DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-2160916)

Number of enzymes:	4
Number of disease:	11
Number of reactomes:	6
Number of reactions:	15

Search results (Reactome ID: R-HSA-2160916)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009369	GUSB	P08236	3.2.1.31	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-2024096 R-HSA-2024096 Reactome Name: HS-GAG degradation See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1638091 R-HSA-1638091 Reactome Name: Heparan sulfate/heparin (HS-GAG) metabolism See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome	Immune System Metabolism	R-HSA-1678854 ( R-HSA-2024096 ) R-HSA-1678854 Reaction Name: GUSB tetramer hydrolyses CS/HS precursor See in Reactome R-HSA-2162226 ( R-HSA-2160916 ) R-HSA-2162226 Reaction Name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc See in Reactome R-HSA-2162227 ( R-HSA-2160916 ) R-HSA-2162227 Reaction Name: GUSB tetramer hydrolyses (HA)2 See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome
MONDO:0009661	GUSB	P08236	3.2.1.31	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-2024096 R-HSA-2024096 Reactome Name: HS-GAG degradation See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1638091 R-HSA-1638091 Reactome Name: Heparan sulfate/heparin (HS-GAG) metabolism See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome	Immune System Metabolism	R-HSA-1678854 ( R-HSA-2024096 ) R-HSA-1678854 Reaction Name: GUSB tetramer hydrolyses CS/HS precursor See in Reactome R-HSA-2162226 ( R-HSA-2160916 ) R-HSA-2162226 Reaction Name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc See in Reactome R-HSA-2162227 ( R-HSA-2160916 ) R-HSA-2162227 Reaction Name: GUSB tetramer hydrolyses (HA)2 See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome
MONDO:0009662	GUSB	P08236	3.2.1.31	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-2024096 R-HSA-2024096 Reactome Name: HS-GAG degradation See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1638091 R-HSA-1638091 Reactome Name: Heparan sulfate/heparin (HS-GAG) metabolism See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome	Immune System Metabolism	R-HSA-1678854 ( R-HSA-2024096 ) R-HSA-1678854 Reaction Name: GUSB tetramer hydrolyses CS/HS precursor See in Reactome R-HSA-2162226 ( R-HSA-2160916 ) R-HSA-2162226 Reaction Name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc See in Reactome R-HSA-2162227 ( R-HSA-2160916 ) R-HSA-2162227 Reaction Name: GUSB tetramer hydrolyses (HA)2 See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-6800434 ( R-HSA-6798695 ) R-HSA-6800434 Reaction Name: Exocytosis of ficolin-rich granule lumen proteins See in Reactome
MONDO:0011093	HYAL1	Q12794	3.2.1.35	R-HSA-2024101 R-HSA-2024101 Reactome Name: CS/DS degradation See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-1793185 R-HSA-1793185 Reactome Name: Chondroitin sulfate/dermatan sulfate metabolism See in Reactome	Metabolism	R-HSA-1793209 ( R-HSA-2024101 ) R-HSA-1793209 Reaction Name: HYAL1 hydrolyses Chondroitin chains See in Reactome R-HSA-2160874 ( R-HSA-2160916 ) R-HSA-2160874 Reaction Name: HYAL1 hydrolyses (HA)50 See in Reactome
MONDO:0017721	HEXB	P07686	3.2.1.52	R-HSA-2022857 R-HSA-2022857 Reactome Name: Keratan sulfate degradation See in Reactome R-HSA-2024101 R-HSA-2024101 Reactome Name: CS/DS degradation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-1638074 R-HSA-1638074 Reactome Name: Keratan sulfate/keratin metabolism See in Reactome R-HSA-1793185 R-HSA-1793185 Reactome Name: Chondroitin sulfate/dermatan sulfate metabolism See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome	Immune System Metabolism	R-HSA-1605595 ( R-HSA-1660662 ) R-HSA-1605595 Reaction Name: Hexosaminidase A cleaves GalNAc from GM2 to form GM3 See in Reactome R-HSA-1605632 ( R-HSA-1660662 ) R-HSA-1605632 Reaction Name: Both hexosaminidase A and B can cleave GalNAc from globoside See in Reactome R-HSA-1638053 ( R-HSA-2022857 ) R-HSA-1638053 Reaction Name: HEXA cleaves the terminal GalNAc from keratan sulfate See in Reactome R-HSA-2105001 ( R-HSA-2024101 ) R-HSA-2105001 Reaction Name: HEXA cleaves the terminal GalNAc from DS See in Reactome R-HSA-2162225 ( R-HSA-2160916 ) R-HSA-2162225 Reaction Name: HEXA cleaves the terminal GalNAc from small HA fragments See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-9638075 ( R-HSA-2024101 ) R-HSA-9638075 Reaction Name: HEXB cleaves the terminal GalNAc from DS See in Reactome R-HSA-9638076 ( R-HSA-2160916 ) R-HSA-9638076 Reaction Name: HEXB cleaves the terminal GalNAc from small HA fragments See in Reactome R-HSA-9638078 ( R-HSA-2022857 ) R-HSA-9638078 Reaction Name: HEXB cleaves the terminal GalNAc from keratan sulfate See in Reactome
