DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-196108)

Number of enzymes:	3
Number of disease:	6
Number of reactomes:	3
Number of reactions:	7

Search results (Reactome ID: R-HSA-196108)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013400	CYP11A1	P05108	1.14.15.6	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-196108 R-HSA-196108 Reactome Name: Pregnenolone biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193054 ( R-HSA-196108 ) R-HSA-193054 Reaction Name: Oxidation of cholesterol to 22beta-hydroxycholesterol See in Reactome R-HSA-193065 ( R-HSA-196108 ) R-HSA-193065 Reaction Name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol See in Reactome R-HSA-193101 ( R-HSA-196108; R-HSA-211976 ) R-HSA-193101 Reaction Name: CYP11A1 cleaves 20a,22b-DHCHOL See in Reactome
MONDO:0017337	CYP11A1	P05108	1.14.15.6	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-196108 R-HSA-196108 Reactome Name: Pregnenolone biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193054 ( R-HSA-196108 ) R-HSA-193054 Reaction Name: Oxidation of cholesterol to 22beta-hydroxycholesterol See in Reactome R-HSA-193065 ( R-HSA-196108 ) R-HSA-193065 Reaction Name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol See in Reactome R-HSA-193101 ( R-HSA-196108; R-HSA-211976 ) R-HSA-193101 Reaction Name: CYP11A1 cleaves 20a,22b-DHCHOL See in Reactome
MONDO:0017972	STAR	P49675	-	R-HSA-196108 R-HSA-196108 Reactome Name: Pregnenolone biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-196086 ( R-HSA-196108 ) R-HSA-196086 Reaction Name: Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane See in Reactome R-HSA-196126 ( R-HSA-196108 ) R-HSA-196126 Reaction Name: CHOL translocates from cytosol to mitochondrial intermembrane space See in Reactome
MONDO:0017973	STAR	P49675	-	R-HSA-196108 R-HSA-196108 Reactome Name: Pregnenolone biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-196086 ( R-HSA-196108 ) R-HSA-196086 Reaction Name: Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane See in Reactome R-HSA-196126 ( R-HSA-196108 ) R-HSA-196126 Reaction Name: CHOL translocates from cytosol to mitochondrial intermembrane space See in Reactome
MONDO:0034092	FDXR	P22570	1.18.1.6	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2395516 R-HSA-2395516 Reactome Name: Electron transport from NADPH to Ferredoxin See in Reactome R-HSA-196108 R-HSA-196108 Reactome Name: Pregnenolone biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1362409 R-HSA-1362409 Reactome Name: Mitochondrial iron-sulfur cluster biogenesis See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193054 ( R-HSA-196108 ) R-HSA-193054 Reaction Name: Oxidation of cholesterol to 22beta-hydroxycholesterol See in Reactome R-HSA-193065 ( R-HSA-196108 ) R-HSA-193065 Reaction Name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol See in Reactome R-HSA-193101 ( R-HSA-196108; R-HSA-211976 ) R-HSA-193101 Reaction Name: CYP11A1 cleaves 20a,22b-DHCHOL See in Reactome R-HSA-2395512 ( R-HSA-2395516 ) R-HSA-2395512 Reaction Name: FDXR transfers electrons to FDX1,2 (FDX1L) See in Reactome R-HSA-2395517 ( R-HSA-2395516 ) R-HSA-2395517 Reaction Name: NADPH transfers electrons to FDXR See in Reactome
MONDO:0060582	FDXR	P22570	1.18.1.6	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-2395516 R-HSA-2395516 Reactome Name: Electron transport from NADPH to Ferredoxin See in Reactome R-HSA-196108 R-HSA-196108 Reactome Name: Pregnenolone biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1362409 R-HSA-1362409 Reactome Name: Mitochondrial iron-sulfur cluster biogenesis See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193054 ( R-HSA-196108 ) R-HSA-193054 Reaction Name: Oxidation of cholesterol to 22beta-hydroxycholesterol See in Reactome R-HSA-193065 ( R-HSA-196108 ) R-HSA-193065 Reaction Name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol See in Reactome R-HSA-193101 ( R-HSA-196108; R-HSA-211976 ) R-HSA-193101 Reaction Name: CYP11A1 cleaves 20a,22b-DHCHOL See in Reactome R-HSA-2395512 ( R-HSA-2395516 ) R-HSA-2395512 Reaction Name: FDXR transfers electrons to FDX1,2 (FDX1L) See in Reactome R-HSA-2395517 ( R-HSA-2395516 ) R-HSA-2395517 Reaction Name: NADPH transfers electrons to FDXR See in Reactome