DAR - Bologna Biocomputing Group

Search summary (Reactome ID: R-HSA-110357)

Number of enzymes:	4
Number of disease:	8
Number of reactomes:	6
Number of reactions:	23

Search results (Reactome ID: R-HSA-110357)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0001056	MUTYH	Q9UIF7	3.2.2.31	R-HSA-110330 R-HSA-110330 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected purine See in Reactome R-HSA-110331 R-HSA-110331 Reactome Name: Cleavage of the damaged purine See in Reactome R-HSA-110357 R-HSA-110357 Reactome Name: Displacement of DNA glycosylase by APEX1 See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73884 R-HSA-73884 Reactome Name: Base Excision Repair See in Reactome R-HSA-73927 R-HSA-73927 Reactome Name: Depurination See in Reactome R-HSA-73933 R-HSA-73933 Reactome Name: Resolution of Abasic Sites (AP sites) See in Reactome R-HSA-73929 R-HSA-73929 Reactome Name: Base-Excision Repair, AP Site Formation See in Reactome	DNA Repair	R-HSA-110237 ( R-HSA-110330 ) R-HSA-110237 Reaction Name: MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine See in Reactome R-HSA-110246 ( R-HSA-110331 ) R-HSA-110246 Reaction Name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH See in Reactome R-HSA-110355 ( R-HSA-110357 ) R-HSA-110355 Reaction Name: Displacement of MUTYH glycosylase by APEX1 at the AP site See in Reactome
MONDO:0004989	MUTYH	Q9UIF7	3.2.2.31	R-HSA-110330 R-HSA-110330 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected purine See in Reactome R-HSA-110331 R-HSA-110331 Reactome Name: Cleavage of the damaged purine See in Reactome R-HSA-110357 R-HSA-110357 Reactome Name: Displacement of DNA glycosylase by APEX1 See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73884 R-HSA-73884 Reactome Name: Base Excision Repair See in Reactome R-HSA-73927 R-HSA-73927 Reactome Name: Depurination See in Reactome R-HSA-73933 R-HSA-73933 Reactome Name: Resolution of Abasic Sites (AP sites) See in Reactome R-HSA-73929 R-HSA-73929 Reactome Name: Base-Excision Repair, AP Site Formation See in Reactome	DNA Repair	R-HSA-110237 ( R-HSA-110330 ) R-HSA-110237 Reaction Name: MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine See in Reactome R-HSA-110246 ( R-HSA-110331 ) R-HSA-110246 Reaction Name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH See in Reactome R-HSA-110355 ( R-HSA-110357 ) R-HSA-110355 Reaction Name: Displacement of MUTYH glycosylase by APEX1 at the AP site See in Reactome
MONDO:0007564	MUTYH	Q9UIF7	3.2.2.31	R-HSA-110330 R-HSA-110330 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected purine See in Reactome R-HSA-110331 R-HSA-110331 Reactome Name: Cleavage of the damaged purine See in Reactome R-HSA-110357 R-HSA-110357 Reactome Name: Displacement of DNA glycosylase by APEX1 See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73884 R-HSA-73884 Reactome Name: Base Excision Repair See in Reactome R-HSA-73927 R-HSA-73927 Reactome Name: Depurination See in Reactome R-HSA-73933 R-HSA-73933 Reactome Name: Resolution of Abasic Sites (AP sites) See in Reactome R-HSA-73929 R-HSA-73929 Reactome Name: Base-Excision Repair, AP Site Formation See in Reactome	DNA Repair	R-HSA-110237 ( R-HSA-110330 ) R-HSA-110237 Reaction Name: MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine See in Reactome R-HSA-110246 ( R-HSA-110331 ) R-HSA-110246 Reaction Name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH See in Reactome R-HSA-110355 ( R-HSA-110357 ) R-HSA-110355 Reaction Name: Displacement of MUTYH glycosylase by APEX1 at the AP site See in Reactome
