DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-1368108)

Number of enzymes:	2
Number of disease:	3
Number of reactomes:	37
Number of reactions:	137

Search results (Reactome ID: R-HSA-1368108)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008393	CREBBP	Q92793	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-8939246 R-HSA-8939246 Reactome Name: RUNX1 regulates transcription of genes involved in differentiation of myeloid cells See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2151201 R-HSA-2151201 Reactome Name: Transcriptional activation of mitochondrial biogenesis See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-350054 R-HSA-350054 Reactome Name: Notch-HLH transcription pathway See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-6803204 R-HSA-6803204 Reactome Name: TP53 Regulates Transcription of Genes Involved in Cytochrome C Release See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-1368108 R-HSA-1368108 Reactome Name: BMAL1:CLOCK,NPAS2 activates circadian gene expression See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9707564 R-HSA-9707564 Reactome Name: Cytoprotection by HMOX1 See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-1592230 R-HSA-1592230 Reactome Name: Mitochondrial biogenesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5633008 R-HSA-5633008 Reactome Name: TP53 Regulates Transcription of Cell Death Genes See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-1852241 R-HSA-1852241 Reactome Name: Organelle biogenesis and maintenance See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-9711123 R-HSA-9711123 Reactome Name: Cellular response to chemical stress See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome	Circadian Clock Immune System Metabolism Developmental Biology Gene expression (Transcription) Organelle biogenesis and maintenance Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-1989746 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989746 Reaction Name: Expression of CYP7A1 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-1989756 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989756 Reaction Name: Expression of ME1 See in Reactome R-HSA-1989754 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989754 Reaction Name: Expression of APOA1 See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-1989755 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989755 Reaction Name: Expression of CYP4A11 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-1989753 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989753 Reaction Name: Expression of PEX11A See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-8938231 ( R-HSA-8939246 ) R-HSA-8938231 Reaction Name: RUNX1:CBFB binds CREBBP See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-400143 ( R-HSA-400206; R-HSA-9707564 ) R-HSA-400143 Reaction Name: Fatty acid ligands activate PPARA See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-1592238 ( R-HSA-1989781; R-HSA-2151201; R-HSA-400206 ) R-HSA-1592238 Reaction Name: Expression of ALAS1 See in Reactome R-HSA-1989751 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989751 Reaction Name: Expression of FABP1 See in Reactome R-HSA-1989777 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989777 Reaction Name: Expression of RGL1 See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-1989745 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989745 Reaction Name: Expression of ACADM See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-1989772 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989772 Reaction Name: Expression of GLIPR1 See in Reactome R-HSA-1989771 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989771 Reaction Name: Expression of TNFRSF21 See in Reactome R-HSA-1655850 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655850 Reaction Name: Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) See in Reactome R-HSA-3927959 ( R-HSA-3899300 ) R-HSA-3927959 Reaction Name: SUMOylation of CREBBP with SUMO1 See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400206; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-212356 ( R-HSA-350054 ) R-HSA-212356 Reaction Name: Formation of CSL-NICD coactivator complex See in Reactome R-HSA-879724 ( R-HSA-1368108; R-HSA-1989781; R-HSA-400206; R-HSA-400253 ) R-HSA-879724 Reaction Name: Expression