DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-1482883)

Number of enzymes:	4
Number of disease:	4
Number of reactomes:	5
Number of reactions:	9

Search results (Reactome ID: R-HSA-1482883)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0012545	PNPLA2	Q96AD5	3.1.1.3	R-HSA-381426 R-HSA-381426 Reactome Name: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) See in Reactome R-HSA-1482883 R-HSA-1482883 Reactome Name: Acyl chain remodeling of DAG and TAG See in Reactome R-HSA-8957275 R-HSA-8957275 Reactome Name: Post-translational protein phosphorylation See in Reactome	R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins Metabolism	R-HSA-1482647 ( R-HSA-1482883 ) R-HSA-1482647 Reaction Name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 See in Reactome R-HSA-1482654 ( R-HSA-1482883 ) R-HSA-1482654 Reaction Name: 2-MAG is transacylated to DAG by PNPLA2/3 See in Reactome R-HSA-1482777 ( R-HSA-1482883 ) R-HSA-1482777 Reaction Name: TAG is hydrolyzed to DAG by PNPLA2/3 See in Reactome R-HSA-1482811 ( R-HSA-1482883 ) R-HSA-1482811 Reaction Name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 See in Reactome R-HSA-8952289 ( R-HSA-381426; R-HSA-8957275 ) R-HSA-8952289 Reaction Name: FAM20C phosphorylates FAM20C substrates See in Reactome
MONDO:0014375	DGAT1	O75907	2.3.1.20 2.3.1.76	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-1482883 R-HSA-1482883 Reactome Name: Acyl chain remodeling of DAG and TAG See in Reactome R-HSA-75109 R-HSA-75109 Reactome Name: Triglyceride biosynthesis See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome	Immune System Metabolism	R-HSA-1482889 ( R-HSA-1482883 ) R-HSA-1482889 Reaction Name: DAG is acylated to TAG by DGAT1/2 See in Reactome R-HSA-6799350 ( R-HSA-6798695 ) R-HSA-6799350 Reaction Name: Exocytosis of specific granule membrane proteins See in Reactome R-HSA-75900 ( R-HSA-75109 ) R-HSA-75900 Reaction Name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] See in Reactome
MONDO:0021105	PNPLA3	Q9NST1	2.3.1.51 3.1.1.3	R-HSA-1482883 R-HSA-1482883 Reactome Name: Acyl chain remodeling of DAG and TAG See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome	Metabolism	R-HSA-1482647 ( R-HSA-1482883 ) R-HSA-1482647 Reaction Name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 See in Reactome R-HSA-1482654 ( R-HSA-1482883 ) R-HSA-1482654 Reaction Name: 2-MAG is transacylated to DAG by PNPLA2/3 See in Reactome R-HSA-1482777 ( R-HSA-1482883 ) R-HSA-1482777 Reaction Name: TAG is hydrolyzed to DAG by PNPLA2/3 See in Reactome R-HSA-1482811 ( R-HSA-1482883 ) R-HSA-1482811 Reaction Name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 See in Reactome
MONDO:0044625	DGAT2	Q96PD7	2.3.1.20 2.3.1.76	R-HSA-1482883 R-HSA-1482883 Reactome Name: Acyl chain remodeling of DAG and TAG See in Reactome R-HSA-75109 R-HSA-75109 Reactome Name: Triglyceride biosynthesis See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome	Metabolism	R-HSA-1482889 ( R-HSA-1482883 ) R-HSA-1482889 Reaction Name: DAG is acylated to TAG by DGAT1/2 See in Reactome R-HSA-549192 ( R-HSA-75109 ) R-HSA-549192 Reaction Name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] See in Reactome