DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q9UBM7)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	3
Number of reactions:	3

Search results (UniProt accession: Q9UBM7)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010035	DHCR7	Q9UBM7	1.3.1.21	R-HSA-6807062 R-HSA-6807062 Reactome Name: Cholesterol biosynthesis via lathosterol See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome R-HSA-6807047 R-HSA-6807047 Reactome Name: Cholesterol biosynthesis via desmosterol See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-1655827 ( R-HSA-2426168 ) R-HSA-1655827 Reaction Name: Expression of 7-Dehydrocholesterol Reductase (DHCR7) See in Reactome R-HSA-196402 ( R-HSA-6807047 ) R-HSA-196402 Reaction Name: Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol See in Reactome R-HSA-6807055 ( R-HSA-6807062 ) R-HSA-6807055 Reaction Name: DHCR7 reduces 7-dehydroCHOL to CHOL See in Reactome
MONDO:0001149	DHCR7	Q9UBM7	1.3.1.21	R-HSA-6807062 R-HSA-6807062 Reactome Name: Cholesterol biosynthesis via lathosterol See in Reactome R-HSA-2426168 R-HSA-2426168 Reactome Name: Activation of gene expression by SREBF (SREBP) See in Reactome R-HSA-6807047 R-HSA-6807047 Reactome Name: Cholesterol biosynthesis via desmosterol See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1655829 R-HSA-1655829 Reactome Name: Regulation of cholesterol biosynthesis by SREBP (SREBF) See in Reactome R-HSA-191273 R-HSA-191273 Reactome Name: Cholesterol biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8957322 R-HSA-8957322 Reactome Name: Metabolism of steroids See in Reactome	Metabolism	R-HSA-1655827 ( R-HSA-2426168 ) R-HSA-1655827 Reaction Name: Expression of 7-Dehydrocholesterol Reductase (DHCR7) See in Reactome R-HSA-196402 ( R-HSA-6807047 ) R-HSA-196402 Reaction Name: Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol See in Reactome R-HSA-6807055 ( R-HSA-6807062 ) R-HSA-6807055 Reaction Name: DHCR7 reduces 7-dehydroCHOL to CHOL See in Reactome