of PPARA See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-9626945 ( R-HSA-9617629 ) R-HSA-9626945 Reaction Name: CREBBP acetylates FOXO1 See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-6798004 ( R-HSA-6803204 ) R-HSA-6798004 Reaction Name: TP53 stimulates BNIP3L expression See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-1989773 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989773 Reaction Name: Expression of CPT2 See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-8938228 ( R-HSA-8939246 ) R-HSA-8938228 Reaction Name: RUNX1:CBFB:CREBBP binds the CSF2 (GM-CSF) gene promoter See in Reactome R-HSA-1989765 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989765 Reaction Name: Expression of ABCA1 See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-1989764 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989764 Reaction Name: Expression of CYP1A1 See in Reactome R-HSA-1989758 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989758 Reaction Name: Expression of UGT1A9 See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1989750 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989750 Reaction Name: Expression of FATP1 (SLC27A1) See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-1989775 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989775 Reaction Name: Expression of SULT2A1 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-1989747 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989747 Reaction Name: Expression of FHL2 See in Reactome R-HSA-1989776 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989776 Reaction Name: Expression of APOA2 See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-3697008 ( R-HSA-3214847 ) R-HSA-3697008 Reaction Name: CREBBP acetylates histone H2B, H3, H4 See in Reactome R-HSA-1989760 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989760 Reaction Name: Expression of HMGCS2 See in Reactome R-HSA-1989770 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989770 Reaction Name: Expression of PLIN2 See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-1989762 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989762 Reaction Name: Expression of ABCB4 See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-9626928 ( R-HSA-9617629 ) R-HSA-9626928 Reaction Name: CREBBP binds FOXO1 See in Reactome R-HSA-1989757 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989757 Reaction Name: Expression of FADS1 See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400206; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-1989778 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989778 Reaction Name: Expression of ACSL1 See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-1989767 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989767 Reaction Name: Expression of TRIB3 See in Reactome R-HSA-8938251 ( R-HSA-8939246 ) R-HSA-8938251 Reaction Name: CSF2 (GM-CSF) gene expression is stimulated by RUNX1 and CREBBP See in Reactome R-HSA-1989748 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989748 Reaction Name: Expression of GRHL1 See in Reactome R-HSA-4395227 ( R-HSA-1912408 ) R-HSA-4395227 Reaction Name: CCND1:CREBBP binds NOTCH1 promoter See in Reactome R-HSA-1989779 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989779 Reaction Name: Expression of ANKRD1 See in Reactome R-HSA-1989759 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989759 Reaction Name: Expression of G0S2 See in Reactome R-HSA-1655848 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655848 Reaction Name: Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-1989752 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989752 Reaction Name: Expression of TXNRD1 See in Reactome R-HSA-1989749 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989749 Reaction Name: Expression of ACOX1 See in Reactome R-HSA-1989761 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989761 Reaction Name: Expression of APOA5 See in Reactome R-HSA-1989768 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989768 Reaction Name: Expression of TIAM2 See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-1655826 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655826 Reaction Name: Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) See in Reactome R-HSA-1989774 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989774 Reaction Name: Expression of AGT See in Reactome R-HSA-6797993 ( R-HSA-6803204 ) R-HSA-6797993 Reaction Name: TP53 and CREBBP bind BNIP3L gene See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome
