DAR - Bologna Biocomputing Group

Search results (Reactome ID: R-HSA-211976)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0001071	CYP27A1	Q02318	1.14.15.15	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-193807 R-HSA-193807 Reactome Name: Synthesis of bile acids and bile salts via 27-hydroxycholesterol See in Reactome R-HSA-193368 R-HSA-193368 Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol See in Reactome R-HSA-193775 R-HSA-193775 Reactome Name: Synthesis of bile acids and bile salts via 24-hydroxycholesterol See in Reactome	R-HSA-194068 R-HSA-194068 Reactome Name: Bile acid and bile salt metabolism See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-192105 R-HSA-192105 Reactome Name: Synthesis of bile acids and bile salts See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-191999 ( R-HSA-192105; R-HSA-193368 ) R-HSA-191999 Reaction Name: CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol See in Reactome R-HSA-192042 ( R-HSA-192105; R-HSA-193368 ) R-HSA-192042 Reaction Name: 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al See in Reactome R-HSA-192054 ( R-HSA-192105; R-HSA-193368 ) R-HSA-192054 Reaction Name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) See in Reactome R-HSA-192123 ( R-HSA-192105; R-HSA-193807; R-HSA-211976 ) R-HSA-192123 Reaction Name: CYP27A1 27-hydroxylates CHOL See in Reactome R-HSA-193393 ( R-HSA-192105; R-HSA-193368 ) R-HSA-193393 Reaction Name: 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol See in Reactome R-HSA-193460 ( R-HSA-192105; R-HSA-193368 ) R-HSA-193460 Reaction Name: 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) See in Reactome R-HSA-193497 ( R-HSA-192105; R-HSA-193368 ) R-HSA-193497 Reaction Name: 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al See in Reactome R-HSA-193713 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193713 Reaction Name: 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) See in Reactome R-HSA-193719 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193719 Reaction Name: 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al See in Reactome R-HSA-193737 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193737 Reaction Name: 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) See in Reactome R-HSA-193780 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193780 Reaction Name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al See in Reactome R-HSA-193787 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193787 Reaction Name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol See in Reactome R-HSA-193792 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193792 Reaction Name: CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol See in Reactome
MONDO:0007080	CYP11B1	P15538	1.14.15.4	R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193997 ( R-HSA-194002; R-HSA-211976 ) R-HSA-193997 Reaction Name: CYP11B1 oxidises 11DCORT See in Reactome
MONDO:0007080	CYP11B2	P19099	1.14.15.5 1.14.15.4	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193965 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193965 Reaction Name: CYP11B2 oxidises 18HCORST to ALDO See in Reactome R-HSA-193995 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193995 Reaction Name: CYP11B2 18-hydroxylates CORST to 18HCORST See in Reactome R-HSA-193997 ( R-HSA-194002; R-HSA-211976 ) R-HSA-193997 Reaction Name: CYP11B1 oxidises 11DCORT See in Reactome R-HSA-194017 ( R-HSA-193993; R-HSA-211976 ) R-HSA-194017 Reaction Name: CYP11B2 oxidises 11DCORST to CORST See in Reactome
MONDO:0007664	CYP1B1	Q16678	4.2.1.152 1.14.14.1	R-HSA-2142816 R-HSA-2142816 Reactome Name: Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2142670 R-HSA-2142670 Reactome Name: Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-211951 ( R-HSA-211976 ) R-HSA-211951 Reaction Name: CYP1B1 4-hydroxylates EST17b See in Reactome R-HSA-2161795 ( R-HSA-2142816 ) R-HSA-2161795 Reaction Name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) See in Reactome R-HSA-2161814 ( R-HSA-2142816 ) R-HSA-2161814 Reaction Name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) See in Reactome R-HSA-2161890 ( R-HSA-2142670 ) R-HSA-2161890 Reaction Name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) See in Reactome R-HSA-2161899 ( R-HSA-2142670 ) R-HSA-2161899 Reaction Name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) See in Reactome R-HSA-2161940 ( R-HSA-2142816 ) R-HSA-2161940 Reaction Name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) See in Reactome
