DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-211916)

Number of enzymes:	5
Number of disease:	6
Number of reactomes:	3
Number of reactions:	7

Search results (Reactome ID: R-HSA-211916)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007749	CYP24A1	Q07973	1.14.15.16	R-HSA-211916 R-HSA-211916 Reactome Name: Vitamins See in Reactome R-HSA-196791 R-HSA-196791 Reactome Name: Vitamin D (calciferol) metabolism See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-209765 ( R-HSA-196791 ) R-HSA-209765 Reaction Name: CYP24A1 hydroxylates 1,25(OH)2D, inactivating it See in Reactome R-HSA-211950 ( R-HSA-211916 ) R-HSA-211950 Reaction Name: CYP24A1 24-hydroxylates CTL See in Reactome
MONDO:0010810	CYP2R1	Q6VVX0	1.14.14.24	R-HSA-211916 R-HSA-211916 Reactome Name: Vitamins See in Reactome R-HSA-196791 R-HSA-196791 Reactome Name: Vitamin D (calciferol) metabolism See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-209845 ( R-HSA-196791; R-HSA-211916 ) R-HSA-209845 Reaction Name: CYP2R1 25-hydroxylates VD3 to 25(OH)D See in Reactome
MONDO:0013740	CYP26B1	Q9NR63	1.14.13.-	R-HSA-5365859 R-HSA-5365859 Reactome Name: RA biosynthesis pathway See in Reactome R-HSA-211916 R-HSA-211916 Reactome Name: Vitamins See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5362517 R-HSA-5362517 Reactome Name: Signaling by Retinoic Acid See in Reactome	Metabolism Signal Transduction	R-HSA-212007 ( R-HSA-211916 ) R-HSA-212007 Reaction Name: CYP26A1,B1 4-hydroxylate atRA See in Reactome R-HSA-5362525 ( R-HSA-5365859 ) R-HSA-5362525 Reaction Name: CYP26A1,B1,C1 4-hydroxylate atRA See in Reactome
MONDO:0013997	CYP26C1	Q6V0L0	1.14.-.-	R-HSA-5365859 R-HSA-5365859 Reactome Name: RA biosynthesis pathway See in Reactome R-HSA-211916 R-HSA-211916 Reactome Name: Vitamins See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5362517 R-HSA-5362517 Reactome Name: Signaling by Retinoic Acid See in Reactome	Metabolism Signal Transduction	R-HSA-211923 ( R-HSA-211916; R-HSA-5365859 ) R-HSA-211923 Reaction Name: CYP26C1 4-hydroxylates 9cRA See in Reactome R-HSA-212007 ( R-HSA-211916 ) R-HSA-212007 Reaction Name: CYP26A1,B1 4-hydroxylate atRA See in Reactome R-HSA-5362525 ( R-HSA-5365859 ) R-HSA-5362525 Reaction Name: CYP26A1,B1,C1 4-hydroxylate atRA See in Reactome
MONDO:0020723	CYP27B1	O15528	1.14.15.18	R-HSA-211916 R-HSA-211916 Reactome Name: Vitamins See in Reactome R-HSA-196791 R-HSA-196791 Reactome Name: Vitamin D (calciferol) metabolism See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-209868 ( R-HSA-196791; R-HSA-211916 ) R-HSA-209868 Reaction Name: CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D See in Reactome
MONDO:0020739	CYP24A1	Q07973	1.14.15.16	R-HSA-211916 R-HSA-211916 Reactome Name: Vitamins See in Reactome R-HSA-196791 R-HSA-196791 Reactome Name: Vitamin D (calciferol) metabolism See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-209765 ( R-HSA-196791 ) R-HSA-209765 Reaction Name: CYP24A1 hydroxylates 1,25(OH)2D, inactivating it See in Reactome R-HSA-211950 ( R-HSA-211916 ) R-HSA-211950 Reaction Name: CYP24A1 24-hydroxylates CTL See in Reactome