MONDO:0009211	F7	P08709	3.4.21.21	R-HSA-159740 R-HSA-159740 Reactome Name: Gamma-carboxylation of protein precursors See in Reactome R-HSA-140834 R-HSA-140834 Reactome Name: Extrinsic Pathway of Fibrin Clot Formation See in Reactome R-HSA-1368108 R-HSA-1368108 Reactome Name: BMAL1:CLOCK,NPAS2 activates circadian gene expression See in Reactome R-HSA-159763 R-HSA-159763 Reactome Name: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus See in Reactome R-HSA-159782 R-HSA-159782 Reactome Name: Removal of aminoterminal propeptides from gamma-carboxylated proteins See in Reactome	R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-163841 R-HSA-163841 Reactome Name: Gamma carboxylation, hypusine formation and arylsulfatase activation See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-159854 R-HSA-159854 Reactome Name: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-140877 R-HSA-140877 Reactome Name: Formation of Fibrin Clot (Clotting Cascade) See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome	Circadian Clock Metabolism of proteins Hemostasis	R-HSA-140736 ( R-HSA-140834 ) R-HSA-140736 Reaction Name: factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) See in Reactome R-HSA-140748 ( R-HSA-140834 ) R-HSA-140748 Reaction Name: tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex See in Reactome R-HSA-140769 ( R-HSA-140834 ) R-HSA-140769 Reaction Name: factor VII -> factor VIIa See in Reactome R-HSA-140777 ( R-HSA-140834 ) R-HSA-140777 Reaction Name: factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) See in Reactome R-HSA-140783 ( R-HSA-140834 ) R-HSA-140783 Reaction Name: tissue factor (TF) + factor VII (F7) -> TF:F7 complex See in Reactome R-HSA-140823 ( R-HSA-140834 ) R-HSA-140823 Reaction Name: factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) See in Reactome R-HSA-140825 ( R-HSA-140834 ) R-HSA-140825 Reaction Name: TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa See in Reactome R-HSA-159761 ( R-HSA-159740 ) R-HSA-159761 Reaction Name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) See in Reactome R-HSA-159783 ( R-HSA-159763 ) R-HSA-159783 Reaction Name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus See in Reactome R-HSA-159868 ( R-HSA-159782 ) R-HSA-159868 Reaction Name: Furin cleaves pro-factor VII to factor VII See in Reactome R-HSA-549428 ( R-HSA-1368108 ) R-HSA-549428 Reaction Name: Expression of FACTOR VII (F7) See in Reactome
MONDO:0020763	CREBBP	Q92793	2.3.1.- 2.3.1.48	R-HSA-9617629 R-HSA-9617629 Reactome Name: Regulation of FOXO transcriptional activity by acetylation See in Reactome R-HSA-210744 R-HSA-210744 Reactome Name: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome R-HSA-8939246 R-HSA-8939246 Reactome Name: RUNX1 regulates transcription of genes involved in differentiation of myeloid cells See in Reactome R-HSA-9013695 R-HSA-9013695 Reactome Name: NOTCH4 Intracellular Domain Regulates Transcription See in Reactome R-HSA-2151201 R-HSA-2151201 Reactome Name: Transcriptional activation of mitochondrial biogenesis See in Reactome R-HSA-8941856 R-HSA-8941856 Reactome Name: RUNX3 regulates NOTCH signaling See in Reactome R-HSA-350054 R-HSA-350054 Reactome Name: Notch-HLH transcription pathway See in Reactome R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9018519 R-HSA-9018519 Reactome Name: Estrogen-dependent gene expression See in Reactome R-HSA-918233 R-HSA-918233 Reactome Name: TRAF3-dependent IRF activation pathway See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome R-HSA-9013508 R-HSA-9013508 Reactome Name: NOTCH3 Intracellular Domain Regulates Transcription See in Reactome R-HSA-3214847 R-HSA-3214847 Reactome Name: HATs acetylate histones See in Reactome R-HSA-3371568 R-HSA-3371568 Reactome Name: Attenuation phase See in Reactome R-HSA-8866907 R-HSA-8866907 Reactome Name: Activation of the TFAP2 (AP-2) family of transcription factors See in Reactome R-HSA-6803204 R-HSA-6803204 Reactome Name: TP53 Regulates Transcription of Genes Involved in Cytochrome C Release See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome R-HSA-933541 R-HSA-933541 Reactome Name: TRAF6 