MONDO:0007690	CYP19A1	P11511	1.14.14.14	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-193144 R-HSA-193144 Reactome Name: Estrogen biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193060 ( R-HSA-193144; R-HSA-211976 ) R-HSA-193060 Reaction Name: CYP19A1 hydroxylates ANDST to E1 See in Reactome R-HSA-193143 ( R-HSA-193144 ) R-HSA-193143 Reaction Name: CYP19A1 hydroxylates TEST to EST17b See in Reactome
MONDO:0008729	CYP11B1	P15538	1.14.15.4	R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193997 ( R-HSA-194002; R-HSA-211976 ) R-HSA-193997 Reaction Name: CYP11B1 oxidises 11DCORT See in Reactome
MONDO:0008751	CYP11B2	P19099	1.14.15.5 1.14.15.4	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193965 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193965 Reaction Name: CYP11B2 oxidises 18HCORST to ALDO See in Reactome R-HSA-193995 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193995 Reaction Name: CYP11B2 18-hydroxylates CORST to 18HCORST See in Reactome R-HSA-193997 ( R-HSA-194002; R-HSA-211976 ) R-HSA-193997 Reaction Name: CYP11B1 oxidises 11DCORT See in Reactome R-HSA-194017 ( R-HSA-193993; R-HSA-211976 ) R-HSA-194017 Reaction Name: CYP11B2 oxidises 11DCORST to CORST See in Reactome
MONDO:0008865	CYP4V2	Q6ZWL3	1.14.14.79 1.14.14.80	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2453902 R-HSA-2453902 Reactome Name: The canonical retinoid cycle in rods (twilight vision) See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Sensory Perception Metabolism	R-HSA-6786239 ( R-HSA-211976; R-HSA-2453902 ) R-HSA-6786239 Reaction Name: CYP4V2 omega-hydroxylates DHA to HDoHE See in Reactome
MONDO:0008948	CYP27A1	Q02318	1.14.15.15	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-193807 R-HSA-193807 Reactome Name: Synthesis of bile acids and bile salts via 27-hydroxycholesterol See in Reactome R-HSA-193368 R-HSA-193368 Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol See in Reactome R-HSA-193775 R-HSA-193775 Reactome Name: Synthesis of bile acids and bile salts via 24-hydroxycholesterol See in Reactome	R-HSA-194068 R-HSA-194068 Reactome Name: Bile acid and bile salt metabolism See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-192105 R-HSA-192105 Reactome Name: Synthesis of bile acids and bile salts See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-191999 ( R-HSA-192105; R-HSA-193368 ) R-HSA-191999 Reaction Name: CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol See in Reactome R-HSA-192042 ( R-HSA-192105; R-HSA-193368 ) R-HSA-192042 Reaction Name: 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al See in Reactome R-HSA-192054 ( R-HSA-192105; R-HSA-193368 ) R-HSA-192054 Reaction Name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) See in Reactome R-HSA-192123 ( R-HSA-192105; R-HSA-193807; R-HSA-211976 ) R-HSA-192123 Reaction Name: CYP27A1 27-hydroxylates CHOL See in Reactome R-HSA-193393 ( R-HSA-192105; R-HSA-193368 ) R-HSA-193393 Reaction Name: 5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol See in Reactome R-HSA-193460 ( R-HSA-192105; R-HSA-193368 ) R-HSA-193460 Reaction Name: 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) See in Reactome R-HSA-193497 ( R-HSA-192105; R-HSA-193368 ) R-HSA-193497 Reaction Name: 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al See in Reactome R-HSA-193713 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193713 Reaction Name: 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA) See in Reactome R-HSA-193719 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193719 Reaction Name: 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al See in Reactome R-HSA-193737 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193737 Reaction Name: 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) See in Reactome R-HSA-193780 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193780 Reaction Name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al See in Reactome R-HSA-193787 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193787 Reaction Name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol See in Reactome R-HSA-193792 ( R-HSA-192105; R-HSA-193775 ) R-HSA-193792 Reaction Name: CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol See in Reactome