MONDO:0007763	OGG1	O15527	4.2.99.18 3.2.2.-	R-HSA-110357 R-HSA-110357 Reactome Name: Displacement of DNA glycosylase by APEX1 See in Reactome R-HSA-110330 R-HSA-110330 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected purine See in Reactome R-HSA-110331 R-HSA-110331 Reactome Name: Cleavage of the damaged purine See in Reactome R-HSA-110329 R-HSA-110329 Reactome Name: Cleavage of the damaged pyrimidine See in Reactome R-HSA-110328 R-HSA-110328 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine See in Reactome R-HSA-5649702 R-HSA-5649702 Reactome Name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway See in Reactome	R-HSA-73927 R-HSA-73927 Reactome Name: Depurination See in Reactome R-HSA-73933 R-HSA-73933 Reactome Name: Resolution of Abasic Sites (AP sites) See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73884 R-HSA-73884 Reactome Name: Base Excision Repair See in Reactome R-HSA-73928 R-HSA-73928 Reactome Name: Depyrimidination See in Reactome R-HSA-73929 R-HSA-73929 Reactome Name: Base-Excision Repair, AP Site Formation See in Reactome	DNA Repair	R-HSA-110235 ( R-HSA-110330 ) R-HSA-110235 Reaction Name: OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine See in Reactome R-HSA-110236 ( R-HSA-110328 ) R-HSA-110236 Reaction Name: OGG1 glycosylase mediated recognition and binding of a formamidopyrimidine (FapyG) See in Reactome R-HSA-110243 ( R-HSA-110331 ) R-HSA-110243 Reaction Name: Excision of 8-oxoguanine by OGG1 glycosylase See in Reactome R-HSA-110244 ( R-HSA-110329 ) R-HSA-110244 Reaction Name: Excision of FapyG by OGG1 glycosylase See in Reactome R-HSA-110354 ( R-HSA-110357 ) R-HSA-110354 Reaction Name: Displacement of OGG1 glycosylase by APEX1 at the AP site See in Reactome R-HSA-5649701 ( R-HSA-5649702 ) R-HSA-5649701 Reaction Name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA See in Reactome
MONDO:0011971	UNG	P13051	3.2.2.27	R-HSA-110329 R-HSA-110329 Reactome Name: Cleavage of the damaged pyrimidine See in Reactome R-HSA-110328 R-HSA-110328 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine See in Reactome R-HSA-110357 R-HSA-110357 Reactome Name: Displacement of DNA glycosylase by APEX1 See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73928 R-HSA-73928 Reactome Name: Depyrimidination See in Reactome R-HSA-73884 R-HSA-73884 Reactome Name: Base Excision Repair See in Reactome R-HSA-73933 R-HSA-73933 Reactome Name: Resolution of Abasic Sites (AP sites) See in Reactome R-HSA-73929 R-HSA-73929 Reactome Name: Base-Excision Repair, AP Site Formation See in Reactome	DNA Repair	R-HSA-110156 ( R-HSA-110328 ) R-HSA-110156 Reaction Name: UNG glycosylase mediated recognition and binding of an uracil opposite to a guanine See in Reactome R-HSA-110157 ( R-HSA-110328 ) R-HSA-110157 Reaction Name: UNG glycosylase mediated recognition and binding of a 5-hydroxyuracil opposite to a guanine See in Reactome R-HSA-110215 ( R-HSA-110329 ) R-HSA-110215 Reaction Name: Cleavage of uracil by UNG glycosylase See in Reactome R-HSA-110217 ( R-HSA-110329 ) R-HSA-110217 Reaction Name: Cleavage of 5-hydroxyluracil by UNG glycosylase See in Reactome R-HSA-110349 ( R-HSA-110357 ) R-HSA-110349 Reaction Name: Displacement of UNG glycosylase by APEX1 at the AP site See in Reactome
