DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-1483191)

Number of enzymes:	8
Number of disease:	11
Number of reactomes:	15
Number of reactions:	23

Search results (Reactome ID: R-HSA-1483191)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008807	CHAT	P28329	2.3.1.6	R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-264642 R-HSA-264642 Reactome Name: Acetylcholine Neurotransmitter Release Cycle See in Reactome	R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-112310 R-HSA-112310 Reactome Name: Neurotransmitter release cycle See in Reactome	Neuronal System Metabolism	R-HSA-264622 ( R-HSA-1483191; R-HSA-264642 ) R-HSA-264622 Reaction Name: Cho is acetylated to AcCho by CHAT See in Reactome
MONDO:0009689	CHAT	P28329	2.3.1.6	R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-264642 R-HSA-264642 Reactome Name: Acetylcholine Neurotransmitter Release Cycle See in Reactome	R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-112310 R-HSA-112310 Reactome Name: Neurotransmitter release cycle See in Reactome	Neuronal System Metabolism	R-HSA-264622 ( R-HSA-1483191; R-HSA-264642 ) R-HSA-264622 Reaction Name: Cho is acetylated to AcCho by CHAT See in Reactome
MONDO:0009992	LPIN1	Q14693	3.1.3.4	R-HSA-4419969 R-HSA-4419969 Reactome Name: Depolymerisation of the Nuclear Lamina See in Reactome R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-1483213 R-HSA-1483213 Reactome Name: Synthesis of PE See in Reactome R-HSA-75109 R-HSA-75109 Reactome Name: Triglyceride biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-2980766 R-HSA-2980766 Reactome Name: Nuclear Envelope Breakdown See in Reactome R-HSA-68875 R-HSA-68875 Reactome Name: Mitotic Prophase See in Reactome	Metabolism Cell Cycle	R-HSA-1483203 ( R-HSA-1483191; R-HSA-1483213 ) R-HSA-1483203 Reaction Name: PA is dephosphorylated to DAG by LPIN See in Reactome R-HSA-4419948 ( R-HSA-4419969 ) R-HSA-4419948 Reaction Name: CTDNEP1:CNEP1R1 dephosphorylates LPIN See in Reactome R-HSA-5195402 ( R-HSA-4419969 ) R-HSA-5195402 Reaction Name: CDK1 phosphorylates LPIN See in Reactome R-HSA-5221130 ( R-HSA-4419969 ) R-HSA-5221130 Reaction Name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol See in Reactome R-HSA-75899 ( R-HSA-75109 ) R-HSA-75899 Reaction Name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate See in Reactome
MONDO:0010923	CHKB	Q9Y259	2.7.1.32 2.7.1.82	R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-1483213 R-HSA-1483213 Reactome Name: Synthesis of PE See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome	Metabolism	R-HSA-1483004 ( R-HSA-1483191 ) R-HSA-1483004 Reaction Name: Cho is phosphorylated to PCho by CHK dimer See in Reactome R-HSA-1483222 ( R-HSA-1483213 ) R-HSA-1483222 Reaction Name: ETA is phosphorylated to PETA by CHK/ETNK See in Reactome
MONDO:0011246	CHKB	Q9Y259	2.7.1.32 2.7.1.82	R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-1483213 R-HSA-1483213 Reactome Name: Synthesis of PE See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome	Metabolism	R-HSA-1483004 ( R-HSA-1483191 ) R-HSA-1483004 Reaction Name: Cho is phosphorylated to PCho by CHK dimer See in Reactome R-HSA-1483222 ( R-HSA-1483213 ) R-HSA-1483222 Reaction Name: ETA is phosphorylated to PETA by CHK/ETNK See in Reactome
MONDO:0012160	PCYT1A	P49585	2.7.7.15	R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome	Metabolism	R-HSA-1483081 ( R-HSA-1483191 ) R-HSA-1483081 Reaction Name: PCho and CTP are condensed to CDP-Cho by PCYT1 dimer See in Reactome
MONDO:0012316	LPIN2	Q92539	3.1.3.4	R-HSA-4419969 R-HSA-4419969 Reactome Name: Depolymerisation of the Nuclear Lamina See in Reactome R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-1483213 R-HSA-1483213 Reactome Name: Synthesis of PE See in Reactome R-HSA-75109 R-HSA-75109 Reactome Name: Triglyceride biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-2980766 R-HSA-2980766 Reactome Name: Nuclear Envelope Breakdown See in Reactome R-HSA-68875 R-HSA-68875 Reactome Name: Mitotic Prophase See in Reactome	Metabolism Cell Cycle	R-HSA-1483203 ( R-HSA-1483191; R-HSA-1483213 ) R-HSA-1483203 Reaction Name: PA is dephosphorylated to DAG by LPIN See in Reactome R-HSA-4419948 ( R-HSA-4419969 ) R-HSA-4419948 Reaction Name: CTDNEP1:CNEP1R1 dephosphorylates LPIN See in Reactome R-HSA-5195402 ( R-HSA-4419969 ) R-HSA-5195402 Reaction Name: CDK1 phosphorylates LPIN See in Reactome R-HSA-5221130 ( R-HSA-4419969 ) R-HSA-5221130 Reaction Name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol See in Reactome R-HSA-75899 ( R-HSA-75109 ) R-HSA-75899 Reaction Name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate See in Reactome
