DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-196741)

Number of enzymes:	10
Number of disease:	15
Number of reactomes:	10
Number of reactions:	27

Search results (Reactome ID: R-HSA-196741)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007934	MMACHC	Q9Y4U1	2.5.1.151 1.16.1.6	R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-3095889 ( R-HSA-196741 ) R-HSA-3095889 Reaction Name: MMACHC dealkylates RCbl See in Reactome R-HSA-3149494 ( R-HSA-196741 ) R-HSA-3149494 Reaction Name: MMACHC:cob(II)alamin binds MMADHC See in Reactome R-HSA-3149519 ( R-HSA-196741 ) R-HSA-3149519 Reaction Name: MMACHC decyanates CNCbl See in Reactome R-HSA-3149563 ( R-HSA-196741 ) R-HSA-3149563 Reaction Name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria See in Reactome R-HSA-3204318 ( R-HSA-196741 ) R-HSA-3204318 Reaction Name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR See in Reactome R-HSA-9759549 ( R-HSA-196741 ) R-HSA-9759549 Reaction Name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin See in Reactome
MONDO:0008185	PRSS1	P07477	3.4.21.4	R-HSA-1592389 R-HSA-1592389 Reactome Name: Activation of Matrix Metalloproteinases See in Reactome R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome	R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1474228 R-HSA-1474228 Reactome Name: Degradation of the extracellular matrix See in Reactome	Extracellular matrix organization Metabolism	R-HSA-1592316 ( R-HSA-1592389 ) R-HSA-1592316 Reaction Name: Initial activation of proMMP1 See in Reactome R-HSA-1592371 ( R-HSA-1592389 ) R-HSA-1592371 Reaction Name: Initial activation of proMMP3 See in Reactome R-HSA-1592398 ( R-HSA-1592389 ) R-HSA-1592398 Reaction Name: Activation of proMMP8 See in Reactome R-HSA-1602458 ( R-HSA-1592389 ) R-HSA-1602458 Reaction Name: Activation of proMMP10 See in Reactome R-HSA-1602488 ( R-HSA-1592389 ) R-HSA-1602488 Reaction Name: Initial activation of proMMP13 by plasmin and trypsin See in Reactome R-HSA-1604712 ( R-HSA-1592389 ) R-HSA-1604712 Reaction Name: Initial activation of proMMP7 by trypsin See in Reactome R-HSA-1604722 ( R-HSA-1592389 ) R-HSA-1604722 Reaction Name: Activation of proMMP9 by proteases See in Reactome R-HSA-3132753 ( R-HSA-196741 ) R-HSA-3132753 Reaction Name: Pancreatic proteases degrade TCN1:RCbl See in Reactome
MONDO:0008185	CTRC	Q99895	3.4.21.2	R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism
MONDO:0009354	MTRR	Q9UBK8	1.16.1.8	R-HSA-1614635 R-HSA-1614635 Reactome Name: Sulfur amino acid metabolism See in Reactome R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome R-HSA-156581 R-HSA-156581 Reactome Name: Methylation See in Reactome	R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome	Metabolism	R-HSA-174374 ( R-HSA-156581; R-HSA-1614635; R-HSA-196741 ) R-HSA-174374 Reaction Name: MTR transfers CH3 from MeCbl to HCYS See in Reactome R-HSA-3149518 ( R-HSA-196741 ) R-HSA-3149518 Reaction Name: MTRR reduces cob(II)alamin to meCbl See in Reactome R-HSA-3149539 ( R-HSA-196741 ) R-HSA-3149539 Reaction Name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin See in Reactome R-HSA-3204318 ( R-HSA-196741 ) R-HSA-3204318 Reaction Name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR See in Reactome