MONDO:0017722	HEXB	P07686	3.2.1.52	R-HSA-2022857 R-HSA-2022857 Reactome Name: Keratan sulfate degradation See in Reactome R-HSA-2024101 R-HSA-2024101 Reactome Name: CS/DS degradation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-1638074 R-HSA-1638074 Reactome Name: Keratan sulfate/keratin metabolism See in Reactome R-HSA-1793185 R-HSA-1793185 Reactome Name: Chondroitin sulfate/dermatan sulfate metabolism See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome	Immune System Metabolism	R-HSA-1605595 ( R-HSA-1660662 ) R-HSA-1605595 Reaction Name: Hexosaminidase A cleaves GalNAc from GM2 to form GM3 See in Reactome R-HSA-1605632 ( R-HSA-1660662 ) R-HSA-1605632 Reaction Name: Both hexosaminidase A and B can cleave GalNAc from globoside See in Reactome R-HSA-1638053 ( R-HSA-2022857 ) R-HSA-1638053 Reaction Name: HEXA cleaves the terminal GalNAc from keratan sulfate See in Reactome R-HSA-2105001 ( R-HSA-2024101 ) R-HSA-2105001 Reaction Name: HEXA cleaves the terminal GalNAc from DS See in Reactome R-HSA-2162225 ( R-HSA-2160916 ) R-HSA-2162225 Reaction Name: HEXA cleaves the terminal GalNAc from small HA fragments See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-9638075 ( R-HSA-2024101 ) R-HSA-9638075 Reaction Name: HEXB cleaves the terminal GalNAc from DS See in Reactome R-HSA-9638076 ( R-HSA-2160916 ) R-HSA-9638076 Reaction Name: HEXB cleaves the terminal GalNAc from small HA fragments See in Reactome R-HSA-9638078 ( R-HSA-2022857 ) R-HSA-9638078 Reaction Name: HEXB cleaves the terminal GalNAc from keratan sulfate See in Reactome
MONDO:0017723	HEXB	P07686	3.2.1.52	R-HSA-2022857 R-HSA-2022857 Reactome Name: Keratan sulfate degradation See in Reactome R-HSA-2024101 R-HSA-2024101 Reactome Name: CS/DS degradation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-1638074 R-HSA-1638074 Reactome Name: Keratan sulfate/keratin metabolism See in Reactome R-HSA-1793185 R-HSA-1793185 Reactome Name: Chondroitin sulfate/dermatan sulfate metabolism See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome	Immune System Metabolism	R-HSA-1605595 ( R-HSA-1660662 ) R-HSA-1605595 Reaction Name: Hexosaminidase A cleaves GalNAc from GM2 to form GM3 See in Reactome R-HSA-1605632 ( R-HSA-1660662 ) R-HSA-1605632 Reaction Name: Both hexosaminidase A and B can cleave GalNAc from globoside See in Reactome R-HSA-1638053 ( R-HSA-2022857 ) R-HSA-1638053 Reaction Name: HEXA cleaves the terminal GalNAc from keratan sulfate See in Reactome R-HSA-2105001 ( R-HSA-2024101 ) R-HSA-2105001 Reaction Name: HEXA cleaves the terminal GalNAc from DS See in Reactome R-HSA-2162225 ( R-HSA-2160916 ) R-HSA-2162225 Reaction Name: HEXA cleaves the terminal GalNAc from small HA fragments See in Reactome R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-9638075 ( R-HSA-2024101 ) R-HSA-9638075 Reaction Name: HEXB cleaves the terminal GalNAc from DS See in Reactome R-HSA-9638076 ( R-HSA-2160916 ) R-HSA-9638076 Reaction Name: HEXB cleaves the terminal GalNAc from small HA fragments See in Reactome R-HSA-9638078 ( R-HSA-2022857 ) R-HSA-9638078 Reaction Name: HEXB cleaves the terminal GalNAc from keratan sulfate See in Reactome