MONDO:0014660	MFSD2A	Q8NA29	-	R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome	Metabolism	R-HSA-8865637 ( R-HSA-1483191 ) R-HSA-8865637 Reaction Name: MFSD2A transports LPC from extracellular region to plasma membrane See in Reactome
MONDO:0014893	CSNK2A1	P68400	2.7.11.1	R-HSA-445144 R-HSA-445144 Reactome Name: Signal transduction by L1 See in Reactome R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-6814122 R-HSA-6814122 Reactome Name: Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding See in Reactome R-HSA-8939243 R-HSA-8939243 Reactome Name: RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known See in Reactome R-HSA-6804756 R-HSA-6804756 Reactome Name: Regulation of TP53 Activity through Phosphorylation See in Reactome R-HSA-201688 R-HSA-201688 Reactome Name: WNT mediated activation of DVL See in Reactome R-HSA-2514853 R-HSA-2514853 Reactome Name: Condensation of Prometaphase Chromosomes See in Reactome R-HSA-8948751 R-HSA-8948751 Reactome Name: Regulation of PTEN stability and activity See in Reactome R-HSA-8934903 R-HSA-8934903 Reactome Name: Receptor Mediated Mitophagy See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-373760 R-HSA-373760 Reactome Name: L1CAM interactions See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-1257604 R-HSA-1257604 Reactome Name: PIP3 activates AKT signaling See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-390466 R-HSA-390466 Reactome Name: Chaperonin-mediated protein folding See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9612973 R-HSA-9612973 Reactome Name: Autophagy See in Reactome R-HSA-9663891 R-HSA-9663891 Reactome Name: Selective autophagy See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-5205647 R-HSA-5205647 Reactome Name: Mitophagy See in Reactome R-HSA-1632852 R-HSA-1632852 Reactome Name: Macroautophagy See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-391251 R-HSA-391251 Reactome Name: Protein folding See in Reactome R-HSA-6807070 R-HSA-6807070 Reactome Name: PTEN Regulation See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-68877 R-HSA-68877 Reactome Name: Mitotic Prometaphase See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism Cell Cycle Developmental Biology Gene expression (Transcription) Autophagy Metabolism of proteins Signal Transduction	R-HSA-201717 ( R-HSA-201688 ) R-HSA-201717 Reaction Name: CSNK2-mediated phosphorylation of DVL See in Reactome R-HSA-2529020 ( R-HSA-2514853 ) R-HSA-2529020 Reaction Name: CK2 phosphorylates condensin I subunits See in Reactome R-HSA-392752 ( R-HSA-445144 ) R-HSA-392752 Reaction Name: Phosphorylation of L1 by CK-II See in Reactome R-HSA-6805059 ( R-HSA-6804756 ) R-HSA-6805059 Reaction Name: CK2:FACT phosphorylates TP53 See in Reactome R-HSA-6805061 ( R-HSA-6804756 ) R-HSA-6805061 Reaction Name: CK2 binds FACT See in Reactome R-HSA-6814409 ( R-HSA-6814122 ) R-HSA-6814409 Reaction Name: CK2 phosphorylates PDCL See in Reactome R-HSA-8850945 ( R-HSA-8948751 ) R-HSA-8850945 Reaction Name: Casein kinase II phosphorylates PTEN See in Reactome R-HSA-8873929 ( R-HSA-1483191 ) R-HSA-8873929 Reaction Name: Casein kinase II phosphorylates STARD10 See in Reactome R-HSA-8932322 () R-HSA-8932322 Reaction Name: CK2 phosphorylates NFE2L2 See in Reactome R-HSA-8937989 ( R-HSA-8939243 ) R-HSA-8937989 Reaction Name: RUNX1 binds PRC1 complexes See in Reactome R-HSA-8948039 ( R-HSA-8934903 ) R-HSA-8948039 Reaction Name: FUNDC1 is phosphorylated by CK2 See in Reactome
MONDO:0015270	BCHE	P06276	3.1.1.8	R-HSA-422085 R-HSA-422085 Reactome Name: Synthesis, secretion, and deacylation of Ghrelin See in Reactome R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome R-HSA-112311 R-HSA-112311 Reactome Name: Neurotransmitter clearance See in Reactome	R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-2980736 R-HSA-2980736 Reactome Name: Peptide hormone metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome	Metabolism of proteins Neuronal System Metabolism	R-HSA-372519 ( R-HSA-112311; R-HSA-1483191 ) R-HSA-372519 Reaction Name: AcCho is hydrolyzed to Cho and acetate by ACHE See in Reactome R-HSA-9023617 ( R-HSA-422085 ) R-HSA-9023617 Reaction Name: Butyrylcholinesterase hydrolyzes acyl Ghrelin See in Reactome
MONDO:0018998	PCYT1A	P49585	2.7.7.15	R-HSA-1483191 R-HSA-1483191 Reactome Name: Synthesis of PC See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome	Metabolism	R-HSA-1483081 ( R-HSA-1483191 ) R-HSA-1483081 Reaction Name: PCho and CTP are condensed to CDP-Cho by PCYT1 dimer See in Reactome