MONDO:0009609	MTR	Q99707	2.1.1.13	R-HSA-9013407 R-HSA-9013407 Reactome Name: RHOH GTPase cycle See in Reactome R-HSA-1614635 R-HSA-1614635 Reactome Name: Sulfur amino acid metabolism See in Reactome R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome R-HSA-156581 R-HSA-156581 Reactome Name: Methylation See in Reactome	R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism Signal Transduction	R-HSA-174374 ( R-HSA-156581; R-HSA-1614635; R-HSA-196741 ) R-HSA-174374 Reaction Name: MTR transfers CH3 from MeCbl to HCYS See in Reactome R-HSA-3149518 ( R-HSA-196741 ) R-HSA-3149518 Reaction Name: MTRR reduces cob(II)alamin to meCbl See in Reactome R-HSA-3149539 ( R-HSA-196741 ) R-HSA-3149539 Reaction Name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin See in Reactome R-HSA-3204318 ( R-HSA-196741 ) R-HSA-3204318 Reaction Name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR See in Reactome R-HSA-9018758 ( R-HSA-9013407 ) R-HSA-9018758 Reaction Name: RHOH binds effectors at the plasma membrane See in Reactome
MONDO:0009612	MMACHC	Q9Y4U1	2.5.1.151 1.16.1.6	R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-3095889 ( R-HSA-196741 ) R-HSA-3095889 Reaction Name: MMACHC dealkylates RCbl See in Reactome R-HSA-3149494 ( R-HSA-196741 ) R-HSA-3149494 Reaction Name: MMACHC:cob(II)alamin binds MMADHC See in Reactome R-HSA-3149519 ( R-HSA-196741 ) R-HSA-3149519 Reaction Name: MMACHC decyanates CNCbl See in Reactome R-HSA-3149563 ( R-HSA-196741 ) R-HSA-3149563 Reaction Name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria See in Reactome R-HSA-3204318 ( R-HSA-196741 ) R-HSA-3204318 Reaction Name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR See in Reactome R-HSA-9759549 ( R-HSA-196741 ) R-HSA-9759549 Reaction Name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin See in Reactome
MONDO:0009613	MMAA	Q8IVH4	3.6.-.-	R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome R-HSA-71032 R-HSA-71032 Reactome Name: Propionyl-CoA catabolism See in Reactome	R-HSA-77289 R-HSA-77289 Reactome Name: Mitochondrial Fatty Acid Beta-Oxidation See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome	Metabolism	R-HSA-3159259 ( R-HSA-196741 ) R-HSA-3159259 Reaction Name: MMAA:MUT binds AdoCbl See in Reactome R-HSA-71010 ( R-HSA-71032 ) R-HSA-71010 Reaction Name: MUT isomerises L-MM-CoA to SUCC-CoA See in Reactome
MONDO:0009614	MMAB	Q96EY8	2.5.1.17	R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-3159253 ( R-HSA-196741 ) R-HSA-3159253 Reaction Name: MMAB adenosylates cob(I)alamin See in Reactome
MONDO:0010184	MMACHC	Q9Y4U1	2.5.1.151 1.16.1.6	R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-3095889 ( R-HSA-196741 ) R-HSA-3095889 Reaction Name: MMACHC dealkylates RCbl See in Reactome R-HSA-3149494 ( R-HSA-196741 ) R-HSA-3149494 Reaction Name: MMACHC:cob(II)alamin binds MMADHC See in Reactome R-HSA-3149519 ( R-HSA-196741 ) R-HSA-3149519 Reaction Name: MMACHC decyanates CNCbl See in Reactome R-HSA-3149563 ( R-HSA-196741 ) R-HSA-3149563 Reaction Name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria See in Reactome R-HSA-3204318 ( R-HSA-196741 ) R-HSA-3204318 Reaction Name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR See in Reactome R-HSA-9759549 ( R-HSA-196741 ) R-HSA-9759549 Reaction Name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin See in Reactome
