DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0014527	SPRTN	Q9H040	3.4.24.-	R-HSA-110320 R-HSA-110320 Reactome Name: Translesion Synthesis by POLH See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73893 R-HSA-73893 Reactome Name: DNA Damage Bypass See in Reactome R-HSA-110313 R-HSA-110313 Reactome Name: Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template See in Reactome	DNA Repair	R-HSA-5654985 ( R-HSA-110320 ) R-HSA-5654985 Reaction Name: SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH See in Reactome R-HSA-5654986 ( R-HSA-110320 ) R-HSA-5654986 Reaction Name: SPRTN binds monoUb:K164-PCNA associated with POLH See in Reactome R-HSA-5654989 ( R-HSA-110320 ) R-HSA-5654989 Reaction Name: SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA See in Reactome