DAR - Bologna Biocomputing Group

Search summary (UniProt accession: Q9NSU2)

Number of enzymes:	1
Number of disease:	4
Number of reactomes:	2
Number of reactions:	3

Search results (UniProt accession: Q9NSU2)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0012500	TREX1	Q9NSU2	3.1.11.2	R-HSA-3270619 R-HSA-3270619 Reactome Name: IRF3-mediated induction of type I IFN See in Reactome R-HSA-3248023 R-HSA-3248023 Reactome Name: Regulation by TREX1 See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1834941 R-HSA-1834941 Reactome Name: STING mediated induction of host immune responses See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-3134975 R-HSA-3134975 Reactome Name: Regulation of innate immune responses to cytosolic DNA See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome	Immune System	R-HSA-1834939 ( R-HSA-3270619 ) R-HSA-1834939 Reaction Name: STING recruits TBK1 and IRF3 See in Reactome R-HSA-3244605 ( R-HSA-3248023 ) R-HSA-3244605 Reaction Name: TREX1 binds retroviral-derived DNA See in Reactome R-HSA-3245943 ( R-HSA-3248023 ) R-HSA-3245943 Reaction Name: Viral DNA cleavage by TREX1 See in Reactome
MONDO:0008641	TREX1	Q9NSU2	3.1.11.2	R-HSA-3270619 R-HSA-3270619 Reactome Name: IRF3-mediated induction of type I IFN See in Reactome R-HSA-3248023 R-HSA-3248023 Reactome Name: Regulation by TREX1 See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1834941 R-HSA-1834941 Reactome Name: STING mediated induction of host immune responses See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-3134975 R-HSA-3134975 Reactome Name: Regulation of innate immune responses to cytosolic DNA See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome	Immune System	R-HSA-1834939 ( R-HSA-3270619 ) R-HSA-1834939 Reaction Name: STING recruits TBK1 and IRF3 See in Reactome R-HSA-3244605 ( R-HSA-3248023 ) R-HSA-3244605 Reaction Name: TREX1 binds retroviral-derived DNA See in Reactome R-HSA-3245943 ( R-HSA-3248023 ) R-HSA-3245943 Reaction Name: Viral DNA cleavage by TREX1 See in Reactome
MONDO:0009165	TREX1	Q9NSU2	3.1.11.2	R-HSA-3270619 R-HSA-3270619 Reactome Name: IRF3-mediated induction of type I IFN See in Reactome R-HSA-3248023 R-HSA-3248023 Reactome Name: Regulation by TREX1 See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1834941 R-HSA-1834941 Reactome Name: STING mediated induction of host immune responses See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-3134975 R-HSA-3134975 Reactome Name: Regulation of innate immune responses to cytosolic DNA See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome	Immune System	R-HSA-1834939 ( R-HSA-3270619 ) R-HSA-1834939 Reaction Name: STING recruits TBK1 and IRF3 See in Reactome R-HSA-3244605 ( R-HSA-3248023 ) R-HSA-3244605 Reaction Name: TREX1 binds retroviral-derived DNA See in Reactome R-HSA-3245943 ( R-HSA-3248023 ) R-HSA-3245943 Reaction Name: Viral DNA cleavage by TREX1 See in Reactome
MONDO:0007915	TREX1	Q9NSU2	3.1.11.2	R-HSA-3270619 R-HSA-3270619 Reactome Name: IRF3-mediated induction of type I IFN See in Reactome R-HSA-3248023 R-HSA-3248023 Reactome Name: Regulation by TREX1 See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1834941 R-HSA-1834941 Reactome Name: STING mediated induction of host immune responses See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-3134975 R-HSA-3134975 Reactome Name: Regulation of innate immune responses to cytosolic DNA See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome	Immune System	R-HSA-1834939 ( R-HSA-3270619 ) R-HSA-1834939 Reaction Name: STING recruits TBK1 and IRF3 See in Reactome R-HSA-3244605 ( R-HSA-3248023 ) R-HSA-3244605 Reaction Name: TREX1 binds retroviral-derived DNA See in Reactome R-HSA-3245943 ( R-HSA-3248023 ) R-HSA-3245943 Reaction Name: Viral DNA cleavage by TREX1 See in Reactome