mediated IRF7 activation See in Reactome R-HSA-1234158 R-HSA-1234158 Reactome Name: Regulation of gene expression by Hypoxia-inducible Factor See in Reactome R-HSA-1368082 R-HSA-1368082 Reactome Name: RORA activates gene expression See in Reactome R-HSA-5617472 R-HSA-5617472 Reactome Name: Activation of anterior HOX genes in hindbrain development during early embryogenesis See in Reactome R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-2122947 R-HSA-2122947 Reactome Name: NOTCH1 Intracellular Domain Regulates Transcription See in Reactome R-HSA-1368108 R-HSA-1368108 Reactome Name: BMAL1:CLOCK,NPAS2 activates circadian gene expression See in Reactome R-HSA-400253 R-HSA-400253 Reactome Name: Circadian Clock See in Reactome R-HSA-9707616 R-HSA-9707616 Reactome Name: Heme signaling See in Reactome R-HSA-3134973 R-HSA-3134973 Reactome Name: LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production See in Reactome R-HSA-201722 R-HSA-201722 Reactome Name: Formation of the beta-catenin:TCF transactivating complex See in Reactome R-HSA-1912408 R-HSA-1912408 Reactome Name: Pre-NOTCH Transcription and Translation See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome R-HSA-9707564 R-HSA-9707564 Reactome Name: Cytoprotection by HMOX1 See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-9012852 R-HSA-9012852 Reactome Name: Signaling by NOTCH3 See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-157118 R-HSA-157118 Reactome Name: Signaling by NOTCH See in Reactome R-HSA-1592230 R-HSA-1592230 Reactome Name: Mitochondrial biogenesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-5633008 R-HSA-5633008 Reactome Name: TP53 Regulates Transcription of Cell Death Genes See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-1852241 R-HSA-1852241 Reactome Name: Organelle biogenesis and maintenance See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-5619507 R-HSA-5619507 Reactome Name: Activation of HOX genes during differentiation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-1234174 R-HSA-1234174 Reactome Name: Cellular response to hypoxia See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-8939211 R-HSA-8939211 Reactome Name: ESR-mediated signaling See in Reactome R-HSA-9711123 R-HSA-9711123 Reactome Name: Cellular response to chemical stress See in Reactome R-HSA-1912422 R-HSA-1912422 Reactome Name: Pre-NOTCH Expression and Processing See in Reactome R-HSA-9013694 R-HSA-9013694 Reactome Name: Signaling by NOTCH4 See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-1980143 R-HSA-1980143 Reactome Name: Signaling by NOTCH1 See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-3371556 R-HSA-3371556 Reactome Name: Cellular response to heat stress See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-3371571 R-HSA-3371571 Reactome Name: HSF1-dependent transactivation See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-8878159 R-HSA-8878159 Reactome Name: Transcriptional regulation by RUNX3 See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome	Circadian Clock Immune System Metabolism Developmental Biology Gene expression (Transcription) Organelle biogenesis and maintenance Cellular responses to stimuli Metabolism of proteins Chromatin organization Signal Transduction	R-HSA-1989746 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989746 Reaction Name: Expression of CYP7A1 See in Reactome R-HSA-9761836 () R-HSA-9761836 Reaction Name: p14ARF binds NFE2L2:CREBBP, EP300 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-1989756 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989756 Reaction Name: Expression of ME1 See in Reactome R-HSA-1989754 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989754 Reaction Name: Expression of APOA1 See in Reactome R-HSA-4396371 ( R-HSA-2122947 ) R-HSA-4396371 Reaction Name: NOTCH1 Coactivator Complex binds MYC promoter See in Reactome R-HSA-9038052 ( R-HSA-9018519 ) R-HSA-9038052 Reaction Name: GREB1 binds ESR1:ESTG and co-activators See in Reactome R-HSA-1234167 ( R-HSA-1234158 ) R-HSA-1234167 Reaction Name: Formation of HIF:CBP:p300 complex at promoters See in Reactome R-HSA-9617758 ( R-HSA-9617629 ) R-HSA-9617758 Reaction Name: EP300,CREBBP acetylate FOXO4 See in Reactome R-HSA-9016751 ( R-HSA-9013508 ) R-HSA-9016751 Reaction Name: FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-1980065 ( R-HSA-2122947 ) R-HSA-1980065 Reaction Name: NOTCH1 stimulates HEY transcription See in Reactome R-HSA-9759332 () R-HSA-9759332 Reaction Name: AcK-NFE2L2 binds the TXNRD1 promoter See in Reactome R-HSA-1989755 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989755 Reaction Name: Expression of CYP4A11 See in Reactome R-HSA-1980067 ( R-HSA-2122947 ) R-HSA-1980067 Reaction Name: NOTCH1 stimulates MYC transcription See in Reactome R-HSA-9761849 () R-HSA-9761849 Reaction Name: AcK-NFE2L2-dependent P6GD gene expression See in Reactome R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-3134883 ( R-HSA-3134973 ) R-HSA-3134883 Reaction Name: Beta-catenin enhances association of IRF3 with CBP/p300 See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-1028820 ( R-HSA-933541 ) R-HSA-1028820 Reaction Name: Formation of VAF (virus-activated factor) complex See in Reactome R-HSA-8878243 ( R-HSA-8941856 ) R-HSA-8878243 Reaction Name: HES1 gene transcription is inhibited by RUNX3 See in Reactome R-HSA-1989753 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989753 Reaction Name: Expression of PEX11A See in Reactome R-HSA-9021450 ( R-HSA-9013508 ) R-HSA-9021450 Reaction Name: PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes See in Reactome R-HSA-9761828 () R-HSA-9761828 Reaction Name: NFE2L2 binds the PGD gene See in Reactome R-HSA-8938231 ( R-HSA-8939246 ) R-HSA-8938231 Reaction Name: RUNX1:CBFB binds CREBBP See in Reactome R-HSA-1028817 ( R-HSA-918233 ) R-HSA-1028817 Reaction Name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 See in Reactome R-HSA-400143 ( R-HSA-400206; R-HSA-9707564 ) R-HSA-400143 Reaction Name: Fatty acid ligands activate PPARA See in Reactome R-HSA-9761846 () R-HSA-9761846 Reaction Name: NFE2L2-dependent PGD gene expression See in Reactome R-HSA-4396347 ( R-HSA-2122947; R-HSA-8941856 ) R-HSA-4396347 Reaction Name: NOTCH1 Coactivator Complex binds HES1 promoter See in Reactome R-HSA-9759141 () R-HSA-9759141 Reaction Name: AcK-NFE2L2 and MAFK bind NQO1 gene See in Reactome R-HSA-9760125 () R-HSA-9760125 Reaction Name: AcK-NFE2L2-dependent GCLM gene expression See in Reactome R-HSA-1592238 ( R-HSA-1989781; R-HSA-2151201; R-HSA-400206 ) R-HSA-1592238 Reaction Name: Expression of ALAS1 See in Reactome R-HSA-1989751 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989751 Reaction Name: Expression of FABP1 See in Reactome R-HSA-1989777 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989777 Reaction Name: Expression of RGL1 See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-9622604 ( R-HSA-9614657 ) R-HSA-9622604 Reaction Name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y See in Reactome R-HSA-3371554 ( R-HSA-3371568 ) R-HSA-3371554 Reaction Name: HSF1 acetylation at Lys80 See in Reactome R-HSA-1989745 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989745 Reaction Name: Expression of ACADM See in Reactome R-HSA-9017835 ( R-HSA-1912408 ) R-HSA-9017835 Reaction Name: NOTCH1 coactivator complex binds NOTCH3 gene See in Reactome R-HSA-1989772 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989772 Reaction Name: Expression of GLIPR1 See in Reactome R-HSA-1989771 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989771 Reaction Name: Expression of TNFRSF21 See in Reactome R-HSA-1655850 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655850 Reaction Name: Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) See in Reactome R-HSA-3927959 ( R-HSA-3899300 ) R-HSA-3927959 Reaction Name: SUMOylation of CREBBP with SUMO1 See in Reactome R-HSA-1801587 ( R-HSA-1368082; R-HSA-1989781; R-HSA-400206; R-HSA-400253 ) R-HSA-1801587 Reaction Name: Expression of CPT1A See in Reactome R-HSA-9761812 () R-HSA-9761812 Reaction Name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD See in Reactome R-HSA-4396382 ( R-HSA-2122947 ) R-HSA-4396382 Reaction Name: NOTCH1 Coactivator Complex binds promoters of HEY genes See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-9760097 () R-HSA-9760097 Reaction Name: AcK-NFE2L2 and MAFK bind the GSTA1 gene See in Reactome R-HSA-212356 ( R-HSA-350054 ) R-HSA-212356 Reaction Name: Formation of CSL-NICD coactivator complex See in Reactome R-HSA-879724 ( R-HSA-1368108; R-HSA-1989781; R-HSA-400206; R-HSA-400253 ) R-HSA-879724 Reaction Name: Expression of PPARA See in Reactome R-HSA-1980047 ( R-HSA-210744; R-HSA-2122947; R-HSA-8941856 ) R-HSA-1980047 Reaction Name: NOTCH1 stimulates HES1 transcription See in Reactome R-HSA-9626945 ( R-HSA-9617629 ) R-HSA-9626945 Reaction Name: CREBBP acetylates FOXO1 See in Reactome R-HSA-1235037 ( R-HSA-1234158 ) R-HSA-1235037 Reaction Name: Expression of VEGFA See in Reactome R-HSA-8878237 ( R-HSA-8941856 ) R-HSA-8878237 Reaction Name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter See in Reactome R-HSA-9622579 ( R-HSA-9614657 ) R-HSA-9622579 Reaction Name: FOXO1,FOXO3,(FOXO4) bind BCL2L11 gene promoter See in Reactome R-HSA-933536 ( R-HSA-933541 ) R-HSA-933536 Reaction Name: p-IRF7 dimer interacts with coactivator CBP/p300 See in Reactome R-HSA-6798004 ( R-HSA-6803204 ) R-HSA-6798004 Reaction Name: TP53 stimulates BNIP3L expression See in Reactome R-HSA-9760128 () R-HSA-9760128 Reaction Name: AcK-NFE2L2-dependent GSTA1 gene expression See in Reactome R-HSA-9617683 ( R-HSA-9617629 ) R-HSA-9617683 Reaction Name: EP300,CREBBP bind SOH-C481-FOXO4 See in Reactome R-HSA-1912415 ( R-HSA-1912408 ) R-HSA-1912415 Reaction Name: NOTCH3 gene transcription See in Reactome R-HSA-1028812 ( R-HSA-918233 ) R-HSA-1028812 Reaction Name: Expression of interferon-beta See in Reactome R-HSA-1989773 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989773 Reaction Name: Expression of CPT2 See in Reactome R-HSA-9760082 () R-HSA-9760082 Reaction Name: NFE2L2 binds CREBBP,EP300 See in Reactome R-HSA-1912394 ( R-HSA-2122947 ) R-HSA-1912394 Reaction Name: NICD1 in complex with RBPJ (CSL) recruits MAML See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-8938228 ( R-HSA-8939246 ) R-HSA-8938228 Reaction Name: RUNX1:CBFB:CREBBP binds the CSF2 (GM-CSF) gene promoter See in Reactome R-HSA-1989765 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989765 Reaction Name: Expression of ABCA1 See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340; R-HSA-400206 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-1912393 Reaction Name: MAML in complex with NICD1 recruits CDK8 See in Reactome R-HSA-1989764 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989764 Reaction Name: Expression of CYP1A1 See in Reactome R-HSA-1989758 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989758 Reaction Name: Expression of UGT1A9 See in Reactome R-HSA-1028819 ( R-HSA-933541 ) R-HSA-1028819 Reaction Name: VAF/pIRF7:CBP/p300 binds the promoters of type-I IFN genes See in Reactome R-HSA-5660666 ( R-HSA-5621575 ) R-HSA-5660666 Reaction Name: CBP and p300 binds NF-kB complex See in Reactome R-HSA-1912416 ( R-HSA-1912408 ) R-HSA-1912416 Reaction Name: NOTCH1 gene transcription See in Reactome R-HSA-1989750 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989750 Reaction Name: Expression of FATP1 (SLC27A1) See in Reactome R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912391 Reaction Name: NICD1 is phosphorylated by CDK8 See in Reactome R-HSA-9761815 () R-HSA-9761815 Reaction Name: AcK-NFE2L2 and ATF4 bind the SLC7A11 gene See in Reactome R-HSA-9760122 () R-HSA-9760122 Reaction Name: AcK-NFE2L2-dependent GCLC gene expression See in Reactome R-HSA-1989775 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989775 Reaction Name: Expression of SULT2A1 See in Reactome R-HSA-1235035 ( R-HSA-1234158 ) R-HSA-1235035 Reaction Name: Expression of Carbonic Anhydrase IX (CA9) See in Reactome R-HSA-9021451 ( R-HSA-9013508 ) R-HSA-9021451 Reaction Name: NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter See in Reactome R-HSA-1989747 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989747 Reaction Name: Expression of FHL2 See in Reactome R-HSA-1989776 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989776 Reaction Name: Expression of APOA2 See in Reactome R-HSA-8864307 ( R-HSA-8866907 ) R-HSA-8864307 Reaction Name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP See in Reactome R-HSA-1028815 ( R-HSA-918233 ) R-HSA-1028815 Reaction Name: p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 binds promoters of Interferon-beta See in Reactome R-HSA-3697008 ( R-HSA-3214847 ) R-HSA-3697008 Reaction Name: CREBBP acetylates histone H2B, H3, H4 See in Reactome R-HSA-1989760 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989760 Reaction Name: Expression of HMGCS2 See in Reactome R-HSA-1989770 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989770 Reaction Name: Expression of PLIN2 See