DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-2162123)

Number of enzymes:	3
Number of disease:	6
Number of reactomes:	10
Number of reactions:	10

Search results (Reactome ID: R-HSA-2162123)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007343	HPGD	P15428	1.1.1.- 1.1.1.232 1.1.1.141	R-HSA-9018676 R-HSA-9018676 Reactome Name: Biosynthesis of D-series resolvins See in Reactome R-HSA-9018896 R-HSA-9018896 Reactome Name: Biosynthesis of E-series 18(S)-resolvins See in Reactome R-HSA-2162123 R-HSA-2162123 Reactome Name: Synthesis of Prostaglandins (PG) and Thromboxanes (TX) See in Reactome R-HSA-2142700 R-HSA-2142700 Reactome Name: Synthesis of Lipoxins (LX) See in Reactome	R-HSA-9018677 R-HSA-9018677 Reactome Name: Biosynthesis of DHA-derived SPMs See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9018678 R-HSA-9018678 Reactome Name: Biosynthesis of specialized proresolving mediators (SPMs) See in Reactome R-HSA-9018679 R-HSA-9018679 Reactome Name: Biosynthesis of EPA-derived SPMs See in Reactome	Metabolism	R-HSA-2161662 ( R-HSA-2162123 ) R-HSA-2161662 Reaction Name: PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD See in Reactome R-HSA-2161779 ( R-HSA-2142700 ) R-HSA-2161779 Reaction Name: LXA4 is oxidised to 15k-LXA4 by HPGD See in Reactome R-HSA-9023968 ( R-HSA-9018896 ) R-HSA-9023968 Reaction Name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 See in Reactome R-HSA-9024766 ( R-HSA-9018676 ) R-HSA-9024766 Reaction Name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 See in Reactome
MONDO:0007781	PTGIS	Q16647	4.2.1.152 5.3.99.4	R-HSA-197264 R-HSA-197264 Reactome Name: Nicotinamide salvaging See in Reactome R-HSA-193807 R-HSA-193807 Reactome Name: Synthesis of bile acids and bile salts via 27-hydroxycholesterol See in Reactome R-HSA-211994 R-HSA-211994 Reactome Name: Sterols are 12-hydroxylated by CYP8B1 See in Reactome R-HSA-193368 R-HSA-193368 Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol See in Reactome R-HSA-193775 R-HSA-193775 Reactome Name: Synthesis of bile acids and bile salts via 24-hydroxycholesterol See in Reactome R-HSA-2162123 R-HSA-2162123 Reactome Name: Synthesis of Prostaglandins (PG) and Thromboxanes (TX) See in Reactome R-HSA-211979 R-HSA-211979 Reactome Name: Eicosanoids See in Reactome	R-HSA-196807 R-HSA-196807 Reactome Name: Nicotinate metabolism See in Reactome R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-194068 R-HSA-194068 Reactome Name: Bile acid and bile salt metabolism See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-192105 R-HSA-192105 Reactome Name: Synthesis of bile acids and bile salts See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-192157 ( R-HSA-193368; R-HSA-211994 ) R-HSA-192157 Reaction Name: CYP8B1 12-hydroxylates 4CHOL7aOLONE See in Reactome R-HSA-193709 ( R-HSA-193775; R-HSA-211994 ) R-HSA-193709 Reaction Name: CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL See in Reactome R-HSA-193845 ( R-HSA-193807; R-HSA-211994 ) R-HSA-193845 Reaction Name: CYP8B1 12-hydroxylates 4CHOL7a,27DONE See in Reactome R-HSA-76496 ( R-HSA-197264; R-HSA-211979; R-HSA-2162123 ) R-HSA-76496 Reaction Name: PTGIS, CYP8A1 isomerise PGH2 to PGI2 See in Reactome
MONDO:0009274	TBXAS1	P24557	4.2.1.152 5.3.99.5	R-HSA-211979 R-HSA-211979 Reactome Name: Eicosanoids See in Reactome R-HSA-2162123 R-HSA-2162123 Reactome Name: Synthesis of Prostaglandins (PG) and Thromboxanes (TX) See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-2161613 ( R-HSA-2162123 ) R-HSA-2161613 Reaction Name: PGH2 is degraded to 12S-HHT and MDA by TBXAS1 See in Reactome R-HSA-76500 ( R-HSA-211979; R-HSA-2162123 ) R-HSA-76500 Reaction Name: TBXAS1 isomerises PGH2 to TXA2 See in Reactome
MONDO:0009799	HPGD	P15428	1.1.1.- 1.1.1.232 1.1.1.141	R-HSA-9018676 R-HSA-9018676 Reactome Name: Biosynthesis of D-series resolvins See in Reactome R-HSA-9018896 R-HSA-9018896 Reactome Name: Biosynthesis of E-series 18(S)-resolvins See in Reactome R-HSA-2162123 R-HSA-2162123 Reactome Name: Synthesis of Prostaglandins (PG) and Thromboxanes (TX) See in Reactome R-HSA-2142700 R-HSA-2142700 Reactome Name: Synthesis of Lipoxins (LX) See in Reactome	R-HSA-9018677 R-HSA-9018677 Reactome Name: Biosynthesis of DHA-derived SPMs See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9018678 R-HSA-9018678 Reactome Name: Biosynthesis of specialized proresolving mediators (SPMs) See in Reactome R-HSA-9018679 R-HSA-9018679 Reactome Name: Biosynthesis of EPA-derived SPMs See in Reactome	Metabolism	R-HSA-2161662 ( R-HSA-2162123 ) R-HSA-2161662 Reaction Name: PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD See in Reactome R-HSA-2161779 ( R-HSA-2142700 ) R-HSA-2161779 Reaction Name: LXA4 is oxidised to 15k-LXA4 by HPGD See in Reactome R-HSA-9023968 ( R-HSA-9018896 ) R-HSA-9023968 Reaction Name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 See in Reactome R-HSA-9024766 ( R-HSA-9018676 ) R-HSA-9024766 Reaction Name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 See in Reactome
MONDO:0015466	HPGD	P15428	1.1.1.- 1.1.1.232 1.1.1.141	R-HSA-9018676 R-HSA-9018676 Reactome Name: Biosynthesis of D-series resolvins See in Reactome R-HSA-9018896 R-HSA-9018896 Reactome Name: Biosynthesis of E-series 18(S)-resolvins See in Reactome R-HSA-2162123 R-HSA-2162123 Reactome Name: Synthesis of Prostaglandins (PG) and Thromboxanes (TX) See in Reactome R-HSA-2142700 R-HSA-2142700 Reactome Name: Synthesis of Lipoxins (LX) See in Reactome	R-HSA-9018677 R-HSA-9018677 Reactome Name: Biosynthesis of DHA-derived SPMs See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9018678 R-HSA-9018678 Reactome Name: Biosynthesis of specialized proresolving mediators (SPMs) See in Reactome R-HSA-9018679 R-HSA-9018679 Reactome Name: Biosynthesis of EPA-derived SPMs See in Reactome	Metabolism	R-HSA-2161662 ( R-HSA-2162123 ) R-HSA-2161662 Reaction Name: PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD See in Reactome R-HSA-2161779 ( R-HSA-2142700 ) R-HSA-2161779 Reaction Name: LXA4 is oxidised to 15k-LXA4 by HPGD See in Reactome R-HSA-9023968 ( R-HSA-9018896 ) R-HSA-9023968 Reaction Name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 See in Reactome R-HSA-9024766 ( R-HSA-9018676 ) R-HSA-9024766 Reaction Name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 See in Reactome
MONDO:0024546	HPGD	P15428	1.1.1.- 1.1.1.232 1.1.1.141	R-HSA-9018676 R-HSA-9018676 Reactome Name: Biosynthesis of D-series resolvins See in Reactome R-HSA-9018896 R-HSA-9018896 Reactome Name: Biosynthesis of E-series 18(S)-resolvins See in Reactome R-HSA-2162123 R-HSA-2162123 Reactome Name: Synthesis of Prostaglandins (PG) and Thromboxanes (TX) See in Reactome R-HSA-2142700 R-HSA-2142700 Reactome Name: Synthesis of Lipoxins (LX) See in Reactome	R-HSA-9018677 R-HSA-9018677 Reactome Name: Biosynthesis of DHA-derived SPMs See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9018678 R-HSA-9018678 Reactome Name: Biosynthesis of specialized proresolving mediators (SPMs) See in Reactome R-HSA-9018679 R-HSA-9018679 Reactome Name: Biosynthesis of EPA-derived SPMs See in Reactome	Metabolism	R-HSA-2161662 ( R-HSA-2162123 ) R-HSA-2161662 Reaction Name: PGD2/E2/F2a is oxidised to 15k-PGD2/E2/F2a by HPGD See in Reactome R-HSA-2161779 ( R-HSA-2142700 ) R-HSA-2161779 Reaction Name: LXA4 is oxidised to 15k-LXA4 by HPGD See in Reactome R-HSA-9023968 ( R-HSA-9018896 ) R-HSA-9023968 Reaction Name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 See in Reactome R-HSA-9024766 ( R-HSA-9018676 ) R-HSA-9024766 Reaction Name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 See in Reactome