DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-2514859)

Number of enzymes:	6
Number of disease:	11
Number of reactomes:	4
Number of reactions:	9

Search results (Reactome ID: R-HSA-2514859)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0000455	GUCY2D	Q02846	4.6.1.2	R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome	Sensory Perception	R-HSA-74885 ( R-HSA-2514859 ) R-HSA-74885 Reaction Name: GUCYs converts GTP to cGMP See in Reactome
MONDO:0008099	PDE6B	P35913	3.1.4.35	R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome R-HSA-2485179 R-HSA-2485179 Reactome Name: Activation of the phototransduction cascade See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Sensory Perception Signal Transduction	R-HSA-2584246 ( R-HSA-2514859 ) R-HSA-2584246 Reaction Name: GNAT1-GTP hydrolyses its bound GTP to GDP See in Reactome R-HSA-4086392 ( R-HSA-4086398 ) R-HSA-4086392 Reaction Name: PDE6 hydrolyses cGMP to GMP See in Reactome R-HSA-4086393 ( R-HSA-4086398 ) R-HSA-4086393 Reaction Name: G alpha t2 binds and activates PDE6 See in Reactome R-HSA-74059 ( R-HSA-2485179 ) R-HSA-74059 Reaction Name: PDE6 hydrolyses cGMP to GMP See in Reactome R-HSA-74065 ( R-HSA-2485179 ) R-HSA-74065 Reaction Name: GNAT1-GTP binds PDE6 and activates it See in Reactome
MONDO:0008764	GUCY2D	Q02846	4.6.1.2	R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome	Sensory Perception	R-HSA-74885 ( R-HSA-2514859 ) R-HSA-74885 Reaction Name: GUCYs converts GTP to cGMP See in Reactome
MONDO:0011143	GUCY2D	Q02846	4.6.1.2	R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome	Sensory Perception	R-HSA-74885 ( R-HSA-2514859 ) R-HSA-74885 Reaction Name: GUCYs converts GTP to cGMP See in Reactome
MONDO:0011669	CAMKMT	Q7Z624	2.1.1.60	R-HSA-8876725 R-HSA-8876725 Reactome Name: Protein methylation See in Reactome R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Sensory Perception Metabolism of proteins	R-HSA-6786205 ( R-HSA-2514859; R-HSA-8876725 ) R-HSA-6786205 Reaction Name: KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 See in Reactome
MONDO:0013259	GRK1	Q15835	2.7.11.14	R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome	Sensory Perception	R-HSA-2581474 ( R-HSA-2514859 ) R-HSA-2581474 Reaction Name: GRK1,4,7 phosphorylate MII to p-MII See in Reactome R-HSA-3229213 ( R-HSA-2514859 ) R-HSA-3229213 Reaction Name: RCVRN:Ca2+ binds to and inhibits GRK1 See in Reactome
MONDO:0013315	PDE6G	P18545	3.1.4.35	R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome R-HSA-2485179 R-HSA-2485179 Reactome Name: Activation of the phototransduction cascade See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Sensory Perception Signal Transduction	R-HSA-2584246 ( R-HSA-2514859 ) R-HSA-2584246 Reaction Name: GNAT1-GTP hydrolyses its bound GTP to GDP See in Reactome R-HSA-4086392 ( R-HSA-4086398 ) R-HSA-4086392 Reaction Name: PDE6 hydrolyses cGMP to GMP See in Reactome R-HSA-4086393 ( R-HSA-4086398 ) R-HSA-4086393 Reaction Name: G alpha t2 binds and activates PDE6 See in Reactome R-HSA-74059 ( R-HSA-2485179 ) R-HSA-74059 Reaction Name: PDE6 hydrolyses cGMP to GMP See in Reactome R-HSA-74065 ( R-HSA-2485179 ) R-HSA-74065 Reaction Name: GNAT1-GTP binds PDE6 and activates it See in Reactome
MONDO:0013429	PDE6B	P35913	3.1.4.35	R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome R-HSA-2485179 R-HSA-2485179 Reactome Name: Activation of the phototransduction cascade See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Sensory Perception Signal Transduction	R-HSA-2584246 ( R-HSA-2514859 ) R-HSA-2584246 Reaction Name: GNAT1-GTP hydrolyses its bound GTP to GDP See in Reactome R-HSA-4086392 ( R-HSA-4086398 ) R-HSA-4086392 Reaction Name: PDE6 hydrolyses cGMP to GMP See in Reactome R-HSA-4086393 ( R-HSA-4086398 ) R-HSA-4086393 Reaction Name: G alpha t2 binds and activates PDE6 See in Reactome R-HSA-74059 ( R-HSA-2485179 ) R-HSA-74059 Reaction Name: PDE6 hydrolyses cGMP to GMP See in Reactome R-HSA-74065 ( R-HSA-2485179 ) R-HSA-74065 Reaction Name: GNAT1-GTP binds PDE6 and activates it See in Reactome
MONDO:0013437	PDE6A	P16499	3.1.4.35	R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome R-HSA-2485179 R-HSA-2485179 Reactome Name: Activation of the phototransduction cascade See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Sensory Perception Signal Transduction	R-HSA-2584246 ( R-HSA-2514859 ) R-HSA-2584246 Reaction Name: GNAT1-GTP hydrolyses its bound GTP to GDP See in Reactome R-HSA-4086392 ( R-HSA-4086398 ) R-HSA-4086392 Reaction Name: PDE6 hydrolyses cGMP to GMP See in Reactome R-HSA-4086393 ( R-HSA-4086398 ) R-HSA-4086393 Reaction Name: G alpha t2 binds and activates PDE6 See in Reactome R-HSA-74059 ( R-HSA-2485179 ) R-HSA-74059 Reaction Name: PDE6 hydrolyses cGMP to GMP See in Reactome R-HSA-74065 ( R-HSA-2485179 ) R-HSA-74065 Reaction Name: GNAT1-GTP binds PDE6 and activates it See in Reactome
MONDO:0024539	GUCY2D	Q02846	4.6.1.2	R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome	Sensory Perception	R-HSA-74885 ( R-HSA-2514859 ) R-HSA-74885 Reaction Name: GUCYs converts GTP to cGMP See in Reactome
MONDO:0032811	GUCY2D	Q02846	4.6.1.2	R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome	Sensory Perception	R-HSA-74885 ( R-HSA-2514859 ) R-HSA-74885 Reaction Name: GUCYs converts GTP to cGMP See in Reactome