in Reactome R-HSA-8878220 ( R-HSA-8941856 ) R-HSA-8878220 Reaction Name: RUNX3 binds the NOTCH1 coactivator complex See in Reactome R-HSA-1989762 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989762 Reaction Name: Expression of ABCB4 See in Reactome R-HSA-1980078 ( R-HSA-2122947 ) R-HSA-1980078 Reaction Name: NOTCH1 stimulates HES5 transcription See in Reactome R-HSA-4396379 ( R-HSA-2122947 ) R-HSA-4396379 Reaction Name: NOTCH1 Coactivator Complex binds HES5 promoter See in Reactome R-HSA-9626928 ( R-HSA-9617629 ) R-HSA-9626928 Reaction Name: CREBBP binds FOXO1 See in Reactome R-HSA-1989757 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989757 Reaction Name: Expression of FADS1 See in Reactome R-HSA-1368065 ( R-HSA-1989781; R-HSA-400206; R-HSA-400253; R-HSA-9707616 ) R-HSA-1368065 Reaction Name: Expression of NPAS2 See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-9622572 ( R-HSA-9614657 ) R-HSA-9622572 Reaction Name: NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter See in Reactome R-HSA-9761841 () R-HSA-9761841 Reaction Name: AcK-NFE2L2-dependent SLC7A11 expression See in Reactome R-HSA-1989778 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989778 Reaction Name: Expression of ACSL1 See in Reactome R-HSA-5617874 ( R-HSA-5617472 ) R-HSA-5617874 Reaction Name: HOXD4 gene is transcribed See in Reactome R-HSA-9760099 () R-HSA-9760099 Reaction Name: AcK-NFE2L2 binds the GCLC gene See in Reactome R-HSA-9760103 () R-HSA-9760103 Reaction Name: AcK-NFE2L2 binds the GCLM gene See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-1989767 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989767 Reaction Name: Expression of TRIB3 See in Reactome R-HSA-8938251 ( R-HSA-8939246 ) R-HSA-8938251 Reaction Name: CSF2 (GM-CSF) gene expression is stimulated by RUNX1 and CREBBP See in Reactome R-HSA-1989748 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989748 Reaction Name: Expression of GRHL1 See in Reactome R-HSA-4395227 ( R-HSA-1912408 ) R-HSA-4395227 Reaction Name: CCND1:CREBBP binds NOTCH1 promoter See in Reactome R-HSA-1989779 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989779 Reaction Name: Expression of ANKRD1 See in Reactome R-HSA-1989759 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989759 Reaction Name: Expression of G0S2 See in Reactome R-HSA-1655848 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655848 Reaction Name: Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) See in Reactome R-HSA-1235070 ( R-HSA-1234158 ) R-HSA-1235070 Reaction Name: Expression of Erythropoietin (EPO) See in Reactome R-HSA-5660660 ( R-HSA-5621575 ) R-HSA-5660660 Reaction Name: p300 acetylates RELA subunit See in Reactome R-HSA-1989752 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989752 Reaction Name: Expression of TXNRD1 See in Reactome R-HSA-1989749 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989749 Reaction Name: Expression of ACOX1 See in Reactome R-HSA-1989761 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989761 Reaction Name: Expression of APOA5 See in Reactome R-HSA-1989768 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989768 Reaction Name: Expression of TIAM2 See in Reactome R-HSA-9604499 ( R-HSA-933541 ) R-HSA-9604499 Reaction Name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 See in Reactome R-HSA-9604664 ( R-HSA-9013695 ) R-HSA-9604664 Reaction Name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 See in Reactome R-HSA-5617896 ( R-HSA-5617472 ) R-HSA-5617896 Reaction Name: Retinoic acid activates HOXD4 chromatin See in Reactome R-HSA-9759364 () R-HSA-9759364 Reaction Name: AcK-NFE2L2-dependent TXNRD1 gene expression See in Reactome R-HSA-3322427 ( R-HSA-201722 ) R-HSA-3322427 Reaction Name: Beta-catenin recruits CBP/p300 See in Reactome R-HSA-1655826 ( R-HSA-1989781; R-HSA-2426168; R-HSA-400206 ) R-HSA-1655826 Reaction Name: Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) See in Reactome R-HSA-1989774 ( R-HSA-1989781; R-HSA-400206 ) R-HSA-1989774 Reaction Name: Expression of AGT See in Reactome R-HSA-6797993 ( R-HSA-6803204 ) R-HSA-6797993 Reaction Name: TP53 and CREBBP bind BNIP3L gene See in Reactome R-HSA-9759186 () R-HSA-9759186 Reaction Name: AcK-NFE2L2- dependent NQO1 gene expression See in Reactome R-HSA-9760081 () R-HSA-9760081 Reaction Name: CREBBP, EP300 acetylates NFE2L2 See in Reactome