DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q9Y5B0)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	5
Number of reactions:	18

Search results (UniProt accession: Q9Y5B0)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0011402	CTDP1	Q9Y5B0	3.1.3.16	R-HSA-75955 R-HSA-75955 Reactome Name: RNA Polymerase II Transcription Elongation See in Reactome R-HSA-112382 R-HSA-112382 Reactome Name: Formation of RNA Pol II elongation complex See in Reactome R-HSA-6796648 R-HSA-6796648 Reactome Name: TP53 Regulates Transcription of DNA Repair Genes See in Reactome R-HSA-113418 R-HSA-113418 Reactome Name: Formation of the Early Elongation Complex See in Reactome R-HSA-674695 R-HSA-674695 Reactome Name: RNA Polymerase II Pre-transcription Events See in Reactome	R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome	Gene expression (Transcription)	R-HSA-112379 ( R-HSA-112382; R-HSA-75955 ) R-HSA-112379 Reaction Name: Recruitment of elongation factors to form elongation complex See in Reactome R-HSA-112381 ( R-HSA-112382; R-HSA-75955 ) R-HSA-112381 Reaction Name: Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex See in Reactome R-HSA-112383 ( R-HSA-113418; R-HSA-75955 ) R-HSA-112383 Reaction Name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein See in Reactome R-HSA-112385 ( R-HSA-75955 ) R-HSA-112385 Reaction Name: Addition of nucleotides leads to transcript elongation See in Reactome R-HSA-112392 ( R-HSA-674695 ) R-HSA-112392 Reaction Name: Resumption of elongation after recovery from pausing See in Reactome R-HSA-112395 ( R-HSA-674695 ) R-HSA-112395 Reaction Name: Abortive termination of elongation after arrest See in Reactome R-HSA-112396 ( R-HSA-75955 ) R-HSA-112396 Reaction Name: Separation of elongating transcript from template See in Reactome R-HSA-113402 ( R-HSA-113418; R-HSA-75955 ) R-HSA-113402 Reaction Name: Formation of DSIF:NELF:early elongation complex See in Reactome R-HSA-113407 ( R-HSA-113418; R-HSA-75955 ) R-HSA-113407 Reaction Name: DSIF complex binds to RNA Pol II (hypophosphorylated) See in Reactome R-HSA-113409 ( R-HSA-674695 ) R-HSA-113409 Reaction Name: Abortive termination of early transcription elongation by DSIF:NELF See in Reactome R-HSA-113411 ( R-HSA-674695 ) R-HSA-113411 Reaction Name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing See in Reactome R-HSA-113412 ( R-HSA-75955 ) R-HSA-113412 Reaction Name: Pol II elongation complex moves on the template as transcript elongates See in Reactome R-HSA-113413 ( R-HSA-674695 ) R-HSA-113413 Reaction Name: TFIIS-mediated recovery of elongation from arrest See in Reactome R-HSA-113414 ( R-HSA-674695 ) R-HSA-113414 Reaction Name: 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest See in Reactome R-HSA-113429 ( R-HSA-674695 ) R-HSA-113429 Reaction Name: Elongating transcript encounters a lesion in the template See in Reactome R-HSA-6797606 ( R-HSA-6796648 ) R-HSA-6797606 Reaction Name: CDK12 phosphorylates RNA Pol II CTD at DNA repair genes See in Reactome R-HSA-6797616 ( R-HSA-6796648 ) R-HSA-6797616 Reaction Name: CCNK:CDK12 binds RNA Pol II at DNA repair genes See in Reactome R-HSA-6797712 ( R-HSA-6796648 ) R-HSA-6797712 Reaction Name: CDK12 stimulates expression of DNA repair genes See in Reactome