MONDO:0011120	MTR	Q99707	2.1.1.13	R-HSA-9013407 R-HSA-9013407 Reactome Name: RHOH GTPase cycle See in Reactome R-HSA-1614635 R-HSA-1614635 Reactome Name: Sulfur amino acid metabolism See in Reactome R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome R-HSA-156581 R-HSA-156581 Reactome Name: Methylation See in Reactome	R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism Signal Transduction	R-HSA-174374 ( R-HSA-156581; R-HSA-1614635; R-HSA-196741 ) R-HSA-174374 Reaction Name: MTR transfers CH3 from MeCbl to HCYS See in Reactome R-HSA-3149518 ( R-HSA-196741 ) R-HSA-3149518 Reaction Name: MTRR reduces cob(II)alamin to meCbl See in Reactome R-HSA-3149539 ( R-HSA-196741 ) R-HSA-3149539 Reaction Name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin See in Reactome R-HSA-3204318 ( R-HSA-196741 ) R-HSA-3204318 Reaction Name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR See in Reactome R-HSA-9018758 ( R-HSA-9013407 ) R-HSA-9018758 Reaction Name: RHOH binds effectors at the plasma membrane See in Reactome
MONDO:0011120	MTRR	Q9UBK8	1.16.1.8	R-HSA-1614635 R-HSA-1614635 Reactome Name: Sulfur amino acid metabolism See in Reactome R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome R-HSA-156581 R-HSA-156581 Reactome Name: Methylation See in Reactome	R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome	Metabolism	R-HSA-174374 ( R-HSA-156581; R-HSA-1614635; R-HSA-196741 ) R-HSA-174374 Reaction Name: MTR transfers CH3 from MeCbl to HCYS See in Reactome R-HSA-3149518 ( R-HSA-196741 ) R-HSA-3149518 Reaction Name: MTRR reduces cob(II)alamin to meCbl See in Reactome R-HSA-3149539 ( R-HSA-196741 ) R-HSA-3149539 Reaction Name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin See in Reactome R-HSA-3204318 ( R-HSA-196741 ) R-HSA-3204318 Reaction Name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR See in Reactome
MONDO:0013543	PRSS1	P07477	3.4.21.4	R-HSA-1592389 R-HSA-1592389 Reactome Name: Activation of Matrix Metalloproteinases See in Reactome R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome	R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1474228 R-HSA-1474228 Reactome Name: Degradation of the extracellular matrix See in Reactome	Extracellular matrix organization Metabolism	R-HSA-1592316 ( R-HSA-1592389 ) R-HSA-1592316 Reaction Name: Initial activation of proMMP1 See in Reactome R-HSA-1592371 ( R-HSA-1592389 ) R-HSA-1592371 Reaction Name: Initial activation of proMMP3 See in Reactome R-HSA-1592398 ( R-HSA-1592389 ) R-HSA-1592398 Reaction Name: Activation of proMMP8 See in Reactome R-HSA-1602458 ( R-HSA-1592389 ) R-HSA-1602458 Reaction Name: Activation of proMMP10 See in Reactome R-HSA-1602488 ( R-HSA-1592389 ) R-HSA-1602488 Reaction Name: Initial activation of proMMP13 by plasmin and trypsin See in Reactome R-HSA-1604712 ( R-HSA-1592389 ) R-HSA-1604712 Reaction Name: Initial activation of proMMP7 by trypsin See in Reactome R-HSA-1604722 ( R-HSA-1592389 ) R-HSA-1604722 Reaction Name: Activation of proMMP9 by proteases See in Reactome R-HSA-3132753 ( R-HSA-196741 ) R-HSA-3132753 Reaction Name: Pancreatic proteases degrade TCN1:RCbl See in Reactome
MONDO:0013925	ABCD4	O14678	7.6.2.8	R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5223313 ( R-HSA-196741 ) R-HSA-5223313 Reaction Name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) See in Reactome R-HSA-9759206 ( R-HSA-196741 ) R-HSA-9759206 Reaction Name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol See in Reactome