MONDO:0009277	CYP1B1	Q16678	4.2.1.152 1.14.14.1	R-HSA-2142816 R-HSA-2142816 Reactome Name: Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2142670 R-HSA-2142670 Reactome Name: Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-211951 ( R-HSA-211976 ) R-HSA-211951 Reaction Name: CYP1B1 4-hydroxylates EST17b See in Reactome R-HSA-2161795 ( R-HSA-2142816 ) R-HSA-2161795 Reaction Name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) See in Reactome R-HSA-2161814 ( R-HSA-2142816 ) R-HSA-2161814 Reaction Name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) See in Reactome R-HSA-2161890 ( R-HSA-2142670 ) R-HSA-2161890 Reaction Name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) See in Reactome R-HSA-2161899 ( R-HSA-2142670 ) R-HSA-2161899 Reaction Name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) See in Reactome R-HSA-2161940 ( R-HSA-2142816 ) R-HSA-2161940 Reaction Name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) See in Reactome
MONDO:0010047	CYP7B1	O75881	1.14.14.26 1.14.14.29	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-193807 R-HSA-193807 Reactome Name: Synthesis of bile acids and bile salts via 27-hydroxycholesterol See in Reactome R-HSA-193368 R-HSA-193368 Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol See in Reactome R-HSA-192105 R-HSA-192105 Reactome Name: Synthesis of bile acids and bile salts See in Reactome	R-HSA-194068 R-HSA-194068 Reactome Name: Bile acid and bile salt metabolism See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-191972 ( R-HSA-192105; R-HSA-193807 ) R-HSA-191972 Reaction Name: 27-hydroxycholesterol is 7alpha-hydroxylated See in Reactome R-HSA-192051 ( R-HSA-192105; R-HSA-193368; R-HSA-211976 ) R-HSA-192051 Reaction Name: CYP7A1 7-hydroxylates CHOL See in Reactome R-HSA-192065 ( R-HSA-192105; R-HSA-211976 ) R-HSA-192065 Reaction Name: CYP7B1 7-hydroxylates 25OH-CHOL See in Reactome
MONDO:0010968	CYP1B1	Q16678	4.2.1.152 1.14.14.1	R-HSA-2142816 R-HSA-2142816 Reactome Name: Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2142670 R-HSA-2142670 Reactome Name: Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-211951 ( R-HSA-211976 ) R-HSA-211951 Reaction Name: CYP1B1 4-hydroxylates EST17b See in Reactome R-HSA-2161795 ( R-HSA-2142816 ) R-HSA-2161795 Reaction Name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) See in Reactome R-HSA-2161814 ( R-HSA-2142816 ) R-HSA-2161814 Reaction Name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) See in Reactome R-HSA-2161890 ( R-HSA-2142670 ) R-HSA-2161890 Reaction Name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) See in Reactome R-HSA-2161899 ( R-HSA-2142670 ) R-HSA-2161899 Reaction Name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) See in Reactome R-HSA-2161940 ( R-HSA-2142816 ) R-HSA-2161940 Reaction Name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) See in Reactome
MONDO:0011414	CYP1B1	Q16678	4.2.1.152 1.14.14.1	R-HSA-2142816 R-HSA-2142816 Reactome Name: Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2142670 R-HSA-2142670 Reactome Name: Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-211951 ( R-HSA-211976 ) R-HSA-211951 Reaction Name: CYP1B1 4-hydroxylates EST17b See in Reactome R-HSA-2161795 ( R-HSA-2142816 ) R-HSA-2161795 Reaction Name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) See in Reactome R-HSA-2161814 ( R-HSA-2142816 ) R-HSA-2161814 Reaction Name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) See in Reactome R-HSA-2161890 ( R-HSA-2142670 ) R-HSA-2161890 Reaction Name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) See in Reactome R-HSA-2161899 ( R-HSA-2142670 ) R-HSA-2161899 Reaction Name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) See in Reactome R-HSA-2161940 ( R-HSA-2142816 ) R-HSA-2161940 Reaction Name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) See in Reactome
