DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-193993)

Number of enzymes:	3
Number of disease:	6
Number of reactomes:	4
Number of reactions:	11

Search results (Reactome ID: R-HSA-193993)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007080	CYP11B2	P19099	1.14.15.5 1.14.15.4	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193965 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193965 Reaction Name: CYP11B2 oxidises 18HCORST to ALDO See in Reactome R-HSA-193995 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193995 Reaction Name: CYP11B2 18-hydroxylates CORST to 18HCORST See in Reactome R-HSA-193997 ( R-HSA-194002; R-HSA-211976 ) R-HSA-193997 Reaction Name: CYP11B1 oxidises 11DCORT See in Reactome R-HSA-194017 ( R-HSA-193993; R-HSA-211976 ) R-HSA-194017 Reaction Name: CYP11B2 oxidises 11DCORST to CORST See in Reactome
MONDO:0008727	HSD3B2	P26439	5.3.3.1 1.1.1.145	R-HSA-193048 R-HSA-193048 Reactome Name: Androgen biosynthesis See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193052 ( R-HSA-193993 ) R-HSA-193052 Reaction Name: Pregn-5-ene-3,20-dione isomerizes to progesterone See in Reactome R-HSA-193073 ( R-HSA-193048 ) R-HSA-193073 Reaction Name: HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST See in Reactome R-HSA-193961 ( R-HSA-194002 ) R-HSA-193961 Reaction Name: Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone See in Reactome R-HSA-196350 ( R-HSA-193993 ) R-HSA-196350 Reaction Name: Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione See in Reactome R-HSA-196372 ( R-HSA-194002 ) R-HSA-196372 Reaction Name: 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol See in Reactome
MONDO:0008751	CYP11B2	P19099	1.14.15.5 1.14.15.4	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193965 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193965 Reaction Name: CYP11B2 oxidises 18HCORST to ALDO See in Reactome R-HSA-193995 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193995 Reaction Name: CYP11B2 18-hydroxylates CORST to 18HCORST See in Reactome R-HSA-193997 ( R-HSA-194002; R-HSA-211976 ) R-HSA-193997 Reaction Name: CYP11B1 oxidises 11DCORT See in Reactome R-HSA-194017 ( R-HSA-193993; R-HSA-211976 ) R-HSA-194017 Reaction Name: CYP11B2 oxidises 11DCORST to CORST See in Reactome
MONDO:0012524	CYP11B2	P19099	1.14.15.5 1.14.15.4	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193965 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193965 Reaction Name: CYP11B2 oxidises 18HCORST to ALDO See in Reactome R-HSA-193995 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193995 Reaction Name: CYP11B2 18-hydroxylates CORST to 18HCORST See in Reactome R-HSA-193997 ( R-HSA-194002; R-HSA-211976 ) R-HSA-193997 Reaction Name: CYP11B1 oxidises 11DCORT See in Reactome R-HSA-194017 ( R-HSA-193993; R-HSA-211976 ) R-HSA-194017 Reaction Name: CYP11B2 oxidises 11DCORST to CORST See in Reactome
MONDO:0017839	CYP21A2	P08686	1.14.14.16	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193964 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193964 Reaction Name: CYP21A2 21-hydroxylates PROG See in Reactome R-HSA-193981 ( R-HSA-194002 ) R-HSA-193981 Reaction Name: CYP21A2 oxidises 17HPROG See in Reactome
MONDO:0017840	CYP21A2	P08686	1.14.14.16	R-HSA-211976 R-HSA-211976 Reactome Name: Endogenous sterols See in Reactome R-HSA-194002 R-HSA-194002 Reactome Name: Glucocorticoid biosynthesis See in Reactome R-HSA-193993 R-HSA-193993 Reactome Name: Mineralocorticoid biosynthesis See in Reactome	R-HSA-211897 R-HSA-211897 Reactome Name: Cytochrome P450 - arranged by substrate type See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-211945 R-HSA-211945 Reactome Name: Phase I - Functionalization of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-196071 R-HSA-196071 Reactome Name: Metabolism of steroid hormones See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-193964 ( R-HSA-193993; R-HSA-211976 ) R-HSA-193964 Reaction Name: CYP21A2 21-hydroxylates PROG See in Reactome R-HSA-193981 ( R-HSA-194002 ) R-HSA-193981 Reaction Name: CYP21A2 oxidises 17HPROG See in Reactome