DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-2408550)

Number of enzymes:	2
Number of disease:	3
Number of reactomes:	5
Number of reactions:	8

Search results (Reactome ID: R-HSA-2408550)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0018662	PAPSS2	O95340	2.7.1.25 2.7.7.4	R-HSA-174362 R-HSA-174362 Reactome Name: Transport and synthesis of PAPS See in Reactome R-HSA-2408550 R-HSA-2408550 Reactome Name: Metabolism of ingested H2SeO4 and H2SeO3 into H2Se See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-156584 R-HSA-156584 Reactome Name: Cytosolic sulfonation of small molecules See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-2408522 R-HSA-2408522 Reactome Name: Selenoamino acid metabolism See in Reactome	Metabolism	R-HSA-174389 ( R-HSA-174362 ) R-HSA-174389 Reaction Name: PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS See in Reactome R-HSA-174392 ( R-HSA-174362 ) R-HSA-174392 Reaction Name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS See in Reactome R-HSA-2408525 ( R-HSA-2408550 ) R-HSA-2408525 Reaction Name: H2SeO4 is converted to APSe by PAPSS1,2 See in Reactome R-HSA-2408540 ( R-HSA-2408550 ) R-HSA-2408540 Reaction Name: APSe is phosphorylated to PAPSe by PAPSS1,2 See in Reactome
MONDO:0019531	GSR	P00390	1.8.1.7	R-HSA-499943 R-HSA-499943 Reactome Name: Interconversion of nucleotide di- and triphosphates See in Reactome R-HSA-3299685 R-HSA-3299685 Reactome Name: Detoxification of Reactive Oxygen Species See in Reactome R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome R-HSA-2408550 R-HSA-2408550 Reactome Name: Metabolism of ingested H2SeO4 and H2SeO3 into H2Se See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9711123 R-HSA-9711123 Reactome Name: Cellular response to chemical stress See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-2408522 R-HSA-2408522 Reactome Name: Selenoamino acid metabolism See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Cellular responses to stimuli Metabolism Gene expression (Transcription)	R-HSA-2408542 ( R-HSA-2408550 ) R-HSA-2408542 Reaction Name: GSSeSG is reduced to GSSeH and GSH by GSR See in Reactome R-HSA-3323079 ( R-HSA-3299685 ) R-HSA-3323079 Reaction Name: GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ See in Reactome R-HSA-71682 ( R-HSA-3299685; R-HSA-499943; R-HSA-5628897 ) R-HSA-71682 Reaction Name: glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ See in Reactome R-HSA-9761843 () R-HSA-9761843 Reaction Name: NFE2L2-dependent GSR gene expression See in Reactome
MONDO:0019666	PAPSS2	O95340	2.7.1.25 2.7.7.4	R-HSA-174362 R-HSA-174362 Reactome Name: Transport and synthesis of PAPS See in Reactome R-HSA-2408550 R-HSA-2408550 Reactome Name: Metabolism of ingested H2SeO4 and H2SeO3 into H2Se See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-156584 R-HSA-156584 Reactome Name: Cytosolic sulfonation of small molecules See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-2408522 R-HSA-2408522 Reactome Name: Selenoamino acid metabolism See in Reactome	Metabolism	R-HSA-174389 ( R-HSA-174362 ) R-HSA-174389 Reaction Name: PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS See in Reactome R-HSA-174392 ( R-HSA-174362 ) R-HSA-174392 Reaction Name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS See in Reactome R-HSA-2408525 ( R-HSA-2408550 ) R-HSA-2408525 Reaction Name: H2SeO4 is converted to APSe by PAPSS1,2 See in Reactome R-HSA-2408540 ( R-HSA-2408550 ) R-HSA-2408540 Reaction Name: APSe is phosphorylated to PAPSe by PAPSS1,2 See in Reactome