MONDO:0012524	CYP11B2	P19099	1.14.15.5 1.14.15.4	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193965 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193965 Reaction Name: CYP11B2 oxidises 18HCORST to ALDO See in Reactome R-HSA-193995 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193995 Reaction Name: CYP11B2 18-hydroxylates CORST to 18HCORST See in Reactome R-HSA-193997 ( R-HSA-194002; R-HSA-211976 ) R-HSA-193997 Reaction Name: CYP11B1 oxidises 11DCORT See in Reactome R-HSA-194017 ( R-HSA-193993; R-HSA-211976 ) R-HSA-194017 Reaction Name: CYP11B2 oxidises 11DCORST to CORST See in Reactome
MONDO:0013301	CYP19A1	P11511	1.14.14.14	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-193144 R-HSA-193144 Reactome Name: Estrogen biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193060 ( R-HSA-193144; R-HSA-211976 ) R-HSA-193060 Reaction Name: CYP19A1 hydroxylates ANDST to E1 See in Reactome R-HSA-193143 ( R-HSA-193144 ) R-HSA-193143 Reaction Name: CYP19A1 hydroxylates TEST to EST17b See in Reactome
MONDO:0013400	CYP11A1	P05108	1.14.15.6	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-196108 R-HSA-196108 Reactome Name: Pregnenolone biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193054 ( R-HSA-196108 ) R-HSA-193054 Reaction Name: Oxidation of cholesterol to 22beta-hydroxycholesterol See in Reactome R-HSA-193065 ( R-HSA-196108 ) R-HSA-193065 Reaction Name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol See in Reactome R-HSA-193101 ( R-HSA-196108; R-HSA-211976 ) R-HSA-193101 Reaction Name: CYP11A1 cleaves 20a,22b-DHCHOL See in Reactome
MONDO:0013439	CYP7B1	O75881	1.14.14.26 1.14.14.29	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-193807 R-HSA-193807 Reactome Name: Synthesis of bile acids and bile salts via 27-hydroxycholesterol See in Reactome R-HSA-193368 R-HSA-193368 Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol See in Reactome R-HSA-192105 R-HSA-192105 Reactome Name: Synthesis of bile acids and bile salts See in Reactome	R-HSA-194068 R-HSA-194068 Reactome Name: Bile acid and bile salt metabolism See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-191972 ( R-HSA-192105; R-HSA-193807 ) R-HSA-191972 Reaction Name: 27-hydroxycholesterol is 7alpha-hydroxylated See in Reactome R-HSA-192051 ( R-HSA-192105; R-HSA-193368; R-HSA-211976 ) R-HSA-192051 Reaction Name: CYP7A1 7-hydroxylates CHOL See in Reactome R-HSA-192065 ( R-HSA-192105; R-HSA-211976 ) R-HSA-192065 Reaction Name: CYP7B1 7-hydroxylates 25OH-CHOL See in Reactome
MONDO:0015016	CYP1B1	Q16678	4.2.1.152 1.14.14.1	R-HSA-2142816 R-HSA-2142816 Reactome Name: Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2142670 R-HSA-2142670 Reactome Name: Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Metabolism	R-HSA-211951 ( R-HSA-211976 ) R-HSA-211951 Reaction Name: CYP1B1 4-hydroxylates EST17b See in Reactome R-HSA-2161795 ( R-HSA-2142816 ) R-HSA-2161795 Reaction Name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) See in Reactome R-HSA-2161814 ( R-HSA-2142816 ) R-HSA-2161814 Reaction Name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) See in Reactome R-HSA-2161890 ( R-HSA-2142670 ) R-HSA-2161890 Reaction Name: Arachidonic acid is epoxidated to 5,6-EET by CYP(4) See in Reactome R-HSA-2161899 ( R-HSA-2142670 ) R-HSA-2161899 Reaction Name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) See in Reactome R-HSA-2161940 ( R-HSA-2142816 ) R-HSA-2161940 Reaction Name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) See in Reactome
MONDO:0016203	CYP7A1	P22680	1.14.14.26 1.14.14.23	R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-193807 R-HSA-193807 Reactome Name: Synthesis of bile acids and bile salts via 27-hydroxycholesterol See in Reactome R-HSA-193368 R-HSA-193368 Reactome Name: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol See in Reactome R-HSA-192105 R-HSA-192105 Reactome Name: Synthesis of bile acids and bile salts See in Reactome	R-HSA-194068 R-HSA-194068 Reactome Name: Bile acid and bile salt metabolism See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-191972 ( R-HSA-192105; R-HSA-193807 ) R-HSA-191972 Reaction Name: 27-hydroxycholesterol is 7alpha-hydroxylated See in Reactome R-HSA-192051 ( R-HSA-192105; R-HSA-193368; R-HSA-211976 ) R-HSA-192051 Reaction Name: CYP7A1 7-hydroxylates CHOL See in Reactome R-HSA-192065 ( R-HSA-192105; R-HSA-211976 ) R-HSA-192065 Reaction Name: CYP7B1 7-hydroxylates 25OH-CHOL See in Reactome R-HSA-1989746 ( R-HSA-1989781 ) R-HSA-1989746 Reaction Name: Expression of CYP7A1 See in Reactome
