complex translocates to the cytosol See in Reactome R-HSA-2176491 ( R-HSA-2173795 ) R-HSA-2176491 Reaction Name: NEDD4L binds phosphorylated linker region of SMAD2/3 See in Reactome R-HSA-2176502 ( R-HSA-2173795 ) R-HSA-2176502 Reaction Name: NEDD4L ubiquitinates SMAD2/3 See in Reactome R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome R-HSA-983140 ( R-HSA-983168 ) R-HSA-983140 Reaction Name: Transfer of Ub from E2 to substrate and release of E2 See in Reactome R-HSA-983147 ( R-HSA-983168 ) R-HSA-983147 Reaction Name: Release of E3 from polyubiquitinated substrate See in Reactome R-HSA-983156 ( R-HSA-983168 ) R-HSA-983156 Reaction Name: Polyubiquitination of substrate See in Reactome R-HSA-983157 ( R-HSA-983168 ) R-HSA-983157 Reaction Name: Interaction of E3 with substrate and E2-Ub complex See in Reactome
MONDO:0019438	SGK1	O00141	2.7.11.1	R-HSA-6804757 R-HSA-6804757 Reactome Name: Regulation of TP53 Degradation See in Reactome R-HSA-8986944 R-HSA-8986944 Reactome Name: Transcriptional Regulation by MECP2 See in Reactome R-HSA-9031628 R-HSA-9031628 Reactome Name: NGF-stimulated transcription See in Reactome R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-6806003 R-HSA-6806003 Reactome Name: Regulation of TP53 Expression and Degradation See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-198725 R-HSA-198725 Reactome Name: Nuclear Events (kinase and transcription factor activation) See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Transport of small molecules Signal Transduction	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome R-HSA-6795290 ( R-HSA-6804757 ) R-HSA-6795290 Reaction Name: TORC2 complex phosphorylates SGK1 See in Reactome R-HSA-6795460 ( R-HSA-6804757 ) R-HSA-6795460 Reaction Name: SGK1 phosphorylates MDM2 See in Reactome R-HSA-6795473 ( R-HSA-6804757 ) R-HSA-6795473 Reaction Name: PDPK1 phosphorylates SGK1 See in Reactome R-HSA-9022764 ( R-HSA-8986944 ) R-HSA-9022764 Reaction Name: SGK1 gene expression is inhibited by MECP2 See in Reactome R-HSA-9612501 ( R-HSA-9031628 ) R-HSA-9612501 Reaction Name: SGK phosphorylates CREB1 See in Reactome R-HSA-9612509 ( R-HSA-9031628 ) R-HSA-9612509 Reaction Name: SGK phosphorylates SRF See in Reactome
MONDO:0024309	WNK1	Q9H4A3	2.7.11.1	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2682349 ( R-HSA-2672351 ) R-HSA-2682349 Reaction Name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels See in Reactome
MONDO:0030947	CLCN6	P51797	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2730692 ( R-HSA-2672351 ) R-HSA-2730692 Reaction Name: CLCN4/5/6 exchange Cl- for H+ See in Reactome
MONDO:0032805	CLCN7	P51798	-	R-HSA-2672351 R-HSA-2672351 Reactome Name: Stimuli-sensing channels See in Reactome	R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-2730959 ( R-HSA-2672351 ) R-HSA-2730959 Reaction Name: CLCN7:OSTM1 exchanges Cl- for H+ See in Reactome

Number of enzymes:	12
Number of disease:	25
Number of reactomes:	16
Number of reactions:	53

Search summary (Reactome ID: R-HSA-2672351)

Search results (Reactome ID: R-HSA-2672351)

MONDO:0005377

R-HSA-2672351

R-HSA-983712

R-HSA-382551

R-HSA-2730692

MONDO:0008055

R-HSA-2672351

R-HSA-983712

R-HSA-382551

R-HSA-2744228

MONDO:0008104

R-HSA-5675221

R-HSA-5674499

R-HSA-5674135

R-HSA-5621575

R-HSA-430116

R-HSA-2672351

R-HSA-392517

R-HSA-5673000

R-HSA-5621481

R-HSA-5683057

R-HSA-168256

R-HSA-983712

R-HSA-168249

R-HSA-382551

R-HSA-1280218

R-HSA-5673001

R-HSA-5684996

R-HSA-109582

R-HSA-162582

R-HSA-76002

R-HSA-2682349

R-HSA-392835

R-HSA-443439

R-HSA-443831

R-HSA-5624486

R-HSA-5624492

R-HSA-5624494

R-HSA-5672950

R-HSA-5672951

R-HSA-5672960

R-HSA-5672961

R-HSA-5672966

R-HSA-5672969

R-HSA-5672972

R-HSA-5672973

R-HSA-5672978

R-HSA-5672980

R-HSA-5674130

R-HSA-5674132

R-HSA-5674140

R-HSA-5675194

R-HSA-5675417

R-HSA-5675431

R-HSA-5675433

R-HSA-9653108

R-HSA-9657599

R-HSA-9657603

R-HSA-9657606

R-HSA-9657608

R-HSA-9658445

MONDO:0008156

R-HSA-2672351

R-HSA-983712

R-HSA-382551

R-HSA-2730959

MONDO:0009693

R-HSA-6804757

R-HSA-8986944

R-HSA-9031628

R-HSA-2672351

R-HSA-3700989

R-HSA-5633007

R-HSA-166520

R-HSA-6806003

R-HSA-74160

R-HSA-983712

R-HSA-382551