MONDO:0017360	MMUT	P22033	5.4.99.2	R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome R-HSA-71032 R-HSA-71032 Reactome Name: Propionyl-CoA catabolism See in Reactome	R-HSA-77289 R-HSA-77289 Reactome Name: Mitochondrial Fatty Acid Beta-Oxidation See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome	Metabolism	R-HSA-3159259 ( R-HSA-196741 ) R-HSA-3159259 Reaction Name: MMAA:MUT binds AdoCbl See in Reactome R-HSA-71010 ( R-HSA-71032 ) R-HSA-71010 Reaction Name: MUT isomerises L-MM-CoA to SUCC-CoA See in Reactome
MONDO:0018989	PRSS1	P07477	3.4.21.4	R-HSA-1592389 R-HSA-1592389 Reactome Name: Activation of Matrix Metalloproteinases See in Reactome R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome	R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1474228 R-HSA-1474228 Reactome Name: Degradation of the extracellular matrix See in Reactome	Extracellular matrix organization Metabolism	R-HSA-1592316 ( R-HSA-1592389 ) R-HSA-1592316 Reaction Name: Initial activation of proMMP1 See in Reactome R-HSA-1592371 ( R-HSA-1592389 ) R-HSA-1592371 Reaction Name: Initial activation of proMMP3 See in Reactome R-HSA-1592398 ( R-HSA-1592389 ) R-HSA-1592398 Reaction Name: Activation of proMMP8 See in Reactome R-HSA-1602458 ( R-HSA-1592389 ) R-HSA-1602458 Reaction Name: Activation of proMMP10 See in Reactome R-HSA-1602488 ( R-HSA-1592389 ) R-HSA-1602488 Reaction Name: Initial activation of proMMP13 by plasmin and trypsin See in Reactome R-HSA-1604712 ( R-HSA-1592389 ) R-HSA-1604712 Reaction Name: Initial activation of proMMP7 by trypsin See in Reactome R-HSA-1604722 ( R-HSA-1592389 ) R-HSA-1604722 Reaction Name: Activation of proMMP9 by proteases See in Reactome R-HSA-3132753 ( R-HSA-196741 ) R-HSA-3132753 Reaction Name: Pancreatic proteases degrade TCN1:RCbl See in Reactome
MONDO:0019267	MMUT	P22033	5.4.99.2	R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome R-HSA-71032 R-HSA-71032 Reactome Name: Propionyl-CoA catabolism See in Reactome	R-HSA-77289 R-HSA-77289 Reactome Name: Mitochondrial Fatty Acid Beta-Oxidation See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome	Metabolism	R-HSA-3159259 ( R-HSA-196741 ) R-HSA-3159259 Reaction Name: MMAA:MUT binds AdoCbl See in Reactome R-HSA-71010 ( R-HSA-71032 ) R-HSA-71010 Reaction Name: MUT isomerises L-MM-CoA to SUCC-CoA See in Reactome
MONDO:0030058	ABCC1	P33527	7.6.2.2 7.6.2.3	R-HSA-2142691 R-HSA-2142691 Reactome Name: Synthesis of Leukotrienes (LT) and Eoxins (EX) See in Reactome R-HSA-9707564 R-HSA-9707564 Reactome Name: Cytoprotection by HMOX1 See in Reactome R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome R-HSA-189483 R-HSA-189483 Reactome Name: Heme degradation See in Reactome R-HSA-382556 R-HSA-382556 Reactome Name: ABC-family proteins mediated transport See in Reactome	R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-189445 R-HSA-189445 Reactome Name: Metabolism of porphyrins See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-9711123 R-HSA-9711123 Reactome Name: Cellular response to chemical stress See in Reactome	Cellular responses to stimuli Transport of small molecules Metabolism	R-HSA-1454916 ( R-HSA-382556 ) R-HSA-1454916 Reaction Name: The ABCC family mediates organic anion transport See in Reactome R-HSA-266070 ( R-HSA-2142691 ) R-HSA-266070 Reaction Name: LTC4 is exported from the cytosol by ABCC1 See in Reactome R-HSA-3095901 ( R-HSA-196741 ) R-HSA-3095901 Reaction Name: ABCC1 transports cytosolic RCbl to extracellular region See in Reactome R-HSA-9661405 ( R-HSA-189483; R-HSA-9707564 ) R-HSA-9661405 Reaction Name: ABCC1 transports BIL from cytosol to extracellular region (blood) See in Reactome