MONDO:0017337	CYP11A1	P05108	1.14.15.6	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-196108 R-HSA-196108 Reactome Name: Pregnenolone biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193054 ( R-HSA-196108 ) R-HSA-193054 Reaction Name: Oxidation of cholesterol to 22beta-hydroxycholesterol See in Reactome R-HSA-193065 ( R-HSA-196108 ) R-HSA-193065 Reaction Name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol See in Reactome R-HSA-193101 ( R-HSA-196108; R-HSA-211976 ) R-HSA-193101 Reaction Name: CYP11A1 cleaves 20a,22b-DHCHOL See in Reactome
MONDO:0017839	CYP21A2	P08686	1.14.14.16	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193964 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193964 Reaction Name: CYP21A2 21-hydroxylates PROG See in Reactome R-HSA-193981 ( R-HSA-194002 ) R-HSA-193981 Reaction Name: CYP21A2 oxidises 17HPROG See in Reactome
MONDO:0017840	CYP21A2	P08686	1.14.14.16	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193964 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193964 Reaction Name: CYP21A2 21-hydroxylates PROG See in Reactome R-HSA-193981 ( R-HSA-194002 ) R-HSA-193981 Reaction Name: CYP21A2 oxidises 17HPROG See in Reactome
MONDO:0019200	CYP4V2	Q6ZWL3	1.14.14.79 1.14.14.80	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2453902 R-HSA-2453902 Reactome Name: The canonical retinoid cycle in rods (twilight vision) See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Sensory Perception Metabolism	R-HSA-6786239 ( R-HSA-211976; R-HSA-2453902 ) R-HSA-6786239 Reaction Name: CYP4V2 omega-hydroxylates DHA to HDoHE See in Reactome
MONDO:0033853	CYP51A1	Q16850	1.14.14.154	R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome R-HSA-9619665 R-HSA-9619665 Reactome Name: EGR2 and SOX10-mediated initiation of Schwann cell myelination See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism Developmental Biology	R-HSA-1655847 ( R-HSA-2426168 ) R-HSA-1655847 Reaction Name: Expression of Lanosterol Demethylase (CYP51A1) See in Reactome R-HSA-194678 ( R-HSA-191273; R-HSA-211976 ) R-HSA-194678 Reaction Name: CYP51A1 demethylates LNSOL See in Reactome R-HSA-9621404 ( R-HSA-9619665 ) R-HSA-9621404 Reaction Name: CYP51A1 gene expression See in Reactome
MONDO:0034092	FDXR	P22570	1.18.1.6	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2395516 R-HSA-2395516 Reactome Name: Electron transport from NADPH to Ferredoxin See in Reactome R-HSA-196108 R-HSA-196108 Reactome Name: Pregnenolone biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1362409 R-HSA-1362409 Reactome Name: Mitochondrial iron-sulfur cluster biogenesis See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193054 ( R-HSA-196108 ) R-HSA-193054 Reaction Name: Oxidation of cholesterol to 22beta-hydroxycholesterol See in Reactome R-HSA-193065 ( R-HSA-196108 ) R-HSA-193065 Reaction Name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol See in Reactome R-HSA-193101 ( R-HSA-196108; R-HSA-211976 ) R-HSA-193101 Reaction Name: CYP11A1 cleaves 20a,22b-DHCHOL See in Reactome R-HSA-2395512 ( R-HSA-2395516 ) R-HSA-2395512 Reaction Name: FDXR transfers electrons to FDX1,2 (FDX1L) See in Reactome R-HSA-2395517 ( R-HSA-2395516 ) R-HSA-2395517 Reaction Name: NADPH transfers electrons to FDXR See in Reactome
MONDO:0060582	FDXR	P22570	1.18.1.6	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2395516 R-HSA-2395516 Reactome Name: Electron transport from NADPH to Ferredoxin See in Reactome R-HSA-196108 R-HSA-196108 Reactome Name: Pregnenolone biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1362409 R-HSA-1362409 Reactome Name: Mitochondrial iron-sulfur cluster biogenesis See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193054 ( R-HSA-196108 ) R-HSA-193054 Reaction Name: Oxidation of cholesterol to 22beta-hydroxycholesterol See in Reactome R-HSA-193065 ( R-HSA-196108 ) R-HSA-193065 Reaction Name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol See in Reactome R-HSA-193101 ( R-HSA-196108; R-HSA-211976 ) R-HSA-193101 Reaction Name: CYP11A1 cleaves 20a,22b-DHCHOL See in Reactome R-HSA-2395512 ( R-HSA-2395516 ) R-HSA-2395512 Reaction Name: FDXR transfers electrons to FDX1,2 (FDX1L) See in Reactome R-HSA-2395517 ( R-HSA-2395516 ) R-HSA-2395517 Reaction Name: NADPH transfers electrons to FDXR See in Reactome