MONDO:0012041	MUTYH	Q9UIF7	3.2.2.31	R-HSA-110330 R-HSA-110330 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected purine See in Reactome R-HSA-110331 R-HSA-110331 Reactome Name: Cleavage of the damaged purine See in Reactome R-HSA-110357 R-HSA-110357 Reactome Name: Displacement of DNA glycosylase by APEX1 See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73884 R-HSA-73884 Reactome Name: Base Excision Repair See in Reactome R-HSA-73927 R-HSA-73927 Reactome Name: Depurination See in Reactome R-HSA-73933 R-HSA-73933 Reactome Name: Resolution of Abasic Sites (AP sites) See in Reactome R-HSA-73929 R-HSA-73929 Reactome Name: Base-Excision Repair, AP Site Formation See in Reactome	DNA Repair	R-HSA-110237 ( R-HSA-110330 ) R-HSA-110237 Reaction Name: MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine See in Reactome R-HSA-110246 ( R-HSA-110331 ) R-HSA-110246 Reaction Name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH See in Reactome R-HSA-110355 ( R-HSA-110357 ) R-HSA-110355 Reaction Name: Displacement of MUTYH glycosylase by APEX1 at the AP site See in Reactome
MONDO:0014630	NTHL1	P78549	4.2.99.18 3.2.2.-	R-HSA-110329 R-HSA-110329 Reactome Name: Cleavage of the damaged pyrimidine See in Reactome R-HSA-110328 R-HSA-110328 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine See in Reactome R-HSA-110357 R-HSA-110357 Reactome Name: Displacement of DNA glycosylase by APEX1 See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73928 R-HSA-73928 Reactome Name: Depyrimidination See in Reactome R-HSA-73884 R-HSA-73884 Reactome Name: Base Excision Repair See in Reactome R-HSA-73933 R-HSA-73933 Reactome Name: Resolution of Abasic Sites (AP sites) See in Reactome R-HSA-73929 R-HSA-73929 Reactome Name: Base-Excision Repair, AP Site Formation See in Reactome	DNA Repair	R-HSA-110208 ( R-HSA-110328 ) R-HSA-110208 Reaction Name: NTHL1 glycosylase mediated recognition and binding of cytosine glycol See in Reactome R-HSA-110211 ( R-HSA-110328 ) R-HSA-110211 Reaction Name: NTHL1 glycosylase mediated recognition and binding of thymine glycol See in Reactome R-HSA-110212 ( R-HSA-110328 ) R-HSA-110212 Reaction Name: NTHL1 glycosylase mediated recognition and binding of dihydrouracil See in Reactome R-HSA-110213 ( R-HSA-110328 ) R-HSA-110213 Reaction Name: NTHL1 glycosylase mediated recognition and binding of formamidopyrimidine (FapyA) See in Reactome R-HSA-110224 ( R-HSA-110329 ) R-HSA-110224 Reaction Name: Cleavage of thymine glycol by NTHL1 glycosylase See in Reactome R-HSA-110226 ( R-HSA-110329 ) R-HSA-110226 Reaction Name: Cleavage of cytosine glycol by NTHL1 glycosylase See in Reactome R-HSA-110227 ( R-HSA-110329 ) R-HSA-110227 Reaction Name: Cleavage of dihydrouracil by NTHL1 glycosylase See in Reactome R-HSA-110229 ( R-HSA-110329 ) R-HSA-110229 Reaction Name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase See in Reactome R-HSA-110352 ( R-HSA-110357 ) R-HSA-110352 Reaction Name: Displacement of NTHL1 glycosylase by APEX1 at the AP site See in Reactome
MONDO:0023113	MUTYH	Q9UIF7	3.2.2.31	R-HSA-110330 R-HSA-110330 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected purine See in Reactome R-HSA-110331 R-HSA-110331 Reactome Name: Cleavage of the damaged purine See in Reactome R-HSA-110357 R-HSA-110357 Reactome Name: Displacement of DNA glycosylase by APEX1 See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73884 R-HSA-73884 Reactome Name: Base Excision Repair See in Reactome R-HSA-73927 R-HSA-73927 Reactome Name: Depurination See in Reactome R-HSA-73933 R-HSA-73933 Reactome Name: Resolution of Abasic Sites (AP sites) See in Reactome R-HSA-73929 R-HSA-73929 Reactome Name: Base-Excision Repair, AP Site Formation See in Reactome	DNA Repair	R-HSA-110237 ( R-HSA-110330 ) R-HSA-110237 Reaction Name: MUTYH mediated recognition and binding of an adenine opposite to an 8-oxoguanine See in Reactome R-HSA-110246 ( R-HSA-110331 ) R-HSA-110246 Reaction Name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH See in Reactome R-HSA-110355 ( R-HSA-110357 ) R-HSA-110355 Reaction Name: Displacement of MUTYH glycosylase by APEX1 at the AP site See in Reactome