MONDO:0017724	HEXA	P06865	3.2.1.52	R-HSA-2022857 R-HSA-2022857 Reactome Name: Keratan sulfate degradation See in Reactome R-HSA-2024101 R-HSA-2024101 Reactome Name: CS/DS degradation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-1638074 R-HSA-1638074 Reactome Name: Keratan sulfate/keratin metabolism See in Reactome R-HSA-1793185 R-HSA-1793185 Reactome Name: Chondroitin sulfate/dermatan sulfate metabolism See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome	Metabolism	R-HSA-1605595 ( R-HSA-1660662 ) R-HSA-1605595 Reaction Name: Hexosaminidase A cleaves GalNAc from GM2 to form GM3 See in Reactome R-HSA-1605632 ( R-HSA-1660662 ) R-HSA-1605632 Reaction Name: Both hexosaminidase A and B can cleave GalNAc from globoside See in Reactome R-HSA-1638053 ( R-HSA-2022857 ) R-HSA-1638053 Reaction Name: HEXA cleaves the terminal GalNAc from keratan sulfate See in Reactome R-HSA-2105001 ( R-HSA-2024101 ) R-HSA-2105001 Reaction Name: HEXA cleaves the terminal GalNAc from DS See in Reactome R-HSA-2162225 ( R-HSA-2160916 ) R-HSA-2162225 Reaction Name: HEXA cleaves the terminal GalNAc from small HA fragments See in Reactome
MONDO:0017725	HEXA	P06865	3.2.1.52	R-HSA-2022857 R-HSA-2022857 Reactome Name: Keratan sulfate degradation See in Reactome R-HSA-2024101 R-HSA-2024101 Reactome Name: CS/DS degradation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-1638074 R-HSA-1638074 Reactome Name: Keratan sulfate/keratin metabolism See in Reactome R-HSA-1793185 R-HSA-1793185 Reactome Name: Chondroitin sulfate/dermatan sulfate metabolism See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome	Metabolism	R-HSA-1605595 ( R-HSA-1660662 ) R-HSA-1605595 Reaction Name: Hexosaminidase A cleaves GalNAc from GM2 to form GM3 See in Reactome R-HSA-1605632 ( R-HSA-1660662 ) R-HSA-1605632 Reaction Name: Both hexosaminidase A and B can cleave GalNAc from globoside See in Reactome R-HSA-1638053 ( R-HSA-2022857 ) R-HSA-1638053 Reaction Name: HEXA cleaves the terminal GalNAc from keratan sulfate See in Reactome R-HSA-2105001 ( R-HSA-2024101 ) R-HSA-2105001 Reaction Name: HEXA cleaves the terminal GalNAc from DS See in Reactome R-HSA-2162225 ( R-HSA-2160916 ) R-HSA-2162225 Reaction Name: HEXA cleaves the terminal GalNAc from small HA fragments See in Reactome
MONDO:0017726	HEXA	P06865	3.2.1.52	R-HSA-2022857 R-HSA-2022857 Reactome Name: Keratan sulfate degradation See in Reactome R-HSA-2024101 R-HSA-2024101 Reactome Name: CS/DS degradation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-1638074 R-HSA-1638074 Reactome Name: Keratan sulfate/keratin metabolism See in Reactome R-HSA-1793185 R-HSA-1793185 Reactome Name: Chondroitin sulfate/dermatan sulfate metabolism See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome	Metabolism	R-HSA-1605595 ( R-HSA-1660662 ) R-HSA-1605595 Reaction Name: Hexosaminidase A cleaves GalNAc from GM2 to form GM3 See in Reactome R-HSA-1605632 ( R-HSA-1660662 ) R-HSA-1605632 Reaction Name: Both hexosaminidase A and B can cleave GalNAc from globoside See in Reactome R-HSA-1638053 ( R-HSA-2022857 ) R-HSA-1638053 Reaction Name: HEXA cleaves the terminal GalNAc from keratan sulfate See in Reactome R-HSA-2105001 ( R-HSA-2024101 ) R-HSA-2105001 Reaction Name: HEXA cleaves the terminal GalNAc from DS See in Reactome R-HSA-2162225 ( R-HSA-2160916 ) R-HSA-2162225 Reaction Name: HEXA cleaves the terminal GalNAc from small HA fragments See in Reactome
MONDO:0017728	HEXA	P06865	3.2.1.52	R-HSA-2022857 R-HSA-2022857 Reactome Name: Keratan sulfate degradation See in Reactome R-HSA-2024101 R-HSA-2024101 Reactome Name: CS/DS degradation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-1638074 R-HSA-1638074 Reactome Name: Keratan sulfate/keratin metabolism See in Reactome R-HSA-1793185 R-HSA-1793185 Reactome Name: Chondroitin sulfate/dermatan sulfate metabolism See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome	Metabolism	R-HSA-1605595 ( R-HSA-1660662 ) R-HSA-1605595 Reaction Name: Hexosaminidase A cleaves GalNAc from GM2 to form GM3 See in Reactome R-HSA-1605632 ( R-HSA-1660662 ) R-HSA-1605632 Reaction Name: Both hexosaminidase A and B can cleave GalNAc from globoside See in Reactome R-HSA-1638053 ( R-HSA-2022857 ) R-HSA-1638053 Reaction Name: HEXA cleaves the terminal GalNAc from keratan sulfate See in Reactome R-HSA-2105001 ( R-HSA-2024101 ) R-HSA-2105001 Reaction Name: HEXA cleaves the terminal GalNAc from DS See in Reactome R-HSA-2162225 ( R-HSA-2160916 ) R-HSA-2162225 Reaction Name: HEXA cleaves the terminal GalNAc from small HA fragments See in Reactome