Number of enzymes:	12
Number of disease:	25
Number of reactomes:	17
Number of reactions:	40

Search summary (Reactome ID: R-HSA-211976)

Search results (Reactome ID: R-HSA-211976)

MONDO:0001071

R-HSA-211976

R-HSA-193807

R-HSA-193368

R-HSA-193775

R-HSA-194068

R-HSA-211859

R-HSA-211897

R-HSA-211945

R-HSA-1430728

R-HSA-192105

R-HSA-556833

R-HSA-8957322

R-HSA-191999

R-HSA-192042

R-HSA-192054

R-HSA-192123

R-HSA-193393

R-HSA-193460

R-HSA-193497

R-HSA-193713

R-HSA-193719

R-HSA-193737

R-HSA-193780

R-HSA-193787

R-HSA-193792

MONDO:0007080

R-HSA-194002

R-HSA-211976

R-HSA-211897

R-HSA-211859

R-HSA-211945

R-HSA-1430728

R-HSA-556833

R-HSA-196071

R-HSA-8957322

R-HSA-193997

MONDO:0007080

R-HSA-211976

R-HSA-194002

R-HSA-193993

R-HSA-211897

R-HSA-211859

R-HSA-211945

R-HSA-1430728

R-HSA-556833

R-HSA-196071

R-HSA-8957322

R-HSA-193965

R-HSA-193995

R-HSA-193997

R-HSA-194017

MONDO:0007664

R-HSA-2142816

R-HSA-211976

R-HSA-2142670

R-HSA-211897

R-HSA-211859

R-HSA-211945

R-HSA-1430728

R-HSA-8978868

R-HSA-2142753

R-HSA-556833

R-HSA-211951

R-HSA-2161795

R-HSA-2161814

R-HSA-2161890

R-HSA-2161899

R-HSA-2161940

MONDO:0007690

R-HSA-211976

R-HSA-193144

R-HSA-211897

R-HSA-211859

R-HSA-211945

R-HSA-1430728

R-HSA